multidrug resistance-associated protein 5, maker-scaffold605_size125465-snap-gene-0.27 (gene) Tigriopus kingsejongensis
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Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of multidrug resistance-associated protein 5 vs. L. salmonis genes
Match: EMLSAG00000002221 (supercontig:LSalAtl2s:LSalAtl2s1420:21426:31801:1 gene:EMLSAG00000002221 transcript:EMLSAT00000002221 description:"maker-LSalAtl2s1420-augustus-gene-0.12") HSP 1 Score: 693.345 bits (1788), Expect = 0.000e+0 Identity = 423/1260 (33.57%), Postives = 675/1260 (53.57%), Query Frame = 0
Query: 11 LLVSQFFRAVTFGVNFVIGVHTAQRVLGALQYLAYSKLLRLAAPNEAAL--GQLMTFFTGDQERITEGVIVGTLFLGTPILFIMSASYATYLVGPLSLVGLLIILLFYPVMGIIATLTSKLRLRIVNVTDKRTTQMNEILNSIRLIKMYAWEKSFEDRVHKIRAHEIKELRKAAFLQSSFTSITPSVTIIATIVTF--FTLTASGYDLTAPEAFTVFSIFVSLQFTVGTLPYALKCLAEAKVSLVRLQKFMSLPEYMHPS--SRNFNPDDPKNLRIQIQNANLGWTKAPEWETEDEKKKSKVTNKKKKAEKGSKDEAEVLKPKYEELSYTPCLFDINLTVEEGSLIGVAGPIGAGKSSLLSAIMGEMKQLTGDFKIRGRMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKA-RGKTVLLVSHGMQFLEKCDSVIYVSNGKIIERGTHKELMEQTEG------QYLHMSTFDQ-----SHKASRTRGYSESLEQPTLDEKV----------DDRKGSLTKRH---------ASIVSGSADE-----TDQAKGAFT---------VEEGDVENAGWGVLYRYFQ--------ACGGLFIMFLLFLAILAFALARLFTSVWLQIWLDNG-------DGLEQERMDNMTLYNMTYSDSEIKGFVTHNPDLWFYQTIYFVNLAIMVVIGLIKGIVLAFQFLKGSSKLHDAMLHRVMRSPMKFFDTTPSGRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMVPFGVILVVFCVLDVIMNRGILETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQTCTFVPFVMRMKADFRARFNSVERVAEYATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEP-NGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSM 1203
L++S+FF + +V+G+ ++ + Y K LR+ + + G+++ + D ++I + + P ++ +GP L G+L+++L P G IA+ T L+ + D+R +NE++ I+++K+YAWE+SF D + +R+ E+K L +LQ+ + I + ++VTF F L++ L + +AF ++F L+F + LP + + A VS+ R+ KFM+ E + + PDD I ++ A L +WE++++K L D++L +E GSL+ V G +G+GKSSLLSAI+GEM +++G +RG +A +QQAW+ N +++ NIL Y+ ++Y ++ ACAL +DL++L GD TEIGE+G+NLSGGQKQRV+LARA+Y+ DIYLLDDPLSAVD+ V K I+ I + + KT ++V+HG+ +L D +I + +G++ E GT+KEL+ Q Q+L + ++ H + G +E LEQ T +++ D SL K + S+ S DE T Q + + VE G V+ W + Y + AC F+++ L L+ L ++ ++I + G D + Q+ MD Y Y Y + I+VV+G + + ++ + +LH+ ML +++SPM FFDTTP GRILNR KD+D LD MP L ++ + VV P F++P +I++ + + I + K+LE+ ++SP+ S ++G IR Y + S F + ++ + A +NRW R+++VG L + A +V+ + S+SP + GL+++ + +++RM ++ +VER+ EY T E+EAP I + KP WP G I+FK+ S RYR+ L VL +S+DI GGEK+GIVGRTGAGK+S ++ R+ IEP G+I+ID V I ++GLH LRS I +IPQDPVLF G+LR N+DP D+Y + I A+ SHLK I ++ L V G+N S+G++QLICL RALLR+ +VL+LDEATA+VD++TD LIQ TI+ F TV+T+AHRL+T+++Y +I+V+K+GE VE G+ ELL+++ F SM
Sbjct: 372 LVLSKFFYKM-----YVVGMKIKTSLISTI----YRKALRVPTSTKKNISTGEIVNLMSVDAQKIVDLMPYINTVWSAPFQITIAIYLLWQTLGPSVLAGVLVMILLIPFNGFIASRTKTLQTNQMKEKDERIKLLNEVVQGIKIVKLYAWEQSFLDIISNVRSKEVKILTHIGYLQAGNSFIWTCAPFLVSLVTFATFILSSPENVLDSEKAFVCLTLFNILRFPLSMLPMIIGSMVLAGVSIKRINKFMNSEEIDEEAVEKKTAYPDD--KFAINLEKACL------KWESDEDKN---------------------------------ILSDVSLDIEVGSLVAVVGTVGSGKSSLLSAILGEMDKVSGLITVRGSIAYGAQQAWVLNTSLKNNILFNKSYDGDKYTRIVEACALKSDLDMLPGGDETEIGEKGINLSGGQKQRVSLARAVYSGSDIYLLDDPLSAVDSHVGKHIYDNVISSSSGILKDKTRVMVTHGVTYLPFTDKIIVMKDGRVSEIGTYKELLRQKGAFAEFIVQFLSEANENEVNENIKHDIEESFGKNELLEQITKAKQIVRERSVSLNSGDLVTSLVKNNPTNSASGSTTSLKENSGDESTDNDTKQTRPTTSQTQQYQDEKVETGSVK---WNIYMHYVKNMSIILVVACSSCFVIYQA-LNTLSNVLLAWWSDAVMKIEVRTGLNDNRTLDEINQDIMDXQVYYLSIYGG-------------------YCLGQGIVVVMGF---VFMYLACMEAAQRLHNQMLESILKSPMSFFDTTPQGRILNRLGKDLDVLDSVMPMVLRGWISCFLGVLSSLIVVMVTTPVFIIPASLIIICYFFIQRIYVATSRQLKRLESSSRSPIXSFFSETVSGAATIRAYGQSSTFISESESKVDDNQKANFPATVSNRWLAVRLEVVGNLIVFTAALLAVLGRDSLSPGLVGLSVSYALAVTASLNWLVRMASEVETNIVAVERIQEY-TKAEKEAPWIIEDTKPDEDWPRKGEISFKNYSTRYREGLDYVLKNVSLDIEGGEKIGIVGRTGAGKSSFTLSMFRI--IEPVTGNIIIDGVDITKLGLHQLRSRITIIPQDPVLFSGSLRRNLDPLDEYNETNIMEAISHSHLKPFIDSLKDGLEYHVSEGGENLSLGQRQLICLARALLRRTRVLILDEATAAVDLETDNLIQKTIRSEFKDSTVITIAHRLNTIMDYSKILVLKNGERVEYGTVAELLADKKSQFYSM 1552 HSP 2 Score: 90.5077 bits (223), Expect = 2.320e-18 Identity = 132/555 (23.78%), Postives = 239/555 (43.06%), Query Frame = 0
Query: 681 FVTHNPDLW---FYQTIYFVNLAIMVVIGLIKGIVLAFQF-------LKGSSKLHDAMLHRVMRSPMKFFDTTPSGRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMVPFGVILVVFCVLDVIMNRGI------LETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFD--RDLNIHLSATSLYRYANRWFV-----FRMDIVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQ-TCTFVPFVMRMKADFRARFNSVERVAEYATDLEQEAPEYIPEKKPASSWPEHG-AITFKDVSLRYRQDLPL-VLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTAL-EKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKC----TVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMM 1204
F T+ +LW Y I F + + +VL+ F +K + L + + +R P +G I+N S D ++ MP+ +V QI++ ++ + P + V+ +L + N I L+T +++ K I L+ + GI I++ Y + F R + + Y A F+ F + +V T +L++ +V+ A L L N+ + + +P ++ S++R+ ++ +E E EKK A +P+ AI + L++ D +L+ +S+DI G V +VG G+GK+SL++ ++ G +DKV GL +R +IA Q + +L++N+ F++ D +T + E LK+ + + +G N S G+KQ + L RA+ + + LLD+ ++VD I + + S T + V H + + D+IIVMK G + EIG+ KELL + G F +
Sbjct: 346 FSTNQEELWKGILYAVILFAS-------STVGSLVLSKFFYKMYVVGMKIKTSLISTIYRKALRVPTSTKKNISTGEIVNLMSVDAQKIVDLMPYI-----NTVWSAPFQITIAIYLLWQTLGPSVLAGVLVMILLIPFNGFIASRTKTLQTNQMKE--KDERIKLLNEVVQGIKIVKLYAWEQSFLDIISNVRSKEVKILTHIGYLQAGNSFIWTCAPFLVSLVTFATFILSSPENVL---DSEKAFVCLTLFNILRFPLSMLPMII---GSMVLAGVSIKRINKFMN--SEEIDEEAVEKKTA--YPDDKFAINLEKACLKWESDEDKNILSDVSLDIEVGSLVAVVGTVGSGKSSLLSAIL--------GE--MDKVS----GLITVRGSIAYGAQQAWVLNTSLKNNI-LFNKSYDGDKYTRIVEACALKSDLDMLPGGDETEIGEKGINLSGGQKQRVSLARAVYSGSDIYLLDDPLSAVDSHVGKHIYDNVISSSSGILKDKTRVMVTHGVTYLPFTDKIIVMKDGRVSEIGTYKELLRQK-GAFAEFI 860
BLAST of multidrug resistance-associated protein 5 vs. L. salmonis genes
Match: EMLSAG00000008248 (supercontig:LSalAtl2s:LSalAtl2s498:229862:245360:1 gene:EMLSAG00000008248 transcript:EMLSAT00000008248 description:"maker-LSalAtl2s498-snap-gene-2.25") HSP 1 Score: 638.647 bits (1646), Expect = 0.000e+0 Identity = 402/1210 (33.22%), Postives = 623/1210 (51.49%), Query Frame = 0
Query: 49 LRLAAPNEAALGQLMTFFTGDQERITEGVIVGTLFLGTPILFIMSASYATYLVGPLSLVGLLIILLFYPVMGIIATLTSKLRLRIVNVTDKRTTQMNEILNSIRLIKMYAWEKSFEDRVHKIRAHEIKELRKAAFLQSSFTSITPSVTIIATIVTF--FTLTASGYDLTAPEAFTVFSIFVSLQFTVGTLPYALKCLAEAKVSLVRLQKFMSLPEYMHPSSRNFNPDDPKNLRIQIQNANLGWTKAPEWETEDEKKKSKVTNKKKKAEKGSKDEAEVLKPKYEELSYTPCLFDINLTVEEGSLIGVAGPIGAGKSSLLSAIMGEMKQLTGDFKIRGRMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLK-ARGKTVLLVSHGMQFLEKCDSVIYVSNGKIIERGTHKELMEQTEGQYL------------HMSTFDQSHKA-----SRTRGYSESLEQ--------------------PTLDEKVDDRKGSLTKRHA-----SIVSGSADETDQAKGAFTVEEGDVENAG--WGVLYRYFQACGGL--FIMFLLFLAILAFALARLFTSVWLQIWLDNGDGLEQERMDNMTLYNMTYSDSEIKGFVTHNPDLWFYQTIYFVNLAIMVVIGLIKGIVLAFQFLKGSSKLHDAMLHRVMRSPMKFFDTTPSGRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMVPFGVILVVFCVLDVIMNRGILETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLN-IHLSATSLYR--YANRWFVFRMDIVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQTCTFVPFVMRMKADFRARFNSVERVAEYATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPN-GSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMK 1205
L+ ++ + ++G+ D +R+ + + + +P+ I++ ++GP SL GL +++L P+ ++ K + DKR M++ILN I+++K+YAWE SF D V R EI L+K+A + + + + S + + +F + L LT AF ++F L+ + LP + ++KVSL R+ F+ N +D L I E + S + DE L DI+L +E+GSL+ + G +G+GKSSLLS I+GEM+ + G + G+ QQ W+ N T+R NIL G + K+ Y+ VI ACAL DL++L GDLTEIGERG+NLSGGQK RV+LAR + DIY+LDDPLSAVD V + +F I +Q + KT + V+HG FL + D +I + NG I E GT+++L+E+ G++ ++ DQ K T G SE LE+ LDE D+ S+ R +VS +E +EE +E+ G + YF+ G L F L + + F+L ++WL W + + + N L EI L F+Q+I+ + ++ + IG L S K+H +L V+R+P+ FFDT P GRILNRFSKD+D +PF + + I ++C P+F V ++ + ++ + K++E++++SP+ H + + GI IR + F D ++N I +A + ++RW R++ +G + ++ A FS+ +G+ P + GL+L+ T + ++ + D SVER+ EY ++ QEAP +P P +WPEHG I F + RYR+ L LVL I+ I GEK+GIVGRTGAGK+SL L R+ IEP+ GSI ID +I +GL LRS I +IPQDP+LF G+LR N+DPF+ + D IW ALE SHLK+ + + L +V G N SVG++QLICL RA+LRK ++L+LDEATA++D++TD LIQ+TI+ F TVLT+AHR++T+++ +RI+V+ +G I E P+ LL+N + +F S++
Sbjct: 387 LKSSSKKQMSVGETTNLMAIDSQRLMDFCLYIDMIWSSPLKIIIAMYLLWQVLGPASLAGLAVMILLIPINIVVGKKVKKFTAIQMQNKDKRIKLMDDILNGIKVLKLYAWEPSFIDAVTNFRVQEIGALKKSALINAVTSFMWTSAPFLVALASFTTYVLIDEKNILTPSTAFVSLTLFNLLRLPLNLLPMMIMKAIQSKVSLDRINLFL-------------NKEDLDLLAIS-----------------HESQGSHAVKMCNVSLSWETDEG------------LNTLEDIDLDIEKGSLVAIVGQVGSGKSSLLSGILGEMEIVRGSINVDGQTIYAPQQPWLQNETLRNNILFGKRFNKKLYRRVIDACALSPDLDMLPAGDLTEIGERGINLSGGQKARVSLARCTXNNGDIYILDDPLSAVDVHVGRHLFENVISSQTGLLKNKTRIFVTHGAIFLPQTDKIIVMKNGVISESGTYRDLIEKENGEFAQFLINYLVDEKENILKNDQDLKTIIKDLESTVGGSEELEKRLEAAQSDKSTALTDLIQGTKYLDENTSDQCSSIASRKGEDDLDEVVSNDLNER-------LIEEEKIESGGIKLNIYLNYFKRTGLLASFFGILFYFSYQGFSLG---ANLWLSKWSTDRAAINSTSIRNHYL--------EIYAI------LGFFQSIFTMLGSVTIAIGT----------LNASMKIHGKLLENVLRAPLSFFDTNPLGRILNRFSKDIDVAXTTLPFNIRMMIAQSFNVLGTIVIICIALPWFFVIILPAVICYALIQKFYISCARQVKRIESISRSPIYSHFAETLTGIPTIRAFGMVHHF---IDENVNKIDFNAKCYFPTVISSRWLAVRLETLGNILVIFVALFSITSRGTTDPGMVGLSLSYALSVTTILNMLITVSTDVETNMVSVERIKEYE-NIPQEAPYDLPNSDPPPNWPEHGVIKFDNYKTRYRKGLDLVLKGINCTIQKGEKIGIVGRTGAGKSSLTLALFRI--IEPSEGSIYIDGENIRFLGLGKLRSRITIIPQDPILFSGSLRMNLDPFEAFADRDIWIALEYSHLKSFVWNLGDGLNFSVLEGGRNLSVGQRQLICLARAILRKTQILVLDEATAAIDLETDDLIQSTIRSEFKDSTVLTIAHRINTIMDSNRIMVLDAGTIAEFDDPQNLLANPDSMFYSLVN 1514 HSP 2 Score: 76.2554 bits (186), Expect = 5.298e-14 Identity = 68/258 (26.36%), Postives = 113/258 (43.80%), Query Frame = 0
Query: 969 AITFKDVSLRYRQDLPL-VLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTD-FLIQATIKEA---FSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMKSVQMDHQASPVREAEE 1221
A+ +VSL + D L L I +DI G V IVG+ G+GK+SL++ ++ EI GSI +D I PQ P L TLR+N+ ++ ++ L + + G N S G+K + L R + +LD+ ++VDV L + I T + V H + D+IIVMK+G I E G+ ++L+ NG F + + +D + + ++ ++
Sbjct: 616 AVKMCNVSLSWETDEGLNTLEDIDLDIEKGSLVAIVGQVGSGKSSLLSGILGEMEI-VRGSINVDGQTIYA-------------PQQPWLQNETLRNNILFGKRFNKKLYRRVIDACALSPDLDMLPAGDLTEIGERGINLSGGQKARVSLARCTXNNGDIYILDDPLSAVDVHVGRHLFENVISSQTGLLKNKTRIFVTHGAIFLPQTDKIIVMKNGVISESGTYRDLIEKENGEFAQFLINYLVDEKENILKNDQD 859
BLAST of multidrug resistance-associated protein 5 vs. L. salmonis genes
Match: EMLSAG00000003611 (supercontig:LSalAtl2s:LSalAtl2s197:49356:53594:-1 gene:EMLSAG00000003611 transcript:EMLSAT00000003611 description:"augustus_masked-LSalAtl2s197-processed-gene-0.4") HSP 1 Score: 632.869 bits (1631), Expect = 0.000e+0 Identity = 406/1238 (32.79%), Postives = 634/1238 (51.21%), Query Frame = 0
Query: 10 VLLVSQFFRAVTFGVNFVIGVHTAQRVLGALQYLAYSKLLRLA--APNEAALGQLMTFFTGDQERITEGVIVGTLFLGTPILFIMSASYATYLVGPLSLVGLLIILLFYPVMGIIATLTSKLRLRIVNVTDKRTTQMNEILNSIRLIKMYAWEKSFEDRVHKIRAHEIKELRKAAFLQSSFTSITPSVTIIATIVTF--FTLTASGYDLTAPEAFTVFSIFVSLQFTVGTLPYALKCLAEAKVSLVRLQKFMSLPEYMHPSSR----NFNPDDPKNLRIQIQNANLGWTKAPEWETEDEKKKSKVTNKKKKAEKGSKDEAEVLKPKYEELSYTPCLFDINLTVEEGSLIGVAGPIGAGKSSLLSAIMGEMKQLTGDFKIRGRMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKA-RGKTVLLVSHGMQFLEKCDSVIYVSNGKIIERGTHKELMEQTEGQYLHMSTFDQSHKASRTRGYSESLEQPTLDEKVDDRKGSLTKRHASIVSGSADETDQAKGAFTVEEGDVENAGWGVLYRYFQACGGLFIMFLLFLAILAFALARLF---TSVWLQIWLDNGDGLEQERMDNMTLYNMTYSDSEIKGFVTHNPDLWFYQTIY-FVNLAIMVVIGLIKGIVLAFQFLKGSSKLHDAMLHRVMRSPMKFFDTTPSGRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMVPFGVILV-------------VFCVLDVIMNRGILETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQTCTFVPFVMRMKADFRARFNSVERVAEYA-TDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMKSVQMDHQASPVREAE 1220
+L++ F ++V F I + R+ +L L Y K L+L+ + ++G+++ + D RI + + TL +P ++S + +G + G I+L+ PV I++ K +++ + D RT +NE+L IR++K+YAWE S+ +++ IR EI L+KAA+L S I S I + +F F + LTA +AF S ++ + P+ + A VSL R+ + ++ E + N + I I++ N +W TED + L +INL ++ GSL + G +G+GKSSL+SAI+GEM + +G +I+G++A V Q++W+ N +++ NIL G Y++E Y V+ C L DL LL GD TEIGERG+NLSGGQ+QR++LARA+Y+D D+Y+ D+PLSA+D++V K +F + + KT LLV+HG+ +L + + G+II GT++EL+E+ Q + + + + T D V++ + A+I+ ET + W V Y Q+ G L FL I L +LF +S+WL+ W QE N T+ Y D Y +Y + + V I L+ V F LK S +H+ R+MR+P+ FFD+TP GRILNRFSKD+ +C ++L + + C ++ + + ++ V VF ++ I + K+L++VT+SP+ H S ++ G++ IR Y QS F ++ + ANRW R++ +G L I A ++ V P GL ++ + ++ R ++ +VER+ EYA D+E+E + K + +WP G + FK+ SLRY+ + LVL KI+ I GGE+VGIVGRTGAGK+SL L R+ E NG I+ID I+ +GLHDLR ++ VIPQ+P+LF GTLRSN+DP + ++D IW L HLK I ++ L ++ G N S G++QL+CL RALLR K+L+LDEATA+VD +TD IQ TI+ F CT+LT+AHRL T+++YD+I+V+ G ++E GSP EL N + VF SM+ + + ASP E E
Sbjct: 275 MLIIVSFLQSVLLAKYFEIVFLVSMRIRASLTSLVYRKCLKLSNSSRKNKSVGEIVNIMSVDVSRIADLMPFLTLLWSSPFQIVVSVIFMYNELGWAIIGGTGILLITIPVNAILSYFGKKFQMKQMKAKDNRTKILNEVLGGIRILKLYAWEPSYINKIEGIRGVEIGILKKAAWLTSFMGFIWSSTPFIVALASFATFVMVDDRNILTAEKAFVTQSYINKMKMPMAXFPFVIVXAISATVSLKRINQLLTSDELQKDAVERVPMKINQKIDQGDAIVIRDGNF------KWSTEDSEN---------------------------------TLSNINLRIKHGSLTAIVGTVGSGKSSLISAILGEMVKKSGKVRIKGQIAYVPQESWMQNTSLKNNILFGKPYDEEWYNQVLEYCCLTYDLSLLPAGDETEIGERGINLSGGQRQRISLARAIYSDADVYIFDNPLSALDSQVGKSVFNNVLNNNTGIIKDKTRLLVTHGISYLPHVHHIAVMLKGEIIHEGTYQELLEKKIIQTIEEEEEQEKDGVQENNINNYNNIPKTFDATVNNLE------KAAIIQKEGLETGRV--------------SWSVYKYYIQSIGFLGA----FLIIFNQMLNQLFGFGSSIWLEAW-------TQEDYGNATI--PKYRD--------------LYLGVYGALGIGQAVTIFLLSLSVAMFT-LKASKVIHNQTYDRIMRAPISFFDSTPQGRILNRFSKDIS------------ICDNILGSNIRQWLXC-LFXFLGIVILIVSVLPLFLLFALPTSLVFILIQNIYVASSRQLKRLQSVTRSPIYSHFSESLNGLSSIRAYGAQSKFILESINKIDTNQRCNYPSIIANRWLAMRLETIGNLCIFGXAILTMTNPELVGPGKVGLVISYALILTQNLNWLXRQTSEIETNIVAVERLKEYAGLDIEKE---WRLHKDTSYNWPSQGKVEFKNYSLRYKANSDLVLKKINFTIFGGERVGIVGRTGAGKSSLSVALFRIVE-AANGQILIDGKDISTLGLHDLRESLTVIPQEPLLFSGTLRSNLDPENAFSDHDIWNTLGSVHLKEYIRDLKDGLNHSISEGGLNLSSGQRQLMCLARALLRSCKILILDEATAAVDWETDEKIQETIRCYFPSCTILTIAHRLKTIIDYDKILVLDKGTVIEFGSPNELYMNSDSVFHSMINAAGITLTASPKNEIE 1408 HSP 2 Score: 65.855 bits (159), Expect = 6.936e-11 Identity = 116/536 (21.64%), Postives = 229/536 (42.72%), Query Frame = 0
