multidrug resistance-associated protein 1 isoform x4, maker-scaffold81_size397536-snap-gene-2.18 (gene) Tigriopus kingsejongensis
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Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. L. salmonis genes
Match: EMLSAG00000008303 (supercontig:LSalAtl2s:LSalAtl2s503:210067:213886:1 gene:EMLSAG00000008303 transcript:EMLSAT00000008303 description:"snap_masked-LSalAtl2s503-processed-gene-2.8") HSP 1 Score: 56.6102 bits (135), Expect = 1.679e-8 Identity = 40/118 (33.90%), Postives = 59/118 (50.00%), Query Frame = 0
Query: 1556 PKRISEIVGVSERTVRNIRAAKKIGNGVERKEGSGGNGLKRNEAFLKSLEAKIKADPTASMLCLADEFDVDEITIRRAVHDDLGFTSYVRTPRHLLTDRMKATRLERCKKVLNFLKSN 1673
P I +++ TV I A +I K S + R FL+ L IKA P S+ L V + + +AV++DLG+ SY +H+LT MKATRL ++LN L+S+
Sbjct: 5 PSAIYKLLNYPNTTVYRIFNAWEIKGKFCCKAHSMRSDRIRTFRFLEGLRKSIKASPGTSLSRLVKNXGVSKQLVSKAVNEDLGYRSYRMVKQHILTASMKATRLANGMRLLNDLESH 122
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. L. salmonis genes
Match: EMLSAG00000005788 (supercontig:LSalAtl2s:LSalAtl2s3118:3124:4893:1 gene:EMLSAG00000005788 transcript:EMLSAT00000005788 description:"augustus_masked-LSalAtl2s3118-processed-gene-0.0") HSP 1 Score: 57.7658 bits (138), Expect = 2.191e-8 Identity = 49/188 (26.06%), Postives = 94/188 (50.00%), Query Frame = 0
Query: 1312 LVLKGITCDIHAGEKIGIVGRTGAGKSSLTMALFRLIEPSSGTIYIDGTDITTLGLGFLRSNITIIPQDPVLFSGTMRLNL-DPFE--IATD-----DQIWRALKLGHLSEYVSGLRYGLDQEISEGGGNLSVGQRQLVCLARALLRKTQILVLDEATAAVDLEMDDLIQTTIRQEFKDCTILTIAHR 1491
+++ + +I G++I I G + +GK+SL + L R + P+ ++G+ + F +I + Q P++ G++ N+ P E I+ D DQ+ R L HL + +Y L Q + LS G+ Q +C R + Q+++LDE+TA++ ++ ++ + TIL++ HR
Sbjct: 396 VLIDNLNLNIKTGDRILITGASSSGKTSL-LRLIRGLWPT-----VEGS------ISFFTDSIEFLSQRPLMTDGSLLQNMIYPSEXPISPDLTWFKDQLTR-FNLDHLYK-----QYDLFQYQNRWEDILSPGEMQRICFIRVFYHRPQVVLLDESTASLPTNIEAMLYEYLIITCPKITILSVGHR 565
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. SwissProt
Match: gi|218526606|sp|B2RX12.1|MRP3_MOUSE (RecName: Full=Canalicular multispecific organic anion transporter 2; AltName: Full=ATP-binding cassette sub-family C member 3; AltName: Full=Multidrug resistance-associated protein 3) HSP 1 Score: 1240.71 bits (3209), Expect = 0.000e+0 Identity = 672/1545 (43.50%), Postives = 964/1545 (62.39%), Query Frame = 0
Query: 33 FWDLNTTWFTLDPDFTHCFHQTALVYVPCGLLWLLAPLEIYWINASQSRHIRWNLINVAKCISIALCIILDVIS-LSLSLGYFG-NNTSWLSLSDILAPLIVFLTHALALILTLMNKKMGLTSSGILFTFWFVLVITSGLTFASVVR--------FGAFRTITSSWSVEQSMIYTIYFPLVVAISFLTFWADPPPVYWEVEDQVDVPSPEMYASFPSKIAFGWIDTLIKMGWQTPLNQRNIFDLNPNLTTNILTKK----WAKHEKKVR-------------------HPMRGTLKTDLIQTLARCFGVDFLIASGLQILGVLINQVFFVCCKAVPQTISLLITF-STSDEPLWRGYLYMSLLVAINMIRTLLNTQYFFIYLVLGQNVRTTLISAIYRKTFKLSASSRRQRSVGETVNLMSIDTERMNIVVGSLNNLWYAPLVILLSLYFLWGYLGPSCLAGLGMMIILIPINAWLSSRIKKYQFANMKKKDQRLETMNEVLEGIKVMKLYAWEPSFQEKIAAIRDSEVETLKKISYLGALQTFIFNSAVFLVTLVTFGTYVYLDPSNVLDAEKAFVSISYFNLMRGPLNQFPQFIIQLIQASVSHKRLDEFLNAPETDSKIIGNEPNSQ-HAVEVFNGSFAWDDTEDSSTIHGINLKIERGSLVAIVGQVGAGKSSLISAILGDMEKRTGSVNVDGTVAYVPQQAWIQNDTVRQNILFGRDHFPNIYFETVRACALVEDFTILEQGDQTEIGEKGINLSGGQKQRVSLARAVYNNRDIYLLDDPMSAVDAHVGKHIFEHVISSRTGVLKDKTRLLVTHNVTFLHETDLILVMKNGRISEMGTFNDLMSGGGDFSLFLAEYGNISEQD------AGSVEQVETFQDTLDMVSNLSQNELNKTPPDPSSPAFLDLNSPLGSTIGSVKIRKRNSAKTFRKRKGKVGPSSSNKTNSREKGKLVVEEKLETSAVSNAVYVYYAKAIGLFVTITIFGLYAVNQAFSVGTNVWLAKWSDDPQSAIPKYR-DMYLGGYGGLGGASALTVMVVYLIITIGGLNASTKLHNNLLAKILAAPMSFFDTNPKGRILNRFGKDVDAVDTNVPSNFNSICRLLFNTFGTIVVICATNPLFIVVFIPLFLAYWFIQKLYITTSRQLKRLNSIARSPIYSLFGETLSGVPTIKAFNLQDQLIKINESKVDTLQTTTYLNQAANRWLSVRLEMLGNVVILFAALFAVLGRDKVDPGEVGLSLSYATQITTFLTFLIRMMSMIENNMVSVERIQEYEDHVDQEAPYVCPMESTLEKQWPPRGAIRFQDYKTRYRPGLDLVLKGITCDIHAGEKIGIVGRTGAGKSSLTMALFRLIEPSSGTIYIDGTDITTLGLGFLRSNITIIPQDPVLFSGTMRLNLDPFEIATDDQIWRALKLGHLSEYVSGLRYGLDQEISEGGGNLSVGQRQLVCLARALLRKTQILVLDEATAAVDLEMDDLIQTTIRQEFKDCTILTIAHRLNTIMDCDRVIVLRSGLIAEMDEPQKLLQDTNSIFFGMAKNAGL 1535
FWD N + +T PD T CF + L +VPC LW P ++++ Q +I + ++ K AL ++L +S + L + G + S + + PL+V +T LA +L + G+ SSG+L FW + VI + + F S + FR T + IYF LV L+ + + PP++ E+ P PE A F S+++F W L +G++ PL R+++ L+ ++ + ++ W K + + P + + ++ L R F L+++ ++ L+ V PQ +S+LI F S P W G+L L+ + ++TL+ QY+ V+ +RT +I IYRK ++ S +R+ +VGE VNLMS+D +R V +N LW APL ++L++YFLW LGPS LAG+ ++++LIP+N +S ++K YQ MK KD R++ M+E+L GIKV+KLYAWEPSF E++ IR SE++ L+K +YL A+ TFI+ FLVTL+T G YVY+D SNVLDAEKAFVS+S FN+++ PLN PQ I L QASVS KR+ +FLN E D + + + S +A+ + NG+F W + T+H +N++I +G+LVA+VG VG GKSSL+SA+LG+MEK G V+V G+VAYVPQQAWIQN T+++N+LFG+ P Y + + CAL+ D +L GDQTEIGEKGINLSGGQ+QRVSLARAVY++ +I+LLDDP+SAVD+HV KHIF+ VI GVL KTR+LVTH ++FL +TD I+V+ G++SEMG ++ L+ G F+ FL Y +Q+ + E+V +DTL ++L+ NE PA ++ + S+ +T K+ + T ++E G L+ EE ET V +VY YAK++GL T++I LY A ++G NVWL+ WS+D + + + + LG Y LG L VM+ + +G + A+ LH LL + +P SFFDT P GRILNRF KD+ +D + + F + TI+VI A+ PLF+VV +PL + Y F+Q+ Y+ TSRQLKRL SI+RSPI+S F ET++G I+A+ ++++KVD Q ++Y A+NRWL V +E +GN V+LFAALFAV+GR+ ++PG VGLS+SYA Q+T L ++IRM+S +E+N+++VER++EY EAP+V E WP RG + F++Y RYRPGL+LVLK +T + GEK+GIVGRTGAGKSS+T+ LFR++E + G I IDG ++ +GL LRS +TIIPQDP+LFSGT+R+NLDPF +++ IWRAL+L HL+ +VS GLD + +EGG NLSVGQRQLVCLARALLRK+++LVLDEATAA+DLE DDLIQ TIR +F+DCT+LTIAHRLNTIMD +RV+VL G++AE D P L+ IF+GMAK+AGL
Sbjct: 14 FWDSNLSIYTNTPDLTPCFQNSLLAWVPCIYLWAALPCYLFYLRHHQLGYIVLSWLSRLKT---ALGVLLWCVSWVDLFYSFHGLIHGSSPAPVFFVTPLVVGITMLLATLLIQYERLRGVQSSGVLIIFWLLCVICAIIPFRSKILSALAEGKILDPFRFTT----------FYIYFALVFCALILSCFKEKPPLF-SPENLDTNPCPEASAGFFSRLSFWWFTRLAILGYRRPLEDRDLWSLSEEDCSHKVVQRLLEAWQKQQNQASGSQTATAEPKIPGEDAVLLKPRPKSKQPSFLRALVRTFTSSLLMSACFNLIQNLLGFVN-------PQLLSILIRFISDPTAPTWWGFLLAGLMFLSSTMQTLILHQYYHCIFVMALRLRTAIIGVIYRKALVITNSVKRESTVGEMVNLMSVDAQRFMDVSPFINLLWSAPLQVILAIYFLWQILGPSALAGVAVIVLLIPLNGAVSMKMKTYQVKQMKFKDSRIKLMSEILNGIKVLKLYAWEPSFLEQVKGIRQSELQLLRKGAYLQAISTFIWICTPFLVTLITLGVYVYVDESNVLDAEKAFVSLSLFNILKIPLNMLPQLISGLTQASVSLKRIQDFLNQNELDPQCVERKTISPGYAITIHNGTFTWAQ-DLPPTLHSLNIQIPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGVVSVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVIGPE-GVLAGKTRVLVTHGISFLPQTDFIIVLAGGQVSEMGHYSALLQHDGSFANFLRNYAPDEDQEDHEAALQNANEEVLLLEDTLSTHTDLTDNE----------PAIYEVRKQFMREMSSLSSEGEVQNRTMPKKHTNSLEKEALVTKTKETGALIKEEIAETGNVKLSVYWDYAKSMGLCTTLSICLLYGGQSAAAIGANVWLSAWSNDAEEHGQQNKTSVRLGVYAALGILQGLLVMLSAFTMVVGAIQAARLLHEALLHNKIRSPQSFFDTTPSGRILNRFSKDIYVIDEVLAPTILMLLNSFFTSISTIMVIVASTPLFMVVVLPLAVLYGFVQRFYVATSRQLKRLESISRSPIFSHFSETVTGTSVIRAYGRIQDFKVLSDTKVDNNQKSSYPYIASNRWLGVHVEFVGNCVVLFAALFAVIGRNSLNPGLVGLSVSYALQVTMALNWMIRMISDLESNIIAVERVKEY-SKTKTEAPWVVESNRAPEG-WPTRGMVEFRNYSVRYRPGLELVLKNVTVHVQGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEIVIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGRYSEEDIWRALELSHLNTFVSSQPAGLDFQCAEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDLETDDLIQGTIRTQFEDCTVLTIAHRLNTIMDYNRVLVLDKGVVAEFDSPVNLIA-AGGIFYGMAKDAGL 1522
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. SwissProt
Match: gi|82231164|sp|Q5F364.1|MRP1_CHICK (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1232.24 bits (3187), Expect = 0.000e+0 Identity = 676/1578 (42.84%), Postives = 957/1578 (60.65%), Query Frame = 0
Query: 24 GLMKFCH----DPFWDLNTTWFTLDPDFTHCFHQTALVYVPCGLLWLLAPLEIYWINASQSRHIRWNLINVAKCISIALCIILDVISLSLSLGYFGNNTSWLSLSD--ILAPLIVFLTHALALILTLMNKKMGLTSSGILFTFWFVLVITSGLTFASVVRFG--------AFRTITSSWSVEQSMIYTIYFPLVVAISFLTFWADPPPVYWEVEDQVDVPSPEMYASFPSKIAFGWIDTLIKMGWQTPLNQRNIFDLN---------PNLTTNILTKKWAKHEKK----------------------------VRHPMRGTLKTDLIQTLARCFGVDFLIASGLQILGVLINQVFFVCCKAVPQTISLLITF-STSDEPLWRGYLYMSLLVAINMIRTLLNTQYFFIYLVLGQNVRTTLISAIYRKTFKLSASSRRQRSVGETVNLMSIDTERMNIVVGSLNNLWYAPLVILLSLYFLWGYLGPSCLAGLGMMIILIPINAWLSSRIKKYQFANMKKKDQRLETMNEVLEGIKVMKLYAWEPSFQEKIAAIRDSEVETLKKISYLGALQTFIFNSAVFLVTLVTFGTYVYLDPSNVLDAEKAFVSISYFNLMRGPLNQFPQFIIQLIQASVSHKRLDEFLNAPE--TDSKIIGNEPNSQHAVEVFNGSFAWDDTEDSSTIHGINLKIERGSLVAIVGQVGAGKSSLISAILGDMEKRTGSVNVDGTVAYVPQQAWIQNDTVRQNILFGRDHFPNIYFETVRACALVEDFTILEQGDQTEIGEKGINLSGGQKQRVSLARAVYNNRDIYLLDDPMSAVDAHVGKHIFEHVISSRTGVLKDKTRLLVTHNVTFLHETDLILVMKNGRISEMGTFNDLMSGGGDFSLFLAEYGNISEQDAGSVEQVETFQDTLDMVSNLSQNELNKTPPDPSSPAFLDLNSPLGSTI------GSVKIRKRNSAKTFRKRKGKVGPSSSNKT-----NSREKGKLVVEEKLETSAVSNAVYVYYAKAIGLFVTITIFGLYAVNQAFSVGTNVWLAKWSDDPQ-SAIPKYRDMYLGGYGGLGGASALTVMVVYLIITIGGLNASTKLHNNLLAKILAAPMSFFDTNPKGRILNRFGKDVDAVDTNVPSNFNSICRLLFNTFGTIVVICATNPLFIVVFIPLFLAYWFIQKLYITTSRQLKRLNSIARSPIYSLFGETLSGVPTIKAFNLQDQLIKINESKVDTLQTTTYLNQAANRWLSVRLEMLGNVVILFAALFAVLGRDKVDPGEVGLSLSYATQITTFLTFLIRMMSMIENNMVSVERIQEYEDHVDQEAPYVCPMESTLEKQWPPRGAIRFQDYKTRYRPGLDLVLKGITCDIHAGEKIGIVGRTGAGKSSLTMALFRLIEPSSGTIYIDGTDITTLGLGFLRSNITIIPQDPVLFSGTMRLNLDPFEIATDDQIWRALKLGHLSEYVSGLRYGLDQEISEGGGNLSVGQRQLVCLARALLRKTQILVLDEATAAVDLEMDDLIQTTIRQEFKDCTILTIAHRLNTIMDCDRVIVLRSGLIAEMDEPQKLLQDTNSIFFGMAKNAGL 1535
G+ C +PFWD N TW T +PDFT CF T LV+VPC LW+ P ++ + +I+ +++N AK AL +IL ++ + F + + + +++P ++ +T LA L + G+ SSG++ FW + ++ + + F S + AFR +T + YF L++ L+ + + PP++ E + P PE ASF S+I F WI L+ G + PL ++++ LN P L N K+WAK +++ + P + + + L + L + FG FL++ L + P+ + LLI F + P W+GY Y LL ++TL+ QYF I V G ++T ++ IYRK ++ S+R+ +VGE VNLMS+D +R + +N +W APL ++L+LY LW LGPS LAG+ +MI+L+PINA ++ + K YQ A MK KD R++ MNE+L GIKV+KLYAWE +F+EK+ IR E++ LKK +YL A+ TF + A FLV L TF YV ++ +N+LDA+KAFVS++ FN++R PLN P I +++ASVS KRL FL+ E DS I G N++ ++ V N +F+W T D +++ IN + GSL+A+VGQVG GKSSL+SA+LG+M+K+ G V V G++AYVPQQAWIQN T+ NI+FGR+ + Y + ACAL+ D IL GD+TEIGEKG+NLSGGQKQRVSLARAVY N D YL DDP+SAVDAHVGKHIFE VI + G+LK+KTR+LVTH V +L + D ILVM +G ISEMG++ +L+ G F+ FL Y N +EQ S D SSP+ + P+ + + G + R+ +++ T+ + GK SS + KL + +T V VY Y KAIGL+++ L+ N S+ +N WL+ W+DDP + +Y ++ LG YG LG + + V + ++IGG+ AS LH +LL +L +PMSFF+ P G +++RF K++D +D+ +P FN G ++I P+ VV PL L Y +Q+ Y+ TSRQLKRL S++RSP+YS F ETL GV I+AF Q + IK N+ KVD Q Y + ANRWL+VRLE +GN ++LFAALFAV+ R+K+ PG +GLS+SY+ QIT +L +L+RM S +E N+V+VER++EY + +++EA + E+ WP G + F+ + RYR LDLVLK I I+ GEK+GIVGRTGAGKSSLT+ LFR+ E + G I IDG +I +GL LR ITIIPQDP+LFSG++R+NLDPF+ +D+ IWR+L+L HL +VS L L+ E SEGG NLSVGQRQLVCLARALLRK++ILVLDEATAAVDLE D+LIQ+TI+ +F++CT+LTIAHRLNTIMD RV+VL G + E D P LLQ +F+ MAK++GL
Sbjct: 2 GIESLCSADASEPFWDWNLTWHTENPDFTQCFQNTVLVWVPCIYLWVCFPAYFLYLRSHDRGYIQMSILNKAKT---ALGLILWIVCWADLFYSFWERSQNIFRAPFFLISPTVLGITMLLATFLIQHERLKGVQSSGVMMIFWLISLLCATVIFRSKIMLALNTDTEVDAFRYVT----------FCTYFILLLVQLILSCFPEKPPLFSEAVNDPK-PCPEFSASFLSRITFWWITGLMIQGHRRPLEAKDLWSLNKEDTSEEIVPGLAKN-WAKEWAKTKRQPLNMLYSSKKQQKSSDSNGEVMEEAEALIIKPSQRSSEASLSKVLYKTFGPYFLMS-------FLFKAAHDLLMFTGPEILKLLINFVNNKSAPNWQGYFYTGLLFVCACLQTLILHQYFHICFVTGMRLKTAIVGVIYRKALVITNSARKTSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWRNLGPSVLAGVAVMILLVPINAVMAMKTKTYQVAQMKSKDNRIKLMNEILNGIKVLKLYAWELAFREKVLEIRQKELKVLKKSAYLAAMGTFTWVCAPFLVALSTFAVYVKVNKNNILDAQKAFVSLALFNILRFPLNILPMVISSIVEASVSLKRLRVFLSHEELDPDSIIRGPITNAEGSIVVKNATFSWSKT-DPPSLNSINFTVPEGSLIAVVGQVGCGKSSLLSALLGEMDKKEGYVVVKGSIAYVPQQAWIQNATLEDNIIFGREMNESRYKRVIEACALLPDLEILPMGDRTEIGEKGVNLSGGQKQRVSLARAVYCNADTYLFDDPLSAVDAHVGKHIFEKVIGPK-GILKNKTRVLVTHAVNYLPQMDTILVMTDGEISEMGSYQELLKQDGAFAEFLRTYAN-AEQSMES--------------------------SDASSPSGKE-GKPVENGVLVNDATGKLMHRQLSNSSTYSRETGKSQHQSSTAELQKPLAEKNSWKLTEADTAKTGRVKATVYWEYMKAIGLYISFLSVFLFMCNHIASLASNYWLSLWTDDPVVNGTQQYTNVRLGVYGALGISQGIAVFGYSMAVSIGGIFASRHLHLDLLHNVLRSPMSFFERTPSGNLVSRFSKEIDTIDSTIPPIIKMFMGSTFNVIGACIIILLATPIAAVVIPPLGLVYLLVQRFYVATSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQKRFIKQNDMKVDENQKAYYPSIVANRWLAVRLEFVGNCIVLFAALFAVIARNKLSPGLIGLSVSYSLQITAYLNWLVRMTSDLETNIVAVERVKEYAE-MEKEAEWSIE-ETAPASTWPQEGKVEFRGFGLRYREDLDLVLKNINITINGGEKVGIVGRTGAGKSSLTLGLFRINEAAEGEIIIDGINIAKIGLHDLRFKITIIPQDPILFSGSLRMNLDPFDQHSDEDIWRSLELAHLKNFVSSLPDKLNHECSEGGENLSVGQRQLVCLARALLRKSKILVLDEATAAVDLETDNLIQSTIKSQFEECTVLTIAHRLNTIMDYTRVLVLDRGEVVECDSPDNLLQ-AKGLFYSMAKDSGL 1524
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. SwissProt
Match: gi|75071939|sp|Q6UR05.1|MRP1_CANFA (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1228 bits (3176), Expect = 0.000e+0 Identity = 687/1575 (43.62%), Postives = 980/1575 (62.22%), Query Frame = 0
Query: 24 GLMKFCH----DPFWDLNTTWFTLDPDFTHCFHQTALVYVPCGLLWLLAPLEIYWINASQSRHIRWNLINVAKCISIALCIILDVISLSLSLGYFGNNTSW---LSLSDILAPLIVFLTHALALILTLMNKKMGLTSSGILFTFWFVLVITSGLTFASVVRFGAFRTITSSWSVE--QSMIYTIYFPLVVAISFLTFWADPPPVYWEVEDQVDVPSPEMYASFPSKIAFGWIDTLIKMGWQTPLNQRNIFDLNPNLTTN----ILTKKWAKHEKKVRHPMR-------------GTLKTD--------------------LIQTLARCFGVDFLIASGLQILGVLINQVFFVCCKAVPQTISLLITFSTSDE-PLWRGYLYMSLLVAINMIRTLLNTQYFFIYLVLGQNVRTTLISAIYRKTFKLSASSRRQRSVGETVNLMSIDTERMNIVVGSLNNLWYAPLVILLSLYFLWGYLGPSCLAGLGMMIILIPINAWLSSRIKKYQFANMKKKDQRLETMNEVLEGIKVMKLYAWEPSFQEKIAAIRDSEVETLKKISYLGALQTFIFNSAVFLVTLVTFGTYVYLDPSNVLDAEKAFVSISYFNLMRGPLNQFPQFIIQLIQASVSHKRLDEFLNAPETDSKIIGNEP----NSQHAVEVFNGSFAWDDTEDSSTIHGINLKIERGSLVAIVGQVGAGKSSLISAILGDMEKRTGSVNVDGTVAYVPQQAWIQNDTVRQNILFGRDHFPNIYFETVRACALVEDFTILEQGDQTEIGEKGINLSGGQKQRVSLARAVYNNRDIYLLDDPMSAVDAHVGKHIFEHVISSRTGVLKDKTRLLVTHNVTFLHETDLILVMKNGRISEMGTFNDLMSGGGDFSLFLAEYGN----ISEQDAGSV------EQVETFQDTLDMVSNLSQNELNKTPPDPSSPAFLDLNSPLGSTIGSVKIRKRNSAKTFRKRKGKVGPSSSNKTNSREKGKLVVEEKLETSAVSNAVYVYYAKAIGLFVTITIFGLYAVNQAFSVGTNVWLAKWSDDP-QSAIPKYRDMYLGGYGGLGGASALTVMVVYLIITIGGLNASTKLHNNLLAKILAAPMSFFDTNPKGRILNRFGKDVDAVDTNVPSNFNSICRLLFNTFGTIVVICATNPLFIVVFIPLFLAYWFIQKLYITTSRQLKRLNSIARSPIYSLFGETLSGVPTIKAFNLQDQLIKINESKVDTLQTTTYLNQAANRWLSVRLEMLGNVVILFAALFAVLGRDKVDPGEVGLSLSYATQITTFLTFLIRMMSMIENNMVSVERIQEYEDHVDQEAPYVCPMESTLEKQWPPRGAIRFQDYKTRYRPGLDLVLKGITCDIHAGEKIGIVGRTGAGKSSLTMALFRLIEPSSGTIYIDGTDITTLGLGFLRSNITIIPQDPVLFSGTMRLNLDPFEIATDDQIWRALKLGHLSEYVSGLRYGLDQEISEGGGNLSVGQRQLVCLARALLRKTQILVLDEATAAVDLEMDDLIQTTIRQEFKDCTILTIAHRLNTIMDCDRVIVLRSGLIAEMDEPQKLLQDTNSIFFGMAKNAGLM 1536
