multidrug resistance-associated protein 1 isoform x3, snap_masked-scaffold1304_size49437-processed-gene-0.4 (gene) Tigriopus kingsejongensis
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Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000002221 (supercontig:LSalAtl2s:LSalAtl2s1420:21426:31801:1 gene:EMLSAG00000002221 transcript:EMLSAT00000002221 description:"maker-LSalAtl2s1420-augustus-gene-0.12") HSP 1 Score: 1122.46 bits (2902), Expect = 0.000e+0 Identity = 645/1556 (41.45%), Postives = 926/1556 (59.51%), Query Frame = 0
Query: 8 FC--RDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTW-TRGRASTVSSKYGPLFLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFVGLAL-LQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVEEWVLLITYVPIILGLFIAHCWVDIDPRAAEDLSLED----------KASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQ----------------WRKQAEDKLVDFTSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHMDSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNV-IHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTS------------NPVTSEVETDELKVLATTTKEPPK-REVRVPS-----------------------EEVESPEETDNLIEET-----ADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWAD------------HNEAHPETGSD---RTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLI---YFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
FC RDPF+D D WNT DPN T C R T+LV +PC LF A L + IY+ + ++ R + + L+ F L+ V+L G+ GS + P +L + P + LA+ + V++ G ISP L F+L L I+ M++ T + + I+ F+ H +V+ P ED ++ D +S S + FSWLD LLW G K L + +L S++ V F ++ + K ++ V +P +S+ P L + G L A ++ + L FV P I+K +IK + E +W+G Y ++L SS + ++ + +++ ++++ SL+ +Y+K+LR+ ++ S GE+ N MSVDAQ+IV+ PY+ + +P I IA+Y L+ L + LAG++V + IP N F + K LQ Q++ KD R+KL+NE++ GIK++KLYAWE F+ I +R E+KI+ G L A +F + +P LV++ F ++ P +VL ++K FV + LFN++R PL P + V VS+KRIN+F+N+ EID V TA AI + +A L W+SD+ + ILS ++L I GSL A+VGTVG+GKSSLLS+ LGEM+K+SG + VRGSIAY QQAW+ N +L++NILF++ + YT+++ C L+ DL +L D TEIGE GINLSGGQKQRVSLARAVYS +DIYLLDDPLSAVD+HVGK I+ V+ S+ G LKDKTRV+VTH V +L D IIV+K+G+V+E G+Y++LL AF+EF++Q+ S + + +EL T K+ + R V + S +E E TDN ++T ++EK G V +Y YV+++ + + ++ L+N L+ W+D N E D +YL +YGG + Q I+ + ++C +A++ +H+++L+ +++SPM+FFDT P GRI+NR D+D +D V+P L I C LS ++VV +TP+F IIP LI YFF+QR +V S+Q+KR ES ++S I + FSET++G A+IRAY Q F+ ES+++V F +NRWL +R+EV+GNL+VF AA+ AVL R++LSPG+ GLS++YAL + +LNW++RM E+ETN VA+ERI EYT E EA W + D K WP +G +SFK+Y+TRYR GLD VLK + +++ EKIGI GRTGAGKSS TLS+FRIIE V G I+IDG DI +LGLH LRSRITIIPQDPVLF+G+LR NLDP + +++ I A+ H+HLK I LK GL + +SEGGEN S+GQRQLICLARALLR+T++L+LDEATAAVDL TD+LIQ TIR EF+ TVITIAHRLNTI+D +I V +G+ E+G+ AELLA+ S +M +DAGL
Sbjct: 20 FCSDRDPFWDPDYAWNTNDPNFTSCFRKTILVWIPC-LFFWAFLPFHIYKLYHSKARKVPLKTLGRVKALSCFILILIAFVDL--------GY-WGSKEFYPKDLIN-PIIRAITFLAVFILLFVERARGYRISPLLTSFFLIYFATNTIDLYGHIRWVMMSGTTXLADITFFLHFFCIIVSFLCHFFVEPRP-LYEDTAVNDIKSNNPCPLITSSFPSQISFSWLDSLLWTGFKRNLSFDDLWDLVPSLSSRTVVPIFLQRLDSALRRVKTNENGITYAKGDDNVEVKTKHEKKPQLSILPALARTFGPSILSAAVIKIVSDSLNFVPPLILKRIIKFSTNQEELWKGILYAVILFASSTVGSLVLSKFFYKMYVVGMKIKTSLISTIYRKALRVPTSTKKNISTGEIVNLMSVDAQKIVDLMPYINTVWSAPFQITIAIYLLWQTLGPSVLAGVLVMILLIPFNGFIASRTKTLQTNQMKEKDERIKLLNEVVQGIKIVKLYAWEQSFLDIISNVRSKEVKILTHIGYLQAGNSFIWTCAPFLVSLVTFATFILSSPENVLDSEKAFVCLTLFNILRFPLSMLPMIIGSMVLAGVSIKRINKFMNSEEIDEEAVEKKTAYPDDKFAINLEKACLKWESDEDKN-ILSDVSLDIEVGSLVAVVGTVGSGKSSLLSAILGEMDKVSGLITVRGSIAYGAQQAWVLNTSLKNNILFNKSYDGDKYTRIVEACALKSDLDMLPGGDETEIGEKGINLSGGQKQRVSLARAVYSGSDIYLLDDPLSAVDSHVGKHIYDNVISSSSGILKDKTRVMVTHGVTYLPFTDKIIVMKDGRVSEIGTYKELLRQKGAFAEFIVQFLSEANENEVNENIKHDIEESFGKNELLEQITKAKQIVRERSVSLNSGDLVTSLVKNNPTNSASGSTTSLKENSGDESTDNDTKQTRPTTSQTQQYQDEKVETGSVKWNIYMHYVKNMSIILVVACSSCFVIYQALNTLSNVLLAWWSDAVMKIEVRTGLNDNRTLDEINQDIMDXQVYYLSIYGGYCLGQGIVVVMGFVFMYLACMEAAQRLHNQMLESILKSPMSFFDTTPQGRILNRLGKDLDVLDSVMPMVLRGWISCFLGVLSSLIVVMVTTPVF---IIPASLIIICYFFIQRIYVATSRQLKRLESSSRSPIXSFFSETVSGAATIRAYGQSSTFISESESKVDDNQKANFPATVSNRWLAVRLEVVGNLIVFTAALLAVLGRDSLSPGLVGLSVSYALAVTASLNWLVRMASEVETNIVAVERIQEYTKAEKEAPWIIE-DTKPDEDWPRKGEISFKNYSTRYREGLDYVLKNVSLDIEGGEKIGIVGRTGAGKSSFTLSMFRIIEPVTGNIIIDGVDITKLGLHQLRSRITIIPQDPVLFSGSLRRNLDPLDEYNETNIMEAISHSHLKPFIDSLKDGLEYHVSEGGENLSLGQRQLICLARALLRRTRVLILDEATAAVDLETDNLIQKTIRSEFKDSTVITIAHRLNTIMDYSKILVLKNGERVEYGTVAELLADKKSQFYSMCSDAGL 1558
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000008248 (supercontig:LSalAtl2s:LSalAtl2s498:229862:245360:1 gene:EMLSAG00000008248 transcript:EMLSAT00000008248 description:"maker-LSalAtl2s498-snap-gene-2.25") HSP 1 Score: 1039.25 bits (2686), Expect = 0.000e+0 Identity = 611/1529 (39.96%), Postives = 890/1529 (58.21%), Query Frame = 0
Query: 3 VGQRPFCRDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPC-ILFLIASLIWSIYQTWTRGRASTVSSKYGPLFLAKFTFTLVILVNLL-----GQFCYTSGHVGGSDKLVPSELFHYPCLLVFVGLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQS-----RMVASGTVEEWVLLITYVPIILGLFIAHCWVD----IDPRAAEDLSLED--KASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKA--FTKQWRKQAEDKLVDFTSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHM-DSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLL-ADGKAFSEFLIQYTSNPVTSEVETDE-----LKVLATTTKEPPKREVRVPSEE---------------------------VESPEETDNLIEETADDL----IEEEKTVAGRVGAKVYWTYVQSIGT-SQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLP-LDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAG 1472
+G FC DP ++ +L W T DP T C T+LV VP ILFL+ Y+ WT SS+ +L F+ ILV L +F + + D ++ + + L F+ + +LQ + + G S PLF+FWL E+ ++ R+ + V ++I Y P+++ L W D + DL+ AS S L FSW D +++ WK + D K+ W ++ E ++ +P LWP L ++ L + + F + F +PQ++ L+I + D EP+W+G+ Y + + ++T+ + + +I+ +++R SL +++ K++ L + +++ SVGE TN M++D+QR+++ Y+ + SPL I+IAMY L+ L ASLAGL V + IPIN+ K VKK Q+Q KD R+KLM+++L GIKVLKLYAWE F+ + R+ EI +K + A +F + S+P LV + F YV +D ++LT FV++ LFNL+R PL P ++++++ VSL RIN FLN ++D + H + HA++M +L+W++D+G++ L ++L I GSL AIVG VG+GKSSLLS LGEME + G + V G Y PQQ W+QN TLR+NILF + F+ Y +VI C L PDL +L D TEIGE GINLSGGQK RVSLAR ++ DIY+LDDPLSAVD HVG+ +F V+ S G LK+KTR+ VTH FL + D IIV+KNG ++ESG+Y+ L+ + F++FLI Y + + ++ D+ +K L +T + E R+ + + + S + D+L E ++DL IEEEK +G + +Y Y + G + FF ++F + AN WLS+W+ A T YL +Y +G Q I + + AS IH KLL+ V+R+P++FFDTNP GRI+NRFS DID +P + +I +F+ L IV++C + P F +I+P + Y +Q+F++ ++Q+KR ES+++S I++HF+ET+TG+ +IRA+ F+ E+ ++ C F V ++RWL +R+E LGN++V F A+F++ SR PG+ GLS++YAL + LN +I + ++ETN V++ERI EY + EA +DLP DP WP G + F +Y TRYR GLDLVLKGI+ ++ EKIGI GRTGAGKSSLTL+LFRIIE +G I IDG++I LGL LRSRITIIPQDP+LF+G+LR NLDP E +D +IW AL+++HLK + +L GL + EGG N SVGQRQLICLARA+LRKT+ILVLDEATAA+DL TDDLIQSTIR EF+ TV+TIAHR+NTI+D +RI V G IAEF P LLANP S ++ ND+
Sbjct: 21 MGTSTFCSDPLWNSNLTWYTEDPYFTDCFISTVLVYVPSGILFLLTP-----YEIWTCFNLGENSSRISRTWL---NFSRTILVGFLILLSLVEFIF---ELLREDNVLSNIVAPGIYFLTFLNVFILQI-LGRIKGRVSSGPLFVFWL----LEVFAAGFSFRNWRNIHRVPNTDLVTLSTIVIQY-PVVVILLFMGFWADGNNNYNKIGDNDLNPSSLRMASFTSKLTFSWFDPFIYKA------WKKXVTDDDLYEINDEFKSCGVLPSWDREMEKEIRRKHLKNKPINILWP-LVRSFKSTLLASSALQFFYSVFQFGAPQLVDLIINFVSDPKEPIWKGYLYLFAICSITFINTLIYSQSNYYSYITGLKIRTSLTSSIFNKAVNLKSSSKKQMSVGETTNLMAIDSQRLMDFCLYIDMIWSSPLKIIIAMYLLWQVLGPASLAGLAVMILLIPINIVVGKKVKKFTAIQMQNKDKRIKLMDDILNGIKVLKLYAWEPSFIDAVTNFRVQEIGALKKSALINAVTSFMWTSAPFLVALASFTTYVLIDEKNILTPSTAFVSLTLFNLLRLPLNLLPMMIMKAIQSKVSLDRINLFLNKEDLDLLAISHESQ--GSHAVKMCNVSLSWETDEGLNT-LEDIDLDIEKGSLVAIVGQVGSGKSSLLSGILGEMEIVRGSINVDGQTIYAPQQPWLQNETLRNNILFGKRFNKKLYRRVIDACALSPDLDMLPAGDLTEIGERGINLSGGQKARVSLARCTXNNGDIYILDDPLSAVDVHVGRHLFENVISSQTGLLKNKTRIFVTHGAIFLPQTDKIIVMKNGVISESGTYRDLIEKENGEFAQFLINYLVDEKENILKNDQDLKTIIKDLESTVGGSEELEKRLEAAQSDKSTALTDLIQGTKYLDENTSDQCSSIASRKGEDDLDEVVSNDLNERLIEEEKIESGGIKLNIYLNYFKRTGLLASFFGILFYFSYQGFSLG-ANLWLSKWSTDRAAINSTSI--RNHYLEIYAILGFFQSIFTMLGSVTIAIGTLNASMKIHGKLLENVLRAPLSFFDTNPLGRILNRFSKDIDVAXTTLPFNIRMMIAQSFNVLGTIVIICIALPWFFVIILPAVICYALIQKFYISCARQVKRIESISRSPIYSHFAETLTGIPTIRAFGMVHHFIDENVNKIDFNAKCYFPTVISSRWLAVRLETLGNILVIFVALFSITSRGTTDPGMVGLSLSYALSVTTILNMLITVSTDVETNMVSVERIKEYENIPQEAPYDLPNSDPP--PNWPEHGVIKFDNYKTRYRKGLDLVLKGINCTIQKGEKIGIVGRTGAGKSSLTLALFRIIEPSEGSIYIDGENIRFLGLGKLRSRITIIPQDPILFSGSLRMNLDPFEAFADRDIWIALEYSHLKSFVWNLGDGLNFSVLEGGRNLSVGQRQLICLARAILRKTQILVLDEATAAIDLETDDLIQSTIRSEFKDSTVLTIAHRINTIMDSNRIMVLDAGTIAEFDDPQNLLANPDSMFYSLVNDSN 1517
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000003611 (supercontig:LSalAtl2s:LSalAtl2s197:49356:53594:-1 gene:EMLSAG00000003611 transcript:EMLSAT00000003611 description:"augustus_masked-LSalAtl2s197-processed-gene-0.4") HSP 1 Score: 990.719 bits (2560), Expect = 0.000e+0 Identity = 530/1275 (41.57%), Postives = 774/1275 (60.71%), Query Frame = 0
Query: 208 ASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRKQAEDKLVDFTSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHMDS----NEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPH-----AIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDELKVLATTTKEPPKREVRVPSEEVESPEETDNLIEETADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
AS SLL + W+ LLW+G K P+ +L + + + + + + K K+ P L K G+ +I + F +L V PQI+KL+I H DS E W+G+ Y +L+ S L ++ Y + + + ++++R SL +Y+K L+LSN +R+ SVGE+ N MSVD RI + P++ L SP I++++ F++ EL A + G + I IP+N S KK Q++Q++AKD R K++NE+L GI++LKLYAWE ++ +I IR EI I+K L +F+ F + S+P +V + F +V +D ++LTA+K FV + N M+ P+ FPF ++ ++ VSLKRIN+ L + E+ V ++ AI + + W ++D + LS +NL I GSLTAIVGTVG+GKSSL+S+ LGEM K SG+V+++G IAYVPQ++W+QN +L++NILF + + Y +V+ C L DL++L D TEIGE GINLSGGQ+QR+SLARA+YSDAD+Y+ D+PLSA+D+ VGK++F VL++ G +KDKTR+LVTH +++L + +I V+ G++ G+YQ+LL + + E PK + + T N +E+ A +I++E GRV VY Y+QSIG F ++F L + ++ WL W + + R YLGVYG +G+ Q + F L M +ASKVIH++ +MR+P++FFD+ P GRI+NRFS DI D ++ + + + C F L +++++ S P+F +P L++ +Q +V S+Q+KR +SVT+S I++HFSE++ GL+SIRAY Q +F+ ES ++ C + ++ ANRWL +R+E +GNL +F AI + + E + PG GL I+YAL + LNW+ R E+ETN VA+ER+ EY + E EW L D + WP++G V FK+Y+ RY+ DLVLK I+ + E++GI GRTGAGKSSL+++LFRI+EA G+ILIDG+DI+ LGLH LR +T+IPQ+P+LF+G LR NLDP SD +IW+ L HLK +I DLK GL H ISEGG N S GQRQL+CLARALLR KIL+LDEATAAVD TD+ IQ TIR F CT++TIAHRL TI+D D+I V G + EFGSP EL N S +M N AG+
Sbjct: 160 ASFFSLLFYEWITPLLWKGFKKPITEDDLWNLNKDLTCGETSRRLDQYYFKSGNKKI---GIP----------LMKAFGFEFVIGSTIKFFSDILSMVLPQIMKLMINHADSEFEMKERSWKGYLYPSMLIIVSFLQSVLLAKYFEIVFLVSMRIRASLTSLVYRKCLKLSNSSRKNKSVGEIVNIMSVDVSRIADLMPFLTLLWSSPFQIVVSVIFMYNELGWAIIGGTGILLITIPVNAILSYFGKKFQMKQMKAKDNRTKILNEVLGGIRILKLYAWEPSYINKIEGIRGVEIGILKKAAWLTSFMGFIWSSTPFIVALASFATFVMVDDRNILTAEKAFVTQSYINKMKMPMAXFPFVIVXAISATVSLKRINQLLTSDELQKDAVERVPMKINQKIDQGDAIVIRDGNFKWSTEDS-ENTLSNINLRIKHGSLTAIVGTVGSGKSSLISAILGEMVKKSGKVRIKGQIAYVPQESWMQNTSLKNNILFGKPYDEEWYNQVLEYCCLTYDLSLLPAGDETEIGERGINLSGGQRQRISLARAIYSDADVYIFDNPLSALDSQVGKSVFNNVLNNNTGIIKDKTRLLVTHGISYLPHVHHIAVMLKGEIIHEGTYQELLEKKIIQTIEEEEEQEKDGVQENN-------INNYNNIPK-----------TFDATVNNLEKAA--IIQKEGLETGRVSWSVYKYYIQSIGFLGAFLIIFNQMLNQLFGFGSSIWLEAWTQEDYGNATIPKYRD-LYLGVYGALGIGQAVTIFLLSLSVAMFTLKASKVIHNQTYDRIMRAPISFFDSTPQGRILNRFSKDISICDNILGSNIRQWLXCLFXFLGIVILIVSVLPLFLLFALPTSLVFILIQNIYVASSRQLKRLQSVTRSPIYSHFSESLNGLSSIRAYGAQSKFILESINKIDTNQRCNYPSIIANRWLAMRLETIGNLCIFGXAILTMTNPELVGPGKVGLVISYALILTQNLNWLXRQTSEIETNIVAVERLKEYAGLDIEKEWRLHKD--TSYNWPSQGKVEFKNYSLRYKANSDLVLKKINFTIFGGERVGIVGRTGAGKSSLSVALFRIVEAANGQILIDGKDISTLGLHDLRESLTVIPQEPLLFSGTLRSNLDPENAFSDHDIWNTLGSVHLKEYIRDLKDGLNHSISEGGLNLSSGQRQLMCLARALLRSCKILILDEATAAVDWETDEKIQETIRCYFPSCTILTIAHRLKTIIDYDKILVLDKGTVIEFGSPNELYMNSDSVFHSMINAAGI 1397
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000011700 (supercontig:LSalAtl2s:LSalAtl2s812:79332:86643:-1 gene:EMLSAG00000011700 transcript:EMLSAT00000011700 description:"maker-LSalAtl2s812-augustus-gene-0.6") HSP 1 Score: 922.154 bits (2382), Expect = 0.000e+0 Identity = 503/1322 (38.05%), Postives = 797/1322 (60.29%), Query Frame = 0
Query: 169 VEEWVLLITYVPIILGLFIAHCWVDIDPRAAEDLSLEDKASCL-----------SLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRK-QAEDKLVDFTSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHMDSNE-PVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDP-THVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEM---EKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDELKVLATTTKEPPKREVRVPSEEVESPEETDNLIEETADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
+EE + I +V ++L +AH W + PR +E + L C S + FSW+ L+W+G K P+K K+L S+N F K W K + K ++ + P S++P L +++ L L LL SP +++ LI S + P+ QG +++L + +L T Y ++ ++++ S+ +Y+K+LR+ + R + GE+ N MSVD Q+IV+ P + + PL I+ A+Y L L ++LAG++V + IPIN F + +K Q++Q++ KD R+K MNE+L GIK++KLYAWE F + I IR EIK++K+ + + F+ + S+ +++ F +YV DP H+L ++KIFV+I+LFN++R PL + VSLKRIN+FL + E++ ++ +N AI + ++ + + +++ + G+L AI+G VG+GKSSL+S+ LGEM K + V++ GS+AY PQ AW+QN++++DNILF ++F+ Y +V++ C LE D+ D TEIGE GINLSGGQKQR+SLARAVYS +DIY LDDPL+ VD+HV K +F +V+ S G L+ KTR+LVTHN++FL +D I LK+G++ E G+Y++L+ FSE + + +N +T++ +D KV+ +E K+ + ET + +EE G+VG +VYW ++ IG + ++ ++ ++ WLS W+D + +D ++LG+Y G+GV + + + L+ +S AS+++H L Q ++++PM+FFDT P GRI+NRF DI+ +D + + + F ++ + ++ + PIF + + ++YF + + S+Q+KR SV S I++HF ET++G+ ++RAY + F E + R+ + F + A+RWLG+R+ ++GN ++F +A+F+VLSR+ ++PG GL+++ +L I L+W+IRM +LE N VA+ERI EY++ ESEA W+L D K+ +WP +G ++ K+ + +YR LD VL+ I++ + +KIGI GRTG+GKS+L L+LFR++E G+I IDG DI ++GLHTLRS++TIIPQDP LF+G LR NLDP + D E+ +L HA+L+ + + GL I+E GEN S+GQRQLICLARALLRK K+L++DEATAAVD TD LIQ I+ F TV+TIAHRL T+LD +I V G I E+ SP LL++ +S M ++G+
Sbjct: 700 LEELMSSIIHVTLLLLNVLAHFWPEPPPRYSEYVRLVGVEGCHNPSPDTQCGYPSYIFFSWMSSLMWKGFKRPIKQKDLWDFIPSVNTALVNPHFLKHWNKIYTQTKFSNYPTSKSP--SIFPALLRSYWPLLLKGAFAKLLHDLLLICSPMLLQYLILFSYSPDIPLGQGIALSVILFGNKILGTFFIARYFFYMVTVGMKLKTSITSLIYRKALRI-HSTRDDTTSGEIVNLMSVDVQKIVDLMPLLNTIWSGPLQIIAAIYLLINTLGYSALAGVLVMFLLIPINGFIAVRMKNAQMKQMKKKDERVKKMNEILQGIKIIKLYAWESSFSKLISSIRFEEIKLLKLSSKYFGFMMLTISSTTFFISLFTFIVYVVSDPENHILDSEKIFVSISLFNILRFPLNMLTHVIGGIASASVSLKRINKFLASEELEE-GILVRSNSHDHQAI-CIHPSSSFSWKGSSESLFKDISMDVNRGNLIAIIGPVGSGKSSLISALLGEMLFTSKGTNPVEIHGSVAYTPQNAWMQNVSVKDNILFGRKFNKNWYDEVLKACSLESDMEXFPSGDSTEIGEKGINLSGGQKQRISLARAVYSQSDIYFLDDPLAXVDSHVAKHLFEEVIGSN-GLLRGKTRILVTHNLSFLHLVDEIYFLKDGEITEKGTYKELMEKNCDFSELISNHANNKITNQ--SDSEKVMEKINEEGTKQPI------------------ETNFKIYDEETLHTGQVGIRVYWYFLSKIGMLAGILAFSFFIISQILATGSSVWLSVWSD-----AKNNTD-IYYHLGIYAGLGVSNIFISTAGTLILSLSLLDASRILHGTLFQCIIKTPMSFFDTTPLGRILNRFGQDIEVLDTKMSFCIFGSMTGTFAYIATVTIISINVPIFIIPTLAIFVVYFVILIVSLSSSRQLKRLSSVATSPIYSHFGETLSGINTVRAYSLEKAFYSEFERRLDEYQKRNFPVIMADRWLGIRINLIGNFIIFASALFSVLSRDTITPGQLGLNVSSSLAITSILSWVIRMYSDLENNIVAVERIKEYSNKESEAPWELEEDLKLNSSWPLKGEITIKNLSLKYRKDLDWVLRDINVHISPGDKIGIVGRTGSGKSTLALALFRLLEVNSGQITIDGVDIKKMGLHTLRSKLTIIPQDPTLFSGTLRLNLDPFGLFKDMELIESLKHAYLQDFLKE--DGLDKVIAENGENISLGQRQLICLARALLRKNKVLIMDEATAAVDSETDKLIQKAIKDNFRDSTVLTIAHRLQTVLDYSKIIVIDSGCIIEYDSPKNLLSDSSSTFYKMCLNSGI 1987
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000001655 (supercontig:LSalAtl2s:LSalAtl2s128:1836948:1854487:1 gene:EMLSAG00000001655 transcript:EMLSAT00000001655 description:"augustus_masked-LSalAtl2s128-processed-gene-18.4") HSP 1 Score: 681.019 bits (1756), Expect = 0.000e+0 Identity = 403/1179 (34.18%), Postives = 634/1179 (53.77%), Query Frame = 0
