endoprotease furin, snap_masked-scaffold298_size217389-processed-gene-0.1 (gene) Tigriopus kingsejongensis
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Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of endoprotease furin vs. L. salmonis genes
Match: EMLSAG00000000132 (supercontig:LSalAtl2s:LSalAtl2s1021:129587:131575:1 gene:EMLSAG00000000132 transcript:EMLSAT00000000132 description:"augustus_masked-LSalAtl2s1021-processed-gene-0.9") HSP 1 Score: 783.482 bits (2022), Expect = 0.000e+0 Identity = 382/603 (63.35%), Postives = 447/603 (74.13%), Query Frame = 0
Query: 20 YHNHFALHIPEGEAKANRIALNLGFKNRGPIGTLSNHFLFEHEFLRPRCTNHSLEHHEILIKEPGVHWFEQQHERRRFKRDLS-------------------------------DSMYISDPLFKDQWFLNHGAFDGSDMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMPQDNSDNKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDGLVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSISSASQGGKKPWYLEECSSTLASTYSSGTPGHDASIATVDQDARLRPDKICTTSHTGTSASAPIAAGVCALALEANPNLTWRDMQHIVVITSNPAPLLRESGWRVNAVGRKYSHKFGYGLMDASAMVEVAKVWPGSGRQAICETDTLSLDLPIPVNSGSVARVTLKTDACSGTKKEIRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSLLLPRPRDMTNGGFEDWPFLSVHFWGEPANGTWTLEV-NHSPSVKSTSGLAKGIVKKWKMLFYGTRKSPLR 590
Y N FA++IP+G+ A+ +A GF+N G IGTL N+FLF+H + R T+ + H L P V WFEQQ E++R KRD + +DP+F QW LN GA +G DMNV+PAW +GY+G VVVTILDDGIQ +HPD NYDPLASTDIN ND DPMPQDN +NKHGTRCAGEVAA A NG+CGVGIAYNASIGGVRMLDG+VNDAVEARALSLNP+H+DIYSASWGPEDDGKTVDGPGPLAK+AF+NGV GR GKGSIFVWASGNGGR DNCNCDGYTNSIFTLSISSA+QGG KPWYLEECSSTLA+TYSSGTPG D SI+TVDQDARLR + +CT+ HTGTSASAPIAA VCALALEANP+LTWRDMQ++VV+TS PL ESGW +N GR YSH+FGYGLMDA MV A W +Q IC+T + ++ IP + G AR +++TD CSGT + YLEHVQCKISL Y+PRG L I+LTSPSGTKS+LL PRP+D F+DWPFLSVHF+GE GTW LEV N S SG +G++KKW+++FYGT +P+R
Sbjct: 25 YQNQFAVYIPKGKVVADTLAQEYGFENIGQIGTLDNYFLFKHSRINKRSTDAATLHAIFLTLNPEVKWFEQQKEKKRVKRDFNVWSPVFDSQSTGTTLTSSSIGKRQGFRFVXEPRNLFADPIFTYQWHLNAGARNGFDMNVKPAWKRGYSGTGVVVTILDDGIQMNHPDXISNYDPLASTDINDNDADPMPQDNGNNKHGTRCAGEVAASANNGVCGVGIAYNASIGGVRMLDGVVNDAVEARALSLNPDHVDIYSASWGPEDDGKTVDGPGPLAKRAFLNGVVRGRQGKGSIFVWASGNGGRHSDNCNCDGYTNSIFTLSISSATQGGYKPWYLEECSSTLATTYSSGTPGRDGSISTVDQDARLRSEYLCTSEHTGTSASAPIAAAVCALALEANPSLTWRDMQYLVVMTSRSNPLKDESGWAINGAGRSYSHQFGYGLMDADHMVRAAVGWKALPQQHICQTPIMVPNIQIPDSYGIPARASIQTDGCSGTINSVNYLEHVQCKISLKYYPRGNLMIMLTSPSGTKSTLLFPRPKDNFATSFQDWPFLSVHFYGEIVPGTWKLEVLNMGSSAPLRSG--QGLLKKWQLIFYGTENNPIR 625
BLAST of endoprotease furin vs. L. salmonis genes
Match: EMLSAG00000012868 (supercontig:LSalAtl2s:LSalAtl2s97:2839025:2843929:-1 gene:EMLSAG00000012868 transcript:EMLSAT00000012868 description:"augustus_masked-LSalAtl2s97-processed-gene-28.2") HSP 1 Score: 744.577 bits (1921), Expect = 0.000e+0 Identity = 480/1203 (39.90%), Postives = 606/1203 (50.37%), Query Frame = 0
Query: 15 GHGKIYHNHFALHIPEGEAKANRIALNLGFKNRGPIGTLSNHFLFEHEFLRPRCTNHSLEHHE--ILIKEPGVHWFEQQHERRRFKRD----LSDSMYI-SDPLFKDQWFLNHGAFDGSDMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMPQDNSDNKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDGLVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSISSASQGGKKPWYLEECSSTLASTYSSGTPGHDASIATVDQDARLRPDKICTTSHTGTSASAPIAAGVCALALEANPNLTWRDMQHIVVITSNPAPLLRESGWRVNAVGRKYSHKFGYGLMDASAMVEVAKVWPGSGRQAICETDTLSLDLPIPVNSGSVARVTLKTDACSGTKKEIRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSLLLPRPRDMTNGGFEDWPFLSVHFWGEPANGTWTLEVNHSPSVKSTSGLAK-GIVKKWKMLFYGTRKSPLRQSQLVSEFGPLPSEDFGDGLPGKMMDGSPEDGHNVSPNNN--GQHVSWSSGSFSTRAHSGGILEHNKGQSGLLDYESPSSSCHPQCEGNRCSGPKSTECYSCQNFKFGNVCVEHCPLTTYVSLRGTCQACHSSCQTCSGPNPNQCLTCSKSLFLLSDQSRCIKDQCPSGYRQRPSLNECVPCPYHCESCTETSEGVVNLIEGPRSGSLGIGETTLVCLKCQKGLVRSVLENKCLNGCPFGFSLNPETRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCS-NDQKCIKCQAGWSFANEK-EACSPQANAQCPEGSF---KTRSCDPCHESCATCTGNLSTQCSLC-LDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFSKALGGLCAPCGSTCNTCFD-KADNCLSCPKNHVLDLSSCLDHECPNGTFYDTQLNECRHCPHNCMTC--ESVSSCSQCGLDHFLTGSGKCSANCQGNEYQTPNGLCLACNRSCEACMGPHSNECLSCRVGKYLSTTGECLEECLHGFVDKNSQCQACHSSCLACTGPSL 1198
G YHN FAL IP G+ RI GPI L+++ LFE + R SLE HE ++ + W+EQQ E+ R KRD +D+++ SDPLF+ QWFLN GA DGSDMNV AW G TGK VVVTILDDGIQT+HPDL NYDPLASTDIN ND++PMPQD+ DNKHGTRCAGEVAA AFN CGVG+AYNASIGGVRMLDG+VNDAVEARALSL PNHI IYSASWGPEDDGKTVDGPG L K+AFI+G+ GR G+GSIFVWASGNGGR+ DNCNCDGYTNSI+TLSISSA+QGG KPWYLEECSSTLASTYSSGTP HDASI TVDQD + + G S G+ L W+ L+ + + K++P + S+ V + K + +LEHVQ IS+ PRG+L +VL SPSGT+S LL+ R +D +G FEDWPFLSVHFWGE G WTLEV ++ + K G++K W+++FYG +PLR NV NN+ G+ V E+ + + E +S C S +C C++F F N CVE+CP T+ + +G C+ CH C TC GP NQCLTC+ L + S C K CP + N C+PC ++ ++C L +TT C+ C G + E+ C CP GF + + C CH C C G +QC C DG FY E C+ CP+ + + +EC PC +GC C + +KC KC+ W K P CP GS+ K C CH C C G C C D F+ C+ CP+ Y +C CP C +C+ ++C C +G ++ A+CP+G F C PC C +C K + C+SC + V CP+G F Q ECR C C TC + +C C GS C A G Y CL C+ SC C G +NECLSC + + E+C D+N C+ C+ S C P+L
Sbjct: 19 GREVYYHNQFALRIPSGDPY--RIGQRHDLNYIGPI--LNDYHLFEVHHIHRR----SLEPHEDHQFHEDEDITWYEQQIEKNRIKRDNDVERTDTIFQPSDPLFERQWFLNQGAHDGSDMNVVEAWKLGITGKGVVVTILDDGIQTNHPDLIDNYDPLASTDINDNDDNPMPQDDGDNKHGTRCAGEVAAIAFNDYCGVGVAYNASIGGVRMLDGVVNDAVEARALSLRPNHIHIYSASWGPEDDGKTVDGPGRLTKEAFISGILKGRSGRGSIFVWASGNGGRRDDNCNCDGYTNSIYTLSISSATQGGYKPWYLEECSSTLASTYSSGTPSHDASITTVDQDG----ESGWYVNGVGKHYSHKFGYGLMDAGTMVKSALNWK-------------------------------------LVGPQMVYKSEKIYPNK-----------------TLRKESLGEVVYAFIYIKESNKLMNHLEHVQAVISITGSPRGSLELVLISPSGTRSILLMKRSKDTRDGSFEDWPFLSVHFWGETPTGKWTLEVIRHEDIQPENNNRKDGVLKDWQLIFYGVEGNPLRD--------------------------------NVRANNSNLGEQVE-------------SYDEYEGLSNDTVGVEVSTSDC-----------DNSEKCLKCKSFIFNNNCVENCPNKTFPA-QGYCKPCHFKCNTCYGPQLNQCLTCTVPYLFLPESSSCHK-VCPXSHFLEKDYNICLPC-FNFKNC------------------LQCHQTTGNCILCNTGFFVTP-ESYCSPYCPSGFYSDSKENQCSTCHTVCEECFGPKQSQCISCKDGKFYHERTCLEKCPSSHYENKDLKECTPCSKGCLECPLHPRKCQKCEENWILLGNKCFPAIPNKKTSCPMGSYYDLKKLECSSCHYQCQNCFGRGPDHCITCNKDNPFHHISSCLHTCPS-YFTYPEGLQCNHCPHSCRSCTGAKQCNLCNSGSVLTSDGRCV-----AKCPQGYFPSIESLKCEPCHRNCKSCIGIKENECISCVDSFVHAPDGSCRSTCPDGFF--LQEGECRPCHGRCKTCFGQENDNCLSCFKGLLFEGS-TCWACKSGEYYDDIAAKCLKCHLSCRQCFGDLANECLSCNNHRAFNKWNNTCEKCC--MTDENDCCE-CNKSKTICVNPNL 1065 HSP 2 Score: 258.84 bits (660), Expect = 3.762e-70 Identity = 188/609 (30.87%), Postives = 272/609 (44.66%), Query Frame = 0
Query: 805 CLKCQKGLVRSVLENKCLNGCPFGFSLNPETRSCDPCHESCATCTGNLSTQCSLCLDGTFYF--EHKCVPDCPAGYRPDVHHQECVPCP--QGCHTCSNDQ-KCIKCQAGWSFANEKEACSPQANAQCPEGSF---KTRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCS-NDQKCIKCQAGWSFANEK-EACSPQANAQCPEGSFSKALGGLCAPCGSTCNTCFDKA-DNCLSCPKNHVLD-LSSCLDHECPNGTFYDTQLNECRHCPHNCMTCESVSSCSQCGLDHFLTGSGKCSANCQGNEYQTPNGL-CLACNRSCEACMGPHSNECLSCRVGKYLSTTGECLEECLHGFVDKNSQCQACHSSCLACTGPSLFQCSTCPSGTKLGPQANCLSCEPRKFHDAHSDECLACHESCGTCSGPQDNHCLSCSLPLVLDTWNTTCVPCCESSDEKHCCSCTPSRDKCLQPSKKMLSRKRSSVRFG----LGDEALTNPSRSLFHYGSLLAILALMTLVIVKYFKRAKIRLYAMNGSRARRHHQRRRQTSQD-LSGTNYQKLLKDEQPADGPLNFNRNAR 1395
CLKC+ + N C+ CP P C PCH C TC G QC C + C CP + + + C+PC + C C CI C G+ F + CSP CP G + K C CH C C G +QC C DG FY E C+ CP+ + + +EC PC +GC C + +KC KC+ W K P CP GS+ C+ C C CF + D+C++C K++ +SSCL H CP+ Y L +C HCPH+C +C C+ C LT G+C A C + + L C C+R+C++C+G NEC+SC + G C C GF + +C+ CH C C G C +C G L + C +C+ +++D + +CL CH SC C G N CLSC+ + WN TC CC +DE CC C S+ C+ P+ SRKRSS G L + + +F+ + ++ +V+V + +R + + SR H+Q + + D +S Y +E P ++ N R
Sbjct: 579 CLKCKS----FIFNNNCVENCPN--KTFPAQGYCKPCHFKCNTCYGPQLNQCLTCTVPYLFLPESSSCHKVCPXSHFLEKDYNICLPCFNFKNCLQCHQTTGNCILCNTGF-FVTPESYCSPY----CPSGFYSDSKENQCSTCHTVCEECFGPKQSQCISCKDGKFYHERTCLEKCPSSHYENKDLKECTPCSKGCLECPLHPRKCQKCEENWILLGNKCFPAIPNKKTSCPMGSYYDLKKLECSSCHYQCQNCFGRGPDHCITCNKDNPFHHISSCL-HTCPSYFTYPEGL-QCNHCPHSCRSCTGAKQCNLCNSGSVLTSDGRCVAKCPQGYFPSIESLKCEPCHRNCKSCIGIKENECISCVDSFVHAPDGSCRSTCPDGFFLQEGECRPCHGRCKTCFGQENDNCLSCFKGL-LFEGSTCWACKSGEYYDDIAAKCLKCHLSCRQCFGDLANECLSCNNHRAFNKWNNTCEKCC-MTDENDCCECNKSKTICVNPNLNN-SRKRSSYTIGRSYQLNNNQMKRNESGIFY---IFTASTILFVVLVYFIRRNRYKC----RSRFYNHYQGYTKVAYDNISDHVYLSNESNENRFIRPALYDFNQR 1164 HSP 3 Score: 127.487 bits (319), Expect = 1.222e-29 Identity = 108/379 (28.50%), Postives = 159/379 (41.95%), Query Frame = 0
Query: 897 CSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFKTRS-CDPCHESCATCTGNLSTQCSLCLDGTFYF--EHKCVPDCPAGYRPDVHHQECVPC--PQGCHTCSNDQ-KCIKCQAGWSFANEKEACSPQANAQCPEGSFSKALGGLCAPCGSTCNTCFD-KADNCLSCPKNHVLDLSSCLDHECPNGTFYDTQLNECRHCPHNCMTCE-SVSSCSQCGLDHFLTGS-------GKCSANCQGNEYQTPNGLCLACNRSCEACMGPHSNECLSCRVGKYLSTTGECLEECLHGFV-DKNSQCQACHSSCLACTGPSLFQCSTCPSGTKLGPQANCLS-CEPRKFHDAHSDECLACHESCGTCSGPQDNHCLSCSLPLV 1258
C N +KC+KC++ + F N CP +F + C PCH C TC G QC C + C CP + + + C+PC + C C CI C G+ F + CSP CP G +S + C+ C + C CF K C+SC +CL+ +CP+ + + L EC C C+ C C +C + L G+ K ++ G+ Y C +C+ C+ C G + C++C CL C F + QC C SC +CTG QC+ C SG+ L C++ C F S +C CH +C +C G ++N C+SC V
Sbjct: 573 CDNSEKCLKCKS-FIFNN-------NCVENCPNKTFPAQGYCKPCHFKCNTCYGPQLNQCLTCTVPYLFLPESSSCHKVCPXSHFLEKDYNICLPCFNFKNCLQCHQTTGNCILCNTGF-FVTPESYCSP----YCPSGFYSDSKENQCSTCHTVCEECFGPKQSQCISCKDGKFYHERTCLE-KCPSSHYENKDLKECTPCSKGCLECPLHPRKCQKCEENWILLGNKCFPAIPNKKTSCPMGSYYDLKKLECSSCHYQCQNCFGRGPDHCITCNKDNPFHHISSCLHTCPSYFTYPEGLQCNHCPHSCRSCTGAK--QCNLCNSGSVLTSDGRCVAKCPQGYFPSIESLKCEPCHRNCKSCIGIKENECISCVDSFV 935
BLAST of endoprotease furin vs. L. salmonis genes
Match: EMLSAG00000007470 (supercontig:LSalAtl2s:LSalAtl2s427:85085:93720:1 gene:EMLSAG00000007470 transcript:EMLSAT00000007470 description:"maker-LSalAtl2s427-augustus-gene-1.11") HSP 1 Score: 468.003 bits (1203), Expect = 2.300e-148 Identity = 251/497 (50.50%), Postives = 321/497 (64.59%), Query Frame = 0
Query: 108 SDPLFKDQWFLNHGAFDGSDMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMPQDN--SDNKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDGLVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSISSASQGGKKPWYLEECSSTLASTYSSGTPGHDASIATVDQDARLRPDKI--------CTTSHTGTSASAPIAAGVCALALEANPNLTWRDMQHIVVITS--NPAPLLRESGWRVNAVGRKYSHKFGYGLMDASAMVEVAKVWPGSGRQAICETDTLSLDLPIPVNSGSVARVTLKTDACSGTKKEIRYLEHVQCKISLH-YHPRGALHIVLTSPSGTKSSLLLPRPRDMTNGG---FEDWPFLSVHFWGEPANGT----WTLEVNHSPSVKSTSGLAKGIVKKWKMLFYGT 584
+D + + W+LN G D DMNV+ AW GY+GK VVTILDDG++ DHPDL NYD AS D+N D DP P+ + + NKHGTRCAG++AA A N C VGIA+NA +GG+R+LDG + D++EA+ALS N ++IDIYSASWGP+D G TVDGPG LAK+A +G+KFGR GKGSIFVWASGNGG+K D+CNCDGY+ SIFTLS+SS S+ G PWY E C+S+LA+TYSSG + RLR KI CT SHTGTSAS+P+A + AL LEANPN+TWRD+QHIVV+T+ + L+ W VN GR++SH +G+GLMDA AMV++A W Q IC + + + + S CS +EI+ LEH+ I L RG L + LTSPSGT S LL RP D G F +WP +SVHFWGE WTL+V + +G+A +K+WK+ FYG+
Sbjct: 246 NDRFWPEMWYLNRGG-DHLDMNVEEAWEGGYSGKGXVVTILDDGVEWDHPDLIDNYDENASADLNDRDGDPYPRYDIINSNKHGTRCAGQIAAAANNSYCSVGIAFNAKVGGIRILDGRIFDSLEAQALSYNRDYIDIYSASWGPDDXGATVDGPGVLAKQALEDGIKFGRKGKGSIFVWASGNGGKKSDDCNCDGYSTSIFTLSVSSTSENGFIPWYSESCASSLATTYSSGA-----------SNRRLREKKIVTTDLHGSCTKSHTGTSASSPMAXALIALTLEANPNMTWRDVQHIVVLTARGSAGSYLKSDDWSVNGAGREFSHSYGFGLMDADAMVKLAANWTNIPEQMICHSSEVIYENGLVGEQDSEIESKTNASLCS---EEIKSLEHIHLFIDLDSTSRRGDLSVSLTSPSGTTSRLLNFRPFDDERVGFASFNNWPMMSVHFWGENITNKDLDEWTLKV-----INRGNGVAS--LKRWKLRFYGS 720
BLAST of endoprotease furin vs. L. salmonis genes
Match: EMLSAG00000011906 (supercontig:LSalAtl2s:LSalAtl2s83:633334:637253:1 gene:EMLSAG00000011906 transcript:EMLSAT00000011906 description:"maker-LSalAtl2s83-augustus-gene-6.18") HSP 1 Score: 393.66 bits (1010), Expect = 1.608e-120 Identity = 252/622 (40.51%), Postives = 335/622 (53.86%), Query Frame = 0
Query: 35 ANRIALNLGFKNRGPIGTLSNHFLFEHEFLRPRCTNHSLEHHEILIKEPGV-HWFEQQHERRRFKRDLSDSMYI----------SDP---------------LFKDQ---------WF--LNHGAFDGS------------------------DMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMPQDNSD--NKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDG-LVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSISSASQGGKKPWYLEECSSTLASTYSSGTPGHDASIATVDQDARLRPDKICTTSHTGTSASAPIAAGVCALALEANPNLTWRDMQHIVVITSNPAPLLRESG---WRVNAVGRKYSHKFGYGLMDASAMVEVAKVWPGSGRQAICETDTLSLDLPIPVNSGSVARVTLKTDACSGTKKEIRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSLLLPRPRDMT-NGGFEDWPFLSVHFWGEPANGTWTLEVNHSPSVKSTSGLAKGIVKKWKMLFYGTRKSP 588