L FC DPFW+ + +W T +PDFT CF T LV+VPC LWL P +++ +I+ +N K AL +L ++ + L Y SW L+ +++P ++ +T LA L + ++ G+ SSGI+ TFW + ++ + +++R + ++ + + + IYF LV+ L+ ++D PP++ E ++ P PE ASF S++ F WI L+ G++ PL +++ LN T+ +L K W K K + R G + D L + L + FG FL++ + L L+ +F A P+ + LLI F + P W+GYLY +LL ++TL+ QYF I V G ++T +I A+YRK ++ S+R+ +VGE VNLMS+D +R + +N +W APL ++L+LY LW LGPS LAG+ +MI+++P+NA ++ + K YQ A+MK KD R++ MNE+L GIKV+KLYAWE +F++K+ AIR E++ LKK +YL A+ TF + FLV L TF YV +D +N+LDA+KAFVS++ FN++R PLN P I ++QASVS KRL FL+ E + I P +++ V N +F W + D T+ GI I GSLVA+VGQVG GKSSL+SA+L +M+K G V + G+VAYVPQQAWIQND++R+NILFGR Y + ACAL+ D IL GD+TEIGEKG+NLSGGQKQRVSLARAVY + DIYL DDP+SAVDAHVGKHIFE+VI + G+LK+KTRLLVTH++++L + D+I+VM G+ISEMG++ +L++ G F+ FL Y + +EQD G ++V+ ++ + +V++++ +L + + SS + G V ++A+ K GP + + KLV +K +T V +VY Y KAIGLF++ L+ N S+ +N WL+ W+DDP + ++ + L YG LG + +TV + ++IGG+ AS +LH +LL +L +PMSFF+ P G ++NRF K++D VD+ +P LFN G ++I P+ ++ PL L Y+F+Q+ Y+ +SRQLKRL S++RSP+YS F ETL GV I+AF Q++ I+ ++ KVD Q Y + ANRWL+VRLE +GN ++LFAALF+V+ R + G VGLS+SY+ Q+TT+L +L+RM S +E N+V+VER++EY + ++EAP+ E WP G + F+DY RYR LDLVLK I I+ GEK+GIVGRTGAGKSSLT+ LFR+ E + G I ID +I +GL LR ITIIPQDPVLFSG++R+NLDPF +D+++W +L+L HL ++VSGL L+QE +EGG NLSVGQRQLVCLARALLRKT+ILVLDEATAAVDLE DDLIQ+TIR +F DCT+LTIAHRLNTIMD RVIVL G I E +P LLQ +F+ MAK+AGL+
Sbjct: 2 ALRGFCSADGSDPFWEWDVSWNTSNPDFTKCFQNTVLVWVPCCYLWLCFPFYFLYLSRHDRGYIQMTYLNKTKT---ALGFVLWIVCWA-DLFYSFWERSWGKILAPVFLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLIALLCA----LAILRSKIMTALKEDAEIDVFRDVTFYIYFSLVLIQLVLSCFSDRPPLFSETIHDLN-PCPESSASFLSRVTFWWITGLMVRGYRQPLESTDLWSLNKEDTSEQVVPVLVKNWKKECAKSKRQQRKITYSSKDPAKPKGGSQVDVNEEAEVLIVKTPQKEREPSLFKVLYKTFGPYFLMSFLFKALHDLM--MF-----AGPEILKLLINFVNDKKAPDWQGYLYTALLFICACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMILMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDKNNILDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGANSITVKNATFTWARS-DPPTLSGITFSIPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGRQLQERYYKAVIEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCDSDIYLFDDPLSAVDAHVGKHIFENVIGPK-GMLKNKTRLLVTHSISYLPQVDVIIVMTGGKISEMGSYQELLARDGAFAEFLRTYASGDQEQAEQDDGLTGVSSPGKEVKQMENGM-LVTDVAGKQLQRQLSNSSSYS------------GDVSRHHTSTAEL-----QKAGP------KNEDAWKLVEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFLCNHVASLVSNYWLSLWTDDPIVNGTQEHTKIRLSVYGALGISQGITVFGYSMAVSIGGIFASRRLHVDLLQNVLRSPMSFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFNVIGACIIILLATPIASIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFSVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSE-TEKEAPWQI-QEMAPPSTWPQVGRVEFRDYGLRYRENLDLVLKHINITINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDDINIAKIGLHDLRVKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSGLPDKLNQECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFDDCTVLTIAHRLNTIMDYTRVIVLDKGEIRECGQPSDLLQQ-RGLFYSMAKDAGLV 1531
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. SwissProt
Match: gi|75072869|sp|Q864R9.1|MRP1_MACFA (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1222.99 bits (3163), Expect = 0.000e+0 Identity = 679/1574 (43.14%), Postives = 969/1574 (61.56%), Query Frame = 0
Query: 24 GLMKFCH----DPFWDLNTTWFTLDPDFTHCFHQTALVYVPCGLLWLLAPLEIYWINASQSRHIRWNLINVAKCISIALCIILDVISLSLSLGYFGNNTSWLSLSDI--LAPLIVFLTHALALILTLMNKKMGLTSSGILFTFWFVLVITSGLTFASVVRFGAFRTITSSWSVE--QSMIYTIYFPLVVAISFLTFWADPPPVYWEVEDQVDVPSPEMYASFPSKIAFGWIDTLIKMGWQTPLNQRNIFDLNPNLTTN----ILTKKWAKHEKKVR-HPMR------------GTLKTD--------------------LIQTLARCFGVDFLIASGLQILGVLINQVFFVCCKAVPQTISLLITF-STSDEPLWRGYLYMSLLVAINMIRTLLNTQYFFIYLVLGQNVRTTLISAIYRKTFKLSASSRRQRSVGETVNLMSIDTERMNIVVGSLNNLWYAPLVILLSLYFLWGYLGPSCLAGLGMMIILIPINAWLSSRIKKYQFANMKKKDQRLETMNEVLEGIKVMKLYAWEPSFQEKIAAIRDSEVETLKKISYLGALQTFIFNSAVFLVTLVTFGTYVYLDPSNVLDAEKAFVSISYFNLMRGPLNQFPQFIIQLIQASVSHKRLDEFLNAPETDSKIIGNEP----NSQHAVEVFNGSFAWDDTEDSSTIHGINLKIERGSLVAIVGQVGAGKSSLISAILGDMEKRTGSVNVDGTVAYVPQQAWIQNDTVRQNILFGRDHFPNIYFETVRACALVEDFTILEQGDQTEIGEKGINLSGGQKQRVSLARAVYNNRDIYLLDDPMSAVDAHVGKHIFEHVISSRTGVLKDKTRLLVTHNVTFLHETDLILVMKNGRISEMGTFNDLMSGGGDFSLFLAEYGNIS-EQD---------AGSVEQVETFQDTLDMVSNLSQNELNKTPPDPSSPAFLDLNSPLGSTIGSVKIRKRNSAKTFRKRKGKVGPSSSNKTNSREKGKLVVEEKLETSAVSNAVYVYYAKAIGLFVTITIFGLYAVNQAFSVGTNVWLAKWSDDP-QSAIPKYRDMYLGGYGGLGGASALTVMVVYLIITIGGLNASTKLHNNLLAKILAAPMSFFDTNPKGRILNRFGKDVDAVDTNVPSNFNSICRLLFNTFGTIVVICATNPLFIVVFIPLFLAYWFIQKLYITTSRQLKRLNSIARSPIYSLFGETLSGVPTIKAFNLQDQLIKINESKVDTLQTTTYLNQAANRWLSVRLEMLGNVVILFAALFAVLGRDKVDPGEVGLSLSYATQITTFLTFLIRMMSMIENNMVSVERIQEYEDHVDQEAPYVCPMESTLEKQWPPRGAIRFQDYKTRYRPGLDLVLKGITCDIHAGEKIGIVGRTGAGKSSLTMALFRLIEPSSGTIYIDGTDITTLGLGFLRSNITIIPQDPVLFSGTMRLNLDPFEIATDDQIWRALKLGHLSEYVSGLRYGLDQEISEGGGNLSVGQRQLVCLARALLRKTQILVLDEATAAVDLEMDDLIQTTIRQEFKDCTILTIAHRLNTIMDCDRVIVLRSGLIAEMDEPQKLLQDTNSIFFGMAKNAGLM 1536
L FC DP WD N TW+T +PDFT CF T LV+VPC LW P +++ +I+ L+N K AL +L ++ + F + + L+ + ++P ++ +T LA L + ++ G+ SSGI+ TFW V ++ + +++R + V+ + M + +YF LV+ L+ ++D P++ E + P PE ASF S+I F WI LI G++ PL +++ LN T+ +L K W K K R P++ + K D L + L + FG FL++ + + L+ +F + P+ + LLI F + + P W+GY Y +LL ++TL+ QYF I V G ++T +I A+YRK ++ ++R+ +VGE VNLMS+D +R + +N +W APL ++L+LY LW LGP LAG+ +M++++P+NA ++ + K YQ A+MK KD R++ MNE+L GIKV+KLYAWE +F++K+ AIR E++ LKK +YL A+ TF + FLV L TF YV +D +NVLDA+KAFVS++ FN++R PLN P I ++QASVS KRL FL+ E + I P +++ V N +F W + D T++GI I G+LVA+VGQVG GKSSL+SA+L +M+K G V + G+VAYVPQQAWIQND++++NILFG Y ++ACAL+ D IL GD+TEIGEKG+NLSGGQKQRVSLARAVY N DIYL DDP+SAVDAHVGKHIFE+VI + G+LK+KTR+LVTH++++L + D+I+VM G+ISEMG++ +L++ G F+ FL Y + EQD +G ++ + ++ + +V++ + +L + S S G V R+ NS +K K E KL+ +K +T V +VY Y KAIGLF++ L+ N ++ +N WL+ W+DDP + ++ + L YG LG + + V + ++IGG+ AS LH +LL IL +PMSFF+ P G ++NRF K++D VD+ +P LFN G +VI P+ ++ PL L Y+F+Q+ Y+ +SRQLKRL S++RSP+YS F ETL GV I+AF Q++ I ++ KVD Q Y + ANRWL+VRLE +GN ++LFAALFAV+ R + G VGLS+SY+ Q+TT+L +L+RM S +E N+V+VER++EY + ++EAP+ E+ WP G + F++Y RYR LD VL+ I I+ GEK+GIVGRTGAGKSSLT+ LFR+ E + G I IDG +I +GL LR ITIIPQDPVLFSG++R+NLDPF +D+++W +L+L HL +VS L LD E +EGG NLSVGQRQLVCLARALLRKT+ILVLDEATAAVDLE DDLIQ+TIR +F+DCT+LTIAHRLNTIMD RVIVL G I E P LLQ +F+ MA++AGL+
Sbjct: 2 ALRGFCSADGSDPLWDWNVTWYTSNPDFTKCFQNTVLVWVPCFYLWACFPFYFLYLSRHDRGYIQMTLLNKTKT---ALGFLLWIVCWADLFYSFWERSRGIFLAPVFLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALLCA----LAILRSKIMTALKEDVQVDLFRDMTFYVYFSLVLIQLVLSCFSDRSPLFSETIHDPN-PCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKDSSKVDANEEVEALIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLM--MF-----SGPEILKLLINFVNDTKAPDWQGYFYTALLFVAACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNAARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWRNLGPPILAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALCTFAVYVTIDKNNVLDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGDTNSITVRNATFTWARS-DPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVALKGSVAYVPQQAWIQNDSLQENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCNADIYLFDDPLSAVDAHVGKHIFENVIGPK-GMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASAEQEQDPEDNGVTGVSGPGKEAKQMENGM-LVTDSAGKQLQRQL------------SSSSSYSGDVS-RQHNSTAELQKDGAK----------KEETWKLMEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFICNHVAALASNYWLSLWTDDPIVNGTQEHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSE-TEKEAPWQI-QETAPPSNWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIARIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKGFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQ-RGLFYNMARDAGLV 1531 HSP 2 Score: 84.7297 bits (208), Expect = 6.239e-15 Identity = 104/468 (22.22%), Postives = 202/468 (43.16%), Query Frame = 0
Query: 1156 LFGETLSGVPTIKAFN----LQDQLIKINESKVDTLQTTTYLNQAAN-RWLSVRLEMLGNVVILFAALFAVLGRDKVDPGEVGLSLSYATQITTFLTFLIRMMSMIENNMVSVERIQEYEDHVDQEAPYVCPMESTLEKQWPPRGAIRFQDYKTRYRPGLDLVLKGITCDIHAGEKIGIVGRTGAGKSSLTMALFRLIEPSSGTIYIDGTDITTLGLGFLRSNITIIPQDPVLFSGTMRLNLDPFEIATDDQIWRA-LKLGHLSEYVSGLRYGLDQEISEGGGNLSVGQRQLVCLARALLRKTQILVLDEATAAVDLEMDDLIQTTI---RQEFKDCTILTIAHRLNTIMDCDRVIVLRSGLIAEMDEPQKLLQDTNSIFFGMAKNAGLMSEQEAKRQRVSDLLDAELDPKRISEIVGVSE----RTVRNIRAAKKIGNGVERKEGSGG----NGLKRNEAFLKSLEA 1606
L E L+G+ +K + +D+++ I + ++ L+ + YL W+ + + FA + + +D + +SL+ + L L ++S I VS++R++ + H + E + E K +I ++ + L GIT I G + +VG+ G GKSSL AL ++ G + + G+ + +PQ + + +++ N+ F ++ +R+ ++ L + L G EI E G NLS GQ+Q V LARA+ I + D+ +AVD + I + + K+ T + + H ++ + D +IV+ G I+EM Q+LL + + A EQ+ + V+ + + K++ + V++ + R + ++ V R+ S +G K+ E + K +EA
Sbjct: 504 LMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLAAVGTFTWVCTPFLV---ALCTFAVYVTIDKNNVLDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSI---ERRPVKDGGDTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVALKGS-------------VAYVPQQAWIQNDSLQENI-LFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASAEQEQDPEDNGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSSSSYSGDVSRQHNSTAELQKDGAKKEETW-KLMEA 950
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. SwissProt
Match: gi|52783101|sp|O35379.1|MRP1_MOUSE (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1221.07 bits (3158), Expect = 0.000e+0 Identity = 681/1574 (43.27%), Postives = 964/1574 (61.25%), Query Frame = 0
Query: 24 GLMKFCH----DPFWDLNTTWFTLDPDFTHCFHQTALVYVPCGLLWLLAPLEIYWINASQSRHIRWNLINVAKCISIALCIILDVISLSLSLGYFGNNTSWLSLSDIL--APLIVFLTHALALILTLMNKKMGLTSSGILFTFWFVLVITSGLTFASVVRFGAFRTITSSWSVE--QSMIYTIYFPLVVAISFLTFWADPPPVYWE-VEDQVDVPSPEMYASFPSKIAFGWIDTLIKMGWQTPLNQRNIFDLNPNLTTN----ILTKKWAKH-EKKVRHPMR-------------GTLKTD--------------------LIQTLARCFGVDFLIASGLQILGVLINQVFFVCCKAVPQTISLLITFSTSDE-PLWRGYLYMSLLVAINMIRTLLNTQYFFIYLVLGQNVRTTLISAIYRKTFKLSASSRRQRSVGETVNLMSIDTERMNIVVGSLNNLWYAPLVILLSLYFLWGYLGPSCLAGLGMMIILIPINAWLSSRIKKYQFANMKKKDQRLETMNEVLEGIKVMKLYAWEPSFQEKIAAIRDSEVETLKKISYLGALQTFIFNSAVFLVTLVTFGTYVYLDPSNVLDAEKAFVSISYFNLMRGPLNQFPQFIIQLIQASVSHKRLDEFLNAPETDSKIIGN---EPNSQHAVEVFNGSFAWDDTEDSSTIHGINLKIERGSLVAIVGQVGAGKSSLISAILGDMEKRTGSVNVDGTVAYVPQQAWIQNDTVRQNILFGRDHFPNIYFETVRACALVEDFTILEQGDQTEIGEKGINLSGGQKQRVSLARAVYNNRDIYLLDDPMSAVDAHVGKHIFEHVISSRTGVLKDKTRLLVTHNVTFLHETDLILVMKNGRISEMGTFNDLMSGGGDFSLFLAEYGNISEQD--------AGSVEQVETFQDTLDMVSNLSQNELNKTPPDPSSPAFLDLNSPLGSTIGSVKIRKRNSAKTFRKRKGKVGPSSSNKTNSREKGKLVVEEKLETSAVSNAVYVYYAKAIGLFVTITIFGLYAVNQAFSVGTNVWLAKWSDDPQ--SAIPKYRDMYLGGYGGLGGASALTVMVVYLIITIGGLNASTKLHNNLLAKILAAPMSFFDTNPKGRILNRFGKDVDAVDTNVPSNFNSICRLLFNTFGTIVVICATNPLFIVVFIPLFLAYWFIQKLYITTSRQLKRLNSIARSPIYSLFGETLSGVPTIKAFNLQDQLIKINESKVDTLQTTTYLNQAANRWLSVRLEMLGNVVILFAALFAVLGRDKVDPGEVGLSLSYATQITTFLTFLIRMMSMIENNMVSVERIQEYEDHVDQEAPYVCPMESTLEKQWPPRGAIRFQDYKTRYRPGLDLVLKGITCDIHAGEKIGIVGRTGAGKSSLTMALFRLIEPSSGTIYIDGTDITTLGLGFLRSNITIIPQDPVLFSGTMRLNLDPFEIATDDQIWRALKLGHLSEYVSGLRYGLDQEISEGGGNLSVGQRQLVCLARALLRKTQILVLDEATAAVDLEMDDLIQTTIRQEFKDCTILTIAHRLNTIMDCDRVIVLRSGLIAEMDEPQKLLQDTNSIFFGMAKNAGLM 1536
L FC DP WD N TW T +PDFT CF T L +VPC LW PL ++++ +I+ +N K AL L +I + F + + + +L +P ++ +T LA L + ++ G+ SSGI+ TFW V ++ + +++R + V+ + + +YF LV+ L+ ++D P++ E V D+ P PE ASF S+I F WI ++ G++ PL +++ LN T+ +L W K +K + P+R G+ + D L + L + FG FL++ + L L+ +F A P+ + L+I F E P W+GY Y +LL ++TL QYF I V G ++T ++ A+YRK ++ ++R+ +VGE VNLMS+D +R + +N +W APL ++L+LYFLW LGPS LAG+ +MI+++P+NA ++ + K YQ A+MK KD R++ MNE+L GIKV+KLYAWE +FQ+K+ +IR E++ LKK +YL A+ TF + FLV L TF +V +D N+LDA+KAFVS++ FN++R PLN P I ++QASVS KRL FL+ E + I + +++ V N +F W E T++GI I G+LVA+VGQVG GKSSL+SA+L +M+K G V + G+VAYVPQQAWIQND++R+NILFG N Y + ACAL+ D IL GD+TEIGEKG+NLSGGQKQRVSLARAVY+N DIYL DDP+SAVDAHVGKHIFE V+ G+LK+KTR+LVTH +++L + D+I+VM G+ISEMG++ +L+ G F+ FL Y N +EQD +GS ++ + ++ + +V++ L + + SS + G T ++ +S +K K E KL+ +K +T V +VY Y KAIGLF+T L+ N ++ +N WL+ W+DDP + R+ L YG LG + + ++IGG+ AS +LH +LL +L +PMSFF+ P G ++NRF K++D VD+ +P LF+ G +++I P+ V+ PL L Y+F+Q+ Y+ +SRQLKRL S++RSP+YS F ETL GV I+AF Q++ I ++ KVD Q Y + ANRWL+VRLE +GN ++LFAALFAV+ R + G VGLS+SY+ QIT +L +L+RM S +E N+V+VER++EY + ++EAP+ E+ WP G + F+DY RYR LDLVLK I I GEK+GIVGRTGAGKSSLT+ LFR+ E + G I IDG +I +GL LR ITIIPQDPVLFSG++R+NLDPF +D+++W AL+L HL +VS L L+ E +EGG NLSVGQRQLVCLARALLRKT+ILVLDEATAAVDLE D+LIQ+TIR +F+DCT+LTIAHRLNTIMD RVIVL G + E P +LLQ IF+ MAK+AGL+
