dual specificity mitogen-activated protein kinase kinase 1 isoform x2, maker-scaffold505_size153196-snap-gene-0.25 (gene) Tigriopus kingsejongensis

Overview


Name	dual specificity mitogen-activated protein kinase kinase 1 isoform x2
Unique Name	maker-scaffold505_size153196-snap-gene-0.25
Type	gene
Organism	Tigriopus kingsejongensis (Tigriopus kingsejongensis)

Associated RNAi Experiments

Nothing found

Homology

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BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. L. salmonis genes
Match: EMLSAG00000006911 (supercontig:LSalAtl2s:LSalAtl2s391:284955:287278:-1 gene:EMLSAG00000006911 transcript:EMLSAT00000006911 description:"maker-LSalAtl2s391-augustus-gene-2.16")

HSP 1 Score: 437.573 bits (1124), Expect = 7.007e-154
Identity = 210/274 (76.64%), Postives = 237/274 (86.50%), Query Frame = 0

Query:   52 TSVPDVALQLADVALADVDDEQRKRLEFFINQKKQLGELKGDEDFEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKKKARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLEISLGMYPIPPPDAASLIRIFGHEIA-DDPSILANPRTPRTPR 324
             S  D  +   +     V+D+QR+RL  F N+ +QLG+LKGDE+FEK+ ELG+GNGGVVHCV H+P+GT+MAKKMIHLEVKPA KKQI+TELKILH+CNSPYIVGFYGAYHS+GEINICMEYMDGGSLD+VLKK  +IPE+YSRKITYAVLRGLSYLRE H+IIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGS YSVASD+WSLGLSLLEISLGMYPIPPPD A+L  IFG +I  +D +I    R P+ PR
Sbjct:   48 NSAEDEEMHTNEGLFDVVNDKQRERLXXFXNRNEQLGDLKGDEEFEKLSELGSGNGGVVHCVLHRPSGTIMAKKMIHLEVKPATKKQIITELKILHKCNSPYIVGFYGAYHSDGEINICMEYMDGGSLDLVLKKTGKIPEKYSRKITYAVLRGLSYLRERHKIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGSPYSVASDVWSLGLSLLEISLGMYPIPPPDVAALTHIFGPQIGPEDVAIARANRIPKXPR 321

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BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. L. salmonis genes
Match: EMLSAG00000008861 (supercontig:LSalAtl2s:LSalAtl2s553:272490:273557:1 gene:EMLSAG00000008861 transcript:EMLSAT00000008861 description:"snap_masked-LSalAtl2s553-processed-gene-2.4")

HSP 1 Score: 177.178 bits (448), Expect = 2.393e-52
Identity = 112/306 (36.60%), Postives = 163/306 (53.27%), Query Frame = 0

Query:   94 EDFEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQIVTELKILHEC-NSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLK-----KKARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSF-VGTRSYMSPERL---QGSQYSVASDLWSLGLSLLEISLGMYPIPPPDAASLIRIFGHEIADDPSILANPRTPRTPRSPNVLGAPASGAKPMAIFELLEYIVNQPPPKLP--SRVFSEEMRDFVDRCLKKNFKERPDLATLM 387
            ED +   E+G G  G V+ +  + TGT+MA K I   V    +K+ + +L+++ +C + P IV F+GA   EG+  ICME MD  S D   K       +RIPE    KIT A +  L+YL+E  +IIHRDVKPSNIL++ +G IK+CDFG+SG+L+DS+A +   G R YM+PER+   +   Y V SD+WSLG++L+E+S G +P P                                            K  ++FE L+ +V+  PPKL     VF+ +  +FV+ CL K  + RP    L+
Sbjct:   62 EDLKDEGEIGRGAFGSVNRMSFRQTGTIMAXKRIRSTVDEKEQKEXLMDLEVVMKCADCPNIVSFFGAIFKEGDCWICMEIMDISS-DKFYKYIYEDMNSRIPENIIGKITVATVFALNYLKERLKIIHRDVKPSNILLDRKGNIKLCDFGISGRLVDSIAKTRDAGCRPYMAPERIDPQRARGYDVRSDVWSLGITLVELSTGKFPYP--------------------------------------------KWNSVFEQLQQVVHGDPPKLSPDDGVFTPQFLEFVNTCLIKEERRRPKYDKLL 322

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BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. L. salmonis genes
Match: EMLSAG00000012344 (supercontig:LSalAtl2s:LSalAtl2s900:149448:157557:1 gene:EMLSAG00000012344 transcript:EMLSAT00000012344 description:"maker-LSalAtl2s900-augustus-gene-0.17")

HSP 1 Score: 169.859 bits (429), Expect = 5.089e-47
Identity = 106/292 (36.30%), Postives = 150/292 (51.37%), Query Frame = 0

Query:   94 EDFEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQIVTELKI-LHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKKKAR-------IPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSF-VGTRSYMSPERL----QGSQYSVASDLWSLGLSLLEISLGMYPIPPPDAASLIRIFGHEIADDPSILANPRTPRTPRSPNVLGAPASGAKPMAIFELLEYIVNQPPPKLPSRVFSEEMRDFVDRC 372
            +D E I  LG G  GVV  +RH+ TGT++A K I + V     K+++ +L I +   + PY V FYGA   EG++ ICME MD  S+D    K  R       IPE    KI  +V++ L YL     +IHRDVKPSNIL++  G++K+CDFG+SG L +S+A +   G + YM+PER+      S Y V SD+WS G+S++EIS G +P                              +T  SP               F+ L+ +V+ PPP LP  +FS    DF+ + 
Sbjct:   46 DDLEGIGVLGRGAYGVVERMRHRQTGTILAVKRITVTVNRVETKRLLMDLDISMRTADCPYTVHFYGAMFREGDVWICMEVMDT-SVDNFYIKAFRGSETPVAIPEDVLGKIASSVIQALHYLHSRLSVIHRDVKPSNILISRNGDVKMCDFGISGYLHNSLAKTIDAGCKPYMAPERIDPTGNLSNYDVRSDVWSFGISMIEISTGKFPY-----------------------------QTWSSP---------------FDQLKQVVHDPPPTLPPNMFSSSYEDFIKKT 292

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BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. L. salmonis genes
Match: EMLSAG00000010179 (supercontig:LSalAtl2s:LSalAtl2s676:133631:149654:1 gene:EMLSAG00000010179 transcript:EMLSAT00000010179 description:"maker-LSalAtl2s676-augustus-gene-1.33")

HSP 1 Score: 162.155 bits (409), Expect = 6.825e-44
Identity = 104/305 (34.10%), Postives = 157/305 (51.48%), Query Frame = 0

Query:   94 EDFEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQIVTELKIL---HECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKK-KARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANS-FVGTRSYMSPERL---QGSQ--YSVASDLWSLGLSLLEISLGMYPIPPPDAASLIRIFGHEIADDPSILANPRTPRTPRSPNVLGAPASGAKPMAIFELLEYIVNQPPPKLPSRVFSEEMRDFVDRCLKKNFKERPDLATLMA 388
            EDFE + +LG G  G V  ++H+PTG ++A K +         K+I+ +L ++   H+C    IV   GA+ ++ ++ ICME M     D +LK  KA  PE    K+  A +  L+YL+E H +IHRDVKPSNIL+ + G +K+CDFG+SG+L+DS A +   G  +YM+PER+     SQ  Y + +D+WSLG++L+E++ G +P    D  +   +    + DDP +L                 P +G                         FS E R FV  CL KN+ +RP    L+ 
Sbjct: 1672 EDFELLGDLGNGTCGHVVKMQHRPTGQIIAVKQMRRTGDADENKRIIMDLDVVLKSHDCRE--IVLCLGAFITDSDVWICMELM-STCFDKLLKHIKAPXPEDICGKVAVATVNALNYLKERHGVIHRDVKPSNILLEASGCVKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPNPSQPDYDIRADVWSLGITLVELATGYFPY--RDCKTDFEVLTKVLTDDPPLL-----------------PRNGG------------------------FSHEFRSFVKDCLMKNYNDRPKYKKLLT 1930

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BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. L. salmonis genes
Match: EMLSAG00000011184 (supercontig:LSalAtl2s:LSalAtl2s760:424402:425388:1 gene:EMLSAG00000011184 transcript:EMLSAT00000011184 description:"augustus_masked-LSalAtl2s760-processed-gene-3.6")

HSP 1 Score: 113.62 bits (283), Expect = 8.681e-29
Identity = 66/201 (32.84%), Postives = 108/201 (53.73%), Query Frame = 0

