Query:    7 VTILALFGVYAVKYIKKYFWDLRHLKGPSPFLSFPIIGHAWMIGDDIPRYMDQCAEKYGPIFRFDMGYLPTVIIGRHEELVEACKMEPMNGRSWGIMPFVRYLFGTDSKGEIYGVAISNGRVWVEQRKFTHTNLN--------RVGMGKARELEQIVEQEVQVMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMQELAECINRHFETLSPNN------LISTLQQYFHRCTKYATDWGIIKGFKDILKLRANVAKEISEFQPDQEGNFVERFLFEIESAHPESSFYGEDGRNHLFGQAVDLFVAGTETTSTFLTWTFKFLIMYPEVQEKISIELRHVFGSAK-PSLDRRDELPYTNATIQEICRLNPMSVFSIPRLTMSQINLNGIPIPKHTQVMPNLRTINRDPRSFPDPDEFRPERFLDEDGKFVFNERVVLFGRGKRKCVGQVLAMAEIFLFLAHMVHTFKIKPAPGQVY-TLKSNPGLAFTSYPYLSVVELR 499
            V I  L  +Y +K++KK F DL     P P + +PI+G   +I  +    +   A K+G I    MG    V++  ++ + +A   +  + R    +     L G       YG+  S G +W  QRK+    LN        + G G   ++E +V +EVQ     +        V+   L   A++NVI  +I  +  +  DP  Q      +  F   +          +  L      CTK   +   +  F     +R  +++   E  P    + ++ +L  ++ + P+  F   D    L    +DLF A  ETT T L W   F++  P++  K+  EL  V G    P L    +LPYT AT+ EI R + +        T  ++   G  +P+++ V+P +  ++ +P+++ +P+EFRPERF++++G     E  + FG G+RKC+G  LA  E FLF   +VH F +   P Q   +L+   G+  T   +   ++LR
Sbjct:   17 VLIAFLTLLYILKHLKKSFKDL----PPGP-IGYPIVGIIPLIKKEFHLLLFDYAMKFGKIVSLKMGGETVVVLSDYQTIKKAFSCKYFSARPKTEL---SQLLGG------YGIVNSEGPLWKTQRKYL---LNQKLGMKHWKSGAGSLEQIESVVSREVQSFLYTLENDYSNTFVNLTPLFNCAVSNVICSIIXSRRFRYQDPKFQRFMFLFDEGFRLFTMTGAMTFLPFLKVLPGISDTCTKLRQNREEMIAF-----VREIISEHRQELDPQNPKDLIDSYL--VQESTPDQFFEDYDPEQQLEQIILDLFSASVETTRTSLLWAIVFMLHNPKILSKVRDELNSVVGEDNLPQLSDMIKLPYTRATLYEIMRRSSVVPMGTTHATDREVQFEGFVLPQNSHVIPLIHAVHMNPKNWENPEEFRPERFINKEGVLFKPEHFMPFGVGQRKCLGDRLAEQEFFLFFTSLVHVFDLGNNPEQTMPSLRGTAGVTVTPSEFSVHIKLR 501          

Query:   29 RHLKGPSPFLSFPIIGH-AWMIGDDIPRYMDQCAEKYGPIFRFDMGYLPTVIIGRHEELVEACKMEPMNGR--SWGIMPFVRYLFGTDSKGEIYGVAISNGRVWVEQRKFTHTNLNRVGMGKARELEQIVEQEVQVMCERVAKLSEV--GGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMQELAECINRHF-ETLSPNNLISTLQQYFHRCTKYATDWGIIKGFKDILKLRANVAKEISEFQPDQEGNFVERFLFEIESAHPESSFYGEDGRNHLFGQAVDLFVAGTETTSTFLTWTFKFLIMYPEVQEKISIELRHVFGSAKPSLDRRDELPYTNATIQEICRLNPMSVFSIPRLTMSQINLNGIPIPKHTQVMPNLRTINRDPRSFPDPDEFRPERFLDEDGKFVFNERVVLFGRGKRKCVGQVLAMAEIFLFLAHMVHTFKI 469
            R  K P    + PI+G   +M G       D    KYG ++   +G +  V+I  ++   +    E ++ R  +W       +       G   G+  ++G VW EQR+F   NL   G GK   L+ +++ E +   E + K S+   G +  +    V I N++W++I G    +D+   +E+   ++  + E  S  + I    ++F +  K   D    K F      R+ + + + ++      +F++ ++ E+     E+ F+ E     L    +D F AG ET++T L W+  ++ +YPE Q K   E+  V G   PS +   ++ Y NAT+ EI R+  +   ++P +T+  + ++G  IP+ T++  N+   + +P+ FP P  FRPERF+ E+GK    E    FG GKR C+G+ +A  ++F+F   M+   KI
Sbjct:   22 RKSKFPPGPPNLPIVGTLPYMNGIGSNALTDPKFGKYGDLYSLFIGNIHLVVINNYQLAKDLFAREDVSYRRETW-------WTLNVRGDGHPLGIINTSGHVWKEQRRFAVRNLKDFGFGK-NTLDAVIQNEARFTIEDIIKESKNNNGVLRMESTFNVGIINILWQIIAGYRFDKDNEKTKEMMGHLHEVYSEGYSILHYIPA-ARFFIKRDKRMDDMLRTKEF-----FRSQIREHMKDYDASNPRDFIDVYIKEMLDEDREN-FHEE----QLMTTCLDFFQAGGETSATTLLWSVLYISLYPEAQAKCVEEIEAVLGKEDPSQEVYKDMVYCNATLMEIQRMASVGPLTLPHVTIKDLFIDGYCIPRGTEIYGNIIAFHNNPKFFPSPKSFRPERFI-ENGKLKKLEAFAPFGVGKRICMGESMAKNQLFIFFVMMLQKLKI 448          

Query:    1 MSSTVGVTILALFG--VYAVKYIKKYFWDLRHLKGPSPFLSFPIIGHAWMI---GDDIPRYMDQCAEKY--GPIFRFDMGY-LPTVIIGRHEELVEACKMEPMNGRSWGIMPFVRYLFGTDSKGEIY-GVAI-----SNGRVWVEQRKFTHTNLNRVGMGKARELEQIVEQEVQVMCERVAK--LSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMQELAECINRHFETLSPNNLISTLQQYFHRCTKYATDWGIIKGFKDILKLRANVA-----------KEISEFQPDQEGNFVERFLFEIESA--HPE---SSFYGEDGRNHLFGQAVDLFVAGTETTSTFLTWTFKFLIMYPEVQEKISIELRHVFGSA------KPSLDRRDELPYTNATIQEICRLNPMSVFSIPRLTMS-QINLNGIPIPKHTQVMPNLRTINRDPRSF-PDPDEFRPERFLD--EDG--KFVFNERVVLFGRGKRKCVGQVLAMAEIFLFLAHMVHTFKIKPAPGQVYTLKSNPGLAFTSYPY 492
            MS  + +T+  +    +Y +K      W       P+P    P+ GH+  +   G +     D+  +++  G +    +   +   +I   + L +  K + +N R       + + F  D   ++Y G+ +     S G +W +QR+F  + L   G G++  +E ++ +E  +    + +  +   G +    L  + I NV+WR++ G   +  DP   EL + +++  + +   NL  T+   F           I  G  D  ++ + VA              + F P+   +F++ +L +I+ +  +P+    SF GE G+ +L    +DLF AG+ETTS+ L+W   F++ +PE+Q+K+  EL             K   + R  LPYT A I EI R   ++   +P  T S    +    +PK   V   L  I R+P+ F P+PD+F P+RFL+   DG  KF+ NE ++ F  GKR C G+ LA  EIF F   ++  F+++   G++ +     G+     P+
Sbjct:    1 MSVALVITVCLILAXILYEIK------WKYPENYPPTPPFRLPLFGHSLYLRSAGKNFQEGFDRIFDRFNVGGVLCLQVAARIRMXMISDFDILKKILKTDDLNYR-------LAHDFSIDYTKKLYQGIGVDGXLWSYGXIWKQQRRFMLSTLKNFGFGRS-SMEDMLMEEATLFVNFLNEENIQTGGNIRIANLFNIGILNVLWRIVAGTRFEYRDP---ELQKIVHKVGDAILSTNLKPTIAAIFPFLRT------IYPGIDDXQEVTSKVAAVYEFLQTAVKNHEANFDPNHPRDFIDTYLLKIKDSEENPDKENDSFRGELGKLNLSKTLLDLFFAGSETTSSTLSWGVLFMVRHPEIQKKVQEELDLFLHEGDGESFRKARSEDRIHLPYTEAXICEIQRRGNITPMGVPHATYSGDAKVGDYVVPKGHVVNAYLSGIFRNPKYFGPNPDQFNPDRFLEVASDGGVKFIKNEYLIPFSIGKRSCPGENLARMEIFSFFTSILQRFELRSIDGEIPSTDFISGITSIPKPF 513          