A+ IA GF N G I N + F + L T S+ H L +P V H F+Q +R + LS SM I +DP L KDQ ++ L H GS D+NVQ AWA+G TGK V I+DDG L + AS D + ND P P+ D N HGTRCAGEV+ NGICGVG+AY++ + G+RMLD + D +EA ++ PN IDIYSASWGP DDG+TVDGP +A + GV GR+GKG+I+VWASG+GG + D+CNCDGY S++T+SI+SA G+ Y E CSSTLAST+S+G + +AT D + CT +G SA+AP AAGV ALALEAN LTWRDMQH+ V+TS L G W +N VG +++H FG+G++DA AMV +AK W + C+ + IP S S+ +T++TDAC+G E+ YLEHVQ I+++ RG + + L SP GT+S +L RP D GF WPF++ H W E G WTLE L +G +K+W ++ +GTR +P
Sbjct: 118 AHNIARRNGFVNVGTILGSPNEYHFVNHALPQARTKRSVPHIRKLKADPLVEHAFQQSGFKRDKRYGLSRSMRIQNQKQKPRNVNDPWPYLRQALDKPQKRALSKDQDSNVIHDENFYNRLQHSKSTGSKRGYNPLRVENLKNDGQNGGKPKLDLNVQAAWAQGVTGKNVTTAIMDDGTT-----LFLVNNARASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSGARDNGICGVGVAYDSMVAGIRMLDQPYMTDLIEANSMGHEPNLIDIYSASWGPTDDGRTVDGPRNATMRAIVRGVNEGRNGKGNIYVWASGDGGEE-DDCNCDGYAASMWTISINSAINTGENAHYDESCSSTLASTFSNGAKDPNTGVATTDLYGK------CTRXXSGXSAAAPEAAGVFALALEANRQLTWRDMQHLTVLTSKRNSLFDSKGRFHWTMNGVGLEFNHLFGFGVLDAGAMVALAKQWKTVPARYHCQAGSDKTVREIP-GSKSLF-LTIETDACAGKDTEVNYLEHVQAVITVNSTRRGDVELFLRSPMGTRSMILSNRPNDDDGQDGFTKWPFMTSHTWAEYPRGKWTLEARF-----HGERLNRGFLKEWTLMLHGTRDAP 720
BLAST of endoprotease furin vs. L. salmonis genes
Match: EMLSAG00000007363 (supercontig:LSalAtl2s:LSalAtl2s418:9796:10997:-1 gene:EMLSAG00000007363 transcript:EMLSAT00000007363 description:"maker-LSalAtl2s418-augustus-gene-0.2") HSP 1 Score: 335.495 bits (859), Expect = 4.311e-104 Identity = 177/334 (52.99%), Postives = 223/334 (66.77%), Query Frame = 0
Query: 18 KIYHNHFALHIPEGEAKANRIALNLGFKNRGPIGTLSNHFLFEHEFLR---PRCTNHS--LEHHEILIKEPGVHWFEQQHERRRFKRDLSD---------SMYISDPLFKDQWFLNHGAFDGSDMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMPQDN--SDNKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDGLVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSISSASQGGKKPWYLEECSSTLASTY 335
KIY N + LH+P+G A +A G + + N ++ + +R R + L +I+ ++ V W EQ R KR+ S S ++DP + W+LN D +MNV+ AW +G TGK V TILDDGI+ +HPDL RNYDPLASTDIN ND DP P+ + + N+HGTRCAG+VAA N +C VGIAYNA IGG+RMLDG V+DAVEAR+LS NP+H+DIYS+SWGP DDGKTVDGPG LA +AF NGV GR GKGSIFVWASGNGGR DNCNCDGY SI+T+++SS S+ G+ PWY E C+STLA+TY
Sbjct: 44 KIYLNEWTLHLPKGLESAITLASKRNLILLGEV--IPNSHIYHFQSVRRGHKRSKRQASWLSRRKIM-QDKSVTWGEQCTVVSRVKREGSKNQRRRHQHFSYEMNDPYWHKMWYLNRE--DDLNMNVEGAWEQGVTGKGVAXTILDDGIEKBHPDLLRNYDPLASTDINDNDSDPNPRYDFSNSNRHGTRCAGQVAASPNNSLCAVGIAYNAQIGGIRMLDGQVSDAVEARSLSFNPDHVDIYSSSWGPNDDGKTVDGPGKLAHRAFHNGVTRGRSGKGSIFVWASGNGGRFKDNCNCDGYATSIYTITVSSTSESGRIPWYSEACASTLATTY 372
BLAST of endoprotease furin vs. L. salmonis genes
Match: EMLSAG00000007238 (supercontig:LSalAtl2s:LSalAtl2s406:251464:253084:1 gene:EMLSAG00000007238 transcript:EMLSAT00000007238 description:"maker-LSalAtl2s406-augustus-gene-2.34") HSP 1 Score: 311.227 bits (796), Expect = 9.432e-94 Identity = 182/484 (37.60%), Postives = 262/484 (54.13%), Query Frame = 0
Query: 109 DPLFKDQWFLNHGAFDGSDMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMPQDNSDNKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDG--LVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSISSASQGGKKPWYLEECSSTLASTYSSGTP-GHDASIATVDQDARLRPDKICTTSHTGTSASAPIAAGVCALALEANPNLTWRDMQHIVVITSNPAPLLRE-SGWRVNAVGRKYSHKFGYGLMDASAMVEVAKVWPGSGRQAICETDTLSLDLPIPVNSGSVARVTLKTDACSGTKKEIRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSLLLPRPRDMTNGGFEDWPFLSVHFWGEPANGTWTLEVNHSPSVKSTSGLAKGIVKKWKMLFYGTRKSP 588
DPL+KD W L + D MN+Q AW++G +GK V V LDDGI HPDL NY P S D ND DP+ N HGT+ +G V +E N CG+GIA++A +G R+ + + RAL+ + IDIY+ + GP++ G T+D P + + GR GKGS+ + A GNGG + C+ SI T+++++ + G P Y E C + + S + S P G TV + C + +GTS+S +A GV AL LEANPNLTWRD+QH+V+ + +L + + W+ NA G +S FG+GLMDA M A W Q +CE + I S V ++L TD+C +I+YLEHVQ + + + RG +++ L SPSGT S++L R D + GF DW LS+ +WGE + G W L V SP + + + K WK++ YGT++ P
Sbjct: 22 DPLWKDSWHLRN---DNISMNIQDAWSRGLSGKGVRVLFLDDGIDRYHPDLYTNYKPELSYDFVDNDNDPIWNRTLKNSHGTKMSGIVGSEGNNSFCGLGIAFHAQLGMARIFNKNVIFEHLNVVRALTYKKDLIDIYTIAVGPQNMGVTLDNV-PEEINEALKETENGRGGKGSLVLLAXGNGGANNEACSFGSNLQSIHTIAVNAVGEEGDIPDYAEPCGAVMTSAFGSSKPRGRGIVTTTVGGN--------CVGNFSGTSSSTAVATGVIALVLEANPNLTWRDVQHLVMSSVVDRDVLDDKANWKRNAAGIYFSEFFGFGLMDAGLMTRRANEWIQVPTQIMCEYKDPQENKII---SEEVVELSLSTDSC-----DIQYLEHVQLQFTAYSLCRGNINLRLESPSGTLSNILRGRETDFSTTGFNDWRLLSLQYWGESSKGKWRLRVFKSPCINRAAKIIA--FKSWKLILYGTKEMP 483
BLAST of endoprotease furin vs. L. salmonis genes
Match: EMLSAG00000009225 (supercontig:LSalAtl2s:LSalAtl2s588:280841:284110:-1 gene:EMLSAG00000009225 transcript:EMLSAT00000009225 description:"maker-LSalAtl2s588-snap-gene-3.14") HSP 1 Score: 307.76 bits (787), Expect = 7.942e-90 Identity = 169/336 (50.30%), Postives = 204/336 (60.71%), Query Frame = 0
Query: 17 GKIYHNHFALHIPEGEAKANRIALNLGFKNRGPIGTLSNHFLFEHEFLRPRCTNHSLEHHEILIKEPGVHWFEQQHERRRFKR-----------------DLSD----------------------SMYISDPLFKDQWFLNHGAFDGSDMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMPQ-DNSD-NKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDGLVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSI 311
G Y N FA+ + G +A+R+A L NRG + + + F H +R R H +L +HW+EQQ R KR DL D S+Y + W+LN G DMNVQ AW G TGK V VTILDDG++ HPDLR+N+DP++S D+N ND+DP P+ D SD NKHGTRCAGEVAA A N ICGVG+AY A IGG+RMLDG V DAVEA +L + HIDIYSASWGP+DDG TVDGPG LA+KAF+ G+ GR GKGSIFVWASGNGGR +NCNCDGYTNSI+TLS+
Sbjct: 18 GISYTNEFAVQVRGGSHEAHRLAQELDCINRGHL--FDDIYRFTHTRIRKRSIQIHSNFHSLLTNHSRIHWWEQQRVLSRKKRQIWAMPAPPQESQYPRGDLIDLARLNDERXVRFFLDVKIGCKSSLYYYLNRWNQMWYLNRGG--KVDMNVQKAWEFGATGKGVHVTILDDGVERSHPDLRQNFDPMSSFDVNDNDDDPTPRYDISDSNKHGTRCAGEVAATANNSICGVGVAYEAGIGGLRMLDGDVTDAVEAHSLLFHNQHIDIYSASWGPDDDGLTVDGPGTLAQKAFMKGIAEGRGGKGSIFVWASGNGGRHXBNCNCDGYTNSIWTLSV 349 HSP 2 Score: 146.362 bits (368), Expect = 6.122e-36 Identity = 105/332 (31.63%), Postives = 148/332 (44.58%), Query Frame = 0
Query: 408 LRESGWRVNAVGRKYSHKFGYGLMDASAMVEVAKVWPGSGRQAICETDTLSLDLPIPVNSGSVARVTLKTDACSGTKKEIRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSLLLPRPRDMTNGGFEDWPFLSVHFWGEPANGTWTLEVNHSPSVKSTSGLAKGIVKKWKMLFYGTRKSPLRQSQLVSEFGPLPSEDFGDGLPGKMMDGSPEDGHNVSPNNNGQHVSWSSGSFSTRAHSGGILEHNKGQSGLLDYESPSSSCHPQCEGNRCSGPKSTECYSCQNFKFGNVCVEHCPLTTYV---SLRGTCQACHSSCQTCSGPNPNQCLTC 736
++ W NAVGR +SH FGYG+MD MV++AK W Q + + + ++ S A T+ G I+YLEHVQ +++ RG + I + SPSGT+S LL RP+D + GF DWPFL+VHFW E GTWTLEV S G + +++W + YGT P Q L + S +P K+ S N S N V Y + PQ CS + E + N + C + CP + Y +++ TC C+ SC+TCSGPN +C +C
Sbjct: 349 VKPRNWDTNAVGRNFSHSFGYGIMDXHCMVKLAKNWVSVPTQLQADI-AGDRRVDVSIHGKSKATSTMNVKDTRG----IKYLEHVQVHVTISAARRGDIIIYIISPSGTRSKLLARRPKDYSQMGFNDWPFLTVHFWEESPFGTWTLEV-------SNDGRSMVQLRRWSLTLYGTSGHP--QQSLTESTIKVSSTVASVDIPEKLKPSS-----NDSSNGKNPQV----------------------------YLNNCVEIDPQVALGWCSSCE--EGFILHNGR----CEKTCPQSYYAGVSNMKPTCVPCYYSCKTCSGPNDYECTSC 627
BLAST of endoprotease furin vs. L. salmonis genes
Match: EMLSAG00000003323 (supercontig:LSalAtl2s:LSalAtl2s182:344829:368713:-1 gene:EMLSAG00000003323 transcript:EMLSAT00000003323 description:"maker-LSalAtl2s182-augustus-gene-4.24") HSP 1 Score: 172.555 bits (436), Expect = 3.101e-46 Identity = 97/213 (45.54%), Postives = 127/213 (59.62%), Query Frame = 0
Query: 313 SASQGGKKPWYLEECSSTLASTYSSGTPGHDASIATVDQDARLRPDKICTTSHTGTSASAPIAAGVCALALEANPNLTWRDMQHIVVITSNPAPLLRESGWRVNAVGRKYSHKFGYGLMDASAMVEVAKVW----PGSGRQAICETDTLSLDLPIPVNSGSVARVTLKTDACSGTKKEIRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSL 521
SASQ G PWY E+CSSTLAST+SSG D IAT D + CT SHTGTSA+AP+AAGV AL LEANPNLTWRD+QH++V +S+ +L+ GW +NA G ++ +FG+G+MDA+ M + A W PG + + + L PV SG +I+YLEH+Q ++ Y RG+L IVL SP G S+L
Sbjct: 245 SASQRGNFPWYGEQCSSTLASTFSSGAYT-DQKIATTDTN------DTCTVSHTGTSAAAPLAAGVIALTLEANPNLTWRDVQHLIVYSSSTNGILKNKGWELNAAGYAFNSRFGFGVMDAATMTKNAMKWKNVSPGLSKTYLGQPGNRDLAPGFPVEILFNIGYERPQRVRSG-DDQIKYLEHIQVVTTIKYAVRGSLEIVLRSPQGKDSTL 449 HSP 2 Score: 105.531 bits (262), Expect = 6.895e-24 Identity = 73/219 (33.33%), Postives = 109/219 (49.77%), Query Frame = 0
Query: 13 ESGHGKIYHNHFALHIPEGEAKANRIALNLGFKNRGPIGTLSNHFLFEHEFLRPRCTNHSLEHHEILIKEPGVHWFEQQHERRRFKRDL--SDSMYISDPLFKDQWFL----NHGAFDGSDMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGN---DEDPMPQDNSD-----NKHGTRCAGEVAAEAFNGICGVGIAYNASIGG 217
+ HG + N + + I + A+ +A N G++N GP+ + LF + ++ S++ I + + W E ERR DL + +D L+ QW++ + + +NV P + G TG V V +LDDG++ H DL NYDP S D N D DP P S+ N HGTRC+GE++ A N CGVG+AYN+ IGG
Sbjct: 34 DDNHG--FSNEWIVQINGYPSDADTLAFNQGYENIGPVTYAAQ--LFHKKRVKRGFMQSSVKKRGINMDILRI-WDE---ERRSKLEDLPLQATFIFNDELWDHQWYMQDTRSRSSLPAIHLNVLPVYEMGITGNEVRVVVLDDGLEWRHSDLIDNYDPSISYDFNNGTLGDNDPTPHYPSNSYASPNSHGTRCSGEISMVANNDKCGVGVAYNSKIGG 244
BLAST of endoprotease furin vs. L. salmonis genes
Match: EMLSAG00000009763 (supercontig:LSalAtl2s:LSalAtl2s631:444502:450665:-1 gene:EMLSAG00000009763 transcript:EMLSAT00000009763 description:"maker-LSalAtl2s631-snap-gene-3.5") HSP 1 Score: 115.546 bits (288), Expect = 4.604e-29 Identity = 69/196 (35.20%), Postives = 102/196 (52.04%), Query Frame = 0
Query: 415 VNAVGRKYSHKFGYGLMDASAMVEVAKVWPGSGRQAICETDTLSLDLPIPVNSGSVARVTLKTDACSGTKKEIRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSLLLPRPRDMTNGGFEDWPFLSVHFWGEPANGTWTLEVNHSPSVKSTSGLAKGIVKKWKMLFYGTRKSPLR--QSQLVSEFGPLPSEDFGD 608
+NA+GR SH +GYGLMD SA+V+VAK W Q C+ ++ IP + +K+ AC +I++LEH SP GT+S+LL RP+D ++ GF +WPF++VH WGE +GTW LE+ H+ + + AK KW + YGT P + + + V+ +P DF D
Sbjct: 1 MNAMGRLVSHSYGYGLMDTSALVKVAKKWNSVPEQMKCKVESPYYYKVIPAMGYITIHLEVKSSAC-----QIKHLEH--------------------SPMGTRSTLLDARPQDYSSNGFTNWPFMTVHSWGEDPSGTWILEI-HNDAYSKLTMHAKFF--KWSLELYGTANDPNQSDEDKDVNVIREVPDTDFLD 168
BLAST of endoprotease furin vs. SwissProt
Match: gi|120611|sp|P09958.2|FURIN_HUMAN (RecName: Full=Furin; AltName: Full=Dibasic-processing enzyme; AltName: Full=Paired basic amino acid residue-cleaving enzyme; Short=PACE; Flags: Precursor) HSP 1 Score: 570.852 bits (1470), Expect = 0.000e+0 Identity = 304/569 (53.43%), Postives = 372/569 (65.38%), Query Frame = 0
Query: 18 KIYHNHFALHIPEGEAKANRIALNLGFKNRGPIGTLSNHFLFEHEFLRPRCTNHSLEHHEILIKEPGVHWFEQQHERRRFKRDLSDSMYISDPLFKDQWFLNHGAFDGSDMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMPQ--DNSDNKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDGLVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSISSASQGGKKPWYLEECSSTLASTYSSGTPGHDASIATVDQDARLRPDKICTTSHTGTSASAPIAAGVCALALEANPNLTWRDMQHIVVITSNPAPLLRESGWRVNAVGRKYSHKFGYGLMDASAMVEVAKVWPGSGRQAICETDTLSLDLPIPVNSGSVARVTLKTDACSGTKKEIRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSLLLPRPRDMTNGGFEDWPFLSVHFWGEPANGTWTLEVNHSPSVKSTSGLAKGIVKKWKMLFYGT 584
K++ N +A+ IP G A AN +A GF N G I +++ F H + R + H L +EP V W EQQ +RR KRD+ +DP F QW+L+ D+NV+ AWA+GYTG +VV+ILDDGI+ +HPDL NYDP AS D+N D DP P+ +DN+HGTRCAGEVAA A NG+CGVG+AYNA IGGVRMLDG V DAVEAR+L LNPNHI IYSASWGPEDDGKTVDGP LA++AF GV GR G GSIFVWASGNGGR+ D+CNCDGYTNSI+TLSISSA+Q G PWY E CSSTLA+TYSSG ++ I T D LR + CT SHTGTSASAP+AAG+ AL LEAN NLTWRDMQH+VV TS PA L + W N VGRK SH +GYGL+DA AMV +A+ W Q C D L+ P + G V AC G I LEH Q +++L Y+ RG L I L SP GT+S+LL RP D + GF DW F++ H W E +G W LE+ ++ + G + K+ ++ YGT
Sbjct: 28 KVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI--FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEP--TDPKFPQQWYLS--GVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQ-NEKQIVTTD----LR--QKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAH-LNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTE----PKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANN-----YGTLTKFTLVLYGT 573
BLAST of endoprotease furin vs. SwissProt
Match: gi|1179699151|sp|P51559.3|BLI4_CAEEL (RecName: Full=Endoprotease bli-4; AltName: Full=Blisterase; AltName: Full=Blistered cuticle protein 4; Flags: Precursor) HSP 1 Score: 569.311 bits (1466), Expect = 0.000e+0 Identity = 351/822 (42.70%), Postives = 438/822 (53.28%), Query Frame = 0
Query: 35 ANRIALNLGFKNRGPIGTLSNHFLFEHEFLRPRCTNHSLEHHEILIKEPGVHWFEQQHERRRFKRD--LSD----------------------------------SMYISDPLFKDQWFLNHGAFDGSDMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMPQDNSDNKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDGLVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSISSASQGGKKPWYLEECSSTLASTYSSGTPGHDASIATVDQDARLRPDKICTTSHTGTSASAPIAAGVCALALEANPNLTWRDMQHIVVITSNPAPLLRESGWRVNAVGRKYSHKFGYGLMDASAMVEVAKVWPGSGRQAICETD-TLSLDLPIPVNSGSVARVTLKTDAC-SGTKKEIRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSLLLPRPRDMTNGGFEDWPFLSVHFWGEPANGTWTLEVNHSPSVKSTSGLAKGIVKKWKMLFYGTRKSPLRQSQLVSEFGPLPSEDFGDGLPGKMMDGSPEDGHNVSPNNNGQHVSWSSGSFSTRAHSGGILEHNKGQSGLLDYESPSSS--CHPQCEGNRCSGPKSTECYSCQNFK--------FGNVCVEHCPLTTYVSLRGTCQACHSSCQTCSGPNPNQCLTCSKSLFLLS-------DQSRCI-----------------------KDQCPSGYRQRPSLNECVPCPYHCESCT 778