Sbjct: 2 ALRSFCSADGSDPLWDWNVTWHTSNPDFTKCFQNTVLTWVPCFYLWSCFPLYFFYLSRHDRGYIQMTHLNKTKT---ALGFFLWIICWADLFYSFWERSQGVLRAPVLLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALLCA----LAILRSKIISALKKDAHVDVFRDSTFYLYFTLVLVQLVLSCFSDCSPLFSETVHDRN--PCPESSASFLSRITFWWITGMMVHGYRQPLESSDLWSLNKEDTSEEVVPVLVNNWKKECDKSRKQPVRIVYAPPKDPSKPKGSSQLDVNEEVEALIVKSPHKDREPSLFKVLYKTFGPYFLMSFLYKALHDLM--MF-----AGPKILELIINFVNDREAPDWQGYFYTALLFVSACLQTLALHQYFHICFVSGMRIKTAVVGAVYRKALLITNAARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYFLWLSLGPSVLAGVAVMILMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFQDKVMSIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVFVTVDERNILDAKKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRSIKSGEGNSITVKNATFTWARGE-PPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVTLKGSVAYVPQQAWIQNDSLRENILFGHPLQENYYKAVMEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNSDIYLFDDPLSAVDAHVGKHIFEKVVGP-MGLLKNKTRILVTHGISYLPQVDVIIVMSGGKISEMGSYQELLDRDGAFAEFLRTYAN-AEQDLASEDDSVSGSGKESKPVENGM-LVTDTVGKHLQRHLSNSSSHS--------GDTS-----QQHSSIAELQKAGAK-----------EETWKLMEADKAQTGQVQLSVYWNYMKAIGLFITFLSIFLFLCNHVSALASNYWLSLWTDDPPVVNGTQANRNFRLSVYGALGILQGAAIFGYSMAVSIGGIFASRRLHLDLLYNVLRSPMSFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFSVIGAVIIILLATPIAAVIIPPLGLVYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQITAYLNWLVRMSSEMETNIVAVERLKEYSE-TEKEAPWQI-QETAPPSTWPHSGRVEFRDYCLRYREDLDLVLKHINVTIEGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGVNIAKIGLHNLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWMALELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEVRECGAPSELLQQ-RGIFYSMAKDAGLV 1528
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. SwissProt
Match: gi|6016599|sp|O88563.1|MRP3_RAT (RecName: Full=Canalicular multispecific organic anion transporter 2; AltName: Full=ATP-binding cassette sub-family C member 3; AltName: Full=MRP-like protein 2; Short=MLP-2; AltName: Full=Multidrug resistance-associated protein 3) HSP 1 Score: 1216.45 bits (3146), Expect = 0.000e+0 Identity = 665/1548 (42.96%), Postives = 952/1548 (61.50%), Query Frame = 0
Query: 33 FWDLNTTWFTLDPDFTHCFHQTALVYVPCGLLWLLAPLEIYWINASQSRHIRWNLINVAKCIS---IALCIILDVIS-LSLSLGYFG-NNTSWLSLSDILAPLIVFLTHALALILTLMNKKMGLTSSGILFTFWFVLVITSGLTFASVVRFG--------AFRTITSSWSVEQSMIYTIYFPLVVAISFLTFWADPPPVYWEVEDQVDVPSPEMYASFPSKIAFGWIDTLIKMGWQTPLNQRNIFDLNPNLTTNILTKK----WAKHEKKVRHPMRGTL-------------------KTDLIQTLARCFGVDFLIASGLQILGVLINQVFFVCCKAVPQTISLLITFSTSDEPLWRGYLYMSLLVAINMIRTLLNTQYFFIYLVLGQNVRTTLISAIYRKTFKLSASSRRQRSVGETVNLMSIDTERMNIVVGSLNNLWYAPLVILLSLYFLWGYLGPSCLAGLGMMIILIPINAWLSSRIKKYQFANMKKKDQRLETMNEVLEGIKVMKLYAWEPSFQEKIAAIRDSEVETLKKISYLGALQTFIFNSAVFLVTLVTFGTYVYLDPSNVLDAEKAFVSISYFNLMRGPLNQFPQFIIQLIQASVSHKRLDEFLNAPETDSKIIGNEPNSQ-HAVEVFNGSFAWDDTEDSSTIHGINLKIERGSLVAIVGQVGAGKSSLISAILGDMEKRTGSVNVDGTVAYVPQQAWIQNDTVRQNILFGRDHFPNIYFETVRACALVEDFTILEQGDQTEIGEKGINLSGGQKQRVSLARAVYNNRDIYLLDDPMSAVDAHVGKHIFEHVISSRTGVLKDKTRLLVTHNVTFLHETDLILVMKNGRISEMGTFNDLMSGGGDFSLFLAEYGNISEQDAG------SVEQVETFQDTLDMVSNLSQNELNKTPPDPSSPAFLDLNSPLGSTIGSVKIRKRNSAKTFRKRKGKVGPSSSNKTNSREKGKLVVEEKLETSAVSNAVYVYYAKAIGLFVTITIFGLYAVNQAFSVGTNVWLAKWSDD-PQSAIPKYRDMYLGGYGGLGGASALTVMVVYLIITIGGLNASTKLHNNLLAKILAAPMSFFDTNPKGRILNRFGKDVDAVDTNVPSNFNSICRLLFNTFGTIVVICATNPLFIVVFIPLFLAYWFIQKLYITTSRQLKRLNSIARSPIYSLFGETLSGVPTIKAFNLQDQLIKINESKVDTLQTTTYLNQAANRWLSVRLEMLGNVVILFAALFAVLGRDKVDPGEVGLSLSYATQITTFLTFLIRMMSMIENNMVSVERIQEYEDHVDQEAPYVCPMESTLEKQ-WPPRGAIRFQDYKTRYRPGLDLVLKGITCDIHAGEKIGIVGRTGAGKSSLTMALFRLIEPSSGTIYIDGTDITTLGLGFLRSNITIIPQDPVLFSGTMRLNLDPFEIATDDQIWRALKLGHLSEYVSGLRYGLDQEISEGGGNLSVGQRQLVCLARALLRKTQILVLDEATAAVDLEMDDLIQTTIRQEFKDCTILTIAHRLNTIMDCDRVIVLRSGLIAEMDEPQKLLQDTNSIFFGMAKNAGL 1535
FWD N T +T PD T CF + L +VPC LW P ++++ RH R I V C+S AL ++L IS + L + G + S + + PL+V +T LA +L + G+ SSG+L FW + VI + + F S + FR T + IYF LV+ L+ + + PP++ E+ P PE A F S+++F W L +G++ PL +++ L+ ++ + ++ W K + + P L K ++ L R F L+ + +++ L + + P W G+L L+ + ++TL+ Q++ V+ +RT +I IYRK ++ S +R+ +VGE VNLMS+D +R V +N LW APL ++L++YFLW LGPS LAG+ ++++LIP+N +S ++K YQ MK KD R++ M+E+L GIKV+KLYAWEP+F E++ IR E++ L+K +YL A+ TFI+ F+VTL+T G YV +D +NVLDAEKAFVS+S FN+++ PLN PQ I + Q SVS KR+ +FLN E D + + + S A+ + NG+F+W + T+H IN++I +G+LVA+VG VG GKSSL+SA+LG+MEK G+V+V G+VAYVPQQAWIQN T+++N+LFG+ P Y + + CAL+ D +L GDQTEIGEKGINLSGGQ+QRVSLARAVY++ +I+LLDDP+SAVD+HV KHIF+ VI GVL KTR+LVTH ++FL +TD I+V+ +G+I+EMG +++L+ G F+ FL Y Q+A + E+V +DTL ++L+ E PA ++ + S+ + KR T ++E G L+ EE ET V +VY YAK++GL T+ I LYA A ++G NVWL+ W++D + + LG Y LG L VM+ + +G + A+ LH LL + AP SFFDT P GRILNRF KD+ + + + + + TIVVI A+ PLF VV +PL + Y F+Q+ Y+ TSRQLKRL S++RSPI+S F ET++G I+A+ ++++KVD+ Q TTY A+NRWL V +E +GN V+LF+ALFAV+GR+ ++PG VGLS+SYA Q+T L ++IR +S +E+N+++VER++EY + EAP+V +ES + WP G + F++Y RYRPGL+LVLK +T + GEK+GIVGRTGAGKSS+T+ LFR++E + G I+IDG ++ +GL LRS +TIIPQDP+LFSGT+R+NLDPF +D+ IWR L+L HLS +VS GLD + SEGG NLSVGQRQLVCLARALLRK+++LVLDEATAA+DLE DDLIQ TIR +F+DCT+LTIAHRLNTIMD +RV+VL G++AE D P L+ IF+GMAK+AGL
Sbjct: 14 FWDSNLTVYTNTPDLTPCFQNSLLAWVPCIYLWAALPCYLFYL-----RHHRLGYI-VLSCLSRLKTALGVLLWCISWVDLFYSFHGLVHGSSPAPVFFITPLLVGITMLLATLLIQYERLRGVRSSGVLIIFWLLCVICAIIPFRSKILLALAEGKILDPFRFTT----------FYIYFALVLCAFILSCFQEKPPLF-SPENLDTNPCPEASAGFFSRLSFWWFTKLAILGYRRPLEDSDLWSLSEEDCSHKVVQRLLEAWQKQQTQASGPQTAALEPKIAGEDEVLLKARPKTKKPSFLRALVRTFTSSLLMGACFKLIQDL-------SPSSTHSCSASSSGLFRPHGPYWWGFLLAGLMFVSSTMQTLILHQHYHCIFVMALRIRTAIIGVIYRKALTITNSVKREYTVGEMVNLMSVDAQRFMDVSPFINLLWSAPLQVILAIYFLWQILGPSALAGVAVIVLLIPLNGAVSMKMKTYQVQQMKFKDSRIKLMSEILNGIKVLKLYAWEPTFLEQVEGIRQGELQLLRKGAYLQAISTFIWVCTPFMVTLITLGVYVCVDKNNVLDAEKAFVSLSLFNILKIPLNLLPQLISGMTQTSVSLKRIQDFLNQDELDPQCVERKTISPGRAITIHNGTFSWSK-DLPPTLHSINIQIPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGAVSVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVIGPE-GVLAGKTRVLVTHGISFLPQTDFIIVLADGQITEMGHYSELLQHDGSFANFLRNYAPDENQEANEGVLQHANEEVLLLEDTLSTHTDLTDTE----------PAIYEVRKQFMREMSSLSSEGEGQNRPVLKRYTSSLEKEVPATQTKETGALIKEEIAETGNVKLSVYWDYAKSVGLCTTLFICLLYAGQNAVAIGANVWLSAWTNDVEEHGQQNNTSVRLGVYATLGILQGLLVMLSAFTMVVGAIQAARLLHTALLHNQIRAPQSFFDTTPSGRILNRFSKDIYVIHEVLAPTILMLFNSFYTSISTIVVIVASTPLFCVVVLPLAVFYGFVQRFYVATSRQLKRLESVSRSPIFSHFSETVTGTSVIRAYGRVQDFKVLSDAKVDSNQKTTYPYIASNRWLGVHVEFVGNCVVLFSALFAVIGRNSLNPGLVGLSVSYALQVTLSLNWMIRTLSDLESNIIAVERVKEYSK-TETEAPWV--LESNRAPEGWPRSGVVEFRNYSVRYRPGLELVLKNLTLHVQGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEIFIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGRYSDEDIWRTLELSHLSAFVSSQPTGLDFQCSEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDLETDDLIQGTIRTQFEDCTVLTIAHRLNTIMDYNRVLVLDKGVVAEFDSPVNLIA-AGGIFYGMAKDAGL 1521
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. SwissProt
Match: gi|85701143|sp|Q8CG09.2|MRP1_RAT (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1213.36 bits (3138), Expect = 0.000e+0 Identity = 684/1572 (43.51%), Postives = 958/1572 (60.94%), Query Frame = 0
Query: 24 GLMKFCH----DPFWDLNTTWFTLDPDFTHCFHQTALVYVPCGLLWLLAPLEIYWINASQSRHIRWNLINVAKCISIALCIILDVISLSLSLGYFGNNTSWLSLSDIL--APLIVFLTHALALILTLMNKKMGLTSSGILFTFWFVLVITSGLTFASVVRFGAFRTITSSWSVE--QSMIYTIYFPLVVAISFLTFWADPPPVYWEVEDQVDVPSPEMYASFPSKIAFGWIDTLIKMGWQTPLNQRNIFDLNPNLTTN----ILTKKWAKHEKKVR-HPMR-------------GTLKTD--------------------LIQTLARCFGVDFLIASGLQILGVLINQVFFVCCKAVPQTISLLITFSTSDE-PLWRGYLYMSLLVAINMIRTLLNTQYFFIYLVLGQNVRTTLISAIYRKTFKLSASSRRQRSVGETVNLMSIDTERMNIVVGSLNNLWYAPLVILLSLYFLWGYLGPSCLAGLGMMIILIPINAWLSSRIKKYQFANMKKKDQRLETMNEVLEGIKVMKLYAWEPSFQEKIAAIRDSEVETLKKISYLGALQTFIFNSAVFLVTLVTFGTYVYLDPSNVLDAEKAFVSISYFNLMRGPLNQFPQFIIQLIQASVSHKRLDEFLNAPETDSKIIG----NEPNSQHAVEVFNGSFAWDDTEDSSTIHGINLKIERGSLVAIVGQVGAGKSSLISAILGDMEKRTGSVNVDGTVAYVPQQAWIQNDTVRQNILFGRDHFPNIYFETVRACALVEDFTILEQGDQTEIGEKGINLSGGQKQRVSLARAVYNNRDIYLLDDPMSAVDAHVGKHIFEHVISSRTGVLKDKTRLLVTHNVTFLHETDLILVMKNGRISEMGTFNDLMSGGGDFSLFLAEYGNISEQDAGSVEQVETFQDTLDMVSNLSQNELNKTPPDPSSPAFLD-LNSPL-----GSTIGSVKIRKRNSAKTFRKRKGKVGPSSSNKTNSREKGKLVVEEKLETSAVSNAVYVYYAKAIGLFVTITIFGLYAVNQAFSVGTNVWLAKWSDDPQS--AIPKYRDMYLGGYGGLGGASALTVMVVYLIITIGGLNASTKLHNNLLAKILAAPMSFFDTNPKGRILNRFGKDVDAVDTNVPSNFNSICRLLFNTFGTIVVICATNPLFIVVFIPLFLAYWFIQKLYITTSRQLKRLNSIARSPIYSLFGETLSGVPTIKAFNLQDQLIKINESKVDTLQTTTYLNQAANRWLSVRLEMLGNVVILFAALFAVLGRDKVDPGEVGLSLSYATQITTFLTFLIRMMSMIENNMVSVERIQEYEDHVDQEAPYVCPMESTLEKQWPPRGAIRFQDYKTRYRPGLDLVLKGITCDIHAGEKIGIVGRTGAGKSSLTMALFRLIEPSSGTIYIDGTDITTLGLGFLRSNITIIPQDPVLFSGTMRLNLDPFEIATDDQIWRALKLGHLSEYVSGLRYGLDQEISEGGGNLSVGQRQLVCLARALLRKTQILVLDEATAAVDLEMDDLIQTTIRQEFKDCTILTIAHRLNTIMDCDRVIVLRSGLIAEMDEPQKLLQDTNSIFFGMAKNAGLM 1536
L FC DP WD N TW T +PDFT CF T L +VPC LW PL +++ +I+ +N AK AL L +I + F + + L+ +L +P ++ +T LA L ++ G+ SSGI+ TFW V ++ + +++R + V+ + + +YF LV L+ ++D P++ E + P PE ASF S+I F WI ++ G++ PL +++ LN T+ +L W K K R P+R G+ + D L + L + FG FL++ + L L+ +F A P+ + L+I F E P W+GYLY +LL ++TL QYF I V G ++T ++ A+YRK ++ S+R+ +VGE VNLMS+D +R + +N +W APL + L+LYFLW LGPS LAG+ +MI+++P NA ++ + K YQ A+MK KD R++ MNE+L GIKV+KLYAWE +FQ+K+ IR E++ LKK +YL A+ TF + FLV L TF +V +D N+LDA+KAFVS++ FN++R PLN P I ++QASVS KRL FL+ E + I + +++ V N +F W E T++GI I G+LVA+VGQVG GKSSL+SA+L +M+K G V + G+VAYVPQQAWIQND++R+NILFGR + Y + ACAL+ D IL GD TEIGEKG+NLSGGQKQRVSLARAVY N DIYLLDDP+SAVDAHVGKHIFE V+ G+LK+KTR+LVTH +++L + D+I+VM G+ISEMG++ +L+ G F+ F+ Y N +EQD S + D+ + VS L + ++ P + D + PL S+ SV +++S+ ++ G E KL+ +K +T V +VY Y KAIGL ++ L+ N ++ +N WL+ W+DD + + R+ L YG LG + V + ++IGG+ AS +LH +LL +L +PMSFF+ P G ++NRF K++D VD+ +P LF+ G +++I P+ V+ PL L Y+F+Q+ Y+ +SRQLKRL S++RSP+YS F ETL GV I+AF Q++ I+ ++ KVD Q Y + ANRWL+VRLE +GN ++LFAALFAV+ R + G VGLS+SY+ QIT +L +L+RM S +E N+V+VER++EY + ++EA + E+ WP G + F+DY RYR LDLVLK I I GEK+GIVGRTGAGKSSLT+ LFR+ E + G I IDG +I +GL LR ITIIPQDPVLFSG++R+NLDPF +D+++W AL+L HL +VS L L+ E +EGG NLSVGQRQLVCLARALLRKT+ILVLDEATAAVDLE DDLIQ+TIR +F+D T+LTIAHRLNTIMD RVIVL G I E P +LLQ +F+ MAK+AGL+
Sbjct: 2 ALSSFCSSDGSDPLWDWNVTWHTSNPDFTKCFQNTVLTWVPCFYLWSCFPLYFLYLSRHDRGYIQMTHLNKAKT---ALGFFLWIICWADLFYSFWERSQGMLLAPVLLVSPTLLGITMLLATFLIQFERRKGVQSSGIMLTFWLVALLCA----LAILRSKIISALKKDAQVDMFRDSAFYLYFTLVFIQLVLSCFSDSSPLFSETVRDPN-PCPESSASFLSRITFWWITGMMVQGYRQPLKSSDLWSLNKEDTSEEVVPVLVNNWKKECVKSRKQPVRIVYAPPKDPTKPKGSSQLDVNEEVEALIVKSSHKDRDPSLFKVLYKTFGPYFLMSFLYKALHDLM--MF-----AGPEILELIINFVNDREAPDWQGYLYTALLFVSACLQTLALHQYFHICFVTGMRIKTAVVGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVTLALYFLWLNLGPSVLAGVAVMILMVPFNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFQDKVMNIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVFVTVDEKNILDAKKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERWSIKDGGGMNSITVKNATFTWARDE-PPTLNGITFAIPDGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVTLKGSVAYVPQQAWIQNDSLRENILFGRPLQEHCYKAVMEACALLPDLEILPSGDLTEIGEKGVNLSGGQKQRVSLARAVYCNSDIYLLDDPLSAVDAHVGKHIFEKVVGP-MGLLKNKTRILVTHGISYLPQVDVIIVMSGGKISEMGSYQELLDRDGAFAEFVRTYAN-TEQDLASED------DSKNGVSGLGK----ESKPVENGILVTDAVGKPLQRHLSNSSSHSVVTNQQHSSTAELQKSGV----------KEETWKLMEADKAQTGQVKLSVYWNYMKAIGLCISFLSIFLFLCNHVSALASNYWLSLWTDDRPAVNGTQENRNFRLSVYGALGILQGVAVFGYSMAVSIGGIFASRRLHLDLLQNVLRSPMSFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFSVIGAVIIILLATPIAAVIIPPLGLVYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQITAYLNWLVRMSSEMETNIVAVERLKEYSE-TEKEASWQI-QETAPPSTWPHSGRVEFRDYCLRYREDLDLVLKHINVTIEGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHNLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWMALELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDSTVLTIAHRLNTIMDYTRVIVLDKGEIRECGAPSELLQQ-RGVFYSMAKDAGLV 1532
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. SwissProt
Match: gi|75072999|sp|Q8HXQ5.1|MRP1_BOVIN (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1212.21 bits (3135), Expect = 0.000e+0 Identity = 687/1574 (43.65%), Postives = 962/1574 (61.12%), Query Frame = 0
Query: 24 GLMKFCH----DPFWDLNTTWFTLDPDFTHCFHQTALVYVPCGLLWLLAPLEIYWINASQSRHIRWNLINVAKCISIALCIILDVISLSLSLGYFGNNTSWLSLSDI--LAPLIVFLTHALALILTLMNKKMGLTSSGILFTFWFVLVITSGLTFASVV--------RFGAFRTITSSWSVEQSMIYTIYFPLVVAISFLTFWADPPPVYWEVEDQVDVPSPEMYASFPSKIAFGWIDTLIKMGWQTPLNQRNIFDLNPNLTTN----ILTKKWAKHEKKVR-HPMR------------GTLKTD--------------------LIQTLARCFGVDFLIASGLQILGVLINQVFFVCCKAVPQTISLLITFSTSDE-PLWRGYLYMSLLVAINMIRTLLNTQYFFIYLVLGQNVRTTLISAIYRKTFKLSASSRRQRSVGETVNLMSIDTERMNIVVGSLNNLWYAPLVILLSLYFLWGYLGPSCLAGLGMMIILIPINAWLSSRIKKYQFANMKKKDQRLETMNEVLEGIKVMKLYAWEPSFQEKIAAIRDSEVETLKKISYLGALQTFIFNSAVFLVTLVTFGTYVYLDPSNVLDAEKAFVSISYFNLMRGPLNQFPQFIIQLIQASVSHKRLDEFLNAPETDSKIIGNEP----NSQHAVEVFNGSFAWDDTEDSSTIHGINLKIERGSLVAIVGQVGAGKSSLISAILGDMEKRTGSVNVDGTVAYVPQQAWIQNDTVRQNILFGRDHFPNIYFETVRACALVEDFTILEQGDQTEIGEKGINLSGGQKQRVSLARAVYNNRDIYLLDDPMSAVDAHVGKHIFEHVISSRTGVLKDKTRLLVTHNVTFLHETDLILVMKNGRISEMGTFNDLMSGGGDFSLFLAEYGNISEQDAGSVEQVETFQDTLDMV----SNLSQNELNKTPPDPSSPAFLDLNSPLGSTIGSVKIRKRNSAKTFRKRKGKVGPSSSNKTNSREKGKLVVEEKLETSAVSNAVYVYYAKAIGLFVTITIFGLYAVNQAFSVGTNVWLAKWSDDP-QSAIPKYRDMYLGGYGGLGGASALTVMVVYLIITIGGLNASTKLHNNLLAKILAAPMSFFDTNPKGRILNRFGKDVDAVDTNVPSNFNSICRLLFNTFGTIVVICATNPLFIVVFIPLFLAYWFIQKLYITTSRQLKRLNSIARSPIYSLFGETLSGVPTIKAFNLQDQLIKINESKVDTLQTTTYLNQAANRWLSVRLEMLGNVVILFAALFAVLGRDKVDPGEVGLSLSYATQITTFLTFLIRMMSMIENNMVSVERIQEYEDHVDQEAPYVCPMESTLEKQWPPRGAIRFQDYKTRYRPGLDLVLKGITCDIHAGEKIGIVGRTGAGKSSLTMALFRLIEPSSGTIYIDGTDITTLGLGFLRSNITIIPQDPVLFSGTMRLNLDPFEIATDDQIWRALKLGHLSEYVSGLRYGLDQEISEGGGNLSVGQRQLVCLARALLRKTQILVLDEATAAVDLEMDDLIQTTIRQEFKDCTILTIAHRLNTIMDCDRVIVLRSGLIAEMDEPQKLLQDTNSIFFGMAKNAGLM 1536
