Query:  101 VLTRLGKIRGRRSQTRNGRPIFSFRALPYGVPPLGELRFRPPLPVEPWAGSLDGAGRESPQCIQVSVLSPESK-MYLG-SEDCLYLNVFTPHLPGAGKRSLFPVMVFFHGGAFNVGSNDSRLYGPEYWLDY-GVVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCASTS-FLHNDRAPSVYGKAFARALGIDVAQSESDILECLQKVPIKSIMDKSTVFKDWDVTNPLPWKPIVDGQFAT--QPFLPQPFEDLIRSGFANKAIPVLSGYTSEEGLILSAFFHKSQRRWDLLFNQWEIWAPQLLFNRESDLVTKADQSCVSQIKEKFFPGEGFPARSESNLKRLEQLFSLAI---FQAPLRKDLDLLSEHGFSIFAYVFQYEGSM 530
            V+T LGK++G+ +   N + I+SF  +PY   P    RF    P   W G+LD   +ES    Q + +  ES  +Y G  +DCLYLNVFTP L       L PV+V+FHGGAF +G ND+++YGPE  L    +VLVTVN+R+GP GFLS +  D PGN G+ DQ+L+L W Q H+  FGG  +NVT++G+ AG MS+  HL SP+S+G FHK+I LSG    + F+H DR P  Y KAFA +LG++V QS  +IL  L+ +  K+I+ K+ +FKD  +    PWKP VDG + T    FLP  F +L+  G  N    +L GYT+++GL       +    W L+   W   AP L FNRE D VT+ D++ V ++   F+ GE      E N K    L  +A    F+ P      LL     S+  Y+ Q+  S+
Sbjct:   17 VITSLGKLKGK-TLLMNDKHIYSFTGVPYADKPQ---RFSLAKPCSKWTGTLD-CTKESKMGYQPNPMFFESTFLYHGFPDDCLYLNVFTPILK-EDSFDLLPVIVYFHGGAFILGGNDTKIYGPEILLSTQNMVLVTVNFRLGPFGFLSFQNSDCPGNQGMHDQILSLMWVQSHIHHFGGTSSNVTIMGQXAGGMSSLYHLASPLSKGLFHKIICLSGAVMYAPFVHIDRDPWDYAKAFAESLGVNVNQSVDNILTQLRSISAKTILSKTFLFKDVFLLASCPWKPCVDGGYLTPETSFLPDTFINLVSQGKGNPVESILMGYTAQDGLSSLIEVMRYPNIWGLIQKDWSQIAPILFFNRERDNVTEEDRTAVEKMHSMFY-GEEVVRPLEWNKKNFSTLVKMATMFSFKLPFYATAKLLHR---SVNQYIIQWLSSV 445          

Query:  106 GKIRG--RRSQTRNGRPIFSFRALPYGVPPLGELRFRPPLPV-EPWAGSLDGAGRESPQCIQVSVLSPESKMYLGSEDCLYLNVFTPHLPGAGKRSLFPVMVFFHGGAFNVGSNDSRLYGPEYWLDYGVVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMS-RGFFHKVIALSGCA-STSFLHNDRAPSVYGKAFARALGIDVAQSESDILECLQKVPIKSIMDKSTVFKDWD-VTNPLPWKPIVDGQFATQPFLPQPFEDLIRSGFANKAIPVLSGYTSEEG-LILSAFFHKSQRRWDLLFNQWEIWAPQLLFNRESDLVTKADQSCVSQIKEKFFPGEGFPARSESNLKRLEQLFSLAIFQAPLRKDLDLLSEHGFSIFAYVFQYEGSMSMVDLFRLPILKMLLNFSGRHLGARLYQKR-LGVCHGDDLFYLFPFSLMGFPQSVKTASDLRTS--KHFLSLLTNFAHFGNPTPQNKMGFLWEPWTKTSNAQLRIGSGLVMEI--------DPLVEKRIQFWNQL 654
            G +RG  + S  +N +P  S+  LPY +PPLGE RF  P P    W G  DG  +  P C+Q  +        +G EDCL LN+  P       R   PV+++ HGG++ + S     + P Y++D+ V+ + +NYR+G +GFL+LETD+APGNLGLRDQ LA+ W ++ +    G+++ +TL+G  +GA S  +HLVSP + +G F ++I  SG     + L   ++   Y K  A ++G        +IL+CL+  P   +  K   F   + V  P PW P++D +FA  P LP   E+++++   +++IP+L+G  +EEG L++  FF   +     LF Q+    P LLFN E + VT   Q  V  +K+ F P       S S  K++  +F+  +F   + + + LL +HG  I+ Y+++Y G+ S  DL      K+ L  S +  G  L+ +   G CHGD+LF +F    +  P S    SD   S  +  +++  NFA  GNPTP   MG+  +  +K  + Q    +G+V EI        D  +EKR+ F++++