A RIA + +G +++FL+ E R R H E L P V W E+Q ++R KRD L D S+ DPL+KDQW+L+ GA G DMNV+ AW +GY G+ V V+ILDDGIQ DHPDL NYDPLASTDIN +D+DP PQ+N DNKHGTRCAGEVAA A N CGVG+A+ A IGGVRMLDG V+D+VEA +LSLN +HIDIYSASWGPEDDGKT DGPGPLA++AF G+K GR GKG+IFVWASGNGG + D+C+ DGYT S++TLSISSA+ +PWYLEEC S++A+TYSS A I TVD CT HTGTSASAP+AAG+ ALALEANP LTWRDMQH+V+ T+N PL GW N VGR S+KFGYGL+D A+V +AK W Q IC + L+ P P+ TL + C SGT + YLEHVQ ++ Y RG L + L SPSGT+S LL PRP+D GF WPFLSV WGE GTW L V +T+ A G W +L YGT P + V P S+ +R H L +S + + +S+ CH +C G +T C++C++ G CV+ C T Y+ C+ C S C TC+ C TC SL L+ D +C+ KD C GY ++ +C C CE+CT
Sbjct: 54 ARRIAADHDMHVKGDPFLDTHYFLYHSETTRTR--RHKRAIVERLDSHPAVEWVEEQRPKKRVKRDYILLDNDVHHSNPFRRSVLNRDGTRRAQRQQPQSPREIPSLPFPDPLYKDQWYLHGGAVGGYDMNVRQAWLQGYAGRNVSVSILDDGIQRDHPDLAANYDPLASTDINDHDDDPTPQNNGDNKHGTRCAGEVAALAGNNQCGVGVAFKAKIGGVRMLDGAVSDSVEAASLSLNQDHIDIYSASWGPEDDGKTFDGPGPLAREAFYRGIKNGRGGKGNIFVWASGNGGSRQDSCSADGYTTSVYTLSISSATYDNHRPWYLEECPSSIATTYSSADFRQPA-IVTVDVPGG------CTDKHTGTSASAPLAAGIIALALEANPELTWRDMQHLVLRTANWKPLENNPGWSRNGVGRMVSNKFGYGLIDGGALVNMAKTWKTVPEQHICTYEYRLANPNPRPIVGRFQLNFTLDVNGCESGTP--VLYLEHVQVHATVRYLKRGDLKLTLFSPSGTRSVLLPPRPQDFNANGFHKWPFLSVQQWGEDPRGTWLLMVESV----TTNPAATGTFHDWTLLLYGT-ADPAQSGDPVYSATPATSQ-----------------------------------GVLSRVHQ---LTSQVEESAPISFPDLTSAGNCHDECNGGCTESSSATSCFACKHLTQTLRNKGGSGFKCVQKCDDTYYLD-GDKCKMCSSHCHTCT--KAEVCETCPGSLLLIDVDNMPHYDHGKCVESCPPGLVADYESNLVQAKCIWRKDLCGDGYYIN-AVGKCDLCDSSCETCT 817
BLAST of endoprotease furin vs. SwissProt
Match: gi|120613|sp|P23377.1|FURIN_RAT (RecName: Full=Furin; AltName: Full=Dibasic-processing enzyme; AltName: Full=Paired basic amino acid residue-cleaving enzyme; Short=PACE; AltName: Full=Prohormone convertase 3; Flags: Precursor) HSP 1 Score: 563.533 bits (1451), Expect = 0.000e+0 Identity = 301/569 (52.90%), Postives = 373/569 (65.55%), Query Frame = 0
Query: 18 KIYHNHFALHIPEGEAKANRIALNLGFKNRGPIGTLSNHFLFEHEFLRPRCTNHSLEHHEILIKEPGVHWFEQQHERRRFKRDLSDSMYISDPLFKDQWFLNHGAFDGSDMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMPQ--DNSDNKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDGLVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSISSASQGGKKPWYLEECSSTLASTYSSGTPGHDASIATVDQDARLRPDKICTTSHTGTSASAPIAAGVCALALEANPNLTWRDMQHIVVITSNPAPLLRESGWRVNAVGRKYSHKFGYGLMDASAMVEVAKVWPGSGRQAICETDTLSLDLPIPVNSGSVARVTLKTDACSGTKKEIRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSLLLPRPRDMTNGGFEDWPFLSVHFWGEPANGTWTLEVNHSPSVKSTSGLAKGIVKKWKMLFYGT 584
KI+ N +A+HI G A A+ +A GF N G I +++ F H + R + H L + P V W EQQ ++R KRD+ +DP F QW+L+ D+NV+ AWA+G+TG+ +VV+ILDDGI+ +HPDL NYDP AS D+N D DP P+ +DN+HGTRCAGEVAA A NG+CGVG+AYNA IGGVRMLDG V DAVEAR+L LNPNHI IYSASWGPEDDGKTVDGP LA++AF GV GR G GSIFVWASGNGGR+ D+CNCDGYTNSI+TLSISSA+Q G PWY E CSSTLA+TYSSG ++ I T D LR + CT SHTGTSASAP+AAG+ AL LEAN NLTWRDMQH+VV TS PA L + W N VGRK SH +GYGL+DA AMV +A+ W Q C + L+ P + G V AC G I LEHVQ +++L Y+ RG L I L SP GT+S+LL RP D + GF DW F++ H W E +G W LE+ ++ + G + K+ ++ YGT
Sbjct: 28 KIFTNTWAVHISGGPAVADSVARKHGFHNLGQI--FGDYYHFWHRAVTKRSLSPHRPRHSRLQRVPQVKWLEQQVAKQRAKRDVYQEP--TDPKFPQQWYLS--GVTQRDLNVKEAWAQGFTGRGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQ-NEKQIVTTD----LR--QKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAH-LNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIEILAE----PKDIGKRLEVRKTVTACLGEPNHISRLEHVQARLTLSYNRRGDLAIHLISPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANN-----YGTLTKFTLVLYGT 573
BLAST of endoprotease furin vs. SwissProt
Match: gi|1191692466|sp|A0A044RE18.1|BLI_ONCVO (RecName: Full=Endoprotease bli; AltName: Full=Blisterase; Flags: Precursor) HSP 1 Score: 557.37 bits (1435), Expect = 0.000e+0 Identity = 292/527 (55.41%), Postives = 353/527 (66.98%), Query Frame = 0
Query: 60 EHEFLRPRCTNHSLEHHEILIKEPGVHWFEQQHERRRFKRDLSDSMYISDPLFKDQWFLNHGAFDGSDMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMPQDNSDNKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDGLVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSISSASQGGKKPWYLEECSSTLASTYSSGTPGHDASIATVDQDARLRPDKICTTSHTGTSASAPIAAGVCALALEANPNLTWRDMQHIVVITSNPAPLLRESGWRVNAVGRKYSHKFGYGLMDASAMVEVAKVWPGSGRQAICETD-TLSLDLPIPVNSGSVARVTLKTDAC-SGTKKEIRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSLLLPRPRDMTNGGFEDWPFLSVHFWGEPANGTWTLEVNHSPSVKSTSGLAKGIVKKWKMLFYGT 584
+ +FL P H L I+ G+ R F + + + DPL+K+QW+LN+GA G DMNVQ AW GY G+ + V+ILDDGIQ DHPDL NYDPLASTDING+D+DP PQD+ DNKHGTRCAGEVA+ A N CGVG+A++A IGGVRMLDG V+D+VEA +LSLN +HIDIYSASWGPEDDG+T DGPGPLA++AF GVK GR GKGSIFVWASGNGG + D+C+ DGYT S++TLS+SSA+ + PWYLEEC ST+A+TYSS A I TVD CT SHTGTSASAP+AAG+ ALALEANPNLTWRDMQHIV+ T+NP PLL GW VN VGR+ ++KFGYGLMDA A+V++A +W Q IC D L P P+ +L+ + C SGT + YLEHVQ + + RG L + L SP GT S LL PRP+D + G WPFLSV WGE G WTL V ST+ G W +L YGT
Sbjct: 115 KRDFLYPDIA-HELAGSSTNIRHTGL--ISNTEPRIDFIQHDAPVLPFPDPLYKEQWYLNNGAQGGFDMNVQAAWLLGYAGRNISVSILDDGIQRDHPDLAANYDPLASTDINGHDDDPTPQDDGDNKHGTRCAGEVASIAGNVYCGVGVAFHAKIGGVRMLDGPVSDSVEAASLSLNRHHIDIYSASWGPEDDGRTFDGPGPLAREAFYRGVKAGRGGKGSIFVWASGNGGSRQDSCSADGYTTSVYTLSVSSATIDNRSPWYLEECPSTIATTYSSANMNQPA-IITVDVPHG------CTRSHTGTSASAPLAAGIIALALEANPNLTWRDMQHIVLRTANPVPLLNNPGWSVNGVGRRINNKFGYGLMDAGALVKLALIWKTVPEQHICTYDYKLEKPNPRPITGNFQMNFSLEVNGCESGTP--VLYLEHVQVLATFRFGKRGDLKLTLFSPRGTSSVLLPPRPQDFNSNGIHKWPFLSVQTWGEDPRGKWTLMVESV----STNRNVGGTFHDWSLLLYGT 625
BLAST of endoprotease furin vs. SwissProt
Match: gi|20141079|sp|P30430.2|FUR1C_DROME (RecName: Full=Furin-like protease 1, isoform 1-CRR; Short=Furin-1; AltName: Full=Kex2-like endoprotease 1; AltName: Full=dKLIP-1; Flags: Precursor) HSP 1 Score: 565.074 bits (1455), Expect = 8.116e-179 Identity = 343/782 (43.86%), Postives = 449/782 (57.42%), Query Frame = 0
Query: 20 YHNHFALHIPEGE-AKANRIALNLGFKNRGPIGTLSNHFLFEHEFLRPRCTNHSLEHHEILIKEPGVHWFEQQHERRRFKRD---------------LSDSMYISDPLFKDQWFLNHGAFDGSDMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMPQ-DNSD-NKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDGLVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSISSASQGGKKPWYLEECSSTLASTYSSGTPGHDASIATVDQDARLRPDKICTTSHTGTSASAPIAAGVCALALEANPNLTWRDMQHIVVITSNPAPLLRESGWRVNAVGRKYSHKFGYGLMDASAMVEVAKVWPGSGRQAICETDTLSLDLPIPVNSGSVARVTLKTDACSGTKKEIRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSLLLPRPRDMTNGGFEDWPFLSVHFWGEPANGTWTLEVNHSPSVKSTSGLAKGIVKKWKMLFYGTRKSPLRQSQLVSEFGPLPSEDFGDGLPGKMMDGSPEDGHN-VSPNNNGQHVSWSSGSFSTRAHSGGILEHNKGQSGLLDYESPSSSCHPQCEGNRCSGPKSTECYSCQNFKFGNVCVEHCPLTTYVSLRGTCQACHSSCQTCSGP-NPNQCLTCSKSLFL---LSDQSRCIKDQCPSGYRQRPSLNECVPCPYH-CESC 777
Y + +A+HIP G+ A+ +A + GF N G I +H+ F H + R + + H L + VHW +QQ + R KRD + D+M +D + W+LN G G DMNV PAW G TGK VVVTILDDG+++DHPD++ NYDP AS D+N +D+DPMP D +D N+HGTRCAGEVAA A N C VGIAY AS+GGVRMLDG V DAVEAR+LSLNP HIDIYSASWGP+DDGKTVDGPG LA +AFI G GR GKGSIF+WASGNGGR+ DNCNCDGYTNSI+TLSISSA++ G PWY E+CSSTLA+TYSSG G + T + CT SHTGTSASAP+AAG+ AL L++N NLTWRD+QHIVV T+ PA L++ W N VGR+ SH FGYGLMDA+ MV VA+ W Q CE + +D IP + ++T+ + C + + YLEHVQ KI+L RG + + L SP+ T +LL PR D + GF WPF+SVH WGE G W LE+++ G + +W M+FYGT ++P + + + PS+ L G M HN V ++ GQ W + G+ G+ S +++C + S K EC + F + C + CP+ TY + + + GP NP SL + L D+ ++ + R+R SL + V P C +C
Sbjct: 231 YTHTWAVHIPNGDNGMADAVAKDHGFVNLGKI--FDDHYHFAHHKVSKRSLSPATHHQTRLDDDDRVHWAKQQRAKSRSKRDFIRMRPSRTSSRAMSMVDAMSFNDSKWPQMWYLNRGG--GLDMNVIPAWKMGITGKGVVVTILDDGLESDHPDIQDNYDPKASYDVNSHDDDPMPHYDMTDSNRHGTRCAGEVAATANNSFCAVGIAYGASVGGVRMLDGDVTDAVEARSLSLNPQHIDIYSASWGPDDDGKTVDGPGELASRAFIEGTTKGRGGKGSIFIWASGNGGREQDNCNCDGYTNSIWTLSISSATEEGHVPWYSEKCSSTLATTYSSGGQGEKQVVTTDLHHS-------CTVSHTGTSASAPLAAGIAALVLQSNQNLTWRDLQHIVVRTAKPAN-LKDPSWSRNGVGRRVSHSFGYGLMDAAEMVRVARNWKAVPEQQRCEINAPHVDKVIPPRTHITLQLTV--NHC----RSVNYLEHVQAKITLTSQRRGDIQLFLRSPANTSVTLLTPRIHDNSRSGFNQWPFMSVHTWGESPQGNWQLEIHN-------EGRYMAQITQWDMIFYGT-ETPAQPDDVAN-----PSQSNQFNLYGNDM------AHNDVEYDSTGQ---WRN-------------MQQVGEVGMTRDHSNTAACL------KWSDRKCLECNDSA-YMFEDQCYDVCPVHTYPLDKFQAEEDEQDDEVTRGPVNPYSSSPMDHSLLMSNSLDDKQDPLQAE---DRRRRSSLTQLVEVPSRVCAAC 949
BLAST of endoprotease furin vs. SwissProt
Match: gi|54037890|sp|P63240.1|NEC1_MUSCO (RecName: Full=Neuroendocrine convertase 1; Short=NEC 1; AltName: Full=Furin homolog; AltName: Full=PC3; AltName: Full=Prohormone convertase 1; AltName: Full=Propeptide-processing protease; AltName: Full=Proprotein convertase 1; Short=PC1; Flags: Precursor) HSP 1 Score: 550.821 bits (1418), Expect = 8.406e-178 Identity = 288/601 (47.92%), Postives = 388/601 (64.56%), Query Frame = 0
Query: 20 YHNHFALHIPEGEAKANRIALNLGFKNRGPIGTLSNHFLFEHEFLRPRCTNHSLEHHEILIKEPGVHWFEQQHERRRFKRDL-SDSMY--ISDPLFKDQWFLNH----GAFDGSDMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMPQDN--SDNKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDGLVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSISSASQGGKKPWYLEECSSTLASTYSSGTPGHDASIATVDQDARLRPDKICTTSHTGTSASAPIAAGVCALALEANPNLTWRDMQHIVVITSNPAPLLRESGWRVNAVGRKYSHKFGYGLMDASAMVEVA--KVWPGSGRQAICETDTLSLDLPIPVNSGSVARVTLKTDACSGTKKEIRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSLLLPRPRDMTNGGFEDWPFLSVHFWGEPANGTWTLEVNHSPSVKSTSGLAKGIVKKWKMLFYGTRKSP--LRQSQLVSEFGPLPSEDFG 607
+ N +A IP G+ A+ IA LG+ G IG+L NH+LF+H+ R +L + L + V W EQQ+E+ R KR + DS +DP++ QW+L A D++V P W KG TGK VV+T+LDDG++ +H D+ NYDP AS D N ND DP P+ + ++NKHGTRCAGE+A +A N CGVG+AYN+ +GG+RMLDG+V DA+EA ++ NP H+DIYSASWGP DDGKTV+GPG LA+KAF GVK GR GKGSIFVWASGNGGR+ DNC+CDGYT+SI+T+SISSASQ G PWY E+CSSTLA++YSSG D I + D L D CT +HTGTSASAP+AAG+ ALALEANPNLTWRDMQH+VV TS PL GW+ N G + +FG+GL++A A+V++A + W + C + + P + + V + T AC G + I+ LEHVQ + ++ Y RG LH+ LTS GT + LL R RD + GF++W F+SVH WGE GTWTL++ S +G + WK++ +GT P ++Q ++ + + + ++ G
Sbjct: 31 FVNEWAAEIPGGQEAASAIAEELGYDLLGQIGSLENHYLFKHKSHPRRSRRSALHITKRLSDDDRVTWAEQQYEKERSKRSVQKDSALDLFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWEKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDHDPFPRYDLTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYT-DQRITSAD----LHND--CTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLASNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRNVPEKKECVVKDNNFE-PRALKANGEVIVEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAVGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPVGTWTLKITD----MSGRMQNEGRIVNWKLILHGTSSQPEHMKQPRVYTSYNTVQNDRRG 619
BLAST of endoprotease furin vs. SwissProt
Match: gi|54041631|sp|P63239.1|NEC1_MOUSE (RecName: Full=Neuroendocrine convertase 1; Short=NEC 1; AltName: Full=Furin homolog; AltName: Full=PC3; AltName: Full=Prohormone convertase 1; AltName: Full=Propeptide-processing protease; AltName: Full=Proprotein convertase 1; Short=PC1; Flags: Precursor) HSP 1 Score: 550.821 bits (1418), Expect = 8.768e-178 Identity = 288/601 (47.92%), Postives = 388/601 (64.56%), Query Frame = 0
Query: 20 YHNHFALHIPEGEAKANRIALNLGFKNRGPIGTLSNHFLFEHEFLRPRCTNHSLEHHEILIKEPGVHWFEQQHERRRFKRDL-SDSMY--ISDPLFKDQWFLNH----GAFDGSDMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMPQDN--SDNKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDGLVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSISSASQGGKKPWYLEECSSTLASTYSSGTPGHDASIATVDQDARLRPDKICTTSHTGTSASAPIAAGVCALALEANPNLTWRDMQHIVVITSNPAPLLRESGWRVNAVGRKYSHKFGYGLMDASAMVEVA--KVWPGSGRQAICETDTLSLDLPIPVNSGSVARVTLKTDACSGTKKEIRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSLLLPRPRDMTNGGFEDWPFLSVHFWGEPANGTWTLEVNHSPSVKSTSGLAKGIVKKWKMLFYGTRKSP--LRQSQLVSEFGPLPSEDFG 607
+ N +A IP G+ A+ IA LG+ G IG+L NH+LF+H+ R +L + L + V W EQQ+E+ R KR + DS +DP++ QW+L A D++V P W KG TGK VV+T+LDDG++ +H D+ NYDP AS D N ND DP P+ + ++NKHGTRCAGE+A +A N CGVG+AYN+ +GG+RMLDG+V DA+EA ++ NP H+DIYSASWGP DDGKTV+GPG LA+KAF GVK GR GKGSIFVWASGNGGR+ DNC+CDGYT+SI+T+SISSASQ G PWY E+CSSTLA++YSSG D I + D L D CT +HTGTSASAP+AAG+ ALALEANPNLTWRDMQH+VV TS PL GW+ N G + +FG+GL++A A+V++A + W + C + + P + + V + T AC G + I+ LEHVQ + ++ Y RG LH+ LTS GT + LL R RD + GF++W F+SVH WGE GTWTL++ S +G + WK++ +GT P ++Q ++ + + + ++ G