Query: 304 FVSPQIIKLLIKHM-DSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHA----------IEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVR---GSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDELKVLATTTKEPPKREVRVPSEEVESPEETDNLIEETADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDL-KLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAM 1467
F P ++ L+K M D + G+FY L S+ L + + ++ +++R S++ +LY+++L +S YS GE+ N+MS+D R+V P P +++ +Y L ++ V+S G+ + IPIN + + L + AKD R+K++ E++ GI+V+K Y WE F + R EI +K L A + + S+P+++++ F Y A+ + LTA K+F ++ALF ++ P +FPF + ++ VS+KR+ FL+ I+ D + A I++ EA+ + D L +++SI ++G VG+GK++ L++ LGE+EK SG++ VR IAYV Q WIQN ++RDNILF + + YTKVI+ C L+ D L D T GE G LSGGQK R++LARA+Y D DIYL+DD S++D +VG ++T+V+ LK KTR+L THN +++ + +I +K+G E + + +T P S + + DN DD +EEE G V ++Y Y Q+IGT T++ L V + WLS W + T + T Y+ VY G+ V IL R L A+K+IHD LL ++R+ + FFD+ P GRI+NRFSSD +D +P L+ + F ++V + P V++PLGL Y+ +Q + S+ +KR SV+ S I+ HF+ET+ GL IRA + RFL E++ V+ + SA+ WL +R++++G++VVF A+ +V++ E++ G+ GL+++YALG+ L ++ E E VA+ER +Y E + L+ + + WP +G V FK RY++ L VL ++ + + EKIGI GRTGAGKSSL +LFR+ G I++DG I L L R + +IPQDP +F+G +R NLDP HSD E+W ++ ++L I GL I +GG++ S+GQ+QL+CLARA++ K++ +DEATA+VD TD LI++ ++ F TVITIAHR+ T+L+ DRI V S+GQI E G P +L+ +P S + +
Sbjct: 324 FFCPLLLNRLVKFMEDPKADLRWGYFYAFSLFVSTFLVAICNTQFNFKMNELGLKVRASVIQSLYKQTLSVSEANLNKYSRGEIINFMSIDVDRVVNFAPSFHAFWSLPFQMVVTLYLLHQQVGVSSFVGVGFAILMIPINKVIATKIGSLSGHMMSAKDDRVKIIAEIIEGIRVIKYYCWESFFTDKTNSHRNNEIYYLKWRKYLDAVCVYLWASTPVIISVSTFATYSALG--NPLTAAKVFTSMALFAMLSGPFNAFPFVINGLIEANVSIKRLARFLSLPSINRIKYFTEYKDENTKASKEIETKIPDIQIMEASFGFTKDCFT---LRNIDVSIKRQEFVGVLGPVGSGKTTFLNAILGELEKQSGKISVRDPLSGIAYVQQVPWIQNKSIRDNILFGEMYIHGKYTKVIKACCLDHDFKHLHRGDHTIAGEKGAALSGGQKARIALARAIYQDKDIYLIDDVFSSLDVNVGYKVYTEVM---LNLLKRKTRILCTHNPQYINDANIVIKIKDG-------------------------------------EFESVKQSTHLVPTSTSPDFSYDTSMFDFKDN--SNVIDDSVEEEMQETGVVAYRIYKKYWQAIGTYLAPTILISIFLMQVASNTTDLWLSHWVSTDNFQNNT--EDTDHYIYVYSGLAVFHTILTLIRAFLFAYGGIHAAKIIHDLLLGVLLRAKIYFFDSTPAGRILNRFSSDTYAIDDSLPFILNIFLSQIFGVFGRVLVCVYAVPWILIVLLPLGLFYYEIQCKYRPGSRDLKRISSVSLSPIYEHFNETVHGLKIIRASKASQRFLLENEELVECNQKARYAAFSASLWLEIRLQLIGSIVVFSIALISVINFESVDAGLVGLAVSYALGMTXRLAEVVVSFTETEKELVAVERAYDYIDRIYEESYSGVLN--MPYNWPNQGVVEFKDIRLRYKDHLPYVLNKVNFKTKPKEKIGIVGRTGAGKSSLIAALFRLSSFSHGEIMVDGIRIRLLPLIDFRRQFAVIPQDPFIFSGTIRQNLDPYAQHSDQELWDSIKLSYLYNIIYSFGSSGLDTLIGDGGKSLSIGQKQLLCLARAIITSAKVVFIDEATASVDKETDRLIRNVLKTAFNDKTVITIAHRIETVLNSDRIFVMSNGQIIEEGKPEDLIKSPNSEFRKL 1451
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000000752 (supercontig:LSalAtl2s:LSalAtl2s111:55855:93761:1 gene:EMLSAG00000000752 transcript:EMLSAT00000000752 description:"maker-LSalAtl2s111-augustus-gene-1.10") HSP 1 Score: 595.119 bits (1533), Expect = 0.000e+0 Identity = 400/1319 (30.33%), Postives = 657/1319 (49.81%), Query Frame = 0
Query: 210 CLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRKQAEDKLVDFTSPIRPFVSLWPILFKNHGWRALIALIVALFR-VLLPFVSPQIIKLLIKHMDSNEPVW---QGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSF-PFTLIESVKVFVSLKRINEFLNASEI----DSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLK-NGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDELKVLAT------TTKEPPKREVR---------VPSEEVESPEETDNLIEETADD---LIEEEKTVAGRVGAKVYWTY-VQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLH-------------------------IMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTH--NESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAG 1472
C +++ W + +G K +L K+ R + K+W+K+ K+ F+ P S + + L++ LF +L P I +I + S + +F++ +L+ + ++ + Y + +Q+R + +Y+K+L LS + S+G+M N +S D R + ++ L ++P+ + M + ++AG + FI + K KL++ D R+++MNE+L GIKV+K+YAWE PF++ + R + + P+ + + +FG+ + A KIF+ LF+ ++ PL F P + S + VS+KRI EFL +E+ N + P +E+T+ + W D + L ++ S+ G L AI+G VG GKS+++ S LGE G++ ++G I+Y Q+AWI + ++R NIL + Y +VIR C LE D+ D T +GE GI+LSGGQK R++LAR VY+ ADIY+LDDPLSAVD HVG+ +F + + L DKT +LVTH + FL +NII+L +G++ SG+Y+KL++ F +L + TS S++ +D L + + + K+ K+ VR VP + E D EE + +E + G V +Y Y V G +F V FL + + ++++WL W + +A + G FY Y + +Q+ DF + + MSC ++S+ +HD++ + V + FFD NP GRI+NRFS DI D+++P L + +++ + P+ I+ L LI ++++++ S+ +KR E +T+S +F+ + ++ GL +IR+ + ++ + E T+ + + NR+ +++ +L + + + G GLS+T +L + + W +R E+E ++ER+ EY E + D+ LDP +WP +G + F + +Y VLKG + +G+I IDG +I +L L +R +I+IIPQDP+LF G +R NLDP + + + IW AL+ A L +S+L+ GL E+SEGG NFSVGQRQL CLARA+LRK K+L++DEATA VD +TD LIQ IR EF+ CTV TIAHRL T++D DRI V S G+I E G+P +LL++P++ M N G
Sbjct: 341 CKAIIFIKWTIPFIRKGQKEDFDVHDLYKTLREDYSRELNDRLEKEWQKELS-KVKTFSGNYHP--SFAKAAIRTFRLQTLLSGXFVLFEECVLRIAQPFAIFKIIGYFSSGGTXMSEXELYFWSGILVGAGVIFVLFDQRYWYLSLKTGMQLRIAASAIIYRKALTLSKASLGRSSIGQMVNLLSNDVNRFDNSTVFLQYLWVAPIQFICVMLITSYFAGIEAVAGGALLIFFIFFQTYMGKMFSKLRLMTASKTDIRIQIMNEILDGIKVIKMYAWETPFVQLVTNARNRFVLL------------------PVFLLMVLFGVEI--------NAQKIFLIFGLFDAIKLPLTHFFPSAISASSEALVSMKRIEEFLLLNELRDVQSKINHVILPGRYEPLTVEVTKISGKW-LDSSNEFTLKNISFSVEIGELCAIIGPVGCGKSTIIQSLLGEFPVSYGEINIKGRISYASQEAWIFSGSVRQNILMGKPLIDKRYREVIRVCALEHDVREWPDGDYTFVGEKGISLSGGQKSRINLARCVYASADIYILDDPLSAVDPHVGQQLFDTCI---QKFLSDKTVILVTHQLQFLKNANNIILLNSDGEIEASGTYEKLMSQS-GFVTYL-EATSEEEDSDLLSDVLSDVKSDGEYMRSQKKKLKKGVRSRRSSTSLLVPVPYIGGSTERDTFPEEKGSQEWKMGSKETIIEGSVSLSLYHKYFVAGGGFFKFLCVYFLSLITHTLFVVSDWWLRLWTNAADAR-KLGPLPPTFYFSEYQDM-TLQITADFQVDFFNFIYCSIYLSLIIILLFSAQLSVRQLFMSCMRSSQTLHDRMFEKVAFTNSRFFDLNPNGRILNRFSKDIGSXDELLPPAL-------LSGSGIFILISMTNPLIVVGIVVLLLILLTIRKYYLNASRAVKRLEGITRSPVFSQLASSLDGLTTIRSMKIEEMLIEEFDYLQDIHTSSYYSFLVVNRFFAFCGDLMLSLFTASMVSMFLFYNRDATGGDVGLSLTLSLALCGMIQWGLRQSAEVENFMTSVERVAEYGDLPKEKGLKGDIKLDP----SWPDKGVIEFSNVNLKYDGTTPYVLKG-------------------------------LTEPEGKIFIDGVNICRLSLQDVRKKISIIPQDPLLFKGTIRKNLDPFDEYGELAIWHALEQAKLSVAVSELEGGLETEVSEGGNNFSVGQRQLFCLARAILRKNKVLIMDEATANVDPMTDSLIQEAIRTEFKDCTVFTIAHRLYTVMDSDRILVMSDGEIKELGAPLDLLSDPSNIFYQMVNQLG 1580 HSP 2 Score: 231.106 bits (588), Expect = 2.030e-61 Identity = 126/285 (44.21%), Postives = 170/285 (59.65%), Query Frame = 0
Query: 1185 LNWMIRMLCELETNSVALERILEYTH--NESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAM 1467
+ W +R E+E ++ER++EY E E D+ LDP +WP +G V F + + RY VLKG++ + S EKIGI GRTGAGKSS+ +LFR+ E +G I IDG DI ++GL +R +I+IIPQDP+LF G++R NLDP +D +IW+AL+ A L + DL GL + E G NFSVGQRQL CLA A+LR+ K+L++DEATA VD TD LIQ IR+EF+ CT EFG+P +LL +P + L M
Sbjct: 2 IQWGLRQSAEVENFMTSVERVVEYGELPKEKGLESDIKLDP----SWPDKGVVEFSNVSMRYSQHQPNVLKGLNFKTNSFEKIGIIGRTGAGKSSIISALFRLAEP-EGEIFIDGLDICKVGLLDIRKKISIIPQDPILFNGSIRKNLDPFNEFTDVQIWNALEQAKLYDIVVDLGHGLDSVVLEFGSNFSVGQRQLFCLAXAILRRNKVLIMDEATANVDPFTDSLIQEAIRKEFKDCT--------------------------EFGTPKDLLKDPNNLLSRM 255 HSP 3 Score: 53.9138 bits (128), Expect = 3.366e-7 Identity = 52/194 (26.80%), Postives = 85/194 (43.81%), Query Frame = 0
Query: 623 ILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSF--LGEMEK----------LSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAV----DAHVGKAIFTQVLDSTE-GCLKDKTRVLVTHNVNFLDKM 799
+L +N I+G GAGKSS++S+ L E E G + +R I+ +PQ + N ++R N+ EF+ + +L + L H + + E G N S GQ+Q LA A+ + ++D+ + V D+ + +AI + D TE G KD L+ N L +M
Sbjct: 66 VLKGLNFKTNSFEKIGIIGRTGAGKSSIISALFRLAEPEGEIFIDGLDICKVGLLDIRKKISIIPQDPILFNGSIRKNLDPFNEFTDVQIWNALEQAKLYDIVVDLGHGLDSVVLEFGSNFSVGQRQLFCLAXAILRRNKVLIMDEATANVDPFTDSLIQEAIRKEFKDCTEFGTPKD----LLKDPNNLLSRM 255
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000000090 (supercontig:LSalAtl2s:LSalAtl2s1014:9799:23913:-1 gene:EMLSAG00000000090 transcript:EMLSAT00000000090 description:"maker-LSalAtl2s1014-snap-gene-0.6") HSP 1 Score: 418.698 bits (1075), Expect = 5.973e-128 Identity = 294/952 (30.88%), Postives = 471/952 (49.47%), Query Frame = 0
Query: 555 MRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSP-------HAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEM-EKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDELKVLATTTK----EPPKREVRVPSEEVESPEETDNLIEETAD--DLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWA--------DHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVII-PLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSET-ITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVL-GNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVG--HTWPTEGA-----------VSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSR-ITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAM 1467
MR P P + + VS+KRI+ +LN E+DS +ND S ++I++ + + D +L +N S G LTA+VG VG+GKS LL++ GE+ ++ G + + YV Q W+++ T+RDNI F Q ++S+ Y KV+ CQL D + D T + NG LSGGQ+QR+ ARA+Y +A +YL+DDPLSA D+++ IF + +G L+ KTR+L+T+ + + MD IIV++NG V E S + EV++ E+ +T + EPPK DN + D D+IE K + +Y YV ++GT F + Y ++ + WLSRW D N H D Y+ VYG +G Q + F LL +AS HD +L+ V +P+ FF + P G I+NRFS D+D D +P L + + A L +++ + PI A I+ PLGLI+ V + +++ S+ +KR + + + HF ++ + G +IR Y + ++ E + + + + + + + + L LR++++ G + A E S ++ LS+T +L ++ + R +E V++ERI E E +P DP G + T G+ + F+ ++ +Y + + +K + VR EK+G+ GRTG+GKSSL L+L ++E KG+I IDG D++ +R + IT D LF G++R+NLDP++ +D IWS LD A +K L GL + E G N S+ LI ++DEA +A+ L +++ I +T F T+ IAHR+ +L CD+I V +G IAEFG+P L+ + S K+M
Sbjct: 1 MRIPFRLLPSCISALSQGIVSIKRIDSYLNREEVDSVK----SNDFSKSPRPEDGYSIQVQDCNYSIDKL----KLLKNINFSTRVGELTAVVGKVGSGKSCLLAALCGELNQRGKGSSLINKDLVYVTQNIWLKSATIRDNITFGQPYNSSQYQKVVSLCQLGQDFKDMYRGDLTYLASNGSTLSGGQRQRIGFARAIYQNAQVYLMDDPLSACDSNLKAQIFHNTI-GPKGFLQKKTRLLITNQSSLIPLMDRIIVIQNGTVEEKDSAE-----------------------EVKSFEIAKKSTKKQGSFHEPPK----------------DNYLHPALDNYDIIERRK-----IPFSLYKYYVLNLGTVPFIIALVGYLISQCFDVCSKLWLSRWTNLSSTNINDTNYRHI-YNEDTRNMYIVVYGILGWCQSLAYFLSVLLINSRSLKASSHFHDVILRKVFGAPLNFFWSTPKGTIINRFSKDMDEADMFLPNTLKNFAYQAVKILGTLIIALIAFPITAFFIVCPLGLIFIEVVKSYLMASRFLKRTSATKLAMVLKHFGDSAVHGGTTIRCYGVESDYIDEHMSLIDEHQSVSLMEIISEAXLFLRLQLIAGTFIGILATALVFFPSEGNSSSLSALSLTSSLTVLQDIFLFTRYAAFIEKAMVSIERI-------KECEDLIPQDPSSGLLPSIITNGSKRPKNHQSRYYIQFEDFSGKYSSLKNASIKNFTLNVRLGEKVGVVGRTGSGKSSLILALSGLLEVEKGKIFIDGVDMSSGTARNIRKKDIT----DAALFKGSIRYNLDPDDRFTDEYIWSVLDEAQMKEFFVQLPGGLDFSLKENGSNISLAGSNLI-------------IMDEAXSAMTLESEERILNTYFSRFSSSTIFVIAHRIQPLLACDKILVLENGTIAEFGNPESLIKSQKSIFKSM 874
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000000741 (supercontig:LSalAtl2s:LSalAtl2s111:116041:261433:1 gene:EMLSAG00000000741 transcript:EMLSAT00000000741 description:"maker-LSalAtl2s111-snap-gene-2.14") HSP 1 Score: 392.119 bits (1006), Expect = 1.905e-112 Identity = 286/923 (30.99%), Postives = 464/923 (50.27%), Query Frame = 0
Query: 192 VDIDPRAAEDLSLEDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKS---PRSMNVTDNVKAFTKQWRKQAEDKL-VDFTSPIRPFVSLWPILFKNHG-----WRALIALIVALFRVLLPFVSPQIIKLLIKHMDSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAF-INFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPL-VSFPFTLIESVKVFVSLKRINEFLNASEI-DSTNVIHTANDLSPHA---IEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLK-NGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDEL---KVLATTTKEP-------PKREVRVPSEEVESPEETD----NLIEETADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYG---LASVVHALANYWLSRWADHNEAHPETGSDRTGF--------------YLGVYGG-IGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLI 1066
+DI+ + + A+ LS + F W+ LL G +LP + +S ++DN++ ++W+K+ E L D TS R SL L + G + A + +FR+L P QI+ P Q + ++ VL+ S +L + H Y + +++R + LY+KSL+LS + SVG+M N +S D R ++ L ++PL ++ + + ++S+ G + +FIP+ + K +L++ D R+++MNE++ G+KV+K+YAWE PFM + E R EI+ IK AF + F + SS +++ + F + + V+++ IF+ LFN +R L + FP T+ + + VS RI FL EI D + + ++ P IEM + W S++ D L ++ + LTAI+G VG+GKS++L + LGE SG + + G I+Y Q+ WI + T+R NIL + Y KV++ C LE DL RD T +GE G+ LSGGQK R++LAR+VYS+AD+YLLDDPLSAVD+HVG+ ++ + + + L KT +LVTH + +L NII+L G++ + G+ KLL + F+ FL V E ETD + LA T K+ +R+ V S + +T+ N I E V G + +Y Y + G F F+YG L+ ++ ++WL +W + +A ++ + F Y G+Y +G + + S I+ C ++SK +H ++ Q V+ + AFFD NP GRI+NRFS DI +D ++P LSD + + + ++ S+ P V+IPLGLI
Sbjct: 1 MDIEEKVNLKDNKRSNANILSKIFFIWVLPLLRDGQNKAFDIPDLPSALTEDKSRYLSDNLE---REWKKELEKGLRYDNTSKKRYSPSLLRALIRTFGSSLGVYGAFSFIEECVFRLLQPLAISQIVLYFSNSNHGISPT-QLYIWSAVLIMSGVLYVFSHHWYFFGVVQVGMRIRIACSALLYKKSLKLSKASIGKSSVGQMVNLLSNDVNRYDLCVLFIHYLWVAPLQFILVSIITWYMVGISSMCGGAILLVFIPLQTWIGKQFSRLRILIAGKTDKRIRVMNEIIEGMKVIKMYAWEYPFMEVVNETRRDEIQTIKKTYEYKAFNLGFFFTSSRVVLLLIFFLMIIG---NEVISSKNIFLIFGLFNTVRLSLTLFFPNTISMTSEALVSTDRIQNFLLLEEIGDICSSMKHEPEVRPEVSLRIEMKNVSGKWTSNEKDDD-LRNVSFQVHKRELTAIIGPVGSGKSTILQALLGEFPVSSGDISIYGKISYASQEPWIFSGTIRQNILLGASMNHKRYLKVLKVCSLEHDLESWPDRDHTFVGEKGVALSGGQKARINLARSVYSEADVYLLDDPLSAVDSHVGRHLYEECI---KNYLSRKTVILVTHQIQYLGDASNIILLNTKGEIEDQGTLNKLLMSERDFTSFL-------VAQEEETDSIFDEDELALTPKKSLNIENYMRRRQSSVSSIGSRATIDTNAMEYNDIPNEGRRTQTTESKVKGSISVALYKKYFYAGGGKWIF--FFVYGLNILSQLLFVSTDWWLKQWTNAADARTNNYANASSFEILPGFQIDLFNSIYYGIYFALVGALIICSQISIRKFLIL-CLKSSKNLHLEMFQKVIFTKPAFFDVNPVGRILNRFSKDIGSLDXLLPLALSDTSLIFLNAVGMFGLIISTEP---KVLIPLGLI 899 HSP 2 Score: 323.553 bits (828), Expect = 2.952e-90 Identity = 224/753 (29.75%), Postives = 369/753 (49.00%), Query Frame = 0
Query: 562 FPFTLIESVKVFVSLKRINEFLNASEI-DSTNVIHTANDLSPHA---IEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLK-NGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDEL---KVLATTTK-----EPPKREVRVPSEEVESPEETDNLIEETADDLIEEEKT------VAGRVGAKVYWTYVQSIGTSQFFTVVFLYGL---ASVVHALANYWLSRWADHNEAHPETGSDRT-GFYLGVYGGIGVVQLILDFSRELLH-------------------------IMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRN-GLDLVLKGIDMEVRSNEKI 1265
FP T+ + + VS RI FL EI D + + ++ P IEM + W S++ D L ++ + LTAI+G VG+GKS++L + LGE SG + + G I+Y Q+ WI + T+R NIL + Y KV++ C L+ DL RD T +GE G+ LSGGQK R++LAR+VYS+ D+YLLDDPLSAVD+HVG+ ++ + + + L KT +LVTH + +L + +NII+L G+ G+ KLL + F FL V E ETD + LA T + E R + + S D + E D E +T V G + +Y Y + G F F+YGL + ++ + ++W +W + +A + G R + Y +++ F +L + I C ++S+ +H ++ Q V+ + AFFD NP GRI+NRFS DI +D ++P LSD + + + ++ S+ P ++ + +I ++++++ S+ +KR E +TKS + + S T+ G+++IRA + ++ F E T F S R+ G V+ G + + A + N+ G G+S++ ++ + + W +R E+E ++ER+ EY SE L D K+ +WP +G + F + +Y + G +LKG+ + S EKI
Sbjct: 1154 FPNTISMTSEALVSTDRIQNFLLLEEIGDICSSMKHEPEVRPEESLRIEMKNVSGKWTSNEKDDD-LRNVSFQVHKRELTAIIGPVGSGKSTILQALLGEFPVSSGDISIYGKISYASQEPWIFSGTIRQNILLGAPMNHKRYLKVLKVCSLDHDLESWPDRDHTFVGEKGVALSGGQKARINLARSVYSEGDVYLLDDPLSAVDSHVGRYLYEECI---KKYLSRKTVILVTHQIQYLREANNIILLNTKGETEAQGTLNKLLMSERDFKPFL-------VAQEEETDSIFHKNELALTPRKSLNIENYMRRRQSSVSSIGSRATIDTNVMEYNDIPNEGRRTQTTESKVKGSISVALYKKYFYADGGKWMF--FFVYGLNISSQLIFVMTDWWXKQWTNAADARKKFGDIRNQKHFFSSYANTSSFEILPGFQIDLFNSIYYGIYFALVGALIICSQISVRKFIFLCLKSSRNLHSEMFQKVIFTKPAFFDVNPVGRILNRFSKDIGALDDLLPIALSDTNLIFLNAVGMSGLIISTEPKILIPLLAILIILLALRKYYLNASRSVKRLEGITKSPVISQLSTTLNGISTIRASKLENNFASEFHYLQDIHTAAFFSFQSVTRFFGFWVD--GIVSINVXATVVIFVFFNVKGGDIGISLSLSVLMARXIQWGLRQSAEVENYMTSVERVAEYGDLPSEKR--LTSDKKIDPSWPNKGVIKFHNVKLKYDDQGGPYILKGLTFTINSFEKI 1889 HSP 3 Score: 69.3218 bits (168), Expect = 7.492e-12 Identity = 64/271 (23.62%), Postives = 123/271 (45.39%), Query Frame = 0
Query: 214 LVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVK-AFTKQWRKQAEDKLV-DFTSPIRPFVSLWPILFKNHG-----WRALIALIVALFRVLLPFVSPQIIKLLIKHMDSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKV 477
L+ W+ LL G +L +SP S + + + + ++W+K+ E L+ D TS R SL L + G + + + +FR+L P QI+ P Q + ++ VL+ S +L + + H H + +SL+LS + SVG+M N +S D R ++ L ++PL ++ + + ++S+ G + +FIP+ ++ K + +L++ D R+++MNE++ GI +
Sbjct: 898 LIQRWVFPLLRDGQNKEFDTPDL-QSPLSEDKSRYLSDSLEREWKKELEKGLIYDNTSKKRYSPSLLRALIRTFGSSLGVYGPFVFMENCVFRILQPIAISQIVLYFSNSNHGISPT-QLYIWSAVLIMSGVL-----YVFSHHWHFFGMV-----------QSLKLSKASIGKSSVGQMVNLLSNDVNRYDLCVLFLHYLWVAPLQFILVSMIAWYMVGISSMCGGAILLVFIPLQIWIGKQLSRLRILIAGKTDKRIRVMNEIIEGISL 1150 HSP 4 Score: 63.1586 bits (152), Expect = 6.154e-10 Identity = 58/229 (25.33%), Postives = 96/229 (41.92%), Query Frame = 0
Query: 1246 NGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFN---------------LDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDL-VTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVF-SHGQIAEFGSPAELL 1457
N D L+ + +V E I G G+GKS+ I++A+ G + DI+ G +I+ Q+P +F+G +R N L + D E W DH + E G S GQ+ I LAR++ + + +LD+ +AVD V L + I+ TVI + H++ + D I + + G+I + G+ +LL
Sbjct: 434 NEKDDDLRNVSFQVHKRELTAIIGPVGSGKST-------ILQALLGEFPVSSGDISIYG------KISYASQEPWIFSGTIRQNILLGASMNHKRYLKVLKVCSLEHDLESWPDRDHTF---------------VGEKGVALSGGQKARINLARSVYSEADVYLLDDPLSAVDSHVGRHLYEECIKNYLSRKTVILVTHQIQYLGDASNIILLNTKGEIEDQGTLNKLL 634 HSP 5 Score: 59.3066 bits (142), Expect = 1.001e-8 Identity = 56/229 (24.45%), Postives = 96/229 (41.92%), Query Frame = 0
Query: 1246 NGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFN---------------LDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDL-VTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVF-SHGQIAEFGSPAELL 1457
N D L+ + +V E I G G+GKS+ I++A+ G + DI+ G +I+ Q+P +F+G +R N L + D E W DH + E G S GQ+ I LAR++ + + +LD+ +AVD V L + I++ TVI + H++ + + + I + + G+ G+ +LL
Sbjct: 1213 NEKDDDLRNVSFQVHKRELTAIIGPVGSGKST-------ILQALLGEFPVSSGDISIYG------KISYASQEPWIFSGTIRQNILLGAPMNHKRYLKVLKVCSLDHDLESWPDRDHTF---------------VGEKGVALSGGQKARINLARSVYSEGDVYLLDDPLSAVDSHVGRYLYEECIKKYLSRKTVILVTHQIQYLREANNIILLNTKGETEAQGTLNKLL 1413
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000002016 (supercontig:LSalAtl2s:LSalAtl2s1361:43077:48755:-1 gene:EMLSAG00000002016 transcript:EMLSAT00000002016 description:"augustus_masked-LSalAtl2s1361-processed-gene-0.2") HSP 1 Score: 317.005 bits (811), Expect = 4.236e-88 Identity = 189/598 (31.61%), Postives = 322/598 (53.85%), Query Frame = 0
Query: 915 FTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAI----FAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEW----------------------------DLPLDPKVGHTW---PTEG-AVSFKSY----ATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAG 1472
F V+ + L SV ++ L W+ E SD+ Y YG + V+ +++ L+ + A+A +H+ ++Q +M P+ F+ P GRI+NR S DI VDQ +P + +I +F ++ + +P+F +P+ IY+++ F+ S++++R +S+T++ + +HFS+T++GL ++RA+ +Q RF++E +V T+ + S RWLG+ ++ G + VF + + F RE S GLS+ Y+L + L W+++ +E A+ER+LEYTH SE E ++ D +V + +EG + F S + YR L + +G +E+ +K+GICGR+G+GKS+L + + R+ ++G I I+G +I + L LR + IPQD VLF+G +R NLDP SD IWS LD A + + GL ++E G+NFS+GQRQ + + +ALLR+ ++++LDE+T+A+D + + +T+ FE T+I++AHRL+ I++ +R+ V G+I E G+P ELL P A+ AG
Sbjct: 1297 FFVILSFVLQSV-KVYMDFLLRDWS-----MEEKNSDKLIAYFSFYGSLSVIVILISCVANLIGQLIGARARTKLHNDMIQNIMYCPLELFEAFPIGRIINRISHDIFIVDQKIPPCIQRLIMLSFVCIAALAXNSIQSPVFLIFALPMISIYWWLXHFYRRSSRELQRLDSITRAPVLSHFSDTLSGLITVRAFGEQTRFINELCEKVDTNTSAFLILQSGCRWLGVYLDAAGAIFVFLSILVNLFFPRKGREVTSSASIGLSVNYSLLVPIYLAWVVKFAANIENYMNAVERVLEYTHFPSEEEDFSEFQAVHASSMNSSRRSFLLRGRGKHDEIEEDVRVSGDFLQNDSEGLIIRFNSVCLAPSFEYRR-LPGIQQGFSLEIPYRQKVGICGRSGSGKSTLLMGIVRLSRVLQGSITINGININAIPLSRLRKFVITIPQDAVLFSGTIRSNLDPENDFSDELIWSTLDKADCGKTVRNFPDGLDTCVTENGDNFSLGQRQELNIVKALLRRPRVVILDESTSALDPNREVALHNTLLEAFEDSTLISVAHRLSNIVEYERVLVMGEGRILEDGNPKELLKKPMGFFSALWRAAG 1887 HSP 2 Score: 204.527 bits (519), Expect = 3.743e-53 Identity = 196/718 (27.30%), Postives = 337/718 (46.94%), Query Frame = 0
Query: 204 LEDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRKQAEDKLVDFTSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIK-----------HMDSNEPV--------WQGFFYT---------IVLLFSSLLSTMAFHAYQQHL-HISAIQMRNSLLGALYQKSLRL----SNKA---RRL----------------------YS------VGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVV-FAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPH---------------------------AIEMTEATLTWDSDDGVDP-----ILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQ--VRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLK-----DKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQ 817
L ++AS S L F WL+ +L QG++ PL+ +L K P+ + TK++ ++ + L S I LW + N + ++ + LF +L + I +++ H+ SN + + FF + +++F + L A HL +S I+ +N+L LY+KSL+L SN R++ YS +G +TN S D I E + + PL IL+ ++ L+ +L ++ ++G ++ + +P+ + K + + L ++D RL E L +K +KL E ++RI R E+ ++ LW+F+ F S LVT G++V ++ H TA +F ++AL + + L P T+ +K VS +R+ EFLN +E+ ++ N L+ H A + E T ++ P +L +NL I GSLT ++G G+GK++L+SS + EM++++G V+ V ++A + Q+ W+ N T++DNIL + F Y KVI C L+ D+ +L H D TEIGE G+ LSGGQ+QR+++AR +YS + +D P S++D+ + +F EG LK +T L T ++FL + D+I+ LK+G + G+ Q
Sbjct: 246 LYNEASSFSRLTFWWLNPILTQGYRAPLEIDDLHKLPK--------EERTKKYFQKLKTLLSRDKSSI-----LWECITMNWSF-VILGGLFRLFADILGYACALSINIIVNSIAAENENASLHLISNVTINPLKDTRYYDSFFVSELFFDPRVVSIVIFLAALGQGALSQTSNHLLTVSGIRAKNALHVLLYEKSLKLPVGSSNPMQIHRKINLKPLNDEGKGCMGGSCSLDEDYSNEGNIDIGFITNLASEDIINIRELIWNVHYIWALPLKILVLLFLLYDQLGISGVSGAILGTCVILPLQVLTGKLMSENNKLILCSQDNRLFKSTETLASMKTVKLATMEEWALKRIRCARTKELIFLRRDSFLWSFMAFLASISTTLVTTLTLGLFVLLE-DHNFTAADLFTSMALLSQLTVCLSVVPVTVPIFIKGKVSTQRLAEFLNRAEV---SIYKQNNKLNKHCTYFDDRKDDDEEEEEEEEESEIFIQRAKRLPETCFTVENGTFAWPKCETNVLQSINLEIKTGSLTIVIGPSGSGKTALISSLIEEMDRITGSVKWNVPDTVALLGQRPWLLNTTIKDNILLGRPFKEKRYKKVIAACDLQTDIDLLPHGDDTEIGERGVLLSGGQRQRLAIARCLYSKSYCTFMDAPFSSLDSKITSHVF------EEGVLKILLKRRRTVFLTTERLDFLHRADHIVALKDGMIKAQGTIQ 939 HSP 3 Score: 67.781 bits (164), Expect = 2.630e-11 Identity = 51/213 (23.94%), Postives = 97/213 (45.54%), Query Frame = 0
Query: 627 MNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRG-------------SIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAF 826
+L IP I G G+GKS+LL + L G + + G + +PQ A + + T+R N+ + +FS + + T + ENG N S GQ+Q +++ +A+ + +LD+ SA+D + A+ +L++ E D T + V H ++ + + + ++V+ G++ E G+ ++LL F
Sbjct: 1670 FSLEIPYRQKVGICGRSGSGKSTLLMGIVRLSRVLQGSITINGININAIPLSRLRKFVITIPQDAVLFSGTIRSNLDPENDFSDELIWSTLDKADCGKTVRNFPDGLDTCVTENGDNFSLGQRQELNIVKALLRRPRVVILDESTSALDPNREVALHNTLLEAFE----DSTLISVAHRLSNIVEYERVLVMGEGRILEDGNPKELLKKPMGF 1878
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Match: EMLSAG00000007660 (supercontig:LSalAtl2s:LSalAtl2s445:12562:17493:1 gene:EMLSAG00000007660 transcript:EMLSAT00000007660 description:"maker-LSalAtl2s445-augustus-gene-0.18") HSP 1 Score: 135.191 bits (339), Expect = 1.344e-32 Identity = 139/501 (27.74%), Postives = 221/501 (44.11%), Query Frame = 0
Query: 989 IHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFAS---VIIP---LGLIYF--FVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAV---------LSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVG------HTWPTEGAVSFK----SYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRIL-IDGQDIAQLGLHTLR-SRITIIPQDPVLFTG----NLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAEL 1456
+ L ++ +AFFD + TG IV+R S+D+ +S + + IV + +P S VI+P LG Y +++ Q+ +A +V + E I+ + ++R + +D + V K + N LGL + V FF + +S +NL+PG + I ++ + + L + RI EY +PL P G H++ G V FK SY TR VLK + + ++ + + G +G GK+++ L R + G L IDG +I L LR S I I Q+PVLF N+R+ PN +D E++ A AH+ + G + E G S GQ+Q I +ARALL+ IL+LDEAT+A+D ++ ++Q + + + T + IAHRL+TI + D IAV G +AE G+ A L
Sbjct: 188 LRKDLFNSIICQDIAFFDEHKTGEIVSRLSADVQEFKSSFKLVISQGLRSSAQASGCIVSMYMISPQMTSAMGVIVPTVILGGTYIGSYLRVLSKKAQAQVAKATAVGE--------ECISNIRTVRGFAMEDAEMELYSREVDKTRDF-------NEALGLGIGVFQGASNFFLNSIVLGTITYGGYLMSDDNLNPGQLMSFLVSVQTIQRSITQVSLLFGHLVKGMASGSRIFEYIEK-------VPLIPISGGVKIPYHSF--FGDVEFKNITFSYPTRPEQA---VLKDFSLRIPPSKTVALVGTSGGGKTTIAALLERFYDINGGGSLEIDGINIRDLDPSWLRGSAIGYINQEPVLFATSVIENIRYG-RPNA--TDNEVYEAAKAAHVDDFVRTFPDGYSTILGERGVTVSGGQKQRIAIARALLKNPPILILDEATSALDAESERIVQEALDKLSKGRTSLVIAHRLSTIKNADVIAVIDKGVMAEIGTHAAL 658 HSP 2 Score: 84.3445 bits (207), Expect = 1.193e-16 Identity = 130/586 (22.18%), Postives = 249/586 (42.49%), Query Frame = 0
Query: 292 ALIVALFRVLLPFVSPQIIKLLIKHMDSNEPVWQGFFYTIVL--LFSSLLSTMAFHAYQQHLHIS------------AIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMM--GLIMSPLT--ILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKC---VKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFM----RRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHA----IEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSS---LLSSFL-----GEMEKLSGQVQ------VRGS-IAYVPQQAWIQNMTLRDNILFDQEFSSTNYT-KVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQ 832
A+ VA F + +P + I+ ++ ++ +E V + L + LS + F+A Q I+ A +R L ++ + + ++ + GE+ + +S D Q +F ++ GL S +++MY + ++ S G++V + + GS KK Q Q +A + E + I+ ++ +A E M R + + R + G NF + +S +L TI +G Y+ D L ++ + ++ + VK S RI E++ + I + H+ +E T ++ + +L +L IP A+VGT G GK++ LL F G +E ++ +RGS I Y+ Q+ + ++ +NI + + ++ N + + ++ + T +GE G+ +SGGQKQR+++ARA+ + I +LD+ SA+DA + I + LD K +T +++ H ++ + D I V+ G +AE G++ L G +S + Q
Sbjct: 110 AIAVAYFNIKIPLLLGDIVNVVSSYI--SETVLSEMRHDNFLREMKEPTLSMIKFYAAQSICTIAYIYSLACLGERMAASLRKDLFNSIICQDIAFFDE----HKTGEIVSRLSADVQEFKSSFKLVISQGLRSSAQASGCIVSMYMISPQMT--SAMGVIVPTVILGGTYIGSYLRVLSKKAQAQVAKAT----AVGEECISNIRTVRGFAMEDAEMELYSREVDKTRDFNEALGLGIGVFQGASNF-FLNSIVLGTI-TYGGYLMSDDN--LNPGQLMSFLVSVQTIQRSITQVSLLFGHLVKGMASGSRIFEYIEKVPLIP---ISGGVKIPYHSFFGDVEFKNITFSYPTRPE-QAVLKDFSLRIPPSKTVALVGTSGGGKTTIAALLERFYDINGGGSLEIDGINIRDLDPSWLRGSAIGYINQEPVLFATSVIENIRYGRPNATDNEVYEAAKAAHVDDFVRTFPDGYSTILGERGVTVSGGQKQRIAIARALLKNPPILILDEATSALDAE-SERIVQEALDKLS---KGRTSLVIAHRLSTIKNADVIAVIDKGVMAEIGTHAALKRKGGIYSRLIEQ 671
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|3219824|sp|Q63120.1|MRP2_RAT (RecName: Full=Canalicular multispecific organic anion transporter 1; AltName: Full=ATP-binding cassette sub-family C member 2; AltName: Full=Canalicular multidrug resistance protein; AltName: Full=Multidrug resistance-associated protein 2) HSP 1 Score: 1063.14 bits (2748), Expect = 0.000e+0 Identity = 612/1557 (39.31%), Postives = 908/1557 (58.32%), Query Frame = 0
Query: 8 FCRDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPC-ILFLIASLIWSIYQTWTRGRASTVSSKYGPLFLAKFTFTLVILV----NLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFVGLALLQTAVDK-FLGAHISPPLFLFWLALLICEIPKLKIDIQSRM--VASGTVEEWVLLITYVPIILGLFIAHCWVDIDPRAAEDLSLEDKASCLSLLVFSWLDGLLWQGHKTPLKWKN---LPKSPRSMNVTDNV------------KAFTKQWRK-----------------QAEDKLV--------DFTSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHM-DSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYT--SNPV-------TSEVETDELKVLATTTKEPP-------------------------------KREVRVPSEEVESPEETDNLIEETADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETG--SDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
FC F+DL L+ + + ++ C T+LV +P L+L+A W +Y + R+ T S +LAK F + +L+ +L +G VP + P L + L +L + + S L LFW+ ++C + + + I++ + S ++ ++Y I+ L + D ++ AS LS + FSW D + +G+K PL ++ + + ++ +VT +AF ++ +K Q++D LV + T+ P L LFK L + I+ L LL F++PQ++KLLI + SN VW G+ I++ +L+ + +Y QH + + +R +++ ++Y+K+L LSN AR+ Y++GE N MSVD+Q++++ YM + S + I ++++FL+ EL + LAG+ V + IP+N + ++ +QVQ ++ KD RLK+MNE+L GIK+LK +AWE F ++ IR E+K + G+L + + F +PILV++ F +YV +D +VL A+K F +I LFN++R PL P ++ VS+ R+ +L ++D++ + +N A++ +EA+ TWD D ++ + +NL I G L A+VGTVG+GKSSL+S+ LGEME + G + ++GS AYVPQQ+WIQN T++DNILF E++ Y +V++ C L PDL IL D EIGE GINLSGGQKQRVSLARA Y DADIY+LDDPLSAVDAHVGK IF +V+ G L KTR+ VTH ++FL ++D I+VL G + E GSY+ LL F+ + S P SE E D+ ++ T + P K +++ + V +E E LI++E G+V +Y Y+Q++G ++ YGL +V +N WLS W ++ T S +GV+G +G+ Q I L I +C ASK +H +LL ++R+PM FFDT PTGRIVNRFS DI VD ++P L + C F +V++C +TP+FA +IIPL ++Y VQ F+V S+Q++R +SVTKS I++HFSET+TGL IRA++ Q RFL ++ ++ C F +++NRWL +R+E++GNLVVF +A+ V+ R+ L+ + G ++ AL I TLNW++RM E ETN VA+ERI EY + E+EA W D + WP G + F +Y RYR LDLVLKGI ++S EK+G+ GRTGAGKSSLT LFRI+E+ G+I+IDG D+A +GLH LR R+TIIPQDP+LF+G+LR NLDP +SD E+W AL+ AHL+ +S L+LGL E++EGG+N S+GQRQL+CL RA+LRK+KILVLDEATAAVDL TD LIQ+TIR+EF CTVITIAHRL+TI+D D+I V +G+I E+GSP ELL+N S M +AG+
Sbjct: 4 FCNSTFWDLSLL-ESPEADLPLCFEQTVLVWIPLGFLWLLAP--WQLYSVY---RSRTKRSSITKFYLAKQVFVVFLLILAAIDLSLALTEDTGQAT-----VPPVRYTNPILYLCTWLLVLAVQHSRQWCVRKNSWFLSLFWILSVLCGVFQFQTLIRALLKDSKSNMAYSYLFFVSYGFQIVLLILTAFSGPSDSTQTPSVT----ASFLSSITFSWYDRTVLKGYKHPLTLEDVWDIDEGFKTRSVTSKFEAAMTKDLQKARQAFQRRLQKSQRKPEATLHGLNKKQSQSQDVLVLEEAKKKSEKTTKDYPKSWLIKSLFKTFHVVILKSFILKLIHDLLVFLNPQLLKLLIGFVKSSNSYVWFGYICAILMFAVTLIQSFCLQSYFQHCFVLGMCVRTTVMSSIYKKALTLSNLARKQYTIGETVNLMSVDSQKLMDATNYMQLVWSSVIQITLSIFFLWRELGPSILAGVGVMVLLIPVNGVLATKIRNIQVQNMKNKDKRLKIMNEILSGIKILKYFAWEPSFQEQVQGIRKKELKNLLRFGQLQSLLIFILQITPILVSVVTFSVYVLVDSANVLNAEKAFTSITLFNILRFPLSMLPMVTSSILQASVSVDRLERYLGGDDLDTSAIRRVSN--FDKAVKFSEASFTWDPD--LEATIQDVNLDIKPGQLVAVVGTVGSGKSSLVSAMLGEMENVHGHITIQGSTAYVPQQSWIQNGTIKDNILFGSEYNEKKYQQVLKACALLPDLEILPGGDMAEIGEKGINLSGGQKQRVSLARAAYQDADIYILDDPLSAVDAHVGKHIFNKVV-GPNGLLAGKTRIFVTHGIHFLPQVDEIVVLGKGTILEKGSYRDLLDKKGVFARNWKTFMKHSGPEGEATVNNDSEAEDDDDGLIPTMEEIPEDAASLAMRRENSLRRTLSRSSRSSSRRGKSLKNSLKIKNVNVLKEKEK----EVEGQKLIKKEFVETGKVKFSIYLKYLQAVGWWSILFIILFYGLNNVAFIGSNLWLSAWTSDSDNLNGTNNSSSHRDMRIGVFGALGLAQGICLLISTLWSIYACRNASKALHGQLLTNILRAPMRFFDTTPTGRIVNRFSGDISTVDDLLPQTLRSWMMCFFGIAGTLVMICMATPVFAIIIIPLSILYISVQVFYVATSRQLRRLDSVTKSPIYSHFSETVTGLPIIRAFEHQQRFLAWNEKQIDINQKCVFSWITSNRWLAIRLELVGNLVVFCSALLLVIYRKTLTGDVVGFVLSNALNITQTLNWLVRMTSEAETNIVAVERISEYINVENEAPW--VTDKRPPADWPRHGEIQFNNYQVRYRPELDLVLKGITCNIKSGEKVGVVGRTGAGKSSLTNCLFRILESAGGQIIIDGIDVASIGLHDLRERLTIIPQDPILFSGSLRMNLDPFNKYSDEEVWRALELAHLRSFVSGLQLGLLSEVTEGGDNLSIGQRQLLCLGRAVLRKSKILVLDEATAAVDLETDSLIQTTIRKEFSQCTVITIAHRLHTIMDSDKIMVLDNGKIVEYGSPEELLSNRGS-FYLMAKEAGI 1533
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|308153583|sp|Q92887.3|MRP2_HUMAN (RecName: Full=Canalicular multispecific organic anion transporter 1; AltName: Full=ATP-binding cassette sub-family C member 2; AltName: Full=Canalicular multidrug resistance protein; AltName: Full=Multidrug resistance-associated protein 2) HSP 1 Score: 1047.73 bits (2708), Expect = 0.000e+0 Identity = 605/1557 (38.86%), Postives = 900/1557 (57.80%), Query Frame = 0
Query: 8 FCRDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPC-ILFLIASLIWSIYQTWTRGRASTVSSKYGPLFLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFVG---LALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVA--SGTVEEWVLLITY-VPIILGLFIAHCWVDIDPRAAEDLSLEDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRK---------------------------------QAEDKLV--DFTSPIR--------PFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHM-DSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYT--SNPVT-------SEVETDELKVLATTTKEPP-------KRE----------------------VRVPSEEVESPEETDNLIEETADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETG--SDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
