Query:   40 SFPIIGHT-WMIGDDIPRYMDRCAEKYGPIFRFDMGYLPTVIIGRYDDYVDACKMEPMNGR--AWSIMPFVRYLFGTDSKGEVYGVVSSNGPVWAEQRKFMHINLNRVGMGKSKKLEQIVEQEVEVMCERVAKLSEV--GGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMLELTDCINRHF-ETLSPSNPISTLQQYFHRSTKFATDLGIIEGFQGILKLRDNVAEQISEFQPDHEGNFVERYLFEIQSAHPESSFYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSAKPSMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGKFVFDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNFKIK-------PAPGQVYTLKSNPGLAFTSDPYQAIVESR 500
            + PI+G   +M G       D    KYG ++   +G +  V+I  Y    D    E ++ R   W       +       G   G+++++G VW EQR+F   NL   G GK+  L+ +++ E     E + K S+   G +  +    V I N++W++I G    +D+    E+   ++  + E  S  + I   + +  R  +    L   E F      R  + E + ++   +  +F++ Y+ E+     E+ F+     E L    ++ F AG ET+AT L W+  ++ +YPE Q K   E+  VLG   PS +   ++ Y +A + E+ R+  +G  ++P +T+  + ++G  IP+ T+I  N+   + +P  FP P  FRPERF+ ++GK    E  + FG GKR C+GE +AK ++F+F   M+   KI        P P + YT+    G+     P+   V SR
Sbjct:   32 NLPIVGTLPYMNGIGSNALTDPKFGKYGDLYSLFIGNIHLVVINNYQLAKDLFAREDVSYRRETW-------WTLNVRGDGHPLGIINTSGHVWKEQRRFAVRNLKDFGFGKNT-LDAVIQNEARFTIEDIIKESKNNNGVLRMESTFNVGIINILWQIIAGYRFDKDNEKTKEMMGHLHEVYSEGYSILHYIPAARFFIKRDKRMDDMLRTKEFF------RSQIREHMKDYDASNPRDFIDVYIKEMLDEDREN-FH----EEQLMTTCLDFFQAGGETSATTLLWSVLYISLYPEAQAKCVEEIEAVLGKEDPSQEVYKDMVYCNATLMEIQRMASVGPLTLPHVTIKDLFIDGYCIPRGTEIYGNIIAFHNNPKFFPSPKSFRPERFI-ENGKLKKLEAFAPFGVGKRICMGESMAKNQLFIFFVMMLQKLKISVSENHGVPDP-EAYTM----GITKIPKPFYISVSSR 480          

Query:    5 VVGVAALTLIGVYAVKYFKKYFWDFRHLNGPSPLLSFPIIGHTWMIGDDIPRYMDRCAEKYGPIFRFDMGYLPTVIIGRYDDYVDACKMEPMNGRAWSIMPFVRYLFGTDSKGEVYGVVSSNGPVWAEQRKFMHINLN--------RVGMGKSKKLEQIVEQEVEVMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMLELTDCINRHFETLSPSNPISTLQQYFHRSTKFATDLGIIEGFQGIL-KLRDNVAEQIS-----------EFQPDHEGNFVERYLFEIQSAHPESSFYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSAK-PSMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGKFVFDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNFKIKPAPGQVY-TLKSNPGLAFTSDPYQAIVESR 500
            +V +A LTL+  Y +K+ KK F D      P P+  +PI+G   +I  +    +   A K+G I    MG    V++  Y     A   +  + R  + +     L G       YG+V+S GP+W  QRK++   LN        + G G  +++E +V +EV+     +        V+   L   A++NVI  +I  +  +  DP         +  F   + +  ++           F   L ++ G      KLR N  E I+           E  P +  + ++ YL  +Q + P+  F   D  + L    ++LF A  ETT T L W   F++  P++  K+  EL  V+G    P +    +LPYT A + E+ R + +        T  ++   G  +P+++ ++P +  ++ +P ++ +P EFRPERF++++G     E    FG G+RKC+G+ LA+ E FLF T +VH F +   P Q   +L+   G+  T   +   ++ R
Sbjct:   16 IVLIAFLTLL--YILKHLKKSFKDL----PPGPI-GYPIVGIIPLIKKEFHLLLFDYAMKFGKIVSLKMGGETVVVLSDYQTIKKAFSCKYFSARPKTEL---SQLLGG------YGIVNSEGPLWKTQRKYL---LNQKLGMKHWKSGAGSLEQIESVVSREVQSFLYTLENDYSNTFVNLTPLFNCAVSNVICSIIXSRRFRYQDPKFQRFMFLFDEGFRLFTMTGAMT-----------FLPFLKVLPGISDTCTKLRQNREEMIAFVREIISEHRQELDPQNPKDLIDSYL--VQESTPDQFFEDYDPEQQLEQIILDLFSASVETTRTSLLWAIVFMLHNPKILSKVRDELNSVVGEDNLPQLSDMIKLPYTRATLYEIMRRSSVVPMGTTHATDREVQFEGFVLPQNSHVIPLIHAVHMNPKNWENPEEFRPERFINKEGVLFKPEHFMPFGVGQRKCLGDRLAEQEFFLFFTSLVHVFDLGNNPEQTMPSLRGTAGVTVTPSEFSVHIKLR 501          

Query:    1 MSSTVVGVAALTLIGV-YAVKYFKKYFWDFRHLNGPSPLLSFPIIGHTWMI---GDDIPRYMDRCAEKY--GPIFRFDMGY-LPTVIIGRYDDYVDACKMEPMNGRAWSIMPFVRYLFGTDSKGEVY------GVVSSNGPVWAEQRKFMHINLNRVGMGKSKKLEQIVEQE---VEVMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMLELTDCINRHFETLSPSNPISTLQQYF----------HRSTKFATDLGIIEGFQGILKLRDNVAEQISEFQPDHEGNFVERYLFEIQSA--HPE---SSFYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSA------KPSMDRRDELPYTHAAIQEVYR---LNPMGFFSVPRLTLS-QINLNGIPIPKHTQIMPNLRTINRDPTSF-PDPNEFRPERFLD--QDG--KFVFDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNFKIKPAPGQVYTLKSNPGLAFTSDPYQ 494
            MS  +V    L L  + Y +K      W +     P+P    P+ GH+  +   G +     DR  +++  G +    +   +   +I  +D      K + +N R       + + F  D   ++Y      G + S G +W +QR+FM   L   G G+S   + ++E+    V  + E    +   G +    L  + I NV+WR++ G   +  DP   EL   +++  + +  +N   T+   F              +  + +  +  F     L+  V    + F P+H  +F++ YL +I+ +  +P+    SF G+ G+ +L    ++LF AG+ETT++ L+W   F++ +PE+Q+K+  EL   L         K   + R  LPYT A I E+ R   + PMG   VP  T S    +    +PK   +   L  I R+P  F P+P++F P+RFL+   DG  KF+ +E +  F  GKR C GE LA+ EIF F T ++  F+++   G++ +     G+     P+ 
Sbjct:    1 MSVALVITVCLILAXILYEIK------WKYPENYPPTPPFRLPLFGHSLYLRSAGKNFQEGFDRIFDRFNVGGVLCLQVAARIRMXMISDFDILKKILKTDDLNYR-------LAHDFSIDYTKKLYQGIGVDGXLWSYGXIWKQQRRFMLSTLKNFGFGRSSMEDMLMEEATLFVNFLNEE--NIQTGGNIRIANLFNIGILNVLWRIVAGTRFEYRDP---ELQKIVHKVGDAILSTNLKPTIAAIFPFLRTIYPGIDDXQEVTSKVAAVYEF-----LQTAVKNHEANFDPNHPRDFIDTYLLKIKDSEENPDKENDSFRGELGKLNLSKTLLDLFFAGSETTSSTLSWGVLFMVRHPEIQKKVQEELDLFLHEGDGESFRKARSEDRIHLPYTEAXICEIQRRGNITPMG---VPHATYSGDAKVGDYVVPKGHVVNAYLSGIFRNPKYFGPNPDQFNPDRFLEVASDGGVKFIKNEYLIPFSIGKRSCPGENLARMEIFSFFTSILQRFELRSIDGEIPSTDFISGITSIPKPFN 514          