Sbjct: 31 FVNEWAAEIPGGQEAASAIAEELGYDLLGQIGSLENHYLFKHKSHPRRSRRSALHITKRLSDDDRVTWAEQQYEKERSKRSVQKDSALDLFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWEKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDHDPFPRYDLTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYT-DQRITSAD----LHND--CTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLASNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRNVPEKKECVVKDNNFE-PRALKANGEVIVEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAVGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPVGTWTLKITD----MSGRMQNEGRIVNWKLILHGTSSQPEHMKQPRVYTSYNTVQNDRRG 619
BLAST of endoprotease furin vs. SwissProt
Match: gi|116242674|sp|P29120.2|NEC1_HUMAN (RecName: Full=Neuroendocrine convertase 1; Short=NEC 1; AltName: Full=Prohormone convertase 1; AltName: Full=Proprotein convertase 1; Short=PC1; Flags: Precursor) HSP 1 Score: 548.125 bits (1411), Expect = 9.906e-177 Identity = 293/625 (46.88%), Postives = 397/625 (63.52%), Query Frame = 0
Query: 20 YHNHFALHIPEGEAKANRIALNLGFKNRGPIGTLSNHFLFEHEFLRPRCTNHSLEHHEILIKEPGVHWFEQQHERRRFKRD-LSDSMY--ISDPLFKDQWFLNH----GAFDGSDMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMPQDN--SDNKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDGLVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSISSASQGGKKPWYLEECSSTLASTYSSGTPGHDASIATVDQDARLRPDKICTTSHTGTSASAPIAAGVCALALEANPNLTWRDMQHIVVITSNPAPLLRESGWRVNAVGRKYSHKFGYGLMDASAMVEVA--KVWPGSGRQAICETDTLSLDLPIPVNSGSVARVTLKTDACSGTKKEIRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSLLLPRPRDMTNGGFEDWPFLSVHFWGEPANGTWTLEV-NHSPSVKSTSGLAKGIVKKWKMLFYGTRKSP--LRQSQLVSEFGPLPSEDFGDGLPGKMMDGSPEDGHNVSPNNN 630
+ N +A IP G A+ IA LG+ G IG+L NH+LF+H+ R + + L + V W EQQ+E+ R KR L DS +DP++ QW+L A D++V P W KG TGK VV+T+LDDG++ +H D+ NYDP AS D N ND DP P+ + ++NKHGTRCAGE+A +A N CGVG+AYN+ +GG+RMLDG+V DA+EA ++ NP H+DIYSASWGP DDGKTV+GPG LA+KAF GVK GR GKGSIFVWASGNGGR+ DNC+CDGYT+SI+T+SISSASQ G PWY E+CSSTLA++YSSG D I + D L D CT +HTGTSASAP+AAG+ ALALEANPNLTWRDMQH+VV TS PL GW+ N G + +FG+GL++A A+V++A + W + C + P + + + + T AC G + I+ LEHVQ + ++ Y RG LH+ LTS +GT + LL R RD + GF++W F+SVH WGE GTWTL + + S +++ +G + WK++ +GT P ++Q ++ + + + ++ G KM+D E +P N
Sbjct: 31 FVNEWAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFKHKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDSALNLFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYT-DQRITSAD----LHND--CTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFE-PRALKANGEVIIEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPIGTWTLRITDMSGRIQN-----EGRIVNWKLILHGTSSQPEHMKQPRVYTSYNTVQNDRRG---VEKMVDPGEEQPTQENPKEN 639
BLAST of endoprotease furin vs. SwissProt
Match: gi|1179699148|sp|O17798.3|FKPC1_CAEEL (RecName: Full=Furin-like protease kpc-1; AltName: Full=CelfurPC protein; Flags: Precursor) HSP 1 Score: 543.502 bits (1399), Expect = 7.082e-176 Identity = 298/608 (49.01%), Postives = 372/608 (61.18%), Query Frame = 0
Query: 18 KIYHNHFALHIPEGEAK-ANRIALNLGFKNRGPIGTLSNHFLFEHEFLRPRCT--NHSLEHHEILIKEPGVHWFEQQHERRRFKR----------------DLSDSMYIS-----------DPLFKDQWFLNHGAFDGS-----DMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMP--QDNSDNKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDGLVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSISSASQGGKKPWYLEECSSTLASTYSSGTPGHDASIATVDQDARLRPDKICTTSHTGTSASAPIAAGVCALALEANPNLTWRDMQHIVVITSNPAPLLRESGWRVNAVGRKYSHKFGYGLMDASAMVEVAKVWPGSGRQAICETDTLSLDLPIPVNSGSVARVTLKTDACSGTKKE--IRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSLLLPRPRDMTNGGFEDWPFLSVHFWGEPANGTWTLEVNHSPSVKSTSGLAKGIVKKWKMLFYGTRK 586
+ Y N +A+ I G+ + ANR+A G+ N GPI ++LF + + R + SL ++ L E V W EQQ +RR KR + D IS DPL+ D W+LN G D NV+ AW GYTGK VVVTILDDG++ HPD+ NYD AS D+N D DPMP + + +N+HGTRCAGEVAA N +C VGIAYNA+IGG+RMLDG V DAVEA ++ N ++IDIYSASWGP+DDG+TVDGP L + AF G+ GR GKGSIFVWASGNGG+ D+CNCDGYTNSI+TLSISSA++ G PWY E CSSTLA+TYSSG G + T A CT HTGTSASAP+AAG+ ALALEANPNLTWRD+QHIV+ T+ P LR W N VGR SH FGYGLMDA AMV++AK+W Q C S IP +G+ ++ L +D C G E + Y+EHVQ ++L RG L I LTSPSGTKS+LL R RD + GF DW F++ H WGE A G W LE+++ G + KW+++ YGT +
Sbjct: 56 RTYTNEWAVRIAGGKVEEANRLANKYGYTNLGPIIPGDEYYLFRDDRKKSRSSRKTRSLSANQ-LQHEEDVMWMEQQVAKRRVKRGYRRIRRHTDDNDIFEEDDDGTQISKSRNRKHPDPNDPLWTDMWYLNRGEHHSDSTTRMDHNVKEAWDLGYTGKGVVVTILDDGLERTHPDISPNYDERASYDVNDRDNDPMPRYEFSDENRHGTRCAGEVAAIFNNSLCIVGIAYNANIGGIRMLDGDVTDAVEAASVGHNADYIDIYSASWGPDDDGRTVDGPAKLTRSAFEKGITMGRKGKGSIFVWASGNGGKDADSCNCDGYTNSIYTLSISSATENGNIPWYSEACSSTLATTYSSGATGEKMILTTDLHHA-------CTNMHTGTSASAPLAAGIVALALEANPNLTWRDLQHIVIRTAKPIN-LRAGDWTTNGVGRNVSHSFGYGLMDAGAMVKLAKIWKKVDEQHRCRQFYPSRYKNIP--NGNRLQLQLYSDGCYGGADENKVSYVEHVQAIVTLKAPKRGDLQIYLTSPSGTKSTLLTKRARDTSRSGFTDWAFMTTHNWGEQAAGLWILEIDN-------DGWDDAELVKWELVLYGTDR 645
BLAST of endoprotease furin vs. SwissProt
Match: gi|14286128|sp|P26016.2|FUR11_DROME (RecName: Full=Furin-like protease 1, isoforms 1/1-X/2; Short=Furin-1; AltName: Full=Kex2-like endoprotease 1; AltName: Full=dKLIP-1; Flags: Precursor) HSP 1 Score: 561.992 bits (1447), Expect = 7.688e-176 Identity = 300/586 (51.19%), Postives = 381/586 (65.02%), Query Frame = 0
Query: 20 YHNHFALHIPEGE-AKANRIALNLGFKNRGPIGTLSNHFLFEHEFLRPRCTNHSLEHHEILIKEPGVHWFEQQHERRRFKRD---------------LSDSMYISDPLFKDQWFLNHGAFDGSDMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMPQ-DNSD-NKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDGLVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSISSASQGGKKPWYLEECSSTLASTYSSGTPGHDASIATVDQDARLRPDKICTTSHTGTSASAPIAAGVCALALEANPNLTWRDMQHIVVITSNPAPLLRESGWRVNAVGRKYSHKFGYGLMDASAMVEVAKVWPGSGRQAICETDTLSLDLPIPVNSGSVARVTLKTDACSGTKKEIRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSLLLPRPRDMTNGGFEDWPFLSVHFWGEPANGTWTLEVNHSPSVKSTSGLAKGIVKKWKMLFYGTRKS 587
Y + +A+HIP G+ A+ +A + GF N G I +H+ F H + R + + H L + VHW +QQ + R KRD + D+M +D + W+LN G G DMNV PAW G TGK VVVTILDDG+++DHPD++ NYDP AS D+N +D+DPMP D +D N+HGTRCAGEVAA A N C VGIAY AS+GGVRMLDG V DAVEAR+LSLNP HIDIYSASWGP+DDGKTVDGPG LA +AFI G GR GKGSIF+WASGNGGR+ DNCNCDGYTNSI+TLSISSA++ G PWY E+CSSTLA+TYSSG G + T + CT SHTGTSASAP+AAG+ AL L++N NLTWRD+QHIVV T+ PA L++ W N VGR+ SH FGYGLMDA+ MV VA+ W Q CE + +D IP + ++T+ + C + + YLEHVQ KI+L RG + + L SP+ T +LL PR D + GF WPF+SVH WGE G W LE+++ + ++++W ++FYGT +S
Sbjct: 231 YTHTWAVHIPNGDNGMADAVAKDHGFVNLGKI--FDDHYHFAHHKVSKRSLSPATHHQTRLDDDDRVHWAKQQRAKSRSKRDFIRMRPSRTSSRAMSMVDAMSFNDSKWPQMWYLNRGG--GLDMNVIPAWKMGITGKGVVVTILDDGLESDHPDIQDNYDPKASYDVNSHDDDPMPHYDMTDSNRHGTRCAGEVAATANNSFCAVGIAYGASVGGVRMLDGDVTDAVEARSLSLNPQHIDIYSASWGPDDDGKTVDGPGELASRAFIEGTTKGRGGKGSIFIWASGNGGREQDNCNCDGYTNSIWTLSISSATEEGHVPWYSEKCSSTLATTYSSGGQGEKQVVTTDLHHS-------CTVSHTGTSASAPLAAGIAALVLQSNQNLTWRDLQHIVVRTAKPAN-LKDPSWSRNGVGRRVSHSFGYGLMDAAEMVRVARNWKAVPEQQRCEINAPHVDKVIPPRTHITLQLTV--NHC----RSVNYLEHVQAKITLTSQRRGDIQLFLRSPANTSVTLLTPRIHDNSRSGFNQWPFMSVHTWGESPQGNWQLEIHNEGRY-----MGHALLREWSLIFYGTTQS 793
BLAST of endoprotease furin vs. nr
Match: gi|1209696022|gb|OWR48567.1| (Endoprotease FURIN [Danaus plexippus plexippus]) HSP 1 Score: 1020.76 bits (2638), Expect = 0.000e+0 Identity = 571/1216 (46.96%), Postives = 709/1216 (58.31%), Query Frame = 0
Query: 19 IYHNHFALHIPEGEAKANRIALNLGFKNRGPIGTLSNHFLFEHEFLRPRCTNHSLEHHEILIKEPGVHWFEQQHERRRFKRD-------------------------LSDSMYISDPLFKDQWFLNHGAFDGSDMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMPQDNSDNKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDGLVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSISSASQGGKKPWYLEECSSTLASTYSSGTPGHDASIATVDQDARLRPDKICTTSHTGTSASAPIAAGVCALALEANPNLTWRDMQHIVVITSNPAPLLRESGWRVNAVGRKYSHKFGYGLMDASAMVEVAKVWPGSGRQAICETDTLSLDLPIPVNSGSVARVTLKTDACSGTKKEIRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSLLLPRPRDMTNGGFEDWPFLSVHFWGEPANGTWTLEVNHSPSVKSTSGLAKGIVKKWKMLFYGTRKSPLRQSQLVSEFGPLPSEDFGDGLPGKMMDGSPEDGHNVSPNNNGQHVS--WSSGSFSTRAHS---GGILEHNKGQSGLLDYESPS--SSCHPQCEGNRCSGPKSTECYSCQNFKFGNVCVEHCPLTTYVSLRGTCQACHSSCQTCSGPNPNQCLTCSKSLFLLSDQSRCIKDQCPSGYRQRPSLNECVPCPYHCESCTETSEGVVNLIEGPRSGSLGIGETTLVCLKCQKGLVRSVLENKCLNGCPFGFSLNPETRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFKTRS-CDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFSKALGGLCAPCGSTCNTCFD-KADNCLSCPKNHVLDLSSCLDHECPNGTFYDTQLNECRHCPHNCMTCESVS--SCSQCGLDHFLTGSGKCSANCQGNEYQTPNGLCLACNRSCEACMGPHSNECLSC-RVGKYLSTTGECLEECLHGFVDKNSQCQACHSSCLACTGPS 1197
+YHNHFA+H+P GE A+ IA GF N G IG L ++L H + R T S EHH L EP V WFEQQ ERRR KRD ++ S + SDPLFK+QW+LN GA DG DMNV PAW +GYTGK VVV+ILDDGIQT+HPDL +NYDPLASTDINGND+DPMPQDN DNKHGTRCAGEVAA A+N CGVGIAYNASIGGVRMLDG+VNDAVEARAL LNP+HIDIYSASWGPEDDGKTVDGPGPLA++AFI GV GR GKGSIFVWASGNGGR D+CNCDGYTNSIFTLSISSA+QGG KPWYLEECSSTLASTYSSGTPGHD S+ATVD D RLR D ICT HTGTSASAP+AAG+CALALEANPNLTWRDMQ++VV+TS P PL +E+GW VN V RK SHKFGYGLMDAS MV +A+ W Q IC++ ++ D I + G +V + + CSGT E+RYLEHVQCKISL + PRG L I+LTSP GT SSLL RPRD+ + F+DWPFLSVHFWGE A G WTL++ ++ + GI+KKW+++FYGT P+R L S+ + F + + + +N N Q+ +++GS +A + G + G++ L D C P+C+ C T+C +C++++ + CV CP ++ + G C CH +C+TC GP + CLTCS + L++D CI+ QCP GY + + C PC HC +C+E ++ C C+ LV + C CP + E SC CHESC TC G C C ++ + +C+ CP+GY D +EC+ CP GC TC C C + W N K C + +C G F S C CH C +C G C C HKCVP+C GY + C C GC C++ C C S C EG ++ G C+ C +C TC + D C SCP+ L C ECP G FY T + CRHC H C C+ C+ C F+ G C Y++ +GLC +C+ SC C GP C +C R + +C++ C + S C C S C S
Sbjct: 24 LYHNHFAIHVPAGEKHADDIATRHGFINHGQIGALKGYYLLSHHGVHKRSTEPSHEHHHKLNNEPEVKWFEQQRERRRMKRDYSPYESTLWSQLSRRLPSHRTRHRAITPSPFFSDPLFKEQWYLNGGAKDGLDMNVMPAWQRGYTGKGVVVSILDDGIQTNHPDLAQNYDPLASTDINGNDDDPMPQDNGDNKHGTRCAGEVAAVAYNQYCGVGIAYNASIGGVRMLDGVVNDAVEARALGLNPDHIDIYSASWGPEDDGKTVDGPGPLARRAFIYGVTSGRRGKGSIFVWASGNGGRHTDSCNCDGYTNSIFTLSISSATQGGFKPWYLEECSSTLASTYSSGTPGHDKSVATVDMDGRLRSDHICTVEHTGTSASAPLAAGICALALEANPNLTWRDMQYLVVLTSRPQPLEKETGWIVNGVKRKVSHKFGYGLMDASEMVNLAEQWVSVPPQHICKSQEINEDKAIESSFGYTLKVHMDVNGCSGTVNEVRYLEHVQCKISLRFFPRGNLRILLTSPMGTTSSLLFERPRDVISSNFDDWPFLSVHFWGERAEGRWTLQIVNAGNRHVNQ---PGILKKWQLIFYGTSTDPIR---LRSKRPAQAAPAFAFPTAADGYEAAGDSFYNTDAFTNYQNFPSLFAAGSNPEKAIARLDGHNVPSPHGENVLADSNDKRVMHDCDPECDSQGCYEKGPTQCIACKHYRLDDACVSRCPPRSFANQGGVCWPCHETCETCVGPGQDSCLTCSPAHLLVADLGLCIQ-QCPDGYWENSEASACRPCAAHCSTCSERAD---------------------ACTSCEHHLV--LYNGTCATSCPPS-TYETEDYSCAKCHESCNTCHGPGEQHCVTCPASSYVLDGRCLSTCPSGYYADKKRKECMKCPIGCATCLA-SLCQSCNSNWEL-NRKGKCVAAGSDRCNAGEFSDGSQCQLCHNDCDSCYGETEGNCLTCPSPNLLQNHKCVPECSRGYYSEA--GRCTRCIHGCSECASRLNCTFCTGSLRLQ------SGTCRTACAEGYYADR--GTCSKCYLSCATCIGPRRDQCASCPRGWRLAAGEC-HPECPQG-FYKTA-DGCRHCHHYCRECDGSGPLHCTSCP-QRFMLDGGLCMECLSSQYYESSSGLCRSCHESCRICSGPGQYSCTACSRPLRLDRLNNQCVQCCSERANNATSDCCHCDSDTGECINSS 1192 HSP 2 Score: 223.016 bits (567), Expect = 3.931e-55 Identity = 162/485 (33.40%), Postives = 218/485 (44.95%), Query Frame = 0
Query: 817 LENKCLNGCPFGFSLNPETRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEHK--CVPDCPAGYRPDVHHQECVPCPQGCHTCSND-QKCIKCQAGWSFANEKEACSPQANAQCPEGSFKTR--SCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFSKALGGLCAPCGSTCNTCFDKAD-NCLSCPKNHVLDLSSCLDHECPNGTFYDTQLNECRHCPHNCMTCESVSSCSQCGLDHFLTGSGKCSANCQGNEYQTPNGLCLACNRSCEACMGPHSNECLSCRVGKYLSTTGECLEECLHGFVDKNSQCQACHSSCLACTGPSLFQCSTCPSGTKLGPQANCLSCEPRKFHDAHSDECLACHESCGTCSGPQDNHCLSCSLPLVLDTWNTTCVPCCE---SSDEKHCCSCTPSRDKCLQPS 1292
L++ C++ CP S + C PCHE+C TC G C C C+ CP GY + C PC C TCS C C+ N A S CP +++T SC CHESC TC G C C ++ + +C+ CP+GY D +EC+ CP GC TC C C + W N K C + +C G FS G C C + C++C+ + + NCL+CP ++L C+ EC G Y ++ C C H C C S +C+ C L SG C C Y G C C SC C+GP ++C SC G L+ GEC EC GF C+ CH C C G C++CP L C+ C +++++ S C +CHESC CSGP C +CS PL LD N CV CC ++ CC C +C+ S
Sbjct: 726 LDDACVSRCP-PRSFANQGGVCWPCHETCETCVGPGQDSCLTCSPAHLLVADLGLCIQQCPDGYWENSEASACRPCAAHCSTCSERADACTSCEHHLVLYNGTCATS------CPPSTYETEDYSCAKCHESCNTCHGPGEQHCVTCPASSYVLDGRCLSTCPSGYYADKKRKECMKCPIGCATCLA-SLCQSCNSNWEL-NRKGKCVAAGSDRCNAGEFSD--GSQCQLCHNDCDSCYGETEGNCLTCPSPNLLQNHKCVP-ECSRG--YYSEAGRCTRCIHGCSECASRLNCTFCTGSLRLQ-SGTCRTAC-AEGYYADRGTCSKCYLSCATCIGPRRDQCASCPRGWRLAA-GECHPECPQGFYKTADGCRHCHHYCRECDGSGPLHCTSCPQRFMLD-GGLCMECLSSQYYESSSGLCRSCHESCRICSGPGQYSCTACSRPLRLDRLNNQCVQCCSERANNATSDCCHCDSDTGECINSS 1192
BLAST of endoprotease furin vs. nr
Match: gi|512908708|ref|XP_004926747.1| (furin-like protease 2 [Bombyx mori] >gi|1200724312|ref|XP_021204031.1| furin-like protease 2 [Bombyx mori]) HSP 1 Score: 1015.37 bits (2624), Expect = 0.000e+0 Identity = 557/1178 (47.28%), Postives = 692/1178 (58.74%), Query Frame = 0