L FC D FW+ N TW T +PDFT CF T LV+VPC LW+ P +++ +I+ +N AK AL +L ++ + F + L+ + ++P ++ +T LA L + ++ G+ SSGI+ TFW + ++ + S + R FR +T + IYF LV+ L+ ++D P++ E + + P PE ASF S+I F WI ++ G++ PL +++ LN T+ +L K W K K R P++ G+ K D L + L + FG FL++ L V + A P+ + LLI F + P W+GY Y +LL ++TL+ QYF I V G ++T +I A+YRK ++ ++R+ +VGE VNLMS+D +R + +N +W APL ++L+LY LW LGPS LAG+ +M++++P+NA ++ + K YQ A+MK KD R++ MNE+L GIKV+KLYAWE +F++K+ AIR E++ LKK +YL A+ TF + FLV L TF YV +D +N+LDA+KAFVS++ FN++R PLN P I ++QASVS KRL FL+ + D I P + +++ V N +F W D T+HGI + GSLVA+VGQVG GKSSL+SA+L +M+K G V V G+VAYVPQQAWIQN ++R+NILFGR Y V ACAL+ D IL GD+TEIGEKG+NLSGGQKQRVSLARAVY + D+YLLDDP+SAVDAHVGKHIFE+VI + G+LK+KTRLLVTH +++L + D+I+VM G+ISEMG++ +L++ G F+ FL Y + +EQ+ G E D L V + Q E D + + L S+ + ++ T RK GP+ E KLV +K +T V +VY Y KAIGLF++ L+ N S+ +N WL+ W+DDP + ++ + L YG LG + +TV + ++IGG+ AS +LH +LL +L +P+SFF+ P G ++NRF K++D VD+ +P LFN G ++I P+ V+ PL L Y+F+Q+ Y+ +SRQLKRL S++RSP+YS F ETL GV I+AF Q++ I+ ++ KVD Q Y + ANRWL+VRLE +GN ++LFA+LFAV+ R + G VGLS+SY+ Q+TT+L +L+RM S +E N+V+VER++EY + ++EAP+ + K WP G + F+DY RYR LDLVLK I I GEK+GIVGRTGAGKSSLT+ LFR+ E + G I ID +I +GL LR ITIIPQDPVLFSG++R+NLDPF +D+++W +L+L HL +VS L L+ E +EGG NLSVGQRQLVCLARALLRKT+ILVLDEATAAVDLE DDLIQ+TIR +F DCT+LTIAHRLNTIMD RVIVL G I E P LLQ +F+ MAK++GL+
Sbjct: 2 ALRDFCSVDGSDLFWEWNVTWNTSNPDFTKCFQNTVLVWVPCSYLWVCFPFYFLYLSHHDRGYIQMTHLNKAKT---ALGFLLWIVCWADLFYSFWERSMGKLLAPVFLVSPTLLGITMLLATFLIQIERRRGVQSSGIMLTFWLIALLCALAILRSKIMTALKEDARVDVFRDVT----------FYIYFSLVLIQLVLSCFSDRSPLFSETINDPN-PCPESSASFLSRITFWWITGMMVQGYRQPLESTDLWSLNKEDTSEQVVPVLVKNWKKECAKSRKQPVKIVYSSKDPAKPKGSSKVDVNEEAEALIVKCPQKERDPSLFKVLYKTFGPYFLMS-------FLFKAVHDLMMFAGPEILKLLINFVNDKKAPEWQGYFYTALLFISACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNAARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDENNILDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRVFLSHEDLDPDSIQRRPIKDAGATNSITVKNATFTWA-RNDPPTLHGITFSVPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVTVKGSVAYVPQQAWIQNISLRENILFGRQLQERYYKAVVEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCDSDVYLLDDPLSAVDAHVGKHIFENVIGPK-GLLKNKTRLLVTHAISYLPQMDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYAS-AEQEQGQPE------DGLAGVGGPGKEVKQMENGMLVTDTAGK---QMQRQLSSSSSYSRDVSQHHTSTAELRKP--GPT-------EETWKLVEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFLCNHVASLVSNYWLSLWTDDPIVNGTQEHTQVRLSVYGALGISQGITVFGYSMAVSIGGIFASRRLHLDLLHNVLRSPISFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFNVIGACIIILLATPMAAVIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFASLFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSE-TEKEAPWQI-QDMAPPKDWPQVGRVEFRDYGLRYREDLDLVLKHINVTIDGGEKVGIVGRTGAGKSSLTLGLFRIKESAEGEIIIDDINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFDDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEWGSPSDLLQQ-RGLFYSMAKDSGLV 1530
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. SwissProt
Match: gi|296439301|sp|P33527.3|MRP1_HUMAN (RecName: Full=Multidrug resistance-associated protein 1; AltName: Full=ATP-binding cassette sub-family C member 1; AltName: Full=Leukotriene C(4) transporter; Short=LTC4 transporter) HSP 1 Score: 1207.59 bits (3123), Expect = 0.000e+0 Identity = 679/1574 (43.14%), Postives = 968/1574 (61.50%), Query Frame = 0
Query: 24 GLMKFCH----DPFWDLNTTWFTLDPDFTHCFHQTALVYVPCGLLWLLAPLEIYWINASQSRHIRWNLINVAKCISIALCIILDVISLSLSLGYFGNNTSWLSLSDI--LAPLIVFLTHALALILTLMNKKMGLTSSGILFTFWFVLVITSGLTFASVVRFGAFRTITSSWSVE--QSMIYTIYFPLVVAISFLTFWADPPPVYWEVEDQVDVPSPEMYASFPSKIAFGWIDTLIKMGWQTPLNQRNIFDLNPNLTTN----ILTKKWAKHEKKVR-HPMR------------GTLKTD--------------------LIQTLARCFGVDFLIASGLQILGVLINQVFFVCCKAVPQTISLLITF-STSDEPLWRGYLYMSLLVAINMIRTLLNTQYFFIYLVLGQNVRTTLISAIYRKTFKLSASSRRQRSVGETVNLMSIDTERMNIVVGSLNNLWYAPLVILLSLYFLWGYLGPSCLAGLGMMIILIPINAWLSSRIKKYQFANMKKKDQRLETMNEVLEGIKVMKLYAWEPSFQEKIAAIRDSEVETLKKISYLGALQTFIFNSAVFLVTLVTFGTYVYLDPSNVLDAEKAFVSISYFNLMRGPLNQFPQFIIQLIQASVSHKRLDEFLNAPETDSKIIGNEP----NSQHAVEVFNGSFAWDDTEDSSTIHGINLKIERGSLVAIVGQVGAGKSSLISAILGDMEKRTGSVNVDGTVAYVPQQAWIQNDTVRQNILFGRDHFPNIYFETVRACALVEDFTILEQGDQTEIGEKGINLSGGQKQRVSLARAVYNNRDIYLLDDPMSAVDAHVGKHIFEHVISSRTGVLKDKTRLLVTHNVTFLHETDLILVMKNGRISEMGTFNDLMSGGGDFSLFLAEYGNIS-EQDA---------GSVEQVETFQDTLDMVSNLSQNELNKTPPDPSSPAFLDLNSPLGSTIGSVKIRKRNSAKTFRKRKGKVGPSSSNKTNSREKGKLVVEEKLETSAVSNAVYVYYAKAIGLFVTITIFGLYAVNQAFSVGTNVWLAKWSDDP-QSAIPKYRDMYLGGYGGLGGASALTVMVVYLIITIGGLNASTKLHNNLLAKILAAPMSFFDTNPKGRILNRFGKDVDAVDTNVPSNFNSICRLLFNTFGTIVVICATNPLFIVVFIPLFLAYWFIQKLYITTSRQLKRLNSIARSPIYSLFGETLSGVPTIKAFNLQDQLIKINESKVDTLQTTTYLNQAANRWLSVRLEMLGNVVILFAALFAVLGRDKVDPGEVGLSLSYATQITTFLTFLIRMMSMIENNMVSVERIQEYEDHVDQEAPYVCPMESTLEKQWPPRGAIRFQDYKTRYRPGLDLVLKGITCDIHAGEKIGIVGRTGAGKSSLTMALFRLIEPSSGTIYIDGTDITTLGLGFLRSNITIIPQDPVLFSGTMRLNLDPFEIATDDQIWRALKLGHLSEYVSGLRYGLDQEISEGGGNLSVGQRQLVCLARALLRKTQILVLDEATAAVDLEMDDLIQTTIRQEFKDCTILTIAHRLNTIMDCDRVIVLRSGLIAEMDEPQKLLQDTNSIFFGMAKNAGLM 1536
L FC DP WD N TW T +PDFT CF T LV+VPC LW P +++ +I+ +N K AL +L ++ + F + + L+ + ++P ++ +T LA L + ++ G+ SSGI+ TFW V ++ + +++R + V+ + + + +YF L++ L+ ++D P++ E + P PE ASF S+I F WI LI G++ PL +++ LN T+ +L K W K K R P++ + K D L + L + FG FL++ + + L+ +F + PQ + LLI F + + P W+GY Y LL ++TL+ QYF I V G ++T +I A+YRK ++ S+R+ +VGE VNLMS+D +R + +N +W APL ++L+LY LW LGPS LAG+ +M++++P+NA ++ + K YQ A+MK KD R++ MNE+L GIKV+KLYAWE +F++K+ AIR E++ LKK +YL A+ TF + FLV L TF YV +D +N+LDA+ AFVS++ FN++R PLN P I ++QASVS KRL FL+ E + I P +++ V N +F W + D T++GI I G+LVA+VGQVG GKSSL+SA+L +M+K G V + G+VAYVPQQAWIQND++R+NILFG Y ++ACAL+ D IL GD+TEIGEKG+NLSGGQKQRVSLARAVY+N DIYL DDP+SAVDAHVGKHIFE+VI + G+LK+KTR+LVTH++++L + D+I+VM G+ISEMG++ +L++ G F+ FL Y + EQDA G ++ + ++ + +V++ + +L + L +S I R NS +K + K E KL+ +K +T V +VY Y KAIGLF++ L+ N ++ +N WL+ W+DDP + ++ + L YG LG + + V + ++IGG+ AS LH +LL IL +PMSFF+ P G ++NRF K++D VD+ +P LFN G +VI P+ ++ PL L Y+F+Q+ Y+ +SRQLKRL S++RSP+YS F ETL GV I+AF Q++ I ++ KVD Q Y + ANRWL+VRLE +GN ++LFAALFAV+ R + G VGLS+SY+ Q+TT+L +L+RM S +E N+V+VER++EY + ++EAP+ E+ WP G + F++Y RYR LD VL+ I I+ GEK+GIVGRTGAGKSSLT+ LFR+ E + G I IDG +I +GL LR ITIIPQDPVLFSG++R+NLDPF +D+++W +L+L HL ++VS L LD E +EGG NLSVGQRQLVCLARALLRKT+ILVLDEATAAVDLE DDLIQ+TIR +F+DCT+LTIAHRLNTIMD RVIVL G I E P LLQ +F+ MAK+AGL+
Sbjct: 2 ALRGFCSADGSDPLWDWNVTWNTSNPDFTKCFQNTVLVWVPCFYLWACFPFYFLYLSRHDRGYIQMTPLNKTKT---ALGFLLWIVCWADLFYSFWERSRGIFLAPVFLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALVCA----LAILRSKIMTALKEDAQVDLFRDITFYVYFSLLLIQLVLSCFSDRSPLFSETIHDPN-PCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEALIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLM--MF-----SGPQILKLLIKFVNDTKAPDWQGYFYTVLLFVTACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYVTIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGTNSITVRNATFTWARS-DPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPK-GMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASTEQEQDAEENGVTGVSGPGKEAKQMENGM-LVTDSAGKQLQRQ---------LSSSSSYSGDIS----RHHNSTAELQKAEAK----------KEETWKLMEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFMCNHVSALASNYWLSLWTDDPIVNGTQEHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSE-TEKEAPWQI-QETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQ-RGLFYSMAKDAGLV 1531 HSP 2 Score: 89.7373 bits (221), Expect = 1.833e-16 Identity = 95/401 (23.69%), Postives = 175/401 (43.64%), Query Frame = 0
Query: 1156 LFGETLSGVPTIKAFN----LQDQLIKINESKVDTLQTTTYLNQAAN-RWLSVRLEMLGNVVILFAALFAVLGRDKVDPGEVGLSLSYATQITTFLTFLIRMMSMIENNMVSVERIQEYEDHVDQEAPYVCPMESTLEKQWPPRGAIRFQDYKTRYRPGLDLVLKGITCDIHAGEKIGIVGRTGAGKSSLTMALFRLIEPSSGTIYIDGTDITTLGLGFLRSNITIIPQDPVLFSGTMRLNLDPFEIATDDQIWRA-LKLGHLSEYVSGLRYGLDQEISEGGGNLSVGQRQLVCLARALLRKTQILVLDEATAAVDLEMDDLIQTTI---RQEFKDCTILTIAHRLNTIMDCDRVIVLRSGLIAEMDEPQKLLQDTNSIFFGMAKNAGLMSEQEAKRQRVS 1547
L E L+G+ +K + +D+++ I + ++ L+ + YL+ W+ + + FA + + +D +SL+ + L L ++S I VS++R++ + H + E + E K +I ++ + L GIT I G + +VG+ G GKSSL AL ++ G + I G+ + +PQ + + ++R N+ F ++ +R+ ++ L + L G EI E G NLS GQ+Q V LARA+ I + D+ +AVD + I + + K+ T + + H ++ + D +IV+ G I+EM Q+LL + + A EQ+A+ V+
Sbjct: 504 LMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLSAVGTFTWVCTPFLV---ALCTFAVYVTIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSI---ERRPVKDGGGTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGS-------------VAYVPQQAWIQNDSLRENI-LFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASTEQEQDAEENGVT 884
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. SwissProt
Match: gi|6920069|sp|O15438.3|MRP3_HUMAN (RecName: Full=Canalicular multispecific organic anion transporter 2; AltName: Full=ATP-binding cassette sub-family C member 3; AltName: Full=Multi-specific organic anion transporter D; Short=MOAT-D; AltName: Full=Multidrug resistance-associated protein 3) HSP 1 Score: 1198.73 bits (3100), Expect = 0.000e+0 Identity = 664/1550 (42.84%), Postives = 957/1550 (61.74%), Query Frame = 0
Query: 33 FWDLNTTWFTLDPDFTHCFHQTALVYVPCGLLWLLAPLEIYWINASQSRHIRWNLI--NVAKCISIALCIILDVISLSLSLGYFGNNTSWLSLSDI--LAPLIVFLTHALALILTLMNKKMGLTSSGILFTFWFVLVITSGLTFASVVRFG--------AFRTITSSWSVEQSMIYTIYFPLVVAISFLTFWADPPPVYWEVEDQVDVPSPEMYASFPSKIAFGWIDTLIKMGWQTPLNQRNIFDLN----PNLTTNILTKKWAKHEKK-VRHPMRGT-------------------LKTDLIQTLARCFGVDFLIASGLQILGVLINQVFFVCCKAVPQTISLLITF-STSDEPLWRGYLYMSLLVAINMIRTLLNTQYFFIYLVLGQNVRTTLISAIYRKTFKLSASSRRQRSVGETVNLMSIDTERMNIVVGSLNNLWYAPLVILLSLYFLWGYLGPSCLAGLGMMIILIPINAWLSSRIKKYQFANMKKKDQRLETMNEVLEGIKVMKLYAWEPSFQEKIAAIRDSEVETLKKISYLGALQTFIFNSAVFLVTLVTFGTYVYLDPSNVLDAEKAFVSISYFNLMRGPLNQFPQFIIQLIQASVSHKRLDEFLNAPETDSKIIGNEPNSQ-HAVEVFNGSFAWDDTEDSSTIHGINLKIERGSLVAIVGQVGAGKSSLISAILGDMEKRTGSVNVDGTVAYVPQQAWIQNDTVRQNILFGRDHFPNIYFETVRACALVEDFTILEQGDQTEIGEKGINLSGGQKQRVSLARAVYNNRDIYLLDDPMSAVDAHVGKHIFEHVISSRTGVLKDKTRLLVTHNVTFLHETDLILVMKNGRISEMGTFNDLMSGGGDFSLFLAEYGNISEQDAGSVEQVET-FQDTLDMVSNLSQNELNKTPPDPSSPAFLDLNSPLGSTIGSVKIRKRNSAKTFRKRKGK------VGPSSSNK-TNSREKGKLVVEEKLETSAVSNAVYVYYAKAIGLFVTITIFGLYAVNQAFSVGTNVWLAKWSDDPQS-AIPKYRDMYLGGYGGLGGASALTVMVVYLIITIGGLNASTKLHNNLLAKILAAPMSFFDTNPKGRILNRFGKDVDAVDTNVPSNFNSICRLLFNTFGTIVVICATNPLFIVVFIPLFLAYWFIQKLYITTSRQLKRLNSIARSPIYSLFGETLSGVPTIKAFNLQDQLIKINESKVDTLQTTTYLNQAANRWLSVRLEMLGNVVILFAALFAVLGRDKVDPGEVGLSLSYATQITTFLTFLIRMMSMIENNMVSVERIQEYEDHVDQEAPYVCPMESTLEKQWPPRGAIRFQDYKTRYRPGLDLVLKGITCDIHAGEKIGIVGRTGAGKSSLTMALFRLIEPSSGTIYIDGTDITTLGLGFLRSNITIIPQDPVLFSGTMRLNLDPFEIATDDQIWRALKLGHLSEYVSGLRYGLDQEISEGGGNLSVGQRQLVCLARALLRKTQILVLDEATAAVDLEMDDLIQTTIRQEFKDCTILTIAHRLNTIMDCDRVIVLRSGLIAEMDEPQKLLQDTNSIFFGMAKNAGL 1535
FWD N + T +PD T CF + L +VPC LW+ P + ++ H R +I +++K + + L ++L +S + F + + + + PL+V +T LA +L + G+ SSG+L FWF+ V+ + + F S + FR T + I+F LV++ L + + PP ++ ++ P PE A F S++ F W + G++ PL +++++ L + L + W K EK+ RH K ++ L FG FLI++ +++ L++ + PQ +S+LI F S P W G+L L+ +M+++L+ Y+ V G RT ++ IYRK ++ S +R +VGE VNLMS+D +R + LN LW APL I+L++YFLW LGPS LAG+ M++LIP+N ++ +++ +Q MK KD R++ M+E+L GIKV+KLYAWEPSF +++ IR E++ L+ +YL TF + + FLVTL+T YVY+DP+NVLDAEKAFVS+S FN++R PLN PQ I L QASVS KR+ +FL+ E D + + + S +A+ + +G+F W + T+H +++++ +G+LVA+VG VG GKSSL+SA+LG+MEK G V++ G+VAYVPQQAWIQN T+++N+LFG+ P Y +T+ ACAL+ D +L GDQTEIGEKGINLSGGQ+QRVSLARAVY++ DI+LLDDP+SAVD+HV KHIF+HVI GVL KTR+LVTH ++FL +TD I+V+ +G++SEMG + L+ G F+ FL Y ++D G +E T + D + L ++ L S+ L N P+ + +R+ ++ + + +G+ +GPS + T ++ G L EEK V +V+ YAKA+GL T+ I LY A ++G NVWL+ W++D + + + LG Y LG VM+ + + GG+ A+ LH LL + +P SFFDT P GRILN F KD+ VD + + FN T+VVI A+ PLF VV +PL + Y +Q+ Y TSRQLKRL S++RSPIYS F ET++G I+A+N I+++KVD Q + Y +NRWLS+ +E +GN V+LFAALFAV+GR ++PG VGLS+SY+ Q+T L ++IRMMS +E+N+V+VER++EY + EAP+V E WPPRG + F++Y RYRPGLDLVL+ ++ +H GEK+GIVGRTGAGKSS+T+ LFR++E + G I IDG ++ +GL LRS +TIIPQDP+LFSGT+R+NLDPF +++ IW AL+L HL +VS GLD + SEGG NLSVGQRQLVCLARALLRK++ILVLDEATAA+DLE D+LIQ TIR +F CT+LTIAHRLNTIMD RV+VL G++AE D P L+ IF+GMA++AGL
Sbjct: 14 FWDSNLSVHTENPDLTPCFQNSLLAWVPCIYLWVALPCYLLYLR----HHCRGYIILSHLSK-LKMVLGVLLWCVSWADLFYSFHGLVHGRAPAPVFFVTPLVVGVTMLLATLLIQYERLQGVQSSGVLIIFWFLCVVCAIVPFRSKILLAKAEGEISDPFRFTT----------FYIHFALVLSALILACFREKPP-FFSAKNVDPNPYPETSAGFLSRLFFWWFTKMAIYGYRHPLEEKDLWSLKEEDRSQMVVQQLLEAWRKQEKQTARHKASAAPGKNASGEDEVLLGARPRPRKPSFLKALLATFGSSFLISACFKLIQDLLSFI-------NPQLLSILIRFISNPMAPSWWGFLVAGLMFLCSMMQSLILQHYYHYIFVTGVKFRTGIMGVIYRKALVITNSVKRASTVGEIVNLMSVDAQRFMDLAPFLNLLWSAPLQIILAIYFLWQNLGPSVLAGVAFMVLLIPLNGAVAVKMRAFQVKQMKLKDSRIKLMSEILNGIKVLKLYAWEPSFLKQVEGIRQGELQLLRTAAYLHTTTTFTWMCSPFLVTLITLWVYVYVDPNNVLDAEKAFVSVSLFNILRLPLNMLPQLISNLTQASVSLKRIQQFLSQEELDPQSVERKTISPGYAITIHSGTFTWAQ-DLPPTLHSLDIQVPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGKVHMKGSVAYVPQQAWIQNCTLQENVLFGKALNPKRYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLLDDPLSAVDSHVAKHIFDHVIGPE-GVLAGKTRVLVTHGISFLPQTDFIIVLADGQVSEMGPYPALLQRNGSFANFLCNYA--PDEDQGHLEDSWTALEGAEDKEALLIEDTL-------SNHTDLTDNDPVTYVVQKQFMRQLSALSSDGEGQGRPVPRRHLGPSEKVQVTEAKADGALTQEEKAAIGTVELSVFWDYAKAVGLCTTLAICLLYVGQSAAAIGANVWLSAWTNDAMADSRQNNTSLRLGVYAALGILQGFLVMLAAMAMAAGGIQAARVLHQALLHNKIRSPQSFFDTTPSGRILNCFSKDIYVVDEVLAPVILMLLNSFFNAISTLVVIMASTPLFTVVILPLAVLYTLVQRFYAATSRQLKRLESVSRSPIYSHFSETVTGASVIRAYNRSRDFEIISDTKVDANQRSCYPYIISNRWLSIGVEFVGNCVVLFAALFAVIGRSSLNPGLVGLSVSYSLQVTFALNWMIRMMSDLESNIVAVERVKEYSK-TETEAPWVVEGSRPPEG-WPPRGEVEFRNYSVRYRPGLDLVLRDLSLHVHGGEKVGIVGRTGAGKSSMTLCLFRILEAAKGEIRIDGLNVADIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGSYSEEDIWWALELSHLHTFVSSQPAGLDFQCSEGGENLSVGQRQLVCLARALLRKSRILVLDEATAAIDLETDNLIQATIRTQFDTCTVLTIAHRLNTIMDYTRVLVLDKGVVAEFDSPANLIA-ARGIFYGMARDAGL 1526
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. nr