Query:   18 AVKYFKKYFWDFRHLNGPSPLLSFPIIGHT-WMIGDDIPRYMDRCAEKYGPIFRFDMGYLPTVIIGRYDDYVDACKMEPMNGRA---WSIMPFVRYLFGTDSKGEVYGVVSSNGPVWAEQRKFMHINLNRVGMGKSKKLEQIVEQEVEVMCERVAKLSEV--GGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMLELTDCINRHFETLSPSNPISTLQQYFHRSTKFATDLGIIEGFQGILKLRDNVAEQISEFQPDHEGNFVERYLFEIQSAHPESSFYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVL-GSAKPSMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGKFV-FDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNFKIKPAPGQ 476
            A+ YFK+  W  R   GP  L   P++G   +M G      ++    K+G ++   +G +P ++I  +    +    E ++ R    W+I   VR     D K +  G++++ G  W  QR+F    L   G GK + L+ ++++E +   + + + S    G V       V+I NV+W+++ G+    ++    E  + +N  F           + +YF +  +    +  ++ F      R+ + E I +   D+  +F++ YL E+  +  + S++     E L                               +Q+K   E++  L G  KP+ D   ELPYTHA + EV RL  +G  S+PR T   I++NG  IP+ T+I  N    +RDP  FP+P EF+PERFL +DG  V  DE    FG G+R C+GE LA+ ++ +F   ++ N  I    GQ
Sbjct:    2 ALGYFKRKRWVARFPPGPRNL---PLVGSIPFMNGIGTQGCLNPDYRKFGDLYTLFIGPIPLIVINSFQLTKELYVKEEISSRRDTWWTIN--VR----GDGK-QSLGIINTGGMKWQTQRRFALRQLREFGFGK-RSLDSVIQEEAQASIDTILQESSKNDGKVLMASNFNVSIINVLWQIVAGQRFDPEESSTKERMEHLNEVFRVGYSVLHYLPIARYFIKKDERRDKMLSLKEF-----FREMIREHIKDQDDDNPRDFIDVYLKEVHKSGEKPSYFHI---EQL-------------------------------IQKKCKEEIKDKLQGDEKPTQDCISELPYTHATLMEVQRLASVGPMSLPRYTTKDIDVNGYSIPEGTEIYSNFMAFHRDPDFFPEPLEFKPERFLTEDGSRVKKDEHFLPFGLGRRICMGESLARHQLIIFFIMILQNLNISVPIGQ 418          

Query:   35 PSPLLSFPIIGHT-WMIGDDIPRYMD-RCAEKYGPIFRFDMGYLPTVIIGRYDDYVDACKMEPMNGR---AWSIMPFVRYLFGTDSKGEVYGVVSSNGPVWAEQRKFMHINLNRVGMGKSKKLEQIVEQEVEVMCERVAKLSE-VGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMLELTDCINRHFETLSPSNPISTLQQYFHRSTKFATDLGIIEGFQGILKLRDNVAEQISEFQPDHEGN----FVERYLFE-IQSAHPESSFYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSAKPSMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGKFVFDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNFKIK-----PAPGQVYTLKSNPGLAFTSDPYQAIVESR 500
            P P  S P++G   ++     P  +D    EK+G I+  D+ +   V++  +    D    E ++GR    W      R+  G D  G  YG++++ GP+W  QR+F   NL  +G GK K LE ++  EV  + E + ++ +    V    +  V I NV+W +I     +       E+ + +    +     N   ++         FA  + + E  + +L ++  +++   E + + E N    F++ YL E ++S  P  S      ++ L     + F+AG+ETT+T L W    + ++ ++Q K   E+   +G+  P  +    LP+T A I EV R   +   S+    L  I +    IPK T ++ N    + DP  FP P+EF P RF     K    E+   +G GKR C+G+ LAK ++F F   +V N+ I+     P P      K   G+    DP+   ++ R
Sbjct:   31 PGPF-SLPLVGSLPFLSSQGSPGILDFALGEKFGSIYTVDVIWSKIVVLNDFGMAKDLFNREDVSGRYQGQWH-----RFTKGYD--GIAYGIINNEGPMWQSQRRFALTNLKNLGFGK-KSLESVIYNEVHHLFEVIDEMIDGCSDVLIHDIFHVPIINVLWSIIASHRFEYSQ--AREIVEKLGLDLKKGIHINIFISI---------FANYVPLNESDEAMLYMKRFISKNXDEHKNNLEVNAPKDFIDFYLIEMLKSQDPYFS------KKQLIVMLFDFFLAGSETTSTTLLWIILLMCLHNDIQLKCYQEISQNIGNNFPREEDMKMLPFTLATISEVQRYANIAPASLVHKVLQTIRVGKYLIPKGTSVIANYHKFHMDPKVFPHPHEFNPYRFY----KVPKPEQFVPYGFGKRICMGKSLAKKQLFYFFVMIVQNYIIRVPKDNPRPD---PKKCTMGITSVPDPFYVNIQKR 479          

Query:  117 GEVYGVVSSNGPVWAEQRKFMHINLNRVGMGKSKKLEQIVEQEVEVMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMLELTDCINRHFETLSPSNPISTLQQYFHRSTKFATDLGIIEGFQGILKLRDNVAEQISEFQPDHEGNFVERYLFEIQSAHPESSFYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSAKPSMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGKFVFDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNFKIK 471
            G  YG+ SS G +W  QR+F  + L  +G GK      I EQ + +      +      +  + +  + + NV+W+++  K+    +    ++   +N  F     +N    L+++ H       D   ++  Q + +L D   + + E  P+   +F++ YL E++  + +S+F     ++ L    ++LF+AG ETT T L W   ++ +Y  VQEK + E+  VLGS  P  +    LPYT A + E+ RL      S+P   L  I +    +PK T  + NL   + DP  F +P +F P+R+L         ++   FG GKR C+G  LAK E++ F   ++  F I+
Sbjct:   12 GIAYGIASSEGILWQNQRRFSLMKLKNLGFGKKSIEIIIYEQIINLFEMIETQKDSFNDLFIKDIFTIPVVNVLWKIVASKSYDWRNSGERKVXAAVNEVFGAAYETNFF--LEKFRHFLPYDIADKSTLKLRQIMEELIDEHTQNLDENSPN---DFMDVYLIEMKK-NVDSTF----SKKQLASLCIDLFLAGAETTNTTLVWALLYMSLYEGVQEKCAEEINSVLGSRMPQEEDMKNLPYTIATLNEIQRLCNTAPASLPHKNLKDIKIGDYVVPKGTLFLANLIGFHHDPNIFENPQQFNPDRWLHYKS---CPQQFVPFGFGKRICMGVSLAKKELYYFFVMLIKMFIIR 353          

Query:   57 YMDRCAEKYGPIFRFDMGYLPTVIIGRYDDYVDACKMEPMNGRAWSIMPFVRYLFGTDSKGEVYGV-VSSNGPVWAEQRKFMHINLNRVGMGKSKKLEQIVEQEVEVMCERV---AKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMLELTDCINRHFE-------TLSP-SNPISTLQQYFHRSTKFATDLGIIEGFQGILKLRDNVAEQISEFQPDHEGNFVERYLFEIQSAHPESSFYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVL-GSAKPSMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGKFVFDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNFK 469
            + D+  + YG  FR   G   T+I+   +        E  N    S  PF + L    S G+  G+ + + G  W   R+F       +  G S  L Q  + EV  +   +   AK  +    +      + I N+IW ++ G+  K  DP + +  D +    E       T+ P +  I  L++ ++R         I+        L   V E+  +   D +  F++ +L + Q    ++ +      E L     + F+AG ET++  L     ++++YP +QE  + E+R  +    +     R  LPYT A + EV R       +  R +   I +NG   P +  +  NL  + R    +  P+ F P RFL++ G          FG G+R+C+GE +     FL +++++HNFK
Sbjct:   68 FFDKLHDIYGEDFRLHNGIEDTIILSSLNGI-----REFSNHPNASFRPFNKVLMDIYSDGKDLGMGLGTGGERWKFLRRFSSSAFKSLSGGASG-LNQNFDLEVSEIVAXLRGKAKSPDPIIRNVNIYFDIPILNIIWWLVAGRRYKYGDPAIQKQFDYLKVLLEEPFIAPLTIIPFALYIPPLRKIYNRIRNAMNSFRIL--------LSKIVEERRKDNFTDEKRGFIDLFL-KAQLDDKDNPYLSN---EDLIMCCQDFFLAGAETSSKTLCTFILYMVLYPNIQENAASEIRDAIQKDTQIKSKDRHLLPYTDAVLMEVRRYATPFPITPFRCSNKDIRVNGFDXPANVPVQVNLNGVLRSKYCWKAPDIFNPSRFLNEKGAVEIPNAFMPFGFGRRRCIGEDIGNISNFLIVSNLLHNFK 475          