Query: 19 IYHNHFALHIPEGEAKANRIALNLGFKNRGPIGTLSNHFLFEHEFLRPRCTNHSLEHHEILIKEPGVHWFEQQHERRRFKRD-------------------------LSDSMYISDPLFKDQWFLNHGAFDGSDMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMPQDNSDNKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDGLVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSISSASQGGKKPWYLEECSSTLASTYSSGTPGHDASIATVDQDARLRPDKICTTSHTGTSASAPIAAGVCALALEANPNLTWRDMQHIVVITSNPAPLLRESGWRVNAVGRKYSHKFGYGLMDASAMVEVAKVWPGSGRQAICETDTLSLDLPIPVNSGSVARVTLKTDACSGTKKEIRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSLLLPRPRDMTNGGFEDWPFLSVHFWGEPANGTWTLEVNHSPSVKSTSGLAKGIVKKWKMLFYGTRKSPLR-QSQLVSEFGP---LPSEDFG-DGLPGKMMDGSPEDGHNVSPN------NNGQHVSWSSGSFSTRAHSGGILEHNKGQSGLLDYESPSSSCHPQCEGNRCSGPKSTECYSCQNFKFGNVCVEHCPLTTYVSLRGTCQACHSSCQTCSGPNPNQCLTCSKSLFLLSDQSRCIKDQCPSGYRQRPSLNECVPCPYHCESCTETSEGVVNLIEGPRSGSLGIGETTLVCLKCQKGLVRSVLENKCLNGCPFGFSLNPETRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFKTR-SCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFSKALGGLCAPCGSTCNTCFD-KADNCLSCPKNHVLDLSSCLDHECPNGTFYDTQLNECRHCPHNCMTCESVS--SCSQCGLDHFLTGSGKCSANCQGNEYQTPNGLCLACNRSCEACMGPHSNECLSC 1156
+YHNHFA+H+P G + I G+ N G IG+L N++L H + R T S EHH L EP V WFEQQHE+RRFKRD LS Y +DPL+K+QW+LN GA DG DMNV PAW KGYTGK VVV+ILDDGIQT+HPDL +NYDPLASTDINGND+DPMPQDN DNKHGTRCAGEVAA A+N CGVGIAYNASIGGVRMLDG+VNDAVEARAL LNP+HIDIYSASWGPEDDGKTVDGPGPLA++AFI GV GR GKGSIFVWASGNGGR D+CNCDGYTNSIFTLSISSA+QGG KPWYLEECSSTLA+TYSSGTPGHD S+ATVD D RLR D ICT HTGTSASAP+AAG+CALALEANP LTWRDMQ++VV+TS P PL RE GW +N V RK SHKFGYGLMDA+ MV +A+ W Q IC++ L+ D + G+ R + CSGT E+RYLEHVQCKISL + PRG L I+LTSP GT S+LL RPRD+ + F+DWPFLSVHFWGE A G WTLE+ ++ G++KKW+++FYGT P+R +S+ S F P P+ G D + + + PN N + V+ G H +L + + + D C P+C+ C G ++C +C++++ + CV CP +Y + G C CH SC+TC GP + C TC+ + FL++D + C++ QCP GY + C PC HC +C+E + C C+ L+ + E CL CP + +C CH SC TC G QC C + + CV CP GY D +ECV CP GC TC++ C+ C+ W N+K C P + +C G F + C C ++C +C G C C +++CVP+C +GY + C+ C GC C + C C S + AC C +G ++ G C+ C +C TC + D C SCP+ L C ECP G FY + + CRHC H C C C+ C L G G C Y+ NG C C+ SC C G C C
Sbjct: 24 VYHNHFAVHVPSGPEHVDDIVRRHGYVNHGQIGSLKNYYLLSHHEVHKRSTEPSHEHHSKLRDEPQVAWFEQQHEKRRFKRDYNAYDRASFGQLPRRTSPHRAHNRALSSQPYFTDPLYKEQWYLNGGAKDGLDMNVAPAWQKGYTGKGVVVSILDDGIQTNHPDLAQNYDPLASTDINGNDDDPMPQDNGDNKHGTRCAGEVAAVAYNRYCGVGIAYNASIGGVRMLDGIVNDAVEARALGLNPDHIDIYSASWGPEDDGKTVDGPGPLARRAFIYGVTSGRRGKGSIFVWASGNGGRHTDSCNCDGYTNSIFTLSISSATQGGYKPWYLEECSSTLATTYSSGTPGHDKSVATVDMDGRLRADHICTVEHTGTSASAPLAAGICALALEANPELTWRDMQYLVVMTSRPEPLEREKGWIINGVKRKVSHKFGYGLMDATEMVNLAEQWVTVPPQHICKSQELNEDKSMDSTLGNSLRTYMDVTGCSGTVNEVRYLEHVQCKISLRFFPRGNLRILLTSPMGTVSTLLFERPRDVASSTFDDWPFLSVHFWGEQAEGRWTLEIINAGKRHVNQA---GVLKKWQLIFYGTVIDPVRLRSKRPSPFAPSYAFPTAADGYDTISDSFYNTDAFANYQNFPNLFAAGSNPEKAVARLDGHNVPSPHGENVLADSNDKRVMHD-------CDPECDSQGCYGKGPSQCVACKHYRLDDTCVSRCPPRSYANQGGVCWQCHESCETCMGPGQDSCFTCAPAHFLVADLAVCLQ-QCPDGYWEDTDSATCRPCAAHCATCSERAN---------------------ACTSCEHHLL--LHEGSCLVTCPAAH-YETDDYTCAKCHNSCDTCVGPKENQCITCHTTNYVLDGSCVATCPGGYYVDKKRKECVRCPVGCATCTS-AFCLTCETNWEI-NKKGRCLPAGSDRCSTGQFIDKLGCSRCDDACESCYGEGEGHCLTCPSPNLLEDYRCVPECSSGYYAEA--GRCIRCVHGCTECVSRLNCTSCAG--SLRLQSGAC----RTSCADGYYADR--GACSKCYLSCRTCIGPRRDQCASCPQGWRLAAGEC-HPECPQG-FYKSD-DGCRHCHHYCRECSDSGPLHCTSCPPRFVLDG-GLCMECLGSQYYEAGNGTCSTCDPSCRTCYGSGQFSCTGC 1150 HSP 2 Score: 225.713 bits (574), Expect = 5.752e-56 Identity = 171/537 (31.84%), Postives = 238/537 (44.32%), Query Frame = 0
Query: 817 LENKCLNGCPFGFSLNPETRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEH--KCVPDCPAGYRPDVHHQECVPCPQGCHTCSND-QKCIKCQAGWSFANEKEACSPQANAQCPEGSFKT--RSCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFSKALGGLCAPCGSTCNTCFDKAD-NCLSCPKNHVLDLSSCLDHECPNGTFYDTQLNECRHCPHNCMTCESVSSCSQCGLDHFLTGSGKCSANCQGNEYQTPNGLCLACNRSCEACMGPHSNECLSCRVGKYLSTTGECLEECLHGFVDKNSQCQACHSSCLACTGPSLFQCSTCPSGTKLGPQANCLSCEPRKFHDAHSDECLACHESCGTCSGPQDNHCLSCSLPLVLDTWNTTCVPCC-----ESSDEKHCCSCTPSRDKCLQPSKKMLSRKRSSVRFGL-----GDEALTNPSRSLFHYGSLLAILALMTLVIV 1337
L++ C++ CP N + C CHESC TC G C C F C+ CP GY D C PC C TCS C C+ + +C CP ++T +C CH SC TC G QC C + + CV CP GY D +ECV CP GC TC++ C+ C+ W N+K C P + +C G F LG C+ C C +C+ + + +CL+CP ++L+ C+ EC +G Y + C C H C C S +C+ C L SG C +C + Y G C C SC C+GP ++C SC G L+ GEC EC GF + C+ CH C C+ C++CP L C+ C ++++A + C C SC TC G C CS PL LD N CVPCC +S CC C P +C+ S ++ KR +G + + PS + L+ AL +V++
Sbjct: 726 LDDTCVSRCPPRSYAN-QGGVCWQCHESCETCMGPGQDSCFTCAPAHFLVADLAVCLQQCPDGYWEDTDSATCRPCAAHCATCSERANACTSCEH--HLLLHEGSCL----VTCPAAHYETDDYTCAKCHNSCDTCVGPKENQCITCHTTNYVLDGSCVATCPGGYYVDKKRKECVRCPVGCATCTS-AFCLTCETNWEI-NKKGRCLPAGSDRCSTGQFIDKLG--CSRCDDACESCYGEGEGHCLTCPSPNLLEDYRCVP-ECSSG--YYAEAGRCIRCVHGCTECVSRLNCTSCAGSLRLQ-SGACRTSC-ADGYYADRGACSKCYLSCRTCIGPRRDQCASCPQGWRLAA-GECHPECPQGFYKSDDGCRHCHHYCRECSDSGPLHCTSCPPRFVLD-GGLCMECLGSQYYEAGNGTCSTCDPSCRTCYGSGQFSCTGCSRPLRLDRLNNQCVPCCTDRGTTTSPGTECCHCHPETGECINSS---VAGKRRIAEWGALHTVENARSTSAPSAAAITVMVCLSAGALFFVVLM 1241
BLAST of endoprotease furin vs. nr
Match: gi|1344813435|ref|XP_023949719.1| (furin-like protease 2 [Bicyclus anynana]) HSP 1 Score: 1008.82 bits (2607), Expect = 0.000e+0 Identity = 573/1219 (47.01%), Postives = 701/1219 (57.51%), Query Frame = 0
Query: 20 YHNHFALHIPEGEAKANRIALNLGFKNRGPIGTLSNHFLFEHEFLRPRCTNHSLEHHEILIKEPGVHWFEQQHERRRFKRD-----------------------LSDSMYISDPLFKDQWFLNHGAFDGSDMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMPQDNSDNKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDGLVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSISSASQGGKKPWYLEECSSTLASTYSSGTPGHDASIATVDQDARLRPDKICTTSHTGTSASAPIAAGVCALALEANPNLTWRDMQHIVVITSNPAPLLRESGWRVNAVGRKYSHKFGYGLMDASAMVEVAKVWPGSGRQAICETDTLSLDLPIPVNSGSVARVTLKTDACSGTKKEIRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSLLLPRPRDMTNGGFEDWPFLSVHFWGEPANGTWTLEVNHSPSVKSTSGLAKGIVKKWKMLFYGTRKSPLR-QSQLVSEFGPLPSEDFGDGLPGKMMDGSPEDGHNVSPNNNGQHVS--WSSGSFSTRAHS---GGILEHNKGQSGLLDYESPSS--SCHPQCEGNRCSGPKSTECYSCQNFKFGNVCVEHCPLTTYVSLRGTCQACHSSCQTCSGPNPNQCLTCSKSLFLLSDQSRCIKDQCPSGYRQRPSLNECVPCPYHCESCTETSEGVVNLIEGPRSGSLGIGETTLVCLKCQKGLVRSVLENKCLNGCPFGFSLNPETRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFKT-RSCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFSKALGGLCAPCGSTCNTCFD-KADNCLSCPKNHVLDLSSCLDHECPNGTFYDTQLNECRHCPHNCMTCESVSS--CSQCGLDHFLTGSGKCSANCQGNEYQTPNGLCLACNRSCEACMGPHSNECLSC-RVGKYLSTTGECLEECLHGFVDKN----SQCQACHSSCLACTGPSL 1198
YHNHFA+ +P G + + IA GF N G IG L + +L H + R T S +HH LI EP V WFEQQ E+RR KRD ++ S + DPLFK+QW+LN GA DG DMNV PAW KGYTGK VVV+ILDDGIQT+HPDL +NYDP ASTDINGND+DPMPQDN DNKHGTRCAGEVAA A+N CGVGIAYNASIGGVRMLDG+VNDAVEARAL LNP+HIDIYSASWGPEDDGKTVDGPGPLA++AFI GV GR GKGSIFVWASGNGGR D+CNCDGYTNSIFTLSISSA+QGG KPWYLEECSSTLASTYSSGTPGHD S+ATVD D RLR D ICT HTGTSASAP+AAG+CALALEANP+LTWRDMQ++VV+TS P PL +E+GW VN V RK SHKFGYGLMDAS MV +A+ W Q IC++ ++ D PI G V + + CSGT E+RYLEHVQCKISL + PRG L I+LTSP T SSLL RPRD+ + F+DWPFLSVHFWGE A G WTL++ ++ + GI+KKW+++FYGT P+R +S+ S P +G D + +N N Q+ +++GS +A + G + G++ L D +C P+C+ C G T+C SC++++ + CV CP +Y + G C CH C+TC GP + CLTC+ + L++D C + QCP GY + + C PC HC +C+E + +C C+ LV + C CP + + SC CH SC TC+G QC C + + CV CP GY D +EC+ CP GC TC C+ C + W N+K C + QC F +C CH C +C G C C HKCV +C GY P+ C C GC +C++ C C S + AC A C G ++ C C +C TC + D C SCP L C ECP G FY T + CRHC H C C C+ C F+ G C T NG C AC+ SC C GP N C C R K +C+ C V N S C CH C S+
Sbjct: 25 YHNHFAVRVPGGVHRVDDIAKRHGFVNHGQIGALPDFYLLSHHEVHKRSTEPSHDHHHKLINEPHVKWFEQQREKRRIKRDYNQDSLLSQISRRLSPHRTRHRAITSSPFFPDPLFKEQWYLNGGAKDGLDMNVSPAWQKGYTGKGVVVSILDDGIQTNHPDLAQNYDPQASTDINGNDDDPMPQDNGDNKHGTRCAGEVAAVAYNQYCGVGIAYNASIGGVRMLDGVVNDAVEARALGLNPDHIDIYSASWGPEDDGKTVDGPGPLARRAFIYGVTSGRRGKGSIFVWASGNGGRHTDSCNCDGYTNSIFTLSISSATQGGYKPWYLEECSSTLASTYSSGTPGHDKSVATVDMDGRLRADHICTVEHTGTSASAPLAAGICALALEANPDLTWRDMQYLVVLTSRPQPLEKENGWIVNGVKRKVSHKFGYGLMDASEMVNLAEQWITVPPQHICKSQEINEDKPIDPTYGYTLSVHMDVNGCSGTVNEVRYLEHVQCKISLRFFPRGNLRILLTSPMQTTSSLLFERPRDVVSSNFDDWPFLSVHFWGERAEGRWTLQIVNAGNRHVNQ---PGILKKWQLIFYGTASDPVRLRSKRPSALVP----PYGFPTAADGYDSVGDSFYNTDAFTNYQNFPTLFAAGSDPEKAVAQLDGHNIPSPHGENVLADSNDRRVMYNCDPECDSQGCYGSGPTQCISCKHYRLDDACVSRCPPRSYANQGGVCWPCHEYCETCVGPGQDSCLTCAPAYLLVADLGVCTQ-QCPDGYWEDNDSSSCRPCASHCSTCSERAH---------------------LCTSCEHHLV--LYNGTCSASCPPS-TYETDDYSCAKCHTSCDTCSGPGEKQCITCHASNYILDGSCVSTCPGGYYADKKRKECMKCPLGCSTCLA-TFCLSCNSNWEL-NKKGKCVAAGSDQCTSSEFSDGANCKNCHTDCESCYGETEANCLTCPSPYLLQNHKCVMECSRGYYPEA--GRCARCLHGCASCASRLNCTTCSD--SLKLQSGAC----RASCAAGYYADR--STCTKCYISCRTCIGPRRDQCGSCPSGWKLAAGEC-HPECPQG-FYQTD-DGCRHCHHYCRECNGSGPLHCTSCP-PRFMLDGGLCMECLSSQYLDTSNGTCHACDASCRTCSGPGQNSCTGCARPLKLDKLNNQCVRCCSELGVSANSTPPSDCCHCHPDTGECMSSSI 1195 HSP 2 Score: 243.047 bits (619), Expect = 2.033e-61 Identity = 182/545 (33.39%), Postives = 243/545 (44.59%), Query Frame = 0
Query: 817 LENKCLNGCPFGFSLNPETRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEH--KCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQK-CIKCQAGWSFANEKEACSPQANAQCPEGSFKT--RSCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFSKALGGLCAPCGSTCNTCFDKAD-NCLSCPKNHVLDLSSCLDHECPNGTFYDTQLNECRHCPHNCMTCESVSSCSQCGLDHFLTGSGKCSANCQGNEYQTPNGLCLACNRSCEACMGPHSNECLSCRVGKYLSTTGECLEECLHGFVDKNSQCQACHSSCLACTGPSLFQCSTCPSGTKLGPQANCLSCEPRKFHDAHSDECLACHESCGTCSGPQDNHCLSCSLPLVLDTWNTTCVPCC-------ESSDEKHCCSCTPSRDKCLQPSKKMLSRKRSSVRFGLGDEALTNPSRSLFHYGSLLAILALMTL-VIVKYFKRAKIRL 1347
L++ C++ CP N + C PCHE C TC G C C C CP GY D C PC C TCS C C+ N CS A CP +++T SC CH SC TC+G QC C + + CV CP GY D +EC+ CP GC TC C+ C + W N+K C + QC FS G C C + C +C+ + + NCL+CP ++L C+ EC G Y + C C H C +C S +C+ C D SG C A+C Y C C SC C+GP ++C SC G L+ GEC EC GF + C+ CH C C G C++CP L C+ C ++ D + C AC SC TCSGP N C C+ PL LD N CV CC S+ CC C P +C+ S + ++R+S L A P+ SLF ++AL+ L V+V +R++ +L
Sbjct: 724 LDDACVSRCPPRSYAN-QGGVCWPCHEYCETCVGPGQDSCLTCAPAYLLVADLGVCTQQCPDGYWEDNDSSSCRPCASHCSTCSERAHLCTSCEHHLVLYNG--TCS----ASCPPSTYETDDYSCAKCHTSCDTCSGPGEKQCITCHASNYILDGSCVSTCPGGYYADKKRKECMKCPLGCSTCLA-TFCLSCNSNWEL-NKKGKCVAAGSDQCTSSEFSD--GANCKNCHTDCESCYGETEANCLTCPSPYLLQNHKCV-MECSRG--YYPEAGRCARCLHGCASCASRLNCTTCS-DSLKLQSGACRASCAAG-YYADRSTCTKCYISCRTCIGPRRDQCGSCPSGWKLAA-GECHPECPQGFYQTDDGCRHCHHYCRECNGSGPLHCTSCPPRFMLD-GGLCMECLSSQYLDTSNGTCHACDASCRTCSGPGQNSCTGCARPLKLDKLNNQCVRCCSELGVSANSTPPSDCCHCHPDTGECM--SSSIAGKRRNSESAALHTVASERPA-SLFSIVIAGGVVALVVLSVMVVQLRRSRHQL 1247
BLAST of endoprotease furin vs. nr
Match: gi|1229700120|ref|XP_022130459.1| (furin-like protease 2 [Pieris rapae]) HSP 1 Score: 1008.82 bits (2607), Expect = 0.000e+0 Identity = 559/1174 (47.61%), Postives = 702/1174 (59.80%), Query Frame = 0
Query: 20 YHNHFALHIPEGEAKANRIALNLGFKNRGPIGTLSNHFLFEHEFLRPRCTNHSLEHHEILIKEPGVHWFEQQHERRRFKRD-------------------------LSDSMYISDPLFKDQWFLNHGAFDGSDMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMPQDNSDNKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDGLVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSISSASQGGKKPWYLEECSSTLASTYSSGTPGHDASIATVDQDARLRPDKICTTSHTGTSASAPIAAGVCALALEANPNLTWRDMQHIVVITSNPAPLLRESGWRVNAVGRKYSHKFGYGLMDASAMVEVAKVWPGSGRQAICETDTLSLDLPIPVNSGSVARVTLKTDACSGTKKEIRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSLLLPRPRDMTNGGFEDWPFLSVHFWGEPANGTWTLEVNHSPSVKSTSGLAKGIVKKWKMLFYGTRKSPLRQS-QLVSEFGPLPSEDFGDGLPGKMMDGSPEDGHNVSPNNNGQHVS--WSSGSFSTRAHS---GGILEHNKGQSGLLDYESPSS--SCHPQCEGNRCSGPKSTECYSCQNFKFGNVCVEHCPLTTYVSLRGTCQACHSSCQTCSGPNPNQCLTCSKSLFLLSDQSRCIKDQCPSGYRQRPSLNECVPCPYHCESCTETSEGVVNLIEGPRSGSLGIGETTLVCLKCQKGLVRSVLENKCLNGCPFGFSLNPETRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSF-KTRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFSKALGGLCAPCGSTCNTCFD-KADNCLSCPKNHVLDLSSCLDHECPNGTFYDTQLNECRHCPHNCMTCESVSS--CSQCGLDHFLTGSGKCSANCQGNEYQTPNGLCLACNRSCEACMGPHSNECLSC 1156
YHNHFA+ + +G + IAL GF+N G IG+L +L H + R S EHH+ L EP V WFEQQ ERRR KRD ++ S++ DPLFK+QW+LN GA DG DMNV PAW KGYTGK VVV+ILDDGIQT+HPDL++NYD LASTDINGND+DPMPQDN DNKHGTRCAGEVAA A+N CGVGIAYNASIGGVRMLDG+VNDAVEARAL LNP+HIDIYSASWGPEDDGKTVDGPGPLA++AFI GV GR GKGSIFVWASGNGGR D+CNCDGYTNSIFTLSISSA+QGG KPWYLEECSSTLA+TYSSGTPGHD S+ATVD DARLRPD+ICT HTGTSASAP+AAG+CALALEANP+LTWRDMQ++VV+TS P PL +ESGW VN + RK SHKFGYGLMDAS MV +A+ W Q IC++ ++ D I + G + + CSGT E+R+LEHVQCKISL + PRG L I+LTSP GT S+LL RPRD+ + F+DWPFLSVHFWGE A G WTL++ ++ + GI+KKW+++FYGT P+R S + S G P F G+ G D + +N N Q+ +++GS +A + G + G++ L D C P+C+ C G T+C +C++++ + CV CP ++ + G C CH SC+TC GP + CLTC+ + L++D + C++ QCP GY + + C C HC +C++ ++ C C+ LV + C+ CP + E SC CH SC TC G QC C + + +CV CP+ Y D +EC+ CP GC C + C+ C W N+K C P N +C G F + +C C+E+C TC G C C +KCV +C GY P+ C C GC C++ C C+ S + AC C EG ++ G+C+ C +C TC + D C SCP L C ECP G FY T+ + CRHC H C C+ C C L G G C Y +G C +C+ SC C GP C C
Sbjct: 25 YHNHFAIQVLDGPEHVDDIALRHGFENHGQIGSLKGFYLLSHHKVHKRSLEPSHEHHKKLNDEPQVRWFEQQRERRRVKRDYKPYEGALWSQLARRPASHRTRHRAITPSLF-PDPLFKEQWYLNGGAKDGLDMNVAPAWQKGYTGKGVVVSILDDGIQTNHPDLKQNYDALASTDINGNDDDPMPQDNGDNKHGTRCAGEVAAVAYNQYCGVGIAYNASIGGVRMLDGIVNDAVEARALGLNPDHIDIYSASWGPEDDGKTVDGPGPLARRAFIYGVTSGRRGKGSIFVWASGNGGRHTDSCNCDGYTNSIFTLSISSATQGGYKPWYLEECSSTLATTYSSGTPGHDKSVATVDMDARLRPDRICTVEHTGTSASAPLAAGICALALEANPDLTWRDMQYLVVMTSRPQPLEKESGWIVNGIKRKVSHKFGYGLMDASEMVNLAEQWISVPPQHICKSQEINEDKAIDSSYGYTLKAHMDVTGCSGTVNEVRFLEHVQCKISLRFFPRGNLRILLTSPMGTTSTLLFERPRDVVSSNFDDWPFLSVHFWGERAEGRWTLQIVNAGNRHVNQ---PGILKKWQLIFYGTNVDPVRLSTKRPSALG--PPFGFPTGVDG--YDTVGDSFYNTDAFTNYQNFPSLFAAGSDPEKAIARLDGHNIPSTHGENVLADSNDKRVMHDCDPECDAQGCYGKGPTQCIACKHYRLDDACVSRCPPRSFANQGGVCWPCHESCETCIGPGQDSCLTCAPAHLLVADLAVCLQ-QCPDGYYEDSDASVCRACAMHCSTCSDRAD---------------------ACTSCEHHLV--LYNGTCVASCP-PTTYETEDDSCANCHTSCDTCMGPGPVQCITCHPSNYILDGRCVNSCPSAYYADKKRKECLKCPVGCSNCLS-SFCLSCDTNWEL-NKKGKCLPVGNDRCSAGEFSSSNTCQNCNEACDTCYGEDEKNCLTCPAPNLLQNYKCVSECGRGYYPEA--GRCAKCVHGCSQCASRLNCTSCEG--SLRLQSGAC----RTSCAEGYYADR--GVCSKCYLSCRTCSGPRRDQCASCPSGWRLAAGECYP-ECPQG-FYKTE-DGCRHCHHYCRECDGSGPLHCKSCPPGFMLDG-GLCMECLGSQYYDKSSGTCHSCHDSCRTCSGPGQFSCTGC 1149 HSP 2 Score: 244.202 bits (622), Expect = 8.805e-62 Identity = 174/536 (32.46%), Postives = 232/536 (43.28%), Query Frame = 0
Query: 817 LENKCLNGCPFGFSLNPETRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEH--KCVPDCPAGYRPDVHHQECVPCPQGCHTCSND-QKCIKCQAGWSFANEKEACSPQANAQCPEGSFKTR--SCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFSKALGGLCAPCGSTCNTCF-DKADNCLSCPKNHVLDLSSCLDHECPNGTFYDTQLNECRHCPHNCMTCESVSSCSQCGLDHFLTGSGKCSANCQGNEYQTPNGLCLACNRSCEACMGPHSNECLSCRVGKYLSTTGECLEECLHGFVDKNSQCQACHSSCLACTGPSLFQCSTCPSGTKLGPQANCLSCEPRKFHDAHSDECLACHESCGTCSGPQDNHCLSCSLPLVLDTWNTTCVPCCESSDEK---------HCCSCTPSRDKCLQPSKKMLSRKRSSVRFGLGDEALTNPSRSLFHYGSLLAILALMTLVIV 1337
L++ C++ CP S + C PCHESC TC G C C C+ CP GY D C C C TCS+ C C+ N A CP +++T SC CH SC TC G QC C + + +CV CP+ Y D +EC+ CP GC C + C+ C W N+K C P N +C G FS + C C C+TC+ + NCL+CP ++L C+ EC G Y + C C H C C S +C+ C L SG C +C Y G+C C SC C GP ++C SC G L+ GEC EC GF C+ CH C C G C +CP G L C+ C +++D S C +CH+SC TCSGP C CS PL D N CVPCC S + CC C P C+ S ++ KR +G + PS++ + G + + ++V
Sbjct: 725 LDDACVSRCP-PRSFANQGGVCWPCHESCETCIGPGQDSCLTCAPAHLLVADLAVCLQQCPDGYYEDSDASVCRACAMHCSTCSDRADACTSCEHHLVLYNGT------CVASCPPTTYETEDDSCANCHTSCDTCMGPGPVQCITCHPSNYILDGRCVNSCPSAYYADKKRKECLKCPVGCSNCLS-SFCLSCDTNWEL-NKKGKCLPVGNDRCSAGEFSSS--NTCQNCNEACDTCYGEDEKNCLTCPAPNLLQNYKCVS-ECGRG--YYPEAGRCAKCVHGCSQCASRLNCTSCEGSLRLQ-SGACRTSC-AEGYYADRGVCSKCYLSCRTCSGPRRDQCASCPSGWRLAA-GECYPECPQGFYKTEDGCRHCHHYCRECDGSGPLHCKSCPPGFMLD-GGLCMECLGSQYYDKSSGTCHSCHDSCRTCSGPGQFSCTGCSRPLRFDRLNNQCVPCCSESSQAANSTPASTPDCCHCHPDTGDCINSS---VAGKRRIAEWGALQSSNDTPSKTPLNPGMMFLVFIAAGTIVV 1239
BLAST of endoprotease furin vs. nr
Match: gi|1274120639|ref|XP_022824388.1| (furin-like protease 2 [Spodoptera litura] >gi|1274120641|ref|XP_022824389.1| furin-like protease 2 [Spodoptera litura]) HSP 1 Score: 1005.36 bits (2598), Expect = 0.000e+0 Identity = 552/1178 (46.86%), Postives = 699/1178 (59.34%), Query Frame = 0
Query: 19 IYHNHFALHIPEGEAKANRIALNLGFKNRGPIGTLSNHFLFEHEFLRPRCTNHSLEHHEILIKEPGVHWFEQQHERRRFKRD-------------------------LSDSMYISDPLFKDQWFLNHGAFDGSDMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMPQDNSDNKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDGLVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSISSASQGGKKPWYLEECSSTLASTYSSGTPGHDASIATVDQDARLRPDKICTTSHTGTSASAPIAAGVCALALEANPNLTWRDMQHIVVITSNPAPLLRESGWRVNAVGRKYSHKFGYGLMDASAMVEVAKVWPGSGRQAICETDTLSLDLPIPVNSGSVARVTLKTDACSGTKKEIRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSLLLPRPRDMTNGGFEDWPFLSVHFWGEPANGTWTLEVNHSPSVKSTSGLAKGIVKKWKMLFYGTRKSPLR-QSQLVSEFGP---LPS-----EDFGDGLPGKMMDGSPEDGHNV--SPNNNGQHVSWSSGSFSTRAHSGGILEHNKGQSGLLDYESPSSSCHPQCEGNRCSGPKSTECYSCQNFKFGNVCVEHCPLTTYVSLRGTCQACHSSCQTCSGPNPNQCLTCSKSLFLLSDQSRCIKDQCPSGYRQRPSLNECVPCPYHCESCTETSEGVVNLIEGPRSGSLGIGETTLVCLKCQKGLVRSVLENKCLNGCPFGFSLNPETRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFKT-RSCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFSKALGGLCAPCGSTCNTCFD-KADNCLSCPKNHVLDLSSCLDHECPNGTFYDTQLNECRHCPHNCMTCESVSS--CSQCGLDHFLTGSGKCSANCQGNEYQTPNGLCLACNRSCEACMGPHSNECLSC 1156
+YH+ FA+H+P G + IA GF N G IG+L N++L H +R R T S EHH+ L EP V WFEQQ E+RR KRD L+ S + DPLFK+QW+LN GA DG DMNV PAW KGYTGK VVV+ILDDGIQT+HPDL +NYDP ASTDINGND+DPMPQDN DNKHGTRCAGEVAA A+N CGVGIAYNASIGGVRMLDG+VNDAVEARAL LNP+HIDIYSASWGPEDDGKTVDGPGPLA++AFI GV GR GKGSIFVWASGNGGR D+CNCDGYTNSIFTLSISSA+QGG KPWYLEECSSTLA+TYSSGTPGHD S+ATVD D RLR D ICT HTGTSASAP+AAG+CALALEANP LTWRDMQ++VV+TS P PL +E GW +N V RK SHKFGYGLMDAS MV +A+ W Q IC++ ++ D I G + + CS T E+RYLEHVQCKISL + PRG L I+LTSP GT S+LL RPRD+ + F+DWPFLSVHFWGE A G WTL++ ++ + G++KKW+++FYGT P+R +++ S P P+ E GD + ++ N+ + ++ + V+ G H +L + + + D C P+C+ C G T+C +C++++ + CV CP +Y + G C CH SC+TC GP + CLTC+ + L++D + C++ QCP GY + + C PC HC +C+E ++G C C+ LV + + C+ CP E C CHESC TC G TQC C T+ + +CV CP Y D +EC+ CP GC TC++ C+ C++ W N+K C P + +C G F + C C+ +C +C G C C + ++KCVP+C GY + C C GC C + C C + + AC C +G ++ G C+ C +C TC + D C SCP+ L C ECP G FY + L CRHC H C C+ C C F+ G C Y +G C +C+ SC C GP C +C
Sbjct: 24 VYHDQFAVHVPAGSHHVDDIARRHGFVNHGQIGSLKNYYLLSHHEVRKRSTEPSHEHHKKLNDEPQVRWFEQQREKRRIKRDYSPYDRAAFSQLSRRLQPHRPHYRALTSSPFFPDPLFKEQWYLNGGAKDGLDMNVAPAWQKGYTGKGVVVSILDDGIQTNHPDLAQNYDPNASTDINGNDDDPMPQDNGDNKHGTRCAGEVAAVAYNQYCGVGIAYNASIGGVRMLDGVVNDAVEARALGLNPDHIDIYSASWGPEDDGKTVDGPGPLARRAFIYGVTSGRRGKGSIFVWASGNGGRHTDSCNCDGYTNSIFTLSISSATQGGYKPWYLEECSSTLATTYSSGTPGHDKSVATVDMDGRLRSDHICTVEHTGTSASAPLAAGICALALEANPELTWRDMQYLVVMTSRPQPLEKEGGWIINGVKRKVSHKFGYGLMDASEMVSLAEQWVSVPPQHICKSQEINEDKQIESTFGYTLSTHMDVNGCSSTVNEVRYLEHVQCKISLRFFPRGNLRILLTSPMGTVSTLLFERPRDVVSSNFDDWPFLSVHFWGEHAEGRWTLQIVNAGNRHVNQA---GLLKKWQLIFYGTAVDPVRLRTKRPSPVAPPFAFPTAADGYETIGDSFYNTDAFANYQNFPNLFAAGSDPEKAVARLDGHNVPSPHGENVLADSNDKRVMHD-------CDPECDSQGCYGKGPTQCIACKHYRLDDSCVSRCPPRSYANQGGVCWPCHESCETCVGPGQDSCLTCAPAHLLVADLAVCLQ-QCPDGYWEDSEASVCRPCAAHCATCSERADG---------------------CTSCEHHLV--LHDGTCMASCPPSH-YETEDDMCAKCHESCDTCQGPGETQCVTCHPSTYALDGRCVTSCPPAYYADKKRKECMRCPVGCLTCTSG-FCLSCESNWEL-NKKGKCMPVGSDKCSAGEFAVDQKCKRCNPACDSCYGENEGHCLTCPNPNLLQDYKCVPECSKGYYAEA--GRCARCMHGCSDCVSRLNCTSCVSALRL--QSGAC----RTSCADGYYADR--GTCSKCYLSCRTCIGPRRDQCASCPEGWRLAAGEC-HPECPQG-FYQS-LGGCRHCHHYCRECDGSGPLHCKSCP-PRFMLDGGLCMECLGSQYYDATSGTCRSCDASCRTCSGPGQFSCSTC 1150 HSP 2 Score: 240.35 bits (612), Expect = 1.396e-60 Identity = 173/533 (32.46%), Postives = 235/533 (44.09%), Query Frame = 0
Query: 817 LENKCLNGCPFGFSLNPETRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEH--KCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQK-CIKCQAGWSFANEKEACSPQANAQCPEGSFKTRS--CDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFSKALGGLCAPCGSTCNTCFDKAD-NCLSCPKNHVLDLSSCLDHECPNGTFYDTQLNECRHCPHNCMTCESVSSCSQCGLDHFLTGSGKCSANCQGNEYQTPNGLCLACNRSCEACMGPHSNECLSCRVGKYLSTTGECLEECLHGFVDKNSQCQACHSSCLACTGPSLFQCSTCPSGTKLGPQANCLSCEPRKFHDAHSDECLACHESCGTCSGPQDNHCLSCSLPLVLDTWNTTCVPCCE------SSDEKHCCSCTPSRDKCLQPSKKMLSRKRSSVRFGLGDEALTNPSRSLFHYGSLLAILALMTLVIV 1337
L++ C++ CP N + C PCHESC TC G C C C+ CP GY D C PC C TCS C C+ + A CP ++T C CHESC TC G TQC C T+ + +CV CP Y D +EC+ CP GC TC++ C+ C++ W N+K C P + +C G F A+ C C C++C+ + + +CL+CP ++L C+ EC G Y + C C H C C S +C+ C + SG C +C + Y G C C SC C+GP ++C SC G L+ GEC EC GF C+ CH C C G C +CP L C+ C +++DA S C +C SC TCSGP C +CS PL +D N CVPCC S+ CC C P +C+ S R A + PS ++ A + L +V+V
Sbjct: 726 LDDSCVSRCPPRSYAN-QGGVCWPCHESCETCVGPGQDSCLTCAPAHLLVADLAVCLQQCPDGYWEDSEASVCRPCAAHCATCSERADGCTSCEHHLVLHDGT------CMASCPPSHYETEDDMCAKCHESCDTCQGPGETQCVTCHPSTYALDGRCVTSCPPAYYADKKRKECMRCPVGCLTCTSG-FCLSCESNWEL-NKKGKCMPVGSDKCSAGEF--AVDQKCKRCNPACDSCYGENEGHCLTCPNPNLLQDYKCVP-ECSKG--YYAEAGRCARCMHGCSDCVSRLNCTSC-VSALRLQSGACRTSC-ADGYYADRGTCSKCYLSCRTCIGPRRDQCASCPEGWRLAA-GECHPECPQGFYQSLGGCRHCHHYCRECDGSGPLHCKSCPPRFMLD-GGLCMECLGSQYYDATSGTCRSCDASCRTCSGPGQFSCSTCSRPLRIDRLNNQCVPCCSERGVTNSTPSSDCCHCNPDNGECINSSVAGKRRIAEWGALHTAPSAQSAPSAAVVTLAVCAAAVGLFIVVLV 1240
BLAST of endoprotease furin vs. nr
Match: gi|1167860|emb|CAA93116.1| (Endoprotease FURIN [Spodoptera frugiperda]) HSP 1 Score: 1005.36 bits (2598), Expect = 0.000e+0 Identity = 553/1178 (46.94%), Postives = 698/1178 (59.25%), Query Frame = 0
Query: 19 IYHNHFALHIPEGEAKANRIALNLGFKNRGPIGTLSNHFLFEHEFLRPRCTNHSLEHHEILIKEPGVHWFEQQHERRRFKRD-------------------------LSDSMYISDPLFKDQWFLNHGAFDGSDMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMPQDNSDNKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDGLVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSISSASQGGKKPWYLEECSSTLASTYSSGTPGHDASIATVDQDARLRPDKICTTSHTGTSASAPIAAGVCALALEANPNLTWRDMQHIVVITSNPAPLLRESGWRVNAVGRKYSHKFGYGLMDASAMVEVAKVWPGSGRQAICETDTLSLDLPIPVNSGSVARVTLKTDACSGTKKEIRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSLLLPRPRDMTNGGFEDWPFLSVHFWGEPANGTWTLEVNHSPSVKSTSGLAKGIVKKWKMLFYGTRKSPLR-QSQLVSEFGP---LPS-----EDFGDGLPGKMMDGSPEDGHNV--SPNNNGQHVSWSSGSFSTRAHSGGILEHNKGQSGLLDYESPSSSCHPQCEGNRCSGPKSTECYSCQNFKFGNVCVEHCPLTTYVSLRGTCQACHSSCQTCSGPNPNQCLTCSKSLFLLSDQSRCIKDQCPSGYRQRPSLNECVPCPYHCESCTETSEGVVNLIEGPRSGSLGIGETTLVCLKCQKGLVRSVLENKCLNGCPFGFSLNPETRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFKT-RSCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFSKALGGLCAPCGSTCNTCFD-KADNCLSCPKNHVLDLSSCLDHECPNGTFYDTQLNECRHCPHNCMTCESVSS--CSQCGLDHFLTGSGKCSANCQGNEYQTPNGLCLACNRSCEACMGPHSNECLSC 1156
+YH+ FA+H+P G + IA GF N G IG+L N++L H +R R T S EHH+ L EP V WFEQQ E+RR KRD L+ S + DPLFK+QW+LN GA DG DMNV PAW KGYTGK VVV+ILDDGIQT+HPDL +NYDP ASTDINGNDEDPMPQDN DNKHGTRCAGEVAA A+N CGVGIAYNASIGGVRMLDG+VNDAVEARAL LNP+HIDIYSASWGPEDDGKTVDGPGPLA++AFI GV GR GKGSIFVWASGNGGR D+CNCDGYTNSIFTLSISSA+QGG KPWYLEECSSTLA+TYSSGTPGHD S+ATVD D RLR D ICT HTGTSASAP+AAG+CALALEANP LTWRDMQ++VV+TS P PL +E GW +N V RK SHKFGYGLMDAS MV +A+ W Q IC++ ++ D I G + + CS T E+RYLEHVQCKISL + PRG L I+LTSP GT S+LL RPRD+ + F+DWPFLSVHFWGE A G WTL++ ++ + GI+KKW+++FYGT P+R +++ S P P+ E GD + ++ N+ + ++ + V+ G H +L + + + D C P+C+ C G T+C +C++++ + CV CP +Y + G C CH SC+TC GP + CLTC+ + L++D + C++ QCP GY + + C PC HC +C+E ++G C C+ LV + + C+ CP E C CHESC TC G TQC C T+ + +CV CP Y D +EC+ CP GC TC++ C+ C+ W N+K C P + +C G F + C C+ +C +C G C C + ++KCVP+C GY + C C GC C + C C + + + AC C +G ++ G C+ C +C TC + D C SCP+ L C ECP G FY + CRHC H C C+ C C F+ G C Y +G C +C+ SC C GP C +C
Sbjct: 24 VYHDQFAVHVPAGPHHVDDIARRHGFVNHGQIGSLKNYYLLSHHEVRKRSTEPSHEHHKKLNDEPQVRWFEQQREKRRIKRDYSPYDRASFSQLSRRLQPHRTNYRALTSSPFFPDPLFKEQWYLNGGAKDGLDMNVAPAWQKGYTGKGVVVSILDDGIQTNHPDLAQNYDPNASTDINGNDEDPMPQDNGDNKHGTRCAGEVAAVAYNQYCGVGIAYNASIGGVRMLDGVVNDAVEARALGLNPDHIDIYSASWGPEDDGKTVDGPGPLARRAFIYGVTSGRRGKGSIFVWASGNGGRHTDSCNCDGYTNSIFTLSISSATQGGYKPWYLEECSSTLATTYSSGTPGHDKSVATVDMDGRLRSDHICTVEHTGTSASAPLAAGICALALEANPELTWRDMQYLVVMTSRPQPLEKEGGWIINGVKRKVSHKFGYGLMDASEMVSLAEQWVSVPPQHICKSQEINEDKQIESTFGYTLSAHMDVNGCSSTVNEVRYLEHVQCKISLRFFPRGNLRILLTSPMGTVSTLLFERPRDVVSSNFDDWPFLSVHFWGEHAEGRWTLQIVNAGNRHVNQA---GILKKWQLIFYGTSVDPVRLRTKRPSPVAPPFAFPTAADGYETIGDSFYNTDAFANYQNFPNLFAAGSDPEKAVARLDGHNVPSPHGENVLADSNDKRVMHD-------CDPECDSQGCYGKGPTQCIACKHYRLDDSCVSRCPPRSYANQGGVCWPCHESCETCVGPGQDSCLTCAPAHLLVADLAVCLQ-QCPDGYWEDSEASVCRPCAAHCATCSERADG---------------------CTSCEHHLV--LHDGTCMASCPPSH-YETEDDMCAKCHESCDTCQGPGETQCVTCHPSTYALDGRCVTSCPPAYYADKKRKECMRCPVGCSTCTS-AFCLSCEPKWEL-NKKGKCMPVGSDKCSAGEFAVDQKCKRCNPACDSCYGENEGHCLTCPNPNLLQDYKCVPECSKGYYAEA--GRCARCMHGCSDCVSRLNCTSCAS--TLRLQSGAC----RTSCADGYYADR--GTCSKCYLSCRTCIGPRRDQCASCPEGWRLAAGEC-HPECPQG-FYQSP-GGCRHCHHYCRECDGSGPLHCKSCP-PRFMLDGGLCMECLGSQYYDATSGTCRSCDASCRTCSGPGQFSCTTC 1150 HSP 2 Score: 238.81 bits (608), Expect = 4.215e-60 Identity = 176/536 (32.84%), Postives = 237/536 (44.22%), Query Frame = 0