Sbjct:   42 GDVRGIIQYSPLQN-KPYASYFGLPYALPPLGERRFARPEPYSNAWEGIRDGT-QSPPICVQQDIHRNNPNDTIGVEDCLVLNINQPLTCTRENRC--PVIIWLHGGSYALLSGSPYTFNPLYFMDHNVIFIGINYRLGAMGFLTLETDEAPGNLGLRDQSLAIKWIRDEIDNLYGNKDQITLMGHGSGAHSALIHLVSPFNKKGTFTRIITQSGSPFEDTNLRFAKSRKEYAKKLAASVG-----CTKEILKCLRSRPADILQTKVQTFNIINQVFTPNPWVPVIDIKFAHDPVLPDYPENIVKNTNFSRSIPILTGSVAEEGMLLMKRFFQHPE-----LFAQFTRTLPFLLFNLEDESVTPKVQDLVEIVKKFFIPKGQL---SYSQNKQIIAMFTDMVFYGKIGRAIQLLRDHG-PIYQYIYKYFGTHSFGDLSFYSDFKLGLKLSLQSRGIGLFMRNGFGTCHGDELFDIFKIGFLKAPMSSGPISDFDKSVGQSLITMWINFARTGNPTP---MGYFLDDNSKWLSIQE--SNGMVAEIKTKTRMIEDTFLEKRVNFYHRV 585          

Query:  100 VVLTRLGKIRGRRSQTRNGRPIFSFRALPYGVPPLGELRFRPPLPVEPWAGSLDGAGRESPQCIQVSVLSPESKMYLGSEDCLYLNVFTPHLPGAGKRSLFPVMVFFHGGAFNVGSNDSRLYGPEYWLDYGVVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCASTSFLHNDRAPSVYGKAFARALGIDV-AQSESDILECLQKVPIKSIMDKSTVFKDWDVTN----PL-PWKPIVDGQFATQPFLPQPFEDLIRSGFANKAIPVLSGYTSEEGLILSAFFHKSQRRWDLLFNQWEIWAPQLLFNRESDLVTKADQSCVSQIKEKFFPGEGFPARSESNLKRLEQLFSLAIFQAPLRKDLDLLS-EHGFSIFAYVFQYEG--SMSMVDLFRLPILKMLLNFSGRHLGARLYQKRL--GVCHGDDLFYLFPFSLMGFPQSVKTASDLRTSKHFLSLLTNFAHFGNPTPQNKMG---FLWEPWTKTSNAQLRIGSGLVMEIDPLVEKRIQFWNQLTTI-NRFQTSHKP 666
            V +T+ G + G   +TR G  I +FR + +  PP+G+LRF+ P+P   W G +  A +    C Q     P+  +++G EDCL+LNVF+  L    KR   PV+V+ HGG F  G   +  Y P+Y LD  +VLVT+ YR+G  GFLS E   APGN G+ DQV AL W + ++  F GD N++T++G+ AG  S   H++S +SRG FH+ I+LSG A  S+  + + P    K  AR L     A    +++EC++ + ++ +M+    F +W   N    P+  W P VD + A   F+P    DL+ +G   + +P ++G T +EG    + F    R        +E   P L+F    D  ++A +    ++ + ++ G+     ++ N K L    S + +  P+     + S +    ++ Y F Y+G  S++ +D    P               ++ Q+ +  GV +GDDL YLFP     F        DL  S+ F+ L T+FA  G P  +   G   F+W P    +   L IG+ + M++     +R+ FW  +    N  + ++KP