Query:  116 GEIYGVAISNGRVWVEQRKFTHTNLNRVGMGKARELEQIVEQEVQVMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMQELAECINRHFETLSPNNLISTLQQYFHRCTKYATDWGIIKGFKDILKLRANVAKEISEFQPDQEGN----FVERFLFEIESAHPESSFYGEDGRNHLFGQAVDLFVAGTETTSTFLTWTFKFLIMYPEVQEKISIELRHVFGSAKPSLDRRDELPYTNATIQEICRLNPMSVFSIPRLTMSQINLNGIPIPKHTQVMPNLRTINRDPRSFPDPDEFRPERFLDEDGKFVFNERVVLFGRGKRKCVGQVLAMAEIFLFLAHMVHTFKIK 470
            G  YG+A S G +W  QR+F+   L  +G GK      I EQ + +      +      +  + +  + + NV+W+++  K+    +   +++   +N  F      N    L+++ H       D       K  LKLR  + + I E   + + N    F++ +L E++  + +S+F     +  L    +DLF+AG ETT+T L W   ++ +Y  VQEK + E+  V GS  P  +    LPYT AT+ EI RL   +  S+P   +  I +    +PK T  + NL   + DP  F +P +F P+R+L         ++ V FG GKR C+G  LA  E++ F   ++  F I+
Sbjct:   12 GIAYGIASSEGILWQNQRRFSLMKLKNLGFGKKSIEIIIYEQIINLFEMIETQKDSFNDLFIKDIFTIPVVNVLWKIVASKSYDWRNSGERKVXAAVNEVFGAAYETNFF--LEKFRHFLPYDIAD-------KSTLKLRQIMEELIDEHTQNLDENSPNDFMDVYLIEMKK-NVDSTF----SKKQLASLCIDLFLAGAETTNTTLVWALLYMSLYEGVQEKCAEEINSVLGSRMPQEEDMKNLPYTIATLNEIQRLCNTAPASLPHKNLKDIKIGDYVVPKGTLFLANLIGFHHDPNIFENPQQFNPDRWLHYKS---CPQQFVPFGFGKRICMGVSLAKKELYYFFVMLIKMFIIR 353          

Query:   17 AVKYIKKYFWDLRHLKGPSPFLSFPIIGH-AWMIGDDIPRYMDQCAEKYGPIFRFDMGYLPTVIIGRHEELVEACKMEPMNGRS---WGIMPFVRYLFGTDSKGEIYGVAISNGRVWVEQRKFTHTNLNRVGMGKARELEQIVEQEVQVMCERVAKLSEV--GGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMQELAECINRHFETLSPNNLISTLQQYFHRCTKYATDWGIIKGFKDILKLRANVAKEISEFQPDQEGNFVERFLFEIESAHPESSFYGEDGRNHLFGQAVDLFVAGTETTSTFLTWTFKFLIMYPEVQEKISIELRHVFGSAKPSLDRRDELPYTNATIQEICRLNPMSVFSIPRLTMSQINLNGIPIPKHTQVMPNLRTINRDPRSFPDPDEFRPERFLDEDGKFV-FNERVVLFGRGKRKCVGQVLAMAEIFLFLAHMVHTFKIKPAPGQVYTLKSNPGLAFTSYPYLSVVELR 499
            A+ Y K+  W  R   GP    + P++G   +M G      ++    K+G ++   +G +P ++I   +   E    E ++ R    W I   VR     D K  + G+  + G  W  QR+F    L   G GK R L+ ++++E Q   + + + S    G V       V+I NV+W+++ G+    ++   +E  E +N  F           + +YF +  +       +K F      R  + + I +   D   +F++ +L E+  +  + S++  +                               ++  + +E+I  +L+   G  KP+ D   ELPYT+AT+ E+ RL  +   S+PR T   I++NG  IP+ T++  N    +RDP  FP+P EF+PERFL EDG  V  +E  + FG G+R C+G+ LA  ++ +F   ++    I    GQ      +  +  T  P    V++R
Sbjct:    2 ALGYFKRKRWVARFPPGPR---NLPLVGSIPFMNGIGTQGCLNPDYRKFGDLYTLFIGPIPLIVINSFQLTKELYVKEEISSRRDTWWTIN--VR----GDGKQSL-GIINTGGMKWQTQRRFALRQLREFGFGK-RSLDSVIQEEAQASIDTILQESSKNDGKVLMASNFNVSIINVLWQIVAGQRFDPEESSTKERMEHLNEVFRVGYSVLHYLPIARYFIKKDERRDKMLSLKEF-----FREMIREHIKDQDDDNPRDFIDVYLKEVHKSGEKPSYFHIEQ------------------------------LIQKKCKEEIKDKLQ---GDEKPTQDCISELPYTHATLMEVQRLASVGPMSLPRYTTKDIDVNGYSIPEGTEIYSNFMAFHRDPDFFPEPLEFKPERFLTEDGSRVKKDEHFLPFGLGRRICMGESLARHQLIIFFIMILQNLNISVPIGQEKPDPESCFMGITRIPTPFHVQIR 442          

Query:   34 PSPFLSFPIIGH-AWMIGDDIPRYMD-QCAEKYGPIFRFDMGYLPTVIIGRHEELVEACKMEPMNGRSWGIMPFVRYLFGTDSKGEIYGVAISNGRVWVEQRKFTHTNLNRVGMGKARELEQIVEQEVQVMCERVAKLSE-VGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMQELAECINRHFET-LSPNNLISTLQQYFHRCTKYATDWGIIKGFKDILKLRANVAKEISEFQPDQEGN----FVERFLFE-IESAHPESSFYGEDGRNHLFGQAVDLFVAGTETTSTFLTWTFKFLIMYPEVQEKISIELRHVFGSAKPSLDRRDELPYTNATIQEICRLNPMSVFSIPRLTMSQINLNGIPIPKHTQVMPNLRTINRDPRSFPDPDEFRPERFLDEDGKFVFNERVVLFGRGKRKCVGQVLAMAEIFLFLAHMVHTFKIK 470
            P PF S P++G   ++     P  +D    EK+G I+  D+ +   V++       +    E ++GR  G   + R+  G D  G  YG+  + G +W  QR+F  TNL  +G GK + LE ++  EV  + E + ++ +    V    +  V I NV+W +I     +      +E+ E +    +  +  N  IS    Y            + +  + +L ++  ++K   E + + E N    F++ +L E ++S  P  S      +  L     D F+AG+ETTST L W    + ++ ++Q K   E+    G+  P  +    LP+T ATI E+ R   ++  S+    +  I +    IPK T V+ N    + DP+ FP P EF P RF     K    E+ V +G GKR C+G+ LA  ++F F   +V  + I+
Sbjct:   31 PGPF-SLPLVGSLPFLSSQGSPGILDFALGEKFGSIYTVDVIWSKIVVLNDFGMAKDLFNREDVSGRYQG--QWHRFTKGYD--GIAYGIINNEGPMWQSQRRFALTNLKNLGFGK-KSLESVIYNEVHHLFEVIDEMIDGCSDVLIHDIFHVPIINVLWSIIASHRFEYSQ--AREIVEKLGLDLKKGIHINIFISIFANYV----------PLNESDEAMLYMKRFISKNXDEHKNNLEVNAPKDFIDFYLIEMLKSQDPYFS------KKQLIVMLFDFFLAGSETTSTTLLWIILLMCLHNDIQLKCYQEISQNIGNNFPREEDMKMLPFTLATISEVQRYANIAPASLVHKVLQTIRVGKYLIPKGTSVIANYHKFHMDPKVFPHPHEFNPYRFY----KVPKPEQFVPYGFGKRICMGKSLAKKQLFYFFVMIVQNYIIR 448          

Query:   56 YMDQCAEKYGPIFRFDMGYLPTVIIGRHEELVEACKMEPMNGRSWGIMPFVRYLFGTDSKGEIYGVAI-SNGRVWVEQRKFTHTNLNRVGMGKARELEQIVEQEVQVMCERV---AKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMQELAECINRHFE-------TLSPNNL-ISTLQQYFHRCTKYATDWGIIKGFKDILKLRANVAKEISEFQPDQEGNFVERFLFEIESAHPESSFYGEDGRNHLFGQAVDLFVAGTETTSTFLTWTFKFLIMYPEVQEKISIELRHVF-GSAKPSLDRRDELPYTNATIQEICRLN---PMSVFSIPRLTMSQINLNGIPIPKHTQVMPNLRTINRDPRSFPDPDEFRPERFLDEDGKFVFNERVVLFGRGKRKCVGQVLAMAEIFLFLAHMVHTFK 468
            + D+  + YG  FR   G   T+I+     + E       N  +    PF + L    S G+  G+ + + G  W   R+F+ +    +  G A  L Q  + EV  +   +   AK  +    +      + I N+IW ++ G+  K  DP +Q+  + +    E       T+ P  L I  L++ ++R       + I+        L   V +   +   D++  F++ FL              ED    L     D F+AG ET+S  L     ++++YP +QE  + E+R       +     R  LPYT+A + E+ R     P++ F   R +   I +NG   P +  V  NL  + R    +  PD F P RFL+E G        + FG G+R+C+G+ +     FL +++++H FK
Sbjct:   68 FFDKLHDIYGEDFRLHNGIEDTIILSSLNGIREFS-----NHPNASFRPFNKVLMDIYSDGKDLGMGLGTGGERWKFLRRFSSSAFKSLS-GGASGLNQNFDLEVSEIVAXLRGKAKSPDPIIRNVNIYFDIPILNIIWWLVAGRRYKYGDPAIQKQFDYLKVLLEEPFIAPLTIIPFALYIPPLRKIYNRIRNAMNSFRIL--------LSKIVEERRKDNFTDEKRGFIDLFLKAQLDDKDNPYLSNED----LIMCCQDFFLAGAETSSKTLCTFILYMVLYPNIQENAASEIRDAIQKDTQIKSKDRHLLPYTDAVLMEVRRYATPFPITPF---RCSNKDIRVNGFDXPANVPVQVNLNGVLRSKYCWKAPDIFNPSRFLNEKGAVEIPNAFMPFGFGRRRCIGEDIGNISNFLIVSNLLHNFK 475          

Query:   33 GPSPFLSFPIIGHAWMIGDDIPRYMDQCAEKYGPIFRFDMGYLPTVIIGRHEELVEACKMEPMNGRSWGIMPFVRYLFGTDSKGEIYGVAISNGRVWVEQRKFTHTNLNRV-GMGKARELEQIVEQEVQVMCERVAKLSEVGGV-----DFQKLLPVAINNVIWRMITGKTSKQDDPFMQELAECINRHFETLSPNNLISTLQQYFHR---CTKYATDWGIIKGFKDILKLRANVAKEISEFQPDQEGNFVERFLFEIESAHPESSFYGEDGRNHLFGQAVDLFVAGTETTSTFLTWTFKFLIMYPEVQEKISIELRHVFGSAKPSLDRRD--ELPYTNATIQEICRLNPMSVFSIPRLTMSQINLNGIPIPKHTQVMPNLRTINRDPRSFPDPDEFRPERFLDEDGKFVFNERVVLFGRGKRKCVGQVLAMAEIFLFLAHMVHTFKIKPA 472
            G  P L +  I H + + +   R+  Q   +Y        G LPT +   +  +++   ++  N        F R +     K  +  + +S+G +W   RK    ++  V   GK +E+ + V          +   S  G        FQ L    IN   + + T  + + D   ++     +N  F  ++ N + S L   F+      KY   +G  K   +++K+ AN   E  E    ++ +F+   +   + +H + +    D    +  QA+  F+AG  TTST L      L  +PE+QEK+  E+         S + +D  E  YT+A I+E  R+ P     + R+      + GIPI K T +   +   + +P  FP+P+EF+PERF  E+   +       FG G R C+    AM E  L L  +V  F+I P 
Sbjct:   54 GSPPILWYNYIHHFYFM-EAFKRFKSQTFTRYN-------GSLPT-LTTMNPSIIKQITIKQFNH-------FHRTMHKIKDKNLL--LTLSDGSLWKLLRK----DITPVFTSGKLKEMMEPVSDIANQFVAYIETQSSEGKSIKIQDKFQGLTLDIINACAYGIKTNSSEEPDHELLRHSKMLLNDSF--ITKNVITSVLILLFNSFPGMFKYVDMFG--KANDELIKI-ANSIIETRESHNIEKKDFLNVLVQMRKKSHEDPNTLLNDEI--ITAQAIIFFIAGYSTTSTTLCCLTYMLATHPEIQEKLYKEI--------VSSEDKDFSEHSYTSAVIKETLRMYPPVALHL-RVCAKDTEVEGIPIKKGTIIEMPIYASHYNPEFFPNPNEFKPERFFQENNLEIIPNTYRPFGNGNRSCIAYRFAMMEXQLILEKLVKKFEILPT 466          

Query:   40 FPIIGHAWMIGDDIPRYMDQCAEKYGPIFRFDMGYLPTVII---GRHEELVEACKMEPMNGRSWGIMPFVRYLFGTDSKGEIY----GVAISNGRVWVEQRKFTHTNLNRVGMGKA--RELEQIVEQEVQVMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMQELAECINRHFETLSPNNLIS---TLQQYFHRCTKYATDWGIIKG-FKDILKLRANVAKEISEFQPDQEGNFVERFLFEIESAHPESSFYGEDGRNHLFGQAVDLFVAGTETTSTFLTWTFKFLIMYPEVQEKISIELRHVFGSAKPSLDRRD-----ELPYTNATIQEICRLNPMSVFSIPRLTMSQINLNGIPIPKHTQVMPNLRTINRDPRSFPDPDEFRPERFLDEDGKFVFNERV-----VLFGRGKRKCVGQVLAMAEIFLFLAHMVHTFKIKPA 472
            FP + +   I   IP ++++    YG I++F     P V++     H E+         +   W   P    +    S+ E+Y    G+  S G+ W + R    T L R  + KA  + +  +VE  ++ + E   +  +      + L    + +      TG  +   D  +  L   ++   E+    NL+    +L QY  R   +    G++ G ++ I K   N  +E++    D++   +ER     +++  E+ ++    +N L   A+D+ +AG +T +  +++ F ++    +VQEK+  E+R        SLD  D        Y  AT++E+ RL P +  ++ R+  + I L+   I + + ++     +  DPR   DP EFRPER++     +   ER+     + FG G R CVG+  A  E+ L LA ++  +K++P 
Sbjct:   29 FPFMNYDTEI---IP-FLERSRLVYGDIYKFKAPLGPDVVVLFKPHHAEIAYR------SAGKWPNRPGFHAIQQFRSQKELYSNNSGLLSSQGQDWYDFRSKVQTALLRPRLIKAYHQRVNGVVEDFIKDIFENTLEDGKASADLLEYLYQWGLES------TGVLAF--DRRLGVLNPSLDSSSESQEIINLVQEIFSLSQYLERNMVWKY-IGLLHGKYRQITKC-LNRLEELTIKYVDEKIEMIERKGSCSDTSVIENLYHAGCDKNVLCVLALDMLMAGVDTAANEISFAFHYIAQNQKVQEKLFNEIR--------SLDIDDPNFVENAVYLRATLKEVLRLKPTAYVNV-RMCQNSIELDDYLIQEGSMILFCHIVMCHDPRFVNDPLEFRPERYIKSHPHY---ERLQPFTSLPFGYGPRVCVGKRFANLEMGLLLARIISKYKLEPT 452          

Query:    9 ILALFGVYAVKY--IKKYFWDLRHLKGPS--PFLSF---PIIGHAWM----IGDDIPRYMDQCAEKYGPIFRFDMGYLPTVIIGRHEELVEACKMEPMNGRSWGIMPFVRY--LFGTDSKGEIYGVAISNGRVWVEQRK-----FTHTNLNRVGMGKARELEQIVEQ-----EVQVMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMQELAECINRHFETLS-PNNLISTLQQYFHRCTKYATDWGIIKGFKDILKLRANVAKEISEFQPDQEGNFVERFLFEIESAHPESSFYGEDGRNHLF-GQAVDLFVAGTETTSTFLTWTFKFLIMYPEVQEKISIELRHVFGSAKPSLDRRDELPYTNATIQEICRLNPMSVFSIPRLTMSQINLNGIPIPKHTQVMPNLRTINRDPRSFPDPDEFRPERFLDEDGKFVFNERVVLFGRGKRKCVGQVLAMAEIFLFLAHMVHTFKIKPA 472
            I++L  ++++ Y  + +Y   L +L  P   PFL F   P   H ++      +   R+  Q   +Y        G +PT+             ++P   +   I  F  +   F  + K +   + IS+G +W   RK     FT   L     G    L +I        E Q    +  K+ +     F  L    IN+  + + T  +   D   ++   + +     T + P ++   L   F    KY   +G    +++++K+ AN      E +  ++ +F+   L E+   + E     E   N +   QAV  FVAG  TTS  L      L   PE+Q+++  E   +  S     D   E  YT+A I+E  RL P +     R+      + GI I   T +   +   +  P  FP+P+EF+PERF  E+   +  +    FG G R C+    AM E+ + +  +V  F+I P 
Sbjct:    5 IISLVVIFSLIYFYLNRYHGYLENLPFPQEKPFLCFGSPPFFWHNYVHHFYYTEAFKRFKSQTFTRYT-------GSIPTI-----------STIDPKIIKQVTIKQFNNFHMTFTENVKDKNKSLDISHGPLWKLLRKELTPVFTSGKLK----GMMEPLLEITNDFLFHIESQTTSGKSIKIKQ----KFHGLTLDVINSCAYGIKTNSSQDSDHELLKHAKKLLEDAVVTKNLPTSMFILLLNLFPGMIKYIDIFG--NAYEELIKI-ANSIIANRETENIKKKDFI-NVLVEMRKNNNECP--NELLNNEIITAQAVIFFVAGYVTTSHSLCCLIYVLATNPEIQDQLYQE---ILSSEDQGFD---EHSYTSAVIKEALRLYPPATMHT-RVCTHDTEVEGIFIKNGTIIEMPIYASHYYPEFFPNPEEFKPERFFKENNSEIIPDTFRPFGDGNRICIAYRFAMMELQIVIEKLVKKFEIIPT 454          

Query:   33 GPSPFLSFPIIGHAWMIG-DDIPRYMDQCAEKYGPIFRFDMGYLPTVIIGRHEELVEAC--KMEPMNGRSWGIMPFVRYLFGTDSKGEIYGVAISNGRVWVEQRKFTHTNLNRVGMGKARELEQIVEQEVQVMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMQELAECINRHFETLSPNNLISTLQQYFHRCTKYATDWGIIKG-----FKDILKLRANVAKEISEFQPDQEGNFVERFL--FEIESAHPESSFYGEDGRNHLFGQAVDLFVAGTETTSTFLTWTFKFLIMYPEVQEKISIELRHVFGSAK-PSLDRRDELPYTNATIQEICRLNPMSVFSIPRLTMSQINLNGIPIPKHTQVMPNLRTINRDPRSFPDPDEFRPERFLDEDGKFVFNERVVLFGRGKRKCVGQVLAMAEIFLFLAHMVHTFKIKP 471
            GP+P    PIIG+   I   DI +     ++ YGP++   +G  PTV++  +E + EA     E   GR  G  P    +F   + G   G+A S G VW   R+F+   L  +GMGK R +E  V++E + + E + K +     D   +L  A  NVI  +I        D     L E +N   + LS          +   C  Y        G     FK+   ++  + ++I E +   +      F+  F I     + +   ++   HL     DLF AGTETTST L +    L+ YP V  K+  E+ HV G  + P +  R  +PYT+A I E+ R   +   S+P    S I      IPK T V+ +L ++  D   FP+P++F P  FLDE+GKF  ++  + F  GKR C G+ LA  E+FLFL  ++  F +KP
Sbjct:   32 GPTPL---PIIGNILQIDVKDICQSFTNLSKVYGPVYTLYLGRKPTVVLHGYEAVKEALVDHGEEFAGR--GRFP----VFDKATNG--MGLAFSKGNVWKNTRRFSLMTLRNLGMGK-RSIEDRVQEEARCLVEELRK-TNGSPCDPTFILGCAPCNVICSIIFQDRFDYKDRDFLNLMEKLNEITKILS--------SPWLQICNTYPALLDYCPGSHKQFFKNYASIKNFLLEKIKEHEESLDVTIPRDFIDYFLINGGQEDGNQPLQNRLEHLAITVTDLFSAGTETTSTTLRYAILLLLKYPHVTAKVQEEIEHVIGKHRSPCMQDRSRMPYTDAMIHEVQRFIDLIPNSLPHEVTSDIKFRNYFIPKGTTVITSLSSVLHDSTEFPNPEKFDPGHFLDENGKFKKSDYFIPFSTGKRICAGEGLARMELFLFLTSILQNFNLKP 460          

Query:   50 GDDIPRYMDQCAEKYGPIFRFDMGYLPTVIIGRHEELVEACKMEPMNGRSWGIMPFVRYLFGTDSKGEIYGVAISNGRVWVEQRKFTHTNLNRVGMGKARELEQIVEQEVQVMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMQELAECINRHFET-LSPNNLISTLQQYFHRCTKYATDWGIIKGFKDILK-----LRANVAKEISEFQPDQEGNFVERFLFEIESAHPESSFYGEDGRNHLFGQAVDLFVAGTETTSTFLTWTFKFLIMYPEVQEKISIELRHVFGSAK-PSLDRRDELPYTNATIQEICRLNPMSVFSIPRLTMSQINLNGIPIPKHTQVMPNLRTINRDPRSFPDPDEFRPERFLDEDGKFVFNERVVLFGRGKRKCVGQVLAMAEIFLFLAHMVHTFKIKPAPGQVYTLKSNPGLAFTSYPYLSVVELR 499
            G  +   +      YG IF F +G+   V++     + EA   +         +P    +  T  KG ++      G VW +QRKF+H+ L   G+GK   LE  + +E + + E + K  +     F  ++  A++N+I  +  G+     +   +++   ++R  E  L+   L+  +  +      Y   +G  K  + I K     L+  +         +   +F++ +L  +E     +S  G D  ++LF    DLF+AGT+TT+  L W   ++ ++P +QEKI  E+  V G+ + PSL  + ++PYT ATI E+ RL+ +   SIP +T  +  L G  IPK T ++PNL +++RDP  +  P++F P+RFLD+ G+ +  E  + FG GKR C+G+ LA  E+FL    ++ +F           L    GL    +P+  ++  R
Sbjct:  100 GQGVQLLLADLGRVYGNIFSFLIGHYLVVVLNDFHSVREALVQQAEVFSDRPRVPLTSIM--TKGKGIVFA---HYGPVWRQQRKFSHSTLRHFGLGKL-SLEPKIIEEFRYVKEEMQKHGDAPFNPF-PIVNNAVSNIICSLCFGRRFDYTNSEFKQMLNFMSRALEVCLNTQLLLVNICSWL-----YYLPFGPFKELRQIEKDLTLFLKKIIKDHRESLDVENPQDFIDMYLLHVEEEKKNNSNSGFD-EDYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLHPNIQEKIHEEIARVIGADRAPSLTDKAQMPYTEATIMEVQRLSTVVPLSIPHMTSEKTVLQGFTIPKGTIILPNLWSVHRDPAIWEKPNDFYPDRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFTFVLPKDSKPILTGKYGLTLAPHPFNIIISKR 543          

Query:   33 GPSPFLSFPIIGH-AWMIGDDIPRYMDQCAEKYGPIFRFDMGYLPTVIIGRHEELVEAC--KMEPMNGRSWGIMPFVRYLFGTDSKGEIYGVAISNGRVWVEQRKFTHTNLNRVGMGKARELEQIVEQEVQVMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMQELAECINRHFETLSPNNLISTLQQYFHRCTKY--ATDWGIIKGFKDILKLRAN-VAKEISEFQPDQEGNFVERFLFEI--ESAHPESSFYGEDGRNHLFGQAVDLFVAGTETTSTFLTWTFKFLIMYPEVQEKISIELRHVFGSAK-PSLDRRDELPYTNATIQEICRLNPMSVFSIPRLTMSQINLNGIPIPKHTQVMPNLRTINRDPRSFPDPDEFRPERFLDEDGKFVFNERVVLFGRGKRKCVGQVLAMAEIFLFLAHMVHTFKI 469
            GP P    PI+G+   M    + +   +  EKYG +F   +G   TV++   + + EA     E  +GR  G +  V  +F      + YGV  +NG  W   R+F+   +   GMGK R +E+ +++E Q + E + K   V   D          N+I  ++ GK     DP    L       F  +S  +  S + + FH   KY   T   +    ++I    A  V K      P    +F++ +L  +  E A P S F+      +L   A+ LF AGTETTST L + F  ++ YP + E+I  E+  V G  + PSLD R ++PYT+A I EI R   +    +P +    I   G  IPK T+V P L +   DP  F  PD F P+ FLD +G    NE  + F  GKR C+G+ +A  E+FLF   ++  F +
Sbjct:   33 GPRPL---PILGNFLQMDRKGLLKSFLRLQEKYGDVFTVYLGPRRTVMLCGIDAIREALVDNAEAFSGR--GKIAVVEPVF------QGYGVVFANGERWKTLRRFSLATMRDFGMGK-RSVEERIQEEAQCLVEELRKTEGVLQ-DPTFFFHSMTANIICSIVFGKRFGYKDPEFLRLMNLFYVSFALIS--SFSSQMFELFHSFLKYFPGTHRQVYNNLQEIKAFIARMVEKHRETLDPSAPRDFIDAYLIRMDKEKAEPSSEFH----HRNLIDTALSLFFAGTETTSTTLRYGFLLMLKYPHIAERIYKEIDQVIGPHRLPSLDDRAKMPYTDAVIHEIQRFGDLLPIGVPHMVTKDICFRGYIIPKGTEVFPILHSALNDPHYFEKPDVFNPDHFLDANGALKKNEAFIPFSIGKRICLGEGIARMELFLFFTTILQNFSV 459          

Query:   33 GPSPFLSFPIIGHAW-MIGDDIPRYMDQCAEKYGPIFRFDMGYLPTVIIGRHEELVEAC--KMEPMNGRSWGIMPFVRYLFGTDSKGEIYGVAISNGRVWVEQRKFTHTNLNRVGMGKARELEQIVEQEVQVMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMQELAECINRHFETLSPNNLISTLQQYFHRCTKY--ATDWGIIKGFKDILK-LRANVAKEISEFQPDQEGNFVERFLFEIES--AHPESSFYGEDGRNHLFGQAVDLFVAGTETTSTFLTWTFKFLIMYPEVQEKISIELRHVFGSAKP-SLDRRDELPYTNATIQEICRLNPMSVFSIPRLTMSQINLNGIPIPKHTQVMPNLRTINRDPRSFPDPDEFRPERFLDEDGKFVFNERVVLFGRGKRKCVGQVLAMAEIFLFLAHMVHTFKI-KPAP 473
            GPSP    P++G+   M    + R   +  EKYG +F   +G  P V++   + + EA   + E  +GR  G +  V  +F      + YGV  +NG  W   R+F+   +   GMGK R +E+ +++E + + E + K S+   +D   L     +N+I  ++ GK     DP    L +   + F  +S  +  S + + F    K+   T   I +  ++I   +  +V K  +   P    +F++ +L  +E   + P S F+ ++    L    + LF AGTETTST L + F  ++ YP V E++  E+  V GS +P +LD R ++PYT+A I EI RL  +  F +P          G  IPK+T+V P L +   DPR F  P+ F P  FLD +G    NE  + F  GKR C+G+ +A  E+FLF   ++  F I  P P
Sbjct:   33 GPSPL---PVLGNLLQMDRKGLLRSFLRLREKYGDVFTVYLGSRPVVVLCGTDAIREALVDQAEAFSGR--GKIAVVDPIF------QGYGVIFANGERWRALRRFSLATMRDFGMGK-RSVEERIQEEARCLVEELRK-SKGALLDNTLLFHSITSNIICSIVFGKRFDYKDPVFLRLLDLFFQSFSLIS--SFSSQVFELFPGFLKHFPGTHRQIYRNLQEINTFIGQSVEKHRATLDPSNPRDFIDVYLLRMEKDKSDPSSEFHHQN----LILTVLSLFFAGTETTSTTLRYGFLLMLKYPHVTERVQKEIEQVIGSHRPPALDDRAKMPYTDAVIHEIQRLGDLIPFGVPHTVTKDTQFRGYVIPKNTEVFPVLSSALHDPRYFETPNTFNPGHFLDANGALKRNEGFMPFSLGKRICLGEGIARTELFLFFTTILQNFSIASPVP 464          

Query:    9 ILALFGVYAVKYIKKYFWDLRHLKG---PSPFLSFPIIGHAWMI-GDDIPRYMDQCAEKYGPIFRFDMGYLPTVIIGRHEELVEAC--KMEPMNGRSWGIMPFVRYLFGTDSKGEIYGVAISNGRVWVEQRKFTHTNLNRVGMGKARELEQIVEQEVQVMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMQELAECINRHFETLSPNNLISTLQQYFHRCTKYATDWGIIKGFKDILKLRANVAKEISEFQPDQEGN----FVERFLFEIES-AHPESSFYGEDGRNHLFGQAVDLFVAGTETTSTFLTWTFKFLIMYPEVQEKISIELRHVFGSAK-PSLDRRDELPYTNATIQEICRLNPMSVFSIPRLTMSQINLNGIPIPKHTQVMPNLRTINRDPRSFPDPDEFRPERFLDEDGKFVFNERVVLFGRGKRKCVGQVLAMAEIFLFLAHMVHTFKIKP 471
            +L + G+     +    W   H KG   P P    P++G+   +   DI + +   A++YG IF    G  P V++  +E ++EA   + E  +GR  GI P    +F   +KG   G+  S+G  W E R+F+ T L  +GMGK + +E+ +++E   + + + K +     D   LL     NVI  +I       DD   + L +  + +FE L        +Q Y      +       + FK+I      + +++ E Q   + N    FV+ FL ++E   H + S +  D   +L     D+F AGT+TTS  L +    L+ +PE+  K+  E+ HV G  + P +  R  +PYT+A + EI R   +   S+P      I  NG  IPK T ++P+L ++  D + FP+P++F P  FLDE G F  ++  + F  GKR CVG+ LA  E+FL L  ++  F +KP
Sbjct:    3 LLIILGICLSCVVLLSLWKKTHGKGKLPPGP-TPLPVVGNLLQLETKDINKSLSMLAKEYGSIFTLYFGMKPAVVLYGYEGVIEALIDRGEEFSGR--GIFP----VFDRVTKG--LGIVFSSGEKWKETRRFSLTVLRNLGMGK-KTIEERIQEEALCLIQALRK-TNASPCDPTFLLFCVPCNVICSVIFQNRFDYDDEKFKTLIKYFHENFELLG----TPWIQLYNIFPILHYLPGSHRQLFKNIDGQIKFILEKVQEHQESLDSNNPRDFVDHFLIKMEKEKHKKQSEFTMD---NLITTIWDVFSAGTDTTSNTLKFALLLLLKHPEITAKVQEEIEHVIGRHRSPCMQDRTRMPYTDAVMHEIQRYVDLVPTSLPHAVTQDIEFNGYLIPKGTDIIPSLTSVLYDDKEFPNPEKFDPGHFLDESGNFKKSDYFMPFSAGKRACVGEGLARMELFLLLTTILQHFTLKP 459          

Query:    1 MSSTVGVTILALFGVYAVKYIKKYFWDLRHLKGPSPFLSFPIIGHAWMIGDDIPRYMDQCAEKYGPIFRFDMGYLPTVIIGRHEELVEACKMEPMNGRSWGIMPFVRYLFGTDSKGEIYGVAISNGRVWVEQRKFTHTNLNRVGMGKARELEQIVEQEVQVMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMQELAECINRHFETLSPNNLISTLQQYFHRCTKYATDWGIIKGFKDILKLRANVAKEISEFQPDQEGNFVERFLFEIESAHPESSFYGEDGRNHLFGQAVDLFVAGTETTSTFLTWTFKFLIMYPEVQEKISIELRHVFGSAKPSLDRRDELPYTNATIQEICRLNPMSVFSIPRLTMSQINLNGIPIPKHTQVMPNLRTINRDPRSFPDPDEFRPERFLDEDGKFVFNERVVLFGRGKRKCVGQVLAMAEIFLFLAHMVHTFKIKPAPGQVYTLKSNPGLAFTSYPYLSVVELR 499
            MSSTVGV +L L GVYAVKY KKYFWDLRHL GPSPFLS PI GHAWMIGDDIPRYMDQCAEKYGPIFRFDMGYLPTVIIGR+++ V+A K+EPMNGR+W IMPFVR LFGTDSKGE++GV  SNG VW EQRKF H NLNRVGMGKA+ELE+IVEQEV+VMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFM EL +C+NRHFETLSP+N ISTLQQYFHRCTK ATD GIIKGFKDILKLR  VA++ISE QP+ EGNFVERFLFEIESA+PESSFYG+DGR HLFG AVDLF+AGTETT+TF+TWTFKFLIMYPEVQEKIS EL HVFGSAKPSLDRRDELPYT+ATIQE  RLNP+ VFS+ RLT+S INL G PIPKHTQ++P LRTINRDP+SFPDP+EFRPERFLD+DGKFVF+ERV LFG+GKRKCVG+VLA AEIFLFL HMVH F+IKPAPGQ+YTLKSNPGLAFTS PY +VVE R
Sbjct:    1 MSSTVGVAVLTLIGVYAVKYFKKYFWDLRHLNGPSPFLSLPIFGHAWMIGDDIPRYMDQCAEKYGPIFRFDMGYLPTVIIGRYDDYVDAYKLEPMNGRAWSIMPFVRNLFGTDSKGEVFGVGSSNGPVWAEQRKFMHINLNRVGMGKAKELEEIVEQEVEVMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMVELTDCMNRHFETLSPSNPISTLQQYFHRCTKVATDLGIIKGFKDILKLRDTVAEQISELQPESEGNFVERFLFEIESANPESSFYGKDGRRHLFGNAVDLFIAGTETTATFMTWTFKFLIMYPEVQEKISNELCHVFGSAKPSLDRRDELPYTHATIQETIRLNPLGVFSVARLTLSPINLKGTPIPKHTQILPYLRTINRDPKSFPDPNEFRPERFLDQDGKFVFDERVTLFGKGKRKCVGEVLAKAEIFLFLTHMVHNFRIKPAPGQIYTLKSNPGLAFTSDPYQAVVESR 499          

Query:  103 MPFVRYLFGTDSKGEIYGVAISNGRVWVEQRKFTHTNLNRVGMGKARELEQIVEQEVQVMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMQELAECINRHFETLSPNNLISTLQQYFHRCTKYATDWGIIKGFKDILKLRANVAKEISEFQPDQEGNFVERFLFEIESAHPESSFYGEDGRNHLFGQAVDLFVAGTETTSTFLTWTFKFLIMYPEVQEKISIELRHVFGSAKPSLDRRDELPYTNATIQEICRLNPMSVFSIPRLTMSQINLNGIPIPKHTQVMPNLRTINRDPRSFPDPDEFRPERFLDEDGKFVFNERVVLFGRGKRKCVGQVLAMAEIFLFLAHMVHTFKIKPAPGQVYTLKSNPGLAFTSYPY 492
            MPF++ L GTDSK +++GV  S G VWVEQRK  H  LN+VGMGK   +E+++ +E Q +C+R A+ ++ G V  +  LPVAINNVIWRMITG+T+KQDDPFM E+ E ++ HF+ +SP++++STL QYFHR TK A  +G ++G++D + L  NV  E+ +F+  Q+GNFVER+  EI  A PESSFYG+DG NHL GQA+D F+AGTETT+TFL WT K+LI YPE+QEK++ E+  VFGS   ++ ++D+L YT A I E  R NPM + SIPR+TM+ + LNG  IPKHTQ+ P  +++NRDP++F DPD+FRPERFLD++G FV N+RV+LFG+G+RKCVG+VLA AEIFLFL + +H+FKI P  G+ Y+  SNPGL FTS P+
Sbjct:    1 MPFIQGLSGTDSKSQVHGVGSSKGSVWVEQRKLAHIGLNKVGMGKTDAMEEMIGEEAQTLCDRFAEKAKFGPVQIKGKLPVAINNVIWRMITGRTTKQDDPFMNEMTERMDSHFKFMSPSSIVSTLMQYFHRITKVAVKFGFVRGYQDFIVLLNNVRNEVKDFRAVQDGNFVERYRDEIAKASPESSFYGKDGENHLVGQAMDFFIAGTETTTTFLEWTLKYLINYPEIQEKLAKEIETVFGSRPSNIGQKDQLHYTQAFILESYRHNPMGILSIPRMTMNDVTLNGTFIPKHTQIFPYFKSMNRDPKAFEDPDQFRPERFLDKNGNFVTNDRVILFGKGRRKCVGEVLAKAEIFLFLTYFIHSFKIAPVAGEDYSDASNPGLVFTSSPF 390          

Query:    3 STVGVTILALFGVYAVKYIKKYFWDLRHLKGPSPFLSFPIIGHAWMIGDDIPRYMDQCAEKYGPIFRFDMGYLPTVIIGRHEELVEACKMEPMNGRSWGIMPFVRYLFGTDSKGEIYGVAISNGRVWVEQRKFTHTNLNRVGMGKARELEQIVEQEVQVMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMQELAECINRHFETLSPNNLISTLQQYFHRCTKYATDWGIIKGFKDILKLRANVAKEISEFQPDQEGNFVERFLFEIESA--HPESSFYGEDGRNHLFGQAVDLFVAGTETT 314
            + +G+   A   +Y V Y+K+YFWD R +KGPS FLS PIIGHAW +  +  + ++     YG +FRFD+G  P++++   EE  E C+M+  NGR +GI+P V+ +FGTDS+GE++GV+ SNG+ W EQRKF H NLN  GMGK   LE I+ QE ++  ER+A  ++ G V  +K  PVAINN++WRMITG TS QDDP M  L + +NRHFE+LSP+N+ + LQQYFHR T       +   FKD+  +R  +  E  +  PD  G +V +F  EI++A  +P+SSF+  DG  HL G AVDLFVA    T
Sbjct:    2 ALIGIIFGAFLCLYLVHYVKRYFWDYRDMKGPSVFLSVPIIGHAWALSPNPHKTLEDLKTTYGNLFRFDIGPYPSLVVAGLEEFQEMCRMDVFNGRFFGILPAVQTVFGTDSRGEVFGVSASNGQTWAEQRKFMHQNLNVAGMGKKSTLENIINQEAEIAAERMASGAKNGPVCIKKFFPVAINNIVWRMITGNTSSQDDPLMLYLTDRMNRHFESLSPSNITAILQQYFHRFTNILDKLNMPTCFKDLYIIREFLDNEFKKIDPDPNGLYVAKFKAEIQAAASNPQSSFHETDGEFHLSGHAVDLFVAAPPQT 315          

Query:   10 LALFGVYAVKYIKKYFWDLRHLKGPSPFLSFPIIGHAWMIGD-DIPRYMDQCAEKYGPIFRFDMGYLP-TVIIGRHEELVEACKMEPMNGR----SWGIMPFVRYLFGTDSKGEIYGVAISNGRVWVEQRKFTHTNLNRVGMGKARELEQIVEQEVQVMCERVAK-LSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMQELAECINRHFETLSPNNLISTLQQYFHRCTKYATDWGIIKGFKDILKLRANVAKEISEFQPDQEGN----------FVERFLFEIESAHPESSFYGEDGRNHLFGQAVDLFVAGTETTSTFLTWTFKFLIMYPEVQEKISIELRHVFGSAKP-SLDRRDELPYTNATIQEICRLNPMSVFSIPRLTMSQINLNGIPIPKHTQVMPNLRTINRDPRSFPDPDEFRPERFLDEDGKFVFNERVVLFGRGKRKCVGQVLAMAEIFLFLAHMVHTFKIKPAPGQVYTLKSNPGLAFTSYP 491
            + +F    + Y  K F  +     P+  L  P+IG+  +  + +I   +D+  ++YG +   ++G  P  VIIG ++ L E  K E    R    +WG   + R   G DS+G ++    S G+ W EQR+F    L   GMGK+  +E+++++E++ +C+++ K L++   VD    L V   N +W +ITG     DDP + EL   I+   E     NL+       H   + +   G  K  + +  L   VAK+I E Q + E N          F++ FL +I+ +   SSF+G+ G N+L    +DL  AG ETTST L W+  ++I YP++Q K+  E+    G ++P +LD +  LP+T A IQE+ R+  +    IP    + I +  + IP+ T +MPNL  I R+P +FP+P+ F+PERFLD  GK+   E  + F  GKR C+G+ LA+AE+FLF A ++  +  K     +  +   P + FT  P
Sbjct:    5 VVVFCALVLIYWWKNFARIPGPNFPNGPLGLPLIGYVPVFTEKNILVGLDKAHDQYGEVMSVNLGPSPRMVIIGDYQVLKEVFKEESSTFRPVEMNWG-NAYFRSGNGYDSRGLLF----SQGQEWTEQRRFALRRLRDFGMGKS-SMEELIQEEIRQLCQKLDKQLNQPLKVDLTYNLSVV--NALWTVITGSRLSLDDPKLIELVVKIDELMEMSGNVNLVQMFPWTRHIIPELS---GWNKSKEIMYGLINFVAKDIKEHQDNFEANKEMLQENPNDFIDAFLAKIQESPESSSFHGQLGINNLKAGLLDLLFAGIETTSTALCWSTLYMIKYPDIQRKVQNEIFKYVGKSRPVNLDDKPNLPFTEAVIQEVLRITCIGPLGIPHCAQTDIKVGNLWIPQGTSIMPNLHRITRNPAAFPEPNNFKPERFLDSQGKYCKIESNIPFSIGKRDCLGKSLALAELFLFFASLMQRYSFKSVHDDLSRVDLEPKVNFTQAP 493          

Query:   12 LFGVYAVKYIKKYFWDLRHLKG-------PSPFLSFPIIGHAWMIGD-DIPRYMDQCAEKYGPIFRFDMGYLPT---VIIGRHEELVEACKMEPMNGRSWGIMPFVRYLFGTDSKGEIYGVAISNGRVWVEQRKFTHTNLNRVGMGKARELEQIVEQEVQVMCERVAKLSEVG-GVDFQKLLPVAINNVIWRMITGKTSKQDDPFMQELAECINRHFETLSPNNLISTLQQYFHRCTKYATDWGIIKGFKDILKLRANVAKEISEFQPDQEGN-----FVERFLFEIESAH--PESSFYGEDGRNHLFGQAVDLFVAGTETTSTFLTWTFKFLIMYPEVQEKISIELRHVFGSAK-PSLDRRDELPYTNATIQEICRLNPMSVFSIPRLTMSQINLNGIPIPKHTQVMPNLRTINRDPRSFPDPDEFRPERFLDEDGKFVFNERVVLFGRGKRKCVGQVLAMAEIFLFLAHMVHTFK-IKPAPGQVYTLKSNPGLAFTSYP 491
            +FG+  V  +  + +   +LK        P P+  +P++G+  +I D ++   + +  + YGP+F  ++G  P+   VIIG ++ L EA K   +  R   I  +  Y+   D      G+  S G  W EQR+FT  NL   G GK+  +E +++ EV+ + E +   +EVG  V F+     ++ N +W ++ G+    +DP ++E+   +N    +   NNLI+      H   +++   G  K  K   K+   +   ISE Q   + N     F++  L +I  +   P SSF+G+ G  +L    +DLF+AG ETTST L W+   L+ +PE+QEK+  E++   GS + PS+D + ++PYT A +QEI R + ++   I R     + +    +PK T V  +L  I  DP+ FP+P+ F P RFLDE+G+F  N++ V+F  GKR C+G+ LA+AE+FLFL  +V  F+ + P  G + +L+   G  FT +P
Sbjct:    1 MFGLLFVFCVVLFLYKFWYLKTKIPPNFPPGPY-GWPLVGYYPLIKDSNLSNGLAKLQDIYGPVFSINLG--PSERYVIIGDYDILEEAFKDYTLTPRPSLIQWYNEYIRHGDGYEYSRGLIFSKGEEWKEQRRFTLRNLRDFGFGKSG-MESLIKMEVEELLEIME--TEVGTDVPFKNKFYASVINALWTILNGERVGLNDPTLKEVIHYVN-EIVSQDMNNLINVFPAIRHVSKEWS---GFNKAMKPAFKILEYIKNTISEHQKTHDPNSQARDFIDVVLNKIHESQDDPNSSFHGQLGLQNLEAGVLDLFIAGIETTSTALVWSCLILVTFPEIQEKVYQEIQKNVGSNRLPSMDDKAKMPYTEAVMQEILRFSCIAPLGIFREADRDVKVGDYFLPKGTVVFSHLYAIVNDPKVFPNPERFDPTRFLDENGQFKRNDKNVVFSTGKRDCLGKTLAIAELFLFLTGLVQKFQFLPPTNGTLPSLECVFG--FTRHP 489          

Query:   24 YFWDLRHLK------GPSPFLSFPIIGHAWMIGDDIPRY------MDQCAEKYGPIFRFDMGYLPTVIIGRHEEL------VEACKMEPMNGRSWGIMPFVRYLFGTD-SKGEIYGVAISNGRVWVEQRKFTHTNLNRVGMGKARELEQIVEQEVQVMCE----RVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMQELAECINRHFETLSPNNLISTLQQYFHRCTKYATDWGIIKGFKDI----LKLRANVAKEISEFQPDQEGNFVERFLFEI-ESAHPESSFYGEDGRNHLFGQAVDLFVAGTETTSTFLTWTFKFLIMYPEVQEKISIELRHVFGSAK-PSLDRRDELPYTNATIQEICRLN---PMSVFSIPRLTMSQINLNGIPIPKHTQVMPNLRTINRDPRSFPDPDEFRPERFLDEDGKFVFNERVVLFGRGKRKCVGQVLAMAEIFLFLAHMVHTFKIKPAPG 474
            YFW  +  K      GP+    +PI+G A  + +   +       + +  ++YG IF F +G    V I + E++       E     P+ G +     F       + +K    G+ +SNGR W EQR+F    L   G GK+  +E  ++++V+++ +    R  K +E+G     + L +AI N +W ++ G+  K +DP ++ + +  N    +  P  LI+ L    H+   Y   +  + G+  I     KL A +   I   Q     ++++  L EI ++    SSFYGE G+  L    +DLF+AG ETTS+ L W+F +L+ YPE Q KI  EL  V GS + P+LD +  L YTNA +QE  RL    P+SVF     T   + ++G  IP+ T V+P+L  +  DP  FP+P  F+P+RFLDE+G F+ NERV+ FG G+R C+G+ LA  E+FLF   ++  F +   PG
Sbjct:   15 YFWKCKTSKPKSFPPGPA---RYPILGSAMSLQNPKTKKPELFYGIRKLQQEYGSIFGFYLGNQSAVAITKFEDIKEILSKSETAHRPPVIGLAAKPGKFTAQEVDPELNKDNPPGIILSNGRYWSEQRRFMLKTLREFGFGKS-SMEAGIQEDVKMLIDHLALRAGKPTEIG-----ESLNIAIINSLWSILVGEKLKLNDPKLEMVVKATNDLITSEGPTGLIANLLP--HKSMIYWPFFKQVSGYSLIESIMKKLEAFMLPYIENHQ--NSDSYIDEMLREIAKTTDKTSSFYGERGQFALINNVIDLFMAGVETTSSSLLWSFLYLLHYPECQAKIQEELDRVCGSNRLPNLDDKPSLHYTNAFLQESLRLTCFVPLSVF---HFTSEDVTVHGYVIPEKTMVIPSLYHVMHDPDHFPEPGLFKPDRFLDENGHFMANERVIPFGVGRRICLGKSLAEKELFLFFTGILQRFSVLNVPG 481          

Query:   16 YAVKYIKKYFWDLRHLKGP-----SPFLSFPIIGHAWMIGDDIPRYMDQCAEKYGPIFRFDMGYLPTVIIGRHEELVEACKMEPMNGRSWGIMPFVRYLFGTDSKGEIYGVAISNGRVWVEQRKFTHTNLNRVGMGKARELEQIVEQEVQVMCERVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMQELAECINRHFETLSPNNLISTLQQYFHRCTKYATDWGIIK-GFKDILKLRANVAKE-ISE----FQPDQEGNFVERFLFEIESAHPESSFYGEDGRNHLFGQAVDLFVAGTETTSTFLTWTFKFLIMYPEVQEKISIELRHVFGSAK-PSLDRRDELPYTNATIQEICRLNPMSVFSIPRLTMSQINLNGIPIPKHTQVMPNLRTINRDPRSFPDPDEFRPERFLDEDGKFVFNERVVLFGRGKRKCVGQVLAMAEIFLFLAHMVHTFKIK 470
            +AV  +    W  ++   P      P  + P IGH + +G+ I +   +   +YG IF   +G   T+I+   + + E+   E    R      F+  L GT S G   GV  SNG+ W EQR+F    L   G GK +++E+I++ +V  +C  + +  +   +    +  V++ N +W + TG++  QDDP +Q + +  N   E  S  +L+      F    K  +  G+    FK  ++    V K+ I E    F P+   +F++  + E ++     SF+G+DG+ +L     DLF AG+ T S  LTW   FL  YP++Q KI  E++ V G  + P+   R  +P+T ATI EI RL  +   S+PR         G  IPK TQ+ PNL  +  DP+ F +P +F P R+++E GKFV +  V+ FG GKR+C+G+ LA  E+F F   +V  FK+K
Sbjct:    6 FAVTCVLALIWWYKNYTQPKGFPNGPSFALPFIGHGYRLGNSIIKSYHRFRGEYGDIFGLFLGSSRTIILNDFDSIQESGFHEDFMDRP----KFLAGLKGTLSDGGEPGVIFSNGKQWSEQRRFALRTLRDFGFGK-QKMEEIIDDQVSQLCS-ILESKQGQPMSVFGVFNVSVLNGLWSITTGQSLSQDDPKIQRINQLFNESDE--SSASLMFLFAILFPNLEKLLSKTGLWSMKFKTAMEEIGKVCKQPIREHEETFDPNNLRDFIDTHIQEQQNPESGISFHGQDGKLNLQVVTEDLFAAGSSTVSMTLTWAVLFLANYPDIQTKIQNEIKAVTGGNRVPTNSERQNMPFTEATIHEIQRLANIVPNSVPREATKDTYFRGYFIPKGTQIFPNLGEVLMDPKHFSNPSKFDPSRYINESGKFVPSPYVIPFGLGKRRCLGETLARVELFKFFTGLVDHFKMK 464          

Query:   15 VYAVKYIKKYFWDLRHLKGPSPF----LSFPIIG-HAWMIGDDIPRYMDQCAEKYGPIFRFDMGYLPT---VIIGRHEELVEACKMEPMNGRSWGIMPF---VRYLFGTDSKGEIYGVAISNGRVWVEQRKFTHTNLNRVGMGKARELEQIVEQEVQVMCERVAKLSEVG-GVDFQKLLPVAINNVIWRMITGKTSKQDDPFMQELAECINRHFETLSPNNLISTLQQYFHRCTKYATDWGIIKGFKDILKLRANVAKEISEFQPDQEGN-----FVERFLFEI--ESAHPESSFYGEDGRNHLFGQAVDLFVAGTETTSTFLTWTFKFLIMYPEVQEKISIELRHVFGSAK-PSLDRRDELPYTNATIQEICRLNPMSVFSIPRLTMSQINLNGIPIPKHTQVMPNLRTINRDPRSFPDPDEFRPERFLDEDGKFVFNERVVLFGRGKRKCVGQVLAMAEIFLFLAHMVHTFK-IKPAPGQVYTLKSN 482
            V  V ++ KY W L+  + PS F    +  P++G +  + G ++     +  +KYG +F  ++G  P+   VIIG H+ LVE+ K   +  R   I  F    RY  G  ++G ++    S G  W+EQR+ T  +L   G GK   +E ++  E+Q + E +   +E+G  V F+     +I NV+W ++TG+    +DP MQE+   ++      +P  L++      H     +   G       I ++ A +   +++ Q   + N     F++  L +I    ++P SSF+G+ G  +L    +DLF AG ETTS  L+++  +++ +P++QEK+  E++   G  + PS++ R + PYT A IQEI R + ++   I R++   + L    IPK T V  NL  + RDP+ FPDP++F P RFLD+DG F  NE+ + FG GKR C+G+ LA+AE ++F A ++  F+ + P+ G++  L+ +
Sbjct:    8 VLCVLFLYKY-WYLK-TRIPSKFPPGPIGLPVVGCYDILSGPNLNASFARLHQKYGSVFSVNLG--PSDRFVIIGDHDILVESFKDMSLTTRPEIIQWFNVYSRYGDGHTARGLMF----SEGDEWLEQRRVTLRHLRDFGFGKT-GMEALILNEIQELLEVME--TEIGTDVRFKGKFNSSIINVLWTIMTGRRCSLNDPKMQEVIHAVDEVVSQSNPTALVNIFPPSRHVIPGLS---GFTAIMIPIRRMIAFIQDTLNDHQASHDPNAEPRDFIDAHLNKIHESESNPSSSFHGQIGLQNLEVSMLDLFFAGVETTSNVLSFSVLYMVNFPDIQEKMFQEIKAKIGLYRLPSMNDRPDTPYTEAVIQEILRYSAIAALGIFRVSSRDVQLGPYQIPKGTTVFSNLLAVLRDPKIFPDPEKFDPTRFLDKDGNFQKNEKNIAFGTGKRDCLGKSLALAEFYIFFAALIQKFEFLPPSSGEIPDLEPD 482          

Query:   30 HLKG--PSPFLSFPIIGHAWMIGDDIPRYMDQCAEKYGPIFRFDMGYLPTVIIGRHEELVEACKMEPMNGRSWGIMPFVRYLFGTDSKGEIYGVAISNGRVWVEQRKFTHTNLNRVGMGKARELEQIVEQEVQVMCE----RVAKLSEVGGVDFQKLLPVAINNVIWRMITGKTSKQDDPFMQELAECINRHFET-LSPNNLISTLQQYFHRCTKYATDWGIIKGFKDILKLRANVAK----EISE-FQPDQEGNFVERFLFEIESAHPESSFYGEDGRNHLFGQAVDLFVAGTETTSTFLTWTFKFLIMYPEVQEKISIELRHVFGSAK-PSLDRRDELPYTNATIQEICRLNPMSVFSIPRLTMSQINLNGIPIPKHTQVMPNLRTINRDPRSFPDPDEFRPERFLDEDGKFVFNERVVLFGRGKRKCVGQVLAMAEIFLFLAHMVHTF 467
            H KG    P  + P IGH + +G+ I +   +   +YG IF   +G   T+I+   + + E+   E    R      F+  L GT S G   GV  SNG+ W EQR+F    L   G GK +++E+I++ +V  +C     +  +   V GV       +++ N +W + TG++  Q DP +Q + + +N   E+  SP   ++ +     +       W  ++ FK  L+    V K    E  E F P+   +F++  + E ++     SF+G+DG+ +L     DLF AG+ T S  LTW   FL  +P++Q KI  E++ V G  + P+   R  +P+T ATI E+ RL  +   S+PR      +  G  IPK TQ++PN+  +  DP+ FP+PD+F P RF++E GKFV +  V+ FG GKR+C+G+ LA  E+F F   +V  F
Sbjct:    1 HPKGFPNGPSFALPFIGHGYRLGNSIIKSYHRFRGEYGDIFGLFLGSSRTIILNDFDSIQESGFHEDFMDRP----KFLAGLKGTLSDGGEPGVIFSNGKQWSEQRRFALRTLRDFGFGK-QKMEEIIDDQVNQLCSILESKHGQPMSVFGV-----FNISVLNALWTITTGQSLSQKDPQIQRINQLLNEFDESSASPWIFVALMLPALEKLLTATGLWKNLE-FKTALEEIGKVCKRPILEHEETFDPNNLRDFIDAHIQEQQNPESGISFHGKDGKLNLQVVTEDLFAAGSSTVSMTLTWAVLFLANHPDIQAKIQNEIKAVTGGNRVPTNSERQNMPFTEATIHEVQRLGNIVPNSVPREASKDTHFRGYFIPKGTQIVPNIGEVLMDPKHFPNPDKFDPNRFINESGKFVASPFVIPFGLGKRRCLGETLARVELFKFFTGIVDHF 440          

Query:   29 RHLKGPSPFLSFPIIGHAWMIGDDIPRYM-DQCAEKYGPIFRFDMGYLPTVIIGRHEELVEACKMEPMNGRSWGIMPFVRYLFGTDSKGEIYGVAISNGRVWVEQRKFTHTNLNRVGMGKARELEQIVEQEVQVMCERVAKLSEVGGVDFQKLLPV--AINNVIWRMITGKTSKQDDPFMQELAECINRHFETLSPNNLISTLQQYFHRCTKYA--------TDWGIIKGFKDILKLRANVAKEISEFQPDQEGNFVERFLFEIESAHPESSFYGEDGRNHLFGQAVDLFVAGTETTSTFLTWTFKFLIMYPEVQEKISIELRHVFGSAK-PSLDRRDELPYTNATIQEICRLNPMSVFSIPRLTMSQINLNGIPIPKHTQVMPNLRTINRDPRSFPDPDEFRPERFLDEDGKFVFNERVVLFGRGKRKCVGQVLAMAEIFLFLAHMVHTFKIKPAPGQVYTLKSNPGLAFTSYPY 492
            RH   PSPF S P +GH  +I  + P+ M D+  EKYG IF   MG +  V +   + + E    +  N      +P  + +F +       G+  SNG +W +QR+FT T L   G GK R LE+ +++E Q + E      +  G  F     V  A++NVI  +I G   +  D   Q+L + +N  F  +   +++S L   F    KY          +W  +K F     ++  + K   ++ P +  +F++ +L E+     ++S  G     +L    +DL +AGTETTST + W   F+  YPE+Q ++  E+  V G A+ P+L  RD +PYTNA I E+ R + +  F++PRLT+    ++G  IPK T +M +L ++  D   +  P+ F P  FL +DG+F  NE  + F  GKR C+G+VLA +E+FLF   ++  F  +  P    +L    G+A    PY
Sbjct:   34 RHFP-PSPF-SLPFLGHFHLINPNNPQAMVDKLREKYGDIFSLQMGQVTFVCVNGLQMIKEVLINQAENFMDRPEIPIDKEIFSS------LGLISSNGHLWKQQRRFTLTTLRNFGFGK-RGLEERIQEECQYLVE---AFGQEQGNPFNPHYKVTNAVSNVICSVIFGNRFEYHDEKFQKLLKLLNETF--VLHGSVMSQLYNAFPSIVKYLPGSHQTIFKNWKCMKSF-----VQEKIDKHKEDWNPSESRDFIDSYLTEMT----KNSVRGSLQEENLVACTLDLLLAGTETTSTTIRWALLFMAKYPEIQARVQAEIDAVIGQARQPALQDRDNMPYTNAVIHEVQRKSNIIPFNVPRLTIKDTFVDGFFIPKDTIMMTSLTSVMFDKNVWETPEAFNPGHFL-KDGQFYKNEYFMPFSIGKRSCLGEVLARSELFLFFTSLLQKFTFQAPPDTTLSLNIQMGIAIAPQPY 485