Query: 817 LENKCLNGCPFGFSLNPETRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEH--KCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQK-CIKCQAGWSFANEKEACSPQANAQCPEGSFKTRS--CDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFSKALGGLCAPCGSTCNTCFDKAD-NCLSCPKNHVLDLSSCLDHECPNGTFYDTQLNECRHCPHNCMTCESVSSCSQCGLDHFLTGSGKCSANCQGNEYQTPNGLCLACNRSCEACMGPHSNECLSCRVGKYLSTTGECLEECLHGFVDKNSQCQACHSSCLACTGPSLFQCSTCPSGTKLGPQANCLSCEPRKFHDAHSDECLACHESCGTCSGPQDNHCLSCSLPLVLDTWNTTCVPCCE------SSDEKHCCSCTPSRDKCLQPSKKMLSRKRSSVRFG---LGDEALTNPSRSLFHYGSLLAILALMTLVIV 1337
L++ C++ CP N + C PCHESC TC G C C C+ CP GY D C PC C TCS C C+ + A CP ++T C CHESC TC G TQC C T+ + +CV CP Y D +EC+ CP GC TC++ C+ C+ W N+K C P + +C G F A+ C C C++C+ + + +CL+CP ++L C+ EC G Y + C C H C C S +C+ C L SG C +C + Y G C C SC C+GP ++C SC G L+ GEC EC GF C+ CH C C G C +CP L C+ C +++DA S C +C SC TCSGP C +CS PL +D N CVPCC S+ CC C P +C+ S ++ KR +G A PS ++ A + L V+V
Sbjct: 726 LDDSCVSRCPPRSYAN-QGGVCWPCHESCETCVGPGQDSCLTCAPAHLLVADLAVCLQQCPDGYWEDSEASVCRPCAAHCATCSERADGCTSCEHHLVLHDGT------CMASCPPSHYETEDDMCAKCHESCDTCQGPGETQCVTCHPSTYALDGRCVTSCPPAYYADKKRKECMRCPVGCSTCTS-AFCLSCEPKWEL-NKKGKCMPVGSDKCSAGEF--AVDQKCKRCNPACDSCYGENEGHCLTCPNPNLLQDYKCVP-ECSKG--YYAEAGRCARCMHGCSDCVSRLNCTSCASTLRLQ-SGACRTSC-ADGYYADRGTCSKCYLSCRTCIGPRRDQCASCPEGWRLAA-GECHPECPQGFYQSPGGCRHCHHYCRECDGSGPLHCKSCPPRFMLD-GGLCMECLGSQYYDATSGTCRSCDASCRTCSGPGQFSCTTCSRPLRIDRLNNQCVPCCSERGVTNSTPPTDCCHCNPENGECINSS---VAGKRRIAEWGALHTAPSADAAPSVAVVTIAVCAAAVGLFITVLV 1240
BLAST of endoprotease furin vs. nr
Match: gi|943946371|ref|XP_014356358.1| (PREDICTED: furin-like protease 2 [Papilio machaon]) HSP 1 Score: 1004.59 bits (2596), Expect = 0.000e+0 Identity = 556/1180 (47.12%), Postives = 697/1180 (59.07%), Query Frame = 0
Query: 15 GHGKIYHNHFALHIPEGEAKANRIALNLGFKNRGPIGTLSNHFLFEHEFLRPRCTNHSLEHHEILIKEPGVHWFEQQHERRRFKRD-------------------------LSDSMYISDPLFKDQWFLNHGAFDGSDMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMPQDNSDNKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDGLVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSISSASQGGKKPWYLEECSSTLASTYSSGTPGHDASIATVDQDARLRPDKICTTSHTGTSASAPIAAGVCALALEANPNLTWRDMQHIVVITSNPAPLLRESGWRVNAVGRKYSHKFGYGLMDASAMVEVAKVWPGSGRQAICETDTLSLDLPIPVNSGSVARVTLKTDACSGTKKEIRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSLLLPRPRDMTNGGFEDWPFLSVHFWGEPANGTWTLEVNHSPSVKSTSGLAKGIVKKWKMLFYGTRKSPLR-QSQLVSEFGPLPSEDFGDGLPGKMMDGSPEDGHNVSPNNNGQHVS--WSSGSFSTRAHS---GGILEHNKGQSGLLDYESPSS--SCHPQCEGNRCSGPKSTECYSCQNFKFGNVCVEHCPLTTYVSLRGTCQACHSSCQTCSGPNPNQCLTCSKSLFLLSDQSRCIKDQCPSGYRQRPSLNECVPCPYHCESCTETSEGVVNLIEGPRSGSLGIGETTLVCLKCQKGLVRSVLENKCLNGCPFGFSLNPETRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGS-FKTRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFSKALGGLCAPCGSTCNTCFD-KADNCLSCPKNHVLDLSSCLDHECPNGTFYDTQLNECRHCPHNCMTCESVSS--CSQCGLDHFLTGSGKCSANCQGNEYQTPN-GLCLACNRSCEACMGPHSNECLSC 1156
H YHN FA+H+P GE IA G+ N G IG+L ++L H + R S EHH L EP V WF+QQ ERRR KRD L+ + + DPLFK+QW+LN GA DG DMNV PAW KGYTGK VVV+ILDDGIQT+HPDL +NYDP ASTDINGND+DPMPQDN DNKHGTRCAGEVA A+N CGVGIAYNASIGGVRMLDG+VNDAVEARAL LNP+HIDIYSASWGPEDDGKTVDGPGPLA++AFI GV GR GKGSIFVWASGNGGR D+CNCDGYTNSIFTLSISSA+QGG KPWYLEECSSTLA+TYSSGTPGHD S+ATVD D RLRPD ICT HTGTSASAP+AAG+CALALEANP LTWRDMQ++VV+TS P PL +E+GW +N V RK SHKFGYGLMDAS MV +A+ W Q IC++ ++ D I + G V + + CS T E+RYLEHVQCKISL + PRG L I+LTSP GT S+LL RPRD+ + F+DWPFLSVHFWGE A G WTL + ++ + G++KKW+++FYGT P+R + + S P F D + + +N N Q+ +++GS +A + G + G++ L D C P+C+ C G T+C +C++++ + CV CP ++ + C CH SC+TC GP + CLTC+ + L++D + C++ QCP GY + + C PC HC +C++ ++ C C+ LV + CL CP + E SC CH SC TC G TQC C ++ E +CV CP+GY D +EC+ CP GC TC + C+ C A W N+K C + +C G F +C+ CH +C +C G+ T C C +KCVP+C GY + C C GC C + C C + AC C +G ++ G CA C +C TC + D C SCP L C ECP G FY + + CR C H C C+ C C F+ G C C G++Y P+ G+CL+C+ SC C GP C C
Sbjct: 20 AHDATYHNQFAVHVPNGERHVRDIAKRHGYVNHGQIGSLKGYYLLSHHEVHKRSAEPSHEHHRKLNDEPEVRWFQQQRERRRVKRDYTQRDAGLWSQFSRRMPSHRTRHRALNPTPFFPDPLFKEQWYLNGGAKDGLDMNVAPAWQKGYTGKGVVVSILDDGIQTNHPDLAQNYDPNASTDINGNDDDPMPQDNGDNKHGTRCAGEVAGVAYNQYCGVGIAYNASIGGVRMLDGVVNDAVEARALGLNPDHIDIYSASWGPEDDGKTVDGPGPLARRAFIYGVTSGRRGKGSIFVWASGNGGRHTDSCNCDGYTNSIFTLSISSATQGGYKPWYLEECSSTLATTYSSGTPGHDKSVATVDMDGRLRPDHICTVEHTGTSASAPLAAGICALALEANPELTWRDMQYLVVLTSRPQPLEKETGWIINGVKRKVSHKFGYGLMDASEMVSLAEQWVSVPPQHICKSQEINEDRSIDSSYGYTLSVHMDVNGCSATVNEVRYLEHVQCKISLRFFPRGNLRILLTSPMGTTSTLLFERPRDVVSSNFDDWPFLSVHFWGERAEGRWTLHIVNAGNRHVNQ---PGVLKKWQLIFYGTSVEPVRLKGKRPSAIAP----PFAFPTAADGYDSAGDSFYNTDAFANYQNFPSLFAAGSDPEKAIAQLDGHNVPSPHGENVLADSNDKRVMHECDPECDTQGCYGKGPTQCIACKHYRLDDACVSRCPPRSFANQGAVCWPCHESCETCVGPGQDSCLTCAPAHLLVADLAVCLQ-QCPDGYWEDSESSVCRPCAAHCSTCSDKADS---------------------CTSCEHHLV--LHNGTCLASCPPSY-FETEDYSCAKCHSSCDTCEGPAETQCVTCHPSSYSLEGRCVNACPSGYYADKKRKECMKCPVGCSTCIS-TFCMSCDANWEL-NKKGKCIQTGSDKCSSGEYFDGANCNRCHTACDSCYGDEDTNCLTCPSPNLLENYKCVPECSRGYYSE--SGRCTRCVHGCSACVSRLNCTACAGALRL--QSGAC----RTSCADGYYADR--GTCAKCYLSCRTCIGPRRDQCASCPSGWRLAAGEC-HPECPQG-FYQS-VGGCRRCHHYCRECDGSGPLHCRSCP-PRFMLDGGLC-MECLGSQYYEPSTGVCLSCDNSCRTCSGPGRFSCSGC 1150 HSP 2 Score: 219.164 bits (557), Expect = 6.016e-54 Identity = 156/450 (34.67%), Postives = 206/450 (45.78%), Query Frame = 0
Query: 817 LENKCLNGCPFGFSLNPETRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEH--KCVPDCPAGYRPDVHHQECVPCPQGCHTCSND-QKCIKCQAGWSFANEKEACSPQANAQCPEGSFKTR--SCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFSKALGGLCAPCGSTCNTCF-DKADNCLSCPKNHVLDLSSCLDHECPNGTFYDTQLNECRHCPHNCMTCESVSSCSQCGLDHFLTGSGKCSANCQGNEYQTPNGLCLACNRSCEACMGPHSNECLSCRVGKYLSTTGECLEECLHGFVDKNSQCQACHSSCLACTGPSLFQCSTCPSGTKLGPQANCLSCEPRKFHDAHSDECLACHESCGTCSGPQDNHCLSCSLPLVLD 1260
L++ C++ CP S + C PCHESC TC G C C C+ CP GY D C PC C TCS+ C C+ N A CP F+T SC CH SC TC G TQC C ++ E +CV CP+GY D +EC+ CP GC TC + C+ C A W N+K C + +C G + G C C + C++C+ D+ NCL+CP ++L+ C+ EC G Y ++ C C H C C S +C+ C L SG C +C + Y G C C SC C+GP ++C SC G L+ GEC EC GF C+ CH C C G C +CP L C+ C ++++ + CL+C SC TCSGP C CS PL LD
Sbjct: 726 LDDACVSRCP-PRSFANQGAVCWPCHESCETCVGPGQDSCLTCAPAHLLVADLAVCLQQCPDGYWEDSESSVCRPCAAHCSTCSDKADSCTSCEHHLVLHNGT------CLASCPPSYFETEDYSCAKCHSSCDTCEGPAETQCVTCHPSSYSLEGRCVNACPSGYYADKKRKECMKCPVGCSTCIS-TFCMSCDANWEL-NKKGKCIQTGSDKCSSGEYFD--GANCNRCHTACDSCYGDEDTNCLTCPSPNLLENYKCVP-ECSRG--YYSESGRCTRCVHGCSACVSRLNCTACAGALRLQ-SGACRTSC-ADGYYADRGTCAKCYLSCRTCIGPRRDQCASCPSGWRLAA-GECHPECPQGFYQSVGGCRRCHHYCRECDGSGPLHCRSCPPRFMLD-GGLCMECLGSQYYEPSTGVCLSCDNSCRTCSGPGRFSCSGCSRPLRLD 1157 HSP 3 Score: 119.783 bits (299), Expect = 2.665e-23 Identity = 85/258 (32.95%), Postives = 133/258 (51.55%), Query Frame = 0
Query: 1024 AQCPEGSFSKALGGLCAPCGSTCNTCFDKA-DNCLSCPKNHVL--DLSSCLDHECPNGTFYDTQLNECRHCPHNCMTC-ESVSSCSQCGLDHFLTGSGKCSANCQGNEYQTPNGLCLACNRSCEACMGPHSNECLSCRVGKYLSTTGECLEECLHGFV--DKNSQCQACHSSCLACTGPSLFQCSTCPSGTKLGPQANCL-----SCEPRKFHDAHSDECLACHESCGTCSGPQDNHCLSCSLPLVLDTWNTTCVPCC 1270
++CP SF+ G +C PC +C TC D+CL+C H+L DL+ CL +CP+G + D++ + CR C +C TC + SC+ C H + +G C A+C + ++T + C C+ SC+ C GP +C++C Y S G C+ C G+ K +C C C C S F C +C + +L + C+ C ++ D + C CH +C +C G +D +CL+C P +L+ N CVP C
Sbjct: 732 SRCPPRSFANQ-GAVCWPCHESCETCVGPGQDSCLTCAPAHLLVADLAVCL-QQCPDGYWEDSESSVCRPCAAHCSTCSDKADSCTSCE-HHLVLHNGTCLASCPPSYFETEDYSCAKCHSSCDTCEGPAETQCVTCHPSSY-SLEGRCVNACPSGYYADKKRKECMKCPVGCSTCI--STF-CMSCDANWELNKKGKCIQTGSDKCSSGEYFDGAN--CNRCHTACDSCYGDEDTNCLTCPSPNLLE--NYKCVPEC 978
BLAST of endoprotease furin vs. nr
Match: gi|1247045798|gb|PCG80179.1| (hypothetical protein B5V51_10545 [Heliothis virescens]) HSP 1 Score: 1003.05 bits (2592), Expect = 0.000e+0 Identity = 554/1178 (47.03%), Postives = 695/1178 (59.00%), Query Frame = 0
Query: 19 IYHNHFALHIPEGEAKANRIALNLGFKNRGPIGTLSNHFLFEHEFLRPRCTNHSLEHHEILIKEPGVHWFEQQHERRRFKRD-------------------------LSDSMYISDPLFKDQWFLNHGAFDGSDMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMPQDNSDNKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDGLVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSISSASQGGKKPWYLEECSSTLASTYSSGTPGHDASIATVDQDARLRPDKICTTSHTGTSASAPIAAGVCALALEANPNLTWRDMQHIVVITSNPAPLLRESGWRVNAVGRKYSHKFGYGLMDASAMVEVAKVWPGSGRQAICETDTLSLDLPIPVNSGSVARVTLKTDACSGTKKEIRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSLLLPRPRDMTNGGFEDWPFLSVHFWGEPANGTWTLEVNHSPSVKSTSGLAKGIVKKWKMLFYGTRKSPLR-QSQLVSEFGP---LPS-----EDFGDGLPGKMMDGSPEDGHNV--SPNNNGQHVSWSSGSFSTRAHSGGILEHNKGQSGLLDYESPSSSCHPQCEGNRCSGPKSTECYSCQNFKFGNVCVEHCPLTTYVSLRGTCQACHSSCQTCSGPNPNQCLTCSKSLFLLSDQSRCIKDQCPSGYRQRPSLNECVPCPYHCESCTETSEGVVNLIEGPRSGSLGIGETTLVCLKCQKGLVRSVLENKCLNGCPFGFSLNPETRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSF-KTRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFSKALGGLCAPCGSTCNTCFD-KADNCLSCPKNHVLDLSSCLDHECPNGTFYDTQLNECRHCPHNCMTCESVSS--CSQCGLDHFLTGSGKCSANCQGNEYQTPNGLCLACNRSCEACMGPHSNECLSC 1156
+YH+ FA+H+P G + IA GF N G IG+L N++L H +R R S EHH+ L EP V WFEQQ E+RR KRD LS S + DPLFK+QW+LN GA DG DMNV PAW KGYTGK VVV+ILDDGIQT+HPDL +NYDP ASTDINGND+DPMPQDN DNKHGTRCAGEVAA A+N CGVGIAYNASIGGVRMLDG+VNDAVEARAL LNP+HIDIYSASWGPEDDGKTVDGPGPLA++AFI GV GR GKGSIFVWASGNGGR D+CNCDGYTNSIFTLSISSA+QGG KPWYLEECSSTLA+TYSSGTPGHD S+ATVD D RLR D ICT HTGTSASAP+AAG+CALALEANP LTWRDMQ++VV+TS P PL +E GW +N V RK SHKFGYGLMDAS MV +A+ W Q IC++ ++ D I G + + CS T E+RYLEHVQCKISL + PRG L I+LTSP GT S+LL RPRD+ + F+DWPFLSVHFWGE A G WTL++ ++ + GI+KKW+++FYGT P+R +++ S P P+ E GD + ++ N+ + ++ + V+ G H +L + + + D C P+C+ C G +C +C++++ + CV CP +Y + G C CH SC+TC GP + CLTC+ + L++D + C++ QCP GY + + C PC HC +C+E ++G C C+ LV + + CL CP E C CHESC +C G QC C T+ + KCV CP Y D +EC+ CP GC TC++ C+ C++ W N+K C P +C G F + + C C+ +C +C G C C + E+KCV +C GY P+ C C GC C + C C + + AC C +G ++ G C+ C +C TC + D C SCP L C ECP G FY + L CRHC H C C+ C C F+ G C Y +G C AC+ SC C GP C +C
Sbjct: 24 VYHDQFAVHVPAGPHHVDDIARRHGFVNHGQIGSLKNYYLLSHHEVRKRSAEPSHEHHKKLNDEPQVRWFEQQREKRRIKRDYSPYDRAAFSQLSRRLQPHRPHYRALSSSPFFPDPLFKEQWYLNGGAKDGLDMNVAPAWQKGYTGKGVVVSILDDGIQTNHPDLAQNYDPNASTDINGNDDDPMPQDNGDNKHGTRCAGEVAAVAYNQYCGVGIAYNASIGGVRMLDGVVNDAVEARALGLNPDHIDIYSASWGPEDDGKTVDGPGPLARRAFIYGVTSGRRGKGSIFVWASGNGGRHTDSCNCDGYTNSIFTLSISSATQGGYKPWYLEECSSTLATTYSSGTPGHDKSVATVDMDGRLRSDHICTVEHTGTSASAPLAAGICALALEANPELTWRDMQYLVVMTSRPQPLEKEGGWIINGVKRKVSHKFGYGLMDASEMVSLAEQWISVPPQHICKSQEINEDKSIESTFGYTLATHMDVNGCSSTVNEVRYLEHVQCKISLRFFPRGNLRILLTSPMGTVSTLLFERPRDVVSSNFDDWPFLSVHFWGEHAEGRWTLQIVNAGNRHVNQA---GILKKWQLIFYGTAIDPVRLRTKRPSPVAPPFAFPTAADGYETIGDSFYNTDAFANYQNFPNLFAAGSDPEKAVARLDGHNVPSPHGENVLADSNDKRVMHD-------CDPECDSQGCYGKGPIQCIACKHYRLDDSCVSRCPPRSYANQGGVCWPCHESCETCVGPGQDSCLTCAPAHLLVADLAVCLQ-QCPDGYWEDSEASVCRPCAAHCATCSERADG---------------------CTSCEHHLV--LHDGTCLASCPSSH-YETEDYMCAKCHESCDSCQGPGEAQCVTCHPSTYALDGKCVTSCPPAYYADKKRKECMRCPVGCLTCTS-AFCLSCESNWEL-NKKGKCLPVGTEKCNSGEFAEDQKCKRCNGACDSCYGENDGHCLTCQNPNLLEEYKCVSECSRGYYPEA--GRCARCMHGCSECVSRLNCTACVSALRL--QSGAC----RTACADGYYADR--GTCSKCYLSCRTCIGPRRDQCASCPDGWRLAAGEC-HPECPQG-FYQS-LGGCRHCHHYCRECDGSGPLHCKSCP-PRFMLDGGLCMECLGSQYYDASSGTCRACDGSCRTCSGPGQFSCTTC 1150 HSP 2 Score: 232.261 bits (591), Expect = 5.203e-58 Identity = 171/520 (32.88%), Postives = 232/520 (44.62%), Query Frame = 0
Query: 799 GETTLVCLKCQKGLVRSVLENKCLNGCPFGFSLNPETRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEH--KCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQK-CIKCQAGWSFANEKEACSPQANAQCPEGSFKTRS--CDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFSKALGGLCAPCGSTCNTCFDKAD-NCLSCPKNHVLDLSSCLDHECPNGTFYDTQLNECRHCPHNCMTCESVSSCSQCGLDHFLTGSGKCSANCQGNEYQTPNGLCLACNRSCEACMGPHSNECLSCRVGKYLSTTGECLEECLHGFVDKNSQCQACHSSCLACTGPSLFQCSTCPSGTKLGPQANCLSCEPRKFHDAHSDECLACHESCGTCSGPQDNHCLSCSLPLVLDTWNTTCVPCC------ESSDEKHCCSCTPSRDKCLQPSKKMLSRKRSSVRFG 1306
G+ + C+ C+ L++ C++ CP N + C PCHESC TC G C C C+ CP GY D C PC C TCS C C+ + A CP ++T C CHESC +C G QC C T+ + KCV CP Y D +EC+ CP GC TC++ C+ C++ W N+K C P +C G F++ C C C++C+ + D +CL+C ++L+ C+ EC G Y + C C H C C S +C+ C + SG C C + Y G C C SC C+GP ++C SC G L+ GEC EC GF C+ CH C C G C +CP L C+ C +++DA S C AC SC TCSGP C +CS PL LD N CVPCC S+ CC+C P +C+ S ++ KR +G