Query: 700 AIMVVIGLIKGIVLAFQF---LKGSSKLHDAMLHRVMRSPMKFFDTTPS----GRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMVPFGVILVVFCVLDVIMNRG----ILETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFD--RDLNIHLSATSLYRYANRWFVFRMD--IVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQTCTFV----------PFVMRMKADFRARFNSVERVAEYAT--DLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYR-QDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNV---DPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVD------VKTDFLIQAT--IKEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNR 1196
++++++ ++ ++LA F S ++ ++ V R +K +++ G I+N S D+ + MPF T V+ I + + + G++L+ V ++ G + + K +N TK L+ + GI I++ Y + + + + R + I + + + + F++ IV + + A F +V ++ L F T +++ PFV+ S++R+ + T +L+++A E +P K + AI +D + ++ +D L+ I++ I G IVG G+GK+SL++ ++ G +V + G ++ IA +PQ+ + +L++N+ P+D+ Q+ LE L +S + G N S G++Q I L RA+ V + D +++D V + L T IK+ T L V H + + + I VM GEI+ G+ +ELL +
Sbjct: 274 SMLIIVSFLQSVLLAKYFEIVFLVSMRIRASLTSLVYRKCLKLSNSSRKNKSVGEIVNIMSVDVSRIADLMPFLTLLWSSPFQIVVSVIFMYNELGWAIIGGTGILLITIPVNAILSYFGKKFQMKQMKAKDNRTKI-----LNEVLGGIRILKLYAWEPSYINKIEGIRGVEIGILKKAAWLTSFMGFIWSSTPFIVALASF---ATFVMVDDRNI------LTAEKAFVTQSYINKMKMPMAXFPFVIVXAISATV---SLKRINQLLTSDELQKDAVERVP-MKINQKIDQGDAIVIRDGNFKWSTEDSENTLSNINLRIKHGSLTAIVGTVGSGKSSLISAIL--------GEMV------KKSGKVRIKGQIAYVPQESWMQNTSLKNNILFGKPYDEEWYNQV---LEYCCLTYDLSLLPAGDETEIGERGINLSGGQRQRISLARAIYSDADVYIFDNPLSALDSQVGKSVFNNVLNNNTGIIKDK----TRLLVTHGISYLPHVHHIAVMLKGEIIHEGTYQELLEKK 770
BLAST of multidrug resistance-associated protein 5 vs. L. salmonis genes
Match: EMLSAG00000011700 (supercontig:LSalAtl2s:LSalAtl2s812:79332:86643:-1 gene:EMLSAG00000011700 transcript:EMLSAT00000011700 description:"maker-LSalAtl2s812-augustus-gene-0.6") HSP 1 Score: 585.874 bits (1509), Expect = 0.000e+0 Identity = 328/870 (37.70%), Postives = 502/870 (57.70%), Query Frame = 0
Query: 339 DINLTVEEGSLIGVAGPIGAGKSSLLSAIMGEM---KQLTGDFKIRGRMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKARGKTVLLVSHGMQFLEKCDSVIYVSNGKIIERGTHKELMEQTEGQYLHMSTFDQSHKASRTRGYSESLEQPTLDEKVDDRKGSLTKRHASIVSGSADETDQAKGAFTVEEGDVENAGWGV-LYRYFQACGGLFIMFLLFLAILAFALARLFTSVWLQIWLDNGDGLEQERMDNMTLYNMTYSDSEIKGFVTHNPDLWFYQTIYFVNLAIMVVIGLIKGIVLAFQFLKGSSKLHDAMLHRVMRSPMKFFDTTPSGRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMVPFGVILVVFCVLDVIMNRGILETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQTCTFVPFVMRMKADFRARFNSVERVAEYATDLEQEAPEYIPEK-KPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSM 1203
DI++ V G+LI + GP+G+GKSSL+SA++GEM + T +I G +A Q AW+ N +V++NIL G + K Y V++AC+L++D+E +GD TEIGE+G+NLSGGQKQR++LARA+Y+ DIY LDDPL+ VD+ VAK +F E I + RGKT +LV+H + FL D + ++ +G+I E+GT+KELME+ S +H ++ S+S + EK+++ TK+ DE T+ G V G+ +Y YF + G+ L F + + +SVWL +W D +N D++++ IY + I ++L+ L S LH + ++++PM FFDTTP GRILNRF +D++ LD +M F + ++++ P F++P I VV+ V+ ++ + K+L +V SP+ H ++GI +R Y + F F+R L+ + A+RW R++++G I +A FSV+ + +++P GL +++ + + +V+RM +D +VER+ EY+ E EAP + E K SSWP G IT K++SL+YR+DL VL I++ I+ G+K+GIVGRTG+GK++L L RL E+ +G I ID V I ++GLH LRS + +IPQDP LF GTLR N+DPF + D ++ +L+ ++L+ + ++ L + G+N S+G++QLICL RALLRKNKVL++DEATA+VD +TD LIQ IK+ F TVLT+AHRL TV++Y +IIV+ SG I+E SPK LLS+ + F M
Sbjct: 1166 DISMDVNRGNLIAIIGPVGSGKSSLISALLGEMLFTSKGTNPVEIHGSVAYTPQNAWMQNVSVKDNILFGRKFNKNWYDEVLKACSLESDMEXFPSGDSTEIGEKGINLSGGQKQRISLARAVYSQSDIYFLDDPLAXVDSHVAKHLFEEVIGSNGLLRGKTRILVTHNLSFLHLVDEIYFLKDGEITEKGTYKELMEKN----CDFSELISNHANNKITNQSDS---EKVMEKINEEG---TKQPIETNFKIYDEE-------TLHTGQV-----GIRVYWYFLSKIGMLAGILAFSFFIISQILATGSSVWLSVWSD----------------------------AKNNTDIYYHLGIYAGLGVSNIFISTAGTLILSLSLLDASRILHGTLFQCIIKTPMSFFDTTPLGRILNRFGQDIEVLDTKMSFCIFGSMTGTFAYIATVTIISINVPIFIIPTLAIFVVYFVILIVSLSSSRQLKRLSSVATSPIYSHFGETLSGINTVRAYSLEKAFYSEFERRLDEYQKRNFPVIMADRWLGIRINLIGNFIIFASALFSVLSRDTITPGQLGLNVSSSLAITSILSWVIRMYSDLENNIVAVERIKEYSNK-ESEAPWELEEDLKLNSSWPLKGEITIKNLSLKYRKDLDWVLRDINVHISPGDKIGIVGRTGSGKSTLALALFRLLEVN-SGQITIDGVDIKKMGLHTLRSKLTIIPQDPTLFSGTLRLNLDPFGLFKDMELIESLKHAYLQDFLK--EDGLDKVIAENGENISLGQRQLICLARALLRKNKVLIMDEATAAVDSETDKLIQKAIKDNFRDSTVLTIAHRLQTVLDYSKIIVIDSGCIIEYDSPKNLLSDSSSTFYKM 1981 HSP 2 Score: 95.5153 bits (236), Expect = 6.080e-20 Identity = 69/267 (25.84%), Postives = 134/267 (50.19%), Query Frame = 0
Query: 1 LQYGWTLVLVLLVSQFFRAVTFGVNFVIGVHTAQRVLGALQYLAYSKLLRL-AAPNEAALGQLMTFFTGDQERITEGV-IVGTLFLGTPILFIMSASYATYLVGPLSLVGLLIILLFYPVMGIIATLTSKLRLRIVNVTDKRTTQMNEILNSIRLIKMYAWEKSFEDRVHKIRAHEIKELRKAA----FLQSSFTSITPSVTIIATIVTFFTLTASGYDLTAPEAFTVFSIFVSLQFTVGTLPYALKCLAEAKVSLVRLQKFMSLPE 261
L G L ++L ++ F V ++ ++ L Y K LR+ + ++ G+++ + D ++I + + ++ T++ G P+ I + +G +L G+L++ L P+ G IA +++ + D+R +MNEIL I++IK+YAWE SF + IR EIK L+ ++ F+ + +S T +++ T + + + L + + F S+F L+F + L + + +A A VSL R+ KF++ E
Sbjct: 865 LGQGIALSVILFGNKILGTFFIARYFFYMVTVGMKLKTSITSLIYRKALRIHSTRDDTTSGEIVNLMSVDVQKIVDLMPLLNTIWSG-PLQIIAAIYLLINTLGYSALAGVLVMFLLIPINGFIAVRMKNAQMKQMKKKDERVKKMNEILQGIKIIKLYAWESSFSKLISSIRFEEIKLLKLSSKYFGFMMLTISSTTFFISLF-TFIVYVVSDPENHILDSEKIFVSISLFNILRFPLNMLTHVIGGIASASVSLKRINKFLASEE 1129 HSP 3 Score: 82.8037 bits (203), Expect = 4.760e-16 Identity = 107/458 (23.36%), Postives = 203/458 (44.32%), Query Frame = 0
Query: 103 PLSLVGLLIILLFYPVMGIIATLTSKLRLRIVNV-TDKRTTQMNEILNSIRLIKMYAWEKSFEDRVHKIRAHEIKELRKAAFLQSSFTSITPSVTIIATIVTFFT--LTASGYDLTAPEAFTVFSIFVSLQFTVGTLPYALKCLAEAKVSLVRLQKFMSLPEYMHPSSRNFNPDDPKNLRIQIQNANLGWTKAPEWETEDEKKKSKVTNKKKKAEKGSKDEAEVLKPKY-EELSYTPCLFDINLTVEEGSLIGVAGPIGAGKSSLLSAIMGEMKQLTGDFKI-------------RGRMALVSQQAWIFNGTVRENI-LMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKARGKTVLLVSHGMQFLEKCDSVIYVSNGKIIERGTHKELMEQTEGQYLHM 542
P+ ++ L I + Y V+ I++ +S+ R+ +V T + E L+ I ++ Y+ EK+F + R E ++ + + I + +I + F + + D P + ++ SL T L + ++ ++ + ++V +++ + EY + S +AP WE E++ K + ++ K E K+ L KY ++L + L DIN+ + G IG+ G G+GKS+L A+ ++ +G I R ++ ++ Q +F+GT+R N+ G + E + + A D L +G I E G N+S GQ+Q + LARAL + ++D+ +AVD+ K I + + R TVL ++H +Q + +I + +G IIE + K L+ + + M
Sbjct: 1570 PIFIIPTLAIFVVYFVILIVSLSSSRQLKRLSSVATSPIYSHFGETLSGINTVRAYSLEKAFYSEFER-RLDEYQKRNFPVIMADRWLGI--RINLIGNFIIFASALFSVLSRDTITPGQLGL-NVSSSLAIT-SILSWVIRMYSDLENNIVAVER---IKEYSNKES-----------------------EAP-WELEEDLKLN--SSWPLKGEITIKN----LSLKYRKDLDWV--LRDINVHISPGDKIGIVGRTGSGKSTLALALFRLLEVNSGQITIDGVDIKKMGLHTLRSKLTIIPQDPTLFSGTLRLNLDPFGLFKDMELIESLKHAYLQDF---LKEDGLDKVIAENGENISLGQRQLICLARALLRKNKVLIMDEATAAVDSETDKLIQKA---IKDNFRDSTVLTIAHRLQTVLDYSKIIVIDSGCIIEYDSPKNLLSDSSSTFYKM 1981 HSP 4 Score: 71.2478 bits (173), Expect = 1.703e-12 Identity = 107/484 (22.11%), Postives = 201/484 (41.53%), Query Frame = 0
Query: 741 DTTPSGRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMVPFGVILVVFCVLDV-------IMNRGILETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQTCTF-----VPFVM--RMKADFRARFNSVERVAEYATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNK-ISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVK-TDFLIQATIKEA--FSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMKS 1206
D T SG I+N S D+ ++ MP + L + I ++ Y +LV+F ++ + + N + + KK K + ++ + GI II+ Y +S F K +I L + ++++F F M + T ++ +V+ S P L +F + + P M + + S++R+ ++ E E + S+ +H AI S + L K ISMD+ G + I+G G+GK+SL++ L+ G ++ + +H ++A PQ+ + +++ N+ ++ L+ L++ + + + + +G N S G+KQ I L RA+ ++ + LD+ A VD L + I T + V H L + D I +K GEI E G+ KEL+ +N F+ ++ +
Sbjct: 920 DDTTSGEIVNLMSVDVQKIVDLMPLLNT-IWSGPLQIIAAIYLLINTLGY--SALAGVLVMFLLIPINGFIAVRMKNAQMKQMKK-----KDERVKKMNEILQGIKIIKLYAWESSFSKLIS---SIRFEEIKLLKLSSKYFGFMMLTISSTTFFISLFTFIVYVVS-DPENHILDSEKIFVSISLFNILRFPLNMLTHVIGGIASASVSLKRINKFLASEELEEGILV-----RSNSHDHQAICIHPSSSFSWKGSSESLFKDISMDVNRGNLIAIIGPVGSGKSSLISALL--------GEMLFTSKGTNPVEIH---GSVAYTPQNAWMQNVSVKDNILFGRKFNKNWYDEVLKACSLESDMEXFPSGDSTEIGEKGINLSGGQKQRISLARAVYSQSDIYFLDDPLAXVDSHVAKHLFEEVIGSNGLLRGKTRILVTHNLSFLHLVDEIYFLKDGEITEKGTYKELME-KNCDFSELISN 1374
BLAST of multidrug resistance-associated protein 5 vs. L. salmonis genes
Match: EMLSAG00000001655 (supercontig:LSalAtl2s:LSalAtl2s128:1836948:1854487:1 gene:EMLSAG00000001655 transcript:EMLSAT00000001655 description:"augustus_masked-LSalAtl2s128-processed-gene-18.4") HSP 1 Score: 540.421 bits (1391), Expect = 1.808e-169 Identity = 360/1227 (29.34%), Postives = 599/1227 (48.82%), Query Frame = 0
Query: 1 LQYGWTLVLVLLVSQFFRAV-----TFGVNFVIGVHTAQRVLGAL--QYLAYSKLLRLAAPNEAALGQLMTFFTGDQERITEGVIVGTLFLGTPILFIMSASYATYLVGPLSLVGLLIILLFYPVMGIIATLTSKLRLRIVNVTDKRTTQMNEILNSIRLIKMYAWEKSFEDRVHKIRAHEIKELRKAAFLQSSFTSITPSVTIIATIVTFFTLTASGYDLTAPEAFTVFSIFVSLQFTVGTLPYALKCLAEAKVSLVRLQKFMSLP---------EYMHPSSRNFNPDDPKNLRIQIQNANLGWTKAPEWETEDEKKKSKVTNKKKKAEKGSKDEAEVLKPKYEELSYTPCLFDINLTVEEGSLIGVAGPIGAGKSSLLSAIMGEMKQLTGDFKIRGRM---ALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKARGKTVLLVSHGMQFLEKCDSVIYVSNGKI--IERGTHKELMEQTEGQYLHMSTFDQSHKASRTRGYSESLEQPTLDEKVDDRKGSLTKRHASIVSGSADETDQAKGAFTVEEGDVENAGWGVLYRYFQACGGLFIMFLLFLAILAFALARLFTSVWLQIWLDNGDGLEQERMDNMTLYNMTYSDSEIKGFVTHNPDLWFYQTIYFVNLAIMVVIGLIKGIVLAFQFLKGSSKLHDAMLHRVMRSPMKFFDTTPSGRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMVPFGVILVVFCVLDVIMNRGILETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQTCTFVPFVMRMKADFRARFNSVERVAEYATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKI-SGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMK 1205
L++G+ L VS F A+ F +N +G+ V+ +L Q L+ S+ A N+ + G+++ F + D +R+ F P +++ VG S VG+ +L P+ +IAT L +++ D R + EI+ IR+IK Y WE F D+ + R +EI L+ +L + + S +I ++ TF T +A G LTA + FT ++F L P+ + L EA VS+ RL +F+SLP EY +++ + K IQI A+ G+TK +T L +I+++++ +GV GP+G+GK++ L+AI+GE+++ +G +R + A V Q WI N ++R+NIL G +Y +Y VI+AC LD D + L GD T GE+G LSGGQK R+ LARA+Y D DIYL+DD S++D V K++ E +L LK KT +L +H Q++ + VI + +G+ +++ TH + S FD K +++++ S +E Q G + + +Y+QA G ++ + ++I +A T +WL W+ DN F + D Y +Y ++ LI+ + A+ + + +HD +L ++R+ + FFD+TP+GRILNRFS D +D +PF + ++ V + P+ ++ + + + + G + K++ +V+ SP+ H + + G+ IIR + F + + + A A+ W R+ ++G + + A SV+ SV + GLA++ + V+ + +VER +Y + +E+ Y +WP G + FKD+ LRY+ LP VLNK++ EK+GIVGRTGAGK+SL+ L RL+ +G I++D + I + L D R AVIPQDP +F GT+R N+DP+ Q++D ++W +++ S+L I S + L + G + S+G+KQL+CL RA++ KV+ +DEATASVD +TD LI+ +K AF+ TV+T+AHR+ TV+N DRI VM +G+I+E G P++L+ + N F +++
Sbjct: 344 LRWGYFYAFSLFVSTFLVAICNTQFNFKMN-ELGLKVRASVIQSLYKQTLSVSE----ANLNKYSRGEIINFMSIDVDRVVNFAPSFHAFWSLPFQMVVTLYLLHQQVGVSSFVGVGFAILMIPINKVIATKIGSLSGHMMSAKDDRVKIIAEIIEGIRVIKYYCWESFFTDKTNSHRNNEIYYLKWRKYLDAVCVYLWASTPVIISVSTFATYSALGNPLTAAKVFTSMALFAMLSGPFNAFPFVINGLIEANVSIKRLARFLSLPSINRIKYFTEYKDENTKASKEIETKIPDIQIMEASFGFTKD---------------------------------------CFT--LRNIDVSIKRQEFVGVLGPVGSGKTTFLNAILGELEKQSGKISVRDPLSGIAYVQQVPWIQNKSIRDNILFGEMYIHGKYTKVIKACCLDHDFKHLHRGDHTIAGEKGAALSGGQKARIALARAIYQDKDIYLIDDVFSSLDVNVGYKVYTEVMLNLLKR--KTRILCTHNPQYINDANIVIKIKDGEFESVKQSTHLVPTSTSPDFSYDTSMFD-------------------------------FKDNSNVIDDSVEEEMQETGV----------VAYRIYKKYWQAIGT-YLAPTILISIFLMQVASNTTDLWLSHWVST---------DN---------------FQNNTEDTDHYIYVYSGLAVFHTILTLIRAFLFAYGGIHAAKIIHDLLLGVLLRAKIYFFDSTPAGRILNRFSSDTYAIDDSLPFILNIFLSQIFGVFGRVLVCVYAVPWILIVLLPLGLFYYEIQCKYRPGSRDLKRISSVSLSPIYEHFNETVHGLKIIRASKASQRFLLENEELVECNQKARYAAFSASLWLEIRLQLIGSIVVFSIALISVINFESVDAGLVGLAVSYALGMTXRLAEVVVSFTETEKELVAVERAYDYIDRIYEES--YSGVLNMPYNWPNQGVVEFKDIRLRYKDHLPYVLNKVNFKTKPKEKIGIVGRTGAGKSSLIAALFRLSSFS-HGEIMVDGIRIRLLPLIDFRRQFAVIPQDPFIFSGTIRQNLDPYAQHSDQELWDSIKLSYLYNIIYSFGSSGLDTLIGDGGKSLSIGQKQLLCLARAIITSAKVVFIDEATASVDKETDRLIRNVLKTAFNDKTVITIAHRIETVLNSDRIFVMSNGQIIEEGKPEDLIKSPNSEFRKLIE 1453
BLAST of multidrug resistance-associated protein 5 vs. L. salmonis genes
Match: EMLSAG00000000752 (supercontig:LSalAtl2s:LSalAtl2s111:55855:93761:1 gene:EMLSAG00000000752 transcript:EMLSAT00000000752 description:"maker-LSalAtl2s111-augustus-gene-1.10") HSP 1 Score: 542.347 bits (1396), Expect = 5.498e-169 Identity = 377/1207 (31.23%), Postives = 606/1207 (50.21%), Query Frame = 0
Query: 26 FVIGVHTAQRVLGALQYLAYSKLLRL--AAPNEAALGQLMTFFTGDQERITEGVIVGTLFLGTPILFIMSASYATYLVGPLSLVGLLIILLFYPVMGIIATLTSKLRLRIVNVTDKRTTQMNEILNSIRLIKMYAWEKSFEDRVHKIRAHEIKELRKAAFLQSSFTSITPSVTIIATIVTFFTLTASGYDLTAPEAFTVFSIFVSLQFTVGTL-PYALKCLAEAKVSLVRLQKFMSLPEYMHPSSRNFNPDDPKNLRIQIQNANLGWTKAPEWETEDEKKKSKVTNKKKKAEKGSKDEAEVLKPKYEELSYTPCLFDINLTVEEGSLIGVAGPIGAGKSSLLSAIMGEMKQLTGDFKIRGRMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKARGKTVLLVSHGMQFLEKCDSVIYV-SNGKIIERGTHKELMEQTEG-QYLHMSTFDQ-----SHKASRTRGYSESL--EQPTLDEKVDDRKGSLTKRHASIVSGSADETD---QAKGAFTVEEGDVE-----NAGWGVLYRYFQACGGLF-IMFLLFLAILAFALARLFTSVWLQIWLDNGDGLEQERMDNMTLYNMTYSDSEIKGFVTHNPDLWFYQTIYFVNLAIMVVIGLIKGIVLAFQF----LKGSSKLHDAMLHRVMRSPMKFFDTTPSGRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMVPFGVILVVFCVLDVIMNRGILETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQTCTFVPFVMRMKADFRARFNSVERVAEYATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMKSV 1207
+ + + T ++ A + Y K L L A+ +++GQ++ + D R + PI FI +Y G ++ G +++ F + + SKLRL + TD R MNEIL+ I++IKMYAWE F V R + F + G ++ A + F +F +F +++ + P A+ +EA VS+ R+++F+ L E ++++ +I + L P E + K+ + S L +I+ +VE G L + GP+G GKS+++ +++GE G+ I+GR++ SQ+AWIF+G+VR+NILMG +RY+ VIR CAL+ D+ +GD T +GE+G++LSGGQK R+NLAR +YA DIY+LDDPLSAVD V +++F I Q KTV+LV+H +QFL+ +++I + S+G+I GT+++LM Q+ YL ++ ++ S S + E + ++ L + V R+ S + G + E D + KG+ + G E + + ++YF A GG F + + FL+++ L + + WL++W + D + + T Y Y D ++ +T + + F+ IY +++I L + Q ++ S LHD M +V + +FFD P+GRILNRFSKD+ D +P + S +F ++ P +V V+L++ + K+LE +T+SPV L+S++ G+T IR + + + + FD +IH S+ + NR+F F D++ L + + + + GL+L C + + +R A+ SVERVAEY DL +E + K SWP+ G I F +V+L+Y P VL ++ EP G I ID V+I + L D+R I++IPQDP+LF+GT+R N+DPFD+Y + IW ALE++ L +S + L V G+NFSVG++QL CL RA+LRKNKVL++DEATA+VD TD LIQ I+ F CTV T+AHRL+TV++ DRI+VM GEI E+G+P +LLS+ + +F M+ +
Sbjct: 480 WYLSLKTGMQLRIAASAIIYRKALTLSKASLGRSSIGQMVNLLSNDVNRFDNSTVFLQYLWVAPIQFICVMLITSYFAGIEAVAGGALLIFFIFFQTYMGKMFSKLRLMTASKTDIRIQIMNEILDGIKVIKMYAWETPFVQLVTNARNR------------------------FVLLPVFLLMVLFGVEINAQKIFLIFGLFDAIKLPLTHFFPSAISASSEALVSMKRIEEFLLLNEL-------------RDVQSKINHVILPGRYEP-----------------------LTVEVTKISGKWLDSSNEFTLKNISFSVEIGELCAIIGPVGCGKSTIIQSLLGEFPVSYGEINIKGRISYASQEAWIFSGSVRQNILMGKPLIDKRYREVIRVCALEHDVREWPDGDYTFVGEKGISLSGGQKSRINLARCVYASADIYILDDPLSAVDPHVGQQLFDTCI--QKFLSDKTVILVTHQLQFLKNANNIILLNSDGEIEASGTYEKLMSQSGFVTYLEATSEEEDSDLLSDVLSDVKSDGEYMRSQKKKLKKGVRSRRSSTSLLVPVPYIGGSTERDTFPEEKGSQEWKMGSKETIIEGSVSLSLYHKYFVAGGGFFKFLCVYFLSLITHTLF-VVSDWWLRLWTNAADARKLGPLPP-TFYFSEYQDMTLQ--ITADFQVDFFNFIYCSIYLSLIIILLFSAQLSVRQLFMSCMRSSQTLHDRMFEKVAFTNSRFFDLNPNGRILNRFSKDIGSXDELLP--PALLSGSGIFI-----LISMTNPLIVVGIVVLLLILLTIRKYYLNASRAVKRLEGITRSPVFSQLASSLDGLTTIRSMKIEEMLIEEFDYLQDIHTSSYYSFLVVNRFFAFCGDLMLSLFTASMVSMFLFYNRDATGGDVGLSLTLSLALCGMIQWGLRQSAEVENFMTSVERVAEYG-DLPKEKG-LKGDIKLDPSWPDKGVIEFSNVNLKYDGTTPYVLKGLT--------------------------------EPEGKIFIDGVNICRLSLQDVRKKISIIPQDPLLFKGTIRKNLDPFDEYGELAIWHALEQAKLSVAVSELEGGLETEVSEGGNNFSVGQRQLFCLARAILRKNKVLIMDEATANVDPMTDSLIQEAIRTEFKDCTVFTIAHRLYTVMDSDRILVMSDGEIKELGAPLDLLSDPSNIFYQMVNQL 1579 HSP 2 Score: 223.402 bits (568), Expect = 2.437e-59 Identity = 121/305 (39.67%), Postives = 176/305 (57.70%), Query Frame = 0
Query: 924 MRMKADFRARFNSVERVAEYATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMKSVQ------MDHQASPVREAEEE 1222
+R A+ SVERV EY +++ E + P SWP+ G + F +VS+RY Q P VL ++ EK+GI+GRTGAGK+S+++ L RL E P G I ID + I ++GL D+R I++IPQDP+LF G++R N+DPF+++TD QIW ALE++ L + + L V G NFSVG++QL CL A+LR+NKVL++DEATA+VD TD LIQ I++ F CT E G+PK+LL + N + + M+ + + H AS + ++ EE
Sbjct: 6 LRQSAEVENFMTSVERVVEYGELPKEKGLESDIKLDP--SWPDKGVVEFSNVSMRYSQHQPNVLKGLNFKTNSFEKIGIIGRTGAGKSSIISALFRLAE--PEGEIFIDGLDICKVGLLDIRKKISIIPQDPILFNGSIRKNLDPFNEFTDVQIWNALEQAKLYDIVVDLGHGLDSVVLEFGSNFSVGQRQLFCLAXAILRRNKVLIMDEATANVDPFTDSLIQEAIRKEFKDCT--------------------------EFGTPKDLLKDPNNLLSRMVAQSEPNTAHTLRHLASGIIDSIEE 280 HSP 3 Score: 66.2402 bits (160), Expect = 4.997e-11 Identity = 46/185 (24.86%), Postives = 87/185 (47.03%), Query Frame = 0
Query: 380 IRGRMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKARGKTVLLVSHGMQFLEKCDSVIYVSNGKIIERGTHKELMEQTEGQYLHMSTFDQSHKASRTRGYSESLEQP 564
+R +++++ Q +F GT+R+N+ Y + + L + L G TE+ E G N S GQ+Q LARA+ + ++D+ + VD + + +E I T+ K TV ++H + + D ++ +S+G+I E G +L+ + M A R + ++ L+ P
Sbjct: 1416 VRKKISIIPQDPLLFKGTIRKNLDPFDEYGELAIWHALEQAKLSVAVSELEGGLETEVSEGGNNFSVGQRQLFCLARAILRKNKVLIMDEATANVDP-MTDSLIQEAIRTEFK--DCTVFTIAHRLYTVMDSDRILVMSDGEIKELGAPLDLLSDPSNIFYQMVNQLGPSAAERLKKIAQGLQSP 1597
BLAST of multidrug resistance-associated protein 5 vs. L. salmonis genes
Match: EMLSAG00000000090 (supercontig:LSalAtl2s:LSalAtl2s1014:9799:23913:-1 gene:EMLSAG00000000090 transcript:EMLSAT00000000090 description:"maker-LSalAtl2s1014-snap-gene-0.6") HSP 1 Score: 317.005 bits (811), Expect = 1.525e-92 Identity = 260/994 (26.16%), Postives = 461/994 (46.38%), Query Frame = 0
Query: 236 LPYALKCLAEAKVSLVRLQKFMSLPEYMHPSSRNFN--PDDPKNLRIQIQNANLGWTKAPEWETEDEKKKSKVTNKKKKAEKGSKDEAEVLKPKYEELSYTPCLFDINLTVEEGSLIGVAGPIGAGKSSLLSAIMGEMKQL-TGDFKIRGRMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKARGKTVLLVSHGMQFLEKCDSVIYVSNGKIIERGTHKELMEQTEGQYLHMSTFDQSHKASRTRGYSESLEQPTLDEKVDDRKGSLTKRHASIVSGSADETDQAKGAFTVEEGDVENAGWGVLYRYFQACGGLFIMFLLFLAILAFALARLFTSVWLQIWLDNGDGLEQERMDNMTLYNMTYSDSEIKGFVTHNPDLWFYQTIYFVNLAIMVVIGLIKGIVLAFQFLKGSSKLHDAMLHRVMRSPMKFFDTTPSGRILNRFSKDMDELDVRMP-FFTEFVCQSVLFCVTQ-ISVVCF-VYPYFMV-PFGVILVVFCVLDVIMNRGILETK--KLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGS--------VSPAIAGLALANVFQTCTFVPFVMRMKADFRARFNSVERVAEYATDLEQEA-----PEYIPE--KKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMK 1205
LP + L++ VS+ R+ +++ E S +F+ P IQ+Q+ N S D+ ++LK +IN + G L V G +G+GKS LL+A+ GE+ Q G I + V+Q W+ + T+R+NI G Y +YQ V+ C L D + + GDLT + G LSGGQ+QR+ ARA+Y + +YL+DDPLSA D+ + +IF I + + KT LL+++ + D +I + NG + E+ + +E + +F+ + K+++ +G S +P D + H ++ + D ++ K F+ LY+Y+ G + F+ +A++ + +++ F V ++WL L +++ ++ D+ V + W YF+++ +++ + LK SS HD +L +V +P+ FF +TP G I+NRFSKDMDE D+ +P F Q+V T I+++ F + +F+V P G+I + ++ +R + T KL V K H SA+ G T IR Y +S + ++ H S + + + R+ ++ I + A V F +S + L ++F + F+ + S+ER+ E + Q+ P I K+P + + I F+D S +Y + ++++ GEKVG+VGRTG+GK+SL+ L L E+E G I ID V ++ ++R D LF+G++R N+DP D++TD IW+ L+++ +K L ++ G N S+ LI ++DEA +++ ++++ I T FS T+ +AHR+ ++ D+I+V+++G I E G+P+ L+ ++ +F SM++
Sbjct: 8 LPSCISALSQGIVSIKRIDSYLNREEVDSVKSNDFSKSPRPEDGYSIQVQDCNY-----------------------------SIDKLKLLK-------------NINFSTRVGELTAVVGKVGSGKSCLLAALCGELNQRGKGSSLINKDLVYVTQNIWLKSATIRDNITFGQPYNSSQYQKVVSLCQLGQDFKDMYRGDLTYLASNGSTLSGGQRQRIGFARAIYQNAQVYLMDDPLSACDSNLKAQIFHNTIGPKGFLQKKTRLLITNQSSLIPLMDRIIVIQNGTVEEKDSAEE-----------VKSFEIAKKSTKKQG---SFHEPPKDNYL----------HPAL--DNYDIIERRKIPFS-------------LYKYYVLNLGT-VPFI--IALVGYLISQCF-DVCSKLWLSRWTNLSSTNINDTNYRHIYNEDTRNMYIVVYGILGWCQSLAYFLSV-----------LLINSRSLKASSHFHDVILRKVFGAPLNFFWSTPKGTIINRFSKDMDEADMFLPNTLKNFAYQAVKILGTLIIALIAFPITAFFIVCPLGLIFIEVVKSYLMASRFLKRTSATKLAMVLK----HFGDSAVHGGTTIRCYGVESDYIDEHMSLIDEHQSVSLMEIISEAXLFLRLQLIAGTFIGILATALVFFPSEGNSSSLSALSLTSSLTVLQDIFLFTRYAAFIEKAMV-------SIERIKECEDLIPQDPSSGLLPSIITNGSKRPKNHQSRY-YIQFEDFSGKYSSLKNASIKNFTLNVRLGEKVGVVGRTGSGKSSLILALSGLLEVE-KGKIFIDGVDMSSGTARNIRKKDIT---DAALFKGSIRYNLDPDDRFTDEYIWSVLDEAQMKEFFVQLPGGLDFSLKENGSNISLAGSNLI-------------IMDEAXSAMTLESEERILNTYFSRFSSSTIFVIAHRIQPLLACDKILVLENGTIAEFGNPESLIKSQKSIFKSMLR 876
BLAST of multidrug resistance-associated protein 5 vs. L. salmonis genes
Match: EMLSAG00000000741 (supercontig:LSalAtl2s:LSalAtl2s111:116041:261433:1 gene:EMLSAG00000000741 transcript:EMLSAT00000000741 description:"maker-LSalAtl2s111-snap-gene-2.14") HSP 1 Score: 321.627 bits (823), Expect = 1.256e-90 Identity = 245/825 (29.70%), Postives = 406/825 (49.21%), Query Frame = 0
Query: 3 YGWTLVLVLLVSQFFRAVTFGVNFVIGVHTAQRVLGALQYLAYSKLLRL--AAPNEAALGQLMTFFTGDQERITEGVIVGTLFLGTPILFIMSASYATYLVGPLSLVGLLIILLFYPVMGIIATLTSKLRLRIVNVTDKRTTQMNEILNSIRLIKMYAWEKSFEDRVHKIRAHEIKELRKAAFLQSSFTSITPSVTIIATIVTFFTLTASGYDLTAPEAFTVFSIFVSLQFTVGTL-PYALKCLAEAKVSLVRLQKFMSLPEYMH-PSSRNFNPD-DPK-NLRIQIQNANLGWTKAPEWETEDEKKKSKVTNKKKKAEKGSKDEAEVLKPKYEELSYTPCLFDINLTVEEGSLIGVAGPIGAGKSSLLSAIMGEMKQLTGDFKIRGRMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKARGKTVLLVSHGMQFLEKCDSVIYV-SNGKIIERGT-HKELMEQTEGQYLHMSTFDQSHKASRTRGYSESLEQPTLDEKVDDRKGSLTKRHASIVS-GSADETDQAKGAFTVEEGDVENAGW---------------GVLYRYFQACGGLFIMFLLFLAILAFALARLFTSVWLQIWLDNGDGLEQERMDNMTLYNMTYSDSEIKGFVTHNPDLW--FYQTIYFVNLAIMVV---IGLIKGIVLAFQFLKGSSKLHDAMLHRVMRSPMKFFDTTPSGRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMVPFGVI 798
Y W+ VL++ S + F V R+ A L Y K L+L A+ ++++GQ++ + D R V+ P+ FI+ + Y+VG S+ G I+L+F P+ I S+LR+ I TDKR MNEI+ +++IKMYAWE F + V++ R EI+ ++K ++ + + + ++ FF + +++ F +F +F +++ ++ P + +EA VS R+Q F+ L E SS P+ P+ +LRI+++N + WT E +D+ L +++ V + L + GP+G+GKS++L A++GE +GD I G+++ SQ+ WIF+GT+R+NIL+GA +RY V++ C+L+ DLE + D T +GE+GV LSGGQK R+NLAR++Y++ D+YLLDDPLSAVD+ V + ++ E I L KTV+LV+H +Q+L ++I + + G+I ++GT +K LM + + ++F + + + E E +K + + + +R +S+ S GS D +E D+ N G + +YF A GG +I F ++ + L + T WL+ W + D R +N Y S + GF DL+ Y IYF + +++ I + K ++L LK S LH M +V+ + FFD P GRILNRFSKD+ LD +P L V ++ P ++P G+I
Sbjct: 141 YIWSAVLIM--SGVLYVFSHHWYFFGVVQVGMRIRIACSALLYKKSLKLSKASIGKSSVGQMVNLLSNDVNRYDLCVLFIHYLWVAPLQFILVSIITWYMVGISSMCGGAILLVFIPLQTWIGKQFSRLRILIAGKTDKRIRVMNEIIEGMKVIKMYAWEYPFMEVVNETRRDEIQTIKKTYEYKAFNLGFFFTSSRVVLLLIFFLMIIGNEVISSKNIFLIFGLFNTVRLSLTLFFPNTISMTSEALVSTDRIQNFLLLEEIGDICSSMKHEPEVRPEVSLRIEMKNVSGKWTSN---EKDDD------------------------------------LRNVSFQVHKRELTAIIGPVGSGKSTILQALLGEFPVSSGDISIYGKISYASQEPWIFSGTIRQNILLGASMNHKRYLKVLKVCSLEHDLESWPDRDHTFVGEKGVALSGGQKARINLARSVYSEADVYLLDDPLSAVDSHVGRHLYEECIKNYLSR--KTVILVTHQIQYLGDASNIILLNTKGEIEDQGTLNKLLMSERD-----FTSFLVAQEEETDSIFDED-ELALTPKKSLNIENYMRRRQSSVSSIGSRATIDTN----AMEYNDIPNEGRRTQTTESKVKGSISVALYKKYFYAGGGKWIFFFVYGLNILSQLLFVSTDWWLKQWTNAADA----RTNN---YANASSFEILPGF---QIDLFNSIYYGIYFALVGALIICSQISIRKFLILC---LKSSKNLHLEMFQKVIFTKPAFFDVNPVGRILNRFSKDIGSLDXLLPLALSDTSLIFLNAVGMFGLIISTEPKVLIPLGLI 899 HSP 2 Score: 298.13 bits (762), Expect = 5.310e-83 Identity = 234/788 (29.70%), Postives = 386/788 (48.98%), Query Frame = 0
Query: 236 LPYALKCLAEAKVSLVRLQKFMSLPEYMH-PSSRNFNPD--DPKNLRIQIQNANLGWTKAPEWETEDEKKKSKVTNKKKKAEKGSKDEAEVLKPKYEELSYTPCLFDINLTVEEGSLIGVAGPIGAGKSSLLSAIMGEMKQLTGDFKIRGRMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKARGKTVLLVSHGMQFLEKCDSVIYV-SNGKIIERGT-HKELMEQTEGQYLHMSTFDQS----HKASRTRGYSESLEQPTLDEKVDDRKGSLTKRHASIVSGSADETD---QAKGAFTVEEGDVENAGWGVLYRYFQACGGLFIMFLLFLAILAFALARLFTSVWLQIWLDNGDGLEQ-ERMDNMTLYNMTYSDSE----IKGFVTHNPDLW--FYQTIYFVNLAIMVVIGLIKGIVLAFQFLKGSSKLHDAMLHRVMRSPMKFFDTTPSGRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMVPFGVILVVFCVLDVIMNRGILETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQTCTFVPFVMRMKADFRARFNSVERVAEYATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRY-RQDLPLVLNKISMDIAGGEKVGIV 1003
P + +EA VS R+Q F+ L E SS P+ ++LRI+++N + WT E +D+ L +++ V + L + GP+G+GKS++L A++GE +GD I G+++ SQ+ WIF+GT+R+NIL+GA +RY V++ C+LD DLE + D T +GE+GV LSGGQK R+NLAR++Y++ D+YLLDDPLSAVD+ V + ++ E I L KTV+LV+H +Q+L + +++I + + G+ +GT +K LM + + + ++ +++ HK +SL + S+ R A+I + + D + + T E + + +YF A GG ++ F ++ ++ L + T W + W + D ++ + N + +Y+++ + GF DL+ Y IYF + +++ I F LK S LH M +V+ + FFD P GRILNRFSKD+ LD +P L V ++ P ++P IL++ L K+LE +TKSPVI LS+ + GI+ IR + ++ F F +IH +A ++ R+F F +D G+++I + A + +V G++L+ + + +R A+ SVERVAEY DL E +KK SWP G I F +V L+Y Q P +L ++ I EK+ ++
Sbjct: 1154 FPNTISMTSEALVSTDRIQNFLLLEEIGDICSSMKHEPEVRPEESLRIEMKNVSGKWTSN---EKDDD------------------------------------LRNVSFQVHKRELTAIIGPVGSGKSTILQALLGEFPVSSGDISIYGKISYASQEPWIFSGTIRQNILLGAPMNHKRYLKVLKVCSLDHDLESWPDRDHTFVGEKGVALSGGQKARINLARSVYSEGDVYLLDDPLSAVDSHVGRYLYEECIKKYLSR--KTVILVTHQIQYLREANNIILLNTKGETEAQGTLNKLLMSERDFKPFLVAQEEETDSIFHKNELALTPRKSLNIENYMRRRQSSVSSIGSR-ATIDTNVMEYNDIPNEGRRTQTTESKVKGSISVALYKKYFYADGGKWMFFFVYGLNISSQLIFVMTDWWXKQWTNAADARKKFGDIRNQKHFFSSYANTSSFEILPGF---QIDLFNSIYYGIYFALVGALIICSQISVRKFIFLCLKSSRNLHSEMFQKVIFTKPAFFDVNPVGRILNRFSKDIGALDDLLPIALSDTNLIFLNAVGMSGLIISTEPKILIPLLAILIILLALRKYYLNASRSVKRLEGITKSPVISQLSTTLNGISTIRASKLENNFASEFHYLQDIHTAAFFSFQSVTRFFGFWVD--GIVSINVXATVVIFVFFNVKGGDIGISLSLSVLMARXIQWGLRQSAEVENYMTSVERVAEYG-DLPSEK-RLTSDKKIDPSWPNKGVIKFHNVKLKYDDQGGPYILKGLTFTINSFEKITLI 1892 HSP 3 Score: 70.0922 bits (170), Expect = 4.203e-12 Identity = 106/477 (22.22%), Postives = 198/477 (41.51%), Query Frame = 0
Query: 746 GRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMVPFGVILVVFCVLDVIMNRGILETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFD---RDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQTCT-----FVPFVMRMKA------DFRARFNSVERVAEYATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRY-RQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTD-FLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKS-GEIVEIGS-PKELLSNRNGVFTSMM 1204
G+++N S D++ D+ + F + F + I + ++ + G IL+VF L + + + L I ++ + G+ +I+ Y + F + + RD + T Y+ N F F V +L I F ++ V + + +F T F P + M + D F +E + + + ++ E PE +P S I K+VS ++ + L +S + E I+G G+GK++++ L+ G + I+ G I+ Q+P +F GT+R N+ + L+ L+ + ++ V +G S G+K I L R++ + V LLD+ ++VD L + IK S+ TV+ V H++ + + II++ + GEI + G+ K L+S R+ FTS +
Sbjct: 198 GQMVNLLSNDVNRYDLCVLFIHYLWVAPLQFILVSI-ITWYMVGISSMCGGAILLVFIPLQTWIGKQFSRLRILIAGKTDKRIRVMNEIIEGMKVIKMYAWEYPFMEVVNETRRDEIQTIKKTYEYKAFNLGFFFTSSRVVLLLIF----FLMIIGNEVISSKNIFLIFGLFNTVRLSLTLFFPNTISMTSEALVSTDRIQNFLLLEEIGDICSSMKHE-----PEVRPEVSL----RIEMKNVSGKWTSNEKDDDLRNVSFQVHKRELTAIIGPVGSGKSTILQALL--------GEFPVSSGDISIYG------KISYASQEPWIFSGTIRQNILLGASMNHKRYLKVLKVCSLEHDLESWPDRDHTFVGEKGVALSGGQKARINLARSVYSEADVYLLDDPLSAVDSHVGRHLYEECIKNYLSRKTVILVTHQIQYLGDASNIILLNTKGEIEDQGTLNKLLMSERD--FTSFL 644 HSP 4 Score: 62.7734 bits (151), Expect = 7.002e-10 Identity = 68/292 (23.29%), Postives = 125/292 (42.81%), Query Frame = 0
Query: 905 IAGLALANVFQTCTFVPFVMRMKADFRARFNSVERVAEYATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRY-RQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTD-FLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKS-GEIVEIGSPKELL 1193
I G++L F + + D F +E + + + ++ E PE PE E I K+VS ++ + L +S + E I+G G+GK++++ L+ G + I+ G I+ Q+P +F GT+R N+ + L+ L + ++ V +G S G+K I L R++ + V LLD+ ++VD +L + IK+ S+ TV+ V H++ + + II++ + GE G+ +LL
Sbjct: 1145 IEGISLTLFFPNTISMTSEALVSTDRIQNFLLLEEIGDICSSMKHE-PEVRPE--------ESLRIEMKNVSGKWTSNEKDDDLRNVSFQVHKRELTAIIGPVGSGKSTILQALL--------GEFPVSSGDISIYG------KISYASQEPWIFSGTIRQNILLGAPMNHKRYLKVLKVCSLDHDLESWPDRDHTFVGEKGVALSGGQKARINLARSVYSEGDVYLLDDPLSAVDSHVGRYLYEECIKKYLSRKTVILVTHQIQYLREANNIILLNTKGETEAQGTLNKLL 1413 HSP 5 Score: 62.003 bits (149), Expect = 1.212e-9 Identity = 47/151 (31.13%), Postives = 72/151 (47.68%), Query Frame = 0
Query: 3 YGWTLVLVLLVSQFFRAVTFGVNFVIGVHTAQRVLGALQYLAYSKLLRLAAPNEAALGQLMTFFTGDQERITEGVIVGTLFLGTPILFIMSASYATYLVGPLSLVGLLIILLFYPVMGIIATLTSKLRLRIVNVTDKRTTQMNEILNSIRL 153
Y W+ VL++ GV +V H G +Q L SK A+ ++++GQ++ + D R V+ P+ FI+ + A Y+VG S+ G I+L+F P+ I S+LR+ I TDKR MNEI+ I L
Sbjct: 1016 YIWSAVLIMS----------GVLYVFSHH--WHFFGMVQSLKLSK----ASIGKSSVGQMVNLLSNDVNRYDLCVLFLHYLWVAPLQFILVSMIAWYMVGISSMCGGAILLVFIPLQIWIGKQLSRLRILIAGKTDKRIRVMNEIIEGISL 1150
BLAST of multidrug resistance-associated protein 5 vs. L. salmonis genes
Match: EMLSAG00000002016 (supercontig:LSalAtl2s:LSalAtl2s1361:43077:48755:-1 gene:EMLSAG00000002016 transcript:EMLSAT00000002016 description:"augustus_masked-LSalAtl2s1361-processed-gene-0.2") HSP 1 Score: 272.707 bits (696), Expect = 9.370e-75 Identity = 181/655 (27.63%), Postives = 327/655 (49.92%), Query Frame = 0
Query: 594 QAKGAFTVEEGDVENAGWGVLYRYFQACGGLFIMFLLFLAILAFAL--ARLFTSVWLQIWLDNGDGLEQERMDNMTLYNMTYSDSEIKGFVTHNPDLWFYQTIYFVNLAIMVVIGLIKGIVLAFQFLKGSSKLHDAMLHRVMRSPMKFFDTTPSGRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMVPFGVILVVFCVLDVIMNRGILETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVF--KGS--VSPAIAGLALANVFQTCTFVPFVMRMKADFRARFNSVERVAEY-----------------ATDLEQEAPEYIPEKKPASSWPEHGA---------------ITFKDV----SLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMKS 1206
+++G + E + + GVL YF+A GG+F+ F IL+F L +++ L+ W +E++ D + Y FY ++ + + I V LI ++ A + +KLH+ M+ +M P++ F+ P GRI+NR S D+ +D ++P + + C+ ++ P F++ ++ ++ L R E ++L+++T++PV+ H S ++G+ +R + Q+ F ++ + SA + + RW +D G + + L+ ++ F KG S A GL++ ++ +V++ A+ N+VERV EY A+ + ++ + E I F V S YR+ LP + S++I +KVGI GR+G+GK++L+ ++RL+ + GSI I+ ++I I L LR + IPQD VLF GT+RSN+DP + ++D IW+ L+K+ + + L V GDNFS+G++Q + + +ALLR+ +V++LDE+T+++D + + T+ EAF T+++VAHRL +V Y+R++VM G I+E G+PKELL G F+++ ++
Sbjct: 1263 KSQGGQSHENREYGSIDIGVLTVYFKA-GGIFLAG--FFVILSFVLQSVKVYMDFLLRDW-----SMEEKNSDKLIAY------------------FSFYGSLSVIVILISCVANLIGQLIGA----RARTKLHNDMIQNIMYCPLELFEAFPIGRIINRISHDIFIVDQKIPPCIQRLIMLSFVCIAALAXNSIQSPVFLIFALPMISIYWWLXHFYRRSSRELQRLDSITRAPVLSHFSDTLSGLITVRAFGEQTRFINELCEKVDTNTSAFLILQSGCRWLGVYLDAAGAIFVFLSILVNLFFPRKGREVTSSASIGLSVNYSLLVPIYLAWVVKFAANIENYMNAVERVLEYTHFPSEEEDFSEFQAVHASSMNSSRRSFLLRGRGKHDEIEEDVRVSGDFLQNDSEGLIIRFNSVCLAPSFEYRR-LPGIQQGFSLEIPYRQKVGICGRSGSGKSTLLMGIVRLSRVL-QGSITINGININAIPLSRLRKFVITIPQDAVLFSGTIRSNLDPENDFSDELIWSTLDKADCGKTVRNFPDGLDTCVTENGDNFSLGQRQELNIVKALLRRPRVVILDESTSALDPNREVALHNTLLEAFEDSTLISVAHRLSNIVEYERVLVMGEGRILEDGNPKELLKKPMGFFSALWRA 1885 HSP 2 Score: 185.267 bits (469), Expect = 2.062e-47 Identity = 133/446 (29.82%), Postives = 227/446 (50.90%), Query Frame = 0
Query: 105 SLVGLLIILLFYPVMGIIATLTSKLRLRIVNVTDKRTTQMNEILNSIRLIKMYAWEKSFEDRVHKIRAHEIKELRKAAFLQSS---FTSITPSVTIIATIVTFFTLTASGYDLTAPEAFTVFSIFVSLQFTVGTLPYALKCLAEAKVSLVRLQKFMSLPEYMHPSSRNFNPDDPKNLRIQIQNANLGWTKAPEWETEDEKKKSK-------------VTNKKKKAEKG-SKDEAEVLKPKYEELSYTPCLFDINLTVEEGSLIGVAGPIGAGKSSLLSAIMGEMKQLTGDFK--IRGRMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKARGKTVLLVSHGMQFLEKCDSVIYVSNGKIIERGTHKEL 531
+++G +IL + G + + +KL I+ D R + E L S++ +K+ E+ R+ R E+ LR+ +FL S SI+ ++ T+ F L ++ TA + FT ++ L + +P + + KVS RL +F++ E + I QN L D++K + K+ E + + PK E T L INL ++ GSL V GP G+GK++L+S+++ EM ++TG K + +AL+ Q+ W+ N T+++NIL+G ++++RY+ VI AC L TD++LL +GD TEIGERGV LSGGQ+QR+ +AR LY+ +D P S++D+++ +F E +L L R +TV L + + FL + D ++ + +G I +GT +++
Sbjct: 525 AILGTCVILPLQVLTGKLMSENNKL---ILCSQDNRLFKSTETLASMKTVKLATMEEWALKRIRCARTKELIFLRRDSFLWSFMAFLASISTTLVTTLTLGLFVLL--EDHNFTAADLFTSMALLSQLTVCLSVVPVTVPIFIKGKVSTQRLAEFLNRAE----------------VSIYKQNNKLN----KHCTYFDDRKDDDEEEEEEEEESEIFIQRAKRLPETCFTVENGTFAWPKCE----TNVLQSINLEIKTGSLTIVIGPSGSGKTALISSLIEEMDRITGSVKWNVPDTVALLGQRPWLLNTTIKDNILLGRPFKEKRYKKVIAACDLQTDIDLLPHGDDTEIGERGVLLSGGQRQRLAIARCLYSKSYCTFMDAPFSSLDSKITSHVFEEGVLKILLKRRRTVFLTTERLDFLHRADHIVALKDGMIKAQGTIQDV 941 HSP 3 Score: 68.9366 bits (167), Expect = 8.396e-12 Identity = 56/204 (27.45%), Postives = 96/204 (47.06%), Query Frame = 0
Query: 350 IGVAGPIGAGKSSLLSAIMGEMKQLTGDFKIRG-------------RMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYIL--TQLKA-RGKTVLLVSHGMQFLEKCDSVIYVSNGKIIERGTHKELMEQTEG 537
+G+ G G+GKS+LL I+ + L G I G + + Q A +F+GT+R N+ + E + + +G T + E G N S GQ+Q +N+ +AL + +LD+ SA+D RE L T L+A T++ V+H + + + + V+ + G+I+E G KEL+++ G
Sbjct: 1680 VGICGRSGSGKSTLLMGIVRLSRVLQGSITINGININAIPLSRLRKFVITIPQDAVLFSGTIRSNLDPENDFSDELIWSTLDKADCGKTVRNFPDGLDTCVTENGDNFSLGQRQELNIVKALLRRPRVVILDESTSALDPN------REVALHNTLLEAFEDSTLISVAHRLSNIVEYERVLVMGEGRILEDGNPKELLKKPMG 1877
BLAST of multidrug resistance-associated protein 5 vs. L. salmonis genes
Match: EMLSAG00000003104 (supercontig:LSalAtl2s:LSalAtl2s174:364234:370462:-1 gene:EMLSAG00000003104 transcript:EMLSAT00000003104 description:"maker-LSalAtl2s174-augustus-gene-3.18") HSP 1 Score: 133.265 bits (334), Expect = 1.091e-31 Identity = 79/230 (34.35%), Postives = 127/230 (55.22%), Query Frame = 0
Query: 966 EHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFD-QYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLS 1194
E +ITF DV Y D + N +S + G+ + IVG +G+GK++LV L R E + GSI I +I E+ L LR I+++PQD VLF T+ N+ + +D ++ + + + I V G S GEKQ + + RA L+ + +++ DEAT+S+D T+ +I +K S T + +AHRL TVV+ D I V+ +G+++E G+ +ELL+
Sbjct: 360 EDASITFDDVKFGYNIDKNIA-NGLSFSVESGKTIAIVGESGSGKSTLVRLLYRFYEPQL-GSIKIGNYNINEVTLDSLRRQISIVPQDCVLFNDTIFHNIKYGNLNCSDEDVYKVAKLAEIDNAIRSWPQGYLTQVGERGLKLSGGEKQRVAIARAALKDSPIIIFDEATSSLDSITETMIMKALKRVTSGKTAIIIAHRLSTVVHADEIFVLSNGKVIERGTHEELLN 587 HSP 2 Score: 110.153 bits (274), Expect = 1.788e-24 Identity = 70/213 (32.86%), Postives = 118/213 (55.40%), Query Frame = 0
Query: 340 INLTVEEGSLIGVAGPIGAGKSSLLSAI-------MGEMKQLTGDFKI--------RGRMALVSQQAWIFNGTVRENILMGAV--YEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLK--ARGKTVLLVSHGMQFLEKCDSVIYVSNGKIIERGTHKELME 533
++ +VE G I + G G+GKS+L+ + +G +K G++ I R ++++V Q +FN T+ NI G + +++ Y+V + +D + G LT++GERG+ LSGG+KQRV +ARA D I + D+ S++D+ I I+ LK GKT ++++H + + D + +SNGK+IERGTH+EL+
Sbjct: 383 LSFSVESGKTIAIVGESGSGKSTLVRLLYRFYEPQLGSIK--IGNYNINEVTLDSLRRQISIVPQDCVLFNDTIFHNIKYGNLNCSDEDVYKVA-KLAEIDNAIRSWPQGYLTQVGERGLKLSGGEKQRVAIARAALKDSPIIIFDEATSSLDS-----ITETMIMKALKRVTSGKTAIIIAHRLSTVVHADEIFVLSNGKVIERGTHEELLN 587
BLAST of multidrug resistance-associated protein 5 vs. SwissProt
Match: gi|75072999|sp|Q8HXQ5.1|MRP1_BOVIN (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 731.48 bits (1887), Expect = 0.000e+0 Identity = 443/1223 (36.22%), Postives = 674/1223 (55.11%), Query Frame = 0
Query: 22 FGVNFVIGVHTAQRVLGALQYLAYSKLLRL--AAPNEAALGQLMTFFTGDQERITEGVIVGTLFLGTPILFIMSASYATYLVGPLSLVGLLIILLFYPVMGIIATLTSKLRLRIVNVTDKRTTQMNEILNSIRLIKMYAWEKSFEDRVHKIRAHEIKELRKAAFLQS--SFTSI-TPSVTIIATIVTFFTLTASGYDLTAPEAFTVFSIFVSLQFTVGTLPYALKCLAEAKVSLVRLQKFMSLPEYMHPSSRNFNP--DDPKNLRIQIQNANLGWTKAPEWETEDEKKKSKVTNKKKKAEKGSKDEAEVLKPKYEELSYTPCLFDINLTVEEGSLIGVAGPIGAGKSSLLSAIMGEMKQLTGDFKIRGRMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKARGKTVLLVSHGMQFLEKCDSVIYVSNGKIIERGTHKELMEQTEGQYLHMSTFDQSHKA--------SRTRGYSESLEQPTLDEKVDDRKGSLTKR---------------HASIVS----GSADETDQAKGAFTVEEGDVENAGWGVLYRYFQACGGLFIMFLLFLAILAFALARLFTSVWLQIWLDNG--DGLEQERMDNMTLYNMTYSDSEIKGFVTHNPDLWFYQTIYFVNLAIMVVIGLIKGIVLAFQFLKGSSKLHDAMLHRVMRSPMKFFDTTPSGRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMV---PFGVILVVFCVLDVIMNRGILETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQTCTFVPFVMRMKADFRARFNSVERVAEYATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMK 1205
F + FV G+ V+GA+ Y K L + AA + +G+++ + D +R + + P+ I++ +GP L G+ +++L P+ ++A T ++ + D R MNEILN I+++K+YAWE +F+D+V IR E+K L+K+A+L + +FT + TP + ++T + T+ + L A +AF ++F L+F + LP + + +A VSL RL+ F+S E + P S P D I ++NA W + + P L I +V EGSL+ V G +G GKSSLLSA++ EM ++ G ++G +A V QQAWI N ++RENIL G ++ Y+ V+ ACAL DLE+L +GD TEIGE+GVNLSGGQKQRV+LARA+Y D D+YLLDDPLSAVDA V K IF I + + KT LLV+H + +L + D +I +S GKI E G+++EL+ + + T+ + + + G + ++Q V D G +R H S G +ET + A + G V+ + V + Y +A GLFI FL L +A L ++ WL +W D+ +G ++ +++Y L Q I ++ V IG GI S +LH +LH V+RSP+ FF+ TPSG ++NRFSK++D +D +P + S+ + ++ P V P G+I V +R + K+LE+V++SPV H + + G+++IR ++ Q F ++ D ++ + A ANRW R++ VG ++ + F+V+ + S+S + GL+++ Q T++ +++RM ++ +VER+ EY ++ E+EAP I + P WP+ G + F+D LRYR+DL LVL I++ I GGEKVGIVGRTGAGK+SL L R+ E G I+ID ++IA+IGLHDLR I +IPQDPVLF G+LR N+DPF QY+D ++WT+LE +HLK +S ++L G+N SVG++QL+CL RALLRK K+L+LDEATA+VD++TD LIQ+TI+ F CTVLT+AHRL+T+++Y R+IV+ GEI E GSP +LL R G+F SM K
Sbjct: 385 FHICFVSGMRIKTAVIGAV----YRKALVITNAARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDENNI-LDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRVFLS-HEDLDPDSIQRRPIKDAGATNSITVKNATFTWAR----------------------------------------NDPPTLHGITFSVPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVTVKGSVAYVPQQAWIQNISLRENILFGRQLQERYYKAVVEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCDSDVYLLDDPLSAVDAHVGKHIFENVIGPKGLLKNKTRLLVTHAISYLPQMDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASAEQEQGQPEDGLAGVGGPGKEVKQMENGMLVTDTAGKQMQRQLSSSSSYSRDVSQHHTSTAELRKPGPTEETWKLVEADKAQTGQVKLS---VYWDYMKAI-GLFISFLSIFLFLCNHVASLVSNYWLSLWTDDPIVNGTQEHTQVRLSVYGA----------------LGISQGITVFGYSMAVSIG---GIF-------ASRRLHLDLLHNVLRSPISFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFNVIGACIIILLATPMAAVIIPPLGLIYFFVQRFYVASSR---QLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFASLFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEY-SETEKEAPWQIQDMAPPKDWPQVGRVEFRDYGLRYREDLDLVLKHINVTIDGGEKVGIVGRTGAGKSSLTLGLFRIKE-SAEGEIIIDDINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFDDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEWGSPSDLLQQR-GLFYSMAK 1525 HSP 2 Score: 84.7297 bits (208), Expect = 4.082e-15 Identity = 72/262 (27.48%), Postives = 123/262 (46.95%), Query Frame = 0
Query: 948 EQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATI---KEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMKS 1206
E P+ I +++P +IT K+ + + ++ P L+ I+ + G V +VG+ G GK+SL++ L L E +DKV G ++ ++A +PQ + +LR N+ Q + +E L + + + +G N S G+KQ + L RA+ + V LLD+ ++VD I + K T L V H + + D IIVM G+I E+GS +ELL+ R+G F +++
Sbjct: 623 EDLDPDSI-QRRPIKDAGATNSITVKNATFTWARNDPPTLHGITFSVPEGSLVAVVGQVGCGKSSLLSAL--LAE--------MDKVE----GHVTVKGSVAYVPQQAWIQNISLRENILFGRQLQERYYKAVVEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCDSDVYLLDDPLSAVDAHVGKHIFENVIGPKGLLKNKTRLLVTHAISYLPQMDVIIVMSGGKISEMGSYQELLA-RDGAFAEFLRT 868
BLAST of multidrug resistance-associated protein 5 vs. SwissProt
Match: gi|296439301|sp|P33527.3|MRP1_HUMAN (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 730.324 bits (1884), Expect = 0.000e+0 Identity = 441/1222 (36.09%), Postives = 673/1222 (55.07%), Query Frame = 0
Query: 22 FGVNFVIGVHTAQRVLGALQYLAYSKLLRL--AAPNEAALGQLMTFFTGDQERITEGVIVGTLFLGTPILFIMSASYATYLVGPLSLVGLLIILLFYPVMGIIATLTSKLRLRIVNVTDKRTTQMNEILNSIRLIKMYAWEKSFEDRVHKIRAHEIKELRKAAFLQS--SFTSI-TPSVTIIATIVTFFTLTASGYDLTAPEAFTVFSIFVSLQFTVGTLPYALKCLAEAKVSLVRLQKFMSLPEYMHPSSRNFNP--DDPKNLRIQIQNANLGWTKAPEWETEDEKKKSKVTNKKKKAEKGSKDEAEVLKPKYEELSYTPCLFDINLTVEEGSLIGVAGPIGAGKSSLLSAIMGEMKQLTGDFKIRGRMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKARGKTVLLVSHGMQFLEKCDSVIYVSNGKIIERGTHKELMEQTEGQYLHMSTF-----DQSHKASRTRGYS------ESLEQPTLDEKVDDRK------------GSLTKRHASIVSGSADETDQAKGAFTVEEGDVENAG---WGVLYRYFQACGGLFIMFLLFLAILAFALARLFTSVWLQIWLDNG--DGLEQERMDNMTLYNMTYSDSEIKGFVTHNPDLWFYQTIYFVNLAIMVVIGLIKGIVLAFQFLKGSSKLHDAMLHRVMRSPMKFFDTTPSGRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMV---PFGVILVVFCVLDVIMNRGILETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQTCTFVPFVMRMKADFRARFNSVERVAEYATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMK 1205
F + FV G+ V+GA+ Y K L + +A + +G+++ + D +R + + P+ I++ +GP L G+ +++L PV ++A T ++ + D R MNEILN I+++K+YAWE +F+D+V IR E+K L+K+A+L + +FT + TP + + T + T+ + L A AF ++F L+F + LP + + +A VSL RL+ F+S E + P S P D I ++NA W + S P L I ++ EG+L+ V G +G GKSSLLSA++ EM ++ G I+G +A V QQAWI N ++RENIL G E+ Y+ VI+ACAL DLE+L +GD TEIGE+GVNLSGGQKQRV+LARA+Y++ DIYL DDPLSAVDA V K IF I + + KT +LV+H M +L + D +I +S GKI E G+++EL+ + + T+ +Q + + G S + +E L ++ G +++ H S E + + + + E D G V + Y +A GLFI FL + ++ L ++ WL +W D+ +G ++ +++Y L Q I ++ V IG GI+ S LH +LH ++RSPM FF+ TPSG ++NRFSK++D +D +P + S+ + V+ P + P G+I V +R + K+LE+V++SPV H + + G+++IR ++ Q F + D ++ + A ANRW R++ VG ++ A F+V+ + S+S + GL+++ Q T++ +++RM ++ +VER+ EY ++ E+EAP I E P SSWP+ G + F++ LRYR+DL VL I++ I GGEKVGIVGRTGAGK+SL L R+ E G I+ID ++IA+IGLHDLR I +IPQDPVLF G+LR N+DPF QY+D ++WT+LE +HLK +S ++L G+N SVG++QL+CL RALLRK K+L+LDEATA+VD++TD LIQ+TI+ F CTVLT+AHRL+T+++Y R+IV+ GEI E G+P +LL R G+F SM K
Sbjct: 385 FHICFVSGMRIKTAVIGAV----YRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYVTIDENNI-LDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEE-LEPDSIERRPVKDGGGTNSITVRNATFTWAR----------------------------------------SDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASTEQEQDAEENGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSSSSYSGDISRHHNSTAELQKAEAKKEE-TWKLMEADKAQTGQVKLSVYWDYMKAI-GLFISFLSIFLFMCNHVSALASNYWLSLWTDDPIVNGTQEHTKVRLSVYGA----------------LGISQGIAVFGYSMAVSIG---GIL-------ASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSR---QLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEY-SETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINE-SAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQR-GLFYSMAK 1526 HSP 2 Score: 88.5817 bits (218), Expect = 2.298e-16 Identity = 75/279 (26.88%), Postives = 130/279 (46.59%), Query Frame = 0
Query: 948 EQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKV--HIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATI---KEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMKSVQMDHQASPVREAEE 1221
E+ P+ I E++P +IT ++ + + + P LN I+ I G V +VG+ G GK+SL++ L L E +DKV H+A ++ ++A +PQ + +LR N+ Q + + ++ L + + + +G N S G+KQ + L RA+ + L D+ ++VD I + K T + V H + + D IIVM G+I E+GS +ELL+ R+G F +++ Q ++AEE
Sbjct: 623 EELEPDSI-ERRPVKDGGGTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSAL--LAE--------MDKVEGHVA------IKGSVAYVPQQAWIQNDSLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLA-RDGAFAEFLRTYASTEQE---QDAEE 880
BLAST of multidrug resistance-associated protein 5 vs. SwissProt
Match: gi|85701143|sp|Q8CG09.2|MRP1_RAT (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 727.243 bits (1876), Expect = 0.000e+0 Identity = 438/1223 (35.81%), Postives = 674/1223 (55.11%), Query Frame = 0
Query: 22 FGVNFVIGVHTAQRVLGALQYLAYSKLLRL--AAPNEAALGQLMTFFTGDQERITEGVIVGTLFLGTPILFIMSASYATYLVGPLSLVGLLIILLFYPVMGIIATLTSKLRLRIVNVTDKRTTQMNEILNSIRLIKMYAWEKSFEDRVHKIRAHEIKELRKAAFLQS--SFTSI-TPSVTIIATIVTFFTLTASGYDLTAPEAFTVFSIFVSLQFTVGTLPYALKCLAEAKVSLVRLQKFMSLPEYMHPSSRNFNPDDPKNLR-IQIQNANLGWTKAPEWETEDEKKKSKVTNKKKKAEKGSKDEAEVLKPKYEELSYTPCLFDINLTVEEGSLIGVAGPIGAGKSSLLSAIMGEMKQLTGDFKIRGRMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKARGKTVLLVSHGMQFLEKCDSVIYVSNGKIIERGTHKELMEQTEGQYLHMSTF-----------DQSHKASRTRGYSESLEQPTLDEKVDDRKGSLTKRHASIVSGSADETDQAKGAFT-VEEGDVENAGW---------------GVLYRYFQACGGLFIMFLLFLAILAFALARLFTSVWLQIWLDNG---DGLEQERMDNMTLYNMTYSDSEIKGFVTHNPDLWFYQTIYFVNLAIMVVIGLIKGIVLAFQFLKGSSKLHDAMLHRVMRSPMKFFDTTPSGRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMV---PFGVILVVFCVLDVIMNRGILETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQTCTFVPFVMRMKADFRARFNSVERVAEYATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMK 1205
F + FV G+ V+GA+ Y K L + +A + +G+++ + D +R + + P+ ++ + +GP L G+ +++L P ++A T ++ + D R MNEILN I+++K+YAWE +F+D+V IR E+K L+K+A+L + +FT + TP + ++T F T+ L A +AF ++F L+F + LP + + +A VSL RL+ F+S E S ++ D + I ++NA W ++DE P L I + +G+L+ V G +G GKSSLLSA++ EM ++ G ++G +A V QQAWI N ++RENIL G ++ Y+ V+ ACAL DLE+L +GDLTEIGE+GVNLSGGQKQRV+LARA+Y + DIYLLDDPLSAVDA V K IF + + + KT +LV+HG+ +L + D +I +S GKI E G+++EL+++ + T+ D + S S+ +E L V D G +RH S S + T+Q + +++ V+ W V + Y +A GL I FL L ++ L ++ WL +W D+ +G ++ R +++Y L Q + ++ V IG GI S +LH +L V+RSPM FF+ TPSG ++NRFSK++D +D +P + S+ + + ++ P V P G++ V +R + K+LE+V++SPV H + + G+++IR ++ Q F ++ D ++ + A ANRW R++ VG ++ A F+V+ + S+S + GL+++ Q ++ +++RM ++ +VER+ EY ++ E+EA I E P S+WP G + F+D LRYR+DL LVL I++ I GGEKVGIVGRTGAGK+SL L R+ E G I+ID ++IA+IGLH+LR I +IPQDPVLF G+LR N+DPF QY+D ++W ALE +HLK +S ++L G+N SVG++QL+CL RALLRK K+L+LDEATA+VD++TD LIQ+TI+ F TVLT+AHRL+T+++Y R+IV+ GEI E G+P ELL R GVF SM K
Sbjct: 386 FHICFVTGMRIKTAVVGAV----YRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVTLALYFLWLNLGPSVLAGVAVMILMVPFNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFQDKVMNIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVFVTVDEKNI-LDAKKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERWSIKDGGGMNSITVKNATFTW---------------------------ARDEP-------------PTLNGITFAIPDGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVTLKGSVAYVPQQAWIQNDSLRENILFGRPLQEHCYKAVMEACALLPDLEILPSGDLTEIGEKGVNLSGGQKQRVSLARAVYCNSDIYLLDDPLSAVDAHVGKHIFEKVVGPMGLLKNKTRILVTHGISYLPQVDVIIVMSGGKISEMGSYQELLDRDGAFAEFVRTYANTEQDLASEDDSKNGVSGLGKESKPVENGIL---VTDAVGKPLQRHLSNSSSHSVVTNQQHSSTAELQKSGVKEETWKLMEADKAQTGQVKLSVYWNYMKAI-GLCISFLSIFLFLCNHVSALASNYWLSLWTDDRPAVNGTQENRNFRLSVYGA----------------LGILQGVAVFGYSMAVSIG---GIF-------ASRRLHLDLLQNVLRSPMSFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFSVIGAVIIILLATPIAAVIIPPLGLVYFFVQRFYVASSR---QLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQITAYLNWLVRMSSEMETNIVAVERLKEY-SETEKEASWQIQETAPPSTWPHSGRVEFRDYCLRYREDLDLVLKHINVTIEGGEKVGIVGRTGAGKSSLTLGLFRINE-SAEGEIIIDGINIAKIGLHNLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWMALELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDSTVLTIAHRLNTIMDYTRVIVLDKGEIRECGAPSELLQQR-GVFYSMAK 1527
BLAST of multidrug resistance-associated protein 5 vs. SwissProt
Match: gi|3219824|sp|Q63120.1|MRP2_RAT (RecName: Full=Canalicular multispecific organic anion transporter 1; AltName: Full=ATP-binding cassette sub-family C member 2; AltName: Full=Canalicular multidrug resistance protein; AltName: Full=Multidrug resistance-associated protein 2) HSP 1 Score: 725.702 bits (1872), Expect = 0.000e+0 Identity = 433/1266 (34.20%), Postives = 693/1266 (54.74%), Query Frame = 0
Query: 10 VLLVSQFFRAVTFGVNFVIGVHTAQRVLGALQYLAYSKLLRLA--APNEAALGQLMTFFTGDQERITEGVIVGTLFLGTPILFIMSASYATYLVGPLSLVGLLIILLFYPVMGIIATLTSKLRLRIVNVTDKRTTQMNEILNSIRLIKMYAWEKSFEDRVHKIRAHEIKELRKAAFLQSSFTSITPSVTIIATIVTF--FTLTASGYDLTAPEAFTVFSIFVSLQFTVGTLPYALKCLAEAKVSLVRLQKFMSLPEYMHPSSRNFNPDDPKNLRIQIQNANLGWTKAPEWETEDEKKKSKVTNKKKKAEKGSKDEAEVLKPKYEELSYT------PCLFDINLTVEEGSLIGVAGPIGAGKSSLLSAIMGEMKQLTGDFKIRGRMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKARGKTVLLVSHGMQFLEKCDSVIYVSNGKIIERGTHKELMEQTEGQYLHMSTFDQSHKA----SRTRGYSESLEQ-----PTLDEKVDDR-----------------------------KGSLTKRHASIVSGSADETDQAK--GAFTVEEGDVENAGWGVLYRYFQACGGLFIMFLLFLAILAFALARLFTSVWLQIWLDNGDGLEQERMDNMTLYNMTYSDSEIKGFVTHNPDLWFYQTIYFVNLAIMVVIGLIKGIVLAFQFL-------KGSSKLHDAMLHRVMRSPMKFFDTTPSGRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQIS----VVCFVYPYF---MVPFGVILVVFCVLDVIMNRGILETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQTCTFVPFVMRMKADFRARFNSVERVAEYATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMKSVQMDH 1211
V L+ F F FV+G+ V+ ++ Y K L L+ A + +G+ + + D +++ + L + I +S + +GP L G+ +++L PV G++AT ++++ + DKR MNEIL+ I+++K +AWE SF+++V IR E+K L + LQS I I+ ++VTF + L S L A +AFT ++F L+F + LP + +A VS+ RL++++ DD D +V+N K K+ E S+T + D+NL ++ G L+ V G +G+GKSSL+SA++GEM+ + G I+G A V QQ+WI NGT+++NIL G+ Y +++YQ V++ACAL DLE+L GD+ EIGE+G+NLSGGQKQRV+LARA Y D DIY+LDDPLSAVDA V K IF + + GKT + V+HG+ FL + D ++ + G I+E+G++++L+++ + TF H + SE+ + PT++E +D K SL ++ +++ E + K VE G V+ + + +Y QA G I+F++ L +A + +++WL W + D L N T + ++ D I + +GL +GI L L S LH +L ++R+PM+FFDTTP+GRI+NRFS D+ +D +P +S + C I+ ++C P F ++P ++ + V V +R + ++L++VTKSP+ H S + G+ IIR ++ Q F ++ ++I+ + +NRW R+++VG L + +A V+++ +++ + G L+N + +++RM ++ +VER++EY ++E EAP ++ +K+P + WP HG I F + +RYR +L LVL I+ +I GEKVG+VGRTGAGK+SL L R+ E G I+ID + +A IGLHDLR + +IPQDP+LF G+LR N+DPF++Y+D ++W ALE +HL++ +SG Q L V GDN S+G++QL+CL RA+LRK+K+L+LDEATA+VD++TD LIQ TI++ FS+CTV+T+AHRLHT+++ D+I+V+ +G+IVE GSP+ELLSNR G F M K +++
Sbjct: 366 VTLIQSFCLQSYFQHCFVLGMCVRTTVMSSI----YKKALTLSNLARKQYTIGETVNLMSVDSQKLMDATNYMQLVWSSVIQITLSIFFLWRELGPSILAGVGVMVLLIPVNGVLATKIRNIQVQNMKNKDKRLKIMNEILSGIKILKYFAWEPSFQEQVQGIRKKELKNLLRFGQLQSLLIFILQITPILVSVVTFSVYVLVDSANVLNAEKAFTSITLFNILRFPLSMLPMVTSSILQASVSVDRLERYLG-------------GDDL-----------------------DTSAIRRVSNFDKAV-------------KFSEASFTWDPDLEATIQDVNLDIKPGQLVAVVGTVGSGKSSLVSAMLGEMENVHGHITIQGSTAYVPQQSWIQNGTIKDNILFGSEYNEKKYQQVLKACALLPDLEILPGGDMAEIGEKGINLSGGQKQRVSLARAAYQDADIYILDDPLSAVDAHVGKHIFNKVVGPNGLLAGKTRIFVTHGIHFLPQVDEIVVLGKGTILEKGSYRDLLDKKGVFARNWKTF-MKHSGPEGEATVNNDSEAEDDDDGLIPTMEEIPEDAASLAMRRENSLRRTLSRSSRSSSRRGKSLKNSLKIKNVNVLKEKEKEVEGQKLIKKEFVETGKVK---FSIYLKYLQAVGWWSILFIILFYGLN-NVAFIGSNLWLSAWTSDSDNL------NGTNNSSSHRDMRI---------------------GVFGALGLAQGICLLISTLWSIYACRNASKALHGQLLTNILRAPMRFFDTTPTGRIVNRFSGDISTVDDLLP----QTLRSWMMCFFGIAGTLVMICMATPVFAIIIIPLSILYISVQVFYVATSR---QLRRLDSVTKSPIYSHFSETVTGLPIIRAFEHQQRFLAWNEKQIDINQKCVFSWITSNRWLAIRLELVGNLVVFCSALLLVIYRKTLTGDVVGFVLSNALNITQTLNWLVRMTSEAETNIVAVERISEY-INVENEAP-WVTDKRPPADWPRHGEIQFNNYQVRYRPELDLVLKGITCNIKSGEKVGVVGRTGAGKSSLTNCLFRILE-SAGGQIIIDGIDVASIGLHDLRERLTIIPQDPILFSGSLRMNLDPFNKYSDEEVWRALELAHLRSFVSGLQLGLLSEVTEGGDNLSIGQRQLLCLGRAVLRKSKILVLDEATAAVDLETDSLIQTTIRKEFSQCTVITIAHRLHTIMDSDKIMVLDNGKIVEYGSPEELLSNR-GSFYLMAKEAGIEN 1535 HSP 2 Score: 90.1225 bits (222), Expect = 9.233e-17 Identity = 112/477 (23.48%), Postives = 204/477 (42.77%), Query Frame = 0
Query: 772 QSVLFCVTQISVVCFVY-----PYFMVPFGVILVVFCVLDVIMNRGILETK----KLENV-TKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGS----VSPAIAGLALANVFQ-TCTFVPFVMR--MKADFRARFNSVERVAEY--ATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKC----------TVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMKSVQMDHQASPVREA 1219
Q V V QI++ F P + GV++++ V G+L TK +++N+ K + ++ ++GI I++ + + FQ++ L + +F + I +L V+T + V+ + A + L N+ + + +P V ++A SV+R+ Y DL+ A + A + F + S + DL + +++DI G+ V +VG G+GK+SLV+ + L E+E VH G ++ + A +PQ + GT++ N+ +Y + + L+ L + + +G N S G+KQ + L RA + + +LD+ ++VD K F+K T + V H +H + D I+V+ G I+E GS ++LL ++ GVF K+ M H + P EA
Sbjct: 435 QLVWSSVIQITLSIFFLWRELGPSILAGVGVMVLLIPV------NGVLATKIRNIQVQNMKNKDKRLKIMNEILSGIKILKYFAWEPSFQEQVQGIRKKELKNLLRFGQLQSLLIFILQITPILVSVVTFSVYVLVDSANVLNAEKAFTSITLFNILRFPLSMLPMVTSSILQASV-----SVDRLERYLGGDDLDTSAIRRVSNFDKA--------VKFSEASFTWDPDLEATIQDVNLDIKPGQLVAVVGTVGSGKSSLVSAM--LGEME--------NVH----GHITIQGSTAYVPQQSWIQNGTIKDNILFGSEYNEKKYQQVLKACALLPDLEILPGGDMAEIGEKGINLSGGQKQRVSLARAAYQDADIYILDDPLSAVDAHVG-------KHIFNKVVGPNGLLAGKTRIFVTHGIHFLPQVDEIVVLGKGTILEKGSYRDLL-DKKGVFARNWKTF-MKH-SGPEGEA 868
BLAST of multidrug resistance-associated protein 5 vs. SwissProt
Match: gi|75072869|sp|Q864R9.1|MRP1_MACFA (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 724.931 bits (1870), Expect = 0.000e+0 Identity = 438/1222 (35.84%), Postives = 673/1222 (55.07%), Query Frame = 0
Query: 22 FGVNFVIGVHTAQRVLGALQYLAYSKLLRL--AAPNEAALGQLMTFFTGDQERITEGVIVGTLFLGTPILFIMSASYATYLVGPLSLVGLLIILLFYPVMGIIATLTSKLRLRIVNVTDKRTTQMNEILNSIRLIKMYAWEKSFEDRVHKIRAHEIKELRKAAFLQS--SFTSI-TPSVTIIATIVTFFTLTASGYDLTAPEAFTVFSIFVSLQFTVGTLPYALKCLAEAKVSLVRLQKFMSLPEYMHPSSRNFNP--DDPKNLRIQIQNANLGWTKAPEWETEDEKKKSKVTNKKKKAEKGSKDEAEVLKPKYEELSYTPCLFDINLTVEEGSLIGVAGPIGAGKSSLLSAIMGEMKQLTGDFKIRGRMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKARGKTVLLVSHGMQFLEKCDSVIYVSNGKIIERGTHKELMEQTEGQYLHMSTF-----DQSHKASRTRGYS------ESLEQPTLDEKVDDRK------------GSLTKRHASIVSGSADETDQAKGAFTVEEGDVENAG---WGVLYRYFQACGGLFIMFLLFLAILAFALARLFTSVWLQIWLDNG--DGLEQERMDNMTLYNMTYSDSEIKGFVTHNPDLWFYQTIYFVNLAIMVVIGLIKGIVLAFQFLKGSSKLHDAMLHRVMRSPMKFFDTTPSGRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMV---PFGVILVVFCVLDVIMNRGILETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQTCTFVPFVMRMKADFRARFNSVERVAEYATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMK 1205
F + FV G+ V+GA+ Y K L + AA + +G+++ + D +R + + P+ I++ +GP L G+ +++L PV ++A T ++ + D R MNEILN I+++K+YAWE +F+D+V IR E+K L+K+A+L + +FT + TP + + T + T+ + L A +AF ++F L+F + LP + + +A VSL RL+ F+S E + P S P D I ++NA W + S P L I ++ EG+L+ V G +G GKSSLLSA++ EM ++ G ++G +A V QQAWI N +++ENIL G E+ Y+ VI+ACAL DLE+L +GD TEIGE+GVNLSGGQKQRV+LARA+Y + DIYL DDPLSAVDA V K IF I + + KT +LV+H M +L + D +I +S GKI E G+++EL+ + + T+ +Q + + G S + +E L ++ G ++++H S D + + + + E D G V + Y +A G LFI FL + +A L ++ WL +W D+ +G ++ +++Y L Q I ++ V IG GI+ S LH +LH ++RSPM FF+ TPSG ++NRFSK++D +D +P + S+ + V+ P + P G+I V +R + K+LE+V++SPV H + + G+++IR ++ Q F + D ++ + A ANRW R++ VG ++ A F+V+ + S+S + GL+++ Q T++ +++RM ++ +VER+ EY ++ E+EAP I E P S+WP+ G + F++ LRYR+DL VL I++ I GGEKVGIVGRTGAGK+SL L R+ E G I+ID ++IA IGLHDLR I +IPQDPVLF G+LR N+DPF QY+D ++WT+LE +HLK +S ++L G+N SVG++QL+CL RALLRK K+L+LDEATA+VD++TD LIQ+TI+ F CTVLT+AHRL+T+++Y R+IV+ GEI E G+P +LL R G+F +M +
Sbjct: 385 FHICFVSGMRIKTAVIGAV----YRKALVITNAARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWRNLGPPILAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALCTFAVYVTIDKNNV-LDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEE-LEPDSIERRPVKDGGDTNSITVRNATFTWAR----------------------------------------SDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVALKGSVAYVPQQAWIQNDSLQENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASAEQEQDPEDNGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSSSSYSGDVSRQHNSTAELQKDGAKKEE-TWKLMEADKAQTGQVKLSVYWDYMKAIG-LFISFLSIFLFICNHVAALASNYWLSLWTDDPIVNGTQEHTKVRLSVYGA----------------LGISQGIAVFGYSMAVSIG---GIL-------ASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSR---QLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEY-SETEKEAPWQIQETAPPSNWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINE-SAEGEIIIDGINIARIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKGFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQR-GLFYNMAR 1526 HSP 2 Score: 87.4261 bits (215), Expect = 6.134e-16 Identity = 72/270 (26.67%), Postives = 126/270 (46.67%), Query Frame = 0
Query: 948 EQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKV--HIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATI---KEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMKSVQMDHQ 1212
E+ P+ I E++P + +IT ++ + + + P LN I+ I G V +VG+ G GK+SL++ L L E +DKV H+A L+ ++A +PQ + +L+ N+ Q + + ++ L + + + +G N S G+KQ + L RA+ + L D+ ++VD I + K T + V H + + D IIVM G+I E+GS +ELL+ R+G F +++ Q
Sbjct: 623 EELEPDSI-ERRPVKDGGDTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSAL--LAE--------MDKVEGHVA------LKGSVAYVPQQAWIQNDSLQENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLA-RDGAFAEFLRTYASAEQ 874
BLAST of multidrug resistance-associated protein 5 vs. SwissProt
Match: gi|206729914|sp|O15439.3|MRP4_HUMAN (RecName: Full=Multidrug resistance-associated protein 4; AltName: Full=ATP-binding cassette sub-family C member 4; AltName: Full=MRP/cMOAT-related ABC transporter; AltName: Full=Multi-specific organic anion transporter B; Short=MOAT-B) HSP 1 Score: 720.694 bits (1859), Expect = 0.000e+0 Identity = 437/1220 (35.82%), Postives = 664/1220 (54.43%), Query Frame = 0
Query: 6 TLVLVLLVSQFFRAVTFGVNFVIGVHTAQRVLGALQYLAYSKLLRLA--APNEAALGQLMTFFTGDQERITEGVIVGTLFLGTPILFIMSASYATYLVGPLSLVGLLIILLFYPVMGIIATLTSKLRLRIVNVTDKRTTQMNEILNSIRLIKMYAWEKSFEDRVHKIRAHEIKELRKAAFLQSSFTSITPSVTIIATIVTFFTLTASGYDLTAPEAFTVFSIFVSLQFTVGTL-PYALKCLAEAKVSLVRLQKFMSLPEYMHPSSRNFN-PDDPKNLRIQIQNANLGWTKAPEWETEDEKKKSKVTNKKKKAEKGSKDEAEVLKPKYEELSYTPCLFDINLTVEEGSLIGVAGPIGAGKSSLLSAIMGEMKQLTGDFKIRGRMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKARGKTVLLVSHGMQFLEKCDSVIYVSNGKIIERGTHKELMEQ--TEGQYLHMSTFDQSHKAS------RTRGYSESLEQPTLDEKVDDRKGSLTKRHASIVSGSADETDQAKGAFTVEEGDVENAGWGVLYRYFQACGGLFIMFLLFLAILAFALARLFTSVWLQIWLDNGDGLEQERMDNMTLYNMTYSDSEIKGFVTHNPDLWFYQTIYFVNLAIMVVIGLIKGIVLAFQFLKGSSKLHDAMLHRVMRSPMKFFDTTPSGRILNRFSKDMDELDVRMPF-FTEFVCQSVLFCVTQISVVCFVYPYFMVPFGVILVVFCVLDVIMNRGILET----KKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQTCTFVPFVMRMKADFRARFNSVERVAEYATDLEQEAP-EYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMKSV 1207
TL+L +L +F V R+ A+ ++ Y K LRL+ A + GQ++ + D + + + P+ I + +G L G+ ++++ P+ L S LR + TD R MNE++ IR+IKMYAWEKSF + + +R EI ++ +++ L+ + S + I VTF T G +TA F +++ +++ TV P A++ ++EA VS+ R+Q F+ L E S RN P D K + + +Q+ W KA E TP L ++ TV G L+ V GP+GAGKSSLLSA++GE+ G + GR+A VSQQ W+F+GT+R NIL G YEKERY+ VI+ACAL DL+LL +GDLT IG+RG LSGGQK RVNLARA+Y D DIYLLDDPLSAVDA V++ +F E + Q+ K +LV+H +Q+L+ ++ + +GK++++GT+ E ++ G L + R R +SES + + G+L + V + E ++++G G+ YF+A + L L A +A + WL W + ++ M N+T+ G VT DL +Y IY V+ G+ + +++ + + S LH+ M ++++P+ FFD P GRILNRFSKD+ LD +P F +F+ Q++L V +SV V P+ +P LV ++ + + R LET K+LE+ T+SPV HLSS++ G+ IR Y+ + Q+ FD ++H A L+ +RWF R+D + + +++ A S++ ++ GLAL+ + +R A+ SVERV EY TDLE+EAP EY +K+P +WP G I F +V+ Y PLVL ++ I EKVGIVGRTGAGK+SL++ L RL+E P G I IDK+ EIGLHDLR +++IPQ+PVLF GT+R N+DPF+++TD ++W AL++ LK I ++ + G NFSVG++QL+CL RA+LRKN++L++DEATA+VD +TD LIQ I+E F+ CTVLT+AHRL+T+++ D+I+V+ SG + E P LL N+ +F M++ +
Sbjct: 145 TLILAILHHLYFYHVQCA---------GMRLRVAMCHMIYRKALRLSNMAMGKTTTGQIVNLLSNDVNKFDQVTVFLHFLWAGPLQAIAVTALLWMEIGISCLAGMAVLIILLPLQSCFGKLFSSLRSKTATFTDARIRTMNEVITGIRIIKMYAWEKSFSNLITNLRKKEISKILRSSCLRGMNLASFFSASKIIVFVTFTTYVLLGSVITASRVFVAVTLYGAVRLTVTLFFPSAIERVSEAIVSIRRIQTFLLLDEI---SQRNRQLPSDGKKM-VHVQDFTAFWDKASE---------------------------------------TPTLQGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHGLVSVHGRIAYVSQQPWVFSGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLF-ELCICQI-LHEKITILVTHQLQYLKAASQILILKDGKMVQKGTYTEFLKSGIDFGSLLKKDNEESEQPPVPGTPTLRNRTFSESSVWSQQSSRPSLKDGALESQDTENVPVTLSEENRSEG----------KVGFQAYKNYFRAGAHWIVFIFLILLNTAAQVAYVLQDWWLSYWAN------KQSMLNVTVNG--------GGNVTEKLDLNWYLGIYSGLTVATVLFGIARSLLVFYVLVNSSQTLHNKMFESILKAPVLFFDRNPIGRILNRFSKDIGHLDDLLPLTFLDFI-QTLLQVVGVVSVAVAVIPWIAIP----LVPLGIIFIFLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAMFVIIVAFGSLILAKTLDAGQVGLALSYALTLMGMFQWCVRQSAEVENMMISVERVIEY-TDLEKEAPWEY--QKRPPPAWPHEGVIIFDNVNFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSE--PEGKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNEHTDEELWNALQEVQLKETIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPYVLLQNKESLFYKMVQQL 1276
BLAST of multidrug resistance-associated protein 5 vs. SwissProt
Match: gi|308153583|sp|Q92887.3|MRP2_HUMAN (RecName: Full=Canalicular multispecific organic anion transporter 1; AltName: Full=ATP-binding cassette sub-family C member 2; AltName: Full=Canalicular multidrug resistance protein; AltName: Full=Multidrug resistance-associated protein 2) HSP 1 Score: 716.842 bits (1849), Expect = 0.000e+0 Identity = 415/1236 (33.58%), Postives = 677/1236 (54.77%), Query Frame = 0
Query: 12 LVSQFFRAVTFGVNFVIGVHTAQRVLGALQYLAYSKLLRLA--APNEAALGQLMTFFTGDQERITEGVIVGTLFLGTPILFIMSASYATYLVGPLSLVGLLIILLFYPVMGIIATLTSKLRLRIVNVTDKRTTQMNEILNSIRLIKMYAWEKSFEDRVHKIRAHEIKELRKAAFLQSSFTSITPSVTIIATIVTF--FTLTASGYDLTAPEAFTVFSIFVSLQFTVGTLPYALKCLAEAKVSLVRLQKFMSLPEYMHPSSRNFNPDDPKNLRIQIQNANLGWTKAPEWETEDEKKKSKVTNKKKKAEKGSKDEAEVLKPKYEELSYTPCLFDINLTVEEGSLIGVAGPIGAGKSSLLSAIMGEMKQLTGDFKIRGRMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKARGKTVLLVSHGMQFLEKCDSVIYVSNGKIIERGTHKELMEQTEGQYL-HMSTF-------------DQSHKASRTRGYSESLEQPTLD------------------------EKVDDRKGSLTKRHASIVSGSADETDQAKGAFTVEEGDVENA--GWGVLYRYFQACGGLFIMFLLFLAILAFALARLFTSVWLQIWLDNGDGLEQERMDNMTLYNMTYSDSEIKGFVTHNPDLWFYQTIYFVNLAIMVVIGLIKGIVL-------AFQFLKGSSKLHDAMLHRVMRSPMKFFDTTPSGRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYF---MVPFGVILVVFCVLDVIMNRGILETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQTCTFVPFVMRMKADFRARFNSVERVAEYATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELL 1193
L+ F F + F +GV ++ ++ Y K L L+ A E +G+ + + D +++ + + + + ++S + +GP L G+ +++L P+ I++T + ++++ + DKR MNEIL+ I+++K +AWE SF D+V +R E+K L + LQ + ++ ++VTF + L S L A +AFT ++F L+F + LP + + +A VS RL+K++ + + R+ D + +Q A+ W E + D+NL + G L+ V GP+G+GKSSL+SA++GEM+ + G I+G A V QQ+WI NGT+++NIL G + ++RYQ V+ ACAL DLE+L GDL EIGE+G+NLSGGQKQR++LARA Y ++DIYLLDDPLSAVDA V K IF + + +GKT LLV+H M FL + D ++ + NG I+E+G++ L+ + +G++ ++ TF D S + G S+E+ D + + SL R+ V+ ++ + KG +++ +E + + Y QA GLF +F + LA + ++A + +++WL W + ++ N T Y + D + + +GL +GI + AF F+ S+ LH +L+ ++R+PM+FFDTTP+GRI+NRF+ D+ +D +P L ++ + ++C P F ++P G+I V + V +R + ++L++VT+SP+ H S ++G+ +IR ++ Q F K + ++ + + +NRW R+++VG LT+ +A V+++ ++S G L+N + +++RM ++ +VER+ EY T +E EAP ++ +K+P WP G I F + +RYR +L LVL I+ DI EK+G+VGRTGAGK+SL L R+ E G I+ID V IA IGLHDLR + +IPQDP+LF G+LR N+DPF+ Y+D +IW ALE +HLK+ ++ Q L+ V G N S+G++QL+CL RALLRK+K+L+LDEATA+VD++TD LIQ TI+ F+ CTV+T+AHRLHT+++ D+++V+ +G+I+E GSP+ELL
Sbjct: 372 LIQSFCLQCYFQLCFKLGVKVRTAIMASV----YKKALTLSNLARKEYTVGETVNLMSVDAQKLMDVTNFMHMLWSSVLQIVLSIFFLWRELGPSVLAGVGVMVLVIPINAILSTKSKTIQVKNMKNKDKRLKIMNEILSGIKILKYFAWEPSFRDQVQNLRKKELKNLLAFSQLQCVVIFVFQLTPVLVSVVTFSVYVLVDSNNILDAQKAFTSITLFNILRFPLSMLPMMISSMLQASVSTERLEKYLGGDDLDTSAIRH---DCNFDKAMQFSEASFTWEHDSE----------------------------------------ATVRDVNLDIMAGQLVAVIGPVGSGKSSLISAMLGEMENVHGHITIKGTTAYVPQQSWIQNGTIKDNILFGTEFNEKRYQQVLEACALLPDLEMLPGGDLAEIGEKGINLSGGQKQRISLARATYQNLDIYLLDDPLSAVDAHVGKHIFNKVLGPNGLLKGKTRLLVTHSMHFLPQVDEIVVLGNGTIVEKGSYSALLAK-KGEFAKNLKTFLRHTGPEEEATVHDGSEEEDDDYGLISSVEEIPEDAASITMRRENSFRRTLSRSSRSNGRHLKSLRNSLKTRN---VNSLKEDEELVKGQKLIKKEFIETGKVKFSIYLEYLQAI-GLFSIFFIILAFVMNSVAFIGSNLWLSAWTSDS------KIFNSTDYPASQRDMRV---------------------GVYGALGLAQGIFVFIAHFWSAFGFVHASNILHKQLLNNILRAPMRFFDTTPTGRIVNRFAGDISTVDDTLPQSLRSWITCFLGIISTLVMICMATPVFTIIVIPLGIIYVSVQMFYVSTSR---QLRRLDSVTRSPIYSHFSETVSGLPVIRAFEHQQRFLKHNEVRIDTNQKCVFSWITSNRWLAIRLELVGNLTVFFSALMMVIYRDTLSGDTVGFVLSNALNITQTLNWLVRMTSEIETNIVAVERITEY-TKVENEAP-WVTDKRPPPDWPSKGKIQFNNYQVRYRPELDLVLRGITCDIGSMEKIGVVGRTGAGKSSLTNCLFRILE-AAGGQIIIDGVDIASIGLHDLREKLTIIPQDPILFSGSLRMNLDPFNNYSDEEIWKALELAHLKSFVASLQLGLSHEVTEAGGNLSIGQRQLLCLGRALLRKSKILVLDEATAAVDLETDNLIQTTIQNEFAHCTVITIAHRLHTIMDSDKVMVLDNGKIIECGSPEELL 1522 HSP 2 Score: 83.9593 bits (206), Expect = 6.304e-15 Identity = 112/484 (23.14%), Postives = 208/484 (42.98%), Query Frame = 0
Query: 746 GRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVY----PYFMVPFGVILVVFCVLDVIMNRG-ILETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFD----RDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQTCTFVPFVM--RMKADFRARFNSVERVAEY--ATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKC----------TVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMKS 1206
G +N S D +L + + F + SVL V I F++ P + GV+++V + ++ + ++ K ++N K I ++ ++GI I++ + + F+ + ++L L+ + L FVF++ V ++++V + + +V ++ A +F F P M M + S ER+ +Y DL+ A + A + F + S + D + +++DI G+ V ++G G+GK+SL++ + L E+E VH G ++ A +PQ + GT++ N+ ++ + + LE L + + +G N S G+KQ I L RA + + LLD+ ++VD K F+K T L V H +H + D I+V+ +G IVE GS LL+ + G F +K+
Sbjct: 418 GETVNLMSVDAQKL-MDVTNFMHMLWSSVLQIVLSI---FFLWRELGPSVLAGVGVMVLVIPINAILSTKSKTIQVKNMKNKDKRLKI--MNEILSGIKILKYFAWEPSFRDQVQNLRKKELKNLLAFSQLQCVVI--FVFQLTPV-LVSVVTFSVYVLVDSNNILDAQKAFTSITLFNILRF-PLSMLPMMISSMLQASVSTERLEKYLGGDDLDTSAIRHDCNFDKA--------MQFSEASFTWEHDSEATVRDVNLDIMAGQLVAVIGPVGSGKSSLISAM--LGEME--------NVH----GHITIKGTTAYVPQQSWIQNGTIKDNILFGTEFNEKRYQQVLEACALLPDLEMLPGGDLAEIGEKGINLSGGQKQRISLARATYQNLDIYLLDDPLSAVDAHVG-------KHIFNKVLGPNGLLKGKTRLLVTHSMHFLPQVDEIVVLGNGTIVEKGSYSALLA-KKGEFAKNLKT 861 HSP 3 Score: 80.4925 bits (197), Expect = 7.454e-14 Identity = 76/265 (28.68%), Postives = 124/265 (46.79%), Query Frame = 0
Query: 297 TEDEKKKSKVTNKKKKAEKGSKDEAEVLKPKYEELSYTPCLFDI---NLTVEEGSL--IGVAGPIGAGKSSLLSAIMGEMKQLTGDFKIRG-------------RMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKARGKTVLLVSHGMQFLEKCDSVIYVSNGKIIERGTHKELMEQTEGQYLHMS 543
T+ E + VT+K+ + SK + + ++ Y P L D+ +T + GS+ IGV G GAGKSSL + + ++ G I G ++ ++ Q +F+G++R N+ Y E + L + + L G E+ E G NLS GQ+Q + L RAL I +LD+ +AVD I Q + TV+ ++H + + D V+ + NGKIIE G+ +EL+ Q G + M+
Sbjct: 1276 TKVENEAPWVTDKRPPPDWPSKGKIQF---NNYQVRYRPEL-DLVLRGITCDIGSMEKIGVVGRTGAGKSSLTNCLFRILEAAGGQIIIDGVDIASIGLHDLREKLTIIPQDPILFSGSLRMNLDPFNNYSDEEIWKALELAHLKSFVASLQLGLSHEVTEAGGNLSIGQRQLLCLGRALLRKSKILVLDEATAAVDLETDNLI---QTTIQNEFAHCTVITIAHRLHTIMDSDKVMVLDNGKIIECGSPEELL-QIPGPFYFMA 1532
BLAST of multidrug resistance-associated protein 5 vs. SwissProt
Match: gi|338817955|sp|Q8VI47.2|MRP2_MOUSE (RecName: Full=Canalicular multispecific organic anion transporter 1; AltName: Full=ATP-binding cassette sub-family C member 2) HSP 1 Score: 693.73 bits (1789), Expect = 0.000e+0 Identity = 424/1247 (34.00%), Postives = 688/1247 (55.17%), Query Frame = 0
Query: 10 VLLVSQFFRAVTFGVNFVIGVHTAQRVLGALQYLAYSKLLRLA--APNEAALGQLMTFFTGDQERITEGVIVGTLFLGTPILFIMSASYATYLVGPLSLVGLLIILLFYPVMGIIATLTSKLRLRIVNVTDKRTTQMNEILNSIRLIKMYAWEKSFEDRVHKIRAHEIKELRKAAFLQSSFTSITPSVTIIATIVTF--FTLTASGYDLTAPEAFTVFSIFVSLQFTVGTLPYALKCLAEAKVSLVRLQKFMSLPEYMHPSSRNFNPDDPKNLRIQIQNANLGWTKAPEWETEDEKKKSKVTNKKKKAEKGSKDEAEVLKPKYEELSYTPCLFDINLTVEEGSLIGVAGPIGAGKSSLLSAIMGEMKQLTGDFKIRGRMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKARGKTVLLVSHGMQFLEKCDSVIYVSNGKIIERGTHKELMEQTEGQYLHMSTF-DQSHKASRTRGYSESLEQ-------PTLDEKVDDRKGSLTKRHASI---------------------------VSGSADETDQAKGAFTVEEGDVENA--GWGVLYRYFQACGGLFIMFLLFLAILAFALARLFTSVWLQIWLDNGDGLEQERMDNMTLYNMTYSDSEIKGFVTHNPDLWFYQTIYFVNLAIMVVIGLIKGIVLAFQFLKGSSK-LHDAMLHRVMRSPMKFFDTTPSGRILNRFSKDMDELDVRMPFFTEFVCQSVLFC----VTQISVVCFVYPYFMVPFGVILVVFCVLDVIMNRGILETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQTCTFVPFVMRMKADFRARFNSVERVAEYATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMKSVQMD 1210
V L+ FF F FV+G+ ++ ++ Y K L L+ A + +G+ + + D +++ + L + + +S + +GP L G+ +++L PV G++AT K++++ + DKR MNEIL+ I+++K +AWE SF+++V+ IR E++ L + + LQ+ I + +++TF + L S L A +AFT ++F L+F + LP + + +A VS+ RL++++ + + R+ D +Q A+ W + E +D +NL ++ G L+ V G +G+GKSSL+SA++GEM+ + G I+G +A V QQAWI NGT+++NIL G+ Y++++YQ VI ACAL DLE+L GD+ EIGE+G+NLSGGQK RV+LARA Y D DIY+LDDPLSAVD V K IF + + GKT +LV+HG+ FL + D ++ + G I+E+G++ +LM++ + TF S ++S E+ PT++E DD SLT R + V+ + + KG +++ VE + + +Y QA G ++F++ +L + +A + T++WL W SDSE + ++P + F L I I L+ + + + +SK LH +L ++R+PM FFDTTP+GRI+NRF+ D+ +D +P +S L C V+ + ++C P F++ + +++ + V + ++L++VTKSP+ H S ++G+ +IR ++ Q F ++ ++ + + +NRW R+++VG L + +A V++K S++ G L+N + +++RM ++ +VER+ EY +++ EAP ++ +KKP + WP+ G I F + +RYR +L LVL I+ +I EKVG+VGRTGAGK+SL L R+ E G I+ID + IA IGLHDLR + +IPQDP+LF G LR N+DPF++Y+D +IW ALE +HLK+ ++G Q L V GDN S+G++QL+CL RA+LRK+K+L+LDEATA+VD++TD LIQ TI+ FS+CTV+T+AHRLHT+++ D+I+V+ SG+IVE GSP+ELLSN G F M K ++
Sbjct: 368 VTLIQSFFLQCYFQFCFVLGMTVRTTIIASV----YKKALTLSNLARRQYTIGETVNLMSVDSQKLMDVTNYIHLLWSSVLQIALSIFFLWRELGPSILAGVGLMVLLVPVNGVLATKIRKIQVQNMKNKDKRLKIMNEILSGIKILKYFAWEPSFKEQVNSIRKKELRNLLRFSQLQTILIFILHLTPTLVSVITFSVYVLVDSQNVLNAEKAFTSITLFNILRFPLAMLPMVISSVIQASVSVDRLEQYLGSDDLDLSAIRHVCHFDKA---VQFSEASFTWDRDLEATIQD----------------------------------------VNLDIKPGQLVAVVGTVGSGKSSLISAMLGEMENVHGHITIKGSIAYVPQQAWIQNGTIKDNILFGSEYDEKKYQRVIEACALLPDLEMLPGGDMAEIGEKGINLSGGQKHRVSLARATYQDADIYILDDPLSAVDTHVGKHIFNKVVGPNGLLSGKTRILVTHGIHFLPQVDEIVVLGKGTILEKGSYSDLMDKKGVFAKNWKTFMKHSGPEGEATVDNDSEEEDGDCGLIPTVEEIPDD-AASLTMRRENSLRRTLSRSSRSGSRRGKSLKSSLKIKSVNALNKKEEVVKGQKLIKKEFVETGKVKFSIYLKYLQAVGWWSLLFIVIFYVLNY-VAFIGTNLWLSAWT---------------------SDSEKQNGTDNSPSQRDMRIGVFGALGIAQGIFLLSSSLWSIYACRNASKTLHRQLLTNILRAPMSFFDTTPTGRIVNRFAGDISTVDDTLP----QTLRSWLLCFFGIVSTLVMICMATPIFIIIIIPLSILYVSVQVFYVATSRQLRRLDSVTKSPIYSHFSETVSGLPVIRAFEHQQRFLANSEKQIDTNQKCVFSWITSNRWLAIRLELVGNLIVFCSALLLVIYKNSLTGDTVGFVLSNALNITQTLNWLVRMTSEVETNIVAVERINEY-INVDNEAP-WVTDKKPPADWPKKGEIQFNNYQVRYRPELDLVLKGITCNIKSTEKVGVVGRTGAGKSSLTNCLFRILE-SAGGQIIIDGIDIASIGLHDLRGRLTIIPQDPILFSGNLRMNLDPFNKYSDEEIWRALELAHLKSFVAGLQLGLLHEVTEGGDNLSIGQRQLLCLGRAVLRKSKILVLDEATAAVDLETDSLIQTTIRNEFSQCTVITIAHRLHTIMDSDKIMVLDSGKIVEYGSPEELLSNM-GPFYLMAKEAGIE 1536 HSP 2 Score: 89.7373 bits (221), Expect = 1.141e-16 Identity = 114/496 (22.98%), Postives = 221/496 (44.56%), Query Frame = 0
Query: 746 GRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMVPFGVILVVFCVLDVIMNRGILETK----KLENV-TKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKG----SVSPAIAGLALANVFQ-TCTFVPFVMRMKADFRARFNSVERVAEY--ATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATI---KEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFT----SMMKSVQMDHQASPVREAEEE 1222
G +N S D +L + + + + SVL QI++ F + P + V VL V +N G+L TK +++N+ K + ++ ++GI I++ + + F+++ + L + +F + + L V+T + V+ + A + L N+ + +P V+ + +A SV+R+ +Y + DL+ A ++ A + F + S + +DL + +++DI G+ V +VG G+GK+SL++ + L E+E VH G ++ +IA +PQ + GT++ N+ +Y + + +E L + + +G N S G+K + L RA + + +LD+ ++VD I + S T + V H +H + D I+V+ G I+E GS +L+ ++ GVF + MK + +A+ ++EEE
Sbjct: 416 GETVNLMSVDSQKL-MDVTNYIHLLWSSVL----QIALSIFFLWRELGPSILAGVGLMVLLVPVN-GVLATKIRKIQVQNMKNKDKRLKIMNEILSGIKILKYFAWEPSFKEQVNSIRKKELRNLLRFSQLQTILIFILHLTPTLVSVITFSVYVLVDSQNVLNAEKAFTSITLFNILRFPLAMLPMVI--SSVIQASV-SVDRLEQYLGSDDLDLSAIRHVCHFDKA--------VQFSEASFTWDRDLEATIQDVNLDIKPGQLVAVVGTVGSGKSSLISAM--LGEME--------NVH----GHITIKGSIAYVPQQAWIQNGTIKDNILFGSEYDEKKYQRVIEACALLPDLEMLPGGDMAEIGEKGINLSGGQKHRVSLARATYQDADIYILDDPLSAVDTHVGKHIFNKVVGPNGLLSGKTRILVTHGIHFLPQVDEIVVLGKGTILEKGSYSDLM-DKKGVFAKNWKTFMKHSGPEGEATVDNDSEEE 879
BLAST of multidrug resistance-associated protein 5 vs. SwissProt
Match: gi|218526606|sp|B2RX12.1|MRP3_MOUSE (RecName: Full=Canalicular multispecific organic anion transporter 2; AltName: Full=ATP-binding cassette sub-family C member 3; AltName: Full=Multidrug resistance-associated protein 3) HSP 1 Score: 683.33 bits (1762), Expect = 0.000e+0 Identity = 415/1244 (33.36%), Postives = 659/1244 (52.97%), Query Frame = 0
Query: 11 LLVSQFFRAVTFGVNFVIGVHTAQRVLGALQYLAYSKLLRL--AAPNEAALGQLMTFFTGDQERITEGVIVGTLFLGTPILFIMSASYATYLVGPLSLVGLLIILLFYPVMGIIATLTSKLRLRIVNVTDKRTTQMNEILNSIRLIKMYAWEKSFEDRVHKIRAHEIKELRKAAFLQSSFTSITPSVTIIATIVTF--FTLTASGYDLTAPEAFTVFSIFVSLQFTVGTLPYALKCLAEAKVSLVRLQKFMSLPEYMHPSSRNFNPDDPKNLRIQIQNANLGWTKAPEWETEDEKKKSKVTNKKKKAEKGSKDEAEVLKPKYEELSYTPCLFDINLTVEEGSLIGVAGPIGAGKSSLLSAIMGEMKQLTGDFKIRGRMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKARGKTVLLVSHGMQFLEKCDSVIYVSNGKIIERGTHKELMEQ--TEGQYLHMSTFDQS---HKASRTRGYSESL----------------------------EQPTLDEKVDDRKGSLTKRHASIVSGSADETD-QAKGAFTVEE-GDVENAGWGVLYRYFQACGGLFIMFLLFLAILAFALARLFTSVWLQIWLDNGDGLEQERMDNMTLYNMTYSDSEIKGFVTHNPDLWFYQTIYFVNLAIMVVIGLIKGIVL---AFQFLKGSSK----LHDAMLHRVMRSPMKFFDTTPSGRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMV---PFGVILVVFCVLDVIMNRGILETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQTCTFVPFVMRMKADFRARFNSVERVAEYATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMK 1205
L++ Q++ + FV+ + ++G + Y K L + + E+ +G+++ + D +R + L P+ I++ + ++GP +L G+ +I+L P+ G ++ +++ + D R M+EILN I+++K+YAWE SF ++V IR E++ LRK A+LQ+ T I + T++T + L A +AF S+F L+ + LP + L +A VSL R+Q F++ E + P P I I N W + P L +N+ + +G+L+ V GP+G GKSSL+SA++GEM++L G ++G +A V QQAWI N T++EN+L G +RYQ + CAL DL++L GD TEIGE+G+NLSGGQ+QRV+LARA+Y+D +I+LLDDPLSAVD+ VAK IF + I + GKT +LV+HG+ FL + D +I ++ G++ E G + L++ + +L D+ H+A+ E L E +L + + + ++ K+H + + A T + GA EE + N V + Y ++ G L + L + A + +VWL W ++ E+ N T V L + +G+++G+++ AF + G+ + LH+A+LH +RSP FFDTTPSGRILNRFSKD+ +D + + S ++ I V+ P FMV P V+ V +R + K+LE++++SP+ H S + G ++IR Y R F+ D ++ + ++ Y +NRW ++ VG ++ A F+V+ + S++P + GL+++ Q + +++RM +D + +VERV EY+ + EAP + + WP G + F++ S+RYR L LVL +++ + GGEKVGIVGRTGAGK+S+ L R+ E G IVID +++A IGLHDLRS + +IPQDP+LF GTLR N+DPF +Y++ IW ALE SHL +S L GDN SVG++QL+CL RALLRK++VL+LDEATA++D++TD LIQ TI+ F CTVLT+AHRL+T+++Y+R++V+ G + E SP L++ G+F M K
Sbjct: 364 LILHQYYHCI-----FVMALRLRTAIIGVI----YRKALVITNSVKRESTVGEMVNLMSVDAQRFMDVSPFINLLWSAPLQVILAIYFLWQILGPSALAGVAVIVLLIPLNGAVSMKMKTYQVKQMKFKDSRIKLMSEILNGIKVLKLYAWEPSFLEQVKGIRQSELQLLRKGAYLQAISTFIWICTPFLVTLITLGVYVYVDESNVLDAEKAFVSLSLFNILKIPLNMLPQLISGLTQASVSLKRIQDFLNQNE-LDPQCVERKTISP-GYAITIHNGTFTWAQ----------------------------------------DLPPTLHSLNIQIPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGVVSVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLAGGQVSEMGHYSALLQHDGSFANFLRNYAPDEDQEDHEAALQNANEEVLLLEDTLSTHTDLTDNEPAIYEVRKQFMREMSSLSSEGEVQNRTMPKKHTNSLEKEALVTKTKETGALIKEEIAETGNVKLSVYWDYAKSMG-LCTTLSICLLYGGQSAAAIGANVWLSAWSNDA---EEHGQQNKT----------------------------SVRLGVYAALGILQGLLVMLSAFTMVVGAIQAARLLHEALLHNKIRSPQSFFDTTPSGRILNRFSKDIYVIDEVLAPTILMLLNSFFTSISTIMVIVASTPLFMVVVLPLAVLYGFVQRFYVATSR---QLKRLESISRSPIFSHFSETVTGTSVIRAYGRIQDFKVLSDTKVDNNQKSSYPYIASNRWLGVHVEFVGNCVVLFAALFAVIGRNSLNPGLVGLSVSYALQVTMALNWMIRMISDLESNIIAVERVKEYSKT-KTEAPWVVESNRAPEGWPTRGMVEFRNYSVRYRPGLELVLKNVTVHVQGGEKVGIVGRTGAGKSSMTLCLFRILE-AAEGEIVIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGRYSEEDIWRALELSHLNTFVSSQPAGLDFQCAEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDLETDDLIQGTIRTQFEDCTVLTIAHRLNTIMDYNRVLVLDKGVVAEFDSPVNLIA-AGGIFYGMAK 1518 HSP 2 Score: 88.1965 bits (217), Expect = 3.219e-16 Identity = 116/503 (23.06%), Postives = 217/503 (43.14%), Query Frame = 0
Query: 746 GRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMV--PFGVILVVFCVLDVIMNRGI---LETKKLENVT-KSPVIHHLSSAMAGITIIRGYQRQSVF--QKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGSV---SPAIAGLALANVFQTCTFVPFVM--RMKADFRARFNSVERVAEYATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVD--VKTDFLIQATIKEA-FSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMKSV-----QMDHQASPVREAEEELVRDD 1227
G ++N S D PF L + V+ +Y + + P + V VL + +N + ++T +++ + K I +S + GI +++ Y + F Q + R + L Y A F++ + ++T++ + V + +V A L+L N+ + +P M ++ + S++R+ ++ E + P+ + K + + AIT + + + QDLP L+ +++ I G V +VG G GK+SLV+ L L E+E +V ++ ++A +PQ + TL+ NV + ALE L A + + +G N S G++Q + L RA+ + LLD+ ++VD V Q E + T + V H + + D IIV+ G++ E+G LL + +G F + +++ Q DH+A+ EE L+ +D
Sbjct: 406 GEMVNLMSVDAQRFMDVSPFIN-------LLWSAPLQVILAIYFLWQILGPSALAGVAVIVLLIPLNGAVSMKMKTYQVKQMKFKDSRIKLMSEILNGIKVLKLYAWEPSFLEQVKGIRQSELQLLRKGAYLQAISTFIW-ICTPFLVTLITLGVYVYVDESNVLDAEKAFVSLSLFNILK----IPLNMLPQLISGLTQASVSLKRIQDFLNQNELD-PQCVERKTISPGY----AITIHNGTFTWAQDLPPTLHSLNIQIPKGALVAVVGPVGCGKSSLVSAL--LGEMEKLEGVV------------SVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLAGGQVSEMGHYSALLQH-DGSFANFLRNYAPDEDQEDHEAALQNANEEVLLLED 876
BLAST of multidrug resistance-associated protein 5 vs. SwissProt
Match: gi|6016599|sp|O88563.1|MRP3_RAT (RecName: Full=Canalicular multispecific organic anion transporter 2; AltName: Full=ATP-binding cassette sub-family C member 3; AltName: Full=MRP-like protein 2; Short=MLP-2; AltName: Full=Multidrug resistance-associated protein 3) HSP 1 Score: 681.404 bits (1757), Expect = 0.000e+0 Identity = 416/1252 (33.23%), Postives = 659/1252 (52.64%), Query Frame = 0
Query: 3 YGWTLVLVLLVSQFFRAVTFGVNFVIGVHTAQRVLGALQYLAYSKLLRL--AAPNEAALGQLMTFFTGDQERITEGVIVGTLFLGTPILFIMSASYATYLVGPLSLVGLLIILLFYPVMGIIATLTSKLRLRIVNVTDKRTTQMNEILNSIRLIKMYAWEKSFEDRVHKIRAHEIKELRKAAFLQSSFTSITPSVTIIATIVTF--FTLTASGYDLTAPEAFTVFSIFVSLQFTVGTLPYALKCLAEAKVSLVRLQKFMSLPEYMHPSSRNFNPDDPKNLRIQIQNANLGWTKAPEWETEDEKKKSKVTNKKKKAEKGSKDEAEVLKPKYEELSYTPCLFDINLTVEEGSLIGVAGPIGAGKSSLLSAIMGEMKQLTGDFKIRGRMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKARGKTVLLVSHGMQFLEKCDSVIYVSNGKIIERGTHKELMEQ--TEGQYLHMSTFDQSHKASR---TRGYSESL----------------------------EQPTLDEKVDDRKGSLTKRHASIVSGSADETD-QAKGAFTVEE-GDVENAGWGVLYRYFQACGGLFIMFLLFLAILAFALARLFTSVWLQIWLDNGDGLEQERMDNMTLYNMTYSDSEIKGFVTHNPDLWFYQTIYFVNLAIMVVIGLIKGIVL---AFQFLKGSSK----LHDAMLHRVMRSPMKFFDTTPSGRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMV---PFGVILVVFCVLDVIMNRGILETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQTCTFVPFVMRMKADFRARFNSVERVAEYATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMK 1205
+G+ L ++ VS + + ++ A R+ A+ + Y K L + + E +G+++ + D +R + L P+ I++ + ++GP +L G+ +I+L P+ G ++ +++ + D R M+EILN I+++K+YAWE +F ++V IR E++ LRK A+LQ+ T I + T++T + L A +AF S+F L+ + LP + + + VSL R+Q F++ E + P P I I N W+K P L IN+ + +G+L+ V GP+G GKSSL+SA++GEM++L G ++G +A V QQAWI N T++EN+L G +RYQ + CAL DL++L GD TEIGE+G+NLSGGQ+QRV+LARA+Y+D +I+LLDDPLSAVD+ VAK IF + I + GKT +LV+HG+ FL + D +I +++G+I E G + EL++ + +L D++ +A+ E L E +L + + + + KR+ S + T + GA EE + N V + Y ++ G +F+ L A+A + +VWL W ++ + E + +N + V L + +G+++G+++ AF + G+ + LH A+LH +R+P FFDTTPSGRILNRFSKD+ + + + S ++ I V+ P F V P V V +R + K+LE+V++SP+ H S + G ++IR Y R F+ D ++ + T Y +NRW ++ VG ++ +A F+V+ + S++P + GL+++ Q + +++R +D + +VERV EY+ E EAP + + WP G + F++ S+RYR L LVL +++ + GGEKVGIVGRTGAGK+S+ L R+ E G I ID +++A IGLHDLRS + +IPQDP+LF GTLR N+DPF +Y+D IW LE SHL A +S L GDN SVG++QL+CL RALLRK++VL+LDEATA++D++TD LIQ TI+ F CTVLT+AHRL+T+++Y+R++V+ G + E SP L++ G+F M K
Sbjct: 346 WGFLLAGLMFVSSTMQTLILHQHYHCIFVMALRIRTAIIGVIYRKALTITNSVKREYTVGEMVNLMSVDAQRFMDVSPFINLLWSAPLQVILAIYFLWQILGPSALAGVAVIVLLIPLNGAVSMKMKTYQVQQMKFKDSRIKLMSEILNGIKVLKLYAWEPTFLEQVEGIRQGELQLLRKGAYLQAISTFIWVCTPFMVTLITLGVYVCVDKNNVLDAEKAFVSLSLFNILKIPLNLLPQLISGMTQTSVSLKRIQDFLNQDE-LDPQCVERKTISPGR-AITIHNGTFSWSK----------------------------------------DLPPTLHSINIQIPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGAVSVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQITEMGHYSELLQHDGSFANFLRNYAPDENQEANEGVLQHANEEVLLLEDTLSTHTDLTDTEPAIYEVRKQFMREMSSLSSEGEGQNRPVLKRYTSSLEKEVPATQTKETGALIKEEIAETGNVKLSVYWDYAKSVGLCTTLFICLLYAGQNAVA-IGANVWLSAWTNDVE--EHGQQNNTS-----------------------------VRLGVYATLGILQGLLVMLSAFTMVVGAIQAARLLHTALLHNQIRAPQSFFDTTPSGRILNRFSKDIYVIHEVLAPTILMLFNSFYTSISTIVVIVASTPLFCVVVLPLAVFYGFVQRFYVATSR---QLKRLESVSRSPIFSHFSETVTGTSVIRAYGRVQDFKVLSDAKVDSNQKTTYPYIASNRWLGVHVEFVGNCVVLFSALFAVIGRNSLNPGLVGLSVSYALQVTLSLNWMIRTLSDLESNIIAVERVKEYSKT-ETEAPWVLESNRAPEGWPRSGVVEFRNYSVRYRPGLELVLKNLTLHVQGGEKVGIVGRTGAGKSSMTLCLFRILE-AAEGEIFIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGRYSDEDIWRTLELSHLSAFVSSQPTGLDFQCSEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDLETDDLIQGTIRTQFEDCTVLTIAHRLNTIMDYNRVLVLDKGVVAEFDSPVNLIA-AGGIFYGMAK 1517 HSP 2 Score: 86.2705 bits (212), Expect = 1.236e-15 Identity = 117/496 (23.59%), Postives = 216/496 (43.55%), Query Frame = 0
Query: 746 GRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMV--PFGVILVVFCVLDVIMNRGI---LETKKLENVT-KSPVIHHLSSAMAGITIIRGYQRQSVFQKRFD--RDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGSV---SPAIAGLALANVFQTCTFVPFVM--RMKADFRARFNSVERVAEYATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVD--VKTDFLIQATIKEA-FSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMKSVQMDHQASPVREAEEELVR 1225
G ++N S D PF L + V+ +Y + + P + V VL + +N + ++T +++ + K I +S + GI +++ Y + F ++ + R + L Y A F++ M+T++ + V K +V A L+L N+ + +P + ++ + S++R+ ++ E + P+ + E+K S AIT + + + +DLP L+ I++ I G V +VG G GK+SLV+ L L E+E K+ G ++ ++A +PQ + TL+ NV + ALE L A + + +G N S G++Q + L RA+ + LLD+ ++VD V Q E + T + V H + + D IIV+ G+I E+G ELL + +G F + +++ D +EA E +++
Sbjct: 405 GEMVNLMSVDAQRFMDVSPFIN-------LLWSAPLQVILAIYFLWQILGPSALAGVAVIVLLIPLNGAVSMKMKTYQVQQMKFKDSRIKLMSEILNGIKVLKLYAWEPTFLEQVEGIRQGELQLLRKGAYLQAISTFIWVCTPF-MVTLITLGVYVCVDKNNVLDAEKAFVSLSLFNILK----IPLNLLPQLISGMTQTSVSLKRIQDFLNQDELD-PQCV-ERKTISP---GRAITIHNGTFSWSKDLPPTLHSINIQIPKGALVAVVGPVGCGKSSLVSAL--LGEME--------KLE----GAVSVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQITEMGHYSELLQH-DGSFANFLRNYAPDEN----QEANEGVLQ 864
BLAST of multidrug resistance-associated protein 5 vs. nr
Match: gi|499044060|ref|XP_004572630.1| (multidrug resistance-associated protein 5 isoform X1 [Maylandia zebra]) HSP 1 Score: 935.25 bits (2416), Expect = 0.000e+0 Identity = 498/1240 (40.16%), Postives = 737/1240 (59.44%), Query Frame = 0
Query: 14 SQFFRAVTFGVNFVIGVHTAQRVLGALQYLAYSKLLRLAAPNEAALGQLMTFFTGDQERITEGVIVGTLFLGTPILFIMSASYATYLVGPLSLVGLLIILLFYPVMGIIATLTSKLRLRIVNVTDKRTTQMNEILNSIRLIKMYAWEKSFEDRVHKIRAHEIKELRKAAFLQSSFTSITPSVTIIATIVTFFTLTASGYDLTAPEAFTVFSIFVSLQFTVGTLPYALKCLAEAKVSLVRLQKFMSLPEYMHPSSRNFNPDDPKNLRIQIQNANLGWTKAPEWETEDEKKKSKVTNKKKKAEKGSKDEAEVLKPKYEE-----------------------------LSYTPC--------LFDINLTVEEGSLIGVAGPIGAGKSSLLSAIMGEMKQLTGDFKIRGRMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKARGKTVLLVSHGMQFLEKCDSVIYVSNGKIIERGTHKELMEQTEGQYLHMSTF----DQSHKASRTRGYSESLEQPTLDEKVDDRKGSLTKRHASIVSGSADETDQAKGAFTVEEGDVENAGWGVLYRYFQACGG----LFIMFLLFLAILAFALARLFTSVWLQIWLDNGDGLEQERMDNMTLYNMTYSDSEIKGFVTHNPDLWFYQTIYFVNLAIMVVIGLIKGIVLAFQFLKGSSKLHDAMLHRVMRSPMKFFDTTPSGRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMVPFGVILVVFCVLDVIMNRGILETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQTCTFVPFVMRMKADFRARFNSVERVAEYATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMKSVQ 1208
++ R+ + + + + T R+ GA+ LA+ K+LRL + + ++GQL+ + D +R+ E VG+L G P++ ++ +Y +++GP SL+G + +LFYP M + + +T+ R + + VTD+R +MNEIL+ I+ IKMYAW K+F VH+IR E + L + QS + P V +IA++ TF GYDLTA +AFTV ++F ++ F + P+++K L+EA V++ R + LPE + NP + ++I A+L W E + + V + ++ ++ V++ + EE L TP L +INL++++G L+GV G +G+GK+SL+SAI+G+M L G ++GR+A V+QQAWI N T+R+NIL G Y+++R+Q VI AC L TDL LL + DLTEIGERG NLSGGQ+QR++LARALY+D D+Y+LDDPLSA+D VA IF I QL R KTV+ V+H +Q+L CD VI + G I+E+G H LM+ + G Y M D+ H + +R S +P D + GSL K++ +V + +E Q GA W V Y ACGG L I+ L L + + A F WL W++ G G + N + +++ D NP + Y IY ++ +M++ LI+G+ L+ SSKLHD + H+++R PMKFFDTTP+GR+LNRFSKDMDE+D R+PF E Q+V+ + V+ V+P+F+V G ++++F VL I I E K+L+NVT SP + H++S++ G+ ++ Y R F R+ L+ + + L+ A RW R+DI+ + I +TA VV G +SPA AGLA++ Q F +R+ ++ ARF SVER+ Y L QEAP + + P WP+ G + KDV +RY+++LPLVLNKIS I EKVGIVGRTG+GK+SL L RL E GSI+ID V I++IGL DLRS +++IPQDPVLF GT+RSN+DPF+QY++ +IW ALE+SH+K +S +L V G+NFSVGE+QL+C+ RALLR+ KVL+LDEATA++D + D LIQ TI+ +F CT LT+AHRLHTV+ DRI+V+ G++VE P +LL+N N SM+ +V+
Sbjct: 186 AELVRSWSLALTWALNYRTGTRLRGAILSLAFQKILRLRSIRDKSVGQLVNMCSSDGQRMFEAAAVGSLLAGGPLVAVLGVAYNLFILGPTSLLGSAVFILFYPTMMLSSRMTAYFRRKGMAVTDRRVQKMNEILSYIKFIKMYAWVKAFSQDVHRIRDEERRILELTGYFQSITVGVAPIVVVIASVATFSAHMLLGYDLTAAQAFTVVTVFNAMTFALKVTPFSVKSLSEASVAVERFKSLFLLPEVDGVRALPVNP----QVAVEISGASLAW----EGGGQSAQPSPSVGGASRHRQREKCRDSAVIQEQDEEEVKDSLLRGREGGEERSPEEEEDGEACPPLLPTPSIPQRLQSTLHNINLSIQQGKLLGVCGSVGSGKTSLVSAILGQMTVLEGSVAVKGRLAYVAQQAWILNATLRDNILFGLEYQEDRFQSVISACCLRTDLALLPSADLTEIGERGANLSGGQRQRISLARALYSDRDVYILDDPLSALDTHVASHIFHNAIRKQL--RHKTVIFVTHQLQYLVDCDDVILMREGSIVEQGNHDNLMKLS-GDYAAMFNLFLLGDKPHIEAPSRKNGSSQRKPA-----DAKPGSL-KKNIPVVKDNGEE--QQYGAVV----------WPVFQVYMSACGGSASCLLIVALFVLNVGSSA----FCHWWLSYWINQGSGNTTVTLGNSSAVSISMRD---------NPMMQQYAAIYASSMGVMLLFKLIRGVAFVKGTLRASSKLHDELFHKILRCPMKFFDTTPTGRLLNRFSKDMDEVDTRLPFQAEMFIQNVILVFFCLGVISCVFPWFLVAVGPLVLLFAVLHSISRVFIRELKRLDNVTMSPFMSHITSSIHGLATLQAYDRGRDFLHRYQVLLDQNQAPFYLFSCAMRWLAVRLDIISVALISITALMMVVMHGKISPAYAGLAISYAVQLTGLFQFTVRLASETEARFTSVERIHHYIQSLSQEAPARVKGRAPPPDWPQEGELVMKDVEMRYQENLPLVLNKISCTIRPKEKVGIVGRTGSGKSSLGVALFRLVEC-CGGSILIDGVDISDIGLADLRSKLSIIPQDPVLFSGTVRSNLDPFNQYSEEKIWDALERSHMKECVSQLPLKLESEVVENGENFSVGERQLLCMARALLRRCKVLILDEATAAMDAEMDALIQETIRSSFHHCTTLTIAHRLHTVLASDRIMVLNQGQVVEFDEPSKLLANENSRLCSMLAAVE 1382
BLAST of multidrug resistance-associated protein 5 vs. nr
Match: gi|556980161|ref|XP_005996825.1| (PREDICTED: multidrug resistance-associated protein 5 isoform X1 [Latimeria chalumnae]) HSP 1 Score: 934.865 bits (2415), Expect = 0.000e+0 Identity = 493/1232 (40.02%), Postives = 738/1232 (59.90%), Query Frame = 0
Query: 1 LQYGWTLVLVLLVSQFFRAVTFGVNFVIGVHTAQRVLGALQYLAYSKLLRLAAPNEAALGQLMTFFTGDQERITEGVIVGTLFLGTPILFIMSASYATYLVGPLSLVGLLIILLFYPVMGIIATLTSKLRLRIVNVTDKRTTQMNEILNSIRLIKMYAWEKSFEDRVHKIRAHEIKELRKAAFLQSSFTSITPSVTIIATIVTFFTLTASGYDLTAPEAFTVFSIFVSLQFTVGTLPYALKCLAEAKVSLVRLQKFMSLPEYMHPSSRNFNPDDPKNLRIQIQNANLGWTK-----------APEWETEDEKKKSKVTNKKKKA----EKGS--KDEAEVLKPKYEE-------LSYTPCLFDINLTVEEGSLIGVAGPIGAGKSSLLSAIMGEMKQLTGDFKIRGRMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKARGKTVLLVSHGMQFLEKCDSVIYVSNGKIIERGTHKELMEQTEGQYLHM-STF---DQSH-KASRTRGYSESLEQPTLDEKVDDRKGSLTKRHASIVSGSADETDQAKGAFTVEEGDVENAGWGVLYRYFQACGGLFIMFLLFLAILAFALARLFTSVWLQIWLDNGDGLEQERMDNMTLYNMTYSDSEIKGFVTHNPDLWFYQTIYFVNLAIMVVIGLIKGIVLAFQFLKGSSKLHDAMLHRVMRSPMKFFDTTPSGRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMVPFGVILVVFCVLDVIMNRGILETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQTCTFVPFVMRMKADFRARFNSVERVAEYATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSM 1203
LQYG LV LL+++ R+ + + + + T R+ GA+ +A+ K+L+L E +LG+L+ + D +R+ E VG+L G P++ I+ Y +GP + +G + +LFYP M + +T+ R R V VTD R +MNEIL ++ IKMYAW K+F V KIR E K L +A + QS + P V +IA+++TF G+DLTA +AFTV ++F ++ F + P+++K L+EA V++ R + + E R P P+N I++ N L W P+ + + + KK+K+ ++ ++ +KG D + P E L L +I+ +++G L+G+ G +G+GK+SL+SA++G+M L G + G A V+QQAWI N TV++NIL G +ERY V+ C L DL +L NGDLTEIGERG NLSGGQ+QR++LARALY+D +IY+LDDPLSA+DA V IF I L++ KT+L V+H +Q+L CD VI + G IIERGTH+ELM G Y M + F D H + + + S S+++P KG+ + +S+ A T+ +EE + W V Y QA GG F+ ++ + + + F++ WL W+ G G M N T+ + + D NP + +Y IY ++ +M+V+ ++GI LK SS+LHD + R++RSPMKFFDTTP+GRILNRFSKDMDE+DVR+PF E Q+++ V + V+ V+P+F+V G ++++F +L ++ I E K+L+N+T+SP + H++S++ GI+ I Y + F ++ L+ + + L+ A RW R+D++ + I T V+ G + PA AGLA++ Q F +R+ ++ ARF SVER+ Y L EAP I K P ++WP+ G I F+D +RYR++LPLVL K+S + EK+GIVGRTG+GK+SL L RL E+ GS+ ID V+I EIGL DLRS +++IPQ+PVLF GT+RSN+DPF+QY++ QIW AL+++H+K I+ +L V GDNFSVGE+QLIC+ RALLR K+L+LDEATA++D +TD LIQ T++E+F+ CT+LT+AHRLHTV+N DRI+V+ G++VE P LL N N F +M
Sbjct: 217 LQYGLLLVFGLLITEVVRSWSLALTWALNYRTGARLRGAILTMAFQKILKLKNIKEKSLGELINVCSNDGQRMFEAAAVGSLLAGGPVVAILGMVYNVIALGPTAFLGSAVFILFYPAMMAASRVTAYFRRRCVVVTDARVQKMNEILTYVKFIKMYAWVKAFSQDVLKIREEERKILERAGYFQSITVGVAPIVVVIASVLTFSIHMLLGFDLTAAQAFTVVTVFNAMTFALKVTPFSVKSLSEASVAVDRFKSLFLMEEVHIIKKR---PMSPQN-AIELTNTTLAWDSSYSSTQSSPKMTPKLKRDGKGKKTKLQHEGQQEMLAEQKGHLLVDSDDHPSPGEENKGIHIASLRLQRALHNIDFCIQKGKLVGICGSVGSGKTSLISAVLGQMTLLEGSIAVSGNFAYVAQQAWILNATVKDNILFGKDVNEERYNRVLSVCCLRPDLAILPNGDLTEIGERGANLSGGQRQRISLARALYSDQEIYILDDPLSALDAHVGNHIFNNAIKKHLQS--KTILFVTHQLQYLVDCDEVILMKEGCIIERGTHEELM-HLNGDYAAMFNNFQLGDAPHIEINNKKNTSNSIKKP-------QEKGA---KASSVKEKPA--TNGEGQLMQLEEKGKGSVPWSVYGAYIQAAGGPFVFLIIMILFVLNVGSTAFSNWWLSYWIKQGSGNTTVLMGNDTIVSNSMKD---------NPHMRYYAGIYTFSMVVMLVLKTVRGIAFVKGTLKASSRLHDELFRRILRSPMKFFDTTPTGRILNRFSKDMDEVDVRLPFQAEMFIQNIILVVFCLGVISSVFPWFLVVVGPLVILFTLLHMVSRVFIRELKRLDNITQSPFLSHITSSIQGISTIHAYNKGPEFLHKYQELLDDNQAPFYLFSCAMRWLAVRLDVISISLITTTGLMIVLMHGQIPPAYAGLAISYAVQLTGLFQFTVRLSSETEARFTSVERIDHYIKTLTLEAPARIKNKSPPAAWPQEGEIVFEDAEMRYRENLPLVLKKVSFTVKPKEKIGIVGRTGSGKSSLGMALFRLVELS-RGSVKIDGVNIGEIGLADLRSKLSIIPQEPVLFSGTVRSNLDPFNQYSEEQIWDALDRTHMKDCIAQMPLKLESEVVENGDNFSVGERQLICVARALLRHCKILILDEATAAMDTETDSLIQETVRESFADCTMLTIAHRLHTVLNCDRIMVLNQGQVVEFDKPSVLLHNENSRFCAM 1419
BLAST of multidrug resistance-associated protein 5 vs. nr
Match: gi|1110931222|ref|XP_019203042.1| (PREDICTED: multidrug resistance-associated protein 5 isoform X1 [Oreochromis niloticus] >gi|1110931224|ref|XP_019203046.1| PREDICTED: multidrug resistance-associated protein 5 isoform X1 [Oreochromis niloticus]) HSP 1 Score: 933.324 bits (2411), Expect = 0.000e+0 Identity = 498/1237 (40.26%), Postives = 739/1237 (59.74%), Query Frame = 0
Query: 14 SQFFRAVTFGVNFVIGVHTAQRVLGALQYLAYSKLLRLAAPNEAALGQLMTFFTGDQERITEGVIVGTLFLGTPILFIMSASYATYLVGPLSLVGLLIILLFYPVMGIIATLTSKLRLRIVNVTDKRTTQMNEILNSIRLIKMYAWEKSFEDRVHKIRAHEIKELRKAAFLQSSFTSITPSVTIIATIVTFFTLTASGYDLTAPEAFTVFSIFVSLQFTVGTLPYALKCLAEAKVSLVRLQKFMSLPEYMHPSSRNFNPDDPKNLRIQIQNANLGW-----TKAP----------------------EWETEDEKKKSKVTNKKKKAEKGSKDE-AEVLKPKYEELS----YTPCLFDINLTVEEGSLIGVAGPIGAGKSSLLSAIMGEMKQLTGDFKIRGRMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKARGKTVLLVSHGMQFLEKCDSVIYVSNGKIIERGTHKELMEQTEGQYLHMSTF----DQSH--KASRTRGYSESLEQPTLDEKVDDRKGSLTKRHASIVSGSADETDQAKGAFTVEEGDVENAGWGVLYRYFQACGG----LFIMFLLFLAILAFALARLFTSVWLQIWLDNGDGLEQERMDNMTLYNMTYSDSEIKGFVTHNPDLWFYQTIYFVNLAIMVVIGLIKGIVLAFQFLKGSSKLHDAMLHRVMRSPMKFFDTTPSGRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMVPFGVILVVFCVLDVIMNRGILETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQTCTFVPFVMRMKADFRARFNSVERVAEYATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSEGDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMKSVQ 1208
++ R+ + + + + T R+ GA+ LA+ K+LRL + + ++GQL+ + D +R+ E VG+L G P++ ++ +Y +++GP SL+G + +LFYP M + +T+ R + VTD+R +MNEIL+ I+ IKMYAW K+F VH+IR E + L + QS + P V +IA++ TF GYDLTA +AFTV ++F ++ F + P+++K L+EA V++ R + LPE + NP + ++I A+L W + P + E E++ K S + ++ E+ ++E EV P S L +INL++++G L+GV G +G+GK+SL+SAI+G+M L G ++GR+A V+QQAWI N T+R+NIL G Y+++RYQ V+ AC L DL LL + DLTEIGERG NLSGGQ+QR++LARALY+D D+Y+LDDPLSA+D VA IF I QL R KTV+ V+H +Q+L CD VI + G I+E+G H LM+ + G Y M D+ H S+ G S+ + D + GS+ K++ +V + +E Q GA W V Y ACGG L I+ L L + + A F WL W++ G G + N + +++ D NP + Y IY ++ +M++ LI+G+ L+ SSKLHD + H+++R PMKFFDTTP+GRILNRFSKDMDE+D R+PF E Q+V+ + V+ V+P+F+V G ++++F VL I I E K+L+NVT SP + H++S++ G+ ++ Y R F R+ L+ + + L+ A RW R+DI+ + I +TA V+ G +SPA AGLA++ Q F +R+ ++ ARF SVER+ Y L QEAP + + P +WP+ G + K+V +RY+++LPLVLNKIS I EKVGI+GRTG+GK+SL L RL E GSI+ID V I++IGL DLRS +++IPQDPVLF GT+RSN+DPF+QY++ +IW ALE+SH+K +S +L V G+NFSVGE+QL+C+ RALLR+ KVL+LDEATA++D +TD LIQ TI+ +F CT LT+AHRLHTV+ DRI+V+ G++VE P +LL+N N SM+ +V+
Sbjct: 214 AELVRSWSLALTWALNYRTGTRLRGAILSLAFQKILRLRSVRDKSVGQLVNMCSSDGQRMFEAAAVGSLLAGGPLVAVLGVAYNLFILGPTSLLGSTVFILFYPTMMFSSRMTAYFRRKGTAVTDRRVQKMNEILSYIKFIKMYAWVKAFSQDVHRIRDEERRILELTGYFQSITVGVAPIVVVIASVATFSAHMLLGYDLTAAQAFTVVTVFNAMTFALKVTPFSVKSLSEASVAVERFKSLFLLPEVDGVRALPTNP----QVAVEISGASLAWEGGGQSAQPSPSVGGASRHRQREKCRDSAVIQEEDEEDVKDSLLRGREGGEERSPEEEDGEVCPPLLPTPSIPQRLQSTLHNINLSIQQGKLLGVCGSVGSGKTSLVSAILGQMMVLEGSVAVKGRLAYVAQQAWILNATLRDNILFGLQYQEDRYQSVLSACCLRPDLALLPSADLTEIGERGANLSGGQRQRISLARALYSDRDVYILDDPLSALDTHVASHIFHNAIRKQL--RHKTVIFVTHQLQYLVDCDDVILMREGSIVEQGNHDNLMKLS-GDYAAMFNLFLLGDKPHIEAPSKKNGGSQR-------KSADTKPGSV-KKNIPVVKDNGEE--QQYGAVV----------WPVFQVYMSACGGSASCLLIVALFVLNVGSSA----FCHWWLSYWINQGSGNTTVTLGNSSTVSISMRD---------NPMMQQYAAIYASSMGVMLLFKLIRGVAFVKGTLRASSKLHDELFHKILRCPMKFFDTTPTGRILNRFSKDMDEVDTRLPFQAEMFIQNVILVFFCLGVISCVFPWFLVAVGPLVLLFAVLHSISRVFIRELKRLDNVTMSPFMSHITSSIHGLATLQAYDRGRDFLHRYQVLLDQNQAPFYLFSCAMRWLAVRLDIISVALISITALMMVLMHGKISPAYAGLAISYAVQLTGLFQFTVRLASETEARFTSVERIHHYIQSLSQEAPARVKGRAPPPNWPQEGKLVMKEVEMRYQENLPLVLNKISCTIRPKEKVGIIGRTGSGKSSLGVALFRLVECS-GGSILIDGVDISDIGLADLRSKLSIIPQDPVLFSGTVRSNLDPFNQYSEEKIWDALERSHMKECVSQLPLKLESEVVENGENFSVGERQLLCVARALLRRCKVLILDEATAAMDAETDALIQETIRSSFHHCTTLTIAHRLHTVLASDRIMVLNQGQVVEFDEPSKLLANENSRLCSMLAAVE 1409
BLAST of multidrug resistance-associated protein 5 vs. nr
Match: gi|542152056|ref|XP_005484930.1| (PREDICTED: multidrug resistance-associated protein 5 isoform X2 [Zonotrichia albicollis]) HSP 1 Score: 933.324 bits (2411), Expect = 0.000e+0 Identity = 501/1242 (40.34%), Postives = 746/1242 (60.06%), Query Frame = 0
Query: 1 LQYGWTLVLVLLVSQFFRAVTFGVNFVIGVHTAQRVLGALQYLAYSKLLRLAAPNEAALGQLMTFFTGDQERITEGVIVGTLFLGTPILFIMSASYATYLVGPLSLVGLLIILLFYPVMGIIATLTSKLRLRIVNVTDKRTTQMNEILNSIRLIKMYAWEKSFEDRVHKIRAHEIKELRKAAFLQSSFTSITPSVTIIATIVTFFTLTASGYDLTAPEAFTVFSIFVSLQFTVGTLPYALKCLAEAKVSLVRLQKFMSLPEYMHPSSRNFNPDDPKNLRIQIQNANLGW-------TKAPEWETEDEKKKS---------KVTNKKKKA----EKGS--KDEAEVLKPKYEE-------LSYTPCLFDINLTVEEGSLIGVAGPIGAGKSSLLSAIMGEMKQLTGDFKIRGRMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKARGKTVLLVSHGMQFLEKCDSVIYVSNGKIIERGTHKELMEQTEGQYLHMSTFDQSHKASRTRGYSESLEQPTLDEKVDDRKGSLTKRHASIVSGSADETDQAKGAFTVEEGDVENAGWGVLYRYFQACGGLFIMFLLFLAILAFAL-ARLFTSVWLQIWLDNGDGLEQERMDNMTLYNMTYSDSEIKGFVTHNPDLWFYQTIYFVNLAIMVVIGLIKGIVLAFQFLKGSSKLHDAMLHRVMRSPMKFFDTTPSGRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMVPFGVILVVFCVLDVIMNRGILETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQTCTFVPFVMRMKADFRARFNSVERVAEYATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSE----GDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMKSVQ 1208
LQY LV + +++ R+ + + + + T R+ GA+ +A+ K+L+L E +LG+L+ + D +R+ E VG+L G PI+ I+ Y ++GP +G + +LFYP M ++ LT+ R + V TD+R +MNE+LN I+ IKMYAW K F V KIR E K L +A + QS + P V +IA++VTF GYDLTA +AFTV ++F S+ F + P+++K L+EA VS+ R + + E + NP + I+++NA L W +P+ + +K K K+ N+ ++A +KG D + P+ E L L++I+L +E+G L+G+ G +G+GK+SL+SAI+G+M L G + G A V+QQAWI N T+R+NIL G Y++ERY V+ C L DL +L NGDLTEIGERG NLSGGQ+QR++LARALY+D DIY+LDDPLSA+DA V IF I LK+ KTVL ++H +Q+L CD VI++ G I ERG+H+ELM G Y +T S + T ++++ T + R + + S+ + ++ +EE + W V Y QA GG F FL+ +A+ + + F++ WL W+ G G M N T+ + + D NP + +Y IY +++A+M+++ ++G+V L+ SS+LHD + R++RSPMKFFDTTP+GRILNRFSKDMDE+DVR+PF E Q+V+ + V+ V+P+F+V G ++V+F VL V+ I E K+L+N+T+SP + H++S++ G++ I Y + F R+ L+ + + L+ A RW R+DI+ + I T V+ G + PA AGLA++ Q F +R+ ++ ARF SVER+ Y L EAP I K P WP+ G + F++ +RYR++LPLVL K+S I EK+GIVGRTG+GK+SL L RL E+ G I ID V I +IGL DLRS +++IPQ+PVLF GT+RSN+DPF+QY++ QIW ALE++H+K ++ QL M +DSE G+NFSVGE+QL+C+ RALLR+ K+L+LDEATA++D +TD LIQ TI+EAF+ CT+LT+AHRLHTV+ DRI+V+ G++VE +P LL+N N F +M + +
Sbjct: 215 LQYSLFLVFGIFMTEVVRSWSLALTWALNYRTGVRLRGAVLTMAFKKILKLKNIKEKSLGELINVCSNDGQRMFEAAAVGSLLAGGPIVAILGMVYNVIILGPTGFLGSAVFILFYPAMMFVSRLTAYFRRKCVATTDERVQKMNEVLNYIKFIKMYAWVKPFSQNVQKIREEERKILERAGYFQSITVGVAPIVVVIASVVTFSVHMILGYDLTAAQAFTVVTVFNSMTFALKVTPFSVKSLSEASVSVDRFKSLFLMEEVHMIKKKPANP----HTAIEVKNATLAWDFSHASVQSSPKLTPKVKKDKKVTKSKKEKMKLQNEGQQAVLAEQKGHLLVDSDDHHSPEEEHKMIHLVSLRLQRTLYNIDLEIEKGKLVGICGSVGSGKTSLISAILGQMTLLEGSIAVSGTFAYVAQQAWILNATLRDNILFGKDYDEERYNTVLNGCCLRPDLAILPNGDLTEIGERGANLSGGQRQRISLARALYSDRDIYILDDPLSALDAHVGNHIFNSAIRKHLKS--KTVLFITHQLQYLVDCDEVIFMKEGCITERGSHEELM-NLNGDY---ATIFNSLQLGETPHIEINIKKNTNNSL--KRPQDKSTKTGSVKKEKVVKKEEEGQLVQLEEKGKGSVPWSVYGVYIQAAGGPF-AFLIIMALFVLNVGSTAFSNWWLSFWIKQGSGNTTVTMGNETVISSSMKD---------NPHMHYYAGIYALSMAVMLILKAVRGVVFVKGTLRASSRLHDELFRRILRSPMKFFDTTPTGRILNRFSKDMDEVDVRLPFQAEMFIQNVILVFFCVGVISGVFPWFLVAVGPLIVLFTVLHVVSRVFIRELKRLDNITQSPFLSHITSSIQGLSTIHAYHKGQEFLHRYQELLDDNQAPFYLFSCAMRWLAVRLDIISIALITTTGLMIVLMHGQIPPAYAGLAISYAVQLTGLFQFTVRLASETEARFTSVERIDHYIKTLSLEAPARIKNKTPPLDWPQEGEVVFENAEMRYRENLPLVLKKVSFTIKPKEKIGIVGRTGSGKSSLGMALFRLVELS-GGCIKIDGVKINDIGLADLRSKLSIIPQEPVLFSGTVRSNLDPFNQYSEEQIWAALERTHMKECVA----QLPMKLDSEVMENGENFSVGERQLLCIARALLRRCKILILDEATAAMDTETDLLIQETIREAFADCTMLTIAHRLHTVLGCDRIMVLTQGQVVEFDTPTALLANENSRFYAMFAAAE 1429
BLAST of multidrug resistance-associated protein 5 vs. nr
Match: gi|542152054|ref|XP_005484929.1| (PREDICTED: multidrug resistance-associated protein 5 isoform X1 [Zonotrichia albicollis] >gi|929455927|ref|XP_014120961.1| PREDICTED: multidrug resistance-associated protein 5 isoform X1 [Zonotrichia albicollis]) HSP 1 Score: 933.324 bits (2411), Expect = 0.000e+0 Identity = 501/1242 (40.34%), Postives = 746/1242 (60.06%), Query Frame = 0
Query: 1 LQYGWTLVLVLLVSQFFRAVTFGVNFVIGVHTAQRVLGALQYLAYSKLLRLAAPNEAALGQLMTFFTGDQERITEGVIVGTLFLGTPILFIMSASYATYLVGPLSLVGLLIILLFYPVMGIIATLTSKLRLRIVNVTDKRTTQMNEILNSIRLIKMYAWEKSFEDRVHKIRAHEIKELRKAAFLQSSFTSITPSVTIIATIVTFFTLTASGYDLTAPEAFTVFSIFVSLQFTVGTLPYALKCLAEAKVSLVRLQKFMSLPEYMHPSSRNFNPDDPKNLRIQIQNANLGW-------TKAPEWETEDEKKKS---------KVTNKKKKA----EKGS--KDEAEVLKPKYEE-------LSYTPCLFDINLTVEEGSLIGVAGPIGAGKSSLLSAIMGEMKQLTGDFKIRGRMALVSQQAWIFNGTVRENILMGAVYEKERYQVVIRACALDTDLELLANGDLTEIGERGVNLSGGQKQRVNLARALYADMDIYLLDDPLSAVDARVAKKIFREYILTQLKARGKTVLLVSHGMQFLEKCDSVIYVSNGKIIERGTHKELMEQTEGQYLHMSTFDQSHKASRTRGYSESLEQPTLDEKVDDRKGSLTKRHASIVSGSADETDQAKGAFTVEEGDVENAGWGVLYRYFQACGGLFIMFLLFLAILAFAL-ARLFTSVWLQIWLDNGDGLEQERMDNMTLYNMTYSDSEIKGFVTHNPDLWFYQTIYFVNLAIMVVIGLIKGIVLAFQFLKGSSKLHDAMLHRVMRSPMKFFDTTPSGRILNRFSKDMDELDVRMPFFTEFVCQSVLFCVTQISVVCFVYPYFMVPFGVILVVFCVLDVIMNRGILETKKLENVTKSPVIHHLSSAMAGITIIRGYQRQSVFQKRFDRDLNIHLSATSLYRYANRWFVFRMDIVGMLTIVLTAAFSVVFKGSVSPAIAGLALANVFQTCTFVPFVMRMKADFRARFNSVERVAEYATDLEQEAPEYIPEKKPASSWPEHGAITFKDVSLRYRQDLPLVLNKISMDIAGGEKVGIVGRTGAGKTSLVTTLMRLTEIEPNGSIVIDKVHIAEIGLHDLRSAIAVIPQDPVLFQGTLRSNVDPFDQYTDAQIWTALEKSHLKAKISGAQNQLAMTVDSE----GDNFSVGEKQLICLTRALLRKNKVLLLDEATASVDVKTDFLIQATIKEAFSKCTVLTVAHRLHTVVNYDRIIVMKSGEIVEIGSPKELLSNRNGVFTSMMKSVQ 1208
LQY LV + +++ R+ + + + + T R+ GA+ +A+ K+L+L E +LG+L+ + D +R+ E VG+L G PI+ I+ Y ++GP +G + +LFYP M ++ LT+ R + V TD+R +MNE+LN I+ IKMYAW K F V KIR E K L +A + QS + P V +IA++VTF GYDLTA +AFTV ++F S+ F + P+++K L+EA VS+ R + + E + NP + I+++NA L W +P+ + +K K K+ N+ ++A +KG D + P+ E L L++I+L +E+G L+G+ G +G+GK+SL+SAI+G+M L G + G A V+QQAWI N T+R+NIL G Y++ERY V+ C L DL +L NGDLTEIGERG NLSGGQ+QR++LARALY+D DIY+LDDPLSA+DA V IF I LK+ KTVL ++H +Q+L CD VI++ G I ERG+H+ELM G Y +T S + T ++++ T + R + + S+ + ++ +EE + W V Y QA GG F FL+ +A+ + + F++ WL W+ G G M N T+ + + D NP + +Y IY +++A+M+++ ++G+V L+ SS+LHD + R++RSPMKFFDTTP+GRILNRFSKDMDE+DVR+PF E Q+V+ + V+ V+P+F+V G ++V+F VL V+ I E K+L+N+T+SP + H++S++ G++ I Y + F R+ L+ + + L+ A RW R+DI+ + I T V+ G + PA AGLA++ Q F +R+ ++ ARF SVER+ Y L EAP I K P WP+ G + F++ +RYR++LPLVL K+S I EK+GIVGRTG+GK+SL L RL E+ G I ID V I +IGL DLRS +++IPQ+PVLF GT+RSN+DPF+QY++ QIW ALE++H+K ++ QL M +DSE G+NFSVGE+QL+C+ RALLR+ K+L+LDEATA++D +TD LIQ TI+EAF+ CT+LT+AHRLHTV+ DRI+V+ G++VE +P LL+N N F +M + +
Sbjct: 216 LQYSLFLVFGIFMTEVVRSWSLALTWALNYRTGVRLRGAVLTMAFKKILKLKNIKEKSLGELINVCSNDGQRMFEAAAVGSLLAGGPIVAILGMVYNVIILGPTGFLGSAVFILFYPAMMFVSRLTAYFRRKCVATTDERVQKMNEVLNYIKFIKMYAWVKPFSQNVQKIREEERKILERAGYFQSITVGVAPIVVVIASVVTFSVHMILGYDLTAAQAFTVVTVFNSMTFALKVTPFSVKSLSEASVSVDRFKSLFLMEEVHMIKKKPANP----HTAIEVKNATLAWDFSHASVQSSPKLTPKVKKDKKVTKSKKEKMKLQNEGQQAVLAEQKGHLLVDSDDHHSPEEEHKMIHLVSLRLQRTLYNIDLEIEKGKLVGICGSVGSGKTSLISAILGQMTLLEGSIAVSGTFAYVAQQAWILNATLRDNILFGKDYDEERYNTVLNGCCLRPDLAILPNGDLTEIGERGANLSGGQRQRISLARALYSDRDIYILDDPLSALDAHVGNHIFNSAIRKHLKS--KTVLFITHQLQYLVDCDEVIFMKEGCITERGSHEELM-NLNGDY---ATIFNSLQLGETPHIEINIKKNTNNSL--KRPQDKSTKTGSVKKEKVVKKEEEGQLVQLEEKGKGSVPWSVYGVYIQAAGGPF-AFLIIMALFVLNVGSTAFSNWWLSFWIKQGSGNTTVTMGNETVISSSMKD---------NPHMHYYAGIYALSMAVMLILKAVRGVVFVKGTLRASSRLHDELFRRILRSPMKFFDTTPTGRILNRFSKDMDEVDVRLPFQAEMFIQNVILVFFCVGVISGVFPWFLVAVGPLIVLFTVLHVVSRVFIRELKRLDNITQSPFLSHITSSIQGLSTIHAYHKGQEFLHRYQELLDDNQAPFYLFSCAMRWLAVRLDIISIALITTTGLMIVLMHGQIPPAYAGLAISYAVQLTGLFQFTVRLASETEARFTSVERIDHYIKTLSLEAPARIKNKTPPLDWPQEGEVVFENAEMRYRENLPLVLKKVSFTIKPKEKIGIVGRTGSGKSSLGMALFRLVELS-GGCIKIDGVKINDIGLADLRSKLSIIPQEPVLFSGTVRSNLDPFNQYSEEQIWAALERTHMKECVA----QLPMKLDSEVMENGENFSVGERQLLCIARALLRRCKILILDEATAAMDTETDLLIQETIREAFADCTMLTIAHRLHTVLGCDRIMVLTQGQVVEFDTPTALLANENSRFYAMFAAAE 1430 The following BLAST results are available for this feature:
BLAST of multidrug resistance-associated protein 5 vs. L. salmonis genes
Analysis Date: 2018-04-19 (T. kinsejongensis vs L. Salmonis peptides) Total hits: 21
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BLAST of multidrug resistance-associated protein 5 vs. SwissProt
Analysis Date: 2018-04-19 (T. kingejongensis peptided Blastp vs. SwissProt) Total hits: 25
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BLAST of multidrug resistance-associated protein 5 vs. nr
Analysis Date: 2018-05-15 (T. kingsejongensis proteins Blastp vs. NR) Total hits: 25
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The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at scaffold605_size125465:27676..33663+ Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>maker-scaffold605_size125465-snap-gene-0.27 ID=maker-scaffold605_size125465-snap-gene-0.27|Name=multidrug resistance-associated protein 5|organism=Tigriopus kingsejongensis|type=gene|length=5988bp|location=Sequence derived from alignment at scaffold605_size125465:27676..33663+ (Tigriopus kingsejongensis)back to top Synonyms
The feature 'multidrug resistance-associated protein 5' has the following synonyms
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