Query:   29 FRHLNGPSPLLSFPIIGHTWMIGD-DIPRYMDRCAEKYGPIFRFDMGYLPTVIIGRYDDYVDACKMEPMNGRAWSIMPFVRYLFGTDSKGEVY----GVVSSNGPVWAEQRKFMHINLNRVGMGKS--KKLEQIVEQEVEVMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMLELT-DCINRHFETLSPSNPISTLQQYFHRSTKFATDLGIIEG-FQGILKLRDNVAEQISEFQPDHEGNFVERYLFEIQSAHPESSFYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSAKPSMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGKFVFDERV----SL-FGKGKRKCVGEVLAKAEIFLFLTHMVHNFKIKPA 473
            +R +  PS L+     G  +M  D +I  +++R    YG I++F     P V++     + +   +   +   W   P    +    S+ E+Y    G++SS G  W + R  +   L R  + K+  +++  +VE  ++ + E   +  +      + L    + +      TG  +      +L  + D  +   E ++    I +L QY  R+  +   +G++ G ++ I K  + + E   ++  D +   +ER      ++  E+ ++    +  L   A+++ MAG +T A  +++ F ++    +VQEK+  E+R  L    P+    +   Y  A ++EV RL P  + +V R+  + I L+   I + + I+     +  DP    DP EFRPER++     +   ER+    SL FG G R CVG+  A  E+ L L  ++  +K++P 
Sbjct:   13 YRSIPQPS-LIDLKRNGFPFMNYDTEIIPFLERSRLVYGDIYKFKAPLGPDVVVLFKPHHAE---IAYRSAGKWPNRPGFHAIQQFRSQKELYSNNSGLLSSQGQDWYDFRSKVQTALLRPRLIKAYHQRVNGVVEDFIKDIFENTLEDGKASADLLEYLYQWGLES------TGVLAFDRRLGVLNPSLDSSSESQEIINLVQEIFSLSQYLERNMVWKY-IGLLHGKYRQITKCLNRLEELTIKY-VDEKIEMIERKGSCSDTSVIENLYHAGCDKNVLCVLALDMLMAGVDTAANEISFAFHYIAQNQKVQEKLFNEIRS-LDIDDPNF--VENAVYLRATLKEVLRLKPTAYVNV-RMCQNSIELDDYLIQEGSMILFCHIVMCHDPRFVNDPLEFRPERYIKSHPHY---ERLQPFTSLPFGYGPRVCVGKRFANLEMGLLLARIISKYKLEPT 452          

Query:  298 EHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSAKPSMDRRD--ELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGKFVFDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNFKIKPA 473
            E +  QA+  F+AG  TT+T L      L  +PE+QEK+  E+         S + +D  E  YT A I+E  R+ P     + R+      + GIPI K T I   +   + +P  FP+PNEF+PERF  ++   +       FG G R C+    A  E  L L  +V  F+I P 
Sbjct:  298 EIITAQAIIFFIAGYSTTSTTLCCLTYMLATHPEIQEKLYKEI--------VSSEDKDFSEHSYTSAVIKETLRMYPPVALHL-RVCAKDTEVEGIPIKKGTIIEMPIYASHYNPEFFPNPNEFKPERFFQENNLEIIPNTYRPFGNGNRSCIAYRFAMMEXQLILEKLVKKFEILPT 466          

Query:  296 GREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSAKPSMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGKFVFDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNFKIKPA 473
              E +  QAV  F+AG  TT+  L      L   PE+Q+++  E   +L S     D   E  YT A I+E  RL P       R+      + GI I   T I   +   +  P  FP+P EF+PERF  ++   +  +    FG G R C+    A  E+ + +  +V  F+I P 
Sbjct:  284 NNEIITAQAVIFFVAGYVTTSHSLCCLIYVLATNPEIQDQLYQE---ILSSEDQGFD---EHSYTSAVIKEALRLYPPATMHT-RVCTHDTEVEGIFIKNGTIIEMPIYASHYYPEFFPNPEEFKPERFFKENNSEIIPDTFRPFGDGNRICIAYRFAMMELQIVIEKLVKKFEIIPT 454          

Query:   62 AEKYGPIFRFDMGYLPTVIIGRYDDYVDACKMEPMNGRAWSIMPFVRYLFGTDSKGEVYGVVSSNGPVWAEQRKFMHINLNRVGMGKSKKLEQIVEQEVEVMCERVAKLSEVG--GVDFQKLLPVAINNVIWRMITGKTSKQDDPFMLELTDCINRHFETLSPSN-------PISTLQQYFHRSTKFATDLGIIEGFQGILKLRDNVAEQISEFQPDHEGNFVERYLFEIQSAHPESSFYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSAK-PSMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGKFVFDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNFKIKPAP-GQVYTLKSNPGLAFTSDPYQA 495
            + +YGP+    +G    V+   YD   D    +  +GR         Y F   + G+  GVV ++GPVW EQR+F   +L ++G+G S+ +E  +E+E   +   + + S  G   +    +  + + N +W M+ G     DD  +++L D +++ F  + PS        P+  +       T   T L  I  F     LR+ + +    F  D+  + ++ +L E++++  +++   +D    L    ++LFMAG+ETT+  L +   ++++YP+VQ ++  EL   +G+ + P++  R  L Y  A + E+ R   +    +P   L    L G  IPK T ++ ++ +++RD   + DP  FRPERF+  +G    D+    FG GKR+C+GE LAKA +FLF + ++HNF I P+    + +L+   G+  +  P+ A
Sbjct:   57 SSRYGPVTGMRLGTDYIVVACGYDAIRDILLRDEFDGRPDG------YFFRLRTFGKRMGVVFTDGPVWQEQRRFCMQHLRKLGLG-SRSMEAHIEEEARDLVASLHRRSNGGLTAIPMHDVFDICVLNSLWAMLAGHRFDLDDQRLVDLLDIVHKCFRMIDPSGGLLNQMPPLRFIAPRHSGYTNLMTHLNRIWNF-----LRETIDDHRKSFNADNMRDLIDLFLREMETSKCQNNSSFED--LQLVSLCLDLFMAGSETTSNTLGFAVLYMLLYPQVQRRVQDELDRCVGTDRQPTLQDRRSLRYLEAVLMEIQRHATIAPSGIPHKALKNTVLMGHTIPKGTTVLVSMWSLHRDVQHWGDPEVFRPERFISGNGNIKQDDWFMPFGIGKRRCIGETLAKASLFLFFSTLLHNFSILPSSESPLPSLEGYDGVTLSPKPFSA 487          

Query:    7 GVAALTLIGVYAVKYFKKY-FWDFRHLNGPSPLLSFPIIGHTWMIG-DDIPRYMDRCAEKYGPIFRFDMGYLPTVIIGRYDDYVDACKMEPMNGRAWSIMPFVRYLFGTDSKGEVYGVVSSNGPVWAEQRKFMHINLNRVGMGKSKKLEQIVEQEVEVMCERVAKLSEVG-GVDFQKLLPVAINNVIWRMITGKTSKQDDPFMLELTDCINRHFETLSPSNPISTLQQY--FHRSTKFATDLGIIEGFQGILKLRDNV-AEQISEFQPDHEG-NFVERYLFEIQSA--HPESSFYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSAK-PSMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGKFVFDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNFKIKPAPGQ 476
             VA  T+I +  V    ++  W  R   GP P   +P++G+   +   ++P  + +   +YG +F   MG+ P V+I       +       +      +P   YL      G    V++  GP W EQR+F    L   G+GK K LE  V +E   +C+  A  ++ G  ++   +L  A+ NVI  +I  +  + +DP+++ +   +   F  +S   P   L ++  F R    A D+ + +G +  + + DN+  E  + + PD    N  + +L EI+ A  +PESSF      E+L     +LF AG  TT+T L+W    +I++P+VQ ++  E+  V+G  + P M  +  +PYT+A I EV R   +    +PR+T   I +    + K + ++PN+ ++ +D T +  P  F PE FLD  G FV  E    F  G R C+GE LA+ E+FLF T ++  F I    GQ
Sbjct:   11 SVAIFTVIFILLVDLMHRHQHWTSRCPPGPVP---WPVLGNLLQVDLGNMPYSLYKLQNRYGDVFSLQMGWKPMVVINGLKAMKEVLLTCGEDTADRPQVPIFEYL--GVKPGSQGVVLAPYGPEWQEQRRFSVSTLRNFGLGK-KSLEDWVTKEARHLCD--AFTAQAGQSINPNTMLNNAVCNVIASLIFARRFEYEDPYLIRMLKMLKECFTEISGFIP-GVLNEFPIFLRIPGLA-DM-VFQGQKSFMAILDNLLTENRTTWDPDQPPRNLTDAFLAEIEKAKGNPESSF----NDENLRMVVGDLFTAGMVTTSTTLSWALLLMILHPDVQRRVQQEIDAVIGQVQHPEMADQARMPYTNAVIHEVQRFGDIAPLPLPRITSRDIEVQDFLVTKGSTLIPNMSSVLKDETVWEKPLRFHPEHFLDAQGHFVKPEAFMPFSAGHRSCLGEALARMELFLFFTCLLQRFSISVPDGQ 475          

Query:   34 GPSPLLSFPIIGHTWMIG-DDIPRYMDRCAEKYGPIFRFDMGYLPTVIIGRYDDYVDACK--MEPMNGRAWSIMPFVRYLFGTDSKGEVYGVVSSNGPVWAEQRKFMHINLNRVGMGKSKKLEQIVEQEVEVMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMLELTDCINRHFETL-SP----SNPISTLQQYFHRSTKFATDLGIIEGFQGILKLRDNVAEQISEFQPDHEGN----FVERYLF--EIQSAHPESSFYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSAK-PSMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGKFVFDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNFKIKP 472
            GP+P   FPI+G+   +   D+ + +   ++ YGP+F   +G  PTV++  Y+   +A       ++GR+       R+L  T    + +GV+ SNG  W E R+F  + L   GMGK + +E+ V++E   + E + K +     D   +L  A  NVI  +I        D   L L    N +F+ L SP     N    L  YF  S + A         + I  +++ + EQI E Q   + N    F++ +L   E +  + +S F      E+L     ++FMAGTETT+T L +    L+ +PEV  K+  E+  V+G  + P M  R  +PYT A + E+ R   +   +VP  T+  +      IPK T ++ +L ++  D   FP+P+ F P  FLD  G F   +    F  GKR CVGE LA+ E+FLFLT ++ NF  KP
Sbjct:   32 GPTP---FPILGNVLQLDFKDLSKSLTNLSKVYGPVFTVYLGMKPTVVVHGYEAVKEALVDLGHELSGRS-------RFLV-TAKLNKGFGVIFSNGKRWTETRRFSLMTLRNFGMGK-RSIEERVQEEAHCLVEELRK-TNASPCDPTFILGAAPCNVICSVIFQNRFDYTDQDFLSLMGKFNENFKILNSPWVQFCNCFPILFDYFPGSHRKAV--------KNIFYVKNYITEQIKEHQKSLDINNPRDFIDCFLIKMEQEKCNQQSEF----TIENLLTTVSDVFMAGTETTSTTLRYGLLLLMKHPEVIAKVQEEIERVIGRHRSPCMQDRSRMPYTDATVHEIQRYINLIPNNVPHTTICNLKFRNYLIPKGTDVLTSLSSVLHDDKEFPNPDRFDPGHFLDASGNFRKSDYFMPFSTGKRVCVGEALARMELFLFLTAILQNFTPKP 460          

Query:   41 FPIIGHTWMIGDDIPRYMDRCAEKYGPIFRFDMGYLPTVIIGRYDDYVDACKMEPMNGRAWSIMPFVRYLFGTDSKGEVYGVVSSNGPVWAEQRKFMHINLNRVGM-----GKSKKLEQIVEQEVEVMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMLELTDCIN---RHFETLSPSNPISTLQQYFHRST---KFATDLGIIEGFQGILKLRDNVAEQISEFQPDHEGNFVERYLFEIQSAHPESS----FYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSAK-PSMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGKFVFDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNFKIKPAPGQ-VYTLKSNPGLAFTSDPYQAIVESR 500
             P+IG+   +G +        A++YG +F   +G   TV++  Y    +  + E   GR  +  PF++ L G       YG+++S G +W +QR+F+H  L + GM     GK +  ++I+ +  E +    A  S+   VD   ++ VA++NVI  ++       DDP        I    R F  +   + I T+Q +   ST   K A +   ++ F      +D + +    F P++  + V+ YL EI+ A  E +    F GK+  E L    ++LF AG ET  T L W   F++  P+   ++  EL  V+G  + P+++    LP T + I E  R + +   +        + LNG  IP  + ++P + +++ DP  +  P EFRP RF+D +GK    E    FG G+R C+G+VLA+ E+FLF    +H F I    GQ + +LK N G   T + ++  ++ R
Sbjct:   60 LPVIGYLLFMGSEKHTRFMELAKQYGSLFSTRLGSQLTVVMSDYKMIRECFRREEFTGRPDT--PFMQTLNG-------YGIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHA--SDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRF-----YQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVCLKRR 520          

Query:    7 GVAALTLIGVYAVKYFKKY-FWDFRHLNGPSPLLSFPIIGHTWMIG-DDIPRYMDRCAEKYGPIFRFDMGYLPTVIIGRYDDYVDACKMEPMNGRAWSIMPFVRYLFGTDSKGEVYGVVSSNGPVWAEQRKFMHINLNRVGMGKSKKLEQIVEQEVEVMCERVAKLSEVGG-VDFQKLLPVAINNVIWRMITGKTSKQDDPFMLELTDCINRHFETLSPSNPISTLQQYFHRSTKFATDLG-IIEGFQGILKLRDNV-AEQISEFQPDHEG-NFVERYLFEIQS--AHPESSFYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSAK-PSMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGKFVFDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNFKIKPAPGQ 476
             VA  T+I +  V    ++  W  R+  GP P   +P++G+   +  D++P  + +   +YG +F   MG+ P V+I       +       +      +P   YL      G    V++  GP W EQR+F    L   G+GK K LE  V +E   +C+  A  ++ G  ++   +L  A+ NVI  +I  +  + +DP+++ +   +      +S    I  +   F    +     G + +G + +L + +N+  E  + + PD    N  + +L EI+    + ESSF      E+L    ++LF AG  TT+T L+W    +I++P+VQ ++  E+  V+G  + P M  +  +PYT+A I EV R   +   ++PR+T   I +    IPK + ++PN+ ++ +D T +  P  F PE FLD  G FV  E    F  G+R C+GE LA+ E+FLF T ++ +F      GQ
Sbjct:   11 SVAIFTVIFILLVDLMHRHQRWTSRYPPGPVP---WPVLGNLLQVDLDNMPYSLYKLQNRYGDVFSLQMGWKPMVVINGLKAMKEVLLTCGEDTADRPQVPIFEYL--GVKPGSQGVVLAPYGPEWREQRRFSVSTLRNFGLGK-KSLEDWVTKEARHLCD--AFTAQAGQPINPNTMLNNAVCNVIASLIFARRFEYEDPYLIRMQKVLEDSLTEIS--GLIPEVLNMFPILLRIPGLPGKVFQGQKSLLAIVENLLTENRNTWDPDQPPRNLTDAFLAEIEKVKGNAESSF----NDENLRMVVLDLFTAGMVTTSTTLSWALLLMILHPDVQRRVQQEIDAVIGQVRHPEMADQARMPYTNAVIHEVQRFGDIAPLNLPRITSRDIEVQDFLIPKGSILIPNMSSVLKDETVWEKPLRFHPEHFLDAQGHFVKPEAFMPFSAGRRSCLGEPLARMELFLFFTCLLQHFSFSVPNGQ 475          

Query:   35 PSPLLSFPIIGHTWMIGDDIPRYMDRCAEKYGPIFRFDMGYLPTVIIGRYDDYVDACKMEPMNGRAWSIMPFVRYLFGTDSKGEVYGVVSSNGPVWAEQRKFMHINLNRVGMGKSKKLEQIVEQEVEVMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITG---KTSKQDDPFMLELTDCINRHFETLSPSNPISTLQQYFHRSTKFATD-LGIIEGFQGILKLRDNVAEQISEFQ----PDHEGNFVERYLFEIQ--SAHPESSFYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSAK-PSMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGKFVFDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNFKIKPAPGQVYTLKSNPGLAFTS--DPYQAIVESR 500
            P  +  +P++G        +   + +  +KYG I  + +G    V +  +     A      + R         Y F    +G   GVV SNG +W   R+F+   L  +GMGKS+ LE  ++ E   + + + K ++   +   K + +A+ NVIW+++         Q+  +  +L      + +  +  N  + L      +  F  + +G+     G+ +L+D +   I E Q    P +  + ++ YL ++Q     P S+       E +    ++LF AGTETT+T + WT  +L+ YPEVQ KI  E+   +     PS++ +D+L Y  A I EV+R+  +    V   T     L G  +PK T +M +L   +RDP+ +  PNEF PE FLD  GKFV  E +  F  G+R CVGE LA+ E+F+FL+ ++ NF      G+V   + +P     S   PYQ I+  R
Sbjct:   26 PPGIWGWPLVGRMPSRSKHLADQVKQLRKKYGDIITWRIGTRVNVFLCNFKLVKTALSKFECSDRP------DFYTFKLFGEGNDVGVVFSNGVMWQTHRRFILRQLRDLGMGKSR-LEAAIQHEAACLVQELKKHTD-QPMPLPKSINLAVLNVIWKLVADHRYSLQDQEGQYFTQLLTTTTDNMQGFA-LNLFNYLPWLLMITPDFVKNWMGVRVLRDGVCELKDYMKTFIKEHQATLDPSNPKDLLDAYLIDLQERKEDPLSTM----NIETVRAVIMDLFGAGTETTSTMIRWTILYLMKYPEVQAKIQREIDAAVPRGTLPSLEHKDKLAYFEATIHEVHRIVSLVPLGVSHYTNQDTELAGYRLPKGTVVMSHLECCHRDPSYWEKPNEFYPEHFLDDQGKFVKREHLVNFSVGRRVCVGESLARMELFVFLSAILQNFTFSAPKGEVLHTEKDPQQMLFSFPKPYQVIIRER 491          

Query:   34 GPSPLLSFPIIGHTWMIG-DDIPRYMDRCAEKYGPIFRFDMGYLPTVIIGRYDDYVDACK--MEPMNGRAWSIMPFVRYLFGTDSKGEVYGVVSSNGPVWAEQRKFMHINLNRVGMGKSKKLEQIVEQEVEVMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMLELTDCINRHFETLSPSNPISTLQQYFHRSTKFATDLGIIEG-----FQGILKLRDNVAEQISEFQPDHEGN----FVERYLFEIQSA--HPESSFYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSAK-PSMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGKFVFDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNFKIKPA--PGQVYTLKSNPGLAFTSDPYQ 494
            GP+P   FPI+G+   IG  DI +   + +E YGP+F   +G  PTV+I  YD   +A     E  +GR   + P    +    +KG  YG+V SNG  W E R+F  + L   GMGK + +E  V++E   + E + K +     +   +L  A  NVI  +I        D   L L   +N +F+ L+          +      F   +  + G      +  + +R+ V E+I E Q   + N    F++ +L +++    + +S F      E+L     ++F AGTETT+T L +    L+ +PEV  K+  E+  V+G  + P M  R  +PYT A + E+ R   +   +VPR T   +      IPK T ++ +L ++  +   FP+P+ F P  FLD  GKF   +    F  GKR CVGEVLA+ E+FLFLT ++ NF  KP   P  + T     GL      YQ
Sbjct:   32 GPTP---FPILGNILQIGIQDISKSFTKLSEVYGPVFTVYLGMKPTVVIHGYDAVKEALVDLGEEFSGRI--VFPLTAKI----NKG--YGIVFSNGKRWKETRRFSLMTLRDFGMGK-RSIEDRVQEEARCLVEELRK-TNGSPCNPTFILGAAPCNVICSVIFQNRFDYTDQDFLSLMGKLNENFKILN--------SPWVQMCNNFPILIDYLPGSHNKILRNNIYIRNYVLEKIKEHQETLDINNPRDFIDCFLIKMEQEKDNQQSEF----TIENLMTTLSDVFGAGTETTSTTLRYGLLLLMKHPEVIAKVQEEIERVIGRHRSPCMQDRSRMPYTDATVHEIQRYINLIPNNVPRATTCNVKFRSYLIPKGTAVITSLTSMLYNDKEFPNPDRFDPGHFLDASGKFRKSDYFMPFSTGKRVCVGEVLARMELFLFLTAILQNFTPKPLVDPKDIDTTPLVSGLGRVPPLYQ 484          

Query:    4 TVVGVAALTLIGVYAVKYFKKYFWDFRHLNGPSPLLSFPIIGHTWMIGDDIPRY-MDRCAEKYGPIFRFDMGYLPTVIIGRYDDYVDACKMEPMNGRAWSIMPFVRYLFGTDSKGEVYGVVSSNGPVWAEQRKFMHINLNRVGMGKSKKLEQIVEQEVEVMCERVAKLSEVGGVDFQKLLPV--AINNVIWRMITGKTSKQDDPFMLELTDCINRHFETLSPSNPISTLQQYFHRSTKF--ATDLGIIEGFQGI-LKLRDNVAEQISEFQPDHEGNFVERYLFEIQSAHPESSFYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSAK-PSMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGKFVFDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNFKIKPAPGQVYTLK 481
            TV+ +  L L  V  + +   +    R  N P      P++G  + +    P   + +  +KYG +   D   +P+V++       +       N     +    ++LF  +      G++ S+G  W EQR+F  + L   G+GK K LEQ +++E   + E +    + GG+ F     +  A++N+I  +  G+  +  D    E+   ++        S+ +  L   F R  ++   +   +   ++ + L + D +     ++ PD   +F++ +L E+ + +P+ +    +  E+L    ++LF AGTETT+T L W    + +YPEVQEK+  E+  V+G  + P++  RD +PYT+A I EV R+  +  F+VPR       L G  +PK T I+ NL  ++RDP  +  P+ F PE FL+ +G+F   E    F  GKR C+GE LA++E+F+F+T ++  F  KP   +  +L+
Sbjct:   14 TVLHLRILLLAAVTFL-FLADFLKHRRPKNYPPGPWRLPLVGCLFHLDPKQPHLSLQQFVKKYGNVLSLDFANIPSVVVTGMPLIKEIFTQMEHNFLNRPVTLLRKHLFNKN------GLIFSSGQTWKEQRRFALMTLRNFGLGK-KSLEQRIQEEAYHLVEAI---KDEGGLPFDPHFNINKAVSNIICSVTFGERFEYHDSQFQEMLRLLDE--AMCLESSMMCQLYNIFPRILQYLPGSHQTLFSNWRKLKLFISDIIKNHRRDWDPDEPRDFIDAFLKEM-AKYPDKTTTSFN-EENLICSTLDLFFAGTETTSTTLRWALLCMALYPEVQEKMQAEIDRVIGQGRQPNLADRDSMPYTNAVIHEVQRIGNIIPFNVPREVAVDTYLAGFNLPKGTMILTNLTALHRDPKEWATPDTFNPEHFLE-NGQFKKRESFLPFSMGKRACLGEQLARSELFIFITSLIQKFTFKPPVNEKLSLQ 482          

Query:    4 TVVGVAALTLIGVYAVKYFKKYFWDFRHLNGPSPLLSFPIIGHTWMIG-DDIPRYMDRCAEKYGPIFRFDMGYLPTVIIGRYDDYVDACKMEPMNGRAWSIMPFVRYL-FGTDSKGEVYGVVSSNGPVWAEQRKFMHINLNRVGMGKSKKLEQIVEQEVEVMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMLELTDCINRHFETLSPSNPISTLQQYFHRSTKFATD-LGIIEGFQGILKLRDNVAEQISEF------------------QPDHEGNFVERYLFEIQSA--HPESSFYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSAK-PSMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGKFVFDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNFKIKPAPGQ-------VYTLKSNPGLAFTSDPYQAIVESR 500
             VV   A+ L+ V  V   ++  W   +  GP P   FP +G+   +  ++IP    +   +YG +F   M + P V++       +       +     +MP   ++ +G  SKG +   ++  GP W EQR+F    L   G+GK K LEQ V +E   +C+   K +E    +   LL  A++NVI  +I  +  + +DPF        NR          + TL++     T F  + L  I     I  L D    +++ F                  QP  +    + +L E++ A  +PESSF  K+ R       ++LFMAG  TT+T L+W    +I++P+VQ ++  E+  V+G  + P M  +  +PYT+A I EV R   +   ++P +T   I      IPK T ++PNL ++ +D T +  P  F PE FLD  G FV  E    F  G+R C+GE LA+ E+FLF T ++  F      GQ       +YT+   P      +PYQ    +R
Sbjct:   11 AVVIFTAIFLLLVDLVH--RRQRWTACYPPGPVP---FPGLGNLLQVDFENIPYSFYKLQNRYGNVFSLQMAWKPVVVVNGLKAVRELLVTYGEDTSDRPLMPIYNHIGYGHKSKGVI---LAPYGPEWREQRRFSVSTLRDFGLGK-KSLEQWVTEEAGHLCDAFTKEAE-HPFNPSPLLSKAVSNVIASLIYARRFEYEDPF-------FNRM---------LKTLKESLGEDTGFVGEVLNAIPMLLHIPGLPDKAFPKLNSFIALVNKMLIEHDLTWDPAQPPRD--LTDAFLAEVEKAKGNPESSFNDKNLRI----VVIDLFMAGMVTTSTTLSWALLLMILHPDVQRRVHQEIDEVIGHVRHPEMADQARMPYTNAVIHEVQRFADIVPTNLPHMTSRDIKFQDFFIPKGTTLIPNLSSVLKDETVWEKPLRFYPEHFLDAQGHFVKHEAFMPFSAGRRSCLGEPLARMELFLFFTCLLQRFSFSVPDGQPRPSDYGIYTMPVTP------EPYQLCAVAR 500          

Query:   13 LIGVYAVKYFKKYFWDFRHLNGPSPLLSFPIIGHTWMIGDDIPRY-MDRCAEKYGPIFRFDMGYLPTVIIGRYDDYVDACKMEPMNGRAWSIMPFVRYLFGTDSKGEVYGVVSSNGPVWAEQRKFMHINLNRVGMGKSKKLEQIVEQEVEVMCERVAKLSEVGGVDFQKLLPV--AINNVIWRMITGKTSKQDDPFMLELTDCINRHFETLSPSNPISTLQQYFHRSTKFATDLGIIEG-----FQGILKLRDNVAEQI----SEFQPDHEGNFVERYLFEI--QSAHPESSFYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSAK-PSMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGKFVFDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNFKIKPAPGQVYTLKSNPGLAFT 489
            L+G  A      +    R  N P      P +G+ +++  +     +    +KYG +F  ++G +  V+I       +A      N     + P   ++F  +      G++ S+G  W EQR+F    L   G+GK K LE+ +++E + + E +    E  G  F     +  A++N+I  +  G+  +  D +  +L   ++    T   ++    L   F    KF      + G     F    KL+  V+  I     ++ P    +F++ YL E+   + +P SSF+     E+L    ++LF AGTETT+T L W   ++ +YPE+QEK+  E+  V+G  + PS   R+ +PYT+A I EV R+  +   +VPR       L G  +PK T I+ NL  ++RDPT +  P+ F P+ FL+ +G+F   E    F  GKR C+GE LA+ E+F+F T ++  F  +P   +  +LK   G+  +
Sbjct:   22 LLGTVAFLLAADFLKRRRPKNYPPGPWRLPFLGNFFLVDFEQSHLEVQLFVKKYGNLFSLELGDISAVLITGLPLIKEALIHMDQNFGNRPVTPMREHIFKKN------GLIMSSGQAWKEQRRFTLTALRNFGLGK-KSLEERIQEEAQHLTEAI---KEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLDE--VTYLEASKTCQLYNVFPWIMKF------LPGPHQTLFSNWKKLKLFVSHMIDKHRKDWNPAETRDFIDAYLKEMSKHTGNPTSSFH----EENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFLE-NGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSLKFRMGITIS 490          

Query:   13 LIGVYAVKYFKKYFWDFRHL---NGPSPLLSFPIIGHTWMIGD-DIPRYMDRCAEKYGPIFRFDMGYLPT---VIIGRYDDYVDACKMEPMNGRAWSIMPFVRYLFGTDSKGEVYGVVSSNGPVWAEQRKFMHINLNRVGMGKSKKLEQIVEQEVEVMCERVAKLSEVG-GVDFQKLLPVAINNVIWRMITGKTSKQDDPFMLELTDCINRHFETLSPSNPISTLQQYFHRSTKFATDLGIIEGFQGILKLRDNVAEQISEFQPDHEGN-----FVERYLFEIQSAH--PESSFYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSAK-PSMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGKFVFDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNFKIKP 472
            L+ V+ V  F   FW  +     N P     +P++G+  +I D ++   + +  + YGP+F  ++G  P+   VIIG YD   +A K   +  R   I  +  Y+   D      G++ S G  W EQR+F   NL   G GKS  +E +++ EVE + E +   +EVG  V F+     ++ N +W ++ G+    +DP + E+   +N    +   +N I+      H S +++   G  +  +   K+ + +   ISE Q  H+ N     F++  L +I  +   P SSF+G+ G ++L    ++LF+AG ETT+T L W+   L+ +PE+QEK+  E++  +GS + PSMD + ++PYT A +QE+ R + +    + R     + +    +PK T +  +L  I  DP  FP+P  F P RFLD++G+F  +++  +F  GKR C+G+ LA AE+FLFLT +V  F+  P
Sbjct:    4 LLFVFCVVLFLYKFWYLKTKIPPNFPPGPYGWPLVGYYPLIKDSNLSNGLAKLQDIYGPVFSINLG--PSERYVIIGDYDILEEAFKDYTLTPRPSLIQWYNEYIRHGDGYEYSRGLIFSKGEEWKEQRRFTLRNLRDFGFGKSG-MESLIKMEVEELLEIME--TEVGTDVPFKNKFYASVINALWTILNGERVGLNDPTLKEVIHYVN-EIVSQDMNNLINVFPAIRHVSKEWS---GFNKAMKPAFKILEYIKNTISEHQKTHDPNSQARDFIDVVLNKIHESQDDPNSSFHGQLGLQNLEAGVLDLFIAGIETTSTALVWSCLILVTFPEIQEKVYQEIQKNVGSNRLPSMDDKAKMPYTEAVMQEILRFSCIAPLGIFREADRDVKVGDYFLPKGTVVFSHLYAIVNDPKVFPNPERFDPTRFLDENGQFKRNDKNVVFSTGKRDCLGKTLAIAELFLFLTGLVQKFQFLP 470          

Query:    7 GVAALTLIGVYAV----KYFKKYFWDFRHLNG----PSPLLSFPIIGHTWMI-GDDIPRYMDRCAEKYGPIFRFDMGYLPTVIIGRYDDYVDACKMEPMNGRAWSIMPFVRYLFGT-DSKGEVYGVVSSNGPVWAEQRKFMHINLNRVGMGKSKKLEQIVEQEVEVMCERVAKLSEVGGV----DFQKLLPVAINNVIWRMITGKTSKQDDPFMLELTDCINRHFETLSPSNPISTLQQYFHRSTKFATDLGIIEGFQGILKLRDNVAEQISEFQPDHEGNFVERYLFEIQ-SAHPESSFYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSAKPSMDRRDELPYTHAAIQEVYRLN---PMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDG-KFVFDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNFKIKP--APGQVYTLKSNPGLAFTSDPYQAIVESR 500
             +A + L+G++ V    K FK Y    +   G    P P  S P+IGH ++   + I  +M+  A++ G IF FD G   TVI+   D    A K++ +  R    M     + G  +  G + G+  ++G  W +QRKF    L  +G G++  +E+++  E + M +++ + S+ G V    D    +  A+N V+W  ++G   +  D  +      + +HF T+      S + +  H           + G        +N A + S F P+   +F++ YL +IQ +  P SSF+ + G  ++     +LF+AG +TTAT L+W   +++ +PE+Q K+  E+  V+G+  PS++ R + PY  A + E+ RL    P G    PR TL  + L    IPK+T ++  ++ +  +P  FP+PN F+PERFL  DG KF+ DERV+ FG GKRKC GE +A+ E++LF   ++ NFK +    P ++  ++ + GL     P    +E R
Sbjct:    8 SLAKMLLLGIFFVLIVYKVFKSYHGYPKVYMGQPLPPGPNWSLPLIGHLYLFKANPIETFME-MAKQLGGIFMFDFGPKTTVILLDPDLIDQAMKIDALPSRPLKEMESQALIRGERNPDGSLPGIAFADGTSWKDQRKFAFSQLISLGFGRNVDIEEVIRSECDAMVQKLKQTSKDGTVPVIIDTNNFIGNALN-VVWHFVSGNPVRMSDELLR-----VPQHFATI-----FSNIDEAHH-----------VPG-------SENDAHKKS-FDPNLVRDFIDAYLKKIQDTKDPTSSFHEQRGEVNMRNSMFDLFIAGMDTTATTLSWGLIYMMKWPEIQVKVQEEIARVIGNDTPSLNHRSKTPYVEATLLEIQRLACIVPWG----PRATLDDVQLGPYVIPKNTHVLYIIQNLTHNPKFFPEPNHFKPERFLSDDGTKFIRDERVATFGLGKRKCPGENMARMELYLFFVTLLKNFKFRSDVNPREI-NIEGDLGLVLEPKPCSTRLEIR 486          

Query:   41 FPIIGHTWMIGDDIPRYMDRCAEKYGPIFRFDMGYLPTVIIGRYDDYVDACKMEPMNGRAWSIMPFVRYLFGTDSKGEVYGVVSSNGPVWAEQRKFMHINLNRVGMGKSKKLEQIVEQEVEVMCERVAKLSEVGG-VDFQKLLPVAINNVIWRMITGKTSKQDDPFMLELTDCINRHFETLSPSNPISTLQQYFHR---STKFATDLGIIEGFQGILKLRDNVAEQIS----EFQPDHEGNFVERYLFEI-QSAHPESSFYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSAKPSMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGKFVFDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNF---KIKPAPGQVYTLKSNPGLAFTSD--PYQAIVESR 500
             P+IG+   +G D+    +   EKYG I  F +G   +V+I  +D   +  K +  +GR  ++       FG   +    G+V S+G  W EQRKF    L   G+GKS  L+ ++  EV+ + + +   ++ G  +D +    +AI N +W+++ G+ S  ++P M  +         + S S P+  +    H    ++KF       E  +   ++R+  +E I      +Q +H+ +F++ Y+ ++ ++    SSFY + G  +L    ++LF AG+ETTAT L + F +LI +P +Q+KI  E+  V+GS  P ++ R E+PYT A + EV R + +  ++ P  T  Q+NL+G  +PK T +  N+  I  DP  +  P EF P RF+D+ GKF  ++R   F  GKR C+G+ LA+ E+FLFLT ++       I   PG V     NP + F      +Q +++ R
Sbjct:   34 LPVIGNVLSVGYDLKSAFNTWREKYGSIVGFKLGNQTSVVISDFDTLNEVFKDDRYSGRPENLQEVFSAFFGKGKEKSTGGIVFSHGDHWKEQRKFASRTLKDFGVGKSG-LQTLINDEVKKLIDELQ--NDTGKPIDLRLRTNLAIVNTLWQVLNGEKSDLNNPKMKRVFKSTTEFIVSNSLSGPVMIMPWLRHLPYFNSKFE------EARKSPQEMREITSESIQRHKDSYQEEHQRDFIDCYIKKMNETEESGSSFYNETGEGNLQRTLMDLFGAGSETTATILCFAFNYLIRFPSIQQKIQEEIELVIGSRTPLLEDRQEMPYTDAFLHEVLRHSCI-VYTTPHATTEQVNLHGYTLPKGTAVYANIWWIMNDPEHWDKPEEFNPLRFMDEAGKFKKNDRFIPFLIGKRYCLGQNLAQHELFLFLTGLLQKLSFSSIYEDPGMVNI---NPIVGFMHQCPEFQVVMKER 494          

Query:   30 RHLNGPSPLLSFPIIGHTWMIGDDIPRYMDRCAEKYGPIFRFDMGYLP-TVIIGRYDDYVDACKMEPMNGRAWSIMPFVRYLFGTDSKGEVYGVVSSNGPVWAEQRKFMHINLNRVGMGKSKKLEQIVEQEVEVMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMLELTDCINRHFETLSPSNPISTLQQYFHRSTKFATDLGIIEGFQGILKLR-------DNVAEQISE----FQPDHEGNFVERYLFEIQ-SAHPESSFYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSAKP-SMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGK-FVFDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNFKIKPAPGQVYTLKSNPGLAFT--SDPYQAIVESR 500
            R +N P P  + P +G    I   +   + + ++KYGP+ +F +G  P TV+I       +   ++P  GRA ++  F  +      +GE  G++++ G +WA+QR+F    L   G GKS  +E ++ +EV  M +R+         D + +L +A+ N +W ++ G    QDDP + EL   I   F+  + +  +  L  +            II G  G   +R       D V++ I E     Q +   +F++ YL EI+ +A   SSF+G++    L     +LF AGT++ ++ L W   +L+  PEVQ K+  E++ V G+++P S   R ++PY+ A I EV R      F VP   L      G+  PK T IM NL  I+ DP  + DP  FRPERFL  D K     E ++ F  G+R+C GE LAK  IFLFLT++V  F I   P         P ++F   S PYQ + + R
Sbjct:   25 RTINLPGPW-ALPFVGSMLEIEPRMYLTLHKWSKKYGPMCKFQIGAGPSTVLIADPIIAKEMLSLDPFVGRA-TVKEFTLF------EGENIGLINAEGKIWADQRRFTVRQLRDFGFGKSS-MESMIMEEVNEMKDRLLAYKGRPIDDIKNMLSLAMLNSLWSIVAGTRYSQDDPKLRELARQITGAFDEAAKAGAVLVLAPWLKH---------IIPGLIGYTSIRRTMRGLVDFVSKTIKEHKETVQEESPRDFIDVYLNEIKRTADVTSSFHGENAERQLIAAVADLFQAGTDSMSSTLNWALLYLLKLPEVQRKLQAEIKAVTGNSRPVSFSDRPKMPYSLAVINEVLR-KAAPPFGVPHRVLVDTEYKGVFFPKDTGIMINLYYIHSDPKLWGDPENFRPERFLTSDEKGLEKTENLNPFLIGRRQCPGETLAKDTIFLFLTNLVQKFNILADPNSPEP-DLEPAVSFIVQSKPYQVVFQER 492          

Query:   34 GPS--PLL-SFPIIGHTWMIGD--DIPRYMDRCAEKYGPIFRFDMGYLPTVIIGRYDDYVDACKMEPMNGRAWSIMPFVRYLFGTDSKGEVYGVVSSNGPVWAEQRKFMHINLNRVGMGKSKKLEQIVEQEVEVMCERVAKLSEVGG-VDFQKLLPVAINNVIWRMITGKTSKQDDPFMLELTDCINRHFETLSPSNPIS----TLQQYFHRSTKFATDLGIIEGFQGILKLRDNVAEQISEFQPDHEGN-FVERYLFEIQS-AHPESSFYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLG-SAKPSMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGKFVF--DERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNFKIKPAPGQVY------TLKSNPGLAFTSDPYQAIVESR 500
            GPS  P+L S P +   +  G    IP+  +  A+ YGPI R  +G LPT++I   D   +A K + +  R   + PF  + +GT+  G+  GV+ S+G  W EQR+F    L   G G+S  +E +++ EV+ +   +    E G  +D    + ++I N +W ++ G+  + DD  +L++   +++       S  +S    TL +YFH   +FA      E  + ++     + +    F PD   N F+E YL EIQS + P+SSFY   G + L    ++LFM G+ETT+  L WTF  L+ +P+VQ++I  EL  ++G  + P +     LPY  A + E  R++ +    VP        + G  +PK + +M N+ + + +P  + DP EF P+RFLD DGKF      + + F  GKR C+G+ LA+ E +LFL  ++  FKI     Q           +N G    +  Y+ I+ESR
Sbjct:   29 GPSSVPILGSIPFVPKRFRHGGRLHIPKLFNYLAQTYGPISRVYLGPLPTIVISDLDLVKEAFKKDEITSRP-PMRPFHEFRYGTEDGGQ-RGVILSSGKEWQEQRRFSMRQLKDFGFGRSS-MEDMIQVEVQKLVNSLHM--ETGQPLDLNFKMNISIVNALWVILVGERLELDDARLLDIVKTLDKLLRGAQVSGLLSVLFPTLYKYFH--PRFALAKNTFESMRSLMT--QAIEDHRQRFNPDEAPNDFIECYLQEIQSTSDPQSSFYQDQGLKSLDCVLIDLFMGGSETTSITLVWTFLCLLHHPDVQDRIHQELDSIIGPDSVPQLQDLPTLPYLRAVMTETLRVSSVVPNGVPHYVTVSTKVGGYLLPKGSAVMANIISPHLNPKVYEDPEEFNPQRFLDPDGKFQMPNSSQFAPFSLGKRFCLGQTLAEQEYYLFLAGILQKFKIHNPQEQTLPNYRFSADDANTGFVRYAPKYEVILESR 507          

Query:    8 VAALTLIGVYAVKYFKKYFWDFRHLNGPSPLLSFPIIGHTWMIGDDIPRYMDRCAEKYGPIFRFDMGYLPTVIIGRYDDYVDACKMEPMNGRAWSIMPFVRYLFGT---DSKGEVYGVVSSNGPVWAEQRKFMHINLNRVGMGKSKKLEQIVEQEVEVMCERVAKLSEVGG-VDFQKLLPVAINNVIWRMITGKTSKQDDPFMLELTDCINRHFETLSPSNPISTLQQYFHRSTKFATDLGIIEGFQGILKL-RDNVAEQISEFQPDHEGNFVERYLFEIQSAHPESSFY--GKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSAK-PSMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGKFVFDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNF-----KIKPAPGQVYTLKSNPGLAFTSDPYQAIVESR 500
            V  L  +G + + Y+KK F   R  N P    ++PI+G    IG ++   M+R   +YG IF   MG   TV+I  YD        E +N   + I P ++ L      D  G+V GV+ SNG  W E ++F   +L   G G+   +E ++ ++   +     +  +VG  V     L + I N +W +I+G+    +D  +L++   ++    T+  S+ I+      +   +       I  + GI KL        +  FQ  H  +F++ Y+ E++S +  S  Y  G+ G E++     +LF+AG++TT   L WT  +L      Q ++  E+  V+G  + PS+  + +LPY  A +QEV+R++ +G+  VPR+T     L G  IPK T+I  ++  I  D   + +P+EF PERFLD++GKF  DER   FG GKR+C+G+ LA+ E+FLF+  +   F     K KP P     L+  PG      PY  ++  R
Sbjct:    3 VLILLFLGAFCL-YYKKNF--VRPPNFPPGPFNYPILGGIPAIGQNVLTGMNRLQSQYGKIFSVYMGTDRTVVIADYD-----LAKEALNKDEFCIRPDIKALNDIRYPDENGQVRGVMFSNGDEWLEVKRFALRHLRDFGFGRIG-MEALIWKKYNGVSSFFKE--DVGKEVCLNLKLNIPILNALWHIISGEKLDYNDEHLLDIVHKVDVMMTTIDVSSVINLFPWLKYICPEATGYSKTINAYLGIRKLIEQQYHTHLETFQEGHMRDFMDVYIQEMKSQNQNSKSYLHGQRGLENMNSLLSDLFVAGSDTTTNTLNWTIFYLAKDVAKQRRLQNEIDTVIGQDREPSLQDKPDLPYLEAIVQEVHRISALGYLGVPRITGKDTQLGGYDIPKGTRIFTHIYHIMHDKDYWTNPDEFMPERFLDKNGKFQMDERSIPFGIGKRQCLGKTLAQNELFLFIAGLFQTFNFNFPKDKPVP----NLEPIPGFVLACPPYNVVMSLR 493          

Query:   30 RHLNGPSPLLSFPIIGHTWMIGDDIPRYMDRCAEKYGPIFRFDMGYLPTVIIGRYDDYVDACKMEPMNGRAWSIMPFVRYLFGTDSKGEVYGVVSSNGPVWAEQRKFMHINLNRVGMGKSKKLEQIVEQEVEVMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMLELTDCINRHFETLSPSNPISTLQQYF-HRSTKFATDLGIIEGFQGILKLRDNVAEQISE--------FQPDHEGNFVERYLFEIQSA-HPESSFYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSAKP-SMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGK-FVFDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNFKIKPAPGQVYTLKSNPGLAFTSDPYQAIVESR 500
            R +N P P    PI+G+ + IG  +   M +   KYGP+ +  +G +  V+I       +   M+   GR  +   FV Y      +GE  G++ S G +W +QR+F+   L   G GKS  +E I+ +EV  + ER+A        + +  L +A  N +W ++ G    QDDP +  L   ++  F     +     L ++  H + +F        G+ GI ++  ++AE +S+        FQ D   +F++ YL EI+S   P SSF+G +              AG +T A+ L W    +I  PE+  K+  E++ V G+++P S   R ++PYT A I E+ RL  +  F VP   L+     G+ +PK T IM NL  ++ DP  + DP  FRPERFL  + K  V +E ++ F  G+R+C GE LA+  IFLFL ++V  F I   P     L+   G      PY+A+   R
Sbjct:   25 RTINLPGPW-GLPIVGNAFQIGKRMHITMAKWGMKYGPMCKVKLGPMEVVVISDQHVAKEMLAMDAFVGRT-TPPEFVLY------EGETVGIIGSEGELWEQQRRFVVRQLRDFGFGKSS-MESIIMEEVNELGERLAAFKGEPITNMKSFLSLATVNSLWSIVAGTRYSQDDPKLRALAHRLSGAFNDAGENAGALFLMKWLKHIAPEFC-------GYNGIRRMFADLAEFVSKTIQEHKNTFQEDSPRDFIDVYLKEIKSTTDPSSSFHGAEA-------------AGADTMASTLNWAILHIINNPEILRKLQAEIKEVTGNSRPVSFSDRPKMPYTLAMINEMLRLT-LSPFGVPHCVLNDTEYKGVFLPKGTIIMINLHFLHHDPRVWGDPENFRPERFLTPNEKSLVKNEYLNPFMVGRRQCPGESLARDTIFLFLVNLVQKFDILKEPSSEVDLEPEIGFLLQPKPYKAVFLER 477          

Query:   41 FPIIGHTWMIGDDIPRYMDRCAEKYGPIFRFDMGYLPTVIIGRYDDYVDACKMEPMNGRAWSIMPFVRYLFGTDSKGEVYGVVSSNGPVWAEQRKFMHINLNRVGMGKSKKLEQIVEQEVEVMCERVAKLSEVGG-VDFQKLLPVAINNVIWRMITGKTSKQDDPFMLELTDCINRHFETLSPSNPISTLQQYFHR---STKFATDLGIIEGFQGILKLRDNVAEQIS----EFQPDHEGNFVERYLFEI-QSAHPESSFYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSAKPSMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGKFVFDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNF---KIKPAPGQVYTLKSNPGLAFTSD--PYQAIVESR 500
             P+IG+   +G D+    +   EKYG I  F +G   +V+I  +D   +  K +  +GR  ++       FG   +    G+V S+G  W EQRKF    L   G+GKS  L+ ++  EV+ + + +   ++ G  +D +    +AI N +W+++ G+ S  ++P M  +         + S S P+  +    H    ++KF       E  +   ++R+  +E I      +Q +H+ +F++ Y+ ++ ++    SSFY +    +L    ++LF AG+ETTAT L + F +LI +P +Q+KI  E+  V+GS  P ++ R E+PYT A + EV R + +  ++ P  T  Q+NL+G  +PK T +  N+  I  DP  +  P EF P RF+D+ GKF  ++R   F  GKR C+G+ LA+ E+FLFLT ++       I   PG V     NP + F      +Q +++ R
Sbjct:   34 LPVIGNVLSVGYDLKSAFNTWREKYGSIVGFKLGNQTSVVISDFDTLNEVFKDDRYSGRPENLQEVFSAFFGKGKEKSTGGIVFSHGDHWKEQRKFASRTLKDFGVGKSG-LQTLINDEVKKLIDELQ--NDTGKPIDLRLRTNLAIVNTLWQVLNGEKSDLNNPKMKRVFKSTTEFIVSNSLSGPVMIMPWLRHLPYFNSKFE------EARKSPQEMREITSESIQRHKDSYQEEHQRDFIDCYIKKMNETEESGSSFYNETVEGNLQRTLMDLFGAGSETTATILCFAFNYLIRFPSIQQKIQEEIELVIGSRTPLLEDRQEMPYTDAFLHEVLRHSCI-VYTTPHATTEQVNLHGYTLPKGTAVYANIWWIMNDPEHWDKPEEFNPLRFMDEAGKFKKNDRFIPFLIGKRYCLGQNLAQHELFLFLTGLLQKLSFSSIYEDPGMV---NINPIVGFMHQCPEFQVVMKER 494          

Query:   33 NGPSPLLSFPIIGHTWMIGDDIPRYMDRC--AEKYGPIFRFDMGYLPTVIIGRYDDYVDACKMEPMNGRAWSIMPFVRYLFGTDSKGEVYGVVSSNGPVWAEQRKFMHINLNRVGMGKSKKLEQIVEQEVEVMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMLELTDCINRHFETLSPSNPI----STLQQYFHRSTKFATDLGIIEGFQGILKLRDNVAEQISEFQPDHEGNFVERYLFEIQ-SAHPESSFYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSAKP-SMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGKFVFDERVSL--FGKGKRKCVGEVLAKAEIFLFLTHMVHNFKIK---PAPGQVYTLKSNPGLAFTSDPYQAIVESR 500
            N P      PI+G+ + +  ++  ++  C  A+KYGPI R D+    TV++  Y    +       +GR    M F  + F    +  ++G+V++ G  W E R+F    L   G G++  +E+ +  EV  + E + ++      + ++ L  A+ N +W + TG+  K +D  +LE+T+   + F+++    P+      L + F   + +      ++GF      R  V + +  F PD + +F + ++ EI+ + + ES+FYGK G ++L     +L+ AGT+TT+T L+W   +L   PE+Q+K   E+  + G+ KP S+  R  +P+T A I E  R + +    V    L  I   G  IPK+T I  NL  I+ DP  + DP  FRPERFL  DGK VF +  +L  F  G+R+C+GE LA+  +FLF T++   F +K     P   +  K++     T  PY  I + R
Sbjct:   29 NSPPGPFRIPILGNIFQV--ELLAHLSFCKWADKYGPIIRVDLATTKTVVVSDYKMVKELFNDPASSGR----MDFSMFDFVLSDR--LHGIVNTEGQDWEELRRFTLRQLRDFGFGRNT-MEESIMLEVTELIEWLKEVENKPVENVKEKLTFAVINSVWSICTGERYKHNDAAILEMTERALKTFDSVMERGPLLLFAPILGKLFPVLSGYTLVREAVDGFADYF--RKPVNQHLKTFSPDFDRDFADVFIKEIKKTTNTESAFYGKFGEDNLLATLGDLYFAGTDTTSTTLSWMILYLSKMPEIQKKFQDEIESITGNTKPVSISDRANMPFTEALIAETLRFSSITPSGVQHKALRDITFRGYTIPKNTVITSNLYYIHHDPKVWGDPENFRPERFLSPDGK-VFKKHEALMPFSTGRRQCIGESLARDSLFLFATNVFQRFWVKFDENGPQNGFDSKASFTFIITPKPYSVIFKDR 497          

Query:   63 EKYGPIFRFDMGYLPTVIIGRYDDYVDACKMEPMNGRAWSIMPFVRYLFGTDSKGEVYGVVSSNGPVWAEQRKFMHINLNRVGMGKSKKLEQIVEQEVEVMCERVAKLSEVGG-VDFQKLLPVAINNVIWRMITGKTSKQDDPFMLELTDCINRHFETLSPSNPISTLQQ-YFHRSTKFATDLGIIEGFQGILKLRDNVAEQISE--------FQPDHEGNFVERYLFEI--QSAHPESSFYGKDGREHLFGQAVNLFMAGTETTATFLTWTFKFLIMYPEVQEKISIELRHVLGSA-KPSMDRRDELPYTHAAIQEVYRLNPMGFFSVPRLTLSQINLNGIPIPKHTQIMPNLRTINRDPTSFPDPNEFRPERFLDQDGK-FVFDERVSLFGKGKRKCVGEVLAKAEIFLFLTHMVHNFKIKPAPG 475
            E +GPI    +G  P VI+  +D   D  K    +GR  +  PF    FG+   G   G++ S+G  W EQR+F    L  +G GKS  +E ++ +EV  + + + K  +VG  +     L ++I N +W ++TG+    +DP +  +    +        + P S L + +  +  KF +      GF+ +  L  ++ + + +        + PDH  +F++ YL EI   S  P+SSF+G  G E L    ++LF+AGTETT++ L W+  FL+ +PEVQ ++  E+  V+G   + S++ R  LPYT+A + E  R+  +   ++P      I LNG  IPK + I+ NL  ++ DPT +P+P+EF P RF D+  + F  +ER+  F  GKR C+G+ LA+ E FLF T ++  F  +PAPG
Sbjct:   62 ETFGPISGLYLGKRPMVILSDFDLIKDLYKKHEASGRPKN-KPFHENRFGS-PDGSQRGLLQSSGQEWQEQRRFTMKQLKDLGFGKSS-MEDMINEEVAKLAQLLEK--DVGKEMSMNLKLNLSIVNALWYLLTGEHFALEDPELQAIVAKFDSLLRLEIKNTPFSILMEGWMPKLAKFTS-----PGFKHMKDLFTDIKDLVGKALVDHKKTYDPDHPRDFMDMYLAEIDKSSNAPDSSFHGTRGEESLVSTMLDLFLAGTETTSSSLLWSILFLLHHPEVQARVQREIDEVVGVGNQVSLEDRALLPYTNAVLMESMRMATIVPSALPHAATEDIQLNGYVIPKDSVILANLLHVHYDPTYWPNPDEFNPNRFYDEATRTFKQNERLIPFSIGKRYCLGQSLAEKEYFLFFTGLLQRFTFEPAPG 478