FC F++ + ++ + ++ C T+LV +P L+L+A W + + ++ T S L+LAK F +L+ + G VP+ + P L ++G L LL ++ S L LFW+ ++C + + I++ + S + I+Y I++ +F A + + AS LS + +SW D ++ +G+K PL +++ + M V F ++ Q++D LV D + P L LFK L + ++ L + FVSPQ++KLLI D + +W G+ I+L ++L+ + Y Q +++R +++ ++Y+K+L LSN AR+ Y+VGE N MSVDAQ++++ +M L S L I+++++FL+ EL + LAG+ V + IPIN S K +QV+ ++ KD RLK+MNE+L GIK+LK +AWE F ++ +R E+K + +L + F + +P+LV++ F +YV +D ++L A K F +I LFN++R PL P + ++ VS +R+ ++L ++D++ + H N A++ +EA+ TW+ D + + +NL I G L A++G VG+GKSSL+S+ LGEME + G + ++G+ AYVPQQ+WIQN T++DNILF EF+ Y +V+ C L PDL +L D EIGE GINLSGGQKQR+SLARA Y + DIYLLDDPLSAVDAHVGK IF +VL G LK KTR+LVTH+++FL ++D I+VL NG + E GSY LLA F++ L + + P SE E D+ ++++ + P +RE + + V S +E + L++ LI++E G+V +Y Y+Q+IG F ++ + + SV +N WLS W ++ T + + +GVYG +G+ Q I F AS ++H +LL ++R+PM FFDT PTGRIVNRF+ DI VD +P L I C +S +V++C +TP+F ++IPLG+IY VQ F+V S+Q++R +SVT+S I++HFSET++GL IRA++ Q RFL ++ R+ C F +++NRWL +R+E++GNL VFF+A+ V+ R+ LS G ++ AL I TLNW++RM E+ETN VA+ERI EYT E+EA W D + WP++G + F +Y RYR LDLVL+GI ++ S EKIG+ GRTGAGKSSLT LFRI+EA G+I+IDG DIA +GLH LR ++TIIPQDP+LF+G+LR NLDP +SD EIW AL+ AHLK ++ L+LGL HE++E G N S+GQRQL+CL RALLRK+KILVLDEATAAVDL TD+LIQ+TI+ EF HCTVITIAHRL+TI+D D++ V +G+I E GSP ELL P M +AG+
Sbjct: 5 FCNSTFWNSSFL-DSPEADLPLCFEQTVLVWIPLGYLWLLAP--WQLLHVY---KSRTKRSSTTKLYLAKQVFVGFLLILAAIELALVLTEDSG-QATVPAVRYTNPSL--YLGTWLLVLLIQYSRQWCVQKNSWFLSLFWILSILCGTFQFQTLIRTLLQGDNSNLAYSCLFFISYGFQILILIFSAFSENNESSNNPSSI-----ASFLSSITYSWYDSIILKGYKRPLTLEDVWEVDEEMKTKTLVSKFETHMKRELQKARRALQRRQEKSSQQNSGARLPGLNKNQSQSQDALVLEDVEKKKKKSGTKKDVPKSWLMKALFKTFYMVLLKSFLLKLVNDIFTFVSPQLLKLLISFASDRDTYLWIGYLCAILLFTAALIQSFCLQCYFQLCFKLGVKVRTAIMASVYKKALTLSNLARKEYTVGETVNLMSVDAQKLMDVTNFMHMLWSSVLQIVLSIFFLWRELGPSVLAGVGVMVLVIPINAILSTKSKTIQVKNMKNKDKRLKIMNEILSGIKILKYFAWEPSFRDQVQNLRKKELKNLLAFSQLQCVVIFVFQLTPVLVSVVTFSVYVLVDSNNILDAQKAFTSITLFNILRFPLSMLPMMISSMLQASVSTERLEKYLGGDDLDTSAIRHDCN--FDKAMQFSEASFTWEHDS--EATVRDVNLDIMAGQLVAVIGPVGSGKSSLISAMLGEMENVHGHITIKGTTAYVPQQSWIQNGTIKDNILFGTEFNEKRYQQVLEACALLPDLEMLPGGDLAEIGEKGINLSGGQKQRISLARATYQNLDIYLLDDPLSAVDAHVGKHIFNKVL-GPNGLLKGKTRLLVTHSMHFLPQVDEIVVLGNGTIVEKGSYSALLAKKGEFAKNLKTFLRHTGPEEEATVHDGSEEEDDDYGLISSVEEIPEDAASITMRRENSFRRTLSRSSRSNGRHLKSLRNSLKTRNVNSLKEDEELVK--GQKLIKKEFIETGKVKFSIYLEYLQAIGLFSIFFIILAFVMNSVAFIGSNLWLSAWTSDSKIFNSTDYPASQRDMRVGVYGALGLAQGIFVFIAHFWSAFGFVHASNILHKQLLNNILRAPMRFFDTTPTGRIVNRFAGDISTVDDTLPQSLRSWITCFLGIISTLVMICMATPVFTIIVIPLGIIYVSVQMFYVSTSRQLRRLDSVTRSPIYSHFSETVSGLPVIRAFEHQQRFLKHNEVRIDTNQKCVFSWITSNRWLAIRLELVGNLTVFFSALMMVIYRDTLSGDTVGFVLSNALNITQTLNWLVRMTSEIETNIVAVERITEYTKVENEAPW--VTDKRPPPDWPSKGKIQFNNYQVRYRPELDLVLRGITCDIGSMEKIGVVGRTGAGKSSLTNCLFRILEAAGGQIIIDGVDIASIGLHDLREKLTIIPQDPILFSGSLRMNLDPFNNYSDEEIWKALELAHLKSFVASLQLGLSHEVTEAGGNLSIGQRQLLCLGRALLRKSKILVLDEATAAVDLETDNLIQTTIQNEFAHCTVITIAHRLHTIMDSDKVMVLDNGKIIECGSPEELLQIP-GPFYFMAKEAGI 1537
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|8134577|sp|Q28689.1|MRP2_RABIT (RecName: Full=Canalicular multispecific organic anion transporter 1; AltName: Full=ATP-binding cassette sub-family C member 2; AltName: Full=Canalicular multidrug resistance protein; AltName: Full=Epithelial basolateral chloride conductance regulator; AltName: Full=Multidrug resistance-associated protein 2) HSP 1 Score: 1020.38 bits (2637), Expect = 0.000e+0 Identity = 592/1553 (38.12%), Postives = 902/1553 (58.08%), Query Frame = 0
Query: 8 FCRDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCI-LFLIASLIWSIYQTWTRGRASTVSSKYGPLFLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFVGLALL------QTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQS--RMVASGTVEEWVLLITYVPIILGLFIAHCWVDIDPRAAEDLSLEDKASCLSLLVFSWLDGLLWQGHKTPLK----W--------------------KNLPKSPRSMNV--------TDNVKAFTKQWRKQAEDKLV--------DFTSPIRPFVSLWPI--LFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHM-DSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETD----------ELKVLATTTKEPP--------KRE----------------------VRVPSEEVESPEETDNLIEETADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETG--SDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELL--ANPTSAL 1464
FC F++ L+ ++ + ++ C T+LV +P I L+L+A W ++ + R+ T S +LAK +L+ + + G +P+ + P L + L +L Q+ V K S L LFW+ ++C + + I++ R S + I+Y IL + I + + D ++++ S+ AS LS + FSW D ++ +G+K PL W K L K+ ++ ++ K + Q++D LV + + F W + +FK L + ++ L LL F++PQ++KLLI + D N W G+ + I+L +L+ ++ Y + + +++ +Y+K+L +SN A+R Y++GE N MSVDAQ++++ ++ + S L I++++YFL+ EL + LAG+ V + IP+N + + +Q + ++ KD RL++MNE+L G+K+LK +AWE F +++ +R E+K ++ + + + F +P+LV++ F +YV +D ++L A+K F +I LFN++R P+ P + ++ VS+ R+ ++L+ ++D++ + N A++ +EA+ TWD + ++P + +NL I G L A+VGTVG+GKSSL+S+ LGEME + G + ++G+ AYVPQQ+WIQN T++DNILF EF Y +V+ C L PDL IL D EIGE GINLSGGQKQR+SLARA Y ++DIY+LDDPLSAVDAHVGK IF +VL G L KTR+LVTH+++FL ++D I+V++NG + E GSY LLA F++ L + + SE E + L ++ +E P KRE + ++ ++P+E + + LI++E G+V +Y Y+Q+IG ++F Y L SV +N WLS W + + T + + +G++G +G+ Q + CA AS ++H +LL ++R+PM+FF+T P GRIVNRF+ DI VD +P L + C +S ++++C +TP+FA +IIPL +IY VQ F+V S+Q++R +SVT+S I++HF+ET++GL IRA++ Q RFL +++ + C +++NRWL R+E++GNLVVF +A+ V+ R+ LS + G ++ AL I TLNW++RM E ETN VA+ERI EY E+EA W P G WP +G + F +Y RYR LDLVLKGI+ +++S EKIG+ GRTGAGKSSLT LFRI+EA G I IDG DIA +GLH LR ++TIIPQDPVLF+G+LR NLDP +SD EIW AL+ AHLK ++ L+ GL E+SE +N S+GQRQL+CL RALLRK+KILVLDEATAAVDL TD LIQ+TIR EF HCTVITIAHRL+TI+D D+I V +G I E+GSP ELL A P S +
Sbjct: 5 FCNSTFWNSSLL-DSPEADLPLCFEQTVLVWIPLIFLWLLAP--WQLFHVY---RSRTKRSPITKFYLAKQVLVGCLLILAVIELILVLTENSG-QATIPAVRYTNPILYLVTWLLVLLIQHSRQSCVQKN-----SWFLSLFWILSILCGTFQFQTLIRTLLRDSNSNLAYSCLFFISYGFQIL-ILILSAFSEKD-NSSKNPSV--TASFLSKISFSWYDSVVLKGYKRPLTLEDVWDIDEEFKAKTIVSRFEVHMAKELKKARKAFQKRQQKKSQKNSRLQGLNKN-QSQSQDVLVLEETKKKNKKSGTTKDFPKSWLVKTIFKTFYMVLLKSFLLKLVYDLLTFLNPQLLKLLITFVSDPNSYAWLGYIFAILLFAVALIQSICLQTYFHMCFNLGMCVGTTVMATVYKKALTISNLAKRQYTIGETVNLMSVDAQKLMDVTNFIHLVWSSVLQIVLSIYFLWVELGPSVLAGVGVMVLLIPVNGILATKNRNIQFKNMKYKDKRLRIMNEILSGMKILKYFAWEPSFKDQVHNLRKKELKNLRTFAYMQSVVMFLLYLTPVLVSVTTFSVYVLVDSNNILDAEKAFTSITLFNILRFPMSMLPNVISAMLQASVSVDRLEKYLSGDDLDTSAIQRDPN--FDKAVQFSEASFTWDRN--LEPTIRNVNLDIMPGQLVAVVGTVGSGKSSLMSAMLGEMENVHGHITIKGTTAYVPQQSWIQNGTIKDNILFGAEFDERRYQRVLEACALLPDLEILPGGDLAEIGEKGINLSGGQKQRISLARASYQNSDIYILDDPLSAVDAHVGKHIFNKVL-GPNGLLNGKTRLLVTHSLHFLPQVDEIVVVENGTILEKGSYSSLLAKKGVFAKNLKMFVKH-TDSEGEVTVNDGSEEDDDDDSGLISSIEEFPEDSISLTLKRENSLHRTLSRSSRSSGRRLKSLKNSLKAQNGKTPKEEEVV---KGQKLIKKEFMETGKVKFSIYLKYLQAIGWCSIVGIIFAYVLNSVAFIGSNLWLSAWTSDSNTYNGTNYPASQRDLRIGIFGVLGLAQGLTVLVASFWSASGCAHASNILHKQLLNNILRAPMSFFNTTPIGRIVNRFAGDISTVDDTLPQSLRSWMMCFLAIISTLIMICMATPVFAVIIIPLAIIYVAVQVFYVATSRQLRRLDSVTRSPIYSHFTETVSGLPVIRAFEHQQRFLKQNEIGIDTNQKCVSSWITSNRWLAFRLELVGNLVVFSSALMMVIYRDTLSGDVVGFVLSNALNITQTLNWLVRMTSETETNIVAVERITEYIKVENEAPWVTDKRPPAG--WPHKGEIQFSNYQVRYRPELDLVLKGINCDIKSMEKIGVVGRTGAGKSSLTNCLFRILEAAGGHITIDGIDIASIGLHDLRGKLTIIPQDPVLFSGSLRMNLDPFNNYSDEEIWRALELAHLKSFVAGLQHGLSREVSEAEDNLSIGQRQLLCLGRALLRKSKILVLDEATAAVDLETDHLIQTTIRNEFSHCTVITIAHRLHTIMDSDKIMVLDNGNIVEYGSPEELLESAGPFSLM 1529 HSP 2 Score: 77.7962 bits (190), Expect = 5.963e-13 Identity = 68/273 (24.91%), Postives = 116/273 (42.49%), Query Frame = 0
Query: 1199 SVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTI---RREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMK 1468
SV+++R+ +Y + + DP + AV F + + L+ ++ +++++ + + + G G+GKSSL ++ +E V G I I G +PQ + G ++ N+ + L+ L + L G EI E G N S GQ+Q I LARA + + I +LD+ +AVD I + + T + + H L+ + D I V +G I E GS + LLA K +K
Sbjct: 605 SVSVDRLEKYLSGDDLDTSAIQRDPNF------DKAVQFSEASFTWDRNLEPTIRNVNLDIMPGQLVAVVGTVGSGKSSLMSAMLGEMENVHGHITIKGTT-------------AYVPQQSWIQNGTIKDNILFGAEFDERRYQRVLEACALLPDLEILPGGDLAEIGEKGINLSGGQKQRISLARASYQNSDIYILDDPLSAVDAHVGKHIFNKVLGPNGLLNGKTRLLVTHSLHFLPQVDEIVVVENGTILEKGSYSSLLAKKGVFAKNLK 858
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|338817955|sp|Q8VI47.2|MRP2_MOUSE (RecName: Full=Canalicular multispecific organic anion transporter 1; AltName: Full=ATP-binding cassette sub-family C member 2) HSP 1 Score: 1013.06 bits (2618), Expect = 0.000e+0 Identity = 610/1560 (39.10%), Postives = 907/1560 (58.14%), Query Frame = 0
Query: 8 FCRDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPC-ILFLIASLIWSIYQTWTRGRASTVSSKYGPLFLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFH---YPC--LLVFVGLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVEEW--VLLITYVPIILGLFIAHCWVDIDPRAAEDLSLEDKASCLSLLVFSWLDGLLWQGHKTPL------------KWKNLPKSPRSMNVTDNVKA---------------------FTKQWRKQAEDKLV--------DFTSPIRPFVSLWPI--LFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHM-DSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSE---FLIQYTSNPVTSEVETDELKV-----LATTTKEPP--------KRE----------------------VRVPSEEVESPEETDNLIEETADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRT----GFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
FC F++L L+ + + ++ C T+LV +P L+L+A W +Y+ + R+ T +LAK F + +L+ G + P + + Y C LLV V Q + K S L +FW+ L+C I + + I++ + S + + + ++Y I+ L ++ D A + AS LS + FSW D + +G+K PL K K+L +++ D KA TK+ + Q++D LV + + F W + LFK L + I+ L +L F++PQ++K LI + D + W G+ Y I++ +L+ + Y Q + + +R +++ ++Y+K+L LSN ARR Y++GE N MSVD+Q++++ Y+ L S L I ++++FL+ EL + LAG+ + + +P+N + ++K+QVQ ++ KD RLK+MNE+L GIK+LK +AWE F ++ IR E++ + +L + F +P LV++ F +YV +D +VL A+K F +I LFN++R PL P + ++ VS+ R+ ++L + ++D + + H + A++ +EA+ TWD D ++ + +NL I G L A+VGTVG+GKSSL+S+ LGEME + G + ++GSIAYVPQQAWIQN T++DNILF E+ Y +VI C L PDL +L D EIGE GINLSGGQK RVSLARA Y DADIY+LDDPLSAVD HVGK IF +V+ G L KTR+LVTH ++FL ++D I+VL G + E GSY L+ F++ ++++ + V+ D + L T +E P +RE + + V + + + +++ LI++E G+V +Y Y+Q++G +V Y L V N WLS W +E + G+D + +GV+G +G+ Q I S L I +C ASK +H +LL ++R+PM+FFDT PTGRIVNRF+ DI VD +P L + C F +S +V++C +TPIF +IIPL ++Y VQ F+V S+Q++R +SVTKS I++HFSET++GL IRA++ Q RFL S+ ++ C F +++NRWL +R+E++GNL+VF +A+ V+ + +L+ G ++ AL I TLNW++RM E+ETN VA+ERI EY + ++EA W D K WP +G + F +Y RYR LDLVLKGI ++S EK+G+ GRTGAGKSSLT LFRI+E+ G+I+IDG DIA +GLH LR R+TIIPQDP+LF+GNLR NLDP +SD EIW AL+ AHLK ++ L+LGL HE++EGG+N S+GQRQL+CL RA+LRK+KILVLDEATAAVDL TD LIQ+TIR EF CTVITIAHRL+TI+D D+I V G+I E+GSP ELL+N M +AG+
Sbjct: 4 FCNSTFWNLSLL-KSPEADLPLCFEQTVLVWIPLGFLWLLAP--WQLYRIY---RSRTKRFAITKFYLAKQVFVVCLLILAAIDLSLALTEDTGQATIPPVKYTNPILYLCTWLLVLVIQHCRQCCIQKN-----SWFLSMFWILSLLCGIFQFQTLIRALLQDSKSNMTYSCLFFVSYGFQIVILILSAFSESSDSTHAPSAT----ASFLSSVTFSWYDSTVLKGYKHPLTIEDVWDIEENLKAKSLTSKFKTIMTKDLQKARQALQRRLKKSQQSPEGTSHGLTKK-QSQSQDVLVLEDSKKKKKKSEATKDFPKSWLVKALFKTFYVVILKSFILKLAHDILLFLNPQLLKFLIGFVKDPDSYPWVGYIYAILMFSVTLIQSFFLQCYFQFCFVLGMTVRTTIIASVYKKALTLSNLARRQYTIGETVNLMSVDSQKLMDVTNYIHLLWSSVLQIALSIFFLWRELGPSILAGVGLMVLLVPVNGVLATKIRKIQVQNMKNKDKRLKIMNEILSGIKILKYFAWEPSFKEQVNSIRKKELRNLLRFSQLQTILIFILHLTPTLVSVITFSVYVLVDSQNVLNAEKAFTSITLFNILRFPLAMLPMVISSVIQASVSVDRLEQYLGSDDLDLSAIRHVCH--FDKAVQFSEASFTWDRD--LEATIQDVNLDIKPGQLVAVVGTVGSGKSSLISAMLGEMENVHGHITIKGSIAYVPQQAWIQNGTIKDNILFGSEYDEKKYQRVIEACALLPDLEMLPGGDMAEIGEKGINLSGGQKHRVSLARATYQDADIYILDDPLSAVDTHVGKHIFNKVV-GPNGLLSGKTRILVTHGIHFLPQVDEIVVLGKGTILEKGSYSDLMDKKGVFAKNWKTFMKHSGPEGEATVDNDSEEEDGDCGLIPTVEEIPDDAASLTMRRENSLRRTLSRSSRSGSRRGKSLKSSLKIKSVNALNKKEEVVK--GQKLIKKEFVETGKVKFSIYLKYLQAVGWWSLLFIVIFYVLNYVAFIGTNLWLSAWTSDSEK--QNGTDNSPSQRDMRIGVFGALGIAQGIFLLSSSLWSIYACRNASKTLHRQLLTNILRAPMSFFDTTPTGRIVNRFAGDISTVDDTLPQTLRSWLLCFFGIVSTLVMICMATPIFIIIIIPLSILYVSVQVFYVATSRQLRRLDSVTKSPIYSHFSETVSGLPVIRAFEHQQRFLANSEKQIDTNQKCVFSWITSNRWLAIRLELVGNLIVFCSALLLVIYKNSLTGDTVGFVLSNALNITQTLNWLVRMTSEVETNIVAVERINEYINVDNEAPW--VTDKKPPADWPKKGEIQFNNYQVRYRPELDLVLKGITCNIKSTEKVGVVGRTGAGKSSLTNCLFRILESAGGQIIIDGIDIASIGLHDLRGRLTIIPQDPILFSGNLRMNLDPFNKYSDEEIWRALELAHLKSFVAGLQLGLLHEVTEGGDNLSIGQRQLLCLGRAVLRKSKILVLDEATAAVDLETDSLIQTTIRNEFSQCTVITIAHRLHTIMDSDKIMVLDSGKIVEYGSPEELLSN-MGPFYLMAKEAGI 1535
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|1723255|sp|Q10185.1|ABC2_SCHPO (RecName: Full=ATP-binding cassette transporter abc2; Short=ABC transporter abc2; AltName: Full=ATP-energized glutathione S-conjugate pump abc2; AltName: Full=Glutathione S-conjugate-transporting ATPase abc2) HSP 1 Score: 857.44 bits (2214), Expect = 0.000e+0 Identity = 496/1321 (37.55%), Postives = 759/1321 (57.46%), Query Frame = 0
Query: 191 WVDIDPRAAEDLSLEDK----ASCLSLLVFSWLDGLLWQGHKTPL----KWKNLPKSPRSMNVTDNVKAFTKQWRKQAEDKLVDFTSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHMDSN-----EPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLT-EIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAM-DPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAI--EMTEATLTWDS--DDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLA--DGKAF---SEFLIQYTSNPVTSEVETDELKVLATTTKEPPKREVRVPSEEVESPEETDNLIEETADDLIEE----------EKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSD-RTGFYLGVYGGIGVVQLILDFSRELLHIMSCA-QASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLS--RENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
W D E+ L A+ S + F WL L+ G++ L W +LP + RS N+T F K W A+ K + + +W +LF NH ++ +++ L + ++ F+ P +I+ ++ + S +P GF I + ++++ T Y Q + ++ R+ L+ A+Y+KSLRLS+ AR+ SVG++ NYMSVD Q++ + ++ ++ P I++A+ L+ + +L+G V + P N+ + K+ Q +Q++ KD R + M E++ I+ +KLYAWE F++++ ++R T E++++K G + NF++ +PILV+ FG ++ + T VL+ D +F ++LFNL++ PL P + ++ V++ RI FL A E+DS V + P + E+ + T +W + +P L ++ G L IVG VG GKSSLL + LG M+K SG V GSIAY QQ WI N T+++NILF E Y K IR C L D IL D+TE+GE GI+LSGGQK R+SLARAVYS +DIYLLDD LSAVD HV + + +L S +G L+ + +L T+++ L + I +L+NGK+ ESGS+ +L + D + F SEF + T++ ++ + + T++ + R P+ T L +E EK G+V KVYWTY ++ F ++ N WL W+ E + + G + + FYLG+Y G++ L L + CA ++ + +HD +++ V+R+PM+FF+T PTGRI+NRFSSD+ VD+V+ F + V+ V+C S+P+F +I+PL +Y + Q ++ S+++KR +SVT+S ++AHF E++ GL++IRAY +D F+ E+ RV FL S+NRW +RVE +G LVVF +A F VLS R N + G+ GLS++YA+ I +L +++R ++ETN V++ER+LEY SEA +P D + WP+ GA+ F Y+ RYR L LVL I + ++ EKIGI GRTGAGKS+LTL+LFR+IE G I +D +I +GLH LRSR+ IIPQ+ F G +R NLDPN +D EIW AL+ A LK I L GLY ++EGG N S GQRQL+CL RALL T++L+LDEATAAVD+ TD ++Q TIR F T++TIAHR+NT++D +RI V HG++ EF S +LL N S ++ ++GL
Sbjct: 174 WYPDDAAELEETGLRPSRFTYANIFSRISFGWLSPLMKFGYRNYLTESDAW-SLPPAERSSNLT---IVFEKNWISHAKKK--------KSSLYMWGVLFLNHWKLTVVIIVLKLVQDVVAFIQPNLIRKIVIFVSSYSSEHPQPPQVGFSLAIAMFLTNVVQTALLQQYFQLGMVLGMRWRSELITAIYRKSLRLSSAARQSRSVGDIVNYMSVDTQKVCDLTMFLFVIVSGPFQIVLALTNLYHLVGYGALSGAFVTFLLFPCNVVIASIFKRFQNRQMKNKDARSQFMTEIINNIRSIKLYAWENIFLQKLLQLRNTRELRMLKKIGIVNTIGNFTWLFAPILVSAATFGTFIVLYGKTRVLSVDIVFACLSLFNLLQFPLTMLPIVVSSVLEASVAISRIYGFLTAGELDSNAVQRYPANKEPSGVCLEIKKGTFSWSGPGQNAAEPTLRDIDFVARRGELCCIVGKVGMGKSSLLEACLGNMQKHSGSVFRCGSIAYAAQQPWILNATIQENILFGLELDPEFYEKTIRACCLLRDFEILADGDQTEVGEKGISLSGGQKARISLARAVYSRSDIYLLDDILSAVDQHVNRDLVRNLLGS-KGLLRSRCVILSTNSLTVLKEASMIYMLRNGKIIESGSFTQLSSSPDSQLFQLLSEFSKKDTASSTGADTPLSRSQSVITSSTDVTSSASRSSDTVSNYPKATIKGTGRIRKRLTDEDNVKATGQAAEKMERGKVKWKVYWTYFKACSLFLIFLYFLFIIGGIGMNVGTNVWLKHWS---EVNTQLGYNPKPYFYLGIYTLFGLLSCALISLSSLTITVFCAIKSCRYLHDSMVKAVLRAPMSFFETTPTGRILNRFSSDVYRVDEVISRVFMFFFRNLFQIVFVLAVICYSSPMFMILIVPLFFLYRYNQVYYTQTSRELKRLDSVTRSPLYAHFQESLGGLSTIRAYDMEDTFISENDIRVDTNHRIWFLYFSSNRWQAIRVEAIGALVVFSSAFFGVLSAVRGNPNSGLVGLSLSYAVQITQSLTFVVRQSVDVETNIVSVERMLEYIGLPSEAPSIIP-DHRPPEGWPSHGAIKFDHYSVRYRENLPLVLNDISVNIKPQEKIGIVGRTGAGKSTLTLALFRLIEPTSGDIQLDDINITSIGLHDLRSRLAIIPQENQAFEGTIRENLDPNANATDEEIWHALEAASLKQFIQTLDGGLYSRVTEGGANLSSGQRQLMCLTRALLTPTRVLLLDEATAAVDVETDAIVQRTIRERFNDRTILTIAHRINTVMDSNRILVLDHGKVVEFDSTKKLLENKASLFYSLAKESGL 1477
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|31340495|sp|Q9P5N0.1|ABC3_SCHPO (RecName: Full=ATP-binding cassette transporter abc3) HSP 1 Score: 854.358 bits (2206), Expect = 0.000e+0 Identity = 512/1463 (35.00%), Postives = 808/1463 (55.23%), Query Frame = 0
Query: 67 SKYGPLFLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFVGLALLQTAVDKFLGAHISPPLFLFWLALLICEI------PKLKIDIQSRMVASGTVEEWVLLITYVPIILGLFIAHC---WVDIDPRAAEDLSLEDK----ASCLSLLVFSWLDGLLWQGHKTPLKWKN---LPKSPRSMNVTDNVKAFTKQWRKQAEDKLVDFTSPIRPFVSLWPILFKNHGWRALIALIV--ALFRVLLPFVSPQIIK---LLIKHMDSNEPVW--QGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLT-EIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMD-PTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAI--EMTEATLTWDSD---DGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLA-----------------DGKAFSEFLIQYTSNPVT--SEVETDELKVLATTTKEPP----KREVRVPSEEVESPEETDNLIEETADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCA-QASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLS--RENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
S++ +++ F+ LVI+ + +VG K + F ++ + + LQ A L ++ L +FWL ++ + P + I +R++ T L + V I +++ C W D E+ + A+ S L FSW+ + G+ LK + LP RS N+ + F W +++K R + LW +LF NH W+ L+ALI L + +L FV P +I+ L I S P +GF I++L ++ L T+ Y Q + + ++ + LL ++Y+KSL LS+ AR+ S+G++ NYM+VD Q+I + Y+ ++ P I +A+ L+ + ++ G+ I P N+ + KK Q ++ KD+R KLM E++ I+ +KLYAWE PF++++ IR T E+ ++K G + A +F++ + I+VT FG ++ T LTAD +F A++LFNL++ PL P + ++ VS+ RI EFL A E+D V PH I E+ T +W V P L Q+N G LT I G VGAGKSSLL + +G M K SG V GS+AY QQ WI + T+R+NILF EF Y K I C L+ D I D+TE+G+ G +LSGGQK R+SLARA+YS ADIYLLDD LS+VD HV + + + EG L+ VL T+++N L + D+I +L NGK+ E G+Y+ L D + E Y S ++ + + L+ +++ ++ K R P + + ++ + +T D+L++ G+V VYW Y +S F +++ N WL W++ N + FYLG+Y G + S L + C ++ + +HD +L+ ++R+PM FF+T +GRI+NRFS+D+ VD+VV + L ++ V+C S P+ +I+PL +Y + + ++V S+++KR ++VT+S ++AH E+++GL++IRAY Q+ F+ E+ R+ F+ S++RW +RVE +G+L++F A + +LS + + +PG+ G S++YA+ I L+++++ + E N+V++ERILEY + +SEA +P + + WPT+GAVSF Y+ +YR L L I++E+ EKIGI GRTGAGKS+L ++LFRIIE +G+I ID +DI + GL+ LRSR++IIPQ+ +F GN+R NLDPN +D +IW L+ A LK IS L+ GLY ++EGG NFS GQRQLICLAR LL T+IL+LDEATA+V TD ++Q TIR+ F+ T++T+AHR+NT++D DRI V HG++ EF + +LL N S ++ ++GL
Sbjct: 41 SQFWTIWMKFFSIALVIITQI---------YVGYKTKNIGWNFF---SVVTYCFVLFLQFAEQSTLRVPMAS-LLIFWLLKVVTSLLILLFSPYIAITSMARLLTLIT-----LFCSLVCFISEVYVPPCNRVWYSDDTNEVEEKGIRPSEVRYANIFSKLSFSWISSFIKFGYTNYLKESDVWLLPPDERSGNL---IIGFEDWWIYHSKNK--------RRSLFLWKLLFFNH-WK-LVALITITKLIQDVLAFVQPTLIQKTILFISSYTSPNPESPSRGFIIAILVLVANFLQTLLLQQYNQLIMLLGMRWKTELLASIYRKSLLLSSSARQNRSIGDIINYMAVDTQKISDLPIYLFIIVSGPFQIALALSNLYHLMGYSAFTGVAASVILFPCNIIVANVYKKFQSILMKNKDSRSKLMTEIINNIRSIKLYAWETPFLQKLLHIRNTKELSMLKKIGFITAIGDFAWIFTTIIVTTVAFGAFIIFHGKTQALTADIVFPAVSLFNLLQFPLAMLPTVISSLLEASVSVSRIYEFLIAQELDYNGVQRFPATEIPHEICLEIKSGTFSWSKKTLKQQVTPTLRQINFVAKNGELTCIFGKVGAGKSSLLEACMGNMYKNSGSVFQCGSLAYAAQQPWIFDATIRENILFGSEFDPELYEKTIHACCLKRDFEIFTEGDQTEVGQKGASLSGGQKSRISLARAIYSQADIYLLDDVLSSVDQHVSRDLIKNLF-GPEGFLRTHCVVLTTNSLNVLKEADSIYILSNGKIVEKGNYEHLFVSTNSELKQQLSEFNDEKDTQPLPEHTTSYPSTQISLAPSIHVEGLETYSSSERKDSSNKYKSRKRNPIRQKVTEDDKGKCVAQT-DELVQR-----GKVKWHVYWMYFKSCSIGLILLYFFFIISGIMMNVATNVWLKHWSEENGKSSSELNPSPYFYLGIYLFFGFLSCAFISSSSLTMTVLCGIRSGRYLHDSMLKTILRAPMGFFETTSSGRILNRFSNDVYKVDEVVSLTFMFFFRNSIQVLFILGVICYSAPLSLLLIVPLFFLYLYNRAYYVRTSRELKRLDNVTRSPLYAHVQESLSGLSTIRAYGMQETFVEENDLRIDTNHRVWFMFFSSSRWQAIRVECIGDLIIFCTAFYGILSAIKGSPNPGLVGFSLSYAIQITQGLSFIVQQSVDAENNTVSVERILEYINVKSEAPEIIP-ENRPPCEWPTDGAVSFNHYSAKYREDLSFALNNINIEISPREKIGIVGRTGAGKSTLAMALFRIIEPTEGKIEIDNEDITKFGLYDLRSRLSIIPQESQIFEGNIRENLDPNHRLTDKKIWEVLEIASLKNCISQLEDGLYSRVAEGGANFSSGQRQLICLARVLLTSTRILLLDEATASVHAETDAIVQQTIRKRFKDRTILTVAHRINTVMDSDRILVLDHGKVVEFDATKKLLENKDSMFYSLAKESGL 1464
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|75017603|sp|Q8ST87.1|ABCCA_DICDI (RecName: Full=ABC transporter C family member 10; AltName: Full=ABC transporter ABCC.10) HSP 1 Score: 843.573 bits (2178), Expect = 0.000e+0 Identity = 473/1284 (36.84%), Postives = 726/1284 (56.54%), Query Frame = 0
Query: 203 SLEDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRKQAEDKLVDFTSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLI------KHMDSNEPVWQGFFYTIVLLFSSLLSTM-AFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDELKVLATTTKEPPKREVRVPSEEVESPEETDNLIEETADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPET---GSDRTGFY----LGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAG 1472
S E+ ++ LS L FSW DG + + L+ +L K K W + + +P S F+ G L+++ + V + FV P+I+ ++ K S E G++Y +++ ++++ + +HA + + ++R+ ++ +Y+K+++LSN AR S G++ N MS DAQR+VE F ++ I+I + L+ ++ + GL + IP N +K + + + + D+R+K NE+L IK++KLYAWE F +++ E R EIK++ R + + P I V Y + + L A +IF A++ NL+R PL P + +++ ++ KR+ +FL E+ I N P+ + M +T TW+ L +N SLT +VG+VG+GKS+L+ + LGE+E + G++ ++GSIAYVPQQAWI N TL++NI+F +E Y KV+ C L+ D+ + D EIGE GINLSGGQKQRVS+ARAVYSDAD+Y+LDDPLSAVD+HVGK +F + +G L KT +LV + +N+L DN +VLK+G++ E G+Y +L+ FS L +Y + + D + K E+ + +E P+ + T LI EE++ G V KVYW YV + G F + + L + +++WLS W + E+ G + TG LG+Y G+G+ + + + ++ AS+ IH +L +++ PM FFD P GRI+NRF+ D+DG+D ++ +S + ++ I++V P + P+ +I+FF+Q F+ S+ ++R E++T+S IF HFSET+ G+ SIRAY++Q + +Q R+ NC + NRWLGLR++ L NL+ FFA IF + ++ +SP GL++ YAL + LN+ + ET ++ERI +Y EA + D + WP G++ F + RYR GLD VLKGI E+++ EKIGI GRTGAGKSS+ L+LFR+IEA +G I IDG++IA+ GL LR + IIPQDPVLF+G LR NLDP S+ +++S ++ + + L+ GL +++E GENFSVGQRQLI LARALLRK KILVLDEATA+VD +D LIQ+TIR +F +CT++TIAHRLNTI+D DRI V G+I+EF P LL N L + ++ G
Sbjct: 29 SPEENSNFLSNLTFSWADGFVIHCFRNVLQLSHLWDLASYDKSEYLAKKIAKSWEIEIQ----------KPKPSYLRAGFRAFGKLQLLSIFLYAISVGIQFVGPEILGRMVTFVVESKLGTSTEDPNMGYYYALIMFGTAMIGSFCTYHANRISFR-TGDRLRSIIVLDVYKKAIKLSNSARSDTSPGQIVNLMSNDAQRMVEVFGMFNNGALALPQIIICLALLYKKIGWPTFVGLGLMLAAIPFNGMAAKKLTETRKYLVSLSDSRVKATNEILQAIKIIKLYAWEDSFAKKVIEHRNNEIKLLFSYSRYRTILIVIISALPTAAAILVISSYYGHEKS--LDASRIFSALSYLNLLRLPLGFLPIIIALGIQMQIAGKRVTDFLLLPEMKDIQQID--NPSLPNGVYMKNSTTTWNKLKEDSFGLKNINFEATGTSLTMVVGSVGSGKSTLVQAMLGELEIIDGEIGIKGSIAYVPQQAWIINATLKENIIFGKELDEERYQKVLEVCALKRDIELFPQGDSVEIGERGINLSGGQKQRVSIARAVYSDADVYILDDPLSAVDSHVGKHLFHKCF---KGILSSKTVILVANQLNYLPFADNTVVLKSGEIVERGTYYELINSKLEFSSILEKYGVDENVISKKDDIDEDEDEDQDTIEKVEIDLNKDEKSQPKSKSS---NTDGTLISEEESEQGAVAGKVYWKYVTAGGGLLFLVSMIFFLLETGSKTFSDWWLSHWQTESSERMESILLGEEPTGLTDDQNLGIYIGLGMAAVFISVCKNFIYYEYSVYASRAIHHELFNALLKKPMYFFDQTPIGRIINRFTRDLDGIDNLIATSISTFLTLMLTVIATIILVSIIVPFLLIPLAPISIIFFFLQYFYRYTSRGLQRIEAITRSPIFNHFSETLNGVVSIRAYKKQQENILINQKRLDDNNNCYLTLQAMNRWLGLRLDFLANLITFFACIFITIDKDTISPANVGLALGYALSLTGNLNYAALQAADTETKMNSVERISQYIRGAVEAPQIID-DCRPSPDWPINGSIKFDNLVMRYREGLDPVLKGITCEIKAKEKIGIVGRTGAGKSSIVLALFRLIEASEGSISIDGENIAKFGLKDLRRNLAIIPQDPVLFSGTLRENLDPFNERSEEDLFSTIEDIQMSAVVKSLEGGLDSKVTENGENFSVGQRQLIVLARALLRKPKILVLDEATASVDGQSDSLIQATIRNKFSNCTILTIAHRLNTIMDSDRIMVLDAGKISEFDEPWTLLQNQNGLLTWLVDETG 1290
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|269849624|sp|O95255.2|MRP6_HUMAN (RecName: Full=Multidrug resistance-associated protein 6; AltName: Full=ATP-binding cassette sub-family C member 6; AltName: Full=Anthracycline resistance-associated protein; AltName: Full=Multi-specific organic anion transporter E; Short=MOAT-E) HSP 1 Score: 838.565 bits (2165), Expect = 0.000e+0 Identity = 523/1501 (34.84%), Postives = 805/1501 (53.63%), Query Frame = 0
Query: 19 VWNTTDPN------VTQCMRDTLLVGVPCILFLIASLIWSIYQTWTRGRASTVSSKYGPLFLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFVGLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVEEWVLLITYV--PIILGLFIAHCWVDIDPRAAEDLSL-----EDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRK-----QAEDKLVDF------------TSPI--------RPFV-SLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHM-DSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDS--TNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDELKVLATTTKEP-----PKREVRVPSEEVESPEETDNLIEETADDLIEEEKTVAG-----------RVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYL--GVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLAN 1459
VWN T+P ++ C T V VP + + I+ ++ GR + PLF AK ++V + P L H L + A+ ++ G S LF +WL + S V L TY+ +++ F+ C D P ED E A+ S F W+ GL+W+G++ PL+ K+L R + + V K+W + + +K + F T P RP + ++W + L +I +FR F P+++ L ++ + D P W+G+ +++ S+ L T+ L + +++R+++ G +Y+K L LS+ +R+ +VG++ N +SVD QR+ E+ Y+ GL + + I++ +L+ L ++L + VF +P+N F SK Q +Q++ KD+R +L + +L K +K + WE F+ R+ IR E+ ++ G L++ S+ S LV + VF ++ + + + A+K FV + + N++ PF++ V+ VS R+ FL E+D + + + I + AT W + P L ++NL++P G L A+VG VGAGKSSLLS+ LGE+ K+ G V + G++AYVPQ+AW+QN ++ +N+ F QE +V+ C L+PD+ T IGE G+NLSGGQKQR+SLARAVY A +YLLDDPL+A+DAHVG+ +F QV+ G L+ TR+LVTH ++ L + D IIVL NG +AE GSYQ+LL A L Q E ET+ T+TK+P +R ++S E D E ++ ++ AG RV A V+ Y++++GT +FL+ V YWLS WAD P G +T L G++G +G +Q I F+ ++ A+AS+++ +LL V+RSP++FF+ P G ++NRFS + D VD +P L ++ AF L V +VV +TP+ I+PL L+Y Q +V+ S Q++R ES + S++ +H +ET G +RA++ Q F+ ++ ARV + +F + A+RWL VE+LGN +VF AA AVLS+ +LS G+ G S++ AL + TL W++R +LE + V++ER+ +Y EA W LP WP G + F+ + RYR L L ++G+ ++ + EK+GI GRTGAGKSSL L R+ EA +G I IDG IA +GLHTLRSRI+IIPQDP+LF G+LR NLD + HSD IW+AL+ LK ++ L L ++ ++ GE+ SVGQ+QL+CLARALLRKT+IL+LDEATAAVD T+ +Q+ + F CTV+ IAHRL +++DC R+ V GQ+AE GSPA+LLA
Sbjct: 13 VWNQTEPEPAATSLLSLCFLRTAGVWVPPMYLWVLGPIYLLF-IHHHGRGYL---RMSPLFKAKMVLGFALIVLCTSSVAVALWKIQQGTPEAPEFLIHPTVWLTTMSFAVFLIHTERKKGVQSSGVLFGYWLLCFVLPATNAAQQASGAGFQSDPVRH---LSTYLCLSLVVAQFVLSCLADQPPFFPEDPQQSNPCPETGAAFPSKATFWWVSGLVWRGYRRPLRPKDLWSLGRENSSEELVSRLEKEWMRNRSAARRHNKAIAFKRKGGSGMKAPETEPFLRQEGSQWRPLLKAIWQVFHSTFLLGTLSLIISDVFR----FTVPKLLSLFLEFIGDPKPPAWKGYLLAVLMFLSACLQTLFEQQNMYRLKVLQMRLRSAITGLVYRKVLALSSGSRKASAVGDVVNLVSVDVQRLTESVLYLNGLWLPLVWIVVCFVYLWQLLGPSALTAIAVFLSLLPLNFFISKKRNHHQEEQMRQKDSRARLTSSILRNSKTIKFHGWEGAFLDRVLGIRGQELGALRTSGLLFSVSLVSFQVSTFLVALVVFAVHT-LVAENAMNAEKAFVTLTVLNILNKAQAFLPFSIHSLVQARVSFDRLVTFLCLEEVDPGVVDSSSSGSAAGKDCITIHSATFAWSQES--PPCLHRINLTVPQGCLLAVVGPVGAGKSSLLSALLGELSKVEGFVSIEGAVAYVPQEAWVQNTSVVENVCFGQELDPPWLERVLEACALQPDVDSFPEGIHTSIGEQGMNLSGGQKQRLSLARAVYRKAAVYLLDDPLAALDAHVGQHVFNQVIGPG-GLLQGTTRILVTHALHILPQADWIIVLANGAIAEMGSYQELLQRKGALMCLLDQARQPGDRGEGETEP----GTSTKDPRGTSAGRRPELRRERSIKSVPEKDRTTSEAQTEVPLDDPDRAGWPAGKDSIQYGRVKATVHLAYLRAVGTPLCLYALFLFLCQQVASFCRGYWLSLWADD----PAVGGQQTQAALRGGIFGLLGCLQAIGLFASMAAVLLGGARASRLLFQRLLWDVVRSPISFFERTPIGHLLNRFSKETDTVDVDIPDKLRSLLMYAFGLLEVSLVVAVATPLATVAILPLFLLYAGFQSLYVVSSCQLRRLESASYSSVCSHMAETFQGSTVVRAFRTQAPFVAQNNARVDESQRISFPRLVADRWLAANVELLGNGLVFAAATCAVLSKAHLSAGLVGFSVSAALQVTQTLQWVVRNWTDLENSIVSVERMQDYAWTPKEAPWRLP-TCAAQPPWPQGGQIEFRDFGLRYRPELPLAVQGVSFKIHAGEKVGIVGRTGAGKSSLASGLLRLQEAAEGGIWIDGVPIAHVGLHTLRSRISIIPQDPILFPGSLRMNLDLLQEHSDEAIWAALETVQLKALVASLPGQLQYKCADRGEDLSVGQKQLLCLARALLRKTQILILDEATAAVDPGTELQMQAMLGSWFAQCTVLLIAHRLRSVMDCARVLVMDKGQVAESGSPAQLLAQ 1489 HSP 2 Score: 71.2478 bits (173), Expect = 5.830e-11 Identity = 64/213 (30.05%), Postives = 98/213 (46.01%), Query Frame = 0
Query: 627 MNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQV-------------RGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAF 826
++ I G IVG GAGKSSL S L E G + + R I+ +PQ + +LR N+ QE S + QL+ +A L + + + + G +LS GQKQ + LARA+ I +LD+ +AVD G + Q + + T +L+ H + + ++V+ G+VAESGS +LLA F
Sbjct: 1285 VSFKIHAGEKVGIVGRTGAGKSSLASGLLRLQEAAEGGIWIDGVPIAHVGLHTLRSRISIIPQDPILFPGSLRMNLDLLQEHSDEAIWAALETVQLKALVASLPGQLQYKCADRGEDLSVGQKQLLCLARALLRKTQILILDEATAAVDP--GTELQMQAMLGS--WFAQCTVLLIAHRLRSVMDCARVLVMDKGQVAESGSPAQLLAQKGLF 1493
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|6920083|sp|P39109.2|YCFI_YEAST (RecName: Full=Metal resistance protein YCF1; AltName: Full=Yeast cadmium factor 1) HSP 1 Score: 833.173 bits (2151), Expect = 0.000e+0 Identity = 486/1318 (36.87%), Postives = 752/1318 (57.06%), Query Frame = 0
Query: 206 DKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRKQAEDKLVDFTSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHM-DSNE--------------------PVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLT-EIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEI--DSTNVIHTANDLSPHAIEM-TEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKA-FSEFLIQY-TSNPVTSEVETDELKVLATTTKEPPKREVRV----------PSEEVESPEETDNLIE--ETADD--LIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSD-RTGFYLGVYGGIGVVQLILDFSRELLHIMSCA-QASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAV--LSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGH----TWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKL-GLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
D A+ S + FSW+ GL+ G++ L +L K PR+ + + + K W + + K P +S W I + G + L+A +L F PQ++++LIK + D N P+ +GF + T H Y ++ + + ++++L +YQKSL LSN+A L S G++ N MSVD Q++ + ++ + P I+I +Y L+ L + G+++ I +P+N F + KKLQ Q++ KD R ++++E+L IK LKLYAWE P+ ++ E+R E+K + G A +F + P LV+ F ++V + LT D +F A+ LFNL+ PL+ P L ++ VS+ R+ F E+ DS + ++ AI + +AT W L +N G+LT IVG VG+GK++LLS LG++ ++ G V GS+AYV Q WI N T+++NILF + + Y K I+ C L DLAIL D+T +GE GI+LSGGQK R+SLARAVY+ AD YLLDDPL+AVD HV + + VL G L KT+VL T+ V+ L D+I +L NG++ + G+Y ++ D + + L Y N S D + + P + E+ S+ + +D + + DD + + E G+V +Y Y ++ + ++ + + N WL W++ N + GS+ YL +Y +G+ + + ++ + C ASK +H+ + V+R+PM FF+T P GRI+NRFS+DI VD ++ S A I V+C++T F +IIPL + Y + Q++++ S++++R +S+T+S I++HF ET+ GLA++R Y QQ RF H +Q R+ + + +++ANRWL R+E++G++++ AA +V L + L+ G+ GLS++YAL I TLNW++RM E+ETN V++ERI EY +SEA PL + GH WP++G + F +Y+TRYR LDLVLK I++ ++ NEK+GI GRTGAGKSSLTL+LFR+IEA +G I+ID I ++GL+ LR +++IIPQD +F G +R N+DP ++D IW AL+ +HLK H+ + GL +++EGG N SVGQRQL+CLARA+L +KILVLDEATAAVD+ TD ++Q TIR F+ T++TIAHRLNTI+D DRI V +G++AEF SP +LL++ S ++ +AGL
Sbjct: 213 DSANIFSRITFSWMSGLMKTGYEKYLVEADLYKLPRNFSSEELSQKLEKNWENELKQK-------SNPSLS-WAIC-RTFGSKMLLAAFFKAIHDVLAFTQPQLLRILIKFVTDYNSERQDDHSSLQGFENNHPQKLPIVRGFLIAFAMFLVGFTQTSVLHQYFLNVFNTGMYIKSALTALIYQKSLVLSNEASGLSSTGDIVNLMSVDVQKLQDLTQWLNLIWSGPFQIIICLYSLYKLLGNSMWVGVIILVIMMPLNSFLMRIQKKLQKSQMKYKDERTRVISEILNNIKSLKLYAWEKPYREKLEEVRNNKELKNLTKLGCYMAVTSFQFNIVPFLVSCCTFAVFVYTED-RALTTDLVFPALTLFNLLSFPLMIIPMVLNSFIEASVSIGRLFTFFTNEELQPDSVQRLPKVKNIGDVAINIGDDATFLWQRKPEYKVALKNINFQAKKGNLTCIVGKVGSGKTALLSCMLGDLFRVKGFATVHGSVAYVSQVPWIMNGTVKENILFGHRYDAEFYEKTIKACALTIDLAILMDGDKTLVGEKGISLSGGQKARLSLARAVYARADTYLLDDPLAAVDEHVARHLIEHVL-GPNGLLHTKTKVLATNKVSALSIADSIALLDNGEITQQGTYDEITKDADSPLWKLLNNYGKKNNGKSNEFGDSSESSVRESSIPVEGELEQLQKLNDLDFGNSDAISLRRASDATLGSIDFGDDENIAKREHREQGKVKWNIYLEYAKACNPKSVCVFILFIVISMFLSVMGNVWLKHWSEVNSRY---GSNPNAARYLAIYFALGIGSALATLIQTIVLWVFCTIHASKYLHNLMTNSVLRAPMTFFETTPIGRILNRFSNDIYKVDALLGRTFSQFFVNAVKVTFTITVICATTWQFIFIIIPLSVFYIYYQQYYLRTSRELRRLDSITRSPIYSHFQETLGGLATVRGYSQQKRFSHINQCRIDNNMSAFYPSINANRWLAYRLELIGSIIILGAATLSVFRLKQGTLTAGMVGLSLSYALQITQTLNWIVRMTVEVETNIVSVERIKEYADLKSEA----PLIVE-GHRPPKEWPSQGDIKFNNYSTRYRPELDLVLKHINIHIKPNEKVGIVGRTGAGKSSLTLALFRMIEASEGNIVIDNIAINEIGLYDLRHKLSIIPQDSQVFEGTVRENIDPINQYTDEAIWRALELSHLKEHVLSMSNDGLDAQLTEGGGNLSVGQRQLLCLARAMLVPSKILVLDEATAAVDVETDKVVQETIRTAFKDRTILTIAHRLNTIMDSDRIIVLDNGKVAEFDSPGQLLSDNKSLFYSLCMEAGL 1511
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Match: gi|74997050|sp|Q54U44.1|ABCCC_DICDI (RecName: Full=ABC transporter C family member 12; AltName: Full=ABC transporter ABCC.12) HSP 1 Score: 824.698 bits (2129), Expect = 0.000e+0 Identity = 471/1283 (36.71%), Postives = 721/1283 (56.20%), Query Frame = 0
Query: 203 SLEDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRKQAEDKLVDFTSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLI------KHMDSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDELKVLATTTKEPPKREVRVPSEEVESPEETDNLIEETADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPET---GSDRTGFY----LGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAG 1472
S E+ ++ LS L FSW DG + + L+ +L K K W + + +P S F+ G I+L V FV P+I+ ++ K S E G++Y +++ ++++ + + + + ++R+ ++ +Y+K+++LSN AR S G++ N +S DAQR++E F + + + I+I + L+ ++ + GL + IP N +K + + + + D R+K+ +E+L +K++KLYAWE F +++ + R EIK++ R + + P +I VF Y + + L A KIF A++ NL++ PL P + +++ ++ KR+ +FL E+ I N P+ + M +T TW+ + L +N SLT +VG+VG+GKS+L+ + LGE+E + G++ ++GSIAYVPQQAWI N TL++NI+F +E Y KV+ C L+ D+ + D EIGE GINLSGGQKQRVS+ARAVYSDAD+Y+LDDPLSAVD+HVGK +F + +G L KT +LV + +N+L DN +VLK+G++ E G+Y +L+ F+ L +Y + T ++D+ K+ K E S++ + LI EE+ G V KVYW YV + G F + L+ L + ++WLS W + E+ G + TG LG+Y G+G+ +I+ R +A+ IH +L +++ PM+FFD P GRI+NRF+ D+D +D ++ ++ L+ ++++ P + P+ +++F +Q F+ S+ ++R E++T+S IF HFSET+ G+ SIRAY++Q + ++Q R+ NC + NRWLGLR++ LGNL+VFF+ IF L ++ +SP GL ++YAL I LN + + ET ++ERI +Y EA + D + WP G++ F + RYR GLD VLKGI E+++ EKIGI GRTGAGKSS+ L+LFR+IEA +G I IDG++IA+ GL LR + IIPQDPVLF+G LR NLDP D E+WS LD L + GL +++E GENFSVGQRQLI LARALLRK KILVLDEATA+VD +D LIQ+TIR +F +CT++TIAHRLNTI+D D+I V G+I+EF P LL N L + N+ G
Sbjct: 34 SPEENSNFLSNLTFSWADGFVIHCFRNVLQLSHLWDLASYDKSEYLAKKIAKSWEIEIQ----------KPKPSYLRAGFRAFGKLHCISLFFYSIYVGSQFVGPEILSRMVTFVVESKLGTSTEDPNMGYYYALIMFGTAMIGSFCNYQANRVTVRTGDRLRSIIVLDVYKKAIKLSNSARSNTSPGQIVNLISNDAQRMIEVFGILNNGLFALPQIIICLALLYEKIGWPTFVGLGLMLAAIPFNGLAAKKLTETRRILIGHTDGRVKVTSEILQAMKIIKLYAWEDSFAKKVLDRRNNEIKLLFSFTRYRTILIAMIGAIPTAASILVFSTYYGYNGS--LDAGKIFSALSYLNLLKIPLGFLPILIALGIQMQIASKRVTDFLLLPEMKEVQQID--NPSLPNGVYMKNSTTTWNKEKEDSFGLKNINFEAKGQSLTMVVGSVGSGKSTLVQAMLGELETIDGEIGIKGSIAYVPQQAWIINATLKENIIFGKELDEERYQKVLEVCALKRDIELFPQGDSVEIGERGINLSGGQKQRVSIARAVYSDADVYILDDPLSAVDSHVGKHLFHKCF---KGILSSKTVILVANQINYLPFADNTVVLKSGEIVERGTYYELINAKLEFASLLQEYGVDENTKGDDSDDDDDKKDDDKKEEKVEKPKQSDKDGT--------------LISEEEAEQGAVAGKVYWKYVTAGGGLLFLFAMILFLLETGSKTFTDWWLSHWQTESSERMESILLGEEPTGLTDDQNLGIYIGVGMASIIVTVVRTFSFFEYAVRAAHSIHHELFNALLKKPMSFFDQTPLGRIINRFTRDLDIIDNLIATSIAQFFTLMLSVLATLILISIIVPWLLIPLAPICILFFILQYFYRYTSRGLQRIEAITRSPIFNHFSETLNGVVSIRAYKKQQENILKNQKRLDDNNNCYLTLQAMNRWLGLRLDFLGNLIVFFSCIFITLKKDTISPSDVGLVLSYALSITSNLNQGVLQAADTETKMNSVERISQYIRGAVEAPQIID-DCRPSPDWPINGSIKFDNLVMRYREGLDPVLKGITCEIKAKEKIGIVGRTGAGKSSIVLALFRLIEASEGSISIDGENIAKFGLKDLRRNLAIIPQDPVLFSGTLRENLDPFNECPDHELWSILDDIQLSKVFKSTEEGLNSKVTENGENFSVGQRQLIVLARALLRKPKILVLDEATASVDGQSDSLIQATIRNKFSNCTILTIAHRLNTIMDSDKIMVLDAGKISEFDEPWTLLQNQNGLLTWLVNETG 1284
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|586962516|gb|AHK05646.1| (ATP-binding cassette transporter sub-family C member 1 isoform X6 [Tigriopus japonicus]) HSP 1 Score: 1850.48 bits (4792), Expect = 0.000e+0 Identity = 907/1475 (61.49%), Postives = 1130/1475 (76.61%), Query Frame = 0
Query: 8 FCRDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTWTRGR--ASTVSSKYGPLFLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFVGLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVEEWVLLITYVPIILGLFIAHCWVDIDPRAAEDLSLEDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRKQAEDKLVDFTS-PIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHMDSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDELKVLATTTKEPPKREVRVPSEEVES-PEETDNLIEET----ADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPK-VGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
FCRDPFFD++ VWNTTDPN+TQCM+DTLL+G+PC + LI S+IW++YQ R S +G LF AK L+++VN +GQ + GG D+LVPSE+ HY CLL + +A +Q +DK+L +H SPPLFLFWL L+ CE+ KLKIDIQ+ + T E WVLL++Y P+I + C DID A +S ED+AS LSLL FSW DGL+W+G + L LPKSPRS+NV NV+ F WR++ E V+F S RPF+ +W I + R A +VA+ ++LPFV+PQI+KLLI H+DS+E W+G+FYT+VLL S+ +ST+ FH YQQHL ISAIQMR++++GA+Y+KSL+LSN ARR ++VGE+TNYMSVDAQR+V+TFPY M LIM+PLTI++AMYFLF E+ ++SLAGL + I IPIN G K ++LQV QL+AKD RLKLMNE+LMG++VLKLYAWE PFM RI +IR +E+KI+++C RLWAF+NF++ +PILVTI VF +YV +DP+HVLTADKIFV+++LFNL+R PLV FPFTL+E++K+ VSLKRIN +LNA+EI+S NV H D A+E+ + TLTWD + P L +++ IP GSL A+VG VG+GKSSLLS+ LGEME +SG GSIAYVPQQAWIQNM+L+DNILFD+ F T Y +V+R CQLE DLAILK+ D TEIGENGINLSGGQKQRVSLARAVYSDAD+YLLDDPLSAVDAHVGK+IFTQV D+ +G KDKTR+LVTHN++ L K+DNIIV+K G+V E GSYQKLLADG AFSEFL Y AT EP + + VE E+ N I+++ + DLI++E+ + GRV VYW YV S S+FF VV L+ + S + A +NYWLS WAD N+ P+ + + ++LG+YG GVVQLIL+FSREL++ + CA AS+++H+KLL V RSPM+FFDTNPTGRI+NRFSSD+D VDQ +P GLSD +W FD+LS++VV+C STP F VI+PL L+Y+F+QR F+ S+Q+KR ES++KS I+A+FSETITG ASIRAY +Q RF ES+ RVQKC CTFL SANRWLG RVE+LGNL+VFFAAIFA+L+R+ LSPG+AGLSITYAL IMD LNW+IRMLCELETNSVALERI+EYTHN+ EA+W+ P D K + TWP G V F S A RYR GLDLVLKGI ME++ EKIGICGRTGAGKSS TL+LFRI+EA G I IDGQDI+++GLH LRSRITIIPQDPVLFTG+LRFNLDP +HSD +WSAL+HAHLK HIS K GL HEI+EGGENFSVGQRQLICLARALLRKTKIL++DEATAAVDL TDDLIQ+TIRREF+ CTVITIAHRLNTI+DCDRIAVF+ G++AE+ P +LL+ SAL M DAGL
Sbjct: 16 FCRDPFFDVNTVWNTTDPNLTQCMQDTLLIGLPCCVLLITSVIWNLYQYVIEFRHVTSLEERSFGALFFAKLVLNLILIVNAVGQLWNLANLNGGWDQLVPSEIVHYACLLGILFVANVQVIIDKWLLSHTSPPLFLFWLVLIFCEVAKLKIDIQTIVEGHSTWEHWVLLLSYFPVIFVQLVLSCISDIDKTTALFVSPEDRASFLSLLTFSWFDGLIWKGARQILTQDILPKSPRSINVGHNVQDFLNLWRQKVEFLGVNFASFQERPFIGIWSIFIRTQWVRVTFAFLVAIIHLVLPFVNPQILKLLINHVDSDEEAWKGYFYTVVLLISATVSTITFHVYQQHLSISAIQMRSAIIGAIYRKSLKLSNHARRQFTVGEITNYMSVDAQRVVDTFPYTMALIMAPLTIIVAMYFLFLEVGISSLAGLAILLILIPINGIGGKWAERLQVNQLKAKDKRLKLMNEVLMGMRVLKLYAWENPFMDRIKKIRDSEVKILRLCARLWAFMNFTFTGAPILVTIAVFALYVLIDPSHVLTADKIFVSLSLFNLIRIPLVMFPFTLVETIKLIVSLKRINTYLNANEINSANVSHNM-DCESDAVELKDLTLTWDEPES--PSLMNISIQIPKGSLVAVVGEVGSGKSSLLSAILGEMEVVSGSAHAVGSIAYVPQQAWIQNMSLKDNILFDKAFVRTKYDEVVRCCQLESDLAILKNADSTEIGENGINLSGGQKQRVSLARAVYSDADLYLLDDPLSAVDAHVGKSIFTQVFDNQQGLFKDKTRILVTHNISVLSKVDNIIVMKGGRVVEIGSYQKLLADGAAFSEFLNIYAQE--------------ATEKHEPVDDVNQFENSHVEQISEQKINQIQDSTLAESGDLIKDERAMVGRVKWSVYWHYVNSSRISRFFLVVCLHAIGSALLASSNYWLSIWADANQNDPDEANTQIAYFLGIYGAFGVVQLILEFSRELMYFLGCATASQIMHEKLLYHVFRSPMSFFDTNPTGRIINRFSSDVDVVDQRIPQGLSDTMWSIFDSLSIVVVICVSTPSFGYVILPLVLLYYFIQRMFISTSRQVKRLESLSKSPIYANFSETITGTASIRAYGEQIRFNQESENRVQKCAQCTFLIASANRWLGTRVEILGNLIVFFAAIFAILARDTLSPGVAGLSITYALNIMDNLNWLIRMLCELETNSVALERIIEYTHNDQEADWESPNDSKELSQTWPNRGKVEFDSLAIRYRKGLDLVLKGISMEIQGQEKIGICGRTGAGKSSFTLALFRILEADSGEIRIDGQDISKIGLHALRSRITIIPQDPVLFTGDLRFNLDPTGLHSDSSLWSALEHAHLKSHISSFKDGLDHEINEGGENFSVGQRQLICLARALLRKTKILIMDEATAAVDLATDDLIQATIRREFKDCTVITIAHRLNTIMDCDRIAVFNQGEVAEYAPPRDLLSIDNSALSLMAKDAGL 1473
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|586962506|gb|AHK05641.1| (ATP-binding cassette transporter sub-family C member 1 isoform X3 [Tigriopus japonicus]) HSP 1 Score: 1536.55 bits (3977), Expect = 0.000e+0 Identity = 771/1504 (51.26%), Postives = 1046/1504 (69.55%), Query Frame = 0
Query: 8 FCRDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTWTRGRASTVSSKYGPL---FLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFVGLALLQTAVDK-FLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVEEWVLLITYVPIILGLFIAHCWVDIDPRAAEDLSL-EDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRKQAEDKLVDFTSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHMDSN-EPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDELKVLATTTKEPPKREVR---------VPSEEVESPEETDNLI-----EETADD-----------------LIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLP-LDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
FC DPFF+ + W+T DPN+TQCMRDT+LVGVPC +FL+ W+I+Q + R G + F+ K TLV++ N + + ++GGS + SE+FHY L + + L+Q +D+ FL A S PLF FW L + IP K +I + + S E+W L+++Y P++L F+ +CW D+ ++L+ ED AS SLL FSWL L+W+G K+PL K LPK P+++ V NV F W K+ V+F + FVS++P+L+K H R L+ + ++ L+ F+SPQI+KLL+ H+ S + W+G+ Y + L S + T +FH Y Q+ + +IQMR+S++G +++K+ RLSN +++ Y+ GE+TNY+SVDAQR+V+T PY+ L +PLTI +A YFL+ EL S AG+ + +PINLF K V++LQ QL+ KD R+KLM+E+L GIKVLKLYAWE PFM+R+ IR EIKI++ RL A INF++ SPILVTI VFG+YV +D + LTA+KIFV+++L N+ R PL+ FP+ LIE +K+ VSLKRIN+FLNA E++S+ V D + +A+E T A+ TW+ +G D I+ +NL IP SL A+VG VG+GKSSLLS+ LGEMEK SG + GSIAYVPQQAWIQNMTL+ NILF+ ++ ++ Y +V+ CQL+ DL ILK D TEIGENGINLSGGQKQRVSLARAVYSDAD+YLLDDPLSAVDA VGK IF +VL + GCL+DKTRVLVTHN+N L ++D+I+V+++GK+AESGSY+KL DG AF+EFL +T + V E+ + ++ + V +P +S EE LI EE D+ L+ EE + G V V+ TY + IG S+F +V L+ + H+ ANYWLSRWAD N P+ ++ YLG Y +G+V++ +F+ E LH +SCA ASK+IH++LL+ VM SPM+FFDTNP GRI+NRFS D+D +DQ +P+ + D +WC D +S+IV++ STP F+ IIPLG+++ QR+++ S+Q+KR ++V+KS + AHFSETITG ASIRAY+QQDRF+ E + R++ C +L VS NRWLG+R+E+LGN++VFFAA+F +L R +LSPG+AGLSI+Y+L IMD L WM+RM+CELETN VALERILEYT N EA W++P +D + WP+EG V K+Y TRYR GLDL L GID+EV++++ IGICGRTGAGKSSL+L+LFR+IEA G I ID DI+ LGLH LRS +TIIPQDP+LFTG++RFNLDP + SD ++W+AL H HLK + +L GL H++SEGG NFS+GQRQLICLARALLRKT ILVLDEATAA+DL TD+LIQ+TIR EF+ CTV+TIAHRLNTI+D D+I V S G++ E+ SPA LL++ S M DAGL
Sbjct: 2 FCPDPFFNSSITWDTDDPNLTQCMRDTVLVGVPCGVFLLLVPFWNIHQFQSYSRRDVFPRIRGNISVRFVLKIVSTLVLIANTIVRI----RNLGGSRTIFGSEIFHYGLLCFTLFVVLVQEFIDRRFLCAIKSLPLFSFWFVLSLASIPGFKYEID-QALESSQAEDWALILSYYPLVLAQFLLNCWSDLGGITDDELAPPEDSASYPSLLTFSWLHRLIWKGFKSPLTLKQLPKPPKTILVATNVLRFLNAWTKKVASMGVNFETEGTRFVSVFPVLWKCHWPRILLCIGLSASHYLIGFISPQILKLLVNHVASQTDQTWKGYLYVVALFLESCVWTFSFHMYCQNASVLSIQMRSSMMGMVFRKAFRLSNSSKKHYTTGEITNYVSVDAQRLVDTMPYLSNLWCAPLTIGLAQYFLYQELGPVSFAGIGTLFLLMPINLFTGKWVERLQADQLRNKDERIKLMSEILGGIKVLKLYAWEKPFMKRLLNIRDNEIKILQFSARLRALINFTFFCSPILVTISVFGLYVLVDCQNTLTAEKIFVSMSLLNMTRYPLIMFPWALIEGIKLIVSLKRINKFLNAKEMNSSLVTKEVIDPN-NAVEFTSASFTWN--EGSDAIIQDINLKIPSRSLVAVVGMVGSGKSSLLSALLGEMEKTSGSIGRVGSIAYVPQQAWIQNMTLKQNILFENDYEASRYHQVLDKCQLKQDLEILKSGDETEIGENGINLSGGQKQRVSLARAVYSDADLYLLDDPLSAVDALVGKNIFDEVLANENGCLRDKTRVLVTHNLNVLPRVDHIVVMRHGKIAESGSYEKLKKDGGAFAEFLENFTFDKVQEEIVSASPSTSVPIRQQSSESNVSPFGSPKFQGIPYVRHDSWEEAKQLIRPGDNEERLDEREPLVQPLESIHSGNETLLMEESSFQGSVKWSVFLTYFKDIGFSKFLLIVILFVTSQSCHSFANYWLSRWADVNHKCPDKSAENILTYLGTYSALGLVEIGTEFAYEFLHFLSCAYASKLIHERLLERVMHSPMSFFDTNPMGRILNRFSVDVDSLDQNIPSMIRDFLWCMCDLVSIIVIITYSTPWFSVTIIPLGVVFMMFQRYYIATSRQLKRLDAVSKSPVLAHFSETITGAASIRAYRQQDRFIEEFETRLETNIKCYYLMVSCNRWLGVRMELLGNVIVFFAALFVILKRSSLSPGVAGLSISYSLNIMDALTWMVRMVCELETNFVALERILEYTDNPQEAPWEVPAIDDNLPQNWPSEGKVCMKAYKTRYREGLDLALNGIDLEVKAHQSIGICGRTGAGKSSLSLALFRVIEACHGTIFIDDVDISTLGLHRLRSCLTIIPQDPILFTGSVRFNLDPTQTSSDFDLWNALGHVHLKPIVENLSEGLDHQVSEGGINFSLGQRQLICLARALLRKTTILVLDEATAAIDLETDNLIQATIREEFKSCTVLTIAHRLNTIMDNDKIVVLSQGRVLEYDSPAALLSDENSTFSDMAKDAGL 1497
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|586962518|gb|AHK05647.1| (ATP-binding cassette transporter sub-family C member 1 isoform X7 [Tigriopus japonicus]) HSP 1 Score: 1374.38 bits (3556), Expect = 0.000e+0 Identity = 722/1522 (47.44%), Postives = 997/1522 (65.51%), Query Frame = 0
Query: 8 FCRDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIY-------QTWTRGRASTVSSKYGPLFLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFVGLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVEEWVLLITYVPIILGLFIAHCWVDIDPRAAEDLSLEDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRKQAEDKLVDFTSPIRPF----VSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHMDSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDE-----LKVLATTTKEPPKREVRVP---------------SEEVESPEETD-------------------------NLIEETADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
FC+DPF++ L WNTT+P++TQCM+DTLL GVPC+ FL+ +W IY Q++ R S + +G FL K T LV++ NL+ Q + H D+ SE+F + ++ + L L+ V+K+ H SPP+FLFW LL+ +IP +K ++ V W+L TY P+ L I HCW D A D E AS + + ++W+D L+W G K PL +P P+ + V+ ++ F QW K+ F P V + +LF +G R + ++ L FV P ++KLLI+H+ S+E W+GF Y I++ ++ L ++ H + Q ISA Q+R SL +Y+K+L+LSN AR+ +++GE+TN++S D Q + T PYM + ++P+ I+IAM+FL+ EL + G+ + A+ +P+N + S +KK++ Q++AKD R+KLMNE+L G++VLKLYAWEIPFM RI IRLTE+K++K +++A NF+ S P L+TI FG+Y P +LTADKIFV+IALFN++R +V P+ ++ +K FVSLKRI +FLNA+E+D + + +AIE+T+ + T +++ L +N+ I GSL A+VG VGAGKSSLLS+ LGEMEK GQ+ G++AYVPQQAWIQNMTL++NILF++ F + Y + + C L+ DL IL D TEIGENGINLSGGQKQRVS+ARAVYSD+D+YLLDDPLSAVDAHVGK +F +V S G LKD+TRVLVTHNV+FLD+MD I+V++NG +AE GSY +L AFSEFL QY + EV D L+ ++ P R R+ S ++P D + + A L+++E+ + G+V KVY +Y++ +G LY + + + ++YWLS WAD N A P T +D+T FYLGVY GIG +Q+I+ RE++ ++CA AS +IH +LL V+ SPM+FFDTNP GRIVNRFS+DI VD +P +S + C +V+ ++C S PIF +VI+PL +Y+ +QR ++ ++Q++R ES+ S IFAHF E++ G+ SIRAY+Q++RF+ ES+ RV K ++ V NRWLG+R+E L NLVVFF A+FAVLSR +SPG+ GL+IT++L + LNW+IR +C++ET++VALERILEY+ N EA+W LP D K +P EG + F Y TRYR GLDLVLK + M ++ EKIGICGRTGAGKSSLTL+LFRIIE V G+IL+DG D+ LGLH LRS +TIIPQDPVLFTGN+RFNLDP E ++D +IW AL+HA+LK HIS L GL HE+SEGG+NFSVGQRQL+CLARALLRKTKIL+LDEATAAVDL TDDLIQ+TIR+EF CTV+TIAHRLNTILD DR+AVFS G++ E SP L+ S + + +AGL
Sbjct: 21 FCKDPFYNSSLTWNTTNPDITQCMQDTLLTGVPCLFFLLTEPLWIIYKIYYYSIQSFPISRDS--RNTWGWKFLIKVTLNLVLITNLILQI-WNQSH----DEFYGSEVFRFMAMIGTIVLMLVAMGVEKWNRIHTSPPMFLFWGLLLLVKIPTVKDHVEHLTNDPSDVLYWILAFTYYPVFLLQIIFHCWADHSNMDASDKPPESVASFPATIFYTWIDPLIWAGLKAPLTLDQVPPQPQYVTVSFVIQDFLNQWSKKVSKIEKTFIKDRDPAGEKKVKILDVLFATYGKRFFLIFLLGTVNFTLIFVGPIMLKLLIQHVQSDEEAWKGFAYVILIFVNASLQSLLNHQFLQQTVISAQQIRASLSSMIYRKTLKLSNLARKKFTMGEITNFISTDIQTLGMTIPYMNNVWVAPMKIIIAMFFLYEELKSVAFIGVAIMAVLLPLNYWSSVIIKKMRKNQMEAKDGRIKLMNEVLKGMRVLKLYAWEIPFMSRINAIRLTEVKLMKSLAKVYAISNFTLNSGPTLITIACFGLYTVFQPGEILTADKIFVSIALFNIIRMSMVMLPWAIVALLKAFVSLKRIADFLNANELDP-EAVGKETEHEENAIEITKGSFT-WTEEEEQTTLKDINVQIRKGSLVAVVGVVGAGKSSLLSAILGEMEKTDGQINQSGTLAYVPQQAWIQNMTLKNNILFEKPFETGRYKRTLEACALKDDLDILISGDETEIGENGINLSGGQKQRVSVARAVYSDSDVYLLDDPLSAVDAHVGKHLFDKVFSSKSGILKDRTRVLVTHNVSFLDQMDLILVMRNGTIAERGSYSQLKESKGAFSEFLEQYANQATKEEVTEDHEKNKHLQAKPIKARQIPPRTRRMSQTLSCSPASPFIKYLSTSADAPLPDDILAEEEEAILEETIEESAVSSRRGSKVNDPLAGRLVDDEEAMIGKVNWKVYLSYMKDLGNIISVISFLLYMVGQGLESGSSYWLSFWADSNGADPATANDKTPFYLGVYSGIGALQIIIMIVREIVLFIACADASNLIHARLLSKVVSSPMSFFDTNPIGRIVNRFSADIGTVDDGIPFQISLLFECFTSIATVLALICYSLPIFMTVILPLAFMYYGIQRCYISTTRQLQRIESIVISPIFAHFGESLNGVQSIRAYKQEERFILESEKRVDKGVQLHYMCVMMNRWLGVRIEFLANLVVFFVALFAVLSRGTISPGLTGLAITFSLNVTGMLNWLIRAVCDMETDAVALERILEYSENPQEADWSLPEDDKFCD-FPMEGQIEFSKYETRYREGLDLVLKDVSMRIQPKEKIGICGRTGAGKSSLTLALFRIIEPVSGKILVDGIDVNTLGLHKLRSGLTIIPQDPVLFTGNVRFNLDPTEENTDTQIWQALEHANLKAHISSLTNGLDHEVSEGGDNFSVGQRQLLCLARALLRKTKILILDEATAAVDLETDDLIQATIRKEFADCTVLTIAHRLNTILDSDRVAVFSEGKLVELDSPQSLMDKHDSVFRGLAKNAGL 1532
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|1133439954|ref|XP_019876350.1| (PREDICTED: LOW QUALITY PROTEIN: multidrug resistance-associated protein 1-like [Aethina tumida]) HSP 1 Score: 1251.11 bits (3236), Expect = 0.000e+0 Identity = 683/1529 (44.67%), Postives = 960/1529 (62.79%), Query Frame = 0
Query: 8 FCRDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTWTRGRASTVSSKYGPLFLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFVGLALLQTAV----DKFLGAHISPPLFLFWLALLICEIPKLKIDI-QSRMVASGTVEEWVLLITYVPIILGLFIAHCWVDIDPRAAEDLSLE-----DKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKA----FTKQWRK-----------------QAEDKLVDF--TSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHMDSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTS-----------NPVTSEVETDELKVLATTTKEPP---------KREVRVPS-----EEVESPEETDNLIEETADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALA---NYWLSRWADHNE-AHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMA-FFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
FC F+D +L WNTTDP++T+C T+LV PC S++ Y T ++ R + L ++K T + V + + D VP + P + + L+ L +AV +K G S FLFWL L +C + + +I Q+++ ++V + Y P++L + + +C+ D P+ + +E + AS S L+F+W D L W G K PL+ ++L MN D+ K F K W K + + VDF +S +P S+ P L ++ G + L + LL FVSP I+ LLI + + W+G+ Y ++LL ++ + T+ Y + I +++R +L+ +Y+K+L++SN AR+ +VGE+ N M+VDAQ+ V+ Y+ + +PL I ++MYFL+ EL + LAGL + I IP+N F + VK LQ++Q++ KD R+KLMNE+L GIKVLKLYAWE F +++ +IR EIK++K + A +F + +P LV++ F YV +D ++VL A+K +V+I+LFN++R PL P + V+ +VS+KRIN+FLN E+D NV H N++ P E +W G +P+L +N+ + GSL A+VGTVG GKSSL+ + LGEMEK SG+V GSIAYV QQAWIQN TLRDNILF ++F Y V++ C L+PD +L D+TEIGE GINLSGGQKQRVSLARAVY+DA+IYLLDDPLSAVD+HVGK IF QV+ T G L KTRVLVTH + +L + D I+V+KNG+++ESG+YQ+LL +F+EFL+Q+ S + V E++T E K + + E +R+ + S + +S E++ ++ ++ + LIE EK+ G V +VY Y++SIG FF L V + N WL RWAD + A+ + + YLGVYG +G+ Q+I F L + A+K +H LL+ +M+ P F+D P GRI+NRFS D+D +D V+P L I C F + +VV+ +TP+F VIIP+GL+Y+F+QRF+V S+Q+KR ESV++S I++HF E+ITG +IRA+ Q++RF+ ES+ +V + C + ++ +NRWL +R+E++GNL++FFAA+F VL ++NL PG+ GLS+TYAL I TLNW++RM ++ETN VA+ERI EY EA W++P WP GAV FK+YA RYR GLDLVLKG+D V EKIGI GRTGAGKSSLTL+LFRIIEAV+G I IDG I++LGLHTLRSR+TIIPQD VLF+G+LR NLDP + HSD E+W +L+HAHLK + L G+ H+++EGGEN SVGQRQLICLARALLRKTK+LVLDEATAAVDL TDDLIQ TIR EF++CTV+TIAHRLNTI+D DR+ V GQI EF SPA LL N S +M DAGL
Sbjct: 9 FCGSDFWDYNLSWNTTDPDLTKCFERTVLVWFPCAFLWTFSILEIYYITNSKKR----DIPWNWLNVSKLVVTAALCVLSATDLVTSVKNAKSEDGSVPKVDIYTPVIKI---LSFLLSAVLLVFNKKHGLQTSGLQFLFWLLLGLCGAVQFRTEIRQAQVQVPEPYYDYVSYLIYYPLVLIMLLLNCFADKSPKHTQYAKVERPCPEEGASFPSRLLFAWFDTLAWLGFKKPLEAQDL----WDMNPQDSAKEVVPLFEKYWHKTLQKCESSSSPHTRASFKPDSASVDFVNSSKKKP-ASILPALVESFGPTFFFGASLKLVQDLLTFVSPIILGLLITFVKEQQETWKGYMYAVLLLATATVQTIILSQYFNRMFIVGMRIRTALVATIYKKALKISNAARKQTTVGEIVNLMAVDAQKFVDLTAYLNMIWSAPLQIFLSMYFLWNELGPSVLAGLAIMIILIPVNGFIANKVKVLQIKQMKNKDERVKLMNEILSGIKVLKLYAWEPSFEKQVLQIRAKEIKVLKEAAYMNAGTSFIWSCAPFLVSLVTFATYVLVDESNVLDANKAYVSISLFNILRFPLSMLPMMISNMVQTWVSVKRINKFLNEEELDPNNVTHDQNEVDPIIFE--NGNFSW----GDEPVLKNINIRLTKGSLNAVVGTVGCGKSSLIYASLGEMEKKSGRVNTVGSIAYVSQQAWIQNATLRDNILFGKKFDQKIYDNVVKACALKPDFDMLPAGDQTEIGEKGINLSGGQKQRVSLARAVYADAEIYLLDDPLSAVDSHVGKHIFEQVIGPT-GLLGKKTRVLVTHGITYLPQTDKILVMKNGEISESGTYQELLNKKGSFAEFLLQHASEGPAEDLDEIESQVPDEIKT-EFKRMRSHVSESEGSEKANGSLQRQRSIDSSGKERQRSKSIEDSKSVSKKEGEKLIEAEKSETGSVSWQVYKYYLKSIG---FFLTAATILLNMVFQGFSIGSNVWLGRWADDKDLANGTQNTQKRDMYLGVYGALGIGQVIAIFLSVLALYVGTLNAAKSLHRLLLENIMKVPTTTFYDVTPVGRILNRFSKDVDTLDNVLPMTLRGWITCFFSVIGTLVVISYTTPLFIIVIIPIGLLYYFIQRFYVATSRQLKRLESVSRSPIYSHFGESITGAQAIRAFGQEERFITESERKVDQNQVCYYPSIISNRWLAVRLEMIGNLIIFFAALFGVLGKDNL-PGLVGLSVTYALQITQTLNWLVRMTSDVETNIVAVERIKEYGEATQEAAWEVP-SKNPSSLWPEVGAVEFKNYAVRYRPGLDLVLKGVDFSVNGGEKIGIVGRTGAGKSSLTLALFRIIEAVQGDIYIDGVKISELGLHTLRSRLTIIPQDAVLFSGSLRMNLDPFDKHSDDEVWRSLEHAHLKDFVKGLPSGIQHQVTEGGENLSVGQRQLICLARALLRKTKVLVLDEATAAVDLETDDLIQRTIRTEFKNCTVLTIAHRLNTIMDSDRVLVLDKGQIVEFDSPATLLLNSKSIFYSMCKDAGL 1512
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|1080053916|ref|XP_018568578.1| (multidrug resistance-associated protein 1 isoform X9 [Anoplophora glabripennis]) HSP 1 Score: 1242.25 bits (3213), Expect = 0.000e+0 Identity = 680/1528 (44.50%), Postives = 954/1528 (62.43%), Query Frame = 0
Query: 8 FCRDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTWTRGRASTVSSKYGPLFLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFV-GLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDI---QSRMVASGTVEEWVLLITYVPIILGLFIAHCWVDIDPR-----AAEDLSLEDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWR-----------------KQAEDKLVDFTSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHMDSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYT----------------------SNPVTSEVETDELKVLATTTKEPPKREVRVPSEEVESPEETDNL-------IEETADD-----LIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHN--EAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
FC F++L+L WNT DP+ T+C T+LV +PC S + Y ++ R + + L ++K T ++ + L + SD +V S + P + +F L+ L ++ G S LFLFWL L +C + + +I Q + G+ ++ + Y P++L +F+ +C+ D PR +E E+ AS LS L+F+W D L W G + PL+ +L + + V F K W+ K D + S + S+ P L K+ G ++ L + +L FVSPQI+ +I ++ + W+G+F+T +L ++ + T+ Y + I +++R +L+ +Y+KSL++SN AR+ +VGE+ N MSVDAQ+ +E ++ + +PL I++++YFL+ EL + LAGL V I IP+N F + VK LQ++Q++ KD R+KLMNE+L GIKVLKLYAWE F ++ +IR EIK++K L A +F + +P LV++ F +V +D +VL A+K +V+I+LFN++R P+ P + V+ +VS+KRIN F+N+ E+D NV H + + P IE + T +W G DPIL +N+ + +LTA+VGTVG+GKSSL+S+FLGEM+K+SG+V G IAYV QQAWIQN TL+DNILF ++F Y KVI C L+ D +L D+TEIGE GINLSGGQKQRVSLARAVYSDADIY LDDPLSAVD+HVGK IF +V+ +G L+ KT+VLVTH + +L + D+IIV+K+G+V+ESG+YQ+LL AF+EFL+Q+ S VT + +V + ++ R + + +S + TD IEE+ +D LIE EK G V VY Y++SIG F + L + +N WL WA+ + + + R YLGVYG +G+ Q + EL + C A+K +H L GV RSPM FFDT P GRI++RFS DI+ VD +P +SD ++C F+ + I V+ +TP+F VI+P+GL+Y+F+QRF+V S+Q+KR ESV++S I++HF ET+TG+ +IRAY QQ+RF+ ES+ +V C + +V +NRWL +R+E++GNL++ FA++FAVL +E P + GLSITYAL I TLNW++RM ++ETN VA+ERI EY EA W++P + WP G+V F +YA RYR GLDLVLKG+D ++ EK+GI GRTGAGKSSLTLSLFRIIEA +G+I IDG +IA+LGLHTLRSR+TIIPQD VLF+G LR NLDP + HSD E+W AL+HAHLK +S L L HE+SEGGEN SVGQRQLICLARALLRKTK+LVLDEATAAVDL TDDLIQ+TIR EF+ CTV+TIAHRLNTI+D DR+ V GQI EF +PA LLANP + M DAGL
Sbjct: 9 FCGGEFWNLNLTWNTNDPDFTKCFEKTVLVWIPCFFLWTFSSLEVYYLIKSKRR----NIPWNWLNISKLVVTGILSILCLSDLV-NAFKSADSDNVVYSVDIYSPLIKLFTFALSALLVVYNRKHGMPSSGLLFLFWLLLGVCGAVQFRSEIRRAQRSEIPPGSKYFYISYLIYYPLVLLMFLLNCFADKPPRESKYPKSERPCPEENASFLSRLLFTWFDSLAWTGFRKPLEATDLWDMKPEDSAKEIVPLFEKHWQNTLDKSGSYSPTQNAQFKSDVDHVAFVNSKKKKEASVLPALVKSFGPTFAFGALLKLMQDILTFVSPQILGYIITYVRKGQYEWRGYFFTALLFITATIQTLLLAQYFNRMFIVGMRIRTALISTIYRKSLKISNSARKETTVGEIVNLMSVDAQKFIELTAFLNMIWSAPLQIILSLYFLWYELGPSVLAGLAVMIILIPVNGFIANKVKTLQIKQMKNKDERVKLMNEILSGIKVLKLYAWEPSFENQVLKIRNKEIKVLKSAAYLNAGTSFIWSCAPFLVSLVTFATFVLVDENNVLDANKAYVSISLFNILRFPMSMLPMMISNLVQTYVSVKRINRFMNSEELDPNNVTHDSFEADPLIIE--KGTFSW----GDDPILKNINIRLKKQTLTAVVGTVGSGKSSLISAFLGEMDKVSGRVNTVGRIAYVSQQAWIQNATLKDNILFGKKFDKVLYNKVIEMCALKADFEMLPGGDQTEIGEKGINLSGGQKQRVSLARAVYSDADIYFLDDPLSAVDSHVGKHIFDKVI-GPKGMLRYKTKVLVTHGITYLPQTDSIIVIKDGEVSESGTYQELLDKKGAFAEFLLQHITEDVDTDDDLDEIKDQLVGTALSEEVTRRLSRHRSRVSESHSECGSDRILNGSLQRQKSSDSTDKSLRRRAGSIEESKNDSPKGKLIEIEKAETGSVSWDVYKHYLKSIGLFLTFATILLNMVFQGFSIGSNVWLGVWANDSSLNVNGTVNTARRDLYLGVYGALGIGQAVTSVFSELAPGLGCVAAAKGLHQLLTSGVFRSPMTFFDTTPLGRILSRFSKDIEVVDNSLPWYVSDGVYCFFEVIGTIAVISYTTPLFMLVIVPIGLLYYFIQRFYVATSRQLKRLESVSRSPIYSHFGETVTGVQAIRAYGQQERFISESEYKVDLNQVCYYPSVISNRWLAVRLEMIGNLIILFASLFAVLGKEQ-DPSLVGLSITYALQITQTLNWLVRMTSDVETNIVAVERIKEYGEAPQEAPWEIP-NKNPSSAWPEHGSVEFNNYAVRYRPGLDLVLKGVDFHIKGGEKVGIVGRTGAGKSSLTLSLFRIIEAAQGQICIDGVNIAELGLHTLRSRLTIIPQDAVLFSGTLRMNLDPFDKHSDEEVWRALEHAHLKVFVSGLAAALNHEVSEGGENLSVGQRQLICLARALLRKTKVLVLDEATAAVDLETDDLIQTTIRTEFKTCTVLTIAHRLNTIMDSDRVIVLDKGQIVEFDTPANLLANPNTIFHGMCRDAGL 1522
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|642933793|ref|XP_008197317.1| (PREDICTED: multidrug resistance-associated protein 1 isoform X4 [Tribolium castaneum]) HSP 1 Score: 1241.48 bits (3211), Expect = 0.000e+0 Identity = 686/1533 (44.75%), Postives = 954/1533 (62.23%), Query Frame = 0
Query: 8 FCRDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTWTRGRASTVSSKYGPLFLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCL-LVFVGLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVEE-------WVLLITYVPIILGLFIAHCWVDIDPRAAEDLSL-----EDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWRK--------------QAEDKL----VDF-TSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHMDSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSEVETDELKVLATTT---KEPPKREVRVPSEEVESPEET-------------------------DNLIEET----ADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWA--DHNEAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSR-ENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
FC F++ L W+T DP++T+C T+LV VPC S + Y ++ R + L ++K T V+ V + S+ V + P + L+ GL+ + ++ G S FLFWL+L IC Q R G+ EE ++ + Y P++L + +C+ D PR +E L E+ +S LS L+FSW D L W+G + PL +L + ++ V F K W++ +A KL VD S + S+ P L K G + ++ L + LL FVSP I+ LLI+ + +NE W+GF Y L ++ + T+ Y + + +++R +L+ A+Y+K+LR+SNKAR+ +VGE+ N MSVDAQ+ ++ Y+ + +PL I++A+YFL+ L A LAGL V I IP+N + + VK LQ++Q++ KD R+KLMNE+L GIKVLKLYAWE F ++I +IR EI+++K + A +F + +P LV++ FG YV +D ++L A K FV+++LFN++R PL P + V+ VS++RIN+F+NA E+D T+V H +N+ +P IE WD + +L +N+ I SL A+VG+VG+GKSSLLS+FLGEM+K SG+V G+IAYV QQAWIQN TLRDNILF + F + Y KV+ C L PD A+L D+TEIGE GINLSGGQKQRVSLARAVY+++DIY LDDPLSAVD+HVGK IF +V+ EG L+ KTRVLVTH + +L + D IIVLK+G+V+E G+YQ+LL AFSEFL+Q+ + E E D LK + T +E K+ R S ES ET + +EE + LIE EK G V VY Y++SIG + L L +N WL WA D T + + FYLG+YG +G+ Q I+ +L + C AS +H +L+GV+R+PM FFDT P GRI+ RFS D++ +D +P G++D ++C F+ L +VV+ STPIF +VI+P+G++Y+F+QRF+V S+Q+KR ESV++S I++HF ETITG+ +IRA+++QDRF+ ES+ RV C + ++ +NRWL +R+E++GNL++FFAA+F+VL R E+ + G+ GLS+TY+L I TLNW++RM ++ETN VA+ERI EY EA W++P + WP G V F YA RYR GLDLVLKG++ + EK+GI GRTGAGKSSLTL+LFRIIEA +G ILIDG +IA LGLHTLRSR+TIIPQD VLF+G LR NLDP + HSD E+W AL+HAHLK + L GL+HE++EGGEN SVGQRQLICL+RALLRKTK+L+LDEATAAVDL TDDLIQ TIR EF++CTV+TIAHRLNTI+D DR+ V +G+I EF SP+ LL S +M DAGL
Sbjct: 9 FCGSEFWNSTLTWHTNDPDLTKCFERTVLVWVPCAFLWTFSSLEVYYILHSKRR----DIPWNWLNVSKLLGTAVLFVLTVTDLVTAVNSASSSESDVYKVDIYTPVIKLLSFGLSAVLLVYNRKYGLCTSGLQFLFWLSLAICGA------FQYRTELRGSQEEIPESRYSYISYLIYYPVVLVMLFLNCFADRSPRRSEYPKLKNPCPEENSSFLSRLLFSWFDPLAWRGFRRPLVDSDLWDMKPEDSASEVVPTFEKHWKRILQKCESNSPTRQTRASYKLDSARVDIVNSSTKKQASILPALVKAFGPTFIFGALLKLIQDLLTFVSPHILNLLIQFVKNNEEQWKGFLYAGALFVTATIQTIVLSQYFNRMFVVGMRIRTALVSAIYKKALRVSNKARKESTVGEIVNLMSVDAQKFIDLTAYINMIWSAPLQIILALYFLWNILGPAVLAGLAVMIILIPVNGYIANKVKVLQIKQMKNKDERVKLMNEVLSGIKVLKLYAWEPSFEKQILKIRTKEIQVLKEAAYMNAGTSFIWSCAPFLVSLVSFGTYVMVDEHNILDASKAFVSVSLFNILRFPLSMLPMMISNLVQAMVSIQRINKFMNAEELDPTSVTHDSNESAPLVIE--NGCFNWDEEQ----VLKNINIRIEKKSLCAVVGSVGSGKSSLLSAFLGEMDKTSGRVNTVGTIAYVSQQAWIQNATLRDNILFGKSFDKSLYDKVVEACALNPDFAMLPAGDQTEIGEKGINLSGGQKQRVSLARAVYANSDIYFLDDPLSAVDSHVGKHIFDKVI-GPEGLLRHKTRVLVTHGITYLPQTDKIIVLKDGEVSEGGTYQELLDKKGAFSEFLLQHINEVEEDEEELDVLKSQLSGTAVSEEINKKLSRHRSRVSESVSETGSDQTSLSLQRQKSVESADKSLRHRSSSVEEAKKVKGEKLIEVEKAETGSVKWIVYKHYLKSIGVFLTVATILLNMLFQGFSIGSNVWLGVWADDDTVVVDNVTDTGKRDFYLGIYGALGIGQAIMSLFADLAPQLGCCYASIALHQVMLRGVLRAPMLFFDTTPLGRILGRFSRDVETMDSSLPWGMTDGVYCLFEVLGTLVVISVSTPIFIAVIVPIGILYYFIQRFYVATSRQLKRLESVSRSPIYSHFGETITGVQAIRAFREQDRFIKESEHRVDVNQVCYYPSIISNRWLAVRLEMIGNLIIFFAALFSVLGRDESQNAGLVGLSVTYSLQITQTLNWLVRMTSDVETNIVAVERIKEYGEAPQEAPWEIP-NKAPSPQWPENGTVQFNKYAVRYRPGLDLVLKGVNFSINGGEKVGIVGRTGAGKSSLTLALFRIIEAAEGEILIDGVNIADLGLHTLRSRLTIIPQDAVLFSGTLRMNLDPFDKHSDEEVWKALEHAHLKSFVKGLTAGLHHEVTEGGENLSVGQRQLICLSRALLRKTKVLILDEATAAVDLETDDLIQKTIRSEFKNCTVLTIAHRLNTIMDSDRVVVLDNGRIVEFDSPSNLLKQQQSIFYSMCKDAGL 1523
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|749744031|ref|XP_011154501.1| (PREDICTED: multidrug resistance-associated protein 1 isoform X6 [Harpegnathos saltator]) HSP 1 Score: 1234.94 bits (3194), Expect = 0.000e+0 Identity = 684/1546 (44.24%), Postives = 963/1546 (62.29%), Query Frame = 0
Query: 8 FCRDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTWTRGRASTVSSKYGPLFLAK--FTFTLVIL-VNLLGQFCYTSGH--VGGSDKLVPSELFHYPCLLVFVGLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVEEWVLLITYVPIILGLFIAHCWVDIDPRAAEDLSLE-----DKASCLSLLVFSWLDGLLWQGHKTPLKWKNL-PKSPRSMNVTDNVKAFTKQWRK--QAEDKL-------------VDFTSP-IRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHM-DSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVT------SEVETDELKVLATTT---KEPPKREVRVPSEEVESPEET-----------------------------DNLIEE--------TADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSD--RTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSR--ENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLP--LDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
FC F+D +L W T +P+VT C T+L+ VPCI I S + + Y ++ R + Y LF+ K T L+IL + LG Y S + V D P + ++ F+ ++L K+ G S LFLFW L +C + + I + + V + Y PI+L LF+ + VD +P+ +E ++E AS S L+F+W D L W+G + PL+ +L +P M + + V F K W K Q D++ VDF S + S+ P + K G L + L + ++ F+SPQ++++LI + + EP+W+G+FY ++L ++ L T+ Y + + +++R +L+ A+Y+K+LR+SN AR+ ++GE+ N MSVDAQR ++ Y+ + +PL I++A+YFL+ L A LAGL V I IP+N + VK LQ++Q+++KD R+KLMNE+L GIKVLKLYAWE F ++I +IR EI+++K L A +F + +P LV++ F YV +D +VL + FV+++LFN++R PL P + V+ +VS+KRIN+F+N ++D NV H ++ PHA+ + WD + PIL +N+ + G L A+VGTVG+GKSSLLS+ LGEM+KLSG+V +GSIAYV QQ WIQN TL+DN+LF + + + Y +VI C L PDL IL D+TEIGE GINLSGGQKQRV+LARAVY+D+D Y LDDPLSAVD+HVGK IF V+ G LK KTRVLVTH + +L ++DNIIVLK+G++ E G+Y++LL AF++FL+Q+ SE + E+K +T E ++ R S + ES E+ +N I+E T + LIE EK G V KVY Y+ SIG + + + +N WLS W+D N P D R YLGVYG +G+ Q + F +L + C A++ +H +L+ VMR+P+ FFDT P GRI++RF+ D+D +D +P +SD I+C F+ ++ + V+ STPIF +VI+P+G +Y+F+QRF+V S+Q+KR ESV++S I++HFSE++TG + IRAY Q++F+HES++RV C + ++ ANRWL +R+E++GNL++FFAA+FAVL R +++S GI GLS++YAL I TLNW++RM ++ETN VA+ERI EY EA W PK WP+ G V F+++ RYR GLDLVL GI V +EKIGI GRTGAGKSSLTL+LFRIIEA G ILID DI++LGLH LRS++TIIPQDPVLF+G LR NLDP + H+D E+W AL+HAHLK + +L L HE+SEGGEN SVGQRQLICLARALLRKTK+L+LDEATAAVDL TDDLIQ+TIR EF+ CTV+TIAHRLNTILD D++ V G I E+ SP LL NPTS+ +M DAGL
Sbjct: 9 FCGTEFWDANLTWYTNNPDVTVCFEKTILIWVPCIFLWIFSSMEAYYILHSKRR----NVPYTWLFIIKQVLTIALIILSIVDLGMAIYESTYREVYSVDYCTP-----FIKIITFILASILMIYNRKY-GMRTSGLLFLFWFILALCGCVQFRTFINKLIDREKSTYPIVSYMIYYPIVLLLFVLNFLVDAEPKFSEYPTVESPCPEQSASYPSRLLFAWFDALAWKGFRKPLEASDLWSMNPEDMAM-EIVPKFDKYWDKNLQKTDEVESAKASFRKASGQVDFNSGRKKKIASILPPICKAFGATFLFGAFLKLVQDIMTFISPQLLRVLIAFVKEKEEPLWKGYFYAVLLFLTATLQTLVLSQYFHRMFLVGLRIRTALIAAIYRKALRMSNAARKESTLGEIVNLMSVDAQRFMDLTAYINMIWSAPLQIVLALYFLWEILGPAVLAGLAVMIILIPVNALIANKVKTLQIRQMKSKDERVKLMNEVLNGIKVLKLYAWEPSFEQQILKIRAKEIQVLKEAAYLNAGTSFIWSCAPFLVSLVSFATYVLIDEKNVLNSSTAFVSLSLFNVLRFPLSMLPMMISNIVQAYVSVKRINKFMNMDDLDPNNVQHDPSE--PHALLIENGNFCWDMEHVDRPILQNINMHVEQGQLVAVVGTVGSGKSSLLSALLGEMDKLSGKVNTKGSIAYVSQQPWIQNATLQDNVLFGKALNKSVYNRVIEACALSPDLKILPAGDQTEIGEKGINLSGGQKQRVALARAVYNDSDNYFLDDPLSAVDSHVGKHIFENVI-GPGGLLKKKTRVLVTHGITYLPEVDNIIVLKDGEITECGTYKQLLEKRGAFADFLVQHLQEVGNLHVDDGSEADLREIKQQLESTMGADELQQKLTRARSRKSESLSESGSITDRRSLNGSLKRQYSTESQQSANYIHNNSIKEKEATKTNNTGEKLIEVEKAETGSVKWKVYSHYLVSIGLFLSVATIVMNAIFQAFSIGSNVWLSVWSDDNMTTPNGTIDKGRQDMYLGVYGALGIGQAMTSFFCDLAPQLGCWLAARQMHIVMLRAVMRAPLTFFDTTPIGRIISRFAKDVDVLDTSLPPQISDTIYCLFEVIATLFVISYSTPIFIAVILPIGALYYFIQRFYVASSRQLKRLESVSRSPIYSHFSESVTGASIIRAYGVQEQFIHESESRVDINQVCYYPSIIANRWLAVRLEMVGNLIIFFAALFAVLGRDSQDMSAGIVGLSVSYALQITQTLNWLVRMTSDVETNIVAVERIKEYGETTQEASWKNSEYTPPK---EWPSNGRVDFRNFKVRYREGLDLVLHGISFSVLGSEKIGIVGRTGAGKSSLTLALFRIIEAASGEILIDDIDISKLGLHDLRSKLTIIPQDPVLFSGTLRMNLDPFDNHTDDEVWRALEHAHLKSFVKNLPSSLLHEVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRHEFKDCTVLTIAHRLNTILDSDKVIVLDKGLIVEYDSPDTLLRNPTSSFYSMAKDAGL 1537
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|1126581818|ref|XP_019701148.1| (PREDICTED: multidrug resistance-associated protein 1 isoform X3 [Harpegnathos saltator]) HSP 1 Score: 1234.17 bits (3192), Expect = 0.000e+0 Identity = 685/1553 (44.11%), Postives = 963/1553 (62.01%), Query Frame = 0
Query: 8 FCRDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTWTRGRASTVSSKYGPLFLAK--FTFTLVIL-VNLLGQFCYTSGH--VGGSDKLVPSELFHYPCLLVFVGLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVEEWVLLITYVPIILGLFIAHCWVDIDPRAAEDLSLE-----DKASCLSLLVFSWLDGLLWQGHKTPLKWKNL-PKSPRSMNVTDNVKAFTKQWRK--QAEDKLV--------------------DFTSP-IRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHM-DSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVT------SEVETDELKVLATTT---KEPPKREVRVPSEEVESPEET-----------------------------DNLIEE--------TADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSD--RTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSR--ENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLP--LDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
FC F+D +L W T +P+VT C T+L+ VPCI I S + + Y ++ R + Y LF+ K T L+IL + LG Y S + V D P + ++ F+ ++L K+ G S LFLFW L +C + + I + + V + Y PI+L LF+ + VD +P+ +E ++E AS S L+F+W D L W+G + PL+ +L +P M + + V F K W K Q D+LV DF S + S+ P + K G L + L + ++ F+SPQ++++LI + + EP+W+G+FY ++L ++ L T+ Y + + +++R +L+ A+Y+K+LR+SN AR+ ++GE+ N MSVDAQR ++ Y+ + +PL I++A+YFL+ L A LAGL V I IP+N + VK LQ++Q+++KD R+KLMNE+L GIKVLKLYAWE F ++I +IR EI+++K L A +F + +P LV++ F YV +D +VL + FV+++LFN++R PL P + V+ +VS+KRIN+F+N ++D NV H ++ PHA+ + WD + PIL +N+ + G L A+VGTVG+GKSSLLS+ LGEM+KLSG+V +GSIAYV QQ WIQN TL+DN+LF + + + Y +VI C L PDL IL D+TEIGE GINLSGGQKQRV+LARAVY+D+D Y LDDPLSAVD+HVGK IF V+ G LK KTRVLVTH + +L ++DNIIVLK+G++ E G+Y++LL AF++FL+Q+ SE + E+K +T E ++ R S + ES E+ +N I+E T + LIE EK G V KVY Y+ SIG + + + +N WLS W+D N P D R YLGVYG +G+ Q + F +L + C A++ +H +L+ VMR+P+ FFDT P GRI++RF+ D+D +D +P +SD I+C F+ ++ + V+ STPIF +VI+P+G +Y+F+QRF+V S+Q+KR ESV++S I++HFSE++TG + IRAY Q++F+HES++RV C + ++ ANRWL +R+E++GNL++FFAA+FAVL R +++S GI GLS++YAL I TLNW++RM ++ETN VA+ERI EY EA W PK WP+ G V F+++ RYR GLDLVL GI V +EKIGI GRTGAGKSSLTL+LFRIIEA G ILID DI++LGLH LRS++TIIPQDPVLF+G LR NLDP + H+D E+W AL+HAHLK + +L L HE+SEGGEN SVGQRQLICLARALLRKTK+L+LDEATAAVDL TDDLIQ+TIR EF+ CTV+TIAHRLNTILD D++ V G I E+ SP LL NPTS+ +M DAGL
Sbjct: 9 FCGTEFWDANLTWYTNNPDVTVCFEKTILIWVPCIFLWIFSSMEAYYILHSKRR----NVPYTWLFIIKQVLTIALIILSIVDLGMAIYESTYREVYSVDYCTP-----FIKIITFILASILMIYNRKY-GMRTSGLLFLFWFILALCGCVQFRTFINKLIDREKSTYPIVSYMIYYPIVLLLFVLNFLVDAEPKFSEYPTVESPCPEQSASYPSRLLFAWFDALAWKGFRKPLEASDLWSMNPEDMAM-EIVPKFDKYWDKNLQKTDELVWTYLRVESAKASFRKASGQVDFNSGRKKKIASILPPICKAFGATFLFGAFLKLVQDIMTFISPQLLRVLIAFVKEKEEPLWKGYFYAVLLFLTATLQTLVLSQYFHRMFLVGLRIRTALIAAIYRKALRMSNAARKESTLGEIVNLMSVDAQRFMDLTAYINMIWSAPLQIVLALYFLWEILGPAVLAGLAVMIILIPVNALIANKVKTLQIRQMKSKDERVKLMNEVLNGIKVLKLYAWEPSFEQQILKIRAKEIQVLKEAAYLNAGTSFIWSCAPFLVSLVSFATYVLIDEKNVLNSSTAFVSLSLFNVLRFPLSMLPMMISNIVQAYVSVKRINKFMNMDDLDPNNVQHDPSE--PHALLIENGNFCWDMEHVDRPILQNINMHVEQGQLVAVVGTVGSGKSSLLSALLGEMDKLSGKVNTKGSIAYVSQQPWIQNATLQDNVLFGKALNKSVYNRVIEACALSPDLKILPAGDQTEIGEKGINLSGGQKQRVALARAVYNDSDNYFLDDPLSAVDSHVGKHIFENVI-GPGGLLKKKTRVLVTHGITYLPEVDNIIVLKDGEITECGTYKQLLEKRGAFADFLVQHLQEVGNLHVDDGSEADLREIKQQLESTMGADELQQKLTRARSRKSESLSESGSITDRRSLNGSLKRQYSTESQQSANYIHNNSIKEKEATKTNNTGEKLIEVEKAETGSVKWKVYSHYLVSIGLFLSVATIVMNAIFQAFSIGSNVWLSVWSDDNMTTPNGTIDKGRQDMYLGVYGALGIGQAMTSFFCDLAPQLGCWLAARQMHIVMLRAVMRAPLTFFDTTPIGRIISRFAKDVDVLDTSLPPQISDTIYCLFEVIATLFVISYSTPIFIAVILPIGALYYFIQRFYVASSRQLKRLESVSRSPIYSHFSESVTGASIIRAYGVQEQFIHESESRVDINQVCYYPSIIANRWLAVRLEMVGNLIIFFAALFAVLGRDSQDMSAGIVGLSVSYALQITQTLNWLVRMTSDVETNIVAVERIKEYGETTQEASWKNSEYTPPK---EWPSNGRVDFRNFKVRYREGLDLVLHGISFSVLGSEKIGIVGRTGAGKSSLTLALFRIIEAASGEILIDDIDISKLGLHDLRSKLTIIPQDPVLFSGTLRMNLDPFDNHTDDEVWRALEHAHLKSFVKNLPSSLLHEVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRHEFKDCTVLTIAHRLNTILDSDKVIVLDKGLIVEYDSPDTLLRNPTSSFYSMAKDAGL 1544
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|1080053910|ref|XP_018568575.1| (multidrug resistance-associated protein 1 isoform X6 [Anoplophora glabripennis]) HSP 1 Score: 1233.01 bits (3189), Expect = 0.000e+0 Identity = 680/1537 (44.24%), Postives = 958/1537 (62.33%), Query Frame = 0
Query: 8 FCRDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTWTRGRASTVSSKYGPLFLAKFTFTLVILVNLLGQFCYTSGHVGGSDKLVPSELFHYPCLLVFV-GLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDI---QSRMVASGTVEEWVLLITYVPIILGLFIAHCWVDIDPR-----AAEDLSLEDKASCLSLLVFSWLDGLLWQGHKTPLKWKNLPKSPRSMNVTDNVKAFTKQWR-----------------KQAEDKLVDFTSPIRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHMDSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVTSE--------VETDELK---VLATTTKEPPKREVRVPSEEVESPEE--TDNL------------------------IEETADD-----LIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHN--EAHPETGSDRTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSP-MAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSRENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLPLDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
FC F++L+L WNT DP+ T+C T+LV +PC S + Y ++ R + + L ++K T ++ + L + SD +V S + P + +F L+ L ++ G S LFLFWL L +C + + +I Q + G+ ++ + Y P++L +F+ +C+ D PR +E E+ AS LS L+F+W D L W G + PL+ +L + + V F K W+ K D + S + S+ P L K+ G ++ L + +L FVSPQI+ +I ++ + W+G+F+T +L ++ + T+ Y + I +++R +L+ +Y+KSL++SN AR+ +VGE+ N MSVDAQ+ +E ++ + +PL I++++YFL+ EL + LAGL V I IP+N F + VK LQ++Q++ KD R+KLMNE+L GIKVLKLYAWE F ++ +IR EIK++K L A +F + +P LV++ F +V +D +VL A+K +V+I+LFN++R P+ P + V+ +VS+KRIN F+N+ E+D NV H + + P IE + T +W G DPIL +N+ + +LTA+VGTVG+GKSSL+S+FLGEM+K+SG+V G IAYV QQAWIQN TL+DNILF ++F Y KVI C L+ D +L D+TEIGE GINLSGGQKQRVSLARAVYSDADIY LDDPLSAVD+HVGK IF +V+ +G L+ KT+VLVTH + +L + D+IIV+K+G+V+ESG+YQ+LL AF+EFL+Q+ + V ++ + DE+K V ++E +R R S ES E +D + IEE+ +D LIE EK G V VY Y++SIG F + L + +N WL WA+ + + + R YLGVYG +G+ Q+I+ F L + A++++H+ +L +MR P F+D P GRI+NRFS DID +D V+P L I C + + I V+ +TP+F VI+P+GL+Y+F+QRF+V S+Q+KR ESV++S I++HF ET+TG+ +IRAY QQ+RF+ ES+ +V C + +V +NRWL +R+E++GNL++ FA++FAVL +E P + GLSITYAL I TLNW++RM ++ETN VA+ERI EY EA W++P + WP G+V F +YA RYR GLDLVLKG+D ++ EK+GI GRTGAGKSSLTLSLFRIIEA +G+I IDG +IA+LGLHTLRSR+TIIPQD VLF+G LR NLDP + HSD E+W AL+HAHLK +S L L HE+SEGGEN SVGQRQLICLARALLRKTK+LVLDEATAAVDL TDDLIQ+TIR EF+ CTV+TIAHRLNTI+D DR+ V GQI EF +PA LLANP + M DAGL
Sbjct: 9 FCGGEFWNLNLTWNTNDPDFTKCFEKTVLVWIPCFFLWTFSSLEVYYLIKSKRR----NIPWNWLNISKLVVTGILSILCLSDLV-NAFKSADSDNVVYSVDIYSPLIKLFTFALSALLVVYNRKHGMPSSGLLFLFWLLLGVCGAVQFRSEIRRAQRSEIPPGSKYFYISYLIYYPLVLLMFLLNCFADKPPRESKYPKSERPCPEENASFLSRLLFTWFDSLAWTGFRKPLEATDLWDMKPEDSAKEIVPLFEKHWQNTLDKSGSYSPTQNAQFKSDVDHVAFVNSKKKKEASVLPALVKSFGPTFAFGALLKLMQDILTFVSPQILGYIITYVRKGQYEWRGYFFTALLFITATIQTLLLAQYFNRMFIVGMRIRTALISTIYRKSLKISNSARKETTVGEIVNLMSVDAQKFIELTAFLNMIWSAPLQIILSLYFLWYELGPSVLAGLAVMIILIPVNGFIANKVKTLQIKQMKNKDERVKLMNEILSGIKVLKLYAWEPSFENQVLKIRNKEIKVLKSAAYLNAGTSFIWSCAPFLVSLVTFATFVLVDENNVLDANKAYVSISLFNILRFPMSMLPMMISNLVQTYVSVKRINRFMNSEELDPNNVTHDSFEADPLIIE--KGTFSW----GDDPILKNINIRLKKQTLTAVVGTVGSGKSSLISAFLGEMDKVSGRVNTVGRIAYVSQQAWIQNATLKDNILFGKKFDKVLYNKVIEMCALKADFEMLPGGDQTEIGEKGINLSGGQKQRVSLARAVYSDADIYFLDDPLSAVDSHVGKHIFDKVI-GPKGMLRYKTKVLVTHGITYLPQTDSIIVIKDGEVSESGTYQELLDKKGAFAEFLLQHITEDVDTDDGLGKQIKTDLDEIKDQLVGTALSEEVTRRLSRHRSRVSESHSECGSDRILNGSLQRQKSSDSTDKSLRRRAGSIEESKNDSPKGKLIEIEKAETGSVSWDVYKHYLKSIGLFLTFATILLNMVFQGFSIGSNVWLGVWANDSSLNVNGTVNTARRDLYLGVYGALGIGQVIVIFLATLALFIGSLNAARLLHNVILSNIMRVPSTTFYDVTPVGRILNRFSKDIDTLDTVLPMTLRGWITCFYAVIGTIAVISYTTPLFMLVIVPIGLLYYFIQRFYVATSRQLKRLESVSRSPIYSHFGETVTGVQAIRAYGQQERFISESEYKVDLNQVCYYPSVISNRWLAVRLEMIGNLIILFASLFAVLGKEQ-DPSLVGLSITYALQITQTLNWLVRMTSDVETNIVAVERIKEYGEAPQEAPWEIP-NKNPSSAWPEHGSVEFNNYAVRYRPGLDLVLKGVDFHIKGGEKVGIVGRTGAGKSSLTLSLFRIIEAAQGQICIDGVNIAELGLHTLRSRLTIIPQDAVLFSGTLRMNLDPFDKHSDEEVWRALEHAHLKVFVSGLAAALNHEVSEGGENLSVGQRQLICLARALLRKTKVLVLDEATAAVDLETDDLIQTTIRTEFKTCTVLTIAHRLNTIMDSDRVIVLDKGQIVEFDTPANLLANPNTIFHGMCRDAGL 1531
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Match: gi|749744033|ref|XP_011154502.1| (PREDICTED: multidrug resistance-associated protein 1 isoform X7 [Harpegnathos saltator]) HSP 1 Score: 1232.62 bits (3188), Expect = 0.000e+0 Identity = 682/1543 (44.20%), Postives = 960/1543 (62.22%), Query Frame = 0
Query: 8 FCRDPFFDLDLVWNTTDPNVTQCMRDTLLVGVPCILFLIASLIWSIYQTWTRGRASTVSSKYGPLFLAK--FTFTLVIL-VNLLGQFCYTSGH--VGGSDKLVPSELFHYPCLLVFVGLALLQTAVDKFLGAHISPPLFLFWLALLICEIPKLKIDIQSRMVASGTVEEWVLLITYVPIILGLFIAHCWVDIDPRAAEDLSLE-----DKASCLSLLVFSWLDGLLWQGHKTPLKWKNL-PKSPRSMNVTDNVKAFTKQWRK--QAEDKL-------------VDFTSP-IRPFVSLWPILFKNHGWRALIALIVALFRVLLPFVSPQIIKLLIKHM-DSNEPVWQGFFYTIVLLFSSLLSTMAFHAYQQHLHISAIQMRNSLLGALYQKSLRLSNKARRLYSVGEMTNYMSVDAQRIVETFPYMMGLIMSPLTILIAMYFLFTELNVASLAGLVVFAIFIPINLFGSKCVKKLQVQQLQAKDTRLKLMNELLMGIKVLKLYAWEIPFMRRIYEIRLTEIKIIKMCGRLWAFINFSYCSSPILVTIGVFGIYVAMDPTHVLTADKIFVAIALFNLMRSPLVSFPFTLIESVKVFVSLKRINEFLNASEIDSTNVIHTANDLSPHAIEMTEATLTWDSDDGVDPILSQMNLSIPCGSLTAIVGTVGAGKSSLLSSFLGEMEKLSGQVQVRGSIAYVPQQAWIQNMTLRDNILFDQEFSSTNYTKVIRDCQLEPDLAILKHRDRTEIGENGINLSGGQKQRVSLARAVYSDADIYLLDDPLSAVDAHVGKAIFTQVLDSTEGCLKDKTRVLVTHNVNFLDKMDNIIVLKNGKVAESGSYQKLLADGKAFSEFLIQYTSNPVT---SEVETDELKVLATTT---KEPPKREVRVPSEEVESPEET-----------------------------DNLIEE--------TADDLIEEEKTVAGRVGAKVYWTYVQSIGTSQFFTVVFLYGLASVVHALANYWLSRWADHNEAHPETGSD--RTGFYLGVYGGIGVVQLILDFSRELLHIMSCAQASKVIHDKLLQGVMRSPMAFFDTNPTGRIVNRFSSDIDGVDQVVPAGLSDIIWCAFDTLSVIVVVCSSTPIFASVIIPLGLIYFFVQRFFVIPSQQIKRAESVTKSAIFAHFSETITGLASIRAYQQQDRFLHESQARVQKCTNCTFLNVSANRWLGLRVEVLGNLVVFFAAIFAVLSR--ENLSPGIAGLSITYALGIMDTLNWMIRMLCELETNSVALERILEYTHNESEAEWDLP--LDPKVGHTWPTEGAVSFKSYATRYRNGLDLVLKGIDMEVRSNEKIGICGRTGAGKSSLTLSLFRIIEAVKGRILIDGQDIAQLGLHTLRSRITIIPQDPVLFTGNLRFNLDPNEIHSDGEIWSALDHAHLKGHISDLKLGLYHEISEGGENFSVGQRQLICLARALLRKTKILVLDEATAAVDLVTDDLIQSTIRREFEHCTVITIAHRLNTILDCDRIAVFSHGQIAEFGSPAELLANPTSALKAMKNDAGL 1473
FC F+D +L W T +P+VT C T+L+ VPCI I S + + Y ++ R + Y LF+ K T L+IL + LG Y S + V D P + ++ F+ ++L K+ G S LFLFW L +C + + I + + V + Y PI+L LF+ + VD +P+ +E ++E AS S L+F+W D L W+G + PL+ +L +P M + + V F K W K Q D++ VDF S + S+ P + K G L + L + ++ F+SPQ++++LI + + EP+W+G+FY ++L ++ L T+ Y + + +++R +L+ A+Y+K+LR+SN AR+ ++GE+ N MSVDAQR ++ Y+ + +PL I++A+YFL+ L A LAGL V I IP+N + VK LQ++Q+++KD R+KLMNE+L GIKVLKLYAWE F ++I +IR EI+++K L A +F + +P LV++ F YV +D +VL + FV+++LFN++R PL P + V+ +VS+KRIN+F+N ++D NV H ++ PHA+ + WD + PIL +N+ + G L A+VGTVG+GKSSLLS+ LGEM+KLSG+V +GSIAYV QQ WIQN TL+DN+LF + + + Y +VI C L PDL IL D+TEIGE GINLSGGQKQRV+LARAVY+D+D Y LDDPLSAVD+HVGK IF V+ G LK KTRVLVTH + +L ++DNIIVLK+G++ E G+Y++LL AF++FL+Q+ SE + E+K +T E ++ R S + ES E+ +N I+E T + LIE EK G V KVY Y+ SIG + + + +N WLS W+D N P D R YLGVYG +G+ Q + ++ C Q+SK++H +LL G++RSP+ FFD P+GRI+NRF D+D +D V+P + ++C ++ + V+ STPIF +VI+P+G +Y+F+QRF+V S+Q+KR ESV++S I++HFSE++TG + IRAY Q++F+HES++RV C + ++ ANRWL +R+E++GNL++FFAA+FAVL R +++S GI GLS++YAL I TLNW++RM ++ETN VA+ERI EY EA W PK WP+ G V F+++ RYR GLDLVL GI V +EKIGI GRTGAGKSSLTL+LFRIIEA G ILID DI++LGLH LRS++TIIPQDPVLF+G LR NLDP + H+D E+W AL+HAHLK + +L L HE+SEGGEN SVGQRQLICLARALLRKTK+L+LDEATAAVDL TDDLIQ+TIR EF+ CTV+TIAHRLNTILD D++ V G I E+ SP LL NPTS+ +M DAGL
Sbjct: 9 FCGTEFWDANLTWYTNNPDVTVCFEKTILIWVPCIFLWIFSSMEAYYILHSKRR----NVPYTWLFIIKQVLTIALIILSIVDLGMAIYESTYREVYSVDYCTP-----FIKIITFILASILMIYNRKY-GMRTSGLLFLFWFILALCGCVQFRTFINKLIDREKSTYPIVSYMIYYPIVLLLFVLNFLVDAEPKFSEYPTVESPCPEQSASYPSRLLFAWFDALAWKGFRKPLEASDLWSMNPEDMAM-EIVPKFDKYWDKNLQKTDEVESAKASFRKASGQVDFNSGRKKKIASILPPICKAFGATFLFGAFLKLVQDIMTFISPQLLRVLIAFVKEKEEPLWKGYFYAVLLFLTATLQTLVLSQYFHRMFLVGLRIRTALIAAIYRKALRMSNAARKESTLGEIVNLMSVDAQRFMDLTAYINMIWSAPLQIVLALYFLWEILGPAVLAGLAVMIILIPVNALIANKVKTLQIRQMKSKDERVKLMNEVLNGIKVLKLYAWEPSFEQQILKIRAKEIQVLKEAAYLNAGTSFIWSCAPFLVSLVSFATYVLIDEKNVLNSSTAFVSLSLFNVLRFPLSMLPMMISNIVQAYVSVKRINKFMNMDDLDPNNVQHDPSE--PHALLIENGNFCWDMEHVDRPILQNINMHVEQGQLVAVVGTVGSGKSSLLSALLGEMDKLSGKVNTKGSIAYVSQQPWIQNATLQDNVLFGKALNKSVYNRVIEACALSPDLKILPAGDQTEIGEKGINLSGGQKQRVALARAVYNDSDNYFLDDPLSAVDSHVGKHIFENVI-GPGGLLKKKTRVLVTHGITYLPEVDNIIVLKDGEITECGTYKQLLEKRGAFADFLVQHLQEVHVDDGSEADLREIKQQLESTMGADELQQKLTRARSRKSESLSESGSITDRRSLNGSLKRQYSTESQQSANYIHNNSIKEKEATKTNNTGEKLIEVEKAETGSVKWKVYSHYLVSIGLFLSVATIVMNAIFQAFSIGSNVWLSVWSDDNMTTPNGTIDKGRQDMYLGVYGALGIGQATFVMLSQTALVVGCLQSSKLLHSELLFGILRSPLGFFDITPSGRILNRFGKDVDVIDNVLPPCIRAWLFCLTSVIATLFVISYSTPIFIAVILPIGALYYFIQRFYVASSRQLKRLESVSRSPIYSHFSESVTGASIIRAYGVQEQFIHESESRVDINQVCYYPSIIANRWLAVRLEMVGNLIIFFAALFAVLGRDSQDMSAGIVGLSVSYALQITQTLNWLVRMTSDVETNIVAVERIKEYGETTQEASWKNSEYTPPK---EWPSNGRVDFRNFKVRYREGLDLVLHGISFSVLGSEKIGIVGRTGAGKSSLTLALFRIIEAASGEILIDDIDISKLGLHDLRSKLTIIPQDPVLFSGTLRMNLDPFDNHTDDEVWRALEHAHLKSFVKNLPSSLLHEVSEGGENLSVGQRQLICLARALLRKTKVLILDEATAAVDLETDDLIQTTIRHEFKDCTVLTIAHRLNTILDSDKVIVLDKGLIVEYDSPDTLLRNPTSSFYSMAKDAGL 1534 The following BLAST results are available for this feature:
BLAST of multidrug resistance-associated protein 1 isoform x3 vs. L. salmonis genes
Analysis Date: 2018-04-19 (T. kinsejongensis vs L. Salmonis peptides) Total hits: 19
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BLAST of multidrug resistance-associated protein 1 isoform x3 vs. SwissProt
Analysis Date: 2018-04-19 (T. kingejongensis peptided Blastp vs. SwissProt) Total hits: 25
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BLAST of multidrug resistance-associated protein 1 isoform x3 vs. nr
Analysis Date: 2018-05-15 (T. kingsejongensis proteins Blastp vs. NR) Total hits: 25
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The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at scaffold1304_size49437:19244..23665- Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>snap_masked-scaffold1304_size49437-processed-gene-0.4 ID=snap_masked-scaffold1304_size49437-processed-gene-0.4|Name=multidrug resistance-associated protein 1 isoform x3|organism=Tigriopus kingsejongensis|type=gene|length=4422bp|location=Sequence derived from alignment at scaffold1304_size49437:19244..23665- (Tigriopus kingsejongensis)back to top Synonyms
The feature 'multidrug resistance-associated protein 1 isoform x3' has the following synonyms
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