Sbjct:   88 VAITKSGMLWGTIEETRTGGRILAFRGIRHVRPPVGDLRFKAPVPFPRWDG-IREAKKNGHFCPQHMYYKPD--VWIGEEDCLWLNVFSRDLAVNKKR---PVIVWIHGGNFVRGX--AADYEPDYLLDEDIVLVTIQYRLGMFGFLSSEDQYAPGNYGMLDQVAALQWVKTNIDAFSGDVNHITIMGQQAGGASVHYHMLSSLSRGLFHRAISLSGSA-LSWWASLKRPLERAKKLARLLECPYDADKSKEMIECIRGIEMEKMMNTHPNFYEWKHLNQNQEPVNAWSPRVDPEAALS-FMPNEPIDLMTAG-NFQHVPWIAGITDDEGAFKGSAFFSEMRNVREFEEDFEKIGP-LMFGFH-DGQSEAPKMMARKVMDYYWNGKEL---TKENAKSLVDALSXSSYAHPVDXASKIQSIKSQAPVYVYHFGYKGVNSLTQMDTNSHP--------------PQVIQRDIPYGVGNGDDLIYLFPILSGAF--RPLPHDDLIFSQRFIQLFTSFATDGKPVIKMGEGIDDFVWHPVDPNNATHLDIGNEMRMDLGLPNHERMNFWQSMPVYWNSDRENYKP 637          

Query:  100 VVLTRLGKIRGRRSQTRNGRPIFSFRALPYGVPPLGELRFRPPLPVEPWAGSLDGAGRESPQCIQVSVLSPESKMYLGSEDCLYLNVFTPHLPGAGKRSLFPVMVFFHGGAFNVGSNDSRLYGPEYWLDYGVVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCA-STSFLHNDRAPSVYGKAFARALGIDVAQSESDILECLQKVPIKSIMDKSTVFKDWDVTNPLPWKPIVDGQFATQPFLPQPFEDLIRSGFANKAIPVLSGYTSEEGLILSAFFHK------SQRRWDLLFNQWEIWAPQLL-----FNRESDLVTKADQSCVSQIKEKFFPGEGFPARSESNLKRLEQLFSLAIFQAPLRKDLDLLSEHGFSIFAYVFQYEGSMSMVDLFRLPILKMLLNFSGRHLGARLYQKRLGVCHGDDLFYLFPFSLMGFPQSVKTASDLRTSKH-FLSLLTNFAHFGNPT--PQNKMGFLWEPWTKTSNAQLRIGSGLVMEIDPLVEKRIQFWNQ 653
            +V T  G I G R  + +    +SF+ + Y +PP+ +LRF+ P  +EPW  +++ A  +   C Q  +    + + LG EDCL+LNV+TP +  + KR+   VMV  HGGAF +G   S L+GP+Y ++  +VLV  NYR+G LGFL+ +      N G++DQ++AL W +E++  FGGD N VT++GE AGA S  +  +SP ++G F  VIALSG A    F+ N+  P    K  A  L       + DI+EC+ +   + I++KS     +  T P  + P VDG       LP   E+L+ +G  +K +P++ G T   G    AF+++      +   +D  F   ++  P+LL     +N +   +T++       I++++F         E   + +E L  + +F     +    ++ H    + Y+F Y G  S+V            NF G        Q  +GV HGD++ Y+F  ++ G   S+  A DL+ +K+ F  LL++FA    PT    + +   W P     N  L+I + L M  D   +  ++FWN+
Sbjct:   22 IVKTSKGPIMGLREDSSSNGYFYSFKGIRYAMPPVEDLRFKAPTELEPWTETVE-AVEDGHICPQYDI---ANSIPLGDEDCLFLNVYTPKI-DSKKRA---VMVHIHGGAFILGGGVSHLFGPDYLMENDIVLVNFNYRLGALGFLTTKDTMETANNGIKDQIMALKWVKENIDKFGGDPNKVTIIGEDAGAASATILSMSPAAQGLFQGVIALSGNALCDQFIQNN--PDEAAKELAARLECSSTDGK-DIIECISRKTQQDIVEKSNSMMMF-YTFPRWFAPNVDGD-----ILPDRPENLLSNGQFSK-VPIVLGQTKNGG----AFYYRLTINSFNNGGYDDNFIDHKL--PRLLPVMTNYNSKLYPITRS-------IRKRYFVNVDMENEDEFRPRYIEFLTDM-LFTKCTDEFARAIANHSVPTYEYLFDYRGQYSIV------------NFQGE-------QVDMGVVHGDEMQYVF-HNIWGEDFSMSPA-DLKFTKNIFTPLLSSFAKTSVPTLPTIDDINVSWSPRAPNKNRILKISNKLEMNED-YKKDILKFWNE 536          

Query:  100 VVLTRLGKIRGRRSQTRNGRPIFSFRALPYGVPPLGELRFRPPLPV-EPWAGSLDGAGRESPQCIQVSVLSPESKMY--LGSEDCLYLNVFTPHLPG--------AGKRSLFPVMVFFHGGAFNVGSNDSRLYGPEYWLDYGVVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCASTSFLHNDRAPSVYGKAFARALGIDVAQSESDILECLQKVPIKSIMDKSTVFKDWDVTN-----PLPWKPIVDGQFATQPFLPQPFEDLIRSGFANKAIPVLSGYTSEEGLILSAFFHKSQRRWDLLFNQWEIWAPQLLFNRESDLVTKADQSCVSQIKEKFFPGEGFPARSESNLKRLEQLFSLAIFQAPLRKDLDLLSEHGFSIFAYVFQYEGSMSMVDLFRLPILKMLLNFSGRHLGARLYQKRLGVCHGDDLFYLFPFSLMGFPQS-VKTASDLRTSKHFLSLLTNFAHFGNPTPQNKMGFLWEP 621
            +V +  G ++G R +        +F  +PY +PP GE RFR P P   PW  +L       P C Q      +S ++   G+EDCLYLN+F+P              + +LFPVMV+ HGG F  G+     Y   Y++   ++LV ++YR+GPLGFL+L  + A GN G+ DQ+LAL W Q+++  FGGD   VT+ GES+GA+S   H+  PMS+  F   I  SG      +       ++    A    I V     D  EC+QK+P+  I++K+    D ++       P PW P+++G +          +++      + A  V+ G TS EG + ++ F       +   ++WE             L T  D+S   +    ++ G        S ++    L S   +  P  + +  ++  G  ++ Y++ ++G +SM D            F  R+   +   K  G  H D+L    PF    +P++ +K   D +  +  + + TNFA  G+P    K G+ W+P
Sbjct:   36 IVHSPSGLVQGAREKGHQ-----AFYGIPYALPPTGERRFRSPEPYPTPWKRTLQAGRSYPPACPQQLRSYFKSLLWDVEGNEDCLYLNIFSPDSASLQLSNESPPSQENLFPVMVWIHGGNFMSGTASD--YESIYFMTKDIILVMISYRLGPLGFLNLGEEYARGNQGIEDQILALSWIQDNISSFGGDPQRVTIFGESSGAISVLHHMSVPMSKLLFQSAIIQSGSIYQPTIKETFMMEMHEAWIAEMGCIGVI----DTQECIQKLPLAKIVNKNPFLSDCNLKKNGHPFPNPWFPVLEGSYL--------LKEVSAENKKSHAPRVMIGTTSNEGFLATSRFMLQNNYTEGFMSKWE---------ECFKLNTAGDESYDLEPVMDYYFGSNKKPDFPSQVQNFSNLISDFWYNGPTFETVKEIANKGSPVYYYLYDHDGFLSMTDSLSRASYD-YWKFIVRYAFGQESGKTNGASHADEL----PFLFREYPRNLLKRPVDEKMWRLMIDVWTNFATSGDPNGA-KEGYNWKP 540          

Query:  148 WAGSLDGAGRESPQCIQVSVLSPESKMYLGSEDCLYLNVFTPHLPGAGKRSLFPVMVFFHGGAFNVGSNDSRLYGPEYWLDYG-VVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCASTSFLHNDRAPSVYGKAFARALGIDVAQSESDILECLQKVPIKSIMDKSTVFKDWDVTNPLPWKPIVDGQFATQPFLPQPFEDLIRSGFANKAIPVLSGYTSEEGLILSAFFHKSQRRWDLLFNQWEIWAPQLLFNR-ESDLVTKADQSCVSQIKEKFFPGEGFPARSESNLKRLEQLFSLAIFQAPLRKDLDLLSEHGFS---IFAYVFQYEGS-MSMVDLFRLPILKMLLNFSGRHLGARLYQ-KRLGVCHGDDLFYLFPFS-LMGFPQSVKTASDLRTSKHFLSLLTNFAHFGNPT 610
            W G+ D A    P+ +Q           +G EDCLYLNV+TP LP    +  FPV+V+ +GG +  G    R Y P+Y ++ G VV+VT+NYR+GPLGFL+L  +  PGN+GL DQ LA+ W + H+G FGGD + +TL+G  AG++    H+VS  S G FHK I +SG    +F+    +  V   A   ++  + A+      EC          DKS                          F  +   + I++G  NK +P+L G +   G+ L +    S+   D L   W +   +L+ NR E+ L  + D   V+ +K+ +F  E F    +    +L      A+F      D  + + HG S   I+ Y F +  S +S  D+F L  ++++L      +G +++  KR G+ H D+LF +F  +    F  S+    D + +  F S + NFA  GNPT
Sbjct:    5 WEGTRD-ASSPCPKPVQFIPNYGGISSVIGEEDCLYLNVYTPDLPVTENQKKFPVIVWIYGGNYLWGDASERFYFPKYLIESGSVVIVTLNYRLGPLGFLTLGNETVPGNMGLWDQRLAMEWIRTHIGNFGGDADEITLMGHDAGSVCITNHMVSKSSAGLFHKAICMSG----TFVSEKFSFDVSDPASLNSIKEEFAK------EC----------DKS--------------------------FFSESQLETIKTGEFNK-MPILMGTSRHSGIALISEAIGSEDNKDRLRRDWTVLGGELILNRPENILRPQEDLQFVNTLKKFYFDQEEF--TEDGGFDQLINAVGDAVFLGA--NDYFIKAVHGGSAQPIYLYNFDHMYSNISGGDVFSLSTIQLILKLFLSKIGIKMFNDKRPGISHWDELFCIFSGNDSFLFKHSISNQVDQKVANIFTSFIINFASSGNPT 423          

Query:  100 VVLTRLGKIRGRRSQTRNGRPIFSFRALPYGVPPLGELRFRPPLPVEPWAGSLDGAGRESPQCIQV-SVLSPE---SKMY----LGSEDCLYLNVFTPHLPGAGKRSLFPVMVFFHGGAFNVGSNDSRLYGPEYWL-DYGVVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCASTSF-LHNDRAPSVYGKAFARALGIDVAQSESD-ILECLQKVPIKSIMDKSTVFKDWDVTNPLPWKPIVDGQFATQPFLPQPFEDLIRSGFANKAIPVLSGYTSEEGLILSAFFHKSQRRWDLLFNQWEIWAPQLLFNRE----SDLVTKADQSCVS-QIKEKFFPGEGFPARSESNLKRLEQLFSLAIFQAPLRKDLDLLSEHGFSIFAYVFQYEGSMSMVDLFRLPILKMLLNFSGRHLGARLYQKRLGVCHGDDLFYLFPFSLMGFPQSVKTASDLRTSKHFLSLLTNFAHFGNPTPQNKMGFLWEPW---TKTSNAQLRIGSGLVMEIDPLVEKRIQFWNQ 653
            V+ T+ GKIRG   ++   R + ++  +PY  PP+G LRFR P  ++ W G +    R    CIQV   L P    ++M+      SEDCLYL+V  P     G      V+V+ +GG F  G++   +Y P   + +  ++ V + YR+  LGFL  +T+D PGN GL DQ++AL W + ++  FGGD + +T+ GE AG  S  LHL+SP+SR  F + I  S  A   + +   +   + G+  A  +     +  +  ++ECL++     ++++  +     +    P+ PIVDG F  +     P + L    +  K   +L G   EEG     ++       DL  N   ++  +  F R     +  V K  +  ++ +  +   P +  P ++   + R+   +    F  P      + +  G +++ Y F    S S                         +    GV HGD++ ++F  +L       K  S++  SK  +    NFA  GNP+      +    W   T T    L + +     ++ L  K+  FW +
Sbjct:   37 VITTKKGKIRGVTLKSATNREVDAWYGIPYAQPPVGNLRFRHPRHIDAWEG-IKETTRPPNSCIQVVDTLFPGFEGAEMWNVNTEPSEDCLYLSVHVPKPRPTGS----AVLVWIYGGGFYSGTSTLEVYDPRVLVSEENIIFVAMQYRVASLGFLFFDTEDVPGNAGLYDQMMALQWVKNNIEEFGGDPDKITIFGEXAGGCSVALHLLSPLSRNLFSQAIMQSASALVPWGVITKKESIIRGRRLAEMMSCPYDEKNTKAMIECLRQKDATEMVNQEWIGIISGIAE-FPFVPIVDGSFLDE----SPGKSLTTKNY--KKTNILIGANKEEGNYFIMYYLT-----DLFKNTESVYVDRTDFIRSVSELNHYVKKMGREAITFEYTDWLNPND--PIKNREAIDRMVGDYQ---FICPTADFARIYASTGNNVYMYYFTERSSTSP------------------------WPTWSGVLHGDEIAFVFGEALNKSKNYDK--SEIALSKRMMGYWANFAKTGNPSLSADGTWSTNYWPLHTPTKQEVLELNANYSRVLEGLRVKKCAFWKK 561          

Query:  100 VVLTRLGKIRGRRSQTRNGRPIFSFRALPYGVPPLGELRFRPPLPVEPWAGSLDGAGRESPQCIQV-SVLSPE---SKMYLG----SEDCLYLNVFTPHLPGAGKRSLFPVMVFFHGGAFNVGSNDSRLYGPEYWL-DYGVVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCA---------------STSFLHNDRAPSVY--------------GKAFARALGIDVAQSESD-ILECLQKVPIKSIMDKS---TVFKDWDVTNPLPWKPIVDGQFATQPFLPQPFEDLIRSGFANKAIPVLSGYTSEEGLILSAFFHKSQRRWDLLFNQWEIWAPQLLFNRE-SDLVTKADQSCVSQIKEKFFPGEGFPARSESNLKRLEQLFSLAIFQAPLRKDLDLLSEHGFSIFAYVFQYEGSMSMVDLFRLPILKMLLNFSGRHLGARLYQKRLGVCHGDDLFYLFPFSLMGFPQSVKTA---SDLRTSKHFLSLLTNFAHFGNPT---PQNKMGFLWEPWTKTSNAQLRIGSGLVMEIDPLVEKRIQFW 651
            V+ TR GKIRG   ++   + + ++  +PY  PP+G LRFR P  +  W G +    +    CIQV     P    S+M+      SEDCLYL+V  P  P   K +   V+V+ +GG F  G++   LY P   + +  ++ V + YR+  LGFL  +T+D PGN GL DQ++AL W + ++  FGGD + +T+ GE AG  S  LHL+SP+SR  F   I  S  A                       R P                 G+  A  +     ++ ++ ++ECL +     ++++    TVF      +  P+ PIVDG+F  +     P + L    +  K   +L G   +EG     ++       +L      ++  +  F R  SDL    + +    I  ++      P     N + ++++     F  P      + +  G +I+ Y F    S S                         +    GV HGD++ ++F     G P +       S++  SK  +S   NFA  GNP      N    +W   T      L + +      + L  ++  FW
Sbjct:   37 VITTRKGKIRGVTLKSATNKEVDAWYGIPYAQPPVGNLRFRHPKDINAWDG-MKETTKHPNSCIQVVDTFFPGFEGSEMWNTNTEQSEDCLYLSVHAPK-PRPTKSA---VLVWIYGGGFYSGTSTLELYDPRVLVSEENIIFVGIQYRVASLGFLFFDTEDVPGNAGLYDQMMALQWVKNNIEAFGGDPDKITIFGEXAGGCSVALHLLSPLSRXLFSXAIMQSSSALVPWGVISKKESIRRGRRLAEEMRCPYALVPWGVISKKESIRRGRRLAEEMRCPYGENNTNAMIECLLQKDATELVNQEGSGTVFG----ISEFPFVPIVDGKFMDK----TPEKSLKEKDY--KKTNILMGVNKDEGNFFIMYYLP-----ELFKKNENVYINRTDFIRSVSDLNIYVNNAGREAITFEYTDWLN-PNDPIKNREAIDRMVGDYQFTCPTADFARIYASTGNNIYMYYFTERSSTSP------------------------WPTWSGVLHGDEIAFVF-----GEPLNTSKNYDDSEIALSKRIMSYWANFAKTGNPNVLANGNYSNKIWPLHTPIKQEVLELNANYSRVFEGLRVRKCAFW 587          

Query:  279 DRNNVTLLGESAGAMSNF-LHLVSPMSRGFFHKVIALSG-CASTSFLHNDRAPSVYGKAFARALGIDVAQSESDILECLQKVPIKSIMDKSTVFKDWDVTNPLPWKPIVDGQFATQPFLPQPFEDLIRSG-FANKAIPVLSGYTSEEGLILS-AFFHKSQRRWDLLFNQWEIWAPQLLFNRESDLVTKADQSCVSQIKEKFFPGEGFPARSESNLKRLEQLFSLAIFQAPLRKDLDLL--SEHGFSIFAYVFQYEGSMSMVDLFRLPILKMLLNFSGRHLGARLYQKRLGVCHGDDLFYLFPFSLMGFPQSVKTASDLRTSKHFLSLLTNFAHFGNPTPQNKMGFLWEPWTKTSNAQLRIGSGLVMEIDP---LVEKRIQFWNQ 653
            D N++T+ G SAG +S   L + +    G FHK I+ S       F+H    PS Y   F+  +G D +++  DI +CL++  +  +++K  +F+ + +  P PWKP+VD ++A++P     F DLI+ G F N  +P+L G TSEEG + S  FF   + ++  L   ++I    LL   +   VT  D + V+ I  ++   +     SE N+ +L ++ +   F  P+ K + L   S HG  IF Y ++Y+GS S              +  G  LGA          HGD+LF LF    +      K  SDL      +   T+FA  G+P  +         WT  SNA   +    V+  +P   +V KR  ++N+
Sbjct:   30 DENSITIFGSSAGGISVLTLMMAAHKVPGLFHKXISQSTPMIDAPFMHLTHNPSYYSLLFSNEMGCD-SENSIDISKCLKEKDVYELINKQDMFEKF-MNFPYPWKPVVDFEYASKPLFSMGFVDLIKHGLFTN--VPLLMGGTSEEGAMFSPEFFKNDEEKFQELNENFDITGATLLMGIDEADVTDEDSATVNIINIEYLDSDNITYSSE-NILKLVKMLTDVHFLGPIDKQVQLFANSSHG-PIFYYNYRYKGSHST-------------SIKGLDLGA---------SHGDELFLLFKIQDISLSTEDKKMSDL-----LIDYWTSFAIHGSPNSK---------WTPVSNA---VAPKYVILNNPSSTIVAKRESYFNE 368          

Query:  155 AGRESPQCIQVSVLSPESKMYLGS--------EDCLYLNVFTPHLPGAGKRSLFPVMVFFHGGAFNVGS-NDSRLYGPEYWLDYGVVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGC--ASTSFLHNDRAPSVYGKAFARALGIDVAQSESDILECLQKVPIKSIMDKSTV-FKDWDVTNPLPWKPIVDG-----------QFATQPF--LPQPFEDLIRSGFANKAIPVLSGYTSEEGL-------ILSAFFHKSQRRWDLL----FNQWE-IWAPQLLFNRESDLVT-KADQSCVSQIKEKFFPGEGFPARSESNLKRLEQLFSLAIFQAPLRKDLDLLSEHGFSIFAYVFQYEGSMSMVDLFRLPILKMLLNFSGRHLGARL-YQKRLGVCHGDDLFYLFPFSLMGFPQSVKTASDLRTSKHFLSLLTNFAHFGNPTPQNKMGFLWEP 621
             G +S   +  + + P+   Y+G+        E+CL+LNVFTP +  +G+  LFPVM + HGG F  GS N+   +   YW    VV+VT+NYR+G LGFLS     APGN GL DQ +AL W  +++  F GDR  +T+ G  AG  S  +  V P ++    +VI++SG   A  + + +          F   +G  +  S   +++CL+K   +   D + + FK    T   PW PI+             ++ +  F  LP+  E L  +   N ++  ++G   ++          L+  +    + +D++      Q+     P+ +FN    + T   D   VS I+E+F                    +S   F+AP    +  L ++    + YV       + V+  +LP          R +   L Y    G    D +F+     +  F   + T SD   S+ F+   +NF+ +G+PTP+  +G  WEP
Sbjct:  204 GGWQSYNAVDWAPVCPQPIRYVGATKNSPLMDENCLFLNVFTPTV-ESGQSQLFPVMFYIHGGEFQHGSGNEFSGHQLSYWG--RVVVVTINYRLGALGFLSTGDQHAPGNYGLLDQAMALKWVYDNIYAFQGDREKITVFGPGAGGