3-hydroxy-3-methylglutaryl- reductase, snap_masked-scaffold208_size258758-processed-gene-1.0 (gene) Tigriopus kingsejongensis

Overview


Name	3-hydroxy-3-methylglutaryl- reductase
Unique Name	snap_masked-scaffold208_size258758-processed-gene-1.0
Type	gene
Organism	Tigriopus kingsejongensis (Tigriopus kingsejongensis)

Associated RNAi Experiments

Nothing found

Homology

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BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. L. salmonis genes
Match: EMLSAG00000004979 (supercontig:LSalAtl2s:LSalAtl2s260:1508384:1510927:-1 gene:EMLSAG00000004979 transcript:EMLSAT00000004979 description:"augustus_masked-LSalAtl2s260-processed-gene-14.5")

HSP 1 Score: 749.969 bits (1935), Expect = 0.000e+0
Identity = 427/915 (46.67%), Postives = 576/915 (62.95%), Query Frame = 0

Query:   34 RSLPTLFIRKIFKSHGEFCASQPWEVIVTTFIFLICVLTVGSKHVMMVTEMDSSASSKIKPCLPSDPSCVPEHHSRDWIETLVMAGFYCLAVLHITYRFKKIHLIRSNLIFNIALCYMTFASLLYALIIWSIGNPLKDNLHQAWFLIFLLVDMQKVTRMGQFALSSSHHRRISENVANGMYVLAPTFALDCLAKIFLVGLGSLTRIPQLEAFSWYAVVSVMVNFLVYLTFYPAGLSLVLELMYCTDGRPRWDVRQIINTLPGED--GQTPVVHRVKVVATALLMIAHII-FRPPFLFSSASGISQPTTTLFSWATTNIEKVLITVVIVALSIKYLFYEDMDE---AQELRKTYIEELTRKFAEDSEQEEFNRGNKVEMDRVSNSTDEGISIGSSAKPRPPSCASR---HGDDSSSESAWSEVGYLPDLKDQEAQTTD---MASSEDEVDDDENGEKRRIRH-----HHQLPKEPRSLEECTKIYKGTMDGVEY--LIDEEVVHLVEKKVIRAHALESVLNNPTRGVEIRRKYV---EKVAKRDIGNLPFRNFDYDTVMGACCESVIGYMTMPVGVAGPLNLDGQLFYVPMATTEGCLVASVNRGCSALRTCG-VTSRILADGMTRGPIVRFPNIAKMAEAKEWMEEPENFLQIKSNFDSTSRFARLQRLKLKPAGRELYIRFVAYTGDAMGMNMISKAAEFSLKQLIDVFPEMELVSLSGNMCTDKKPAAINWLDGRGKSVICEATVPGHIVETVLKTSPAALADLNRSKNLVGSAMAGSIGGFNAQAANVVTAVFIATGQDAAQNVASSNCLTQIDVV---GDDLYMTCTMPSIEVGTVGGGTILTAQGACLDLLGVKGCQPASPGANAKQLASVVCATVLAGELSLMSALAAGHLVKSHLRHNRSNLAVGSVA 922
            R  P  F+  +    G+    QPWEV+  +   L+ ++T                       +P D        S +W   +V   F  L++L +  + K+IH + S ++ ++A  Y    + L ++  + +G P       A F + LL D+ K+T++ Q+ALS++H   + + ++  M  L PT   D L K+             L       V ++++   V+   YP  LS+ L L+    G+ +W+V++I+ TLP ++   +TP+    +V+A  +L++ H+   +PP L                    N   ++I++ +V LS  Y FY + DE   +  LRK+Y E  TRK     +Q+      K ++DR S STDEGI +  SA        S+    GDDSSSESAWSEV Y+PDLKDQEAQTT+   + SS DE  D+   E     H     HH     PRS+E C  I K      E   L DEEVV LVE++ IR+HALE VLN+  RGV +RRK +   E+  ++    LP+++FDY TVMGACCESV+GYM +PVG+ GPL LD +L+++PMATTEGCLVAS NRGCSAL  CG VTS+I  DGM+RGP+VRFPN++   +AK+W+E+P N+ +IK +FDSTSRFARL +LK++ AGR +Y+RFVA TGDAMGMNM+SKA EF+L +L  +FPEM+++S+SGNMCTDKKPAA+NW++GRGKSV+CEA VP  IVET+LKTS AAL DLN +KN  GSAMAGSIGGFNA +AN+VTA+FIATGQDAAQN+ SSNC+T ++     G DLY+TCTMPSIEVGT+GGGTIL  QG+CL++LGVKG  P SPG N++QLA ++C  VLAGELSLMSALAAG LV SHLRHNRS LAVG +A
Sbjct:    3 RRPPLKFLEDVSDCLGQATVKQPWEVLFVSLTSLLSLVTF----------------------VPLDGG------SPEWSPVVVFV-FRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY----AFLLSMTAFLLGGP------DAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKL--------LLFTLLPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLITSPQGQAKWNVKRILETLPTQEPPSRTPL----RVLAFPVLVLLHLTCLQPPSL---------------QLHIQNTPHIIISLSLVLLS--YYFYSNKDEDATSLHLRKSYEEAFTRKL---QDQDSSVSRLKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEV-YMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHS---PPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAVGKLA 842

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BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. SwissProt
Match: gi|391359371|sp|A7Z064.2|HMDH_BOVIN (RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase; Short=HMG-CoA reductase)

HSP 1 Score: 688.723 bits (1776), Expect = 0.000e+0
Identity = 387/936 (41.35%), Postives = 555/936 (59.29%), Query Frame = 0

Query:   40 FIRKIFKSHGEFCASQPWEVIVTTFIFLICVLTVGSKHVMMVTEMDSSASSKIKPCLPSDPSCVPEHHSRDWIETLVMAGFYCLAVLHITYRFKKIHLIRSNLIFNIALCYMTFASLLYALIIWSIGNPLKDNLHQAWFLIFLLVDMQKVTRMGQFALSSSHHRRISENVANGMYVLAPTFALDCLAKIFLVGLGSLTRIPQLEAFSWYAVVSVMVNFLVYLTFYPAGLSLVLELMY-CTDGRPRWDVRQIINTLPGEDGQ-TPVVHRVKVVATALLMIAHIIFR------PPFLFSSASGIS-----------QPTTTLFSW-----ATTNIEKVLITVVIVALSIKYLFYEDMDEAQEL------------RKTYIEELTR----------KFAEDSEQEEFNRGNKVEMDRVSNSTDEGISIGSSAKPRPPSCASRHGDDSSSESAWSEVGYLPDLKDQEAQTTDMASSEDEVDDDENGEKRRIRHHHQLPKEPRSLEECTKIYKGTMDGVEYLIDEEVVHLVEKKVIRAHALESVLNNPTRGVEIRRKYVEKVAKR--DIGNLPFRNFDYDTVMGACCESVIGYMTMPVGVAGPLNLDGQLFYVPMATTEGCLVASVNRGCSALRTCG-VTSRILADGMTRGPIVRFPNIAKMAEAKEWMEEPENFLQIKSNFDSTSRFARLQRLKLKPAGRELYIRFVAYTGDAMGMNMISKAAEFSLKQLIDVFPEMELVSLSGNMCTDKKPAAINWLDGRGKSVICEATVPGHIVETVLKTSPAALADLNRSKNLVGSAMAGSIGGFNAQAANVVTAVFIATGQDAAQNVASSNCLTQIDVVG---DDLYMTCTMPSIEVGTVGGGTILTAQGACLDLLGVKGCQPASPGANAKQLASVVCATVLAGELSLMSALAAGHLVKSHLRHNRSNLAVGSVAG 923
             + ++F+ HG F AS PWEVIV T    IC++++      M T      ++KI       P    +  S D I   ++    C+A+L+I ++F+ +  + S  I  IA  +  F+S +++ ++    +     L++A     LLVD+ + + + +FALSS+    + EN+A GM +L PTF LD L +  ++G+G+++ + QLE    +  +SV+ N+ V++TF+PA +SLVLEL     +GRP W +      L  E+ +  PV  RVK++ +  L++ H   R      P    +  S +S           +P+ +L+ +      + +IE+V+   + + L++KY+F+E  +    L            +K   ++  R          KF    E+   NR  KVE+ +                   P  A    ++ +S  A   VG            + +  +  E++  E           +LP EPR  EEC +I +    G ++L D E++ LV  K I A+ LE+++    RGV IRR+ + K       +  LP+R+++Y  VMGACCE+VIGYM +PVGVAGPL LDG+ F VPMATTEGCLVAS NRGC A+   G  +SR+LADGMTRGP+VRFP     AE K W+E PE F  IK  FDSTSRFARLQ+L +  AGR LYIRF + +GDAMGMNMISK  E +L +L + FPEM+++++SGN CTDKKPAAINW++GRGKSV+CEA +P  +V  VLKT+  A+ ++N +KNLVGSAMAGSIGG+NA AAN+VTA++IA GQDAAQNV SSNC+T ++  G   +DLY++CTMPSIE+GTVGGGT L  Q ACL +LGV+G    +PG NA+QLA +VC TV+AGELSLM+ALAAGHLV+SH+ HNRS + +  + G
Sbjct:    1 MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMN-----MFT-----GNNKICGWNYECPKLEEDVLSSDII---ILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLVDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADNSKVSLGLDENVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTQKKITDDCCRRDPVLVRNDQKFHAMEEETRKNRERKVEVIK-------------------PLLA----ENDTSHRATFVVG-----------NSSLLGTSLELETQE--------PEMELPVEPRPNEECLQILENAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSKKLPEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRFPRACDSAEVKAWLETPEGFTVIKEAFDSTSRFARLQKLHMSVAGRNLYIRFQSRSGDAMGMNMISKGTEKALSKLQEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREVLKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACRDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMIHNRSKINLQDLQG 881

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BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. SwissProt
Match: gi|2495262|sp|Q29512.1|HMDH_RABIT (RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase; Short=HMG-CoA reductase)

HSP 1 Score: 686.411 bits (1770), Expect = 0.000e+0
Identity = 391/923 (42.36%), Postives = 554/923 (60.02%), Query Frame = 0

Query:   40 FIRKIFKSHGEFCASQPWEVIVTTFIFLICVLTVGSKHVMMVTEMDSSASSKIKPCLPSDPSCVPEHHSRDWIETLVMAGFYCLAVLHITYRFKKIHLIRSNLIFNIALCYMTFASLLYALIIWSIGNPLKDNLHQAWFLIFLLVDMQKVTRMGQFALSSSHHRRISENVANGMYVLAPTFALDCLAKIFLVGLGSLTRIPQLEAFSWYAVVSVMVNFLVYLTFYPAGLSLVLELMY-CTDGRPRWDVRQIINTLPGEDGQ-TPVVHRVKVVATALLMIAHIIFR------PPFLFSSASGIS-----------QPTTTLFSW-----ATTNIEKVLITVVIVALSIKYLFYEDMDEAQELR-KTYIEE--LTRKFAEDS---EQEEFNRGNKVEMDRVSNSTDEGISIGSSAKPRPPSCASRHGDDSSSESAWSEVGY-LPDLKDQEAQTTDMASSEDEVDDDENGEKRRIRHHHQLPKEPRSLEECTKIYKGTMDGVEYLIDEEVVHLVEKKVIRAHALESVLNNPTRGVEIRRKYVEKVAKR--DIGNLPFRNFDYDTVMGACCESVIGYMTMPVGVAGPLNLDGQLFYVPMATTEGCLVASVNRGCSALRTC---GVTSRILADGMTRGPIVRFPNIAKMAEAKEWMEEPENFLQIKSNFDSTSRFARLQRLKLKPAGRELYIRFVAYTGDAMGMNMISKAAEFSLKQLIDVFPEMELVSLSGNMCTDKKPAAINWLDGRGKSVICEATVPGHIVETVLKTSPAALADLNRSKNLVGSAMAGSIGGFNAQAANVVTAVFIATGQDAAQNVASSNCLTQIDVVG---DDLYMTCTMPSIEVGTVGGGTILTAQGACLDLLGVKGCQPASPGANAKQLASVVCATVLAGELSLMSALAAGHLVKSHLRHNRSNLAVGSVAG 923
             + ++F+ HG F AS PWEVIV T    IC++++      M T  D     KI       P    +  S D I   ++    C+A+L+I ++F+ +  + S  I  IA  +  F+S +++ ++    +     L++A     LL+D+ + + + +FALSS+    + EN+A GM +L PTF LD L +  ++G+G+++ + QLE    +  +SV+ N+ V++TF+PA +SLVLEL     +GRP W +      L  E+ +  PV  RVK++ +  L++ H   R      P    +  S +S           +P+ +L+ +      + +IE+V+   + + L++KY+F+E  +    L  K  I    +T+K   DS    +    R N+      S   + G+S     +   P  A     DS   +A+   G   PD       +  + + E E++               LPKEPR  EEC +I      G ++L D E++ LV  K I A+ LE+++    RGV IRR+ + K       +  LP+R+++Y  V+GACCE+VIGYM +PVGV GPL LDG+ F VPMATTEGCLVAS NRGC A+  C   G +SR+LADGMTRGP+VR P     AE K W+E PE F  IK  FDSTSRFARLQ+L +  AGR LYIRF + TGDAMGMNMISK  E +L +L + FPEM+++++SGN CTDKKPAA+NW++GRGK+V+CEA +P  +V  VLKT+  A+ D+N +KNLVGSAMAGSIGG+NA AAN VTA++IA GQDAAQNV SSNC+T ++  G   +DLY++CTMPSIE+GTVGGGT L  Q ACL +LGV+G    SPG NA+QLA +VC TV+AGELSLM+ALAAGHLVKSH+ HNRS + +  + G
Sbjct:    1 MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMN-----MFTGND-----KICGWNYECPKFEEDVLSSDII---ILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADNSKVSLGLDENVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTQKKVPDSCCRREPVVVRNNQ---KFCSVEEEAGMSQDRKVEVIKPLVAE---TDSPHRAAFVVGGSSFPD------TSLVLETKEPEIE---------------LPKEPRPNEECLQILGNAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSKKLPEPSSLQYLPYRDYNYSLVLGACCENVIGYMPIPVGVVGPLCLDGKEFQVPMATTEGCLVASTNRGCRAI--CLGGGASSRVLADGMTRGPVVRLPRACDSAEVKAWLETPEGFAVIKEAFDSTSRFARLQKLHISMAGRNLYIRFQSRTGDAMGMNMISKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAVNWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMIDVNINKNLVGSAMAGSIGGYNAHAANYVTAIYIACGQDAAQNVGSSNCITLMEASGPPNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDSPGENARQLARIVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDLEG 881

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BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. SwissProt
Match: gi|118573790|sp|Q1W675.1|HMDH_PIG (RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase; Short=HMG-CoA reductase)

HSP 1 Score: 682.559 bits (1760), Expect = 0.000e+0
Identity = 388/937 (41.41%), Postives = 550/937 (58.70%), Query Frame = 0

Query:   40 FIRKIFKSHGEFCASQPWEVIVTTFIFLICVLTVGSKHVMMVTEMDSSASSKIKPCLPSDPSCVPEHHSRDWIETLVMAGFYCLAVLHITYRFKKIHLIRSNLIFNIALCYMTFASLLYALIIWSIGNPLKDNLHQAWFLIFLLVDMQKVTRMGQFALSSSHHRRISENVANGMYVLAPTFALDCLAKIFLVGLGSLTRIPQLEAFSWYAVVSVMVNFLVYLTFYPAGLSLVLELMY-CTDGRPRWDVRQIINTLPGEDGQ-TPVVHRVKVVATALLMIAHIIFR------PPFLFSSASGIS-----------QPTTTLFSW-----ATTNIEKVLITVVIVALSIKYLFYEDMDEAQEL------------RKTYIEELTR----------KFAEDSEQEEFNRGNKVEMDR-VSNSTDEGISIGSSAKPRPPSCASRHGDDSSSESAWSEVGYLPDLKDQEAQTTDMASSEDEVDDDENGEKRRIRHHHQLPKEPRSLEECTKIYKGTMDGVEYLIDEEVVHLVEKKVIRAHALESVLNNPTRGVEIRRKYVEKVAKR--DIGNLPFRNFDYDTVMGACCESVIGYMTMPVGVAGPLNLDGQLFYVPMATTEGCLVASVNRGCSALRTCG-VTSRILADGMTRGPIVRFPNIAKMAEAKEWMEEPENFLQIKSNFDSTSRFARLQRLKLKPAGRELYIRFVAYTGDAMGMNMISKAAEFSLKQLIDVFPEMELVSLSGNMCTDKKPAAINWLDGRGKSVICEATVPGHIVETVLKTSPAALADLNRSKNLVGSAMAGSIGGFNAQAANVVTAVFIATGQDAAQNVASSNCLTQIDVVG---DDLYMTCTMPSIEVGTVGGGTILTAQGACLDLLGVKGCQPASPGANAKQLASVVCATVLAGELSLMSALAAGHLVKSHLRHNRSNLAVGSVAG 923
             + ++F+ HG F AS PWEVIV T    IC++++      M T  D     KI       P    +  S D I   ++    C+A+L+I ++F+ +  + S  I  IA  +  F+S +++ ++    +     L++A     LL+D+ + + + +FALSS+    + EN+A GM +L PTF LD L +  ++G+G+++ + QLE    +  +SV+  + V++TF+PA +SLVLEL     +GRP W +      L GE+ +  PV  RVK++ +  L++ H   R      P    +  S +S           +P+ +L+ +      + +IE+V+   + + L++KY+F+E  +    L            +K   ++  R          KF    E+   NR  KVE+ + +   TD           RP         DSS E           L+ QE +                          Q+P EPR  EEC +I      G ++L D E++ LV  K I A+ LE+++    RGV IRR+ + K       +  LP+R+++Y  VMGACCE+VIGYM +PVGVAGPL LDG+ F VPMATTEGCLVAS NRGC A+   G  +SRILADGMT  P+VRFP     AE K W+E PE F  IK  FDSTSRFARLQ+L++  AGR LYIRF + +GDAMGMNMISK  E +L +L + FPEM+++++SGN CTDKKPAA+NW++GRGKSV+CEA +P  +V  VLKT+  A+ ++N +KNLVGSAMAGSIGG+NA AAN+VTA++IA GQDAAQNV SSNC+T ++  G   +DLY++CTMPSIE+GTVGGGT L  Q ACL +LGV+G    +PG NA+QLA +VC TV+AGELSLM+ALAAGHLV+SH+ HNRS + +  + G
Sbjct:    1 MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMN-----MFTGND-----KICGWNYECPKFEEDVLSSDII---ILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLATYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEGEENKPNPVTQRVKIIMSLGLVLVHAHSRWIADPSPQNSTADNSKVSLGLDENVSKRIEPSVSLWQFYLSKMISMDIEQVITLTLALLLAVKYIFFEQAETESTLSLKNPITSPVVTQKKVTDDCCRREPTLVRNDQKFHTVEEEARINRERKVEVIKPLVAETD--------TSSRPTFVVGNSTLDSSLE-----------LEMQEPEI-------------------------QIPSEPRPNEECLQILGNAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSKKLPEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRILADGMT--PVVRFPRACDSAEVKAWLETPEGFAVIKEAFDSTSRFARLQKLQMSVAGRNLYIRFQSRSGDAMGMNMISKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAVNWIEGRGKSVVCEAVIPAKVVREVLKTTTEAMVEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTSLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMIHNRSKINLQDLQG 878

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BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. SwissProt
Match: gi|123343|sp|P04035.1|HMDH_HUMAN (RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase; Short=HMG-CoA reductase)

HSP 1 Score: 681.404 bits (1757), Expect = 0.000e+0
Identity = 387/919 (42.11%), Postives = 554/919 (60.28%), Query Frame = 0

Query:   40 FIRKIFKSHGEFCASQPWEVIVTTFIFLICVLTVGSKHVMMVTEMDSSASSKIKPCLPSDPSCVPEHHSRDWIETLVMAGFYCLAVLHITYRFKKIHLIRSNLIFNIALCYMTFASLLYALIIWSIGNPLKDNLHQAWFLIFLLVDMQKVTRMGQFALSSSHHRRISENVANGMYVLAPTFALDCLAKIFLVGLGSLTRIPQLEAFSWYAVVSVMVNFLVYLTFYPAGLSLVLELMY-CTDGRPRWDVRQIINTLPGEDGQ-TPVVHRVKVVATALLMIAHIIFR------PPFLFSSASGIS-----------QPTTTLFSW-----ATTNIEKVLITVVIVALSIKYLFYEDMDEAQELR-KTYIEE--LTRKFAEDS--EQEEFNRGNKVEMDRVSNSTDEGISIGSSAKPRPPSCASRHGDDSSSESAWSEVGYLPDLKDQEAQTTDMASSEDEVDDDENGEKRRIRHHHQLPKEPRSLEECTKIYKGTMDGVEYLIDEEVVHLVEKKVIRAHALESVLNNPTRGVEIRRKYVEKVAKR--DIGNLPFRNFDYDTVMGACCESVIGYMTMPVGVAGPLNLDGQLFYVPMATTEGCLVASVNRGCSALRTCG-VTSRILADGMTRGPIVRFPNIAKMAEAKEWMEEPENFLQIKSNFDSTSRFARLQRLKLKPAGRELYIRFVAYTGDAMGMNMISKAAEFSLKQLIDVFPEMELVSLSGNMCTDKKPAAINWLDGRGKSVICEATVPGHIVETVLKTSPAALADLNRSKNLVGSAMAGSIGGFNAQAANVVTAVFIATGQDAAQNVASSNCLTQIDVVG---DDLYMTCTMPSIEVGTVGGGTILTAQGACLDLLGVKGCQPASPGANAKQLASVVCATVLAGELSLMSALAAGHLVKSHLRHNRSNLAVGSVAG 923
             + ++F+ HG F AS PWEVIV T    IC++++      M T      ++KI       P    +  S D I   ++    C+A+L+I ++F+ +  + S  I  IA  +  F+S +++ ++    +     L++A     LL+D+ + + + +FALSS+    + EN+A GM +L PTF LD L +  ++G+G+++ + QLE    +  +SV+ N+ V++TF+PA +SLVLEL     +GRP W +      L  E+ +  PV  RVK++ +  L++ H   R      P    +  S +S           +P+ +L+ +      + +IE+V+   + + L++KY+F+E  +    L  K  I    +T+K   D+   +E     N  + D V   T  GI+     +   P  A    +  +   A   VG    L D    ++ + + E E++               LP+EPR  EEC +I      G ++L D E++ LV  K I A+ LE+++    RGV IRR+ + K       +  LP+R+++Y  VMGACCE+VIGYM +PVGVAGPL LD + F VPMATTEGCLVAS NRGC A+   G  +SR+LADGMTRGP+VR P     AE K W+E  E F  IK  FDSTSRFARLQ+L    AGR LYIRF + +GDAMGMNMISK  E +L +L + FPEM+++++SGN CTDKKPAAINW++GRGKSV+CEA +P  +V  VLKT+  A+ ++N +KNLVGSAMAGSIGG+NA AAN+VTA++IA GQDAAQNV SSNC+T ++  G   +DLY++CTMPSIE+GTVGGGT L  Q ACL +LGV+G    +PG NA+QLA +VC TV+AGELSLM+ALAAGHLVKSH+ HNRS + +  + G
Sbjct:    1 MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMN-----MFT-----GNNKICGWNYECPKFEEDVLSSDII---ILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSLKNPITSPVVTQKKVPDNCCRREPMLVRNNQKCDSVEEET--GINRERKVEVIKPLVA----ETDTPNRATFVVGN-SSLLDT---SSVLVTQEPEIE---------------LPREPRPNEECLQILGNAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSKKLSEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDEKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRACDSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSRSGDAMGMNMISKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREVLKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDLQG 881

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BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. SwissProt
Match: gi|123344|sp|P09610.1|HMDH_MESAU (RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase; Short=HMG-CoA reductase)

HSP 1 Score: 681.019 bits (1756), Expect = 0.000e+0
Identity = 382/921 (41.48%), Postives = 554/921 (60.15%), Query Frame = 0

Query:   40 FIRKIFKSHGEFCASQPWEVIVTTFIFLICVLTVGSKHVMMVTEMDSSASSKIKPCLPSDPSCVPEHHSRDWIETLVMAGFYCLAVLHITYRFKKIHLIRSNLIFNIALCYMTFASLLYALIIWSIGNPLKDNLHQAWFLIFLLVDMQKVTRMGQFALSSSHHRRISENVANGMYVLAPTFALDCLAKIFLVGLGSLTRIPQLEAFSWYAVVSVMVNFLVYLTFYPAGLSLVLELMY-CTDGRPRWDVRQIINTLPGEDGQ-TPVVHRVKVVATALLMIAHIIFR------PPFLFSSASGIS-----------QPTTTLFSW-----ATTNIEKVLITVVIVALSIKYLFYEDMDEAQELR-KTYIEE--LTRKFAEDS---EQEEFNRGNKVEMDRVSNSTDE-GISIGSSAKPRPPSCASRHGDDSSSESAWSEVGYLPDLKDQEAQTTDMASSEDEVDDDENGEKRRIRHHHQLPKEPRSLEECTKIYKGTMDGVEYLIDEEVVHLVEKKVIRAHALESVLNNPTRGVEIRRKYVEKVAKR--DIGNLPFRNFDYDTVMGACCESVIGYMTMPVGVAGPLNLDGQLFYVPMATTEGCLVASVNRGCSALRTCG-VTSRILADGMTRGPIVRFPNIAKMAEAKEWMEEPENFLQIKSNFDSTSRFARLQRLKLKPAGRELYIRFVAYTGDAMGMNMISKAAEFSLKQLIDVFPEMELVSLSGNMCTDKKPAAINWLDGRGKSVICEATVPGHIVETVLKTSPAALADLNRSKNLVGSAMAGSIGGFNAQAANVVTAVFIATGQDAAQNVASSNCLTQIDVVG---DDLYMTCTMPSIEVGTVGGGTILTAQGACLDLLGVKGCQPASPGANAKQLASVVCATVLAGELSLMSALAAGHLVKSHLRHNRSNLAVGSVAG 923
             + ++F+ HG F AS PWEVIV T    IC++++      M T      ++KI       P    +  S D I   ++    C+A+L+I ++F+ +  + S  I  IA  +  F+S +++ ++    +     L++A     LL+D+ + + + +FALSS+    + EN+A GM +L PTF LD L +  ++G+G+++ + QLE    +  +SV+ N+ V++TF+PA +SLVLEL     +GRP W +      L  E+ +  PV  RVK++ +  L++ H   R      P    +  S +S           +P+ +L+ +      + +IE+V+   +   L++KY+F+E  +    L  K  I     T K A D+    +   +R N    +++S+  +E G++     +   P  A       ++    +  G  P           + + E E++               LP EPR  EEC +I +    G ++L D E++ LV  K I A+ LE+++    RGV IRR+ +         +  LP+R+++Y  VMGACCE+VIGYM +PVGVAGPL LDG+ + VPMATTEGCLVAS NRGC A+   G  +SR+LADGMTRGP+VR P     AE K W+E PE F  IK  FDSTSRFARLQ+L +  AGR LYIRF + TGDAMGMNMISK  E +L +L + FPEM+++++SGN CTDKKPAA+NW++GRGK+V+CEA +P  +V  VLKT+  A+ D+N +KNLVGSAMAGSIGG+NA AAN+VTA++IA GQDAAQNV SSNC+T ++  G   +DLY++CTMPSIE+GTVGGGT L  Q ACL +LGV+G    +PG NA+QLA +VC TV+AGELSLM+ALAAGHLV+SH+ HNRS + +  + G
Sbjct:    1 MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMN-----MFT-----GNNKICGWNYECPKFEEDVLSSDII---ILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTTEHSKVSLGLDEDVSKRIEPSVSLWQFYLSKMISMDIEQVVTLSLAFLLAVKYIFFEQAETESTLSLKNPITSPVATPKKAPDNCCRREPVLSRRN----EKLSSVEEEPGVNQDRKVEVIKPLVAETESTSRATFVLGASGGCSP---------VALGTQEPEIE---------------LPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSTKLPEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRACDSAEVKAWLETPEGFAVIKDAFDSTSRFARLQKLHVTMAGRNLYIRFQSKTGDAMGMNMISKGTEKALVKLQEFFPEMQILAVSGNYCTDKKPAAVNWIEGRGKTVVCEAVIPARVVREVLKTTTEAMIDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQG 880

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BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. SwissProt
Match: gi|123347|sp|P20715.1|HMDH_XENLA (RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase; Short=HMG-CoA reductase)

HSP 1 Score: 680.248 bits (1754), Expect = 0.000e+0
Identity = 386/929 (41.55%), Postives = 554/929 (59.63%), Query Frame = 0

Query:   40 FIRKIFKSHGEFCASQPWEVIVTTFIFLICVLTVGSKHVMMVTEMDSSASSKIKPCLPSDPSCVPEHHSRDWIETLVMAGFYCLAVLHITYRFKKIHLIRSNLIFNIALCYMTFASLLYALIIWSIGNPLKDNLHQAWFLIFLLVDMQKVTRMGQFALSSSHHRRISENVANGMYVLAPTFALDCLAKIFLVGLGSLTRIPQLEAFSWYAVVSVMVNFLVYLTFYPAGLSLVLELMY-CTDGRPRWDVRQIINTLPGEDGQ--TPVVHRVKVVATALLMIAHIIFR---PPFLFSSASGISQPTTTLFS-------------W-------ATTNIEKVLITVVIVALSIKYLFYEDMDEAQE------------LRKTYIEELTRKFAEDSEQEEFNRGNKVEMDRVSNSTDEGISIGSSAKPRPPSCASRHGDDSSSESAWSEVGYLPDLKDQEAQTTDMASSEDEVD-DDENGEKRRIRHHHQLPKEPRSLEECTKIYKGTMDGVEYLIDEEVVHLVEKKVIRAHALESVLNNPTRGVEIRRKYV-EKVAKRD-IGNLPFRNFDYDTVMGACCESVIGYMTMPVGVAGPLNLDGQLFYVPMATTEGCLVASVNRGCSALRTCG-VTSRILADGMTRGPIVRFPNIAKMAEAKEWMEEPENFLQIKSNFDSTSRFARLQRLKLKPAGRELYIRFVAYTGDAMGMNMISKAAEFSLKQLIDVFPEMELVSLSGNMCTDKKPAAINWLDGRGKSVICEATVPGHIVETVLKTSPAALADLNRSKNLVGSAMAGSIGGFNAQAANVVTAVFIATGQDAAQNVASSNCLTQIDVVG---DDLYMTCTMPSIEVGTVGGGTILTAQGACLDLLGVKGCQPASPGANAKQLASVVCATVLAGELSLMSALAAGHLVKSHLRHNRSNLAVGSVAG 923
             + ++F+ HG+F AS PWEVIV T    IC++++      M T  D     KI     + P    +  S D I   ++    C+A+L+I ++F+ +  + S  I  IA  +  F+S +++ ++    +     L++A     LL+D+ K + + +FALSS+    + +N+A GM +L PTF L+ L +  ++G+G+++ + QLE    +  +SV+ N+  ++TF+PA +SLVLEL     +GRP W + Q  + L  E+     PV  RVK++ +  L++ H   R    P   +S S      TT+               W        T ++E+++   + + L++KY+F+E  +                ++K  IE   R+   + EQE+           V  ST E                    + SS E   + +  LP     +A+     SS  E+  +D+N           LP+EPR L+EC +I K    G +YL D EV+ LV  K I A+ LE+++ +P  GV IRR+ + +K+ +R  + +LP++N++Y  VMGACCE+VIGYM +PVGVAGPL L+ + + VPMATTEGCLVAS NRGC A+   G   SR+LADGMTRGP+VR P     AE K W++  E F  IK  FDSTSRFARL RL+   AGR LYIRF + TGDAMGMNMISK  E +L +L + FP++ ++++SGN CTDKKPAAINW++GRGKSV+CEA +P  +V  VLK+S  AL ++N +KN +GSAMAGSIGG+NA AAN+VTA++IA GQDAAQNV SSNC+T ++  G   +DLY++CTMPSIE+GTVGGGT L  Q ACL +LGV+G    +PG NA QLA +VC+TV+AGELSLM+ALAAGHLVKSH+ HNRS + +  + G
Sbjct:    1 MLSRLFRMHGQFVASHPWEVIVGTVTLTICMMSMN-----MFTGND-----KICGWNYACPKFEEDVLSSDII---ILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSKASALAKFALSSNSQDEVRDNIARGMAILGPTFTLEALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFAFMTFFPACVSLVLELSRESREGRPIWQLSQFASVLEEEEDNKPNPVTQRVKMIMSLGLVLVHAHSRWISEPSSQNSTSISDHEVTTMLDDMMPKRVEPSMPLWQFYLSRMVTMDVEQIITLGLALLLAVKYIFFEQTETESTFSMKNPIISPVAVQKKQIESCCRR---EPEQEK----------TVHVSTTE--------------------EASSKEETEAVIKPLPLETSPKAKFIVGDSSPLELSPEDKN-------TMFDLPEEPRPLDECVRILKNPDKGAQYLTDAEVISLVNAKHIPAYKLETMMESPREGVAIRRQMLSDKLPQRSALQSLPYKNYNYSLVMGACCENVIGYMPIPVGVAGPLLLNNKEYQVPMATTEGCLVASTNRGCRAIMLGGGAKSRVLADGMTRGPVVRLPTACDAAEVKAWLDSAEGFKVIKDAFDSTSRFARLGRLQNCVAGRNLYIRFQSKTGDAMGMNMISKVTEQALARLQEEFPDLHVLAVSGNYCTDKKPAAINWIEGRGKSVVCEAIIPAKVVREVLKSSTEALVEVNINKNFIGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITIMEATGPTYEDLYISCTMPSIEIGTVGGGTNLAPQQACLQMLGVQGASTETPGKNACQLAQIVCSTVMAGELSLMAALAAGHLVKSHMVHNRSKINLQDLPG 876

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BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. SwissProt
Match: gi|118573791|sp|P51639.2|HMDH_RAT (RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase; Short=HMG-CoA reductase)

HSP 1 Score: 679.863 bits (1753), Expect = 0.000e+0
Identity = 385/921 (41.80%), Postives = 556/921 (60.37%), Query Frame = 0

Query:   40 FIRKIFKSHGEFCASQPWEVIVTTFIFLICVLTVGSKHVMMVTEMDSSASSKIKPCLPSDPSCVPEHHSRDWIETLVMAGFYCLAVLHITYRFKKIHLIRSNLIFNIALCYMTFASLLYALIIWSIGNPLKDNLHQAWFLIFLLVDMQKVTRMGQFALSSSHHRRISENVANGMYVLAPTFALDCLAKIFLVGLGSLTRIPQLEAFSWYAVVSVMVNFLVYLTFYPAGLSLVLELMY-CTDGRPRWDVRQIINTLPGEDGQ-TPVVHRVKVVATALLMIAHIIFR------PPFLFSSASGIS-----------QPTTTLFSW-----ATTNIEKVLITVVIVALSIKYLFYEDMDEAQELR-KTYIEE--LTRKFAEDS----EQEEFNRGNKVEMDRVSNSTDEGISIGSSAKPRPPSCASRHGDDSSSESAWSEVGYLPDLKDQEAQTTDMASSEDEVDDDENGEKRRIRHHHQLPKEPRSLEECTKIYKGTMDGVEYLIDEEVVHLVEKKVIRAHALESVLNNPTRGVEIRRKYVE-KVAK-RDIGNLPFRNFDYDTVMGACCESVIGYMTMPVGVAGPLNLDGQLFYVPMATTEGCLVASVNRGCSALRTCG-VTSRILADGMTRGPIVRFPNIAKMAEAKEWMEEPENFLQIKSNFDSTSRFARLQRLKLKPAGRELYIRFVAYTGDAMGMNMISKAAEFSLKQLIDVFPEMELVSLSGNMCTDKKPAAINWLDGRGKSVICEATVPGHIVETVLKTSPAALADLNRSKNLVGSAMAGSIGGFNAQAANVVTAVFIATGQDAAQNVASSNCLTQIDVVG---DDLYMTCTMPSIEVGTVGGGTILTAQGACLDLLGVKGCQPASPGANAKQLASVVCATVLAGELSLMSALAAGHLVKSHLRHNRSNLAVGSVAG 923
             + ++F+ HG F AS PWEVIV T    IC++++      M T      ++KI       P    +  S D I   ++    C+A+L+I ++F+ +  + S  I  IA  +  F+S +++ ++    +     L++A     LL+D+ + + + +FALSS+    + EN+A GM +L PTF LD L +  ++G+G+++ + QLE    +  +SV+ N+ V++TF+PA +SLVLEL     +GRP W +      L  E+ +  PV  RVK++ +  L++ H   R      P    +  S +S           +P+ +L+ +      + +IE+V+   + + L++KY+F+E  +    L  K  I    +T K A+D+    E     R  K+     S   D G++     +   P  A    +  +S  A   +G               AS    +   E G         +LP EPR  EEC +I +    G ++L D E++ LV  K I A+ LE+++    RGV IRR+ +  K+A+   +  LP+R+++Y  VMGACCE+VIGYM +PVGVAGPL LDG+ + VPMATTEGCLVAS NRGC A+   G  +SR+LADGM+RGP+VR P     AE K W+E PE F  +K  FDSTSRFARLQ+L +  AGR LYIR  + TGDAMGMNMISK  E +L +L + FPE++++++SGN CTDKKPAAINW++GRGK+V+CEA +P  +V  VLKT+  A+ D+N +KNLVGSAMAGSIGG+NA AAN+VTA++IA GQDAAQNV SSNC+T ++  G   +DLY++CTMPSIE+GTVGGGT L  Q ACL +LGV+G    +PG NA+QLA +VC TV+AGELSLM+ALAAGHLV+SH+ HNRS + +  + G
Sbjct:    1 MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMN-----MFT-----GNNKICGWNYECPKFEEDVLSSDII---ILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLS----SVEEDPGVNQDRKVEVIKPLVA----EAETSGRATFVLG------------ASAASPPLALGAQEPG--------IELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQG 880

[Close]

BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. SwissProt
Match: gi|83305798|sp|Q5R6N3.1|HMDH_PONAB (RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase; Short=HMG-CoA reductase)

HSP 1 Score: 677.552 bits (1747), Expect = 0.000e+0
Identity = 386/919 (42.00%), Postives = 553/919 (60.17%), Query Frame = 0

Query:   40 FIRKIFKSHGEFCASQPWEVIVTTFIFLICVLTVGSKHVMMVTEMDSSASSKIKPCLPSDPSCVPEHHSRDWIETLVMAGFYCLAVLHITYRFKKIHLIRSNLIFNIALCYMTFASLLYALIIWSIGNPLKDNLHQAWFLIFLLVDMQKVTRMGQFALSSSHHRRISENVANGMYVLAPTFALDCLAKIFLVGLGSLTRIPQLEAFSWYAVVSVMVNFLVYLTFYPAGLSLVLELMY-CTDGRPRWDVRQIINTLPGEDGQ-TPVVHRVKVVATALLMIAHIIFR------PPFLFSSASGIS-----------QPTTTLFSW-----ATTNIEKVLITVVIVALSIKYLFYEDMDEAQELR-KTYIEE--LTRKFAEDS--EQEEFNRGNKVEMDRVSNSTDEGISIGSSAKPRPPSCASRHGDDSSSESAWSEVGYLPDLKDQEAQTTDMASSEDEVDDDENGEKRRIRHHHQLPKEPRSLEECTKIYKGTMDGVEYLIDEEVVHLVEKKVIRAHALESVLNNPTRGVEIRRKYVEKVAKR--DIGNLPFRNFDYDTVMGACCESVIGYMTMPVGVAGPLNLDGQLFYVPMATTEGCLVASVNRGCSALRTCG-VTSRILADGMTRGPIVRFPNIAKMAEAKEWMEEPENFLQIKSNFDSTSRFARLQRLKLKPAGRELYIRFVAYTGDAMGMNMISKAAEFSLKQLIDVFPEMELVSLSGNMCTDKKPAAINWLDGRGKSVICEATVPGHIVETVLKTSPAALADLNRSKNLVGSAMAGSIGGFNAQAANVVTAVFIATGQDAAQNVASSNCLTQIDVVG---DDLYMTCTMPSIEVGTVGGGTILTAQGACLDLLGVKGCQPASPGANAKQLASVVCATVLAGELSLMSALAAGHLVKSHLRHNRSNLAVGSVAG 923
             + ++F+ HG F AS PWEVIV T    IC++++      M T      ++KI       P    +  S D I   ++    C+A+L+I ++F+ +  + S  I  IA  +  F+S +++ ++    +     L++A     LL+D+ + + + +FALSS+    + EN+A GM +L PTF LD L +  ++G+G+++ + QLE    +  +SV+ N+ V++TF+PA +SLVLEL     +GRP W +      L  E+ +  PV  RVK++ +  L++ H   R      P    +  S +S           +P+ +L+ +      + +IE+V+   + + L++KY+F+E  +    L  K  I    +T+K   D    +E     N  + D V   T  GI+     +   P  A    +  +   A   VG    L D    ++ + + E E++               LP+EPR  EEC +I      G ++L D E++ LV  K I A+ LE+++    RGV IRR+ + K       +  LP+R+++Y  VMGACCE+VIGYM +PVGVAGPL LDG+ F VPMATTEGCLVAS NRGC A+   G  +SR+LADGMTRGP+VR P     AE K W+E  E F  IK  FDSTSRFARL++L    AGR LYIRF + +GDAMGMNMISK  E +L +L + FPEM+++++SGN CTDKKPAAINW++GRGKS +CEA +P  +V  VLKT+  A+ ++N +KNLVGSAMAGSIGG+NA AAN+VTA++IA GQDAAQNV SSNC+T ++  G   +DLY++CTMPSIE+GTVGGGT L  Q ACL +LGV+G    +PG NA+QLA +VC TV+AGELSLM+ALAAGHLVKSH+ HNRS + +  + G
Sbjct:    1 MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMN-----MFT-----GNNKICGWNYECPKFEEDVLSSDII---ILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWLLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSLKNPITSPVVTQKKVPDDCCRREPMLVRNNQKCDSVEEET--GINRERKVEVIKPLVA----ETDTPNRATFVVGN-SSLLDT---SSVLVTQEPEIE---------------LPREPRPNEECLQILGNAEKGAKFLSDAEIIQLVIAKHIPAYKLETLMETHERGVSIRRQLLSKKLSEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRACDSAEVKAWLETSEGFAVIKEAFDSTSRFARLRKLHTSIAGRNLYIRFQSRSGDAMGMNMISKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSAVCEAVIPAKVVREVLKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDLQG 881

[Close]

BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. SwissProt
Match: gi|123341|sp|P00347.1|HMDH_CRIGR (RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase; Short=HMG-CoA reductase)

HSP 1 Score: 677.167 bits (1746), Expect = 0.000e+0
Identity = 380/908 (41.85%), Postives = 543/908 (59.80%), Query Frame = 0

Query:   40 FIRKIFKSHGEFCASQPWEVIVTTFIFLICVLTVGSKHVMMVTEMDSSASSKIKPCLPSDPSCVPEHHSRDWIETLVMAGFYCLAVLHITYRFKKIHLIRSNLIFNIALCYMTFASLLYALIIWSIGNPLKDNLHQAWFLIFLLVDMQKVTRMGQFALSSSHHRRISENVANGMYVLAPTFALDCLAKIFLVGLGSLTRIPQLEAFSWYAVVSVMVNFLVYLTFYPAGLSLVLELMY-CTDGRPRWDVRQIINTLPGEDGQ-TPVVHRVKVVATALLMIAHIIFR---PPFLFSSASGISQPTTTLFSWATTNIEKVLITVVIVALSIKYLFYEDMDEAQELRKTYIEELTRKFAEDSEQEE-FNRGNKVEMDRVSNSTDEGISIGSSAKPRPPSCASRHGDDSSSESAWSEVGYLPDL-KDQEAQT-------TDMASSEDEVDDDENGE----KRRIRHHHQLPKEPRSLEECTKIYKGTMDGVEYLIDEEVVHLVEKKVIRAHALESVLNNPTRGVEIRRKYVEKVAKR--DIGNLPFRNFDYDTVMGACCESVIGYMTMPVGVAGPLNLDGQLFYVPMATTEGCLVASVNRGCSALRTCG-VTSRILADGMTRGPIVRFPNIAKMAEAKEWMEEPENFLQIKSNFDSTSRFARLQRLKLKPAGRELYIRFVAYTGDAMGMNMISKAAEFSLKQLIDVFPEMELVSLSGNMCTDKKPAAINWLDGRGKSVICEATVPGHIVETVLKTSPAALADLNRSKNLVGSAMAGSIGGFNAQAANVVTAVFIATGQDAAQNVASSNCLTQIDVVG---DDLYMTCTMPSIEVGTVGGGTILTAQGACLDLLGVKGCQPASPGANAKQLASVVCATVLAGELSLMSALAAGHLVKSHLRHNRSNLAVGSVAG 923
             + ++F+ HG F AS PWEVIV T    IC++++      M T      ++KI       P    +  S D I   ++    C+A+L+I ++F+ +  + S  I  IA  +  F+S +++ ++    +     L++A     LL+D+ + + + +FALSS+    + EN+A GM +L PTF LD L +  ++G+G+++ + QLE    +  +SV+ N+ V++TF+PA +SLVLEL     +GRP W +      L  E+ +  PV  RVK++ +  L++ H   R    P   +S +  S+ +  L    +  IE    +V +    +  +   D+++   L   ++  +   F E +E E   +  N +    V+             K  P +C  R           S V   P + +D++ +        T+ AS    V            R      +LP EPR  EEC +I +    G ++L D E++ LV  K I A+ LE+++    RGV IRR+ +         +  LP+R+++Y  VMGACCE+VIGYM +PVGVAGPL LDG+ + VPMATTEGCLVAS NRGC A+   G  +SR+LADGMTRGP+VR P     AE K W+E PE F  IK  FDSTSRFARLQ+L +  AGR LYIRF + TGDAMGMNMISK  E +L +L + FPEM+++++SGN CTDKKPAAINW++GRGK+V+CEA +P  +V  VLKT+  A+ D+N +KNLVGSAMAGSIGG+NA AAN+VTA++IA GQDAAQNV SSNC+T ++  G   +DLY++CTMPSIE+GTVGGGT L  Q ACL +LGV+G    +PG NA+QLA +VC TV+AGELSLM+ALAAGHLV+SH+ HNRS + +  + G
Sbjct:    1 MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMN-----MFT-----GNNKICGWNYECPKFEEDVLSSDII---ILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTTEHSKVSLGLDEDVSKRIEP---SVSLWQFYLSKMISMDIEQVVTLSLAFLLAVKYIFFEQAETESTLSLKNPITSPVVT------------PKKAPDNCCRREPLLVRRSEKLSSVEEEPGVSQDRKVEVIKPLVVETESASRATFVLGASGTSPPVAARTQELEIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSTKLPEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRACDSAEVKAWLETPEGFAVIKDAFDSTSRFARLQKLHVTMAGRNLYIRFQSKTGDAMGMNMISKGTEKALLKLQEFFPEMQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMIDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQG 880

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BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. SwissProt
Match: gi|408360266|sp|Q01237.3|HMDH_MOUSE (RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase; Short=HMG-CoA reductase)

HSP 1 Score: 677.167 bits (1746), Expect = 0.000e+0
Identity = 383/912 (42.00%), Postives = 553/912 (60.64%), Query Frame = 0

Query:   40 FIRKIFKSHGEFCASQPWEVIVTTFIFLICVLTVGSKHVMMVTEMDSSASSKIKPCLPSDPSCVPEHHSRDWIETLVMAGFYCLAVLHITYRFKKIHLIRSNLIFNIALCYMTFASLLYALIIWSIGNPLKDNLHQAWFLIFLLVDMQKVTRMGQFALSSSHHRRISENVANGMYVLAPTFALDCLAKIFLVGLGSLTRIPQLEAFSWYAVVSVMVNFLVYLTFYPAGLSLVLELMY-CTDGRPRWDVRQIINTLPGEDGQ-TPVVHRVKVVATALLMIAHIIFR---PPFLFSSASGISQPTTTLFSWATTNIEKVLITVVIVALSIKYLFYEDMDEAQELRKTYIEELTRKFAEDSEQEE-FNRGNKVEMDRVSNSTDEGISIGSSAKPRPPSCASRHGDDSSSESAWSEVGYLPDLKDQ-------EAQTTD---------MASSEDEVDDDENGEKRRIRHHHQLPKEPRSLEECTKIYKGTMDGVEYLIDEEVVHLVEKKVIRAHALESVLNNPTRGVEIRRKYVE-KVAK-RDIGNLPFRNFDYDTVMGACCESVIGYMTMPVGVAGPLNLDGQLFYVPMATTEGCLVASVNRGCSALRTCG-VTSRILADGMTRGPIVRFPNIAKMAEAKEWMEEPENFLQIKSNFDSTSRFARLQRLKLKPAGRELYIRFVAYTGDAMGMNMISKAAEFSLKQLIDVFPEMELVSLSGNMCTDKKPAAINWLDGRGKSVICEATVPGHIVETVLKTSPAALADLNRSKNLVGSAMAGSIGGFNAQAANVVTAVFIATGQDAAQNVASSNCLTQIDVVG---DDLYMTCTMPSIEVGTVGGGTILTAQGACLDLLGVKGCQPASPGANAKQLASVVCATVLAGELSLMSALAAGHLVKSHLRHNRSNLAVGSVAG 923
             + ++F+ HG F AS PWEVIV T    IC++++      M T      ++KI       P    +  S D I   ++    C+A+L+I ++F+ +  + S  I  IA  +  F+S +++ ++    +     L++A     LL+D+ + + + +FALSS+    + EN+A GM +L PTF LD L +  ++G+G+++ + QLE    +  +SV+ N+ V++TF+PA +SLVLEL     +GRP W +      L  E+ +  PV  RVK++ +  L++ H   R    P   +S +  ++ +  L    +  IE    +V +    +  +   D+++   L   ++  +   F E +E E   +  N +    V++   +      +   R P    R+   SS E    + G   + K +       EA+TT          +AS    +   E G         +LP EPR  EEC +I +    G ++L D E++ LV  K I A+ LE+++    RGV IRR+ +  K+A+   +  LP+R+++Y  VMGACCE+VIGYM +PVGVAGPL LDG+ + VPMATTEGCLVAS NRGC A+   G  +SR+LADGMTRGP+VR P     AE K W+E PE F  IK  FDSTSRFARLQ+L +  AGR LYIRF + TGDAMGMNMISK  E +L +L + FP+M+++++SGN CTDKKPAAINW++GRGK+V+CEA +P  +V  VLKT+  A+ D+N +KNLVGSAMAGSIGG+NA AAN+VTA++IA GQDAAQNV SSNC+T ++  G   +DLY++CTMPSIE+GTVGGGT L  Q ACL +LGV+G    +PG NA+QLA +VC TV+AGELSLM+ALAAGHLV+SH+ HNRS + +  + G
Sbjct:    1 MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMN-----MFT-----GNNKICGWNYECPKFEEDVLSSDII---ILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQAKVSLGLDEDVSKRIEP---SVSLWQFYLSKMISMDIEQVITLSLAFLLAVKYIFFEQAETESTLSLKNPITSPVVTSKKAQ-----DNCCRREPLLVRRNQKLSSVEE---DPGANQERKVEVIKPLVVEAETTSRATFVLGASVASPPSALGTQEPG--------IELPIEPRPNEECLQILENAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSTKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMTRGPVVRLPRACDSAEVKTWLETPEGFAVIKEAFDSTSRFARLQKLHVTMAGRNLYIRFQSRTGDAMGMNMISKGTEKALLKLQEFFPDMQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQG 880

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BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. nr
Match: gi|1279713396|ref|XP_022901116.1| (3-hydroxy-3-methylglutaryl-coenzyme A reductase-like [Onthophagus taurus] >gi|1279713398|ref|XP_022901117.1| 3-hydroxy-3-methylglutaryl-coenzyme A reductase-like [Onthophagus taurus])

HSP 1 Score: 732.25 bits (1889), Expect = 0.000e+0
Identity = 421/913 (46.11%), Postives = 573/913 (62.76%), Query Frame = 0

Query:   45 FKSHGEFCASQPWEVIVTTFIFLICVLTVGSKHVMMVTEMDSSASSK-IKPCLPSDPSCVPEHHSRDWIETLVMAGFYCLAVLHITYRFKKIHLIRSNLIFNIALCYMTFASLLY-ALIIWSIGNPLKDNLHQAWFLIFLLVDMQKVTRMGQFALSSSHHRRISENVANGMYVLAPTFALDCLAKIFLVGLGSLTRIPQLEAFSWYAVVSVMVNFLVYLTFYPAGLSLVLELMYCTDGRPRWDVRQIIN-TLPGEDGQT-PVVHRVKVVATALLMIAHIIFRPPFLFSSASG---------ISQPT------TTLFSWATTNIEKVLITVVIVALSIKYLFYEDMDEAQELRKTYIEELTRKFAEDSEQEEFNRGNKVEMDRVS---NSTDEGISIGSSAKPRPPSCASRHGDDSSSESAWSEVGYLPDLKDQEAQTT--DMASSEDEVDDDENGEKRRIRHHHQLPKEPRSLEECTKIYKGTMDGVEYLIDEEVVHLVEKKVIRAHALESVLNNPTRGVEIRRKYVEKVAKRD--IGNLPFRNFDYDTVMGACCESVIGYMTMPVGVAGPLNLDGQLFYVPMATTEGCLVASVNRGCSALRTCGVTSRILADGMTRGPIVRFPNIAKMAEAKEWMEEPENFLQIKSNFDSTSRFARLQRLKLKPAGRELYIRFVAYTGDAMGMNMISKAAEFSLKQLIDVFPEMELVSLSGNMCTDKKPAAINWLDGRGKSVICEATVPGHIVETVLKTSPAALADLNRSKNLVGSAMAGSIGGFNAQAANVVTAVFIATGQDAAQNVASSNCLTQID---VVGDDLYMTCTMPSIEVGTVGGGTILTAQGACLDLLGVKGCQPASPGANAKQLASVVCATVLAGELSLMSALAAGHLVKSHLRHNRSNLAV-GSVAGPESM 927
            F+ HGEFCA+ PWEVIV  F    C+LT           MD     K ++ C    P C P     +  + ++M    CLAVL+  Y+ + ++ + S  I  IA  +  F+S ++ + +I  + N + D L  A F   LL+D+ K   + +FALS+++   +  N+A GM VL PT  LD +    ++G+G+L+   + E  S++A +SV+VN++V++TFYPA LSL+ EL        R + R II+  L  ED ++ PVV RVK++ +  LM  H+  R PF      G         +S  T      + +  W T + + ++I ++++AL +K++F+E+ +E Q++R         + ++  EQ   N+      +R S   N    G+    S             DDS++             +D+E QT    + SS+ EV   +             PK+PR L+EC  IYK    G   L DEEV+ LV+ K I  + LE  +NNP RGV IRRK   +  K D  + NLP++++DY  VMGACCE+VIGY+ +P+G+ GPL LDG+L YVPMATTEGCLVAS NRGC AL   GVTSRI+ DGMTR P+VRFP +A+ +EA  WME P+NF +IK +FDS+SR+ARL RL +  AGR+L+IRF A TGDAMGMNM+SK  E SL+ + + +PEME++SLSGN CTDKKPAA+NW++GRGKSV+CEA VP  ++ TVLKTS   L D+N SKN+VGSAMAGSIGGFNA +ANVVTA++IATGQD AQNV SSNC+T ++     G+DLY++CTMPSIE+GTVGGGTIL  Q ACLD+L VKG   A+PG NAKQLA +VCATVLAGELSLMSALAAGHLVKSHL+HNRS+  + G VA  +S+
Sbjct:    6 FRKHGEFCATHPWEVIVAIFTLTACMLT-----------MDKGQWPKPVRTC----PGC-PNDGEYNPADVILMTAIRCLAVLYAYYQLRHLNTLGSKCILGIAGVFTVFSSFVFISTVINFLRNDVND-LKDALFFFLLLIDLSKAALLAEFALSAANQEEVKNNIATGMSVLGPTITLDTIVVTLVIGVGTLSGAHRWEVLSYFACLSVIVNYIVFMTFYPACLSLISEL-----SNLRINYRSIISLALKAEDHKSNPVVQRVKIIMSVGLMCVHVHSRLPFREDLLGGNNPRAVEHFVSNNTEDTALHSYIMKWLTLSADHIVILILLLALVVKFIFFENEEEFQQIRS--------QLSQSGEQFLLNQKKTAREERTSILRNRFKSGMPFFIS-------------DDSTTT------------EDREVQTEFPYIDSSDVEVKPSK-------------PKDPRPLDECLTIYKSEW-GASTLSDEEVIRLVKNKTIAPYQLEKAVNNPERGVGIRRKIFGENGKFDEALINLPYKDYDYSKVMGACCENVIGYLPVPIGIVGPLKLDGKLMYVPMATTEGCLVASTNRGCRALIQNGVTSRIVKDGMTRAPVVRFPTLAQASEAMAWMENPDNFTKIKEHFDSSSRYARLTRLHINIAGRQLFIRFEAKTGDAMGMNMVSKGTEQSLRFVQNSYPEMEILSLSGNFCTDKKPAAVNWIEGRGKSVVCEAIVPAAVISTVLKTSVKTLVDVNISKNMVGSAMAGSIGGFNAHSANVVTAIYIATGQDPAQNVGSSNCITLMEPCGETGEDLYISCTMPSIEIGTVGGGTILAPQAACLDILNVKGANIANPGENAKQLARIVCATVLAGELSLMSALAAGHLVKSHLKHNRSSTTMSGDVATGKSL 849

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BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. nr
Match: gi|451935537|gb|AGF87101.1| (3-hydroxy-3-methylglutaryl coenzyme A reductase [Epicauta chinensis])

HSP 1 Score: 731.095 bits (1886), Expect = 0.000e+0
Identity = 402/910 (44.18%), Postives = 563/910 (61.87%), Query Frame = 0

Query:   43 KIFKSHGEFCASQPWEVIVTTFIFLICVLTVGSKHVMMVTEMDSSASSKIKPCLPSDPSCVPEHHSRDWIETLVMAGFYCLAVLHITYRFKKIHLIRSNLIFNIALCYMTFASLLYALIIWSIGNPLKDNLHQAWFLIFLLVDMQKVTRMGQFALSSSHHRRISENVANGMYVLAPTFALDCLAKIFLVGLGSLTRIPQLEAFSWYAVVSVMVNFLVYLTFYPAGLSLVLELMYCTD--GRPRWDVRQIINTLPGEDGQT-PVVHRVKVVATALLMIAHIIFRPPFLFSSASGI---------SQPTTT-------LFSWATTNIEKVLITVVIVALSIKYLFYEDMDE-AQELRKTYIEELTRKFAEDSEQEEFNRGNKVEMDRVSNSTDEGISIGSSAKPRPPSCASRHGDDSSSESAWSEVGYLPDLKDQEAQT--------TDMASSEDEVDDDENGEKRRIRHHHQLPKEPRSLEECTKIYKGTMDGVEYLIDEEVVHLVEKKVIRAHALESVLNNPTRGVEIRRKYVEKVAK--RDIGNLPFRNFDYDTVMGACCESVIGYMTMPVGVAGPLNLDGQLFYVPMATTEGCLVASVNRGCSALRTCGVTSRILADGMTRGPIVRFPNIAKMAEAKEWMEEPENFLQIKSNFDSTSRFARLQRLKLKPAGRELYIRFVAYTGDAMGMNMISKAAEFSLKQLIDV-FPEMELVSLSGNMCTDKKPAAINWLDGRGKSVICEATVPGHIVETVLKTSPAALADLNRSKNLVGSAMAGSIGGFNAQAANVVTAVFIATGQDAAQNVASSNCLTQIDVVG---DDLYMTCTMPSIEVGTVGGGTILTAQGACLDLLGVKGCQPASPGANAKQLASVVCATVLAGELSLMSALAAGHLVKSHLRHNRSNLAV 918
            ++FK HGEFCA+ PWEVIV T    +C+LTV  +            ++  KP L +   C+ E    +  + +VM    CLAVL+  Y+F  +  + S  I  IA  +  F+S ++   + ++      +L  A F   LL+D+ K   + Q ALS+S+   +  N+A GM +L PT  LD + +  ++G+G+L+ + +LE  S++A +SV+VN++V++TFYPA LSL+LEL   T+  G+ +     I      ED ++ PVV RVK++ +A LM+ H   R PF       I         +Q  T        +  W T + + + I ++++AL +K++F+E+ ++ A +LR    E    K  +  ++  F +  +          D  I+  S A                           P+ +D+  QT        TD++ +E+E D                 +  R+L+EC +IY  T  G  +L D+EV+ LV+ K I A+ +E  + +P RGV IRRK V   AK    + NLP++N+DY  VMGACCE+VIGYM +PVG+AGPL LDG+  YVPMATTEGCLV S NRGC AL  CG+ S I+ADGMTRGP+VRFP++ + +EA  WM+  ENF  IK +FD++SRFARL +L +K AGR L+IRF A TGDAMGMNM+SK  E SLK +  V FP+ME++SLSGN CTDKKPAA+NW++GRGKSV+CEA +P ++V  +LKT+ +AL D+N SKN++GSA+AGSIGGFNA AAN+VTA+FIATGQD AQN+ SSNC+T ++  G   +DLY++CTMPSIE+GT+GGGTIL AQ +CL++LGVKG     PG NA +LA +VCATVLAGELSLM+AL AGHLVKSHLRHNRS   +
Sbjct:    5 QLFKVHGEFCAAYPWEVIVATLTLAVCMLTVDQQQ---------HPTAPPKPILRNCAGCLHEAE-YNAADVIVMTLIRCLAVLYSYYQFCNLQRLGSKYILGIAGLFTVFSSFIFTTTVLNLLRIDMADLKDALFFFSLLIDLSKAATLAQSALSASNQDEVKSNIARGMAILGPTITLDTIVETLVIGVGTLSGVHRLEMLSYFACLSVVVNYVVFMTFYPACLSLILELSRTTNIYGKKQ---SLIARAWKEEDHKSNPVVQRVKLIMSAGLMLVHARSRWPFKADEVDNIGPLVVEQHMAQNRTENTALHEYMMKWVTVSADHIAILILLLALVVKFIFFENKEDLALQLRAHITESEDNKKPDLPQKMPFLKPQQTFFLE-----DRDIAEDSKA---------------------------PEFEDKGVQTEKFKRESSTDLSETENETD-----------------QFCRNLDECRRIYNDTDLGGTFLTDDEVISLVQSKDIPAYQIEKAVEDPVRGVGIRRKIVGHEAKILEALTNLPYKNYDYSKVMGACCENVIGYMPVPVGIAGPLKLDGRNVYVPMATTEGCLVVSTNRGCRALSECGIISCIVADGMTRGPVVRFPSVKQASEAMVWMKSNENFALIKQHFDASSRFARLSKLLIKIAGRYLFIRFEAKTGDAMGMNMVSKGTELSLKYIQKVHFPDMEILSLSGNFCTDKKPAAVNWIEGRGKSVVCEAIIPANVVTKILKTNASALVDVNNSKNMIGSAVAGSIGGFNAHAANIVTAIFIATGQDPAQNIGSSNCMTLMETWGENDEDLYISCTMPSIEIGTIGGGTILPAQSSCLEMLGVKGPHQEYPGENANRLARIVCATVLAGELSLMAALTAGHLVKSHLRHNRSTTTI 852

[Close]

BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. nr
Match: gi|9817458|gb|AAD20975.2| (3-hydroxy-3-methylglutaryl coenzyme A reductase [Ips paraconfusus])

HSP 1 Score: 729.169 bits (1881), Expect = 0.000e+0
Identity = 408/898 (45.43%), Postives = 563/898 (62.69%), Query Frame = 0

Query:   40 FIRKIFKSHGEFCASQPWEVIVTTFIFLICVLTVGSKHVMMVTEMDSSASSKIKPCLPSDPSCV--PEHHSRDWIETLVMAGFYCLAVLHITYRFKKIHLIRSNLIFNIALCYMTFASLLYALIIWSIGNPLKDNLHQAWFLIFLLVDMQKVTRMGQFALSSSHHRRISENVANGMYVLAPTFALDCLAKIFLVGLGSLTRIPQLEAFSWYAVVSVMVNFLVYLTFYPAGLSLVLELMYCTDGRPRWDVRQIINTLPGEDGQTPVVHRVKVVATALLMIAHIIFRPPFLFSSASGISQPTTTLFS--------------WATTNIEKVLITVVIVALSIKYLFYE--DMDEAQELRKTYIEELTRKFAEDSEQEEFNRGNKVEMDRVSNSTDEGISIGSSAKPRPPSCASRHGDDSSSESAWSEVGYLPDLKDQEAQTTDMASSEDEVDDDENGEKRRIRHHHQLPKEPRSLEECTKIYKGTMDGVEYLIDEEVVHLVEKKVIRAHALESVLNNPTRGVEIRRKYVEKV--AKRDIGNLPFRNFDYDTVMGACCESVIGYMTMPVGVAGPLNLDGQLFYVPMATTEGCLVASVNRGCSALRTCGVTSRILADGMTRGPIVRFPNIAKMAEAKEWMEEPENFLQIKSNFDSTSRFARLQRLKLKPAGRELYIRFVAYTGDAMGMNMISKAAEFSLKQLIDVFPEMELVSLSGNMCTDKKPAAINWLDGRGKSVICEATVPGHIVETVLKTSPAALADLNRSKNLVGSAMAGSIGGFNAQAANVVTAVFIATGQDAAQNVASSNCLTQID---VVGDDLYMTCTMPSIEVGTVGGGTILTAQGACLDLLGVKGCQPASPGANAKQLASVVCATVLAGELSLMSALAAGHLVKSHLRHNRS 914
             + ++F +HGEFC + PWEVIV T     C+LTV  ++ +  T          KP   S   C+   E+++ D I   ++     LAVL+  Y+F+K+H + S  I  IA  +  F+S ++   + ++      +L  A F   LL+D+ K   + QFAL+S +      N+A G+  L PT  LD + +  ++G+G+L+ + +LE  SW+A +SV+VN++V++ FYPA LSL+LEL   T+     D   I      E    PVV RVK++ +  LMI H+  R PF  S    I       F+              W     + ++I ++I AL IK LF+E  D+ E ++ ++T +E    + AE++E+EE     +V  ++                 R P  +    +D S E+ +         +D+E QT    +SE     +++           +PK  ++LE+C KIY     G   L DEE++ L++ + I  + +E  ++NP RGV IRRK + +   A + +  LP+RN+DY  VMGACCE+VIGYM +PVG AGPL LDG+  YVPMATTEGCLVAS NRGC AL+  GVTSRI+ADGMTRGP+VRFP+I + ++A +W+++  NF  IK  FDS+SRFARLQR+ +K AGR L+IRFVA TGDAMGMNM+SK  E+SLK +   F +ME++SLSGN CTDKKPAA+NW++GRGKSV+CEA VP  IV  +LKT+  AL D+N SKN+VGSA+AGSIGGFNA AAN+VTA+F+ATGQD AQNV SSNC+T ++     G+DLY++CTMPSIE+GT+GGGTIL  QG CL++LGV+G   A PGANA QLA +V ATVLAGELSLMSALAAGHLV+SHLRHNRS
Sbjct:    1 MVSRLFLAHGEFCTNHPWEVIVATLTLTACMLTVERQNPIPPT----------KPITTSCQGCIQEAEYNAADLISMTILRS---LAVLYCYYQFRKLHKLGSRYILGIAELFTVFSSFIFTTTVLNLLRVEVSDLKDALFFFLLLIDLSKAGMLAQFALTSQNEIEGKNNIAKGLAELGPTITLDTVVETLVIGVGTLSGVERLEMLSWFACLSVLVNYVVFMAFYPACLSLILELSRSTNFYKTKDPWMIFAFKEEEHKSNPVVQRVKLIMSVGLMIVHVHSRWPFKDSEVYNIEPLVQQSFNNTEESNSLHGYFERWLALGADHIVILILITALLIKLLFFEIQDLTEIRD-QETQVEPEKSEKAENTEKEELKVVQEVRENK-----------------RMPMFS--LSEDDSCETTF---------QDKEVQTQTPYNSEAHSSSEDD-----------IPKVCKTLEDCLKIYNNVDMGATALTDEEIILLIKNRHIAGYQIEKAVDNPERGVGIRRKILGRDLDAPKVLEGLPYRNYDYSLVMGACCENVIGYMPIPVGYAGPLVLDGKEIYVPMATTEGCLVASTNRGCRALKEAGVTSRIVADGMTRGPVVRFPSIIRASQAMQWIQD--NFDGIKEQFDSSSRFARLQRVTMKIAGRLLFIRFVATTGDAMGMNMLSKGTEYSLKFVQRAFEDMEILSLSGNFCTDKKPAAVNWIEGRGKSVVCEAIVPAKIVANILKTNVHALVDVNNSKNMVGSAVAGSIGGFNAHAANIVTAIFLATGQDPAQNVGSSNCMTLMEPWGPTGEDLYISCTMPSIEIGTIGGGTILPPQGTCLEMLGVRGSNIAEPGANASQLAKIVGATVLAGELSLMSALAAGHLVRSHLRHNRS 843

[Close]

BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. nr
Match: gi|751231033|ref|XP_011169052.1| (PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase [Solenopsis invicta] >gi|751231035|ref|XP_011169053.1| PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase [Solenopsis invicta])

HSP 1 Score: 728.013 bits (1878), Expect = 0.000e+0
Identity = 399/919 (43.42%), Postives = 564/919 (61.37%), Query Frame = 0

Query:   45 FKSHGEFCASQPWEVIVTTFIFLICVLTVGSKHVMMVTEMDSSASSKIKPCLPSDPSCVPEHHSR------DWIETLVMAGFYCLAVLHITYRFKKIHLIRSNLIFNIALCYMTFASLLYALIIWSIGNPLKDNLHQAWFLIFLLVDMQKVTRMGQFALSSSHHRRISENVANGMYVLAPTFALDCLAKIFLVGLGSLTRIPQLEAFSWYAVVSVMVNFLVYLTFYPAGLSLVLELMYCTD--GRPRWDVRQIINTLPGEDGQ-TPVVHRVKVVATALLMIAHIIFRPPFLFSSASGISQPTTT--------------------LFSWATTNIEKVLITVVIVALSIKYLFYEDMDE--AQELRKTYIEELTRKFAEDSEQEEFNRGNK-----VEMDRVSNST--DEGISIGSSAKPRPPSCASRHGDDSSSESAWSEVGYLPDLKDQEAQTTDMASSEDEVDDDENGEKRRIRHHHQLPKEPRSLEECTKIYKGTMDGVEYLIDEEVVHLVEKKVIRAHALESVLNNPTRGVEIRRKYVEKVAK--RDIGNLPFRNFDYDTVMGACCESVIGYMTMPVGVAGPLNLDGQLFYVPMATTEGCLVASVNRGCSALRTCGVTSRILADGMTRGPIVRFPNIAKMAEAKEWMEEPENFLQIKSNFDSTSRFARLQRLKLKPAGRELYIRFVAYTGDAMGMNMISKAAEFSLKQLIDVFPEMELVSLSGNMCTDKKPAAINWLDGRGKSVICEATVPGHIVETVLKTSPAALADLNRSKNLVGSAMAGSIGGFNAQAANVVTAVFIATGQDAAQNVASSNCLTQID---VVGDDLYMTCTMPSIEVGTVGGGTILTAQGACLDLLGVKGCQPASPGANAKQLASVVCATVLAGELSLMSALAAGHLVKSHLRHNRSNLAVGS 920
            F+ +G FCA  PWEVIVT      C+L +           ++    + +  LP    C    H+R      +  + +VM    CLAVL   ++F+ +  + S  I  IA  +  F+S+++   + + G     NL  A F  FLL+D+ K   + Q+ALSS +   +  N+A GM +L P   +D L +  L+ +GSL+ I +LE    +A + V+VN++V++TFYPA LSL+LEL    +  G+   D   I+  L  ED +  PVV RVK +  A L + H   R PF            T+                    L +W +TN +K+++ ++++A+++K++F++D ++  A+ LR    E+  ++  ++ E+       K       +D ++ +T   E   + S  K   P+        S     W       +  D+E QT  +   +++  + +   K          K PRSLE+C +IY+  + G + L +EEV+ LV  K I A+ LE  ++NP RGV+IRR  V    K  ++I NLP+RN+DY  V+GACCE+VIGY+ MPVG+ GPL +DGQ ++VPMATTEGCLVAS NRG  AL  CGVT+R+ ADGMTR P+V+FPNI +  EA  W+E+P+NF ++K +FD TSRFARL+++  + AG+++++RFVA TGDAMGMNM+S+  E SL+ L   FP+M+++SLSGN+CTDKKPAA+NW++GRGKSV+CEA +P  +V  VLKTS   L  LN  KNL+GSA+AGSIGGFNA AAN+VTA+FIATGQD AQNV SSNCLT ++   V G DL MTCTMPSIEVGT+GGGT+L AQGACL +LG+KG  P  PG NAK+LA +VCATVLA ELSLM+ALA+G LVKSHLRHNRS+  V +
Sbjct:    6 FEKYGLFCAGHPWEVIVTILTLTACMLNI-----------ETGNRQEREEDLPYAAYC---RHNRCDVTDLNAADIIVMTIIRCLAVLFTYHQFRNLQKMGSKYILGIAGLFTVFSSVMFTSSVINFGRSDIANLKDALFFFFLLIDLSKAATLAQYALSSRNQEEVKTNIARGMSLLGPAITVDTLVETLLISIGSLSGIRRLEILCTFACLGVIVNYIVFMTFYPACLSLILELSRGNNNMGQLSADRMFIMQPLNEEDQKPNPVVERVKKIMIAGLFVVHANSRWPFKSEEGKYTKMAATSTSLNATNDSDHIENTDLEEHLMTWLSTNADKIVVLILVLAVAVKFIFFDDRNDVVAKRLRFREEEKEEKEQQQEEEEMIVEEKGKFLDGSANLDDITVNTWLQERYGVTSGVKSDVPTIREPVFPLSGVGGGWESDESDKEYSDKEVQTDVVYHDQNDSGEIDTSPKS---------KTPRSLEDCLEIYQSQL-GAKALTNEEVIQLVNHKDIAAYQLEKAVDNPERGVDIRRNIVGTAGKFIKEITNLPYRNYDYKKVLGACCENVIGYVPMPVGIVGPLLIDGQFYHVPMATTEGCLVASTNRGSRALLKCGVTTRVTADGMTRAPVVQFPNIVRACEAISWIEQPQNFQELKKSFDQTSRFARLKKIHTRIAGQDVHLRFVATTGDAMGMNMLSQGTEKSLQTLQTYFPDMKIISLSGNLCTDKKPAAVNWIEGRGKSVVCEAIIPADVVARVLKTSVPELVKLNHKKNLIGSALAGSIGGFNAHAANIVTAIFIATGQDPAQNVGSSNCLTLMEPWGVDGKDLRMTCTMPSIEVGTIGGGTVLPAQGACLGMLGIKGGHPTEPGQNAKKLAQIVCATVLAAELSLMAALASGDLVKSHLRHNRSSALVNN 900

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BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. nr
Match: gi|939255167|ref|XP_014247324.1| (3-hydroxy-3-methylglutaryl-coenzyme A reductase-like [Cimex lectularius] >gi|1351645028|ref|XP_024085535.1| 3-hydroxy-3-methylglutaryl-coenzyme A reductase-like [Cimex lectularius])

HSP 1 Score: 726.087 bits (1873), Expect = 0.000e+0
Identity = 408/902 (45.23%), Postives = 565/902 (62.64%), Query Frame = 0

Query:   45 FKSHGEFCASQPWEVIVTTFIFLICVLTVGSKHVMMVTEMDSSASSKIKPCLPSDPSCVPEHHSRDWIETLVMAGFYCLAVLHITYRFKKIHLIRSNLIFNIALCYMTFASLLYALIIWSIGNPLKDNLHQAWFLIFLLVDMQKVTRMGQFALSSSHHRRISENVANGMYVLAPTFALDCLAKIFLVGLGSLTRIPQLEAFSWYAVVSVMVNFLVYLTFYPAGLSLVLELMYCTD--GRPRWDVRQIINTLP-GEDGQTPVVHRVKVVATALLMIAHIIFR-------------PPFLFSSASGISQPTTT------LFSWATTNIEKVLITVVIVALSIKYLFYEDMDEAQELRKTYIEELTRKFAEDSEQEEFNRGNKVEMDRVSNSTDEGISIGSSAKPRPPSCASRHGDDSSSESAWSEVGYLPDLKDQEAQTTDMASSEDEVDDDENGEKRRIRHHHQLPKEPRSLEECTKIYKGTMDGV-EYLIDEEVVHLVEKKVIRAHALESVLNNPTRGVEIRRKYVEKVAK--RDIGNLPFRNFDYDTVMGACCESVIGYMTMPVGVAGPLNLDGQLFYVPMATTEGCLVASVNRGCSALRTCGVTSRILADGMTRGPIVRFPNIAKMAEAKEWMEEPENFLQIKSNFDSTSRFARLQRLKLKPAGRELYIRFVAYTGDAMGMNMISKAAEFSLKQLIDVFPEMELVSLSGNMCTDKKPAAINWLDGRGKSVICEATVPGHIVETVLKTSPAALADLNRSKNLVGSAMAGSIGGFNAQAANVVTAVFIATGQDAAQNVASSNCLTQIDVVGD---DLYMTCTMPSIEVGTVGGGTILTAQGACLDLLGVKGCQPASPGANAKQLASVVCATVLAGELSLMSALAAGHLVKSHLRHNRSNLAV 918
            +++HGEFCA+ PWEVIV T     C+L++ +  +  +T     AS  I  C    P  VP       ++ +VMA   C+AVL+  Y+F+ +H + S  I  IA  +  F+S +++  + +  +    +L  A F   LL+D+ + T + QFALS+S    + +N+A G  +L PT  LD + +   + +G+L+ I +LE    +A +SV+VN+LV++TFYPA LSL+LEL    +   +P W     ++ +  GE    PV+ RVK++ +A L++ H+  R              P + S  +  S  T        L+ W T + + V+I ++++AL++K++F+ED                        +EE   G+ +        T +GI I    KP      +     +  ES   +   +  ++    ++T + ++   V D                K  R LE+C  IYK   DG+ E L D EV  LVEK  I  ++LE  +NNP RGV+IRRK V  V      I +LP++N+DY  V+GACCE+V+GYM +PVG+AGPL LDGQLF+VPMATTEGCLVAS NRGC AL  CGVTSR++ADGMTRGP+VRF +I + +E  EW++ PENF++IK +FDSTSRFARL +L ++ AGR L+IRFVA TGDAMGMNM SK  E +L  +  +F +ME++SLSGN C DKKPAA+NW++GRGKSV+C+ATVP ++V+ +LKTS  AL D+N SKNLVGSA+AGSIGGFNA AAN+VTA+FIATGQD AQNV+SSNC+T ++  GD   DL+++CTMPSIE+GTVGGGT L AQ ACLD LGV+G     PG NA  LA +VCA+VLAGELSL+SALA+GHLVKSHLRHNRS+ AV
Sbjct:    5 YRAHGEFCANHPWEVIVATLTLTACILSIDTGGIYSLT----PASHSIYTC----P--VPPCQEYSAVDVIVMASIRCMAVLYSYYQFRNLHKLGSKYILGIAALFTVFSSFVFSSGVINCLHGNISDLEDALFFFLLLIDLSRATILAQFALSASTQDEVKKNIARGFELLGPTLTLDTVVETLAISVGTLSGIRRLELLCSFACMSVVVNYLVFMTFYPACLSLILELSKSKEPGKKPSWHYNSEVHDIKDGEQKPNPVLQRVKIIMSAGLVVVHLHSRWTIKGLEGQEHNVLPLVSSEHTVPSNSTDNEEIRGYLYRWITVSADHVVILILLLALTVKFVFFED------------------------KEEIIAGDVI--------TSKGIGI----KPFIGEEINTKNFHTQRESKLIQTEEMFAMELHALESTAVNTAITNVHDS---------------KLIRPLEDCLSIYK--KDGMAENLSDLEVELLVEKGHIPTYSLEKAVNNPERGVKIRRKIVGSVGGFPEAISSLPYKNYDYSKVLGACCENVVGYMPIPVGMAGPLLLDGQLFHVPMATTEGCLVASTNRGCRALMNCGVTSRVVADGMTRGPVVRFKSITRASEVMEWLQVPENFIKIKESFDSTSRFARLSKLHMRIAGRYLFIRFVATTGDAMGMNMASKGTEVALNYIQTLFEDMEILSLSGNFCADKKPAAVNWIEGRGKSVVCQATVPSNVVKKILKTSVQALVDVNISKNLVGSAVAGSIGGFNAHAANIVTAIFIATGQDPAQNVSSSNCMTLMEPWGDEGQDLHVSCTMPSIEIGTVGGGTQLPAQAACLDFLGVRGAHDTCPGQNANMLARIVCASVLAGELSLLSALASGHLVKSHLRHNRSSAAV 843

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BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. nr
Match: gi|998503484|ref|XP_015511853.1| (PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase [Neodiprion lecontei] >gi|998503486|ref|XP_015511854.1| PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase [Neodiprion lecontei])

HSP 1 Score: 725.702 bits (1872), Expect = 0.000e+0
Identity = 409/915 (44.70%), Postives = 571/915 (62.40%), Query Frame = 0

Query:   40 FIRKIFKSHGEFCASQPWEVIVTTFIFLICVLTV--GSKHVMMVTEMDSSASSKIKPCLPSDPSCVPEHHSRDWIETLVMAGFYCLAVLHITYRFKKIHLIRSNLIFNIALCYMTFASLLYALIIWSIGNPLKDNLHQAWFLIFLLVDMQKVTRMGQFALSSSHHRRISENVANGMYVLAPTFALDCLAKIFLVGLGSLTRIPQLEAFSWYAVVSVMVNFLVYLTFYPAGLSLVLELMY--CTDGRPRWDVRQIINTLPGEDGQ-TPVVHRVKVVATALLMIAHIIFRPPFLFSSASGISQPTTT-----------------------LFSWATTNIEKVLITVVIVALSIKYLFYEDMDE-AQELRKTYIEELTRKFAEDSEQEEFNRGNKVEMDRVSNSTDEGISIGSSAKPRPPSCASRHGDDSSSESAWSEVGYLPDLK--DQEAQTTDMASSEDEVDDDENGEKRRIRHHHQLPKEPRSLEECTKIYKGTMDGVEYLIDEEVVHLVEKKVIRAHALESVLNNPTRGVEIRRKYVEKVAK--RDIGNLPFRNFDYDTVMGACCESVIGYMTMPVGVAGPLNLDGQLFYVPMATTEGCLVASVNRGCSALRTCGVTSRILADGMTRGPIVRFPNIAKMAEAKEWMEEPENFLQIKSNFDSTSRFARLQRLKLKPAGRELYIRFVAYTGDAMGMNMISKAAEFSLKQLIDVFPEMELVSLSGNMCTDKKPAAINWLDGRGKSVICEATVPGHIVETVLKTSPAALADLNRSKNLVGSAMAGSIGGFNAQAANVVTAVFIATGQDAAQNVASSNCLTQIDVV---GDDLYMTCTMPSIEVGTVGGGTILTAQGACLDLLGVKGCQPASPGANAKQLASVVCATVLAGELSLMSALAAGHLVKSHLRHNRSNLAV 918
             + +IF +HG FCAS   EVIV T     C+LT+  GS H     + D S  +  K C   +  C  +    +  + +VM    CLAVL+  Y+F  +H + S  I  IA  +  F+S ++   + +       +L  A F   LL+D+ K   + Q ALSS     +  N+A GM +L P+  LD L +  L+G+G+L+ + +LE    +A +SV+VN+++++TFYPA LSL+LEL     T G+   D   ++++L  ED +  PVV RVK++ +A L++ H   R PF     + +++ T +                          W + + + ++I ++++ L+IK++F+ED  E  ++LR T   E  ++ +E++ Q          +D VS     G  +     P  P         S     W EVG    +K  D+E QT      E  +   +N  +    +    P+  RS+EEC  IYK  + G   L D EV+ LV+ K I A+ LE  + +  RGV +RR  V +  K    + +LP++N+DY  V+G+CCE+VIGY+ +PVG+AGPL +DG+L +VPMATTEGCL+AS NRG  AL  CGVTSR++ADGMTRGP+VRFPNI++ +EA  WM++ +NF  +KS+FDSTSR+ARL R+ ++ AGR L+IRFVA TGDAMGMNM+SK  E SL+ +  +F +ME++SLSGN CTDKKPAA+NW++GRGKSV+CEA VP  IV TVLKTS  AL D+N SKNL+GSA+AGSIGG+NA AANVVTA++IATGQD AQNV SSNC+T ++     G+DLY++CTMPSIE+GTVGGGT L AQGACL +LG KG  P +PG NA ++A VVCATVLAGELSLM+AL AGHLVKSHLRHNRS+ A+
Sbjct:    1 MVARIFAAHGRFCASHSLEVIVGTLTLTACMLTLETGSNH-----QRDKSLHTAGKHCW--NGRCSGD--DLNAADMIVMTIIRCLAVLYSYYQFCNLHKLGSKYILGIAGLFTVFSSFIFTSSVVNFLQSDISDLKDALFFFLLLIDLSKAGVLAQLALSSRSQEEVRANIARGMTLLGPSITLDTLVETLLIGIGTLSGVRRLEILCCFACLSVIVNYVIFMTFYPACLSLILELSRGSITIGQLSADKMLLMHSLHEEDQKPNPVVQRVKLIMSAGLILVHAHSRWPFKHEDCADVAEGTISQVNSYIVVNNHNDTEVPTDLHEYFMKWLSVSADHIVILILLLTLAIKFIFFEDKGELTEQLRLTEEREEQQRISEENMQ-------TTALD-VSLQQRFGAPLPVMHTPVFPI--------SGMNGEWVEVGDEMQVKFFDKEVQT------EKSIPHSQNFPESNTDNSQDTPETTRSVEECLAIYKSEL-GASALTDSEVIQLVQHKYIPAYQLEKAVGDMERGVNLRRTIVGRAGKFLDHLSDLPYKNYDYSKVLGSCCENVIGYIPIPVGIAGPLLVDGELIHVPMATTEGCLIASTNRGSRALLKCGVTSRVVADGMTRGPVVRFPNISRASEAMTWMQDEQNFATMKSSFDSTSRYARLTRIHIRIAGRLLFIRFVAKTGDAMGMNMLSKGTEKSLQAVQKIFTDMEILSLSGNFCTDKKPAAVNWVEGRGKSVVCEAIVPADIVTTVLKTSVHALVDVNISKNLIGSAIAGSIGGYNAHAANVVTAIYIATGQDPAQNVGSSNCMTIMEPWGPDGNDLYVSCTMPSIEIGTVGGGTGLPAQGACLGVLGAKGAHPETPGENASKVARVVCATVLAGELSLMAALTAGHLVKSHLRHNRSSTAM 883

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BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. nr
Match: gi|1069816721|ref|XP_018331654.1| (PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase [Agrilus planipennis])

HSP 1 Score: 724.546 bits (1869), Expect = 0.000e+0
Identity = 403/911 (44.24%), Postives = 568/911 (62.35%), Query Frame = 0

Query:   44 IFKSHGEFCASQPWEVIVTTFIFLICVLTVGSKHVMMVTEMDSSASSKIKPCLPSDPSCV--PEHHSRDWIETLVMAGFYCLAVLHITYRFKKIHLIRSNLIFNIALCYMTFASLLYALIIWSIGNPLKDNLHQAWFLIFLLVDMQKVTRMGQFALSSSHHRRISENVANGMYVLAPTFALDCLAKIFLVGLGSLTRIPQLEAFSWYAVVSVMVNFLVYLTFYPAGLSLVLELMYCTDGRPRWDVRQ--IINTLPGEDGQT-PVVHRVKVVATALLMIAHI---IFR-----------PPFLFSSASGISQPTTTLF-----SWATTNIEKVLITVVIVALSIKYLFYEDMDEAQELRKTYIEELTRKFAEDSEQEEFNRGNKVEMDRVSNSTDEGISIGSSAKPRPP--SCASRHGDDSSSESAWSEVGYLPDLKDQEAQTTDMASSEDEVDDDENGEKRRIRHHH---QLPKEPRSLEECTKIYKGTMDGVEYLIDEEVVHLVEKKVIRAHALESVLNNPTRGVEIRRKYVEKVAK--RDIGNLPFRNFDYDTVMGACCESVIGYMTMPVGVAGPLNLDGQLFYVPMATTEGCLVASVNRGCSALRTCGVTSRILADGMTRGPIVRFPNIAKMAEAKEWMEEPENFLQIKSNFDSTSRFARLQRLKLKPAGRELYIRFVAYTGDAMGMNMISKAAEFSLKQLIDVFPEMELVSLSGNMCTDKKPAAINWLDGRGKSVICEATVPGHIVETVLKTSPAALADLNRSKNLVGSAMAGSIGGFNAQAANVVTAVFIATGQDAAQNVASSNCLTQID---VVGDDLYMTCTMPSIEVGTVGGGTILTAQGACLDLLGVKGCQPASPGANAKQLASVVCATVLAGELSLMSALAAGHLVKSHLRHNRSNLAVGS 920
            +F  HGEFCA+ PWEVIV       C+ +V  ++          A+   KP +    SC+   E+++ D I   VM    CLAV +  Y+F  +    S  I  IA  +   +S ++   + ++      ++  A F   LL+D+ K   + QFAL + +   I  N+A GM +L PT  LD + +  ++ +G+L+ + +LE FS +A +S++VN+++++TFYPA LSL+LEL   +    + ++R   II+ L  ED ++ P+V RVK++ +  LM+ HI   ++R            PF+      ++   T  F      W   + + ++I ++++AL  K++F+E+ +E  E  + ++   + +F   +E +  N  N+    R                P  P     S   D+ S ++         DL D+E QT +    E E+        + +   +     P   RS+ EC  IYK  + G   L DEEV+ LV+ K I  + +E  +++P RGV IRR+ + K       + +LP++N+DY  VMGACCE+VIGYM +PVG+AGPL LDG++ YVPMATTEGCLVAS NRG  AL  CG+TSR++ADGMTRGP+VRFP++AK +E   WME  ENF +IK +FD++SRFARL++++++ AGR L+ RFVA TGDAMGMNM+SK  E SLK +  +FPEME++S+SGN C DKKPAA+NW++GRGKSV+CEA VP  IV TVLKTS  AL D+N SKN+VGSAMAGSIGGFNA AANVVTA+FIATGQD AQNV SSNC+T ++     G+DLY++CTMPS+EVGT+GGGT+L AQ ACL++LGVKG     PG NA QLA VVC TVLAGELSLM+ALAAGHLV+SHLRHNRS++A+ S
Sbjct:    5 LFYKHGEFCAAHPWEVIVAILTLTGCMFSVEQQY----------AAPLPKPPIRDCASCIQEAEYNAADLI---VMTLIRCLAVPYSYYQFCILQKFGSKYIIGIAGLFTVCSSFVFTTTVINLLRFDVADIRDALFFFILLMDLSKAVILAQFALCAKNQDEIKNNIAKGMAILGPTVTLDAIVEALVISVGALSGVRRLEIFSGFACLSILVNYVIFMTFYPACLSLLLELSRTSSIYLKKEIRPSLIISALNEEDNKSNPIVRRVKLIMSVGLMLVHIHRYMYRWPSHEESIDSVSPFVVEQHLALNSTQTVTFHGYLMRWIALSADHIVILILLLALLCKFIFFENKEELVEQLRVHMNNQSLEFLNPNEHQN-NHLNRTIRQRFI--------------PTMPFFRSHSMFLDNVSLDNEEK------DLVDKEVQTQN----EVEILSLPLNNSKEVTSKNIAVLCPPMARSVNECLTIYKSDL-GATTLTDEEVILLVKNKHIPPYQIEKAVDDPERGVRIRRQMIGKDGNFGEALEDLPYKNYDYTKVMGACCENVIGYMPIPVGIAGPLLLDGKVIYVPMATTEGCLVASTNRGSRALLKCGITSRVVADGMTRGPVVRFPSVAKASEVMVWMENKENFGKIKESFDASSRFARLKKIQVRIAGRYLFARFVATTGDAMGMNMLSKGTEMSLKFIQTLFPEMEILSISGNFCADKKPAAVNWIEGRGKSVVCEAVVPAEIVSTVLKTSTHALVDVNISKNMVGSAMAGSIGGFNAHAANVVTAIFIATGQDPAQNVGSSNCMTLMEPWGRNGEDLYISCTMPSVEVGTIGGGTVLPAQAACLEMLGVKGSHSECPGENANQLARVVCGTVLAGELSLMAALAAGHLVRSHLRHNRSSVAIFS 876

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BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. nr
Match: gi|1238870691|ref|XP_022249461.1| (3-hydroxy-3-methylglutaryl-coenzyme A reductase-like isoform X1 [Limulus polyphemus])

HSP 1 Score: 723.391 bits (1866), Expect = 0.000e+0
Identity = 401/929 (43.16%), Postives = 566/929 (60.93%), Query Frame = 0

Query:   33 SRSLPTLFIRKIFKSHGEFCASQPWEVIVTTFIFLICVLTVGSKHVMMVTEMDSSASSKIKPCLPSDPS--------CVPEHHSRDWIETLVMAGFYCLAVLHITYRFKKIHLIRSNLIFNIALCYMTFASLLYALIIWSIGNPLKDN---LHQAWFLIFLLVDMQKVTRMGQFALSSSHHRRISENVANGMYVLAPTFALDCLAKIFLVGLGSLTRIPQLEAFSWYAVVSVMVNFLVYLTFYPAGLSLVLELMY-CTDGRPRWDVRQIINTLPGEDGQ--TPVVHRVKVVATALLMIAHIIFRPPFL-----FSSASGISQPTTTLFS-------------WATTNIEKVLITVVIVALSIKYLFYEDMDEAQELRKTYIEELTRKFAEDSEQEEFNRGNKVEMDRVSNSTDEGISIGSSAK-----PRPPSCASRHGDDSSSESAWSEVGYLPDLKDQEAQTTDMASSEDEVDDDENGEKRRIRHHHQLPKEPRSLEECTKIYKGTMDGVEYLIDEEVVHLVEKKVIRAHALESVLNNPTRGVEIRRKYVEKVAK--RDIGNLPFRNFDYDTVMGACCESVIGYMTMPVGVAGPLNLDGQLFYVPMATTEGCLVASVNRGCSALRTCG-VTSRILADGMTRGPIVRFPNIAKMAEAKEWMEEPENFLQIKSNFDSTSRFARLQRLKLKPAGRELYIRFVAYTGDAMGMNMISKAAEFSLKQLIDVFPEMELVSLSGNMCTDKKPAAINWLDGRGKSVICEATVPGHIVETVLKTSPAALADLNRSKNLVGSAMAGSIGGFNAQAANVVTAVFIATGQDAAQNVASSNCLTQIDVV---GDDLYMTCTMPSIEVGTVGGGTILTAQGACLDLLGVKGCQPASPGANAKQLASVVCATVLAGELSLMSALAAGHLVKSHLRHNRSNLAV 918
            S++ P   + + F +HG FCAS PWEVIV       C+L++G K V                    DP+        C         ++ ++M    C AVL++ ++F+K++ + S  +  +A  +  F+S +++    S+ N L+ N   L++A     +L+D+ K   + QFALSSS    + EN+A GM +L P   LD + +  ++G+G+++ + ++E    +A +S +VN++V++TF+PA LSLVLEL     +GRP W +  +   L  E+ Q   PV+ RVKV+ +A L++ H+  R P +     F    G +     ++S             W   + E++++ V+  AL IKY+F+E+       R+   E+L    A     E FN  +    D   + T EG    SS       P   +   R       +  W       +++ +E    ++ + E    ++ N    R R       EPR+LEECT++   + +GV  L DEEV+ LVE KVI  + LESVLNNP RGV IRR+ + K +     +  LP+ N+DY  VMGACCE+VIGY+ +PVGVAGPL LD + +YVPMATTEGCLVAS NRGC AL   G V S I+A GMTRGP++R P+  +  E   W+++ EN+  +KS FDSTSRFARLQ++  + AGR L+IRF A TGDAMGMNM+SK  E SL +L  +FP +E++SLSGN CTDKKP+A+NW++GRGKSV+CEA +P  +V+ VLKTS   L D+N SKNL+GSA+AGS+GGFNAQAAN+VTA+FIATGQD AQNV SSNC+T ++     G++L+++CTMPSIE+GT+GGGT+L+ Q ACLDLLGV+G     PG NA  LASVVC TVLAGELSL+SALAAGHLV+SH+RHNRS L +
Sbjct:   14 SQTQPLTMLSQAFYNHGHFCASHPWEVIVAFLTLTACMLSMGPKLV--------------------DPNNKCGWNYQCHHNEGGNKGMDIVIMTITRCTAVLYVYHQFRKLYKLGSRYLLGVAALFTIFSSFVFST---SVVNFLEGNFSELNEALPFFLILIDLSKTGLLAQFALSSSTQEDVRENIAKGMRILGPKITLDTIVETLVIGVGTISGVKRMEEICCFACLSAVVNYIVFMTFFPACLSLVLELSREQEEGRPVWQLGHLTKVLQQEEEQKPNPVLQRVKVIMSAGLVLVHVQSRWPVVENDSVFDHHEGRAVGPERIYSSDNNSDFDPFLQRWFAVSPEQLVMLVLACALIIKYIFFEN-------REELQEQLAAAAASSRFNESFNNTSHCVTD--CSITKEGFQSNSSHPSVGPVPSLATLTKRISFVVGEDENW-------EVEKKEYMEKEIQTEESFFLEESNISSLRNR-------EPRTLEECTQLLN-SEEGVVQLTDEEVLMLVENKVIATYKLESVLNNPERGVHIRRQLIAKSSNYYEALEGLPYTNYDYSLVMGACCENVIGYVPVPVGVAGPLLLDNKTYYVPMATTEGCLVASTNRGCRALSLAGGVHSSIVASGMTRGPVIRLPSAQQAGEIMRWLDKEENYHVLKSAFDSTSRFARLQKISTRIAGRYLFIRFKAATGDAMGMNMVSKGTEVSLHKLQKIFPGIEVISLSGNYCTDKKPSAVNWIEGRGKSVVCEAEIPAKVVKNVLKTSVQTLIDVNISKNLIGSAVAGSVGGFNAQAANIVTAIFIATGQDPAQNVESSNCMTLMEPSGENGENLHISCTMPSIEIGTIGGGTVLSPQAACLDLLGVRGASAVDPGQNAATLASVVCGTVLAGELSLLSALAAGHLVRSHMRHNRSKLNI 895

[Close]

BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. nr
Match: gi|1059382575|ref|XP_017786105.1| (PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase-like [Nicrophorus vespilloides] >gi|1059382578|ref|XP_017786106.1| PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase-like [Nicrophorus vespilloides] >gi|1059382580|ref|XP_017786107.1| PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase-like [Nicrophorus vespilloides])

HSP 1 Score: 722.235 bits (1863), Expect = 0.000e+0
Identity = 409/904 (45.24%), Postives = 558/904 (61.73%), Query Frame = 0

Query:   43 KIFKSHGEFCASQPWEVIVTTFIFLICVLTVGSKHVMMVTEMDSSASSKIKPCLPSDPSCV-----PEHHSRDWIETLVMAGFYCLAVLHITYRFKKIHLIRSNLIFNIALCYMTFASLLYALIIWSIGNPLKDNLHQAWFLIFLLVDMQKVTRMGQFALSSSHHRRISENVANGMYVLAPTFALDCLAKIFLVGLGSLTRIPQLEAFSWYAVVSVMVNFLVYLTFYPAGLSLVLELMYCTDGRPRWDV-RQIINTLPGEDGQ--TPVVHRVKVVATALLMIAHI----IFR------PPFLFSSASGISQPTTTLF-----SWATTNIEKVLITVVIVALSIKYLFYEDMDEAQELRKTYIEELTRKFAEDSEQEEFNRGNKVEMDRVSNSTDEGISIGSSAKPRPPSCASRHGDDSSSESAWSEVGYLPDLKDQEAQTTDMASSEDEVDDDENGEKRRIRHHHQLPKEPRSLEECTKIYKGTMDGVEYLIDEEVVHLVEKKVIRAHALESVLNNPTRGVEIRRKYVEKVAK--RDIGNLPFRNFDYDTVMGACCESVIGYMTMPVGVAGPLNLDGQLFYVPMATTEGCLVASVNRGCSALRTCGVTSRILADGMTRGPIVRFPNIAKMAEAKEWMEEPENFLQIKSNFDSTSRFARLQRLKLKPAGRELYIRFVAYTGDAMGMNMISKAAEFSLKQLIDVFPEMELVSLSGNMCTDKKPAAINWLDGRGKSVICEATVPGHIVETVLKTSPAALADLNRSKNLVGSAMAGSIGGFNAQAANVVTAVFIATGQDAAQNVASSNCLTQIDVVGD---DLYMTCTMPSIEVGTVGGGTILTAQGACLDLLGVKGCQPASPGANAKQLASVVCATVLAGELSLMSALAAGHLVKSHLRHNRSNLAV 918
            ++F++HGEFCA+ PWEVIV T +  +C+LTV  +    + +             P+  SCV      E+++ D I   VM    CLAVL+  Y+F  +H + S  I  IA  +  F+S ++   + +        L  A F   LL+D+ K   + +FALS+S+   +  N+A GM VL PT  LD + +  ++G+G+L+ + +LE  S +A +SV+VN++V++TFYPA LSL+LEL   T+   + D+ R +I+    E+ Q   PV+ RVK++    LMI H      FR       P +      +++     F      W T + + ++I ++++AL++K++F+E+                        +EE   G ++    +    D    I ++A P P                     + P     + Q  + A  + EV  +   E   +    +  K  RSL EC  IY+  + G   L DEEV+ L+EKK I A+ +E  +++  RGV IRRK V       + + NLP++N+DY  VMGACCE+VIGY+ +PVGVAGPL LDG+  +VPMATTEGCLVAS NRG  AL  CGV SRI+ADGMTRGP+VRFP++   +EA  WME PEN+ QIK++FDS+SRFARL R+ ++  GR LYIRFVA TGDAMGMNM+SK  E +LK + D FPEME++SLSGN CTDKKPAA+NW++GRGKSV+CEA VP  IV+ VLKTS  AL D+N SKNL+GSA+AGSIGG+NA AANVVTA+FIATGQD AQNV SSNC+T ++  G    DLY+TCTMPSIE+GT+GGGTIL  Q +CL++LGVKG     PG NA QLA +VCATVLAGELSLM+AL AGHLV+SHLRHNRS+  V
Sbjct:    4 RLFRAHGEFCATHPWEVIVATLMLTVCMLTVEQQQHAPIPK-------------PTTRSCVGCLNEAEYNAADVI---VMTVIRCLAVLYSYYQFCNLHRLGSKYILGIAGLFTVFSSFVFTSTVLNFLRIDFSELKDALFFFLLLIDLSKAAMLAEFALSASNQNEVKSNIARGMSVLGPTITLDTIVETLVIGVGTLSGVHRLEMLSCFACLSVVVNYVVFMTFYPACLSLILELSRTTNLYGKRDIKRSLISRALNEEDQKSNPVLERVKIIMAIGLMIVHAHSWWPFRQEEDAISPLVVEQRMTLNRTDEAAFHGYIMKWVTLSADHIVILILLLALAVKFIFFEN------------------------KEELELGARL----IETKQDIPEIIMNAAAPMP--------------------FFKPKQFFLQNQDIEDAPQDKEVQTEPVAE---VAIKSEPSKPSRSLNECVSIYQSNL-GAAALNDEEVLLLIEKKYIPAYQVEKAVDDCERGVGIRRKMVGHKGNFTQALTNLPYKNYDYSKVMGACCENVIGYLPVPVGVAGPLFLDGKKIFVPMATTEGCLVASTNRGSRALLQCGVKSRIIADGMTRGPVVRFPSLDHASEAAAWMERPENYEQIKNSFDSSSRFARLMRIHIRLFGRSLYIRFVAKTGDAMGMNMLSKGTELALKFVRDRFPEMEILSLSGNFCTDKKPAAVNWIEGRGKSVVCEAIVPADIVQNVLKTSVDALVDVNISKNLIGSAVAGSIGGYNAHAANVVTAIFIATGQDPAQNVGSSNCMTLMEPWGKDGRDLYITCTMPSIEIGTIGGGTILPPQASCLEMLGVKGANSEFPGENASQLARIVCATVLAGELSLMAALTAGHLVQSHLRHNRSSTHV 839

[Close]

BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. nr
Match: gi|15824453|gb|AAL09351.1|AF304440_1 (3-hydroxy-3-methylglutaryl coenzyme A reductase [Ips pini])

HSP 1 Score: 722.235 bits (1863), Expect = 0.000e+0
Identity = 411/903 (45.51%), Postives = 560/903 (62.02%), Query Frame = 0

Query:   40 FIRKIFKSHGEFCASQPWEVIVTTFIFLICVLTVGSKHVMMVTEMDSSASSKIKPCLPSDPSCV--PEHHSRDWIETLVMAGFYCLAVLHITYRFKKIHLIRSNLIFNIALCYMTFASLLYALIIWSIGNPLKDNLHQAWFLIFLLVDMQKVTRMGQFALSSSHHRRISENVANGMYVLAPTFALDCLAKIFLVGLGSLTRIPQLEAFSWYAVVSVMVNFLVYLTFYPAGLSLVLELMYCTDGRPRWDVRQIINTLPGEDGQTPVVHRVKVVATALLMIAHIIFRPPFLFSSASGISQPTTTLFS--------------WATTNIEKVLITVVIVALSIKYLFYE--DMDEAQELRKTYIEELTRKFAEDSEQEEFN-----RGNKVEMDRVSNSTDEGISIGSSAKPRPPSCASRHGDDSSSESAWSEVGYLPDLKDQEAQTTDMASSEDEVDDDENGEKRRIRHHHQLPKEPRSLEECTKIYKGTMDGVEYLIDEEVVHLVEKKVIRAHALESVLNNPTRGVEIRRKYV--EKVAKRDIGNLPFRNFDYDTVMGACCESVIGYMTMPVGVAGPLNLDGQLFYVPMATTEGCLVASVNRGCSALRTCGVTSRILADGMTRGPIVRFPNIAKMAEAKEWMEEPENFLQIKSNFDSTSRFARLQRLKLKPAGRELYIRFVAYTGDAMGMNMISKAAEFSLKQLIDVFPEMELVSLSGNMCTDKKPAAINWLDGRGKSVICEATVPGHIVETVLKTSPAALADLNRSKNLVGSAMAGSIGGFNAQAANVVTAVFIATGQDAAQNVASSNCLTQID---VVGDDLYMTCTMPSIEVGTVGGGTILTAQGACLDLLGVKGCQPASPGANAKQLASVVCATVLAGELSLMSALAAGHLVKSHLRHNRS 914
             + ++F +HGEFC + PWEVIV T     C+ TV  ++ +  T          KP + S   C+   E+++ D I   ++     LAVL+  Y+F+K+H + S  I  IA  +  F+S ++   + ++      +L  A F   LL+D+ K   + QFAL+S +      N+A G+  L PT  LD + +  ++G+G+L+ + +LE  SW+A +SV+VN++V++ FYPA LSL+L+L   T+     D   I      E    PVV RVK++ +  LMI H+  R PF  S    I       F+              W     + ++I ++I AL IK LF+E  D+ E ++ ++T +E   R+  E++E+EE       R NK  M   S S D+             SC +   D    E   ++  Y PD           +S ED++                 PK  ++LE+C KIY     G   L DEE+V L++ + I  + +E  ++NP RGV IRRK +  +  A + +  LP+RN+DY  VMGACCE+VIGYM +PVG AGPL LDG+  YVPMATTEGCLVAS NRGC AL+  GVTSRI+ADGMTRGP+VRFP+I + ++A +W+++  NF  IK  FDS+SRFARLQR+ +K AGR L+IRFVA TGDAMGMNM+SK  E+SLK +   F +ME++SLSGN CTDKKPAA+NW++GRGKSV+CEA VP  IV  +LKT+  AL D+N SKN+VGSA+AGSIGGFNA AAN+VTA+F+ATGQD AQNV S NC+T ++     G+DLY++CTMPSIE+GT+GGGTIL  QG CL++LGV+G   A PGANA QLA +V ATVLAGELSLMSALAAGHLV+SHLRHNRS
Sbjct:    1 MVSRLFLAHGEFCINHPWEVIVATLTLTACMFTVERQNPIPPT----------KPIIKSCQGCIQEAEYNAADLISMTILRS---LAVLYCYYQFRKLHKLGSRYILGIAGLFTVFSSFIFTTTVLNLLRVEVSDLKDALFFFLLLIDLSKAGMLAQFALTSQNEIEGKNNIAKGLAELGPTITLDTVVETLVIGVGTLSGVERLEMLSWFACLSVLVNYVVFMAFYPACLSLILKLSRSTNFYKTKDPWMIFAFREEEHKSNPVVQRVKLIMSVGLMIVHVHSRWPFKDSEVYNIEPLVQQSFNNTEESSSVHGYFERWLALGADHIVILILITALLIKLLFFEIKDLTEIRD-QETQVEPEKREKGENTEKEEPKVVQEVRANK-RMPMFSLSEDD-------------SCETTFQD----EEVQTQTPYNPDAD---------SSPEDDI-----------------PKVCKTLEDCLKIYNNVDMGATALSDEEIVLLIKNRHIAGYQIEKAVDNPERGVGIRRKILGSDLDAPKVLEGLPYRNYDYSLVMGACCENVIGYMPIPVGFAGPLVLDGKEVYVPMATTEGCLVASTNRGCRALKEGGVTSRIVADGMTRGPVVRFPSIIRASQAMQWIQD--NFDGIKEQFDSSSRFARLQRVTMKIAGRLLFIRFVATTGDAMGMNMLSKGTEYSLKFVQRAFEDMEILSLSGNFCTDKKPAAVNWIEGRGKSVVCEAIVPAKIVANILKTNVHALVDVNNSKNMVGSAVAGSIGGFNAHAANIVTAIFLATGQDPAQNVGSCNCMTLMEPWGPTGEDLYISCTMPSIEIGTIGGGTILPPQGTCLEMLGVRGSNTAEPGANASQLAKIVGATVLAGELSLMSALAAGHLVRSHLRHNRS 843

The following BLAST results are available for this feature:

BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. L. salmonis genes
BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. SwissProt
BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. nr

BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. L. salmonis genes
Analysis Date: 2018-04-19 (T. kinsejongensis vs L. Salmonis peptides)
Total hits: 1


Match Name	E-value	Identity	Description
EMLSAG00000004979	0.000e+0	46.67	supercontig:LSalAtl2s:LSalAtl2s260:1508384:1510927...	[more]

BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. SwissProt
Analysis Date: 2018-04-19 (T. kingejongensis peptided Blastp vs. SwissProt)
Total hits: 25


Match Name	E-value	Identity	Description
gi\|391359371\|sp\|A7Z064.2\|HMDH_BOVIN	0.000e+0	41.35	RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme ...	[more]
gi\|2495262\|sp\|Q29512.1\|HMDH_RABIT	0.000e+0	42.36	RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme ...	[more]
gi\|118573790\|sp\|Q1W675.1\|HMDH_PIG	0.000e+0	41.41	RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme ...	[more]
gi\|123343\|sp\|P04035.1\|HMDH_HUMAN	0.000e+0	42.11	RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme ...	[more]
gi\|123344\|sp\|P09610.1\|HMDH_MESAU	0.000e+0	41.48	RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme ...	[more]
gi\|123347\|sp\|P20715.1\|HMDH_XENLA	0.000e+0	41.55	RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme ...	[more]
gi\|118573791\|sp\|P51639.2\|HMDH_RAT	0.000e+0	41.80	RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme ...	[more]
gi\|83305798\|sp\|Q5R6N3.1\|HMDH_PONAB	0.000e+0	42.00	RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme ...	[more]
gi\|123341\|sp\|P00347.1\|HMDH_CRIGR	0.000e+0	41.85	RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme ...	[more]
gi\|408360266\|sp\|Q01237.3\|HMDH_MOUSE	0.000e+0	42.00	RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme ...	[more]

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BLAST of 3-hydroxy-3-methylglutaryl- reductase vs. nr
Analysis Date: 2018-05-15 (T. kingsejongensis proteins Blastp vs. NR)
Total hits: 25


Match Name	E-value	Identity	Description
gi\|1279713396\|ref\|XP_022901116.1\|	0.000e+0	46.11	3-hydroxy-3-methylglutaryl-coenzyme A reductase-li...	[more]
gi\|451935537\|gb\|AGF87101.1\|	0.000e+0	44.18	3-hydroxy-3-methylglutaryl coenzyme A reductase [E...	[more]
gi\|9817458\|gb\|AAD20975.2\|	0.000e+0	45.43	3-hydroxy-3-methylglutaryl coenzyme A reductase [I...	[more]
gi\|751231033\|ref\|XP_011169052.1\|	0.000e+0	43.42	PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A r...	[more]
gi\|939255167\|ref\|XP_014247324.1\|	0.000e+0	45.23	3-hydroxy-3-methylglutaryl-coenzyme A reductase-li...	[more]
gi\|998503484\|ref\|XP_015511853.1\|	0.000e+0	44.70	PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A r...	[more]
gi\|1069816721\|ref\|XP_018331654.1\|	0.000e+0	44.24	PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A r...	[more]
gi\|1238870691\|ref\|XP_022249461.1\|	0.000e+0	43.16	3-hydroxy-3-methylglutaryl-coenzyme A reductase-li...	[more]
gi\|1059382575\|ref\|XP_017786105.1\|	0.000e+0	45.24	PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A r...	[more]
gi\|15824453\|gb\|AAL09351.1\|AF304440_1	0.000e+0	45.51	3-hydroxy-3-methylglutaryl coenzyme A reductase [I...	[more]

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Alignments

The following features are aligned


Aligned Feature	Feature Type	Alignment Location
scaffold208_size258758	supercontig	scaffold208_size258758:99540..102365 +

Analyses

This gene is derived from or has results from the following analyses


Analysis Name	Date Performed
maker	2018-02-12 .496401
T. kinsejongensis vs L. Salmonis peptides	2018-04-19
T. kingejongensis peptided Blastp vs. SwissProt	2018-04-19
T. kingsejongensis proteins Blastp vs. NR	2018-05-15

Properties


Property Name	Value
Note	C:integral to membrane

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Species	Type
snap_masked-scaffold208_size258758-processed-gene-1.0-mRNA-1	snap_masked-scaffold208_size258758-processed-gene-1.0-mRNA-1	Tigriopus kingsejongensis	mRNA

Sequences

The following sequences are available for this feature:

gene from alignment at scaffold208_size258758:99540..102365+

gene from alignment at scaffold208_size258758:99540..102365+

Legend: mRNA

Hold the cursor over a type above to highlight its positions in the sequence below.

>snap_masked-scaffold208_size258758-processed-gene-1.0 ID=snap_masked-scaffold208_size258758-processed-gene-1.0|Name=3-hydroxy-3-methylglutaryl- reductase|organism=Tigriopus kingsejongensis|type=gene|length=2826bp|location=Sequence derived from alignment at scaffold208_size258758:99540..102365+ (Tigriopus kingsejongensis)
ATGGAGGTTCAAGCTCCCCTGAAACCCTCAAAAGTGGCAATTGCGGCCAC
AAACAGCACTTCTTCTTCGGATCGCCACACACCGGAGGAACAACAATCAC
GAAGCCTCCCAACCCTCTTTATTCGAAAGATCTTTAAATCTCACGGGGAA
TTCTGTGCTAGCCAACCGTGGGAAGTGATTGTGACCACTTTCATCTTTCT
GATTTGCGTCCTCACCGTTGGGAGCAAGCACGTCATGATGGTGACGGAAA
TGGATTCATCCGCGAGTTCCAAGATCAAGCCTTGCCTTCCAAGCGACCCT
TCCTGTGTACCGGAGCATCACTCCAGGGATTGGATTGAAACTTTGGTCAT
GGCTGGCTTCTATTGCCTGGCAGTTCTGCACATTACCTATCGCTTCAAGA
AGATCCATCTGATCCGCTCCAACTTGATCTTCAACATCGCCTTGTGCTAT
ATGACCTTTGCATCGCTGCTTTACGCCCTGATCATCTGGAGCATTGGAAA
CCCTCTAAAGGATAATCTCCACCAGGCTTGGTTCCTGATTTTCCTCCTGG
TTGACATGCAGAAAGTGACCCGGATGGGACAATTTGCCCTGAGCTCATCG
CACCATCGCCGAATTAGCGAGAACGTGGCTAATGGCATGTATGTCTTGGC
TCCCACCTTTGCATTGGATTGCTTGGCTAAGATCTTTCTGGTTGGATTAG
GATCGCTGACAAGAATACCCCAACTGGAGGCCTTCTCTTGGTATGCCGTT
GTCTCAGTCATGGTAAATTTCTTGGTTTACTTGACCTTCTACCCCGCTGG
CTTATCTCTGGTCCTGGAACTCATGTACTGCACGGATGGAAGACCACGAT
GGGACGTGCGACAGATAATCAACACCCTGCCCGGGGAGGACGGCCAGACC
CCTGTGGTGCACCGGGTCAAAGTGGTAGCCACGGCTCTTCTGATGATCGC
CCATATAATCTTCCGCCCTCCATTCTTATTCAGCAGTGCGAGTGGAATCT
CCCAGCCCACAACAACCCTATTCTCTTGGGCCACCACCAACATCGAGAAA
GTTCTCATTACTGTGGTGATTGTGGCACTGTCGATCAAGTACCTCTTCTA
CGAGGATATGGACGAGGCTCAAGAGCTGAGAAAAACCTACATCGAGGAGC
TCACACGAAAATTTGCAGAGGACAGTGAACAAGAAGAATTCAACCGCGGC
AACAAAGTCGAGATGGACAGGGTTTCCAATTCCACTGATGAAGGAATCAG
CATTGGCAGCTCGGCGAAACCTCGCCCCCCGTCCTGTGCCTCTCGACATG
GAGACGATTCGAGTAGCGAGTCTGCTTGGTCGGAGGTTGGTTACTTACCT
GATCTCAAAGACCAAGAAGCTCAAACCACTGACATGGCATCATCTGAAGA
TGAGGTCGACGATGACGAAAATGGCGAGAAAAGACGTATTCGACACCACC
ATCAACTTCCCAAGGAGCCGCGGAGCTTGGAGGAATGCACAAAGATCTAC
AAAGGGACCATGGACGGTGTGGAATATCTCATCGATGAAGAAGTGGTTCA
TTTGGTCGAGAAGAAAGTGATACGTGCTCATGCCCTGGAGAGTGTCTTGA
ACAATCCCACCCGAGGTGTGGAGATCCGACGCAAATACGTCGAGAAAGTG
GCCAAGAGAGACATTGGAAACCTCCCTTTTAGAAACTTTGACTACGACAC
TGTGATGGGTGCCTGTTGCGAGAGTGTAATAGGCTACATGACCATGCCTG
TTGGGGTCGCGGGACCCTTGAACTTGGATGGCCAATTGTTCTATGTTCCT
ATGGCAACCACGGAAGGATGCCTGGTGGCGAGCGTAAACCGTGGCTGTAG
TGCATTGAGAACATGCGGGGTGACAAGCCGCATCCTCGCCGACGGAATGA
CTCGGGGCCCCATCGTTCGCTTCCCCAACATTGCAAAAATGGCCGAGGCC
AAGGAGTGGATGGAGGAGCCCGAAAACTTCCTACAAATCAAAAGTAACTT
CGACAGTACAAGTCGGTTTGCAAGACTCCAAAGACTAAAACTTAAGCCTG
CAGGACGTGAGCTCTACATTCGCTTCGTGGCCTACACGGGTGATGCCATG
GGTATGAACATGATTTCCAAAGCCGCAGAATTTTCGCTCAAGCAGTTGAT
AGATGTCTTCCCCGAGATGGAATTAGTCAGCCTAAGTGGAAACATGTGCA
CCGATAAGAAGCCAGCAGCCATCAATTGGTTGGACGGCAGAGGAAAATCA
GTCATTTGCGAGGCCACAGTTCCGGGGCACATTGTCGAGACGGTTCTCAA
GACCTCCCCTGCCGCTCTCGCAGATCTCAACAGATCCAAAAACTTGGTTG
GTTCGGCCATGGCCGGCAGCATTGGAGGCTTCAACGCCCAAGCCGCCAAC
GTGGTGACGGCCGTGTTTATCGCCACAGGGCAGGACGCAGCTCAAAACGT
GGCCAGCAGCAACTGCCTCACCCAGATCGATGTGGTGGGTGACGACCTCT
ACATGACTTGCACAATGCCTTCCATTGAGGTTGGTACCGTGGGAGGTGGA
ACTATACTGACGGCTCAGGGGGCCTGCCTCGATCTGCTTGGCGTCAAGGG
ATGTCAACCCGCCTCCCCTGGCGCTAATGCAAAGCAACTGGCCAGTGTGG
TATGTGCCACTGTCTTAGCCGGAGAGCTCTCCTTAATGTCAGCCCTCGCA
GCTGGCCATCTGGTGAAAAGCCACCTGAGGCACAACCGATCAAATCTCGC
AGTGGGCTCTGTTGCGGGTCCAGAATCCATGGCCAAACCCATGCTCTGTA
TTCATCCCAATGCCTCCGTGCCCTAG

Synonyms

The feature '3-hydroxy-3-methylglutaryl- reductase' has the following synonyms


Synonym
Tk04201

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