Query:   95 DFEKIKELGAGNGGVVHCVRHKPTGTVMA-KKMIHLEVKPA-IKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKKK--ARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLEISLGMYPI 291
            DF+  + LG G  G V+  R K +  ++A K M   ++K A ++ Q+  E++I      P+I+  YG ++ E  + + +E+   G L  +LK +   R  E  + +  Y +   L YL  + ++IHRD+KP N+L++S+G +KI DFG S     S   +  GT  Y+SPE ++G  +    DLWSLG+   E  +G  P 
Sbjct:   52 DFDIGRPLGKGKFGNVYLAREKKSKFIVALKVMFKNQLKKANVEHQLRREIEIQXHLRHPHILRLYGYFYDETRVYLILEFASKGELYKLLKNEPLKRFEETLAARYIYQMSGALDYL-HSKKVIHRDIKPENLLLDSKGNLKIADFGWSVHAPSSRRGTMCGTLDYLSPEMIEGRSHDEKVDLWSLGILCFEFLVGKPPF 251

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BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. L. salmonis genes
Match: EMLSAG00000004239 (supercontig:LSalAtl2s:LSalAtl2s222:1379053:1391929:1 gene:EMLSAG00000004239 transcript:EMLSAT00000004239 description:"maker-LSalAtl2s222-augustus-gene-13.20")

HSP 1 Score: 115.161 bits (287), Expect = 3.962e-28
Identity = 76/244 (31.15%), Postives = 123/244 (50.41%), Query Frame = 0

Query:   55 PDVALQLADVALADVDDEQRKRLEFFINQKKQLG-ELKGDEDFEKIKELGAGNGGVVHCVRH---KPTGTVMAKKMIH---LEVKPAIKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKKKARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLEISLGMYPI 291
            PD       V     D+E     E  +N   + G E      FE ++ LG G+ G V  VR    K +GT+ A K++    L  +  ++ +   E  IL E   P++V  Y A+ +EG++ + ++++ GG L   L K+    E+  +     +   L +L  +  II+RD+KP N+L++S G I + DFG+S + I+  A SF GT  YM+PE +    +S A+D WS G+ + E+  G  P 
Sbjct:   40 PDTTDDKESVDFNKDDNEGSSEEEIEVNDITREGFERANSSQFELLQVLGQGSFGKVFLVRKIEGKDSGTLYAMKVLKKATLRFRDRVRTK--KERDILAEIEHPFMVKLYYAFQTEGKLYLILDFLRGGDLFTRLSKEIMFTEEDVKFYLAELALALIHLH-SLGIIYRDLKPENLLLDSNGHIAVTDFGLSKETIEDKAYSFCGTVEYMAPEIVNRKGHSFAADWWSFGILMYEMLTGQLPF 280

HSP 2 Score: 79.7221 bits (195), Expect = 2.615e-16
Identity = 70/232 (30.17%), Postives = 114/232 (49.14%), Query Frame = 0

Query:   81 INQKKQLGELKGDEDFEKIKELGAGNGGVVHCVR--HKPTGTVMAKKMIHLEVKPAIKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSL-DVVLKKKARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQ----GEIKICDFGVSGQLI--DSMANSFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLEISL-GMYPIP--PPDAASLI 300
            +N K ++   K  +++E +KEL  G G    C R  HK T    A K+I    +     ++     +L     P I+     +  +    +  EYM GG L D +L+++    E+ +R I   +   + YL +N  ++HRD+KP+NIL   +      ++ICDFG + QL   + +  +   T +Y++PE L+   Y  A D+WSLG+ LL I L G  P    P D+  +I
Sbjct:  422 VNLKDKIKLTKLSKEYE-VKEL-IGVGSYSECKRCIHKATNVEYAMKVIDKSKRDCNSDEVEI---LLRYGQHPNIISLKDVFEDKDFAYLIFEYMRGGELLDKILQQEI-FSEREARSIMERLTSAVHYLHQNG-VVHRDLKPANILYADKFGDPNTLRICDFGFAKQLRADNGLLMTPCYTANYVAPEVLKQQGYDAACDVWSLGV-LLHIMLSGKAPFANGPNDSMEVI 645

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BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. L. salmonis genes
Match: EMLSAG00000005433 (supercontig:LSalAtl2s:LSalAtl2s292:565959:573639:1 gene:EMLSAG00000005433 transcript:EMLSAT00000005433 description:"maker-LSalAtl2s292-augustus-gene-5.11")

HSP 1 Score: 111.309 bits (277), Expect = 4.898e-28
Identity = 92/313 (29.39%), Postives = 146/313 (46.65%), Query Frame = 0

Query:   80 FINQKKQL-GELKGDEDFEKIKELGAGNGGVVHCVRHK-PTGTVMAKKMIHLEVKPA-IKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLK--KKAR--IPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDS---MANSFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLEISLGMYPIPPPDAASLIRIFGHEIADDPSILANPRTPRTPRSPNVLGAPASGAKPMAIFELLEYIVNQPPPKLPSRVFSEEMRDFVDRCLKKNFKERPD 382
            F NQ+  + G+L   E+F   K +G G   VV+  + K    TV  KK+  LE+  +  +   V E+ +L + + P +V +  ++    E+NI +E  D G L  ++K  KK+R  +PE+   K    +   L Y+  + RI+HRD+KP+N+ + + GE K+ D G+ G+   S    A+S VGT  YMSPER+    Y+  SD+WSLG  L E++                                           L +P  G K M +  L + I +   P L S ++S+     VD  L+K+   RP+
Sbjct:    8 FTNQEDSIYGKL---ENFNVEKRIGKGQFSVVYRAKCKVDKRTVALKKVQILEMMDSKARVDCVKEILLLQQLDHPNVVRYLASFIENNELNIVLELADAGDLSWMIKYFKKSRKLLPEKTIWKYFVQICSALDYMH-SKRIMHRDIKPANVFITANGEAKLGDLGL-GRFFSSNTMAAHSLVGTPYYMSPERIHEEGYNFKSDIWSLGCLLYEMA------------------------------------------ALHSPFYGDK-MELSSLCQKIEHADYPTLSSELYSDSFISLVDETLQKDPSSRPN 272

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BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. L. salmonis genes
Match: EMLSAG00000003581 (supercontig:LSalAtl2s:LSalAtl2s196:150002:153649:-1 gene:EMLSAG00000003581 transcript:EMLSAT00000003581 description:"snap_masked-LSalAtl2s196-processed-gene-1.4")

HSP 1 Score: 111.309 bits (277), Expect = 3.201e-27
Identity = 68/194 (35.05%), Postives = 117/194 (60.31%), Query Frame = 0

Query:   76 RLEFFINQKKQ--LGELKGDED--FEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGS-LDVVLKKKARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMA--NSFVGTRSYMSPER 262
            R + ++  +KQ  LG+L+ D +  F K + +G G+ G  +      T  ++A K+I LE      + I  E+ +L +C+SP++  ++G+Y    ++ I MEY+ GGS LD  L K     E + + I   +L+GL YL    + +HRD+K +N+L+++ G++K+ DFGV+GQL ++ +  N+FVGT  +M+PER
Sbjct:   85 RYQTWVAPRKQPSLGQLRVDPELVFTKQERIGKGSFGEXYKGIDNRTQQIVAIKIIDLEEAEDEIEDIQQEIMVLSQCDSPFVTKYFGSYLKGTKLWIIMEYLGGGSALD--LMKAGSFEESHIQIILREILKGLDYLHSEKK-LHRDIKAANVLLSNTGDVKLADFGVAGQLTNTTSKRNTFVGTPFWMAPER 275

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BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. L. salmonis genes
Match: EMLSAG00000007994 (supercontig:LSalAtl2s:LSalAtl2s475:100675:125528:1 gene:EMLSAG00000007994 transcript:EMLSAT00000007994 description:"maker-LSalAtl2s475-augustus-gene-1.5")

HSP 1 Score: 112.079 bits (279), Expect = 5.068e-27
Identity = 92/293 (31.40%), Postives = 130/293 (44.37%), Query Frame = 0

Query:   93 DEDFEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQ-IVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKKKARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSFVGTRSYMSPE---RLQGSQYSVASDLWSLGLSLLEISLGMYPIPPPDAASLIRIFGHEIADDPSILANPRTPRTPRSPNVLGAPASGAKPMAIFELLEYIVNQPPPKLPSRVFSEEMRDFVDRCLKKNFKERP 381
            D  FE ++E+G G+ G V+  R +    V  KKM +   +   K Q I+ E++ L   + P  + + G Y  E  + + MEY  G + D++   K  + E+    I    L GLSYL    R IHRD+K  NIL+   G IK+ DFG +   I S ANSFVGT  +M+PE    +   QY    D+WSLG++ +E++                                      R P      A  A        L +I     P L S  +S+  R FVD CL+KN  ERP
Sbjct:   25 DRLFEDLREIGHGSFGAVYYAR-RGEEVVAIKKMSYSGKQSLEKWQDILKEIRFLRRLSHPNCITYNGXYLKEHTVWLVMEYCLGSASDIIEVHKTGLHEEEISAICAGCLAGLSYLHLQAR-IHRDIKAGNILLTDAGCIKLADFGSAS--IASPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELA-------------------------------------ERKPPYFNMNAMSA--------LYHIAQNDSPGLASPDWSDSFRHFVDXCLQKNPLERP 268

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BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. L. salmonis genes
Match: EMLSAG00000009535 (supercontig:LSalAtl2s:LSalAtl2s613:205707:209068:-1 gene:EMLSAG00000009535 transcript:EMLSAT00000009535 description:"maker-LSalAtl2s613-augustus-gene-1.23")

HSP 1 Score: 108.612 bits (270), Expect = 6.658e-26
Identity = 67/198 (33.84%), Postives = 106/198 (53.54%), Query Frame = 0

Query:   96 FEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKKKARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMAN---SFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLEISLGMYP 290
            + K++++G G  G V+      TG  +A K ++L+ +P  K+ I+ E+ ++     P +V F  AY    E+ + MEY+ GGSL  V+ +   + E     +   VL+ L +L   H +IHRD+K  NIL+   GE+K+ DFG   Q I S  N   + VGT  +M+P  +   QY    D+WSLG+  +E+  G  P
Sbjct:  238 YTKMEKIGQGASGTVYXAIETATGMEVAIKQMNLQQQPK-KELIINEIVVMKANKHPNVVNFLDAYLVGEELWVTMEYLPGGSLTDVVTETC-MDEGQIAAVCREVLQALDFLHRGH-VIHRDIKSDNILLGMDGEVKLTDFGFCAQ-ISSEQNKRTTMVGTPYWMAPXVVTRKQYGPKVDMWSLGIMAIEMIEGEPP 431

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BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. SwissProt
Match: gi|547916|sp|P36506.1|MP2K2_RAT (RecName: Full=Dual specificity mitogen-activated protein kinase kinase 2; Short=MAP kinase kinase 2; Short=MAPKK 2; AltName: Full=ERK activator kinase 2; AltName: Full=MAPK/ERK kinase 2; Short=MEK 2)

HSP 1 Score: 429.869 bits (1104), Expect = 6.718e-149
Identity = 217/368 (58.97%), Postives = 279/368 (75.82%), Query Frame = 0

Query:   20 CKKPPPLPLILPTDEPLSLGDEPDSAGLNRSTTSVPDVALQLADVALADVDDEQRKRLEFFINQKKQLGELKGDEDFEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKKKARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLEISLGMYPIPPPDAASLIRIFGHEIADDPSILANPRTPRTPRSPNVLGAPASGAKP-MAIFELLEYIVNQPPPKLPSRVFSEEMRDFVDRCLKKNFKERPDLATL 386
             ++ P LP  L  +  ++ G  P S G   S   + D+  +L ++   D+D++QRKRLE F+ QK ++GELK D+DFE+I ELGAGNGGVV   RH+P+G +MA+K+IHLE+KPA++ QI+ EL++LHECNSPYIVGFYGA++S+GEI+ICME+MDGGSLD VLK+  RIPE    K++ AVLRGL+YLRE H+I+HRDVKPSNILVNS+GEIK+CDFGVSGQLIDSMANSFVGTRSYMSPERLQG+ YSV SD+WS+GLSL+E+++G YPIPPPDA  L   FG  + D      +  +PR       +      ++P MAIFELL+YIVN+PPPKLPS VFS + ++FV++CL KN  ER DL  L
Sbjct:    3 ARRKPVLP-ALTINPTIAEGPSPTSEGA--SEAHLVDLQKKLEEL---DLDEQQRKRLEAFLTQKAKVGELK-DDDFERISELGAGNGGVVTKARHRPSGLIMARKLIHLEIKPAVRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEDILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVELAIGRYPIPPPDAKELEASFGRPVVDGADGEPHSVSPRPRPPGRPISGHGMDSRPAMAIFELLDYIVNEPPPKLPSGVFSSDFQEFVNKCLIKNPAERADLKLL 363

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BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. SwissProt
Match: gi|2499627|sp|Q63980.1|MP2K1_CRIGR (RecName: Full=Dual specificity mitogen-activated protein kinase kinase 1; Short=MAP kinase kinase 1; Short=MAPKK 1; AltName: Full=ERK activator kinase 1; AltName: Full=MAPK/ERK kinase 1; Short=MEK 1)

HSP 1 Score: 429.098 bits (1102), Expect = 1.307e-148
Identity = 211/354 (59.60%), Postives = 270/354 (76.27%), Query Frame = 0

Query:   35 PLSLGDEPDSAGLNRSTTSVPDVALQLADVALADVDDEQRKRLEFFINQKKQLGELKGDEDFEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKKKARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLEISLGMYPIPPPDAASLIRIFGHEIADDPSILANPRTPRTPRSPNVLGAPASGAKPMAIFELLEYIVNQPPPKLPSRVFSEEMRDFVDRCLKKNFKERPDLATLMA 388
            P+ L   PD + +N ++++  ++      +   +++++QR RLE F+ QK+++GELK D+DFEKI ELGAGNGGVV  V HKP+G VMA+K+IHLE+KPAI+ QI+ EL++LHECNSPYIVGFYG ++S+GEI+ICME+MDGGSLD VLKK  RIPEQ   K++ AV++GL+YLRE H+I+HRDVKPSNILVNS+GEIK+CDFGVSGQLIDSMANSFVGTRSYMSPERLQG+ YSV SD+WS+GLSL+E+++G YPIPPPDA  L  +FG ++  D    A            +         PMAIFELL+YIVN+PP KLPS VFS E +DFV++CL KN  ER DL  L+ 
Sbjct:    8 PIQLNPTPDGSAVNGTSSAETNLEALQKKLEELELEEQQRNRLEAFLTQKQKVGELK-DDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGVFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELLFGCQVEGDA---AETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPAKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLLV 357

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BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. SwissProt
Match: gi|341940966|sp|Q63932.2|MP2K2_MOUSE (RecName: Full=Dual specificity mitogen-activated protein kinase kinase 2; Short=MAP kinase kinase 2; Short=MAPKK 2; AltName: Full=ERK activator kinase 2; AltName: Full=MAPK/ERK kinase 2; Short=MEK 2)

HSP 1 Score: 429.098 bits (1102), Expect = 1.429e-148
Identity = 218/372 (58.60%), Postives = 278/372 (74.73%), Query Frame = 0

Query:   20 CKKPPPLPLILPTDEPLSLGDEPDSAGLNRSTTSVPDVALQLADVALADVDDEQRKRLEFFINQKKQLGELKGDEDFEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKKKARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLEISLGMYPIPPPDAASLIRIFGHEIADDPSILANPRTPRTPRSPNV----LGAPASGAKPMAIFELLEYIVNQPPPKLPSRVFSEEMRDFVDRCLKKNFKERPDLATLM 387
             ++ P LP  L  +  ++ G  P S G   S  ++ D+  +L ++   D+D++QRKRLE F+ QK ++GELK D+DFE+I ELGAGNGGVV   RH+P+G +MA+K+IHLE+KPA++ QI+ EL++LHECNSPYIVGFYGA++S+GEI+ICME+MDGGSLD VLK+  RIPE    K++ AVLRGL+YLRE H+I+HRDVKPSNILVNS+GEIK+CDFGVSGQLIDSMANSFVGTRSYMSPERLQG+ YSV SD+WS+GLSL+E+++G YPIPPPDA  L   FG  + D       P +      P      +G        MAIFELL+YIVN+PPPKLPS VFS + ++FV++CL KN  ER DL  LM
Sbjct:    3 ARRKPVLP-ALTINPTIAEGPSPTSEGA--SEANLVDLQKKLEEL---DLDEQQRKRLEAFLTQKAKVGELK-DDDFERISELGAGNGGVVTKARHRPSGLIMARKLIHLEIKPAVRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEDILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVELAIGRYPIPPPDAKELEASFGRPVVDGAD--GEPHSVSPRPRPPGRPISVGHGMDSRPAMAIFELLDYIVNEPPPKLPSGVFSSDFQEFVNKCLIKNPAERADLKLLM 365

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BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. SwissProt
Match: gi|73620960|sp|Q24324.2|DSOR1_DROME (RecName: Full=Dual specificity mitogen-activated protein kinase kinase dSOR1; Short=Downstream of RAF; Short=MAPKK)

HSP 1 Score: 427.172 bits (1097), Expect = 6.899e-148
Identity = 207/321 (64.49%), Postives = 251/321 (78.19%), Query Frame = 0

Query:   68 DVDDEQRKRLEFFINQKKQLGELKGDEDFEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKKKARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLEISLGMYPIPPPDAASLIRIFGHEIADDPSILANPRTPRTPRSPNVLGAPASGAKPMAIFELLEYIVNQPPPKLPSRVFSEEMRDFVDRCLKKNFKERPDLATLMA 388
            D+ D +RKR++ F++QK+++GEL  DED EK+ ELG+GNGGVV  VRH  T  +MA+K+IHLEVKPAIKKQI+ ELK+LHECN P+IVGFYGA++S+GEI+ICMEYMDGGSLD++LK+  RIPE    +IT AVL+GLSYLR+NH IIHRDVKPSNILVNS GEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQG+ YSV SD+WSLGLSL+E+++GMYPIPPP+ A+L  IF     +                    G P    + MAIFELL+YIVN+PPPKL  ++FS E +DFVD CLKK   ER DL TL++
Sbjct:   60 DMGDTERKRIKMFLSQKEKIGEL-SDEDLEKLGELGSGNGGVVMKVRHTHTHLIMARKLIHLEVKPAIKKQILRELKVLHECNFPHIVGFYGAFYSDGEISICMEYMDGGSLDLILKRAGRIPESILGRITLAVLKGLSYLRDNHAIIHRDVKPSNILVNSSGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPNTATLESIFADNAEES-------------------GQPTDEPRAMAIFELLDYIVNEPPPKLEHKIFSTEFKDFVDICLKKQPDERADLKTLLS 360

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BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. SwissProt
Match: gi|547915|sp|P36507.1|MP2K2_HUMAN (RecName: Full=Dual specificity mitogen-activated protein kinase kinase 2; Short=MAP kinase kinase 2; Short=MAPKK 2; AltName: Full=ERK activator kinase 2; AltName: Full=MAPK/ERK kinase 2; Short=MEK 2)

HSP 1 Score: 426.787 bits (1096), Expect = 1.062e-147
Identity = 215/368 (58.42%), Postives = 282/368 (76.63%), Query Frame = 0

Query:   20 CKKPPPLPLILPTDEPLSLGDEPDSAGLNRSTTSVPDVALQLADVALADVDDEQRKRLEFFINQKKQLGELKGDEDFEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKKKARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLEISLGMYPIPPPDAASLIRIFGHEIADDPSILANPRTPRTPRSPNVLGAPASGAKP-MAIFELLEYIVNQPPPKLPSRVFSEEMRDFVDRCLKKNFKERPDLATL 386
             ++ P LP  L  +  ++ G  P S G   S  ++ D+  +L ++ L   D++Q+KRLE F+ QK ++GELK D+DFE+I ELGAGNGGVV  V+H+P+G +MA+K+IHLE+KPAI+ QI+ EL++LHECNSPYIVGFYGA++S+GEI+ICME+MDGGSLD VLK+  RIPE+   K++ AVLRGL+YLRE H+I+HRDVKPSNILVNS+GEIK+CDFGVSGQLIDSMANSFVGTRSYM+PERLQG+ YSV SD+WS+GLSL+E+++G YPIPPPDA  L  IFG  + D      +  +PR       +      ++P MAIFELL+YIVN+PPPKLP+ VF+ + ++FV++CL KN  ER DL  L
Sbjct:    3 ARRKPVLP-ALTINPTIAEGPSPTSEGA--SEANLVDLQKKLEELEL---DEQQKKRLEAFLTQKAKVGELK-DDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQGTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRPPGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEFVNKCLIKNPAERADLKML 363

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BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. SwissProt
Match: gi|21542135|sp|Q10664.1|MEK2_CAEEL (RecName: Full=Dual specificity mitogen-activated protein kinase kinase mek-2; Short=MAP kinase kinase mek-2)

HSP 1 Score: 348.591 bits (893), Expect = 4.491e-117
Identity = 171/316 (54.11%), Postives = 230/316 (72.78%), Query Frame = 0

Query:   73 QRKRLEFFINQKKQLGELKGDEDFEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKKKARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLEISLGMYPIPPPDAASLIRIFGHEIADDPSILANPRTPRTPRSPNVLGAPASGAKPMAIFELLEYIVNQPPPKLPSRVFSEEMRDFVDRCLKKNFKERPDLATLMA 388
            Q +RL  F+  K+ + EL  D   +   ELG GNGGVV+   H+ TG +MA+K++HLE+KP++++QIV EL +LH+CNSP+IVGFYGA+    +I+ICMEYMDG SLD+VLKK  R+PE++  +I+ AV+RGL+YL++  +I+HRDVKPSN+LVNS GEIK+CDFGVSG LIDSMANSFVGTRSYM+PERL GS Y+++SD+WS GLSL+E+ +G YP+P P  A    +F   +A++   LA+     +   PN    P S    MAIFE+L+YIVN PPP LP R F++E+  FV +CL+K   ER  L +L A
Sbjct:   51 QTQRLSEFLQVKEGIKELSEDM-LQTEGELGHGNGGVVNKCVHRKTGVIMARKLVHLEIKPSVRQQIVKELAVLHKCNSPFIVGFYGAFVDNNDISICMEYMDGLSLDIVLKKVGRLPEKFVGRISVAVVRGLTYLKDEIKILHRDVKPSNMLVNSNGEIKLCDFGVSGMLIDSMANSFVGTRSYMAPERLTGSHYTISSDIWSFGLSLVELLIGRYPVPAPSQAEYATMFN--VAENEIELAD-----SLEEPNY--HPPSNPASMAIFEMLDYIVNGPPPTLPKRFFTDEVIGFVSKCLRKLPSERATLKSLTA 356

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BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. SwissProt
Match: gi|122065189|sp|Q99078.2|FUZ7_USTMA (RecName: Full=Dual specificity protein kinase FUZ7)

HSP 1 Score: 293.893 bits (751), Expect = 5.019e-95
Identity = 154/322 (47.83%), Postives = 209/322 (64.91%), Query Frame = 0

Query:   72 EQRKRLEFFINQKKQLGELKGDEDFEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKKKARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLEISLGMYPIPPPDAASLIRIFGHEIADDPSILANPRTP-----------RTPRSPNVLGAPASGAK-PMAIFELLEYIVNQPPPKLPSRVFSEEMRDFVDRCLKKNFKERP 381
            +Q   LE  +  K  L     +ED + + ELGAGNGG V  V H+ +GTVMAKK++ ++ KP+++KQI+ EL+ILHECNSPYIV FYGAY +E  I +CME+M   SLD + KK   I  +   KI  AV  GL+YL + HRIIHRDVKPSNILVN  G+IKICDFGVSG+LI+S+A++FVGT +YMSPER+QG QYSV SD+WSLG+S++E++LG +P    +         +   +D +   +P  P           +  R     G    G+   M+I +LL++IVN+PPPKLP   F + M +FV+ CL K+  +RP
Sbjct:   89 QQLANLELGVEYKLDLK----NEDLKTLSELGAGNGGTVTKVLHEKSGTVMAKKVVFIDAKPSVRKQILRELQILHECNSPYIVSFYGAYLNEPHICMCMEFMQKDSLDGIYKKYGPISPEICGKIAVAVSHGLTYLYDVHRIIHRDVKPSNILVNGAGQIKICDFGVSGELINSIADTFVGTSTYMSPERIQGDQYSVKSDVWSLGVSIIELALGRFPFAENEEDDDSDADNNYTNEDLAGTLSPTKPAPMISLGQNEKQRRRKSKPAGVSLEGSSHQMSILDLLQHIVNEPPPKLPEGRFPKHMEEFVNLCLLKDPAKRP 406

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BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. SwissProt
Match: gi|347595821|sp|P08018.4|PBS2_YEAST (RecName: Full=MAP kinase kinase PBS2; AltName: Full=Polymyxin B resistance protein 2; AltName: Full=Suppressor of fluoride sensitivity 4)

HSP 1 Score: 242.276 bits (617), Expect = 1.172e-72
Identity = 133/302 (44.04%), Postives = 178/302 (58.94%), Query Frame = 0

Query:   94 EDFEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKKKAR---IPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNS-QGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQG-----SQYSVASDLWSLGLSLLEISLGMYPIPPPDAASLIRIFGHEIADDPSILANPRTPRTPRSPNVLGAPASGAKPMAIFELLEYIVNQPPPKLPSRVFSEEMRDFVDRCLKKNFKERPDLATL 386
            ++ E + ELG GN G V  V HKPT  +MA K + LE+  A  +QI+ EL++LH+CNSPYIV FYGA+  EG + +CMEYMDGGSLD +  + +    I E     I  AV+ GL  L+E H IIHRDVKP+NIL ++ QG +K+CDFGVSG L+ S+A + +G +SYM+PER++      + Y+V SD+WSLGLS+LE++LG YP PP            E  D+                              IF  L  IV+ PPP+LPS  FS + +DFV  CL+K  + RP  A L
Sbjct:  358 DELEFLDELGHGNYGNVSKVLHKPTNVIMATKEVRLELDEAKFRQILMELEVLHKCNSPYIVDFYGAFFIEGAVYMCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHRDVKPTNILCSANQGTVKLCDFGVSGNLVASLAKTNIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPYPP------------ETYDN------------------------------IFSQLSAIVDGPPPRLPSDKFSSDAQDFVSLCLQKIPERRPTYAAL 617

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BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. SwissProt
Match: gi|115194|sp|P10506.1|BYR1_SCHPO (RecName: Full=Protein kinase byr1; AltName: Full=MAPK kinase; Short=MAPKK)

HSP 1 Score: 232.261 bits (591), Expect = 3.044e-72
Identity = 120/284 (42.25%), Postives = 173/284 (60.92%), Query Frame = 0

Query:   93 DEDFEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKKKARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLEISLGMYPIPPPDAASLIRIFGHEIADDPSILANPRTPRTPRSPNVLGAPASGAKPMAIFELLEYIVNQPPPKLPSRVFSEEMRDFVDRCLKKN 376
            +   E ++ LG GNGG V  V+H+     MA+K +++     ++KQI+ EL +LH C SPYIVGFYGA+  +  I++CMEYMD GSLD +L++   IP     KI  ++++GL YL     IIHRD+KPSN++VNS+GEIK+CDFGVSG+L++S+A +FVGT +YMSPER++G +Y+V SD+WSLG+S++E++    P            +     DD                            + I +LL  IV + PP+LPS  F E++R FVD CL K+
Sbjct:   63 NSSLEVVRHLGEGNGGAVSLVKHR--NIFMARKTVYVGSDSKLQKQILRELGVLHHCRSPYIVGFYGAFQYKNNISLCMEYMDCGSLDAILREGGPIPLDILGKIINSMVKGLIYLYNVLHIIHRDLKPSNVVVNSRGEIKLCDFGVSGELVNSVAQTFVGTSTYMSPERIRGGKYTVKSDIWSLGISIIELATQELP------------WSFSNIDD---------------------------SIGILDLLHCIVQEEPPRLPSS-FPEDLRLFVDACLHKD 304

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BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. SwissProt
Match: gi|2499634|sp|Q62862.1|MP2K5_RAT (RecName: Full=Dual specificity mitogen-activated protein kinase kinase 5; Short=MAP kinase kinase 5; Short=MAPKK 5; AltName: Full=MAPK/ERK kinase 5; Short=MEK 5)

HSP 1 Score: 234.572 bits (597), Expect = 6.882e-72
Identity = 124/296 (41.89%), Postives = 183/296 (61.82%), Query Frame = 0

Query:   93 DEDFEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKKKARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLEISLGMYPIPPPDAASLIRIFGHEIADDPSILANPRTPRTPRSPNVLGAPASGAKPMAIFELLEYIVNQPPPKLPSRVFSEEMRDFVDRCLKKNFKERPDLATLMA 388
            ++D      LG GNGG V+   H P+G ++A K+I L++   ++KQI++EL+IL++C+S YI+GFYGA+  E  I+IC E+MDGGSLDV  K    IPE    +I  AV++GL+YL  + +I+HRDVKPSN+LVN+ G++K+CDFGVS QL++S+A ++VGT +YM+PER+ G QY + SD+WSLG+S +E++LG +P P             +I  +   L                       P+   +LL+ IV++  P LP   FSE    F+ +C++K  KERP    LM 
Sbjct:  163 EQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRK----IPEHVLGRIAVAVVKGLTYLW-SLKILHRDVKPSNMLVNTSGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYP-------------QIQKNQGSLM----------------------PL---QLLQCIVDEDSPVLPLGEFSEPFVHFITQCMRKQPKERPAPEELMG 415

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BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. nr
Match: gi|1325328014|ref|XP_023345857.1| (dual specificity mitogen-activated protein kinase kinase 1-like [Eurytemora affinis])

HSP 1 Score: 541.962 bits (1395), Expect = 0.000e+0
Identity = 263/328 (80.18%), Postives = 291/328 (88.72%), Query Frame = 0

Query:   61 LADVALADVDDEQRKRLEFFINQKKQLGELKGDEDFEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKKKARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLEISLGMYPIPPPDAASLIRIFGHEIADDPSILANPRTPRTPRSPNVLGAPASGAKPMAIFELLEYIVNQPPPKLPSRVFSEEMRDFVDRCLKKNFKERPDLATLMA 388
            + D+ ++DVD+EQRKRLEFF NQKKQLGELK +EDFEKI ELGAGNGGVVHCVRHK TGTV+AKKMIHLEVKPAIKKQI+TEL+ILHECNSPYIVGFYGA+HS+GEINICMEYMDGGSLD+V+KK  RIPE+Y RKIT+AVLRGL YLRE H+IIHRDVKPSNILVNS GEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLE++LG YPIPPPD   L  IFG    +DP+ +    +PRTPR+P+      +G+KPMAIFELLEYIVNQPPP+LPSRVFS EMRDFVD CLKKN  ERPDLATLM+
Sbjct:   61 INDLVISDVDEEQRKRLEFFFNQKKQLGELKSEEDFEKISELGAGNGGVVHCVRHKQTGTVIAKKMIHLEVKPAIKKQIITELRILHECNSPYIVGFYGAFHSDGEINICMEYMDGGSLDLVIKKTGRIPEKYLRKITFAVLRGLQYLREKHQIIHRDVKPSNILVNSAGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLEMALGCYPIPPPDPNYLANIFGPVFMEDPANMMPVPSPRTPRTPH------TGSKPMAIFELLEYIVNQPPPRLPSRVFSCEMRDFVDICLKKNPGERPDLATLMS 382

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BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. nr
Match: gi|1022773995|gb|KZS18033.1| (Dual specificity mitogen-activated protein kinase kinase dSOR1 [Daphnia magna])

HSP 1 Score: 472.626 bits (1215), Expect = 1.074e-162
Identity = 230/346 (66.47%), Postives = 284/346 (82.08%), Query Frame = 0

Query:   43 DSAGLNRSTTSVPDVALQLADVALADVDDEQRKRLEFFINQKKQLGELKGDEDFEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKKKARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLEISLGMYPIPPPDAASLIRIFGHEIADDPSILANPRTPRTPRSPNVLGAPASGAKPMAIFELLEYIVNQPPPKLPSRVFSEEMRDFVDRCLKKNFKERPDLATLMA 388
            DS       T++  +  QL ++   D+DD QR+RL  F++QK+++GEL  D+DF+K+ ELGAGNGGVV  VRH+P+G +MA+K+IHLEVKPAIKKQI+ ELK+LHECNSP+IVGFYGA++S+GEI+ICMEYMDGGSLD++LKK  +IPEQY  KIT AVL+GLSYLR+ H+IIHRDVKPSNILVNS+GEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQG+ YS+ SD+WSLGLSL+E+++GMYPIPPPD  +L  IFG + ++DP  +    + R+PR     G  ++G +PMAIFELL+YIVN+PPPKLPS VFS E +DFVDRCLKKN  ERP L TLM 
Sbjct:   56 DSGNTTMGNTTLEALQRQLEEL---DIDDLQRQRLHKFLSQKQEVGELT-DDDFDKLGELGAGNGGVVTKVRHRPSGLIMARKLIHLEVKPAIKKQIIRELKVLHECNSPHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGKIPEQYLGKITIAVLKGLSYLRDKHQIIHRDVKPSNILVNSRGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSIQSDVWSLGLSLVEMAIGMYPIPPPDPQALAAIFGAKFSEDPDNMTPSPSSRSPRQSQFPGGVSNGPRPMAIFELLDYIVNEPPPKLPSGVFSVEFKDFVDRCLKKNPAERPALRTLMG 397

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BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. nr
Match: gi|669659202|gb|AII25437.1| (MEK [Eriocheir sinensis])

HSP 1 Score: 456.062 bits (1172), Expect = 1.236e-156
Identity = 227/349 (65.04%), Postives = 276/349 (79.08%), Query Frame = 0

Query:   40 DEPDSAGLNRSTTSVPDVALQ--LADVALADVDDEQRKRLEFFINQKKQLGELKGDEDFEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKKKARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLEISLGMYPIPPPDAASLIRIFGHEIADDPSILANPRTPRTPRSPNVLGAPASGAKPMAIFELLEYIVNQPPPKLPSRVFSEEMRDFVDRCLKKNFKERPDLATL 386
            D P       +T S   V+L+  L  +   D+DD QR+R+E F+NQK+++GEL  D DFEK+ ELGAGNGGVV+  RHKP+G +MA+K+IHLEVKPAI+ QI+ ELK+LHECNSP+IVGFYGA++SEGEI+ICMEYMDGGSLD+ LKK  RIPE    KI   VL+GL+YLRE H+IIHRDVKPSNILVNS+GEIKICDFGVSGQLIDSMAN+FVGTRSYMSPERL G  YSVASD+WSLGLSL+E+++GMYPIPPPD ++L +IFG ++    S+  +P T R+PRS  + G P    +PMAIFELL+YIVN+PPP+LP  VFS E  D VDRCLKK+  ER DL TL
Sbjct:   28 DTPQRKASTGATGSFGTVSLESLLKCIQELDMDDTQRRRMEIFLNQKQKVGELNAD-DFEKLGELGAGNGGVVNKERHKPSGLIMARKLIHLEVKPAIRNQIIRELKVLHECNSPFIVGFYGAFYSEGEISICMEYMDGGSLDLCLKKAIRIPESILAKICSTVLKGLAYLREKHQIIHRDVKPSNILVNSRGEIKICDFGVSGQLIDSMANTFVGTRSYMSPERLNGDHYSVASDIWSLGLSLVEMAIGMYPIPPPDPSTLKKIFGSKVE---SVSPSP-TSRSPRSAGLPGEP----RPMAIFELLDYIVNEPPPRLPPGVFSSEFVDLVDRCLKKSPSERADLTTL 367

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BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. nr
Match: gi|939679521|ref|XP_014285145.1| (PREDICTED: dual specificity mitogen-activated protein kinase kinase dSOR1 [Halyomorpha halys])

HSP 1 Score: 455.677 bits (1171), Expect = 1.490e-156
Identity = 231/350 (66.00%), Postives = 276/350 (78.86%), Query Frame = 0

Query:   42 PDSAGLNRST----TSVPDVALQLADVALADVDDEQRKRLEFFINQKKQLGELKGDEDFEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKKKARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLEISLGMYPIPPPDAASLIRIFGHEIADDPSILANPRTPRTPRSPNVLGAPASGAKPMAIFELLEYIVNQPPPKLPSRVFSEEMRDFVDRCLKKNFKERPDLATLM 387
            P S    RST    TS+  +  +L ++   D+DD QRKR+EFF+ QK+++GEL  D+DFEK+ ELGAGNGGVV  V+HK +G +MA+K+IHLEVKPAIKKQI+ ELK+LHECN  +IVGFYGA++S+GEI+ICMEYMDGGSLD++LKK  RIPE     IT AVL+GLSYLR+ H I+HRDVKPSNILVNS GEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQG+ YSV SD+WSLGLSL+E+++GMYPIPPPDA +L  IFG    D+ S     +T  +P   N      SG +PMAIFELL+YIVN+PPPKLPS +FS E +DFVDRCLKKN  ER DL TLM
Sbjct:   30 PKSEASERSTLVGKTSIEVLQERLEEL---DMDDTQRKRMEFFLCQKEKIGELS-DDDFEKLGELGAGNGGVVMKVKHKSSGLIMARKLIHLEVKPAIKKQIIRELKVLHECNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPEPILGTITAAVLKGLSYLRDKHAIMHRDVKPSNILVNSGGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPIPPPDAKTLAAIFGPSKEDEES-----QTQVSPVHGN-----GSGPRPMAIFELLDYIVNEPPPKLPSGIFSNEFKDFVDRCLKKNPAERADLKTLM 365

[Close]

BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. nr
Match: gi|558190055|ref|XP_006129229.1| (PREDICTED: dual specificity mitogen-activated protein kinase kinase 1 isoform X2 [Pelodiscus sinensis])

HSP 1 Score: 454.907 bits (1169), Expect = 2.650e-156
Identity = 221/353 (62.61%), Postives = 279/353 (79.04%), Query Frame = 0

Query:   35 PLSLGDEPDSAGLNRSTTSVPDVALQLADVALADVDDEQRKRLEFFINQKKQLGELKGDEDFEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKKKARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLEISLGMYPIPPPDAASLIRIFGHEIADDPSILANPRTPRTPRSPNVLGAPASGAKPMAIFELLEYIVNQPPPKLPSRVFSEEMRDFVDRCLKKNFKERPDLATLM 387
            P+ L   PDS+ +N ++T+  ++      +   ++D++QRKRLE F+ QK+++GELK D+DFEKI ELGAGNGGVV  V HKP+G +MA+K+IHLE+KPAI+ QI+ EL++LHECNSPYIVGFYGA++S+GEI+ICME+MDGGSLD VLKK  RIPEQ   K++ AV++GL+YLRE H+I+HRDVKPSNILVNS+GEIK+CDFGVSGQLIDSMANSFVGTRSYMSPERLQG+ YSV SD+WS+GLSL+E+++G YPIPPPD+  L  +FG  +  D S+       RTP  P     P S   PMAIFELL+YIVN+PPPKLP+ VFS E +DFV++CL KN  ER DL  LM
Sbjct:    8 PIQLNPAPDSSTINGTSTAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELK-DDDFEKISELGAGNGGVVFKVSHKPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAIGRYPIPPPDSKELELMFGCPVEGDSSVSETSPRQRTPGRPMSSYGPDS-RPPMAIFELLDYIVNEPPPKLPNGVFSPEFQDFVNKCLIKNPAERADLKQLM 358

[Close]

BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. nr
Match: gi|1339053585|ref|XP_023715161.1| (dual specificity mitogen-activated protein kinase kinase dSOR1-like isoform X4 [Cryptotermes secundus] >gi|1330898217|gb|PNF25934.1| Dual specificity mitogen-activated protein kinase kinase dSOR1 [Cryptotermes secundus])

HSP 1 Score: 452.981 bits (1164), Expect = 2.875e-156
Identity = 220/319 (68.97%), Postives = 262/319 (82.13%), Query Frame = 0

Query:   69 VDDEQRKRLEFFINQKKQLGELKGDEDFEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKKKARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLEISLGMYPIPPPDAASLIRIFGHEIADDPSILANPRTPRTPRSPNVLGAPASGAKPMAIFELLEYIVNQPPPKLPSRVFSEEMRDFVDRCLKKNFKERPDLATLM 387
            +DD QRKR+EFF+ QK+++GEL  D+DF+K+ ELGAGNGGVV  VRH+ +G +MA+K+IHLEVKPAIKKQI+ ELK+LH+CN  +IVGFYGA++S+GEI+ICMEYMDGGSLD++LKK  RIPE     IT AVL+GLSYLR+ H IIHRDVKPSNILVNS GEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQG+ YSV SD+WSLGLSL+E++LGMYPIPPPDA +L  IFG     D    A+   P +P + N    P SG +PMAIFELL+YIVN+PPPKLP+ +FS   ++FVD CLKKN  ERPDL TLM
Sbjct:    1 MDDTQRKRMEFFLCQKEKIGELS-DDDFDKLGELGAGNGGVVTKVRHRSSGLIMARKLIHLEVKPAIKKQIIRELKVLHDCNFAHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILGTITSAVLKGLSYLRDKHAIIHRDVKPSNILVNSGGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMALGMYPIPPPDAKTLAAIFGQTAESD----AHNHVPPSPVNSNNFQGP-SGPRPMAIFELLDYIVNEPPPKLPAGIFSASFKNFVDSCLKKNPAERPDLKTLM 313

[Close]

BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. nr
Match: gi|591369443|ref|XP_007059554.1| (PREDICTED: dual specificity mitogen-activated protein kinase kinase 1 isoform X2 [Chelonia mydas] >gi|1344884213|ref|XP_023964912.1| dual specificity mitogen-activated protein kinase kinase 1 isoform X2 [Chrysemys picta bellii])

HSP 1 Score: 454.136 bits (1167), Expect = 5.160e-156
Identity = 224/354 (63.28%), Postives = 281/354 (79.38%), Query Frame = 0

Query:   35 PLSLGDEPDSAGLNRSTTSVPDVALQLADVALADVDDEQRKRLEFFINQKKQLGELKGDEDFEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKKKARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLEISLGMYPIPPPDAASLIRIFGHEI-ADDPSILANPRTPRTPRSPNVLGAPASGAKPMAIFELLEYIVNQPPPKLPSRVFSEEMRDFVDRCLKKNFKERPDLATLM 387
            P+ L   PDS+ +N ++T+  ++      +   ++D++QRKRLE F+ QK+++GELK D+DFEKI ELGAGNGGVV  V HKP+G +MA+K+IHLE+KPAI+ QI+ EL++LHECNSPYIVGFYGA++S+GEI+ICME+MDGGSLD VLKK  RIPEQ   K++ AV++GL+YLRE H+I+HRDVKPSNILVNS+GEIK+CDFGVSGQLIDSMANSFVGTRSYMSPERLQG+ YSV SD+WS+GLSL+E+++G YPIPPPD+  L  +FG  +  D P    +PR  RTP  P     P S   PMAIFELL+YIVN+PPPKLPS VFS E +DFV++CL KN  ER DL  LM
Sbjct:    8 PIQLNPAPDSSTINGTSTAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELK-DDDFEKISELGAGNGGVVFKVSHKPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAIGRYPIPPPDSKELELMFGCPVEGDSPVSETSPRQ-RTPGRPMSSYGPDS-RPPMAIFELLDYIVNEPPPKLPSGVFSPEFQDFVNKCLIKNPAERADLKQLM 358

[Close]

BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. nr
Match: gi|504130436|ref|XP_004578017.1| (PREDICTED: dual specificity mitogen-activated protein kinase kinase 1 [Ochotona princeps])

HSP 1 Score: 453.751 bits (1166), Expect = 8.220e-156
Identity = 221/354 (62.43%), Postives = 282/354 (79.66%), Query Frame = 0

Query:   35 PLSLGDEPDSAGLNRSTTSVPDVALQLADVALADVDDEQRKRLEFFINQKKQLGELKGDEDFEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKKKARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLEISLGMYPIPPPDAASLIRIFGHEIADDPSILANPRTPRTPRSPNVLGAPASGAK-PMAIFELLEYIVNQPPPKLPSRVFSEEMRDFVDRCLKKNFKERPDLATLM 387
            P+ L   PD + +N ++++  ++      +   ++D++QRKRLE F+ QK+++GELK D+DFEKI ELGAGNGGVV  V HKP+G VMA+K+IHLE+KPAI+ QI+ EL++LHECNSPYIVGFYGA++S+GEI+ICME+MDGGSLD VLKK  RIPEQ   K++ AV++GL+YLRE H+I+HRDVKPSNILVNS+GEIK+CDFGVSGQLIDSMANSFVGTRSYMSPERLQG+ YSV SD+WS+GLSL+E+++G YPIPPPDA  L  +FG ++  + +    P  PRTP  P  L +    ++ PMAIFELL+YIVN+PPPKLPS VFS E +DFV++CL KN  ER DL  LM
Sbjct:    8 PIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELK-DDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELLFGCQVEGEAA--ETPARPRTPGRP--LSSYGMDSRPPMAIFELLDYIVNEPPPKLPSAVFSLEFQDFVNKCLIKNPAERADLKQLM 356

[Close]

BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. nr
Match: gi|1339039119|ref|XP_023725996.1| (dual specificity mitogen-activated protein kinase kinase dSOR1-like [Cryptotermes secundus] >gi|1339039123|ref|XP_023726159.1| dual specificity mitogen-activated protein kinase kinase dSOR1-like [Cryptotermes secundus] >gi|1339039125|ref|XP_023726238.1| dual specificity mitogen-activated protein kinase kinase dSOR1-like [Cryptotermes secundus] >gi|1330935890|gb|PNF43837.1| Dual specificity mitogen-activated protein kinase kinase dSOR1 [Cryptotermes secundus] >gi|1330935892|gb|PNF43839.1| Dual specificity mitogen-activated protein kinase kinase dSOR1 [Cryptotermes secundus])

HSP 1 Score: 453.751 bits (1166), Expect = 1.043e-155
Identity = 221/338 (65.38%), Postives = 270/338 (79.88%), Query Frame = 0

Query:   50 STTSVPDVALQLADVALADVDDEQRKRLEFFINQKKQLGELKGDEDFEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKKKARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLEISLGMYPIPPPDAASLIRIFGHEIADDPSILANPRTPRTPRSPNVLGAPASGAKPMAIFELLEYIVNQPPPKLPSRVFSEEMRDFVDRCLKKNFKERPDLATLM 387
            + TS+  + ++L ++ +   DD QRKR+EFF+ QK+++GEL  D+DFEK+ ELG GNGGVV  V H+ +G +MA+K+IHLEVKPAIKKQI+ ELK+LH+CN  +IVGFYGA++S+GEI+ICMEYMDGGSLD++LKK  RIPE   R IT AVL+GLSYLR+ H IIHRDVKPSNILVNS GEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQG+ YSV SD+WSLGLSL+E++LGMYPIPPPDA +L  IFG  +  D         P +P + N L   ++G +PMAIFELL+YIVN+PPPKLP+ +F+    DFVD CLKKN  ERPDL TLM
Sbjct:   38 AKTSIEALQVRLEELQM---DDTQRKRMEFFLCQKEKIGEL-SDDDFEKLGELGTGNGGVVMKVMHRSSGLIMARKLIHLEVKPAIKKQIIRELKVLHDCNFTHIVGFYGAFYSDGEISICMEYMDGGSLDLILKKAGRIPESILRTITSAVLKGLSYLRDKHAIIHRDVKPSNILVNSAGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMALGMYPIPPPDAKTLRAIFGERMDSD----NQNHVPSSPVNSNYLQG-SNGPRPMAIFELLDYIVNEPPPKLPTGIFTTSFEDFVDSCLKKNPTERPDLKTLM 366

[Close]

BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. nr
Match: gi|556958571|ref|XP_005990160.1| (PREDICTED: dual specificity mitogen-activated protein kinase kinase 1 [Latimeria chalumnae])

HSP 1 Score: 452.595 bits (1163), Expect = 2.047e-155
Identity = 220/354 (62.15%), Postives = 277/354 (78.25%), Query Frame = 0

Query:   35 PLSLGDEPDSAGLNRSTTSVPDVALQLADVALADVDDEQRKRLEFFINQKKQLGELKGDEDFEKIKELGAGNGGVVHCVRHKPTGTVMAKKMIHLEVKPAIKKQIVTELKILHECNSPYIVGFYGAYHSEGEINICMEYMDGGSLDVVLKKKARIPEQYSRKITYAVLRGLSYLRENHRIIHRDVKPSNILVNSQGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGSQYSVASDLWSLGLSLLEISLGMYPIPPPDAASLIRIFGHEIADDPSILANPRTPRTPRSPNVLGAPASGAKPMAIFELLEYIVNQPPPKLPSRVFSEEMRDFVDRCLKKNFKERPDLATLMA 388
            P+ L   PD + +N ++++  ++      +   ++D++QRKRLE F+ QK+++GELK D+DFEKI ELGAGNGGVV  V HKP+  +MA+K+IHLE+KPAI+ QI+ EL++LHECNSPYIVGFYGA++S+GEI+ICME+MDGGSLD VLKK  RIPEQ   K++ AV++GL+YLRE H+I+HRDVKPSNILVNS+GEIK+CDFGVSGQLIDSMANSFVGTRSYMSPERLQG+ YSV SD+WS+GLSL+E+++G YPIPPPD   L +IFG  +  D +       PR P  P     P S   PMAIFELL+YIVN+PPPKLPS VFS E +DFV++CL KN  ER DL  LMA
Sbjct:    9 PIQLNPTPDGSTINGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELK-DDDFEKICELGAGNGGVVFKVSHKPSSLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDPKELEQIFGCPVEGDSTSSETSARPRPPGHPMSSFGPDS-RPPMAIFELLDYIVNEPPPKLPSNVFSSEFQDFVNKCLIKNPAERADLKQLMA 360

The following BLAST results are available for this feature:

BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. L. salmonis genes
BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. SwissProt
BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. nr

BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. L. salmonis genes
Analysis Date: 2018-04-19 (T. kinsejongensis vs L. Salmonis peptides)
Total hits: 25


Match Name	E-value	Identity	Description
EMLSAG00000006911	7.007e-154	76.64	supercontig:LSalAtl2s:LSalAtl2s391:284955:287278:-...	[more]
EMLSAG00000008861	2.393e-52	36.60	supercontig:LSalAtl2s:LSalAtl2s553:272490:273557:1...	[more]
EMLSAG00000012344	5.089e-47	36.30	supercontig:LSalAtl2s:LSalAtl2s900:149448:157557:1...	[more]
EMLSAG00000010179	6.825e-44	34.10	supercontig:LSalAtl2s:LSalAtl2s676:133631:149654:1...	[more]
EMLSAG00000011184	8.681e-29	32.84	supercontig:LSalAtl2s:LSalAtl2s760:424402:425388:1...	[more]
EMLSAG00000004239	3.962e-28	31.15	supercontig:LSalAtl2s:LSalAtl2s222:1379053:1391929...	[more]
EMLSAG00000005433	4.898e-28	29.39	supercontig:LSalAtl2s:LSalAtl2s292:565959:573639:1...	[more]
EMLSAG00000003581	3.201e-27	35.05	supercontig:LSalAtl2s:LSalAtl2s196:150002:153649:-...	[more]
EMLSAG00000007994	5.068e-27	31.40	supercontig:LSalAtl2s:LSalAtl2s475:100675:125528:1...	[more]
EMLSAG00000009535	6.658e-26	33.84	supercontig:LSalAtl2s:LSalAtl2s613:205707:209068:-...	[more]

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BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. SwissProt
Analysis Date: 2018-04-19 (T. kingejongensis peptided Blastp vs. SwissProt)
Total hits: 25


Match Name	E-value	Identity	Description
gi\|547916\|sp\|P36506.1\|MP2K2_RAT	6.718e-149	58.97	RecName: Full=Dual specificity mitogen-activated p...	[more]
gi\|2499627\|sp\|Q63980.1\|MP2K1_CRIGR	1.307e-148	59.60	RecName: Full=Dual specificity mitogen-activated p...	[more]
gi\|341940966\|sp\|Q63932.2\|MP2K2_MOUSE	1.429e-148	58.60	RecName: Full=Dual specificity mitogen-activated p...	[more]
gi\|73620960\|sp\|Q24324.2\|DSOR1_DROME	6.899e-148	64.49	RecName: Full=Dual specificity mitogen-activated p...	[more]
gi\|547915\|sp\|P36507.1\|MP2K2_HUMAN	1.062e-147	58.42	RecName: Full=Dual specificity mitogen-activated p...	[more]
gi\|21542135\|sp\|Q10664.1\|MEK2_CAEEL	4.491e-117	54.11	RecName: Full=Dual specificity mitogen-activated p...	[more]
gi\|122065189\|sp\|Q99078.2\|FUZ7_USTMA	5.019e-95	47.83	RecName: Full=Dual specificity protein kinase FUZ7	[more]
gi\|347595821\|sp\|P08018.4\|PBS2_YEAST	1.172e-72	44.04	RecName: Full=MAP kinase kinase PBS2; AltName: Ful...	[more]
gi\|115194\|sp\|P10506.1\|BYR1_SCHPO	3.044e-72	42.25	RecName: Full=Protein kinase byr1; AltName: Full=M...	[more]
gi\|2499634\|sp\|Q62862.1\|MP2K5_RAT	6.882e-72	41.89	RecName: Full=Dual specificity mitogen-activated p...	[more]

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BLAST of dual specificity mitogen-activated protein kinase kinase 1 isoform x2 vs. nr
Analysis Date: 2018-05-15 (T. kingsejongensis proteins Blastp vs. NR)
Total hits: 25


Match Name	E-value	Identity	Description
gi\|1325328014\|ref\|XP_023345857.1\|	0.000e+0	80.18	dual specificity mitogen-activated protein kinase ...	[more]
gi\|1022773995\|gb\|KZS18033.1\|	1.074e-162	66.47	Dual specificity mitogen-activated protein kinase ...	[more]
gi\|669659202\|gb\|AII25437.1\|	1.236e-156	65.04	MEK [Eriocheir sinensis]	[more]
gi\|939679521\|ref\|XP_014285145.1\|	1.490e-156	66.00	PREDICTED: dual specificity mitogen-activated prot...	[more]
gi\|558190055\|ref\|XP_006129229.1\|	2.650e-156	62.61	PREDICTED: dual specificity mitogen-activated prot...	[more]
gi\|1339053585\|ref\|XP_023715161.1\|	2.875e-156	68.97	dual specificity mitogen-activated protein kinase ...	[more]
gi\|591369443\|ref\|XP_007059554.1\|	5.160e-156	63.28	PREDICTED: dual specificity mitogen-activated prot...	[more]
gi\|504130436\|ref\|XP_004578017.1\|	8.220e-156	62.43	PREDICTED: dual specificity mitogen-activated prot...	[more]
gi\|1339039119\|ref\|XP_023725996.1\|	1.043e-155	65.38	dual specificity mitogen-activated protein kinase ...	[more]
gi\|556958571\|ref\|XP_005990160.1\|	2.047e-155	62.15	PREDICTED: dual specificity mitogen-activated prot...	[more]

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Alignments

The following features are aligned


Aligned Feature	Feature Type	Alignment Location
scaffold505_size153196	supercontig	scaffold505_size153196:68891..70841 -

Analyses

This gene is derived from or has results from the following analyses


Analysis Name	Date Performed
maker	2018-02-12 .496401
T. kinsejongensis vs L. Salmonis peptides	2018-04-19
T. kingejongensis peptided Blastp vs. SwissProt	2018-04-19
T. kingsejongensis proteins Blastp vs. NR	2018-05-15

Properties


Property Name	Value
Note	P:protein phosphorylation

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Species	Type
maker-scaffold505_size153196-snap-gene-0.25-mRNA-1	maker-scaffold505_size153196-snap-gene-0.25-mRNA-1	Tigriopus kingsejongensis	mRNA

Sequences

The following sequences are available for this feature:

gene from alignment at scaffold505_size153196:68891..70841-

gene from alignment at scaffold505_size153196:68891..70841-

Legend: mRNA

Hold the cursor over a type above to highlight its positions in the sequence below.

>maker-scaffold505_size153196-snap-gene-0.25 ID=maker-scaffold505_size153196-snap-gene-0.25|Name=dual specificity mitogen-activated protein kinase kinase 1 isoform x2|organism=Tigriopus kingsejongensis|type=gene|length=1951bp|location=Sequence derived from alignment at scaffold505_size153196:68891..70841- (Tigriopus kingsejongensis)
GGCCCCTGAACCAATCCGAGAGGCCGAGTGGAACAGCCGGACGACGACTG
CGAGCTTCACTCGCCCCCGGATCTAGTGCCACGCCCCGAGACCCGCCCTG
TGCGGCCCGTGGGCGGCTCGCTCCCTGAGTGCCATCGCCATGTCGGGGAA
AAAGTGCAAGAAGCCCCCGCCCCTGCCCCTGATCCTGCCCACCGACGAAC
CCCTGTCCCTGGGCGATGAGTAAGGCCGACTGGGCGACTGGGGTGGGCGT
GGCCGGGGGACCGGAGACTAATGGCTAGCCTCTCATTCTAGGCCGGATTC
GGCGGGCTTGAACCGCTCCACCACGTCGGTGCCGGACGTGGCCCTGCAGT
TGGCCGACGTGGCCCTCGCCGACGTGGACGACGAACAGCGCAAGCGACTC
GAGTTCTTCATCAACCAGAAGAAGCAGCTCGGCGAGCTCAAGGGCGACGA
GGACTTTGAGAAGATCAAAGAATTGGGCGCCGGCAATGGAGGTACGTACA
TGGACCGTCCTGGCGTGTCCCAATTGATCCGCTATGTTGGGGGCTAGGTG
TGGTCCACTGCGTGCGGCACAAGCCCACCGGGACGGTCATGGCCAAGAAG
ATGATCCACCTGGAGGTCAAGCCGGCCATCAAAAAGCAGATCGTGACCGA
GCTCAAGATCCTGCACGAGTGCAACTCGCCTTACATCGTGGGCTTCTACG
GGGCCTACCATAGCGAAGGTGAGATCAACATCTGCATGGAATACATGGAC
GGCGGATCCTTGGACGTGGTGTTGAAGAAGAAAGCCCGCATCCCGGAGCA
GTACTCGCGCAAAATCACCTATGCTGTCCTCCGGGGATTGAGCTATCTGC
GGGAAAACCACCGTATCATCCATCGTGACGTCAAGCCCAGCAACATCCTG
GTCAACAGTCAGGGCGAGATCAAGATTTGCGACTTTGGCGTGTCCGGTCA
GCTCATCGATTCCATGGCCAACTCGTTCGTCGGCACGCGCAGCTACATGT
CGCCCGAGCGATTGCAGGTGGGTGTTCATGCCTAATGCCGCCCTTCTTCT
CTGCCCGGTTGGACTGTCCGGATGGACCCTGATGGTCTTGACTTGCAGGG
CTCCCAATATTCCGTGGCCAGTGATCTCTGGTCGCTTGGTCTCTCCCTCT
TGGAAATCAGCTTGGGCATGTATCCCATCCCTCCGCCCGACGCTGCCTCC
TTGATTCGGATCTTTGGTCACGAGATCGCCGACGATCCCAGCATTTTGGC
CAACCCGAGGACCCCAAGAACCCCGAGATCACCCAACGTCCTGGGAGCCC
CGGCCTCCGGTGGTAAGTCGCCGCGGCCTGCTCTCTCGTGTCCAAGCTAA
TGGACGCCCACAACCTCTTTCCAGCCAAGCCCATGGCCATTTTCGAGCTC
CTGGAATACATTGTGAATCAGCCGCCGCCCAAACTTCCGTCGCGGGTGTT
TTCGGAGGAGATGCGAGATTTTGTCGATCGATGCCTGAAGAAGAACTTCA
AGGAGAGACCCGATCTAGCTACATTAATGGCAAGTTGAATTGGCCACATT
TGGCTATTGTTTGTTTTTGAACTTTGGGAATGACCACCAAGTCTCTTCTC
TCTCGTGCAGGATCATCCCTGGATGAAGGGTGTGGAGTCAGATAATGTGA
ATATCGCGGAATGGGTTCGAGGAATTTGTGAAATATCCACCCCACAATAA
ACCACCCAATCCTACACAGAATGACGCTTGGGTGCTGATTCCCCTGGTGG
CTCCCTCTTTACTTAATCCCCTGTGTCTTGGCCGTCTATCCATCCTGGAC
GTGATTTCAACCCACTGCTCCTTTAACATTATGAGATCCAGTGATGATGG
CCGCAACTAATGCATTTCTGGTGATTCAAACCCAAAAATTCAAATCTTCC
CTGGAAAGCCATCACCTCGAACCGAGATATTCGTGTAGATTCAGTCCCGG
G

Synonyms

The feature 'dual specificity mitogen-activated protein kinase kinase 1 isoform x2' has the following synonyms


Synonym
Tk06003

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