Sbjct: 712 GKGPIQCIACK----HYRLDDSCVSRCPPRSYAN-QGGVCWPCHESCETCVGPGQDSCLTCAPAHLLVADLAVCLQQCPDGYWEDSEASVCRPCAAHCATCSERADGCTSCEHHLVLHDGT------CLASCPSSHYETEDYMCAKCHESCDSCQGPGEAQCVTCHPSTYALDGKCVTSCPPAYYADKKRKECMRCPVGCLTCTS-AFCLSCESNWEL-NKKGKCLPVGTEKCNSGEFAEDQK--CKRCNGACDSCYGENDGHCLTCQNPNLLEEYKCVS-ECSRG--YYPEAGRCARCMHGCSECVSRLNCTAC-VSALRLQSGACRTAC-ADGYYADRGTCSKCYLSCRTCIGPRRDQCASCPDGWRLAA-GECHPECPQGFYQSLGGCRHCHHYCRECDGSGPLHCKSCPPRFMLD-GGLCMECLGSQYYDASSGTCRACDGSCRTCSGPGQFSCTTCSRPLRLDRLNNQCVPCCSERGATNSTPATDCCNCNPDTGECINSS---VAGKRRIAEWG 1206
BLAST of endoprotease furin vs. nr
Match: gi|1199375267|ref|XP_021181870.1| (furin-like protease 2 [Helicoverpa armigera]) HSP 1 Score: 1001.5 bits (2588), Expect = 0.000e+0 Identity = 553/1178 (46.94%), Postives = 695/1178 (59.00%), Query Frame = 0
Query: 19 IYHNHFALHIPEGEAKANRIALNLGFKNRGPIGTLSNHFLFEHEFLRPRCTNHSLEHHEILIKEPGVHWFEQQHERRRFKRD-------------------------LSDSMYISDPLFKDQWFLNHGAFDGSDMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMPQDNSDNKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDGLVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSISSASQGGKKPWYLEECSSTLASTYSSGTPGHDASIATVDQDARLRPDKICTTSHTGTSASAPIAAGVCALALEANPNLTWRDMQHIVVITSNPAPLLRESGWRVNAVGRKYSHKFGYGLMDASAMVEVAKVWPGSGRQAICETDTLSLDLPIPVNSGSVARVTLKTDACSGTKKEIRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSLLLPRPRDMTNGGFEDWPFLSVHFWGEPANGTWTLEVNHSPSVKSTSGLAKGIVKKWKMLFYGTRKSPLR-QSQLVSEFGP---LPS-----EDFGDGLPGKMMDGSPEDGHNV--SPNNNGQHVSWSSGSFSTRAHSGGILEHNKGQSGLLDYESPSSSCHPQCEGNRCSGPKSTECYSCQNFKFGNVCVEHCPLTTYVSLRGTCQACHSSCQTCSGPNPNQCLTCSKSLFLLSDQSRCIKDQCPSGYRQRPSLNECVPCPYHCESCTETSEGVVNLIEGPRSGSLGIGETTLVCLKCQKGLVRSVLENKCLNGCPFGFSLNPETRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSF-KTRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFSKALGGLCAPCGSTCNTCFD-KADNCLSCPKNHVLDLSSCLDHECPNGTFYDTQLNECRHCPHNCMTCESVSS--CSQCGLDHFLTGSGKCSANCQGNEYQTPNGLCLACNRSCEACMGPHSNECLSC 1156
+YH+ FA+H+P G + IA GF N G IG+L +++L H +R R S EHH+ L EP V WFEQQ E+RR KRD L+ S + DPLFK+QW+LN GA DG DMNV PAW KGYTGK VVV+ILDDGIQT+HPDL +NYD ASTDINGND+DPMPQDN DNKHGTRCAGEVAA A+N CGVGIAYNASIGGVRMLDG+VNDAVEARAL LNP+HIDIYSASWGPEDDGKTVDGPGPLA++AFI GV GR GKGSIFVWASGNGGR D+CNCDGYTNSIFTLSISSA+QGG KPWYLEECSSTLA+TYSSGTPGHD S+ATVD D RLR D ICT HTGTSASAP+AAG+CALALEANP LTWRDMQ++VV+TS P PL +E GW +N V RK SHKFGYGLMDAS MV +A+ W Q IC++ ++ D PI G + + CS T E+RYLEHVQCKISL + PRG L I+LTSP GT S+LL RPRD+ + F+DWPFLSVHFWGE A G WTL++ ++ + GI+KKW+++FYGT P+R +++ S P P+ E GD + ++ N+ + ++ + V+ G H +L + + + D C P+C+ C G +C +C++++ + CV CP +Y + G C CH SC+TC GP + CLTC+ + L++D + C++ QCP GY + + C PC HC +C+E ++G C C+ LV + + CL CP E C CHESC +C G QC C T+ + KCV CP Y D +EC+ CP GC TC++ C+ C+ W N+K C P +C G F + + C C+E+C +C G C C + E+KCV +C GY P+ C C GC C + C C + + AC C +G ++ G C+ C +C TC + D C SCP L C ECP G FY + L CRHC H C C+ C C F+ G C Y +G C AC+ SC C GP C +C
Sbjct: 24 VYHDQFAVHVPAGPHHVDDIARRHGFVNHGQIGSLKHYYLLSHHEVRKRSAEPSHEHHKKLNDEPQVRWFEQQREKRRTKRDYSPYDRAAFSQLSRRLQPHRPHYRALTSSPFFPDPLFKEQWYLNGGAKDGLDMNVAPAWQKGYTGKGVVVSILDDGIQTNHPDLAQNYDANASTDINGNDDDPMPQDNGDNKHGTRCAGEVAAVAYNQYCGVGIAYNASIGGVRMLDGVVNDAVEARALGLNPDHIDIYSASWGPEDDGKTVDGPGPLARRAFIYGVTSGRRGKGSIFVWASGNGGRHTDSCNCDGYTNSIFTLSISSATQGGYKPWYLEECSSTLATTYSSGTPGHDKSVATVDMDGRLRSDHICTVEHTGTSASAPLAAGICALALEANPELTWRDMQYLVVMTSRPQPLEKEGGWIINGVKRKVSHKFGYGLMDASEMVSLAEQWISVPPQHICKSQEINEDKPIESTFGYTLATHMDVNGCSSTVNEVRYLEHVQCKISLRFFPRGNLRILLTSPMGTVSTLLFERPRDVVSSNFDDWPFLSVHFWGEHAEGRWTLQIVNAGNRHVNQA---GILKKWQLIFYGTAIDPVRLRTKRPSPIAPPFAFPTAADGYETIGDSFYNTDAFANYQNFPNLFAAGSDPEKAVARLDGHNVPSPHGENVLADSNDKRVMHD-------CDPECDSQGCYGKGPIQCIACKHYRLDDSCVSRCPPRSYANQGGVCWPCHESCETCVGPGQDSCLTCAPAHLLVADLAVCLQ-QCPDGYWEDSESSVCRPCAAHCATCSERADG---------------------CTSCEHHLV--LHDGTCLASCPPSH-YETEDYMCAKCHESCDSCQGPGEAQCVTCHPSTYALDGKCVTSCPPAYYADKKRKECMRCPVGCSTCTS-AFCLSCEPNWEL-NKKGKCMPVGTEKCSSGEFAEAQKCKRCNEACDSCYGENDGHCLTCQNPNLLEEYKCVSECSRGYYPEA--GRCARCMHGCSECVSRLNCTACVSALRL--QSGAC----RTACADGYYADR--GTCSKCYLSCRTCIGPRRDQCASCPDGWRLAAGEC-HPECPQG-FYQS-LGGCRHCHHYCRECDGSGPLHCKSCP-PRFMLDGGLCMECLGSQYYDASSGTCRACDGSCRTCSGPGQFSCTTC 1150 HSP 2 Score: 234.958 bits (598), Expect = 7.319e-59 Identity = 172/520 (33.08%), Postives = 232/520 (44.62%), Query Frame = 0
Query: 799 GETTLVCLKCQKGLVRSVLENKCLNGCPFGFSLNPETRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEH--KCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQK-CIKCQAGWSFANEKEACSPQANAQCPEGSFKTRS--CDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFSKALGGLCAPCGSTCNTCFDKAD-NCLSCPKNHVLDLSSCLDHECPNGTFYDTQLNECRHCPHNCMTCESVSSCSQCGLDHFLTGSGKCSANCQGNEYQTPNGLCLACNRSCEACMGPHSNECLSCRVGKYLSTTGECLEECLHGFVDKNSQCQACHSSCLACTGPSLFQCSTCPSGTKLGPQANCLSCEPRKFHDAHSDECLACHESCGTCSGPQDNHCLSCSLPLVLDTWNTTCVPCCE------SSDEKHCCSCTPSRDKCLQPSKKMLSRKRSSVRFG 1306
G+ + C+ C+ L++ C++ CP N + C PCHESC TC G C C C+ CP GY D C PC C TCS C C+ + A CP ++T C CHESC +C G QC C T+ + KCV CP Y D +EC+ CP GC TC++ C+ C+ W N+K C P +C G F++A C C C++C+ + D +CL+C ++L+ C+ EC G Y + C C H C C S +C+ C + SG C C + Y G C C SC C+GP ++C SC G L+ GEC EC GF C+ CH C C G C +CP L C+ C +++DA S C AC SC TCSGP C +CS PL LD N CVPCC S+ CC+C P +C+ S ++ KR +G
Sbjct: 712 GKGPIQCIACK----HYRLDDSCVSRCPPRSYAN-QGGVCWPCHESCETCVGPGQDSCLTCAPAHLLVADLAVCLQQCPDGYWEDSESSVCRPCAAHCATCSERADGCTSCEHHLVLHDGT------CLASCPPSHYETEDYMCAKCHESCDSCQGPGEAQCVTCHPSTYALDGKCVTSCPPAYYADKKRKECMRCPVGCSTCTS-AFCLSCEPNWEL-NKKGKCMPVGTEKCSSGEFAEAQK--CKRCNEACDSCYGENDGHCLTCQNPNLLEEYKCVS-ECSRG--YYPEAGRCARCMHGCSECVSRLNCTAC-VSALRLQSGACRTAC-ADGYYADRGTCSKCYLSCRTCIGPRRDQCASCPDGWRLAA-GECHPECPQGFYQSLGGCRHCHHYCRECDGSGPLHCKSCPPRFMLD-GGLCMECLGSQYYDASSGTCRACDGSCRTCSGPGQFSCTTCSRPLRLDRLNNQCVPCCSERGATNSTPASDCCNCNPDTGECINSS---VAGKRRIAEWG 1206
BLAST of endoprotease furin vs. nr
Match: gi|910332957|ref|XP_013169849.1| (PREDICTED: furin-like protease 2 [Papilio xuthus] >gi|910332959|ref|XP_013169850.1| PREDICTED: furin-like protease 2 [Papilio xuthus]) HSP 1 Score: 996.497 bits (2575), Expect = 0.000e+0 Identity = 561/1211 (46.33%), Postives = 706/1211 (58.30%), Query Frame = 0
Query: 15 GHGKIYHNHFALHIPEGEAKANRIALNLGFKNRGPIGTLSNHFLFEHEFLRPRCTNHSLEHHEILIKEPGVHWFEQQHERRRFKRD-------------------------LSDSMYISDPLFKDQWFLNHGAFDGSDMNVQPAWAKGYTGKRVVVTILDDGIQTDHPDLRRNYDPLASTDINGNDEDPMPQDNSDNKHGTRCAGEVAAEAFNGICGVGIAYNASIGGVRMLDGLVNDAVEARALSLNPNHIDIYSASWGPEDDGKTVDGPGPLAKKAFINGVKFGRDGKGSIFVWASGNGGRKVDNCNCDGYTNSIFTLSISSASQGGKKPWYLEECSSTLASTYSSGTPGHDASIATVDQDARLRPDKICTTSHTGTSASAPIAAGVCALALEANPNLTWRDMQHIVVITSNPAPLLRESGWRVNAVGRKYSHKFGYGLMDASAMVEVAKVWPGSGRQAICETDTLSLDLPIPVNSGSVARVTLKTDACSGTKKEIRYLEHVQCKISLHYHPRGALHIVLTSPSGTKSSLLLPRPRDMTNGGFEDWPFLSVHFWGEPANGTWTLEVNHSPSVKSTSGLAKGIVKKWKMLFYGTRKSPLR-QSQLVSEFGPLPSEDFGDGLPGKMMDGSPEDGHNVSPNNNGQHVS--WSSGSFSTRAHS---GGILEHNKGQSGLLDYESPSS--SCHPQCEGNRCSGPKSTECYSCQNFKFGNVCVEHCPLTTYVSLRGTCQACHSSCQTCSGPNPNQCLTCSKSLFLLSDQSRCIKDQCPSGYRQRPSLNECVPCPYHCESCTETSEGVVNLIEGPRSGSLGIGETTLVCLKCQKGLVRSVLENKCLNGCPFGFSLNPETRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGS-FKTRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFSKALGGLCAPCGSTCNTCFD-KADNCLSCPKNHVLDLSSCLDHECPNGTFYDTQLNECRHCPHNCMTCESVSS--CSQCGLDHFLTGSGKCSANCQGNEYQTP-NGLCLACNRSCEACMGPHSNECLSC-RVGKYLSTTGECLEECLHGFVDKNSQCQAC 1186
H YHN FA+H+P GE + IA G+ N G IG+L ++L H + R S EHH L EP V WF+QQ ERRR KRD L+ + + DPLFK+QW+LN GA DG DMNV PAW KGYTGK VVV+ILDDGIQT+HPDL +NYD ASTDINGND+DPMPQDN DNKHGTRCAGEVA A+N CGVGIAYNASIGGVRMLDG+VNDAVEARAL LNP+HIDIYSASWGPEDDGKTVDGPGPLA++AFI GV GR GKGSIFVWASGNGGR D+CNCDGYTNSIFTLSISSA+QGG KPWYLEECSSTLA+TYSSGTPGHD S+ATVD D RLRPD ICT HTGTSASAP+AAG+CALALEANP LTWRDMQ++VV+TS P PL +E+GW +N V RK SHKFGYGLMDAS MV +A+ W Q IC++ ++ D I + G V + + CS T E+RYLEHVQCKISL + PRG L I+LTSP GT S+LL RPRD+ + F+DWPFLSVHFWGE A G WTL + ++ + G++KKW+++FYGT P+R + + S P F D + + +N N Q+ +++GS +A + G + G++ L D C P+C+ C G T+C +C++++ + CV CP ++ + C CH SC+TC GP + CLTC+ + L++D + C++ QCP GY + + C PC HC +C++ ++ C C+ LV + CL CP + E SC CH SC TC G TQC C +F E +CV CP+GY D +EC+ CP GC TC + C+ C A W N+K C + +C G F SC+ C+ +C +C G+ T C C +KCV +C GY + C C GC C + C C + AC C +G ++ G CA C +C TC + D C SCP L C ECP G FY + + CR C H C C+ C C F+ G C C G++Y P +G+CL+C+ +C C GP C C R + +C+ C V NS C
Sbjct: 23 AHDATYHNQFAVHVPNGERHVHDIAKRHGYVNHGQIGSLKGYYLLSHHEVHKRSAEPSHEHHRKLNDEPEVRWFQQQRERRRVKRDYTQRDAGLWSQFSRRMPSHRTRHRALNPTPFFPDPLFKEQWYLNGGAKDGLDMNVAPAWQKGYTGKGVVVSILDDGIQTNHPDLAQNYDANASTDINGNDDDPMPQDNGDNKHGTRCAGEVAGVAYNQYCGVGIAYNASIGGVRMLDGVVNDAVEARALGLNPDHIDIYSASWGPEDDGKTVDGPGPLARRAFIYGVTSGRRGKGSIFVWASGNGGRHTDSCNCDGYTNSIFTLSISSATQGGYKPWYLEECSSTLATTYSSGTPGHDKSVATVDMDGRLRPDHICTVEHTGTSASAPLAAGICALALEANPELTWRDMQYLVVLTSRPQPLEKETGWIINGVKRKVSHKFGYGLMDASEMVSLAEQWVSVPPQHICKSQEINEDKSIDSSYGYTLSVHMDVNGCSATVNEVRYLEHVQCKISLRFFPRGNLRILLTSPMGTTSTLLFERPRDVVSSNFDDWPFLSVHFWGERAEGRWTLHIVNAGNRHVNQ---PGVLKKWQLIFYGTSVEPVRLRGKKPSAIAP----PFAFPTAADGYDSAGDSFYNTDAFANYQNFPSLFAAGSDPEKAIAQLDGHNVPSPHGENVLADSNDKRVMHECDPECDTQGCYGKGPTQCIACKHYRLDDACVSRCPPRSFANQGAVCWPCHESCETCVGPGQDSCLTCAPAHLLVADLAVCLQ-QCPDGYWEDSESSVCRPCAAHCSTCSDKADS---------------------CTSCEHHLV--LHNGTCLASCPPSY-FETEDYSCAKCHSSCDTCEGPAETQCVTCHPSSFSLEGRCVNACPSGYYADKKRKECMKCPVGCSTCIS-AFCMSCDANWEL-NKKGKCIQTGSDKCSSGEYFDGASCNRCNNACDSCYGDEDTNCLTCPAPNLLENYKCVAECSRGYFSE--SGRCTRCVHGCAACVSRLNCTACAGALRL--QSGAC----RTSCADGYYADR--GTCAKCYLSCRTCIGPRRDQCASCPSGWRLAAGEC-HPECPQG-FYQS-VGGCRRCHHYCRECDGSGPLHCLSCP-PRFMLDGGLC-MECLGSQYYEPSSGVCLSCDNTCRTCSGPGRFSCSGCSRPLRLDRLNNQCVPCCSERGVYANSSASDC 1184 HSP 2 Score: 236.884 bits (603), Expect = 1.808e-59 Identity = 172/502 (34.26%), Postives = 227/502 (45.22%), Query Frame = 0
Query: 817 LENKCLNGCPFGFSLNPETRSCDPCHESCATCTGNLSTQCSLCLDGTFYFEH--KCVPDCPAGYRPDVHHQECVPCPQGCHTCSND-QKCIKCQAGWSFANEKEACSPQANAQCPEGSFKTR--SCDPCHESCATCTGNLSTQCSLCLDGTFYFEHKCVPDCPAGYRPDVHHQECVPCPQGCHTCSNDQKCIKCQAGWSFANEKEACSPQANAQCPEGSFSKALGGLCAPCGSTCNTCF-DKADNCLSCPKNHVLDLSSCLDHECPNGTFYDTQLNECRHCPHNCMTCESVSSCSQCGLDHFLTGSGKCSANCQGNEYQTPNGLCLACNRSCEACMGPHSNECLSCRVGKYLSTTGECLEECLHGFVDKNSQCQACHSSCLACTGPSLFQCSTCPSGTKLGPQANCLSCEPRKFHDAHSDECLACHESCGTCSGPQDNHCLSCSLPLVLDTWNTTCVPCCE------SSDEKHCCSCTPSRDKCLQPSKKMLSRKRSSVRFG 1306
L++ C++ CP S + C PCHESC TC G C C C+ CP GY D C PC C TCS+ C C+ N A CP F+T SC CH SC TC G TQC C +F E +CV CP+GY D +EC+ CP GC TC + C+ C A W N+K C + +C G + G C C + C++C+ D+ NCL+CP ++L+ C+ EC G F ++ C C H C C S +C+ C L SG C +C + Y G C C SC C+GP ++C SC G L+ GEC EC GF C+ CH C C G C +CP L C+ C ++++ S CL+C +C TCSGP C CS PL LD N CVPCC +S CC C +C+ S ++ KR +G
Sbjct: 729 LDDACVSRCP-PRSFANQGAVCWPCHESCETCVGPGQDSCLTCAPAHLLVADLAVCLQQCPDGYWEDSESSVCRPCAAHCSTCSDKADSCTSCEHHLVLHNGT------CLASCPPSYFETEDYSCAKCHSSCDTCEGPAETQCVTCHPSSFSLEGRCVNACPSGYYADKKRKECMKCPVGCSTCIS-AFCMSCDANWEL-NKKGKCIQTGSDKCSSGEYFD--GASCNRCNNACDSCYGDEDTNCLTCPAPNLLENYKCVA-ECSRGYF--SESGRCTRCVHGCAACVSRLNCTACAGALRLQ-SGACRTSC-ADGYYADRGTCAKCYLSCRTCIGPRRDQCASCPSGWRLAA-GECHPECPQGFYQSVGGCRRCHHYCRECDGSGPLHCLSCPPRFMLD-GGLCMECLGSQYYEPSSGVCLSCDNTCRTCSGPGRFSCSGCSRPLRLDRLNNQCVPCCSERGVYANSSASDCCHCNMDTGECINSS---VAGKRRIAEWG 1209 The following BLAST results are available for this feature:
BLAST of endoprotease furin vs. L. salmonis genes
Analysis Date: 2018-04-19 (T. kinsejongensis vs L. Salmonis peptides) Total hits: 9
BLAST of endoprotease furin vs. SwissProt
Analysis Date: 2018-04-19 (T. kingejongensis peptided Blastp vs. SwissProt) Total hits: 25
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BLAST of endoprotease furin vs. nr
Analysis Date: 2018-05-15 (T. kingsejongensis proteins Blastp vs. NR) Total hits: 25
Pagesback to topAlignments
The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at scaffold298_size217389:6483..10828+ Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>snap_masked-scaffold298_size217389-processed-gene-0.1 ID=snap_masked-scaffold298_size217389-processed-gene-0.1|Name=endoprotease furin|organism=Tigriopus kingsejongensis|type=gene|length=4346bp|location=Sequence derived from alignment at scaffold298_size217389:6483..10828+ (Tigriopus kingsejongensis)back to top Synonyms
The feature 'endoprotease furin' has the following synonyms
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