Match: gi|586962508|gb|AHK05642.1| (ATP-binding cassette transporter sub-family C member 1 isoform X4 [Tigriopus japonicus]) HSP 1 Score: 2014.96 bits (5219), Expect = 0.000e+0 Identity = 996/1519 (65.57%), Postives = 1212/1519 (79.79%), Query Frame = 0
Query: 26 MKFCHDPFWDLNTTWFTLDPDFTHCFHQTALVYVPCGLLWLLAPLEIYWINASQSRHIRWNLINVAKCISIALCIILDVISLSLSLGYFGNNTSWLSLSDILAPLIVFLTHALALILTLMNKKMGLTSSGILFTFWFVLVITSGLTFASVVRFGAFRTITSSWSVEQSMIYTIYFPLVVAISFLTFWADPPPVYWEVEDQVDVPSPEMYASFPSKIAFGWIDTLIKMGWQTPLNQRNIFDLNPNLTTNILTKKWAKHEKKVRHPMRGTLKTDLIQTLARCFGVDFLIASGLQILGVLINQVFFVCCKAVPQTISLLITFSTSDEPLWRGYLYMSLLVAINMIRTLLNTQYFFIYLVLGQNVRTTLISAIYRKTFKLSASSRRQRSVGETVNLMSIDTERMNIVVGSLNNLWYAPLVILLSLYFLWGYLGPSCLAGLGMMIILIPINAWLSSRIKKYQFANMKKKDQRLETMNEVLEGIKVMKLYAWEPSFQEKIAAIRDSEVETLKKISYLGALQTFIFNSAVFLVTLVTFGTYVYLDPSNVLDAEKAFVSISYFNLMRGPLNQFPQFIIQLIQASVSHKRLDEFLNAPETDSKIIGNEPNSQHAVEVFNGSFAWDDTEDSSTIHGINLKIERGSLVAIVGQVGAGKSSLISAILGDMEKRTGSVNVDGTVAYVPQQAWIQNDTVRQNILFGRDHFPNIYFETVRACALVEDFTILEQGDQTEIGEKGINLSGGQKQRVSLARAVYNNRDIYLLDDPMSAVDAHVGKHIFEHVISSRTGVLKDKTRLLVTHNVTFLHETDLILVMKNGRISEMGTFNDLMSGGGDFSLFLAEYGNISEQDAGSVEQVETFQDTLDMVSNLSQNELNKTP----PDPSSPAFLD---LNSPLGSTIG-SVKIRKRNSAKTFRKRKGKVGPSSSNKTNSREKGKLVVEEKLETSAVSNAVYVYYAKAIGLFVTITIFGLYAVNQAFSVGTNVWLAKWSDDPQSAIPKYRDMYLGGYGGLGGASALTVMVVYLIITIGGLNASTKLHNNLLAKILAAPMSFFDTNPKGRILNRFGKDVDAVDTNVPSNFNSICRLLFNTFGTIVVICATNPLFIVVFIPLFLAYWFIQKLYITTSRQLKRLNSIARSPIYSLFGETLSGVPTIKAFNLQDQLIKINESKVDTLQTTTYLNQAANRWLSVRLEMLGNVVILFAALFAVLGRDKVDPGEVGLSLSYATQITTFLTFLIRMMSMIENNMVSVERIQEYEDHVDQEAPYVCPMESTLEKQWPPRGAIRFQDYKTRYRPGLDLVLKGITCDIHAGEKIGIVGRTGAGKSSLTMALFRLIEPSSGTIYIDGTDITTLGLGFLRSNITIIPQDPVLFSGTMRLNLDPFEIATDDQIWRALKLGHLSEYVSGLRYGLDQEISEGGGNLSVGQRQLVCLARALLRKTQILVLDEATAAVDLEMDDLIQTTIRQEFKDCTILTIAHRLNTIMDCDRVIVLRSGLIAEMDEPQKLLQDTNSIFFGMAKNAGLM 1536
MKFC+ PFWD+N TW T +PDF CFHQT LVYVPC LWLL P+E+ WIN+SQSR++ WN IN+AK + I +C+ILD+I+LS L G ++ +++SD+L LI+ T LAL LT +NK+MGLT+S ILF FW++LV+ TFASV+RFGA T W++EQS+IYT Y+ +VA +FL WADPPP YW++E QV+ PSPE++ASFPSK+ F W++ L KMGW+TPLN N++DL P+L + LTK+W + +K P+ K + +TL R F + FL A+ Q+L +++NQ+ PQ +SLLI+++TS EP W+GYLYM+L+V +NM++TL + FF++ V+GQNVRT LISAIY KTF LS+SSRRQRSVGETVNLMSID+ER++ ++GSLN +WY+P VI+LSL FLW Y+GPSCLAGLG+MIILIP+NA LS++IKKYQ NM+KKD RLE MNE+L+GIKVMKLYAWEPSF +K++ +RD EVETLKKISYLGA+QT +FNSAVFLVTL TF TYV +DPSN+LDA+KAFVSISYFNLMR PLNQ P IIQ IQA VSHKRLD FLNAPE D I N+P+++ A+ + +GSFAWD S++ INLK++RGSLVAIVGQVG+GKSSLISAILGDM+K +GSVNVDG+VAYVPQQAWIQN +VR NI FGR++F NIY E V+ACAL EDF IL+ GDQTEIGEKGINLSGGQKQRVSLARAVYNNRDIYL DDP+SAVDAHVG HIF V+SSRTGVL++KTR+LVTH+++ L E D+I+V+KNG I+EMGT+ +L+S G FS FLAEYG Q VE +ETF++T+D + ++N +P +P+ F NS T+G ++ +RKR + + + P K SR+K KL+VEEKLET AVS VY+YYA+AIG+ VT +I LYAVNQ FSVGTNVWLAKWSDDP SAIP R++YLG YG LGGASA+T+MVVYLI+TIGGLNASTKLHNN+L +LAAPM FFDTNPKGR+LNRF KDVDAVD++VP NFN + LFNT GTI +IC TNP+FI +FIPLF+ Y+FIQK+YI TSRQ+KRLNSIARSPIYSLFGETLSGV TIKAF LQ I+ N VD + YLN AANRWLS+RLEMLGNVVILFA+LFAVLG+D ++PG VGLSLSYA QIT L FLIR++S IENNMVSVERIQEYE VDQEA Y + + K WPP+GAIRFQDYKTRYRPGLDLVL+G+TCDI AGEK+GIVGRTGAGKSSLTMALFR+IEP+SG+I+IDG +I +LGLGFLRS+ITIIPQDPVLFSG+MR NLDPF +D IW+AL+L HL +YVS L+ GLD EI+EGG NLSVGQ+QLVCLARALLRKTQIL+LDEATAAVDLE DDLIQTTIR+EF +CTILTIAHRLNTIMDCD++IVL +G+IAEM P LLQD SIF+ MA+NAGL+
Sbjct: 1 MKFCNTPFWDINQTWNTEEPDFPLCFHQTVLVYVPCLFLWLLTPVELCWINSSQSRNVLWNPINIAKFLCIGVCLILDLINLSFILVQLGTSSDIVAISDVLRSLILVCTLGLALTLTFLNKRMGLTTSAILFLFWWLLVLCFSPTFASVIRFGAIATPRPMWNMEQSVIYTFYYAFLVATAFLNCWADPPPTYWQIEKQVETPSPELFASFPSKVLFSWMNGLFKMGWKTPLNGNNMYDLKPDLMSRFLTKRWNRLKKFKMDPVAYEPKVSIYKTLGRSFWLSFLWATFFQVLTLILNQL-------SPQILSLLISYTTSSEPEWKGYLYMTLMVVVNMLKTLTLSHNFFMFTVIGQNVRTMLISAIYEKTFLLSSSSRRQRSVGETVNLMSIDSERVSTIIGSLNTIWYSPTVIILSLAFLWEYVGPSCLAGLGVMIILIPVNAILSAKIKKYQVINMRKKDARLEVMNEILDGIKVMKLYAWEPSFAQKVSKVRDEEVETLKKISYLGAVQTLLFNSAVFLVTLATFATYVLVDPSNILDAQKAFVSISYFNLMRVPLNQLPMLIIQAIQALVSHKRLDSFLNAPEIDEDAITNDPDNKVAIHIQDGSFAWDH---DSSLQNINLKVKRGSLVAIVGQVGSGKSSLISAILGDMQKISGSVNVDGSVAYVPQQAWIQNASVRDNITFGREYFENIYKEAVKACALEEDFLILDDGDQTEIGEKGINLSGGQKQRVSLARAVYNNRDIYLFDDPLSAVDAHVGNHIFREVMSSRTGVLRNKTRVLVTHSLSVLSEVDMIIVLKNGTITEMGTYEELVSSQGAFSFFLAEYGTTLPQSLNEVEGMETFKETIDTIMLRNKNGPKHSPLTHQDEPTHVIFGQKKRRNSASSGTMGNALSLRKRKVSHDSKTKPSTERPKRKPKI-SRKK-KLIVEEKLETKAVSIEVYLYYARAIGICVTFSILLLYAVNQGFSVGTNVWLAKWSDDPNSAIPSIRNLYLGIYGLLGGASAVTIMVVYLIVTIGGLNASTKLHNNILTTVLAAPMMFFDTNPKGRVLNRFSKDVDAVDSSVPGNFNGFFKFLFNTCGTIAIICFTNPIFIAIFIPLFVCYYFIQKVYIATSRQIKRLNSIARSPIYSLFGETLSGVVTIKAFKLQGNFIEQNHGMVDNFMASNYLNFAANRWLSIRLEMLGNVVILFASLFAVLGKDVMNPGVVGLSLSYAMQITGSLNFLIRLVSQIENNMVSVERIQEYEMDVDQEASYALVTDPSDGKTWPPQGAIRFQDYKTRYRPGLDLVLRGVTCDIEAGEKVGIVGRTGAGKSSLTMALFRMIEPASGSIFIDGVNICSLGLGFLRSHITIIPQDPVLFSGSMRQNLDPFGHFSDPDIWKALELSHLGQYVSSLKMGLDHEIAEGGSNLSVGQKQLVCLARALLRKTQILILDEATAAVDLETDDLIQTTIRKEFSECTILTIAHRLNTIMDCDKIIVLSNGIIAEMGSPSILLQDQRSIFYDMAQNAGLV 1507
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. nr
Match: gi|586962504|gb|AHK05640.1| (ATP-binding cassette transporter sub-family C member 1 isoform X2 [Tigriopus japonicus]) HSP 1 Score: 1420.22 bits (3675), Expect = 0.000e+0 Identity = 745/1535 (48.53%), Postives = 1008/1535 (65.67%), Query Frame = 0
Query: 27 KFCHDPFWDLNTTWFTLDPDFTHCFHQTALVYVPCGLLWLLAPLEIYW-INASQSRHIRWNLINVAKCISIALCIILDVISLSLSLGYFGNNTSWLSLSDILAPLIVFLTHALALILTLMNKKMGLTSSGILFTFWFVLVITSGLTFASVVRFGAFRTITSSWSVEQSMI----YTIYFPLVVAISFLTFWADPPPVYWEVEDQVDVPSPEMYASFPSKIAFGWIDTLIKMGWQTPLNQRNIFDLNPNLTTNILT----KKWAKHEKKVRHPMRGTLKTDLIQTLARCFGVDFLIASGLQILGVLINQVFFVCCKAVPQTISLLITFSTSDEPLWRGYLYMSLLVAINMIRTLLNTQYFFIYLVLGQNVRTTLISAIYRKTFKLSASSRRQRSVGETVNLMSIDTERMNIVVGSLNNLWYAPLVILLSLYFLWGYLGPSCLAGLGMMIILIPINAWLSSRIKKYQFANMKKKDQRLETMNEVLEGIKVMKLYAWEPSFQEKIAAIRDSEVETLKKISYLGALQTFIFNSAVFLVTLVTFGTYVYLDPSNVLDAEKAFVSISYFNLMRGPLNQFPQFIIQLIQASVSHKRLDEFLNAPETDSKIIGNEPNSQHAVEVFNGSFAWDDTEDSSTIHGINLKIERGSLVAIVGQVGAGKSSLISAILGDMEKRTGSVNVDGTVAYVPQQAWIQNDTVRQNILFGRDHFPNIYFETVRACALVEDFTILEQGDQTEIGEKGINLSGGQKQRVSLARAVYNNRDIYLLDDPMSAVDAHVGKHIFEHVISSRTGVLKDKTRLLVTHNVTFLHETDLILVMKNGRISEMGTFNDLMSGGGDFSLFLAEYGNISEQDAGSVEQVETFQDTLDMVSNLSQNELNKTPPDPSSPAFLDLNSPLGSTIGSVKIRKRNSAKTFRKRKG-----KVGPSSSNKT-NSREKG--------KLVVEEKLETSAVSNAVYVYYAKAIGLFVTITIFGLYAVNQAFSVGTNVWLAKWSDDPQSAI-PKYRDMYLGGYGGLGGASALTVMVVYLIITIGGLNASTKLHNNLLAKILAAPMSFFDTNPKGRILNRFGKDVDAVDTNVPSNFNSICRLLFNTFGTIVVICATNPLFIVVFIPLFLAYWFIQKLYITTSRQLKRLNSIARSPIYSLFGETLSGVPTIKAFNLQDQLIKINESKVDTLQTTTYLNQAANRWLSVRLEMLGNVVILFAALFAVLGRDKVDPGEVGLSLSYATQITTFLTFLIRMMSMIENNMVSVERIQEYEDHVDQEAPYVCPMESTLEKQWPPRGAIRFQDYKTRYRPGLDLVLKGITCDIHAGEKIGIVGRTGAGKSSLTMALFRLIEPSSGTIYIDGTDITTLGLGFLRSNITIIPQDPVLFSGTMRLNLDPFEIATDDQIWRALKLGHLSEYVSGLRYGLDQEISEGGGNLSVGQRQLVCLARALLRKTQILVLDEATAAVDLEMDDLIQTTIRQEFKDCTILTIAHRLNTIMDCDRVIVLRSGLIAEMDEPQKLLQDTNSIFFGMAKNAGLMS 1537
+FC P WD+N TW T DPDFT CFHQT L+Y+P G L L +PLE+Y+ I ++ + W L+N+AK I + +IL VI L GY N + ++A ++ +T+ AL L + +++ G+ +SG+L FWF+ I +TFASV+ T S + M+ YT+ FPL++ + FL WAD P Y ++E+ V +PE +ASF S+ F W D GW+ L +++DL + + + ++W K+ K + + + TL + FG + I S L LG + Q A PQ ++L+I F SD+P+W+GYLY L+ + T+LN Q F+ +G ++T LISAIYRK+ KLS S R+ +VGET NLMSIDT++ + LN +W +PL I L++YFLW LGPS LAGL +M+++IP+NA ++ ++KKYQ A MK KD+R M+E+L GIKV+KLYAWEPSF++ + IR E+ LKK +YL + TF++ A LV L +F TYV D +N+LDA AFVS++ FNL+R PLN P ++ L+Q VS R++ F+N+ E + PN++ A+ V +FAWD + + INL ++ G LVA+VG VGAGKSSL+SA LG+ME+ GS+ +G VAYVPQQAW++N +++ NILF + + N+Y + +CALV D +L GD+TEIGEKGINLSGGQKQRVS+ARAVY+NRD+YLLDDP+SAVD+HVGKHIFE+VI G+LK KTR+LVTH V+FL + D ILVMK+GRISE GT+ +L++ GDF+ FL +Y ++E+ G E+ + L+ + + L K A + + L I + ++ + +KR ++ P SSN E+G L+ +EK E V ++Y YYAK+IG ++ Y + Q F +G NVWL++WS DP++ RDMYLG YG LG +L +M + +G LNA+ KLH+ +L +IL +PMSFFDT P GRILNRF KD+D +D +P N + FN GT+VVIC NP+FI V IP+ L Y+F+QK Y+TT+RQ+KR+ SI RSPIYS FGET+SG PTI+A+ + I NE K+D Q Y ++RWLSVRLE++GN+VILFA+LFAVL RD +DPG+VGLSLSYA IT + L+RM S +E NMVSVERI EY++ QEAP P E +WP G ++F +Y+TRYR GLDLVLKGI+ I +GEKIGIVGRTGAGKSSLT+ALFR+IE + G+IYID +I LGL LRS +TIIPQDPVLFSG+MRLNLDPFE +D +IWRAL HL YVS L GL +++EGG NLSVGQRQLVCLARALLRKT++LVLDEATAAVDLE DDLIQTTIR EF DCT+LTIAHRLNTIMD +V+VL +G I E D P+ L+ +SIF+GMA +AGL++
Sbjct: 6 EFCGGPIWDVNVTWNTKDPDFTTCFHQTILLYIPTGFLVLFSPLEVYFRIYRGSNKPVPWTLLNIAKLILNGILVILPVIDL----GYAINEDA--RTVHVVAAIVKIVTYVCALCLAVASQRRGVVTSGLLVIFWFLAAIGGAITFASVLS-------TPYLSGDHFMLPFLSYTLQFPLILVLFFLNCWADAPSKYKKLEEDVPNLTPEKHASFFSRAIFAWFDPFAWKGWRRTLEYTDLWDLKKSERCSGIVPEWDRQWEKNVIKTIQNSKAPSQVSITSTLMKSFGPAYAI-SALYQLGTSVLQF------ASPQIVNLIIDFVESDQPVWKGYLYTGLICLSTLFNTILNNQCFYQEYTVGLRIKTALISAIYRKSVKLSNSGRKVMTVGETTNLMSIDTQKFMDLTLYLNMIWASPLQIALAMYFLWDILGPSSLAGLAVMVLMIPLNAVVAQQMKKYQHAQMKDKDRRTRLMDEILNGIKVLKLYAWEPSFEKHVVDIRAREISALKKSAYLNSFTTFLWTCAPVLVALASFATYVLSDSANILDANTAFVSLTLFNLLRVPLNMLPMLLVFLVQCEVSLTRINTFMNSDELRVNAVDRNPNAKGAIVVKKATFAWDKDAEP-VLRDINLTVKEGELVAVVGTVGAGKSSLLSAFLGEMERLGGSIKTNGKVAYVPQQAWMKNASLKDNILFSKSYKSNLYDRVLNSCALVTDLEMLPGGDETEIGEKGINLSGGQKQRVSIARAVYSNRDLYLLDDPLSAVDSHVGKHIFENVIGPH-GLLKKKTRVLVTHGVSFLPQVDNILVMKDGRISERGTYEELLNKQGDFASFLIQY--LTEE--GDKEKGLEEESELEDLKQELEKTLGKEAVQRQLMASKSVLTSLTDLISESSEKGQHFNQKGKKRSSLMSTSRIHPFSSNSNIPPSERGLDEIKVGQNLIEKEKAEIGGVKWSIYRYYAKSIGTKWSLVTILFYVIYQGFQLGANVWLSEWSTDPRATTDTSVRDMYLGVYGVLGLLQSLAIMTGTCFVMVGTLNAAAKLHSTMLHRILRSPMSFFDTTPLGRILNRFSKDIDIIDVTIPMNIRMLLNQSFNVLGTLVVICFANPIFIAVVIPIILMYYFLQKFYVTTARQVKRMESITRSPIYSHFGETISGAPTIRAYEMVQDFITENEKKIDYNQKCYYPTYVSSRWLSVRLELIGNLVILFASLFAVLFRDTMDPGKVGLSLSYALNITGPMNMLVRMTSEVETNMVSVERISEYQE-TPQEAPLEIP-EQDPPPEWPQYGVVKFDNYQTRYREGLDLVLKGISVQIESGEKIGIVGRTGAGKSSLTLALFRIIESAGGSIYIDNENIGLLGLSKLRSRLTIIPQDPVLFSGSMRLNLDPFEQYSDREIWRALSHAHLKSYVSNLPGGLSFDVNEGGENLSVGQRQLVCLARALLRKTKVLVLDEATAAVDLETDDLIQTTIRAEFSDCTVLTIAHRLNTIMDSSKVLVLDAGQIKEFDTPENLMAQRDSIFYGMANDAGLIN 1512
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. nr
Match: gi|1317163425|ref|XP_023245525.1| (multidrug resistance-associated protein 1 isoform X6 [Copidosoma floridanum]) HSP 1 Score: 1394.02 bits (3607), Expect = 0.000e+0 Identity = 733/1549 (47.32%), Postives = 1008/1549 (65.07%), Query Frame = 0
Query: 27 KFCHDPFWDLNTTWFTLDPDFTHCFHQTALVYVPCGLLWLLAPLEIYWINASQSRHIRWNLINVAKCISIALCIILDVISLSLSL-GYFGNNTSWLSLSDILAPLIVFLTHALALILTLMNKKMGLTSSGILFTFWFVLVITSGLTFASVVRFGAFRTITSSWSVEQSMIYTIYFPLVVAISFLTFWADPPPVYWEVEDQVDVPSPEMYASFPSKIAFGWIDTLIKMGWQTPLNQRNIFDLNPNLTTN----ILTKKWAKHEKKVRHPM-------RGTLKTD-----------LIQTLARCFGVDFLIASGLQILGVLINQVFFVCCKAVPQTISLLITFSTS-DEPLWRGYLYMSLLVAINMIRTLLNTQYFFIYLVLGQNVRTTLISAIYRKTFKLSASSRRQRSVGETVNLMSIDTERMNIVVGSLNNLWYAPLVILLSLYFLWGYLGPSCLAGLGMMIILIPINAWLSSRIKKYQFANMKKKDQRLETMNEVLEGIKVMKLYAWEPSFQEKIAAIRDSEVETLKKISYLGALQTFIFNSAVFLVTLVTFGTYVYLDPSNVLDAEKAFVSISYFNLMRGPLNQFPQFIIQLIQASVSHKRLDEFLNAPETDSKIIGNEPNSQHAVEVFNGSFAWDDTE-DSSTIHGINLKIERGSLVAIVGQVGAGKSSLISAILGDMEKRTGSVNVDGTVAYVPQQAWIQNDTVRQNILFGRDHFPNIYFETVRACALVEDFTILEQGDQTEIGEKGINLSGGQKQRVSLARAVYNNRDIYLLDDPMSAVDAHVGKHIFEHVISSRTGVLKDKTRLLVTHNVTFLHETDLILVMKNGRISEMGTFNDLMSGGGDFSLFLAEYGNISEQDAGSVEQVETFQDTLDMVSNLSQNELNKTPPDPSSPAFLDLNSPLGSTIGSVKIRKRNSAKTFRKRKGKVGPSSS----------NKTNSREKGKLVVEEKLETSAVSNAVYVYYAKAIGLFVTITIFGLYAVNQAFSVGTNVWLAKWSDDPQSAI-----PKYRDMYLGGYGGLGGASALTVMVVYLIITIGGLNASTKLHNNLLAKILAAPMSFFDTNPKGRILNRFGKDVDAVDTNVPSNFNSICRLLFNTFGTIVVICATNPLFIVVFIPLFLAYWFIQKLYITTSRQLKRLNSIARSPIYSLFGETLSGVPTIKAFNLQDQLIKINESKVDTLQTTTYLNQAANRWLSVRLEMLGNVVILFAALFAVLGRDKVDPGEVGLSLSYATQITTFLTFLIRMMSMIENNMVSVERIQEYEDHVDQEAPYVCPMESTLEKQWPPRGAIRFQDYKTRYRPGLDLVLKGITCDIHAGEKIGIVGRTGAGKSSLTMALFRLIEPSSGTIYIDGTDITTLGLGFLRSNITIIPQDPVLFSGTMRLNLDPFEIATDDQIWRALKLGHLSEYVSGLRYGLDQEISEGGGNLSVGQRQLVCLARALLRKTQILVLDEATAAVDLEMDDLIQTTIRQEFKDCTILTIAHRLNTIMDCDRVIVLRSGLIAEMDEPQKLLQDTNSIFFGMAKNAGL 1535
+FC FWD N +W+T +PD T CF +T L++VPC LW+ + E Y++ S+ ++I + ++K I I+L V+ L ++ + +N + D L P I LT L L+L + NKK G+ +SG+L+ FW +L I + + S++ ++ S+ + + Y IY+PLVV + L F D P Y E +V P PE ASFPS++ FGW ++L G++ PL +++ +NPN + K W K KV + + + + D ++ L + FG F+ GV++ V + PQ + LLI F+ S DEPLW+GYLY LL +I+TL+ QYF L++G +RT LI+AIYRK ++S S+R++ +VGE VNLMS+D +R V +N +W APL I+L+LYFLWG LGPS L+GL +MIILIP+NA L+ +++ Q MK KD R++ MNEVL GIKV+KLYAWEPSF+E+I IR+ E++ LK+ +Y+ A +FI++ A F+V+LV+F T+V +D NVLD+E AFVS+S FN++R PL+ P + ++QASVS KR+++F+N+ E D + +E + + + + NG+FAWD + + INL+I++G LVAIVG VG+GKSSLISA+LG+MEK +G VN G +AYV QQAWIQN T++ NILFG +Y V ACAL DF +L GDQTEIGEKGINLSGGQKQRVSLARAVYNN DIY LDDP+SAVD+HVGKHIFE++I SR G++K KTR+LVTH +T+L E D I+V+K+G ISE GT+ +L+ G F+ FL ++ + D S E + + L+ + + EL + + A + + S S+ +K + RK S S N+ + KL+ EK ET +V VY +Y ++IG F+ ++ + AV Q+FS+ N+WL+ WS D ++ + ++MYLG YG G A+ V + L + +G L S +LHN LL IL +P+ FFDT P GRILNRFGKDVD +D +P N + L + T+VVI + P+FI V +P+ L Y+FIQ+ Y+ TSRQLKRL S++RSPIYS FGE+++G I+A+ +QD+ + +ES+VD Q Y + ANRWL+VRLEM+GN++I F+ALFAVL +D + G VGLS+SYA QIT L +L+RM S +E N+V+VERI+EY + QEAP+ P + K WP RG++ F DYK RYR GLDLVL G++ + GEKIGIVGRTGAGKSSLT+ALFR+IE + G I ID DI+ LGL LRS +TIIPQDPVLFSG++RLNLDPF +DD IWRAL+ HL ++V GL L E++EGG NLSVGQRQL+CLARALLRKT++L+LDEATAAVDLE DDLIQ TIR+EFKDCT+LTIAHRLNTI+D DRVIVL G I E D P LLQ +S F+ MAK+AGL
Sbjct: 8 QFCGSKFWDANLSWYTDNPDLTECFQKTVLIWVPCIFLWICSSFEAYYLVNSKRKNIPLTWLFISKYIITVALILLTVLDLGKTIRNWVLDNIVYDV--DFLTPCIKILTFILCLVLLIYNKKYGMRTSGLLWMFWCLLAICGIVQYRSLLT----KSYNEIGSLYEYVSYNIYYPLVVMMFLLNFLVDAEPKYSEYP-RVKTPCPEQSASFPSRLTFGWFNSLAWKGFKNPLQTSDLWSMNPNDMAKEIVPLFDKHWNKSLSKVDNSQGANAVFSKSSGRVDFSSGKKKKTASVLPPLCKAFGPIFM-------FGVMLKVVQDIMTFLSPQILKLLIQFTKSKDEPLWKGYLYAVLLFFTAIIQTLVLAQYFHRMLLVGLRMRTALIAAIYRKALRMSNSARKESTVGEIVNLMSVDAQRFMDVTTYINMIWSAPLQIILALYFLWGILGPSVLSGLAVMIILIPVNALLAGKVRNLQIKQMKNKDDRVKLMNEVLSGIKVLKLYAWEPSFEEQILKIRNKEIKVLKQAAYISAGTSFIWSCAPFMVSLVSFATFVLIDEKNVLDSETAFVSLSLFNILRFPLSMLPMMVSYVVQASVSVKRINKFMNSEELDPNNVQHETSEVNPIVIENGNFAWDSEHIEKPMLRNINLQIKQGQLVAIVGSVGSGKSSLISAMLGEMEKLSGKVNTKGKIAYVSQQAWIQNATLQDNILFGSPFNKALYHRVVEACALTPDFKMLPAGDQTEIGEKGINLSGGQKQRVSLARAVYNNADIYFLDDPLSAVDSHVGKHIFENLIGSR-GLIKKKTRILVTHGITYLPEVDHIIVLKDGEISESGTYKELLDKRGSFADFLVQHLQEVKPDEESSEDLMEIKQKLE--NTIGSEELQQKISQARTRASVSI-----SDSTSIADKKSLNGSLHRKPSTDSQQSGSLVQSNNVKEINQNQYKTGEKLIETEKAETGSVKWTVYSHYLQSIGWFLAVSTIIMNAVFQSFSISANLWLSAWSSDNETVVNGTANTYKQNMYLGVYGAFGLGQAIFVCLAQLAMVVGCLRCSHQLHNGLLLGILRSPIGFFDTTPSGRILNRFGKDVDIIDDVLPPNIKAWLFCLCSVIATLVVISYSTPMFISVIVPIGLVYYFIQRFYVATSRQLKRLESVSRSPIYSHFGESVTGAQIIRAYGVQDRFVNESESRVDFNQVCYYPSIIANRWLAVRLEMVGNLIIFFSALFAVLDKDTMSAGLVGLSISYALQITQTLNWLVRMTSDVETNIVAVERIKEYSE-TSQEAPWEIPDQDP-PKDWPMRGSVEFHDYKVRYRDGLDLVLNGLSFSVDGGEKIGIVGRTGAGKSSLTLALFRIIEAAYGKIVIDEVDISKLGLHTLRSRLTIIPQDPVLFSGSLRLNLDPFNKCSDDDIWRALEHAHLKDFVKGLPNTLTHEVTEGGDNLSVGQRQLMCLARALLRKTKVLILDEATAAVDLETDDLIQRTIREEFKDCTVLTIAHRLNTILDSDRVIVLDKGSIIEFDSPDNLLQKQDSAFYSMAKDAGL 1532
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. nr
Match: gi|1133439954|ref|XP_019876350.1| (PREDICTED: LOW QUALITY PROTEIN: multidrug resistance-associated protein 1-like [Aethina tumida]) HSP 1 Score: 1389.4 bits (3595), Expect = 0.000e+0 Identity = 728/1547 (47.06%), Postives = 994/1547 (64.25%), Query Frame = 0
Query: 23 GGLMKFCHDPFWDLNTTWFTLDPDFTHCFHQTALVYVPCGLLWLLAPLEIYWINASQSRHIRWNLINVAKCISIALCIILDVISLSLSLGYFGNNTSWLSLSDILAPLIVFLTHALALILTLMNKKMGLTSSGILFTFWFVLVITSGLTFASVVRFGAFRTITSSWSVEQSMIYTIYFPLVVAISFLTFWADPPPVYWEVEDQVDVPSPEMYASFPSKIAFGWIDTLIKMGWQTPLNQRNIFDLNPNLTTN----ILTKKWAKHEKKVRHP----MRGTLKTD----------------LIQTLARCFGVDFLIASGLQILGVLINQVFFVCCKAVPQTISLLITFSTSDEPLWRGYLYMSLLVAINMIRTLLNTQYFFIYLVLGQNVRTTLISAIYRKTFKLSASSRRQRSVGETVNLMSIDTERMNIVVGSLNNLWYAPLVILLSLYFLWGYLGPSCLAGLGMMIILIPINAWLSSRIKKYQFANMKKKDQRLETMNEVLEGIKVMKLYAWEPSFQEKIAAIRDSEVETLKKISYLGALQTFIFNSAVFLVTLVTFGTYVYLDPSNVLDAEKAFVSISYFNLMRGPLNQFPQFIIQLIQASVSHKRLDEFLNAPETDSKIIGNEPNSQHAVEVFNGSFAWDDTEDSSTIHGINLKIERGSLVAIVGQVGAGKSSLISAILGDMEKRTGSVNVDGTVAYVPQQAWIQNDTVRQNILFGRDHFPNIYFETVRACALVEDFTILEQGDQTEIGEKGINLSGGQKQRVSLARAVYNNRDIYLLDDPMSAVDAHVGKHIFEHVISSRTGVLKDKTRLLVTHNVTFLHETDLILVMKNGRISEMGTFNDLMSGGGDFSLFLAEYGNISEQDAGSVEQVETFQDTLDMVSNLSQNELNKTPPDPSSPAFLDLNSPLGSTIGSVKI-----RKRNSAKTFRKRKGKVGPSSSNKTNSREKGKLVVEEKLETSAVSNAVYVYYAKAIGLFVTITIFGLYAVNQAFSVGTNVWLAKWSDDPQSAI----PKYRDMYLGGYGGLGGASALTVMVVYLIITIGGLNASTKLHNNLLAKILAAPMS-FFDTNPKGRILNRFGKDVDAVDTNVPSNFNSICRLLFNTFGTIVVICATNPLFIVVFIPLFLAYWFIQKLYITTSRQLKRLNSIARSPIYSLFGETLSGVPTIKAFNLQDQLIKINESKVDTLQTTTYLNQAANRWLSVRLEMLGNVVILFAALFAVLGRDKVDPGEVGLSLSYATQITTFLTFLIRMMSMIENNMVSVERIQEYEDHVDQEAPYVCPMESTLEKQWPPRGAIRFQDYKTRYRPGLDLVLKGITCDIHAGEKIGIVGRTGAGKSSLTMALFRLIEPSSGTIYIDGTDITTLGLGFLRSNITIIPQDPVLFSGTMRLNLDPFEIATDDQIWRALKLGHLSEYVSGLRYGLDQEISEGGGNLSVGQRQLVCLARALLRKTQILVLDEATAAVDLEMDDLIQTTIRQEFKDCTILTIAHRLNTIMDCDRVIVLRSGLIAEMDEPQKLLQDTNSIFFGMAKNAGL 1535
G L FC FWD N +W T DPD T CF +T LV+ PC LW + LEIY+I S+ R I WN +NV+K + A +L L S+ + + DI P+I L+ L+ +L + NKK GL +SG+ F FW +L + + F + +R + + + Y IY+PLV+ + L +AD P + + +V+ P PE ASFPS++ F W DTL +G++ PL ++++D+NP + + K W K +K R + K D ++ L FG F + L+++ L+ FV P + LLITF + W+GY+Y LL+A ++T++ +QYF ++G +RT L++ IY+K K+S ++R+Q +VGE VNLM++D ++ + LN +W APL I LS+YFLW LGPS LAGL +MIILIP+N ++++++K Q MK KD+R++ MNE+L GIKV+KLYAWEPSF++++ IR E++ LK+ +Y+ A +FI++ A FLV+LVTF TYV +D SNVLDA KA+VSIS FN++R PL+ P I ++Q VS KR+++FLN E D + ++ N + NG+F+W D + IN+++ +GSL A+VG VG GKSSLI A LG+MEK++G VN G++AYV QQAWIQN T+R NILFG+ IY V+ACAL DF +L GDQTEIGEKGINLSGGQKQRVSLARAVY + +IYLLDDP+SAVD+HVGKHIFE VI TG+L KTR+LVTH +T+L +TD ILVMKNG ISE GT+ +L++ G F+ FL ++ SE A ++++E+ PD F + S + + GS K R+R+ + ++R+ S + +E KL+ EK ET +VS VY YY K+IG F+T L V Q FS+G+NVWL +W+DD A + RDMYLG YG LG + + + L + +G LNA+ LH LL I+ P + F+D P GRILNRF KDVD +D +P F+ GT+VVI T PLFI+V IP+ L Y+FIQ+ Y+ TSRQLKRL S++RSPIYS FGE+++G I+AF +++ I +E KVD Q Y + +NRWL+VRLEM+GN++I FAALF VLG+D + PG VGLS++YA QIT L +L+RM S +E N+V+VERI+EY + QEA + P ++ WP GA+ F++Y RYRPGLDLVLKG+ ++ GEKIGIVGRTGAGKSSLT+ALFR+IE G IYIDG I+ LGL LRS +TIIPQD VLFSG++R+NLDPF+ +DD++WR+L+ HL ++V GL G+ +++EGG NLSVGQRQL+CLARALLRKT++LVLDEATAAVDLE DDLIQ TIR EFK+CT+LTIAHRLNTIMD DRV+VL G I E D P LL ++ SIF+ M K+AGL
Sbjct: 4 GTLDLFCGSDFWDYNLSWNTTDPDLTKCFERTVLVWFPCAFLWTFSILEIYYITNSKKRDIPWNWLNVSKLVVTAALCVLSATDLVTSVKNAKSEDGSVPKVDIYTPVIKILSFLLSAVLLVFNKKHGLQTSGLQFLFWLLLGLCGAVQFRTEIRQAQVQVPEPYYDY---VSYLIYYPLVLIMLLLNCFADKSPKHTQYA-KVERPCPEEGASFPSRLLFAWFDTLAWLGFKKPLEAQDLWDMNPQDSAKEVVPLFEKYWHKTLQKCESSSSPHTRASFKPDSASVDFVNSSKKKPASILPALVESFGPTFFFGASLKLVQDLLT---FVS----PIILGLLITFVKEQQETWKGYMYAVLLLATATVQTIILSQYFNRMFIVGMRIRTALVATIYKKALKISNAARKQTTVGEIVNLMAVDAQKFVDLTAYLNMIWSAPLQIFLSMYFLWNELGPSVLAGLAIMIILIPVNGFIANKVKVLQIKQMKNKDERVKLMNEILSGIKVLKLYAWEPSFEKQVLQIRAKEIKVLKEAAYMNAGTSFIWSCAPFLVSLVTFATYVLVDESNVLDANKAYVSISLFNILRFPLSMLPMMISNMVQTWVSVKRINKFLNEEELDPNNVTHDQNEVDPIIFENGNFSWGD---EPVLKNINIRLTKGSLNAVVGTVGCGKSSLIYASLGEMEKKSGRVNTVGSIAYVSQQAWIQNATLRDNILFGKKFDQKIYDNVVKACALKPDFDMLPAGDQTEIGEKGINLSGGQKQRVSLARAVYADAEIYLLDDPLSAVDSHVGKHIFEQVIGP-TGLLGKKTRVLVTHGITYLPQTDKILVMKNGEISESGTYQELLNKKGSFAEFLLQHA--SEGPAEDLDEIES------------------QVPDEIKTEFKRMRSHVSESEGSEKANGSLQRQRSIDSSGKERQRSKSIEDSKSVSKKEGEKLIEAEKSETGSVSWQVYKYYLKSIGFFLTAATILLNMVFQGFSIGSNVWLGRWADDKDLANGTQNTQKRDMYLGVYGALGIGQVIAIFLSVLALYVGTLNAAKSLHRLLLENIMKVPTTTFYDVTPVGRILNRFSKDVDTLDNVLPMTLRGWITCFFSVIGTLVVISYTTPLFIIVIIPIGLLYYFIQRFYVATSRQLKRLESVSRSPIYSHFGESITGAQAIRAFGQEERFITESERKVDQNQVCYYPSIISNRWLAVRLEMIGNLIIFFAALFGVLGKDNL-PGLVGLSVTYALQITQTLNWLVRMTSDVETNIVAVERIKEYGE-ATQEAAWEVPSKNP-SSLWPEVGAVEFKNYAVRYRPGLDLVLKGVDFSVNGGEKIGIVGRTGAGKSSLTLALFRIIEAVQGDIYIDGVKISELGLHTLRSRLTIIPQDAVLFSGSLRMNLDPFDKHSDDEVWRSLEHAHLKDFVKGLPSGIQHQVTEGGENLSVGQRQLICLARALLRKTKVLVLDEATAAVDLETDDLIQRTIRTEFKNCTVLTIAHRLNTIMDSDRVLVLDKGQIVEFDSPATLLLNSKSIFYSMCKDAGL 1512
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. nr
Match: gi|936688206|ref|XP_014222082.1| (multidrug resistance-associated protein 1 isoform X9 [Trichogramma pretiosum]) HSP 1 Score: 1386.7 bits (3588), Expect = 0.000e+0 Identity = 734/1557 (47.14%), Postives = 1015/1557 (65.19%), Query Frame = 0
Query: 28 FCHDPFWDLNTTWFTLDPDFTHCFHQTALVYVPCGLLWLLAPLEIYWINASQSRHIRWNLINVAKCISIALCIILDVISLSLSLGYFGNNTSWLSLSDILAPLIVFLTHALALILTLMNKKMGLTSSGILFTFWFVLVITSGLTFASVVRFGAFRTITSSWSVEQSMIYTIYFPLVVAISFLTFWADPPPVYWEVEDQVDVPSPEMYASFPSKIAFGWIDTLIKMGWQTPLNQRNIFDLNP-NLTTNIL---TKKWAKHEKKVRHPMRGTLKT-------------------DLIQTLARCFGVDFLIASGLQILGVLINQVFFVCCKAVPQTISLLITF-STSDEPLWRGYLYMSLLVAINMIRTLLNTQYFFIYLVLGQNVRTTLISAIYRKTFKLSASSRRQRSVGETVNLMSIDTERMNIVVGSLNNLWYAPLVILLSLYFLWGYLGPSCLAGLGMMIILIPINAWLSSRIKKYQFANMKKKDQRLETMNEVLEGIKVMKLYAWEPSFQEKIAAIRDSEVETLKKISYLGALQTFIFNSAVFLVTLVTFGTYVYLDPSNVLDAEKAFVSISYFNLMRGPLNQFPQFIIQLIQASVSHKRLDEFLNAPETDSKIIGNEPNSQHAVEVFNGSFAWDD--TEDSSTIHGINLKIERGSLVAIVGQVGAGKSSLISAILGDMEKRTGSVNVDGTVAYVPQQAWIQNDTVRQNILFGRDHFPNIYFETVRACALVEDFTILEQGDQTEIGEKGINLSGGQKQRVSLARAVYNNRDIYLLDDPMSAVDAHVGKHIFEHVISSRTGVLKDKTRLLVTHNVTFLHETDLILVMKNGRISEMGTFNDLMSGGGDFSLFLAEYGNISEQDAGSVEQVETFQDTLDMVSNLSQNELNKTPPDPSSPAFLDLNSPLGSTIGSVKIRKRNSAKTFRK----RKGKVGPSSSNKTNSREK------GKLVVEEKLETSAVSNAVYVYYAKAIGLFVTITIFGLYAVNQAFSVGTNVWLAKWSDDPQS------------AIPKYRDMYLGGYGGLGGASALTVMVVYLIITIGGLNASTKLHNNLLAKILAAPMSFFDTNPKGRILNRFGKDVDAVDTNVPSNFNSICRLLFNTFGTIVVICATNPLFIVVFIPLFLAYWFIQKLYITTSRQLKRLNSIARSPIYSLFGETLSGVPTIKAFNLQDQLIKINESKVDTLQTTTYLNQAANRWLSVRLEMLGNVVILFAALFAVLGRDKVDPGEVGLSLSYATQITTFLTFLIRMMSMIENNMVSVERIQEYEDHVDQEAPYVCPMESTLEKQWPPRGAIRFQDYKTRYRPGLDLVLKGITCDIHAGEKIGIVGRTGAGKSSLTMALFRLIEPSSGTIYIDGTDITTLGLGFLRSNITIIPQDPVLFSGTMRLNLDPFEIATDDQIWRALKLGHLSEYVSGLRYGLDQEISEGGGNLSVGQRQLVCLARALLRKTQILVLDEATAAVDLEMDDLIQTTIRQEFKDCTILTIAHRLNTIMDCDRVIVLRSGLIAEMDEPQKLLQDTNSIFFGMAKNAGLM 1536
FC FWD + +W T DPD T CF +TAL++ PC LW+ + E Y++ S +++ + + + K + IIL ++ L ++ N ++ + P I +T +A +L NKK G+ +SG+L+ FWF L + + S++R + + S+ + + Y IYFP+V+ + L F D P+Y + V+ P PE ASFPS++ FGW D+L G++ PL +++ +NP ++ I+ K WA+ +KV + RG T ++ L + FG FL GV++ V V PQ +SLLI F ST D P+W+GY Y LL+ +I+TL+ +QYF ++G +RT LI+AIYRK K+S S+R++ +VGE VNLMS+D +R V +N +W APL I+L+LYFLW LGPS L+GL +MIILIP+NA L+ +++ Q MK KD+R++ MNEVL GIKV+KLYAWEPSF+E+I IR+ E++ LK+ +YL A +FI++ A FLV+LV+F TYV +D S+VLD++KAFVS+S FN++R PL+ P I ++QASVS KR+++F+N+ E D + ++P+ + + + NG+F WD +E T+ INLK+++G LVAIVG VG+GKSSLISA+LG+M+K +G VN G++AYV QQAWIQN T++ NILFG+ +Y + ACAL D +L GDQTEIGEKGINLSGGQKQRVSLARA+YNN DIY LDDP+SAVD+HVGKHIFE++I G++K KTR+LVTH +T+L E D I+V+K+G ISE GT+ +L+ G F+ FL ++ + + E + + L+ + + EL + S + + S GS+ R+ + R+ + + P SN ++E+ KL+ EK ET +V VY +Y K+IG F+ I+ + A+ Q FS+G+NVWL+ W+DD P YRDMYLG YG LG A V++ L + G L S LH LL IL +P+ FFDT P GRILNRFGKDVD VD +P N + L T+VVI + P+FI V +P+ L Y+FIQ+ Y+ TSRQLKRL S++RSPIYS FGE+++G TI+A+ +QD+ IK +ES+VD Q Y + ANRWL++RLEM+GN +I FAALFAVL + ++ G VGLS+SYA QIT L +L+RM S +E N+V+VERI+EY + QEA + P E+ +K WP +G++ F D+K RYR GLDLVL G++ ++ GEKIGIVGRTGAGKSSLT+ALFR+IE + G I ID DI+ LGL LRS +TIIPQDPVLFSG++RLNLDPF +D +W+AL+ HL ++V L GL+ E++EGG NLSVGQRQL+CLARALLRKT++LVLDEATAAVDLE DDLIQTTIRQEFK+CT+LTIAHRLNTI+D DRVIVL G I E D P LLQ +S F+ MAK+AGL+
Sbjct: 10 FCGSKFWDFDISWNTDDPDLTSCFQKTALIWAPCFFLWIFSSFEAYYLVNSSKKNVPLSWLFITKTVFTVALIILTIMDLGKAIIDIANGLEVYAV-EYTTPCIKIITFVIAEVLMFYNKKYGMRTSGLLWMFWFFLSLCGIVQCRSLLR----KDSSEIESMYEFVSYMIYFPIVILLFLLNFLVDSEPLYSKYP-AVEKPCPEQSASFPSRLTFGWFDSLAWKGFKHPLQTSDLWSMNPVDMAKEIVPRFDKYWAESLQKVDN-TRGAKATFRKSSGQVDFNNGKKKKMASVLPPLCKAFGPIFL-------FGVMLKVVQDVMTFISPQILSLLIDFTSTKDVPVWKGYFYAILLLLTAVIQTLVLSQYFHRMFLVGLRMRTALIAAIYRKALKMSNSARKESTVGEIVNLMSVDAQRFMDVTAYINMIWSAPLQIVLALYFLWNSLGPSVLSGLAVMIILIPVNALLAGKVRNLQIKQMKNKDERVKLMNEVLNGIKVLKLYAWEPSFEEQILQIRNKEIKVLKEAAYLNAGTSFIWSCAPFLVSLVSFATYVLVDESHVLDSKKAFVSLSLFNILRFPLSMLPMMISNVVQASVSVKRINKFMNSEELDPNNVQHDPSEANPLVIENGNFTWDSESSESKPTLQNINLKVKQGQLVAIVGTVGSGKSSLISALLGEMDKISGRVNTKGSIAYVSQQAWIQNATLQDNILFGKPLDKALYHRVIEACALSPDLKMLPAGDQTEIGEKGINLSGGQKQRVSLARAIYNNSDIYFLDDPLSAVDSHVGKHIFENLIGPH-GLMKKKTRILVTHGITYLPEVDNIVVLKDGEISESGTYKELLEKRGAFADFLVQHLQEVKSEEEDTEDLLEIKQKLE--TTIGSEELQQRINQARSRTSVSV-----SESGSLADRRSLNGSLHRQPSTDSQQSLSPLRSNSVKNKEEVQYKVGEKLIETEKAETGSVKWKVYSHYLKSIGWFLAISTIIMNAIFQGFSIGSNVWLSVWADDHHYINKTIEGVMMNVTDPSYRDMYLGVYGALGLGQATFVLLAQLTMVSGCLRCSYLLHYKLLFGILHSPIGFFDTTPSGRILNRFGKDVDIVDNVLPPNIRAWLFCLVTVIATLVVISYSTPIFIAVILPIGLIYYFIQRFYVATSRQLKRLESVSRSPIYSHFGESVTGAQTIRAYGVQDRFIKESESRVDFNQVCYYPSIIANRWLAIRLEMVGNFIIFFAALFAVLDKQEMSSGLVGLSISYALQITQTLNWLVRMTSDVETNIVAVERIKEYGE-TPQEAAWNKP-ENDPDKDWPVQGSVEFHDFKVRYREGLDLVLSGLSFKVNGGEKIGIVGRTGAGKSSLTLALFRIIEAADGKILIDNVDISNLGLHTLRSRLTIIPQDPVLFSGSLRLNLDPFNKCSDTDLWKALEHAHLKDFVKSLPNGLNHEVTEGGDNLSVGQRQLICLARALLRKTKVLVLDEATAAVDLETDDLIQTTIRQEFKECTVLTIAHRLNTILDSDRVIVLDKGSIVEYDSPNTLLQKPDSSFYSMAKDAGLV 1542
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. nr
Match: gi|1317163422|ref|XP_023245524.1| (multidrug resistance-associated protein 1 isoform X4 [Copidosoma floridanum]) HSP 1 Score: 1385.16 bits (3584), Expect = 0.000e+0 Identity = 727/1549 (46.93%), Postives = 1001/1549 (64.62%), Query Frame = 0
Query: 27 KFCHDPFWDLNTTWFTLDPDFTHCFHQTALVYVPCGLLWLLAPLEIYWINASQSRHIRWNLINVAKCISIALCIILDVISLSLSL-GYFGNNTSWLSLSDILAPLIVFLTHALALILTLMNKKMGLTSSGILFTFWFVLVITSGLTFASVVRFGAFRTITSSWSVEQSMIYTIYFPLVVAISFLTFWADPPPVYWEVEDQVDVPSPEMYASFPSKIAFGWIDTLIKMGWQTPLNQRNIFDLNPNLTTN----ILTKKWAKHEKKVRHPM-------RGTLKTD-----------LIQTLARCFGVDFLIASGLQILGVLINQVFFVCCKAVPQTISLLITFSTS-DEPLWRGYLYMSLLVAINMIRTLLNTQYFFIYLVLGQNVRTTLISAIYRKTFKLSASSRRQRSVGETVNLMSIDTERMNIVVGSLNNLWYAPLVILLSLYFLWGYLGPSCLAGLGMMIILIPINAWLSSRIKKYQFANMKKKDQRLETMNEVLEGIKVMKLYAWEPSFQEKIAAIRDSEVETLKKISYLGALQTFIFNSAVFLVTLVTFGTYVYLDPSNVLDAEKAFVSISYFNLMRGPLNQFPQFIIQLIQASVSHKRLDEFLNAPETDSKIIGNEPNSQHAVEVFNGSFAWDDTE-DSSTIHGINLKIERGSLVAIVGQVGAGKSSLISAILGDMEKRTGSVNVDGTVAYVPQQAWIQNDTVRQNILFGRDHFPNIYFETVRACALVEDFTILEQGDQTEIGEKGINLSGGQKQRVSLARAVYNNRDIYLLDDPMSAVDAHVGKHIFEHVISSRTGVLKDKTRLLVTHNVTFLHETDLILVMKNGRISEMGTFNDLMSGGGDFSLFLAEY----GNISEQDAGSVEQVETFQD------TLDMVSNLSQNELNKTPPDPSSPAFLDLNSPLGSTIGSVKIRKRNSAKTFRKRKGKVGPSSSNKTNSREKGKLVVEEKLETSAVSNAVYVYYAKAIGLFVTITIFGLYAVNQAFSVGTNVWLAKWSDDPQSAI-----PKYRDMYLGGYGGLGGASALTVMVVYLIITIGGLNASTKLHNNLLAKILAAPMSFFDTNPKGRILNRFGKDVDAVDTNVPSNFNSICRLLFNTFGTIVVICATNPLFIVVFIPLFLAYWFIQKLYITTSRQLKRLNSIARSPIYSLFGETLSGVPTIKAFNLQDQLIKINESKVDTLQTTTYLNQAANRWLSVRLEMLGNVVILFAALFAVLGRDKVDPGEVGLSLSYATQITTFLTFLIRMMSMIENNMVSVERIQEYEDHVDQEAPYVCPMESTLEKQWPPRGAIRFQDYKTRYRPGLDLVLKGITCDIHAGEKIGIVGRTGAGKSSLTMALFRLIEPSSGTIYIDGTDITTLGLGFLRSNITIIPQDPVLFSGTMRLNLDPFEIATDDQIWRALKLGHLSEYVSGLRYGLDQEISEGGGNLSVGQRQLVCLARALLRKTQILVLDEATAAVDLEMDDLIQTTIRQEFKDCTILTIAHRLNTIMDCDRVIVLRSGLIAEMDEPQKLLQDTNSIFFGMAKNAGL 1535
+FC FWD N +W+T +PD T CF +T L++VPC LW+ + E Y++ S+ ++I + ++K I I+L V+ L ++ + +N + D L P I LT L L+L + NKK G+ +SG+L+ FW +L I + + S++ ++ S+ + + Y IY+PLVV + L F D P Y E +V P PE ASFPS++ FGW ++L G++ PL +++ +NPN + K W K KV + + + + D ++ L + FG F+ GV++ V + PQ + LLI F+ S DEPLW+GYLY LL +I+TL+ QYF L++G +RT LI+AIYRK ++S S+R++ +VGE VNLMS+D +R V +N +W APL I+L+LYFLWG LGPS L+GL +MIILIP+NA L+ +++ Q MK KD R++ MNEVL GIKV+KLYAWEPSF+E+I IR+ E++ LK+ +Y+ A +FI++ A F+V+LV+F T+V +D NVLD+E AFVS+S FN++R PL+ P + ++QASVS KR+++F+N+ E D + +E + + + + NG+FAWD + + INL+I++G LVAIVG VG+GKSSLISA+LG+MEK +G VN G +AYV QQAWIQN T++ NILFG +Y V ACAL DF +L GDQTEIGEKGINLSGGQKQRVSLARAVYNN DIY LDDP+SAVD+HVGKHIFE++I SR G++K KTR+LVTH +T+L E D I+V+K+G ISE GT+ +L+ G F+ FL ++ GN+ + S + +E Q + ++ +SQ + S + D S GS + S + K N+ + KL+ EK ET +V VY +Y ++IG F+ ++ + AV Q+FS+ N+WL+ WS D ++ + ++MYLG YG G L+ +V + + IG + AS L+ +L P+SFFDT P GRILNR GKD+D VD +P F+ T+VVI + P+FI V +P+ L Y+FIQ+ Y+ TSRQLKRL S++RSPIYS FGE+++G I+A+ +QD+ + +ES+VD Q Y + ANRWL+VRLEM+GN++I F+ALFAVL +D + G VGLS+SYA QIT L +L+RM S +E N+V+VERI+EY + QEAP+ P + K WP RG++ F DYK RYR GLDLVL G++ + GEKIGIVGRTGAGKSSLT+ALFR+IE + G I ID DI+ LGL LRS +TIIPQDPVLFSG++RLNLDPF +DD IWRAL+ HL ++V GL L E++EGG NLSVGQRQL+CLARALLRKT++L+LDEATAAVDLE DDLIQ TIR+EFKDCT+LTIAHRLNTI+D DRVIVL G I E D P LLQ +S F+ MAK+AGL
Sbjct: 8 QFCGSKFWDANLSWYTDNPDLTECFQKTVLIWVPCIFLWICSSFEAYYLVNSKRKNIPLTWLFISKYIITVALILLTVLDLGKTIRNWVLDNIVYDV--DFLTPCIKILTFILCLVLLIYNKKYGMRTSGLLWMFWCLLAICGIVQYRSLLT----KSYNEIGSLYEYVSYNIYYPLVVMMFLLNFLVDAEPKYSEYP-RVKTPCPEQSASFPSRLTFGWFNSLAWKGFKNPLQTSDLWSMNPNDMAKEIVPLFDKHWNKSLSKVDNSQGANAVFSKSSGRVDFSSGKKKKTASVLPPLCKAFGPIFM-------FGVMLKVVQDIMTFLSPQILKLLIQFTKSKDEPLWKGYLYAVLLFFTAIIQTLVLAQYFHRMLLVGLRMRTALIAAIYRKALRMSNSARKESTVGEIVNLMSVDAQRFMDVTTYINMIWSAPLQIILALYFLWGILGPSVLSGLAVMIILIPVNALLAGKVRNLQIKQMKNKDDRVKLMNEVLSGIKVLKLYAWEPSFEEQILKIRNKEIKVLKQAAYISAGTSFIWSCAPFMVSLVSFATFVLIDEKNVLDSETAFVSLSLFNILRFPLSMLPMMVSYVVQASVSVKRINKFMNSEELDPNNVQHETSEVNPIVIENGNFAWDSEHIEKPMLRNINLQIKQGQLVAIVGSVGSGKSSLISAMLGEMEKLSGKVNTKGKIAYVSQQAWIQNATLQDNILFGSPFNKALYHRVVEACALTPDFKMLPAGDQTEIGEKGINLSGGQKQRVSLARAVYNNADIYFLDDPLSAVDSHVGKHIFENLIGSR-GLIKKKTRILVTHGITYLPEVDHIIVLKDGEISESGTYKELLDKRGSFADFLVQHLQEVGNLKPDEESSEDLMEIKQKLENTIGSEELQQKISQARTRASVSISDSTSIADKKSLNGSLHRKPSTDSQQSGSLVQSNNVK----EINQNQYKTGEKLIETEKAETGSVKWTVYSHYLQSIGWFLAVSTIIMNAVFQSFSISANLWLSAWSSDNETVVNGTANTYKQNMYLGVYGAFGLGQGLSNFLVSIFLAIGSIIASKSTFEQLIGNVLRNPISFFDTTPNGRILNRLGKDIDTVDNVLPGILRMWVTCFFSVIATLVVISYSTPMFISVIVPIGLVYYFIQRFYVATSRQLKRLESVSRSPIYSHFGESVTGAQIIRAYGVQDRFVNESESRVDFNQVCYYPSIIANRWLAVRLEMVGNLIIFFSALFAVLDKDTMSAGLVGLSISYALQITQTLNWLVRMTSDVETNIVAVERIKEYSE-TSQEAPWEIP-DQDPPKDWPMRGSVEFHDYKVRYRDGLDLVLNGLSFSVDGGEKIGIVGRTGAGKSSLTLALFRIIEAAYGKIVIDEVDISKLGLHTLRSRLTIIPQDPVLFSGSLRLNLDPFNKCSDDDIWRALEHAHLKDFVKGLPNTLTHEVTEGGDNLSVGQRQLMCLARALLRKTKVLILDEATAAVDLETDDLIQRTIREEFKDCTVLTIAHRLNTILDSDRVIVLDKGSIIEFDSPDNLLQKQDSAFYSMAKDAGL 1535 HSP 2 Score: 95.9005 bits (237), Expect = 7.060e-16 Identity = 114/453 (25.17%), Postives = 200/453 (44.15%), Query Frame = 0
Query: 1156 LFGETLSGVPTIKAF----NLQDQLIKINESKVDTLQTTTYLNQAANRWLSVRLEMLGNVVILFAALFAVLGRDKVDPGEVGLSLSYATQITTFLTFLIRMMSMIENNMVSVERIQEYEDHVDQEAPYVCPMESTLEKQWPPRGAIRFQDYKTRYRPGLDLVLKGITCDIHAGEKIGIVGRTGAGKSSLTMALFRLIEPSSGTIYIDGTDITTLGLGFLRSNITIIPQDPVLFSGTMRLNLDPFEIATDDQIWRALKLGHLSEYVSGLRYGLDQEISEGGGNLSVGQRQLVCLARALLRKTQILVLDEATAAVDLEMDDLIQTTI---RQEFKDCTILTIAHRLNTIMDCDRVIVLRSGLIAEMDEPQKLLQDTNSIFFGMAKN----AGLMSEQEAK------RQRVSDLLDAELDPKRISEI-----VGVSERTVRNIRAAKKIGNGVERK 1586
L E LSG+ +K + + ++Q++KI ++ L+ Y++ + S M+ ++ FA + ++ +D +SLS + L+ L M+S + VSV+RI ++ + + + V S + G + D + +P +L+ I I G+ + IVG G+GKSSL A+ +E SG + G I + N T+ QD +LF PF A R ++ L+ L G EI E G NLS GQ+Q V LARA+ I LD+ +AVD + I + R K T + + H + + + D +IVL+ G I+E ++LL S + ++ L ++E+ +Q++ + + +E ++IS+ V +S+ T +I K + + RK
Sbjct: 486 LMNEVLSGIKVLKLYAWEPSFEEQILKIRNKEIKVLKQAAYISAGTSFIWSCAPFMVS--LVSFATFVLIDEKNVLDSETAFVSLSLFNILRFPLSMLPMMVSYVVQASVSVKRINKFMNSEELDPNNVQHETSEVNPIVIENGNFAW-DSEHIEKP----MLRNINLQIKQGQLVAIVGSVGSGKSSLISAMLGEMEKLSGKVNTKG-KIAYVSQQAWIQNATL--QDNILFGS-------PFNKALYH---RVVEACALTPDFKMLPAGDQTEIGEKGINLSGGQKQRVSLARAVYNNADIYFLDDPLSAVDSHVGKHIFENLIGSRGLIKKKTRILVTHGITYLPEVDHIIVLKDGEISESGTYKELLDKRGSFADFLVQHLQEVGNLKPDEESSEDLMEIKQKLENTIGSEELQQKISQARTRASVSISDST--SIADKKSLNGSLHRK 916
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. nr
Match: gi|936688198|ref|XP_014222079.1| (multidrug resistance-associated protein 1 isoform X4 [Trichogramma pretiosum]) HSP 1 Score: 1383.62 bits (3580), Expect = 0.000e+0 Identity = 736/1572 (46.82%), Postives = 1021/1572 (64.95%), Query Frame = 0
Query: 28 FCHDPFWDLNTTWFTLDPDFTHCFHQTALVYVPCGLLWLLAPLEIYWINASQSRHIRWNLINVAKCISIALCIILDVISLSLSLGYFGNNTSWLSLSDILAPLIVFLTHALALILTLMNKKMGLTSSGILFTFWFVLVITSGLTFASVVRFGAFRTITSSWSVEQSMIYTIYFPLVVAISFLTFWADPPPVYWEVEDQVDVPSPEMYASFPSKIAFGWIDTLIKMGWQTPLNQRNIFDLNP-NLTTNIL---TKKWAKHEKKV-RH--------PMRGTLKT-------------------DLIQTLARCFGVDFLIASGLQILGVLINQVFFVCCKAVPQTISLLITF-STSDEPLWRGYLYMSLLVAINMIRTLLNTQYFFIYLVLGQNVRTTLISAIYRKTFKLSASSRRQRSVGETVNLMSIDTERMNIVVGSLNNLWYAPLVILLSLYFLWGYLGPSCLAGLGMMIILIPINAWLSSRIKKYQFANMKKKDQRLETMNEVLEGIKVMKLYAWEPSFQEKIAAIRDSEVETLKKISYLGALQTFIFNSAVFLVTLVTFGTYVYLDPSNVLDAEKAFVSISYFNLMRGPLNQFPQFIIQLIQASVSHKRLDEFLNAPETDSKIIGNEPNSQHAVEVFNGSFAWDD--TEDSSTIHGINLKIERGSLVAIVGQVGAGKSSLISAILGDMEKRTGSVNVDGTVAYVPQQAWIQNDTVRQNILFGRDHFPNIYFETVRACALVEDFTILEQGDQTEIGEKGINLSGGQKQRVSLARAVYNNRDIYLLDDPMSAVDAHVGKHIFEHVISSRTGVLKDKTRLLVTHNVTFLHETDLILVMKNGRISEMGTFNDLMSGGGDFSLFLAEY----GNISEQDAGSV------EQVETFQDTLDMVSNLSQNELNKTPPDPSSPAFLDLNSPLGSTIGSVKIRKRNSAKTFRKRKGKVGPSSSNKTNSREK------GKLVVEEKLETSAVSNAVYVYYAKAIGLFVTITIFGLYAVNQAFSVGTNVWLAKWSDDPQS------------AIPKYRDMYLGGYGGLGGASALTVMVVYLIITIGGLNASTKLHNNLLAKILAAPMSFFDTNPKGRILNRFGKDVDAVDTNVPSNFNSICRLLFNTFGTIVVICATNPLFIVVFIPLFLAYWFIQKLYITTSRQLKRLNSIARSPIYSLFGETLSGVPTIKAFNLQDQLIKINESKVDTLQTTTYLNQAANRWLSVRLEMLGNVVILFAALFAVLGRDKVDPGEVGLSLSYATQITTFLTFLIRMMSMIENNMVSVERIQEYEDHVDQEAPYVCPMESTLEKQWPPRGAIRFQDYKTRYRPGLDLVLKGITCDIHAGEKIGIVGRTGAGKSSLTMALFRLIEPSSGTIYIDGTDITTLGLGFLRSNITIIPQDPVLFSGTMRLNLDPFEIATDDQIWRALKLGHLSEYVSGLRYGLDQEISEGGGNLSVGQRQLVCLARALLRKTQILVLDEATAAVDLEMDDLIQTTIRQEFKDCTILTIAHRLNTIMDCDRVIVLRSGLIAEMDEPQKLLQDTNSIFFGMAKNAGLM 1536
FC FWD + +W T DPD T CF +TAL++ PC LW+ + E Y++ S +++ + + + K + IIL ++ L ++ N ++ + P I +T +A +L NKK G+ +SG+L+ FWF L + + S++R + + S+ + + Y IYFP+V+ + L F D P+Y + V+ P PE ASFPS++ FGW D+L G++ PL +++ +NP ++ I+ K WA+ +KV +H RG T ++ L + FG FL GV++ V V PQ +SLLI F ST D P+W+GY Y LL+ +I+TL+ +QYF ++G +RT LI+AIYRK K+S S+R++ +VGE VNLMS+D +R V +N +W APL I+L+LYFLW LGPS L+GL +MIILIP+NA L+ +++ Q MK KD+R++ MNEVL GIKV+KLYAWEPSF+E+I IR+ E++ LK+ +YL A +FI++ A FLV+LV+F TYV +D S+VLD++KAFVS+S FN++R PL+ P I ++QASVS KR+++F+N+ E D + ++P+ + + + NG+F WD +E T+ INLK+++G LVAIVG VG+GKSSLISA+LG+M+K +G VN G++AYV QQAWIQN T++ NILFG+ +Y + ACAL D +L GDQTEIGEKGINLSGGQKQRVSLARA+YNN DIY LDDP+SAVD+HVGKHIFE++I G++K KTR+LVTH +T+L E D I+V+K+G ISE GT+ +L+ G F+ FL ++ GN+ ++ + +++ET + ++ ++Q + S + D S GS + ++ S + + + P SN ++E+ KL+ EK ET +V VY +Y K+IG F+ I+ + A+ Q FS+G+NVWL+ W+DD P YRDMYLG YG LG A V++ L + G L S LH LL IL +P+ FFDT P GRILNRFGKDVD VD +P N + L T+VVI + P+FI V +P+ L Y+FIQ+ Y+ TSRQLKRL S++RSPIYS FGE+++G TI+A+ +QD+ IK +ES+VD Q Y + ANRWL++RLEM+GN +I FAALFAVL + ++ G VGLS+SYA QIT L +L+RM S +E N+V+VERI+EY + QEA + P E+ +K WP +G++ F D+K RYR GLDLVL G++ ++ GEKIGIVGRTGAGKSSLT+ALFR+IE + G I ID DI+ LGL LRS +TIIPQDPVLFSG++RLNLDPF +D +W+AL+ HL ++V L GL+ E++EGG NLSVGQRQL+CLARALLRKT++LVLDEATAAVDLE DDLIQTTIRQEFK+CT+LTIAHRLNTI+D DRVIVL G I E D P LLQ +S F+ MAK+AGL+
Sbjct: 10 FCGSKFWDFDISWNTDDPDLTSCFQKTALIWAPCFFLWIFSSFEAYYLVNSSKKNVPLSWLFITKTVFTVALIILTIMDLGKAIIDIANGLEVYAV-EYTTPCIKIITFVIAEVLMFYNKKYGMRTSGLLWMFWFFLSLCGIVQCRSLLR----KDSSEIESMYEFVSYMIYFPIVILLFLLNFLVDSEPLYSKYP-AVEKPCPEQSASFPSRLTFGWFDSLAWKGFKHPLQTSDLWSMNPVDMAKEIVPRFDKYWAESLQKVDKHFWTNQNFSSTRGAKATFRKSSGQVDFNNGKKKKMASVLPPLCKAFGPIFL-------FGVMLKVVQDVMTFISPQILSLLIDFTSTKDVPVWKGYFYAILLLLTAVIQTLVLSQYFHRMFLVGLRMRTALIAAIYRKALKMSNSARKESTVGEIVNLMSVDAQRFMDVTAYINMIWSAPLQIVLALYFLWNSLGPSVLSGLAVMIILIPVNALLAGKVRNLQIKQMKNKDERVKLMNEVLNGIKVLKLYAWEPSFEEQILQIRNKEIKVLKEAAYLNAGTSFIWSCAPFLVSLVSFATYVLVDESHVLDSKKAFVSLSLFNILRFPLSMLPMMISNVVQASVSVKRINKFMNSEELDPNNVQHDPSEANPLVIENGNFTWDSESSESKPTLQNINLKVKQGQLVAIVGTVGSGKSSLISALLGEMDKISGRVNTKGSIAYVSQQAWIQNATLQDNILFGKPLDKALYHRVIEACALSPDLKMLPAGDQTEIGEKGINLSGGQKQRVSLARAIYNNSDIYFLDDPLSAVDSHVGKHIFENLIGPH-GLMKKKTRILVTHGITYLPEVDNIVVLKDGEISESGTYKELLEKRGAFADFLVQHLQEVGNLKSEEEDTEDLLEIKQKLETTIGSEELQQRINQARSRTSVSVSESGSLADRRSLNGS------LHRQPSTDS----QQSLSPLRSNSVKNKEEVQYKVGEKLIETEKAETGSVKWKVYSHYLKSIGWFLAISTIIMNAIFQGFSIGSNVWLSVWADDHHYINKTIEGVMMNVTDPSYRDMYLGVYGALGLGQATFVLLAQLTMVSGCLRCSYLLHYKLLFGILHSPIGFFDTTPSGRILNRFGKDVDIVDNVLPPNIRAWLFCLVTVIATLVVISYSTPIFIAVILPIGLIYYFIQRFYVATSRQLKRLESVSRSPIYSHFGESVTGAQTIRAYGVQDRFIKESESRVDFNQVCYYPSIIANRWLAIRLEMVGNFIIFFAALFAVLDKQEMSSGLVGLSISYALQITQTLNWLVRMTSDVETNIVAVERIKEYGE-TPQEAAWNKP-ENDPDKDWPVQGSVEFHDFKVRYREGLDLVLSGLSFKVNGGEKIGIVGRTGAGKSSLTLALFRIIEAADGKILIDNVDISNLGLHTLRSRLTIIPQDPVLFSGSLRLNLDPFNKCSDTDLWKALEHAHLKDFVKSLPNGLNHEVTEGGDNLSVGQRQLICLARALLRKTKVLVLDEATAAVDLETDDLIQTTIRQEFKECTVLTIAHRLNTILDSDRVIVLDKGSIVEYDSPNTLLQKPDSSFYSMAKDAGLV 1555
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. nr
Match: gi|936574288|ref|XP_014219240.1| (multidrug resistance-associated protein 1 isoform X5 [Copidosoma floridanum]) HSP 1 Score: 1382.85 bits (3578), Expect = 0.000e+0 Identity = 725/1549 (46.80%), Postives = 1006/1549 (64.95%), Query Frame = 0
Query: 27 KFCHDPFWDLNTTWFTLDPDFTHCFHQTALVYVPCGLLWLLAPLEIYWINASQSRHIRWNLINVAKCISIALCIILDVISLSLSL-GYFGNNTSWLSLSDILAPLIVFLTHALALILTLMNKKMGLTSSGILFTFWFVLVITSGLTFASVVRFGAFRTITSSWSVEQSMIYTIYFPLVVAISFLTFWADPPPVYWEVEDQVDVPSPEMYASFPSKIAFGWIDTLIKMGWQTPLNQRNIFDLNPNLTTN----ILTKKWAKHEKKVRHPM-------RGTLKTD-----------LIQTLARCFGVDFLIASGLQILGVLINQVFFVCCKAVPQTISLLITFSTS-DEPLWRGYLYMSLLVAINMIRTLLNTQYFFIYLVLGQNVRTTLISAIYRKTFKLSASSRRQRSVGETVNLMSIDTERMNIVVGSLNNLWYAPLVILLSLYFLWGYLGPSCLAGLGMMIILIPINAWLSSRIKKYQFANMKKKDQRLETMNEVLEGIKVMKLYAWEPSFQEKIAAIRDSEVETLKKISYLGALQTFIFNSAVFLVTLVTFGTYVYLDPSNVLDAEKAFVSISYFNLMRGPLNQFPQFIIQLIQASVSHKRLDEFLNAPETDSKIIGNEPNSQHAVEVFNGSFAWDDTE-DSSTIHGINLKIERGSLVAIVGQVGAGKSSLISAILGDMEKRTGSVNVDGTVAYVPQQAWIQNDTVRQNILFGRDHFPNIYFETVRACALVEDFTILEQGDQTEIGEKGINLSGGQKQRVSLARAVYNNRDIYLLDDPMSAVDAHVGKHIFEHVISSRTGVLKDKTRLLVTHNVTFLHETDLILVMKNGRISEMGTFNDLMSGGGDFSLFLAEYGNISEQDAGSVEQVETFQDTLDMVSNLSQNELNKTPPDPSSPAFLDLNSPLGSTIGSVKIRKRNSAKTFRKRKGKVGPSSS----------NKTNSREKGKLVVEEKLETSAVSNAVYVYYAKAIGLFVTITIFGLYAVNQAFSVGTNVWLAKWSDDPQSAI-----PKYRDMYLGGYGGLGGASALTVMVVYLIITIGGLNASTKLHNNLLAKILAAPMSFFDTNPKGRILNRFGKDVDAVDTNVPSNFNSICRLLFNTFGTIVVICATNPLFIVVFIPLFLAYWFIQKLYITTSRQLKRLNSIARSPIYSLFGETLSGVPTIKAFNLQDQLIKINESKVDTLQTTTYLNQAANRWLSVRLEMLGNVVILFAALFAVLGRDKVDPGEVGLSLSYATQITTFLTFLIRMMSMIENNMVSVERIQEYEDHVDQEAPYVCPMESTLEKQWPPRGAIRFQDYKTRYRPGLDLVLKGITCDIHAGEKIGIVGRTGAGKSSLTMALFRLIEPSSGTIYIDGTDITTLGLGFLRSNITIIPQDPVLFSGTMRLNLDPFEIATDDQIWRALKLGHLSEYVSGLRYGLDQEISEGGGNLSVGQRQLVCLARALLRKTQILVLDEATAAVDLEMDDLIQTTIRQEFKDCTILTIAHRLNTIMDCDRVIVLRSGLIAEMDEPQKLLQDTNSIFFGMAKNAGL 1535
+FC FWD N +W+T +PD T CF +T L++VPC LW+ + E Y++ S+ ++I + ++K I I+L V+ L ++ + +N + D L P I LT L L+L + NKK G+ +SG+L+ FW +L I + + S++ ++ S+ + + Y IY+PLVV + L F D P Y E +V P PE ASFPS++ FGW ++L G++ PL +++ +NPN + K W K KV + + + + D ++ L + FG F+ GV++ V + PQ + LLI F+ S DEPLW+GYLY LL +I+TL+ QYF L++G +RT LI+AIYRK ++S S+R++ +VGE VNLMS+D +R V +N +W APL I+L+LYFLWG LGPS L+GL +MIILIP+NA L+ +++ Q MK KD R++ MNEVL GIKV+KLYAWEPSF+E+I IR+ E++ LK+ +Y+ A +FI++ A F+V+LV+F T+V +D NVLD+E AFVS+S FN++R PL+ P + ++QASVS KR+++F+N+ E D + +E + + + + NG+FAWD + + INL+I++G LVAIVG VG+GKSSLISA+LG+MEK +G VN G +AYV QQAWIQN T++ NILFG +Y V ACAL DF +L GDQTEIGEKGINLSGGQKQRVSLARAVYNN DIY LDDP+SAVD+HVGKHIFE++I SR G++K KTR+LVTH +T+L E D I+V+K+G ISE GT+ +L+ G F+ FL ++ + D S E + + L+ + + EL + + A + + S S+ +K + RK S S N+ + KL+ EK ET +V VY +Y ++IG F+ ++ + AV Q+FS+ N+WL+ WS D ++ + ++MYLG YG G A+T L +G A+ ++HN ++ +L AP++FFDT P GRI++RF KDVD +DT++P + + T+VVI + P+FI V +P+ L Y+FIQ+ Y+ TSRQLKRL S++RSPIYS FGE+++G I+A+ +QD+ + +ES+VD Q Y + ANRWL+VRLEM+GN++I F+ALFAVL +D + G VGLS+SYA QIT L +L+RM S +E N+V+VERI+EY + QEAP+ P + K WP RG++ F DYK RYR GLDLVL G++ + GEKIGIVGRTGAGKSSLT+ALFR+IE + G I ID DI+ LGL LRS +TIIPQDPVLFSG++RLNLDPF +DD IWRAL+ HL ++V GL L E++EGG NLSVGQRQL+CLARALLRKT++L+LDEATAAVDLE DDLIQ TIR+EFKDCT+LTIAHRLNTI+D DRVIVL G I E D P LLQ +S F+ MAK+AGL
Sbjct: 8 QFCGSKFWDANLSWYTDNPDLTECFQKTVLIWVPCIFLWICSSFEAYYLVNSKRKNIPLTWLFISKYIITVALILLTVLDLGKTIRNWVLDNIVYDV--DFLTPCIKILTFILCLVLLIYNKKYGMRTSGLLWMFWCLLAICGIVQYRSLLT----KSYNEIGSLYEYVSYNIYYPLVVMMFLLNFLVDAEPKYSEYP-RVKTPCPEQSASFPSRLTFGWFNSLAWKGFKNPLQTSDLWSMNPNDMAKEIVPLFDKHWNKSLSKVDNSQGANAVFSKSSGRVDFSSGKKKKTASVLPPLCKAFGPIFM-------FGVMLKVVQDIMTFLSPQILKLLIQFTKSKDEPLWKGYLYAVLLFFTAIIQTLVLAQYFHRMLLVGLRMRTALIAAIYRKALRMSNSARKESTVGEIVNLMSVDAQRFMDVTTYINMIWSAPLQIILALYFLWGILGPSVLSGLAVMIILIPVNALLAGKVRNLQIKQMKNKDDRVKLMNEVLSGIKVLKLYAWEPSFEEQILKIRNKEIKVLKQAAYISAGTSFIWSCAPFMVSLVSFATFVLIDEKNVLDSETAFVSLSLFNILRFPLSMLPMMVSYVVQASVSVKRINKFMNSEELDPNNVQHETSEVNPIVIENGNFAWDSEHIEKPMLRNINLQIKQGQLVAIVGSVGSGKSSLISAMLGEMEKLSGKVNTKGKIAYVSQQAWIQNATLQDNILFGSPFNKALYHRVVEACALTPDFKMLPAGDQTEIGEKGINLSGGQKQRVSLARAVYNNADIYFLDDPLSAVDSHVGKHIFENLIGSR-GLIKKKTRILVTHGITYLPEVDHIIVLKDGEISESGTYKELLDKRGSFADFLVQHLQEVKPDEESSEDLMEIKQKLE--NTIGSEELQQKISQARTRASVSI-----SDSTSIADKKSLNGSLHRKPSTDSQQSGSLVQSNNVKEINQNQYKTGEKLIETEKAETGSVKWTVYSHYLQSIGWFLAVSTIIMNAVFQSFSISANLWLSAWSSDNETVVNGTANTYKQNMYLGVYGAFGLGQAMTSFFCDLAPQLGCWLAARQMHNVMMRGVLRAPLTFFDTTPIGRIISRFAKDVDVLDTSLPQQISDTIYCSYEVIATLVVISYSTPMFISVIVPIGLVYYFIQRFYVATSRQLKRLESVSRSPIYSHFGESVTGAQIIRAYGVQDRFVNESESRVDFNQVCYYPSIIANRWLAVRLEMVGNLIIFFSALFAVLDKDTMSAGLVGLSISYALQITQTLNWLVRMTSDVETNIVAVERIKEYSE-TSQEAPWEIP-DQDPPKDWPMRGSVEFHDYKVRYRDGLDLVLNGLSFSVDGGEKIGIVGRTGAGKSSLTLALFRIIEAAYGKIVIDEVDISKLGLHTLRSRLTIIPQDPVLFSGSLRLNLDPFNKCSDDDIWRALEHAHLKDFVKGLPNTLTHEVTEGGDNLSVGQRQLMCLARALLRKTKVLILDEATAAVDLETDDLIQRTIREEFKDCTVLTIAHRLNTILDSDRVIVLDKGSIIEFDSPDNLLQKQDSAFYSMAKDAGL 1532
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. nr
Match: gi|936574272|ref|XP_014219235.1| (multidrug resistance-associated protein 1 isoform X2 [Copidosoma floridanum]) HSP 1 Score: 1380.54 bits (3572), Expect = 0.000e+0 Identity = 727/1554 (46.78%), Postives = 1003/1554 (64.54%), Query Frame = 0
Query: 27 KFCHDPFWDLNTTWFTLDPDFTHCFHQTALVYVPCGLLWLLAPLEIYWINASQSRHIRWNLINVAKCISIALCIILDVISLSLSL-GYFGNNTSWLSLSDILAPLIVFLTHALALILTLMNKKMGLTSSGILFTFWFVLVITSGLTFASVVRFGAFRTITSSWSVEQSMIYTIYFPLVVAISFLTFWADPPPVYWEVEDQVDVPSPEMYASFPSKIAFGWIDTLIKMGWQTPLNQRNIFDLNPNLTTN----ILTKKWAKHEKKVRHPMRGTLKTDLIQTLARCFG-----VDFLIASGLQ------------------ILGVLINQVFFVCCKAVPQTISLLITFSTS-DEPLWRGYLYMSLLVAINMIRTLLNTQYFFIYLVLGQNVRTTLISAIYRKTFKLSASSRRQRSVGETVNLMSIDTERMNIVVGSLNNLWYAPLVILLSLYFLWGYLGPSCLAGLGMMIILIPINAWLSSRIKKYQFANMKKKDQRLETMNEVLEGIKVMKLYAWEPSFQEKIAAIRDSEVETLKKISYLGALQTFIFNSAVFLVTLVTFGTYVYLDPSNVLDAEKAFVSISYFNLMRGPLNQFPQFIIQLIQASVSHKRLDEFLNAPETDSKIIGNEPNSQHAVEVFNGSFAWDDTE-DSSTIHGINLKIERGSLVAIVGQVGAGKSSLISAILGDMEKRTGSVNVDGTVAYVPQQAWIQNDTVRQNILFGRDHFPNIYFETVRACALVEDFTILEQGDQTEIGEKGINLSGGQKQRVSLARAVYNNRDIYLLDDPMSAVDAHVGKHIFEHVISSRTGVLKDKTRLLVTHNVTFLHETDLILVMKNGRISEMGTFNDLMSGGGDFSLFLAEY----GNISEQDAGSVEQVETFQD------TLDMVSNLSQNELNKTPPDPSSPAFLDLNSPLGSTIGSVKIRKRNSAKTFRKRKGKVGPSSSNKTNSREKGKLVVEEKLETSAVSNAVYVYYAKAIGLFVTITIFGLYAVNQAFSVGTNVWLAKWSDDPQSAI-----PKYRDMYLGGYGGLGGASALTVMVVYLIITIGGLNASTKLHNNLLAKILAAPMSFFDTNPKGRILNRFGKDVDAVDTNVPSNFNSICRLLFNTFGTIVVICATNPLFIVVFIPLFLAYWFIQKLYITTSRQLKRLNSIARSPIYSLFGETLSGVPTIKAFNLQDQLIKINESKVDTLQTTTYLNQAANRWLSVRLEMLGNVVILFAALFAVLGRDKVDPGEVGLSLSYATQITTFLTFLIRMMSMIENNMVSVERIQEYEDHVDQEAPYVCPMESTLEKQWPPRGAIRFQDYKTRYRPGLDLVLKGITCDIHAGEKIGIVGRTGAGKSSLTMALFRLIEPSSGTIYIDGTDITTLGLGFLRSNITIIPQDPVLFSGTMRLNLDPFEIATDDQIWRALKLGHLSEYVSGLRYGLDQEISEGGGNLSVGQRQLVCLARALLRKTQILVLDEATAAVDLEMDDLIQTTIRQEFKDCTILTIAHRLNTIMDCDRVIVLRSGLIAEMDEPQKLLQDTNSIFFGMAKNAGL 1535
+FC FWD N +W+T +PD T CF +T L++VPC LW+ + E Y++ S+ ++I + ++K I I+L V+ L ++ + +N + D L P I LT L L+L + NKK G+ +SG+L+ FW +L I + + S++ ++ S+ + + Y IY+PLVV + L F D P Y E +V P PE ASFPS++ FGW ++L G++ PL +++ +NPN + K W K KV + Q F VDF +SG + + GV++ V + PQ + LLI F+ S DEPLW+GYLY LL +I+TL+ QYF L++G +RT LI+AIYRK ++S S+R++ +VGE VNLMS+D +R V +N +W APL I+L+LYFLWG LGPS L+GL +MIILIP+NA L+ +++ Q MK KD R++ MNEVL GIKV+KLYAWEPSF+E+I IR+ E++ LK+ +Y+ A +FI++ A F+V+LV+F T+V +D NVLD+E AFVS+S FN++R PL+ P + ++QASVS KR+++F+N+ E D + +E + + + + NG+FAWD + + INL+I++G LVAIVG VG+GKSSLISA+LG+MEK +G VN G +AYV QQAWIQN T++ NILFG +Y V ACAL DF +L GDQTEIGEKGINLSGGQKQRVSLARAVYNN DIY LDDP+SAVD+HVGKHIFE++I SR G++K KTR+LVTH +T+L E D I+V+K+G ISE GT+ +L+ G F+ FL ++ GN+ + S + +E Q + ++ +SQ + S + D S GS + S + K N+ + KL+ EK ET +V VY +Y ++IG F+ ++ + AV Q+FS+ N+WL+ WS D ++ + ++MYLG YG G A+T L +G A+ ++HN ++ +L AP++FFDT P GRI++RF KDVD +DT++P + + T+VVI + P+FI V +P+ L Y+FIQ+ Y+ TSRQLKRL S++RSPIYS FGE+++G I+A+ +QD+ + +ES+VD Q Y + ANRWL+VRLEM+GN++I F+ALFAVL +D + G VGLS+SYA QIT L +L+RM S +E N+V+VERI+EY + QEAP+ P + K WP RG++ F DYK RYR GLDLVL G++ + GEKIGIVGRTGAGKSSLT+ALFR+IE + G I ID DI+ LGL LRS +TIIPQDPVLFSG++RLNLDPF +DD IWRAL+ HL ++V GL L E++EGG NLSVGQRQL+CLARALLRKT++L+LDEATAAVDLE DDLIQ TIR+EFKDCT+LTIAHRLNTI+D DRVIVL G I E D P LLQ +S F+ MAK+AGL
Sbjct: 8 QFCGSKFWDANLSWYTDNPDLTECFQKTVLIWVPCIFLWICSSFEAYYLVNSKRKNIPLTWLFISKYIITVALILLTVLDLGKTIRNWVLDNIVY--DVDFLTPCIKILTFILCLVLLIYNKKYGMRTSGLLWMFWCLLAICGIVQYRSLLT----KSYNEIGSLYEYVSYNIYYPLVVMMFLLNFLVDAEPKYSEYP-RVKTPCPEQSASFPSRLTFGWFNSLAWKGFKNPLQTSDLWSMNPNDMAKEIVPLFDKHWNKSLSKVDKQFWNSYNYSSSQGANAVFSKSSGRVDF--SSGKKKKTASVLPPLCKAFGPIFMFGVMLKVVQDIMTFLSPQILKLLIQFTKSKDEPLWKGYLYAVLLFFTAIIQTLVLAQYFHRMLLVGLRMRTALIAAIYRKALRMSNSARKESTVGEIVNLMSVDAQRFMDVTTYINMIWSAPLQIILALYFLWGILGPSVLSGLAVMIILIPVNALLAGKVRNLQIKQMKNKDDRVKLMNEVLSGIKVLKLYAWEPSFEEQILKIRNKEIKVLKQAAYISAGTSFIWSCAPFMVSLVSFATFVLIDEKNVLDSETAFVSLSLFNILRFPLSMLPMMVSYVVQASVSVKRINKFMNSEELDPNNVQHETSEVNPIVIENGNFAWDSEHIEKPMLRNINLQIKQGQLVAIVGSVGSGKSSLISAMLGEMEKLSGKVNTKGKIAYVSQQAWIQNATLQDNILFGSPFNKALYHRVVEACALTPDFKMLPAGDQTEIGEKGINLSGGQKQRVSLARAVYNNADIYFLDDPLSAVDSHVGKHIFENLIGSR-GLIKKKTRILVTHGITYLPEVDHIIVLKDGEISESGTYKELLDKRGSFADFLVQHLQEVGNLKPDEESSEDLMEIKQKLENTIGSEELQQKISQARTRASVSISDSTSIADKKSLNGSLHRKPSTDSQQSGSLVQSNNVK----EINQNQYKTGEKLIETEKAETGSVKWTVYSHYLQSIGWFLAVSTIIMNAVFQSFSISANLWLSAWSSDNETVVNGTANTYKQNMYLGVYGAFGLGQAMTSFFCDLAPQLGCWLAARQMHNVMMRGVLRAPLTFFDTTPIGRIISRFAKDVDVLDTSLPQQISDTIYCSYEVIATLVVISYSTPMFISVIVPIGLVYYFIQRFYVATSRQLKRLESVSRSPIYSHFGESVTGAQIIRAYGVQDRFVNESESRVDFNQVCYYPSIIANRWLAVRLEMVGNLIIFFSALFAVLDKDTMSAGLVGLSISYALQITQTLNWLVRMTSDVETNIVAVERIKEYSE-TSQEAPWEIP-DQDPPKDWPMRGSVEFHDYKVRYRDGLDLVLNGLSFSVDGGEKIGIVGRTGAGKSSLTLALFRIIEAAYGKIVIDEVDISKLGLHTLRSRLTIIPQDPVLFSGSLRLNLDPFNKCSDDDIWRALEHAHLKDFVKGLPNTLTHEVTEGGDNLSVGQRQLMCLARALLRKTKVLILDEATAAVDLETDDLIQRTIREEFKDCTVLTIAHRLNTILDSDRVIVLDKGSIIEFDSPDNLLQKQDSAFYSMAKDAGL 1545 HSP 2 Score: 95.5153 bits (236), Expect = 8.964e-16 Identity = 114/453 (25.17%), Postives = 200/453 (44.15%), Query Frame = 0
Query: 1156 LFGETLSGVPTIKAF----NLQDQLIKINESKVDTLQTTTYLNQAANRWLSVRLEMLGNVVILFAALFAVLGRDKVDPGEVGLSLSYATQITTFLTFLIRMMSMIENNMVSVERIQEYEDHVDQEAPYVCPMESTLEKQWPPRGAIRFQDYKTRYRPGLDLVLKGITCDIHAGEKIGIVGRTGAGKSSLTMALFRLIEPSSGTIYIDGTDITTLGLGFLRSNITIIPQDPVLFSGTMRLNLDPFEIATDDQIWRALKLGHLSEYVSGLRYGLDQEISEGGGNLSVGQRQLVCLARALLRKTQILVLDEATAAVDLEMDDLIQTTI---RQEFKDCTILTIAHRLNTIMDCDRVIVLRSGLIAEMDEPQKLLQDTNSIFFGMAKN----AGLMSEQEAK------RQRVSDLLDAELDPKRISEI-----VGVSERTVRNIRAAKKIGNGVERK 1586
L E LSG+ +K + + ++Q++KI ++ L+ Y++ + S M+ ++ FA + ++ +D +SLS + L+ L M+S + VSV+RI ++ + + + V S + G + D + +P +L+ I I G+ + IVG G+GKSSL A+ +E SG + G I + N T+ QD +LF PF A R ++ L+ L G EI E G NLS GQ+Q V LARA+ I LD+ +AVD + I + R K T + + H + + + D +IVL+ G I+E ++LL S + ++ L ++E+ +Q++ + + +E ++IS+ V +S+ T +I K + + RK
Sbjct: 496 LMNEVLSGIKVLKLYAWEPSFEEQILKIRNKEIKVLKQAAYISAGTSFIWSCAPFMVS--LVSFATFVLIDEKNVLDSETAFVSLSLFNILRFPLSMLPMMVSYVVQASVSVKRINKFMNSEELDPNNVQHETSEVNPIVIENGNFAW-DSEHIEKP----MLRNINLQIKQGQLVAIVGSVGSGKSSLISAMLGEMEKLSGKVNTKG-KIAYVSQQAWIQNATL--QDNILFGS-------PFNKALYH---RVVEACALTPDFKMLPAGDQTEIGEKGINLSGGQKQRVSLARAVYNNADIYFLDDPLSAVDSHVGKHIFENLIGSRGLIKKKTRILVTHGITYLPEVDHIIVLKDGEISESGTYKELLDKRGSFADFLVQHLQEVGNLKPDEESSEDLMEIKQKLENTIGSEELQQKISQARTRASVSISDST--SIADKKSLNGSLHRK 926
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. nr
Match: gi|936574281|ref|XP_014219238.1| (multidrug resistance-associated protein 1 isoform X3 [Copidosoma floridanum]) HSP 1 Score: 1379.77 bits (3570), Expect = 0.000e+0 Identity = 727/1554 (46.78%), Postives = 1004/1554 (64.61%), Query Frame = 0
Query: 27 KFCHDPFWDLNTTWFTLDPDFTHCFHQTALVYVPCGLLWLLAPLEIYWINASQSRHIRWNLINVAKCISIALCIILDVISLSLSL-GYFGNNTSWLSLSDILAPLIVFLTHALALILTLMNKKMGLTSSGILFTFWFVLVITSGLTFASVVRFGAFRTITSSWSVEQSMIYTIYFPLVVAISFLTFWADPPPVYWEVEDQVDVPSPEMYASFPSKIAFGWIDTLIKMGWQTPLNQRNIFDLNPNLTTN----ILTKKWAKHEKKVRHPMRGTLKTDLIQTLARCFG-----VDFLIASGLQ------------------ILGVLINQVFFVCCKAVPQTISLLITFSTS-DEPLWRGYLYMSLLVAINMIRTLLNTQYFFIYLVLGQNVRTTLISAIYRKTFKLSASSRRQRSVGETVNLMSIDTERMNIVVGSLNNLWYAPLVILLSLYFLWGYLGPSCLAGLGMMIILIPINAWLSSRIKKYQFANMKKKDQRLETMNEVLEGIKVMKLYAWEPSFQEKIAAIRDSEVETLKKISYLGALQTFIFNSAVFLVTLVTFGTYVYLDPSNVLDAEKAFVSISYFNLMRGPLNQFPQFIIQLIQASVSHKRLDEFLNAPETDSKIIGNEPNSQHAVEVFNGSFAWDDTE-DSSTIHGINLKIERGSLVAIVGQVGAGKSSLISAILGDMEKRTGSVNVDGTVAYVPQQAWIQNDTVRQNILFGRDHFPNIYFETVRACALVEDFTILEQGDQTEIGEKGINLSGGQKQRVSLARAVYNNRDIYLLDDPMSAVDAHVGKHIFEHVISSRTGVLKDKTRLLVTHNVTFLHETDLILVMKNGRISEMGTFNDLMSGGGDFSLFLAEYGNISEQDAGSVEQVETFQDTLDMVSNLSQNELNKTPPDPSSPAFLDLNSPLGSTIGSVKIRKRNSAKTFRKRKGKVGPSSS----------NKTNSREKGKLVVEEKLETSAVSNAVYVYYAKAIGLFVTITIFGLYAVNQAFSVGTNVWLAKWSDDPQSAI-----PKYRDMYLGGYGGLGGASALTVMVVYLIITIGGLNASTKLHNNLLAKILAAPMSFFDTNPKGRILNRFGKDVDAVDTNVPSNFNSICRLLFNTFGTIVVICATNPLFIVVFIPLFLAYWFIQKLYITTSRQLKRLNSIARSPIYSLFGETLSGVPTIKAFNLQDQLIKINESKVDTLQTTTYLNQAANRWLSVRLEMLGNVVILFAALFAVLGRDKVDPGEVGLSLSYATQITTFLTFLIRMMSMIENNMVSVERIQEYEDHVDQEAPYVCPMESTLEKQWPPRGAIRFQDYKTRYRPGLDLVLKGITCDIHAGEKIGIVGRTGAGKSSLTMALFRLIEPSSGTIYIDGTDITTLGLGFLRSNITIIPQDPVLFSGTMRLNLDPFEIATDDQIWRALKLGHLSEYVSGLRYGLDQEISEGGGNLSVGQRQLVCLARALLRKTQILVLDEATAAVDLEMDDLIQTTIRQEFKDCTILTIAHRLNTIMDCDRVIVLRSGLIAEMDEPQKLLQDTNSIFFGMAKNAGL 1535
+FC FWD N +W+T +PD T CF +T L++VPC LW+ + E Y++ S+ ++I + ++K I I+L V+ L ++ + +N + D L P I LT L L+L + NKK G+ +SG+L+ FW +L I + + S++ ++ S+ + + Y IY+PLVV + L F D P Y E +V P PE ASFPS++ FGW ++L G++ PL +++ +NPN + K W K KV + Q F VDF +SG + + GV++ V + PQ + LLI F+ S DEPLW+GYLY LL +I+TL+ QYF L++G +RT LI+AIYRK ++S S+R++ +VGE VNLMS+D +R V +N +W APL I+L+LYFLWG LGPS L+GL +MIILIP+NA L+ +++ Q MK KD R++ MNEVL GIKV+KLYAWEPSF+E+I IR+ E++ LK+ +Y+ A +FI++ A F+V+LV+F T+V +D NVLD+E AFVS+S FN++R PL+ P + ++QASVS KR+++F+N+ E D + +E + + + + NG+FAWD + + INL+I++G LVAIVG VG+GKSSLISA+LG+MEK +G VN G +AYV QQAWIQN T++ NILFG +Y V ACAL DF +L GDQTEIGEKGINLSGGQKQRVSLARAVYNN DIY LDDP+SAVD+HVGKHIFE++I SR G++K KTR+LVTH +T+L E D I+V+K+G ISE GT+ +L+ G F+ FL ++ + D S E + + L+ + + EL + + A + + S S+ +K + RK S S N+ + KL+ EK ET +V VY +Y ++IG F+ ++ + AV Q+FS+ N+WL+ WS D ++ + ++MYLG YG G A+T L +G A+ ++HN ++ +L AP++FFDT P GRI++RF KDVD +DT++P + + T+VVI + P+FI V +P+ L Y+FIQ+ Y+ TSRQLKRL S++RSPIYS FGE+++G I+A+ +QD+ + +ES+VD Q Y + ANRWL+VRLEM+GN++I F+ALFAVL +D + G VGLS+SYA QIT L +L+RM S +E N+V+VERI+EY + QEAP+ P + K WP RG++ F DYK RYR GLDLVL G++ + GEKIGIVGRTGAGKSSLT+ALFR+IE + G I ID DI+ LGL LRS +TIIPQDPVLFSG++RLNLDPF +DD IWRAL+ HL ++V GL L E++EGG NLSVGQRQL+CLARALLRKT++L+LDEATAAVDLE DDLIQ TIR+EFKDCT+LTIAHRLNTI+D DRVIVL G I E D P LLQ +S F+ MAK+AGL
Sbjct: 8 QFCGSKFWDANLSWYTDNPDLTECFQKTVLIWVPCIFLWICSSFEAYYLVNSKRKNIPLTWLFISKYIITVALILLTVLDLGKTIRNWVLDNIVY--DVDFLTPCIKILTFILCLVLLIYNKKYGMRTSGLLWMFWCLLAICGIVQYRSLLT----KSYNEIGSLYEYVSYNIYYPLVVMMFLLNFLVDAEPKYSEYP-RVKTPCPEQSASFPSRLTFGWFNSLAWKGFKNPLQTSDLWSMNPNDMAKEIVPLFDKHWNKSLSKVDKQFWNSYNYSSSQGANAVFSKSSGRVDF--SSGKKKKTASVLPPLCKAFGPIFMFGVMLKVVQDIMTFLSPQILKLLIQFTKSKDEPLWKGYLYAVLLFFTAIIQTLVLAQYFHRMLLVGLRMRTALIAAIYRKALRMSNSARKESTVGEIVNLMSVDAQRFMDVTTYINMIWSAPLQIILALYFLWGILGPSVLSGLAVMIILIPVNALLAGKVRNLQIKQMKNKDDRVKLMNEVLSGIKVLKLYAWEPSFEEQILKIRNKEIKVLKQAAYISAGTSFIWSCAPFMVSLVSFATFVLIDEKNVLDSETAFVSLSLFNILRFPLSMLPMMVSYVVQASVSVKRINKFMNSEELDPNNVQHETSEVNPIVIENGNFAWDSEHIEKPMLRNINLQIKQGQLVAIVGSVGSGKSSLISAMLGEMEKLSGKVNTKGKIAYVSQQAWIQNATLQDNILFGSPFNKALYHRVVEACALTPDFKMLPAGDQTEIGEKGINLSGGQKQRVSLARAVYNNADIYFLDDPLSAVDSHVGKHIFENLIGSR-GLIKKKTRILVTHGITYLPEVDHIIVLKDGEISESGTYKELLDKRGSFADFLVQHLQEVKPDEESSEDLMEIKQKLE--NTIGSEELQQKISQARTRASVSI-----SDSTSIADKKSLNGSLHRKPSTDSQQSGSLVQSNNVKEINQNQYKTGEKLIETEKAETGSVKWTVYSHYLQSIGWFLAVSTIIMNAVFQSFSISANLWLSAWSSDNETVVNGTANTYKQNMYLGVYGAFGLGQAMTSFFCDLAPQLGCWLAARQMHNVMMRGVLRAPLTFFDTTPIGRIISRFAKDVDVLDTSLPQQISDTIYCSYEVIATLVVISYSTPMFISVIVPIGLVYYFIQRFYVATSRQLKRLESVSRSPIYSHFGESVTGAQIIRAYGVQDRFVNESESRVDFNQVCYYPSIIANRWLAVRLEMVGNLIIFFSALFAVLDKDTMSAGLVGLSISYALQITQTLNWLVRMTSDVETNIVAVERIKEYSE-TSQEAPWEIP-DQDPPKDWPMRGSVEFHDYKVRYRDGLDLVLNGLSFSVDGGEKIGIVGRTGAGKSSLTLALFRIIEAAYGKIVIDEVDISKLGLHTLRSRLTIIPQDPVLFSGSLRLNLDPFNKCSDDDIWRALEHAHLKDFVKGLPNTLTHEVTEGGDNLSVGQRQLMCLARALLRKTKVLILDEATAAVDLETDDLIQRTIREEFKDCTVLTIAHRLNTILDSDRVIVLDKGSIIEFDSPDNLLQKQDSAFYSMAKDAGL 1542 The following BLAST results are available for this feature:
BLAST of multidrug resistance-associated protein 1 isoform x4 vs. L. salmonis genes
Analysis Date: 2018-04-19 (T. kinsejongensis vs L. Salmonis peptides) Total hits: 22
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BLAST of multidrug resistance-associated protein 1 isoform x4 vs. SwissProt
Analysis Date: 2018-04-19 (T. kingejongensis peptided Blastp vs. SwissProt) Total hits: 25
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BLAST of multidrug resistance-associated protein 1 isoform x4 vs. nr
Analysis Date: 2018-05-15 (T. kingsejongensis proteins Blastp vs. NR) Total hits: 25
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The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at scaffold81_size397536:189818..201321+ Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>maker-scaffold81_size397536-snap-gene-2.18 ID=maker-scaffold81_size397536-snap-gene-2.18|Name=multidrug resistance-associated protein 1 isoform x4|organism=Tigriopus kingsejongensis|type=gene|length=11504bp|location=Sequence derived from alignment at scaffold81_size397536:189818..201321+ (Tigriopus kingsejongensis)back to top Synonyms
The feature 'multidrug resistance-associated protein 1 isoform x4' has the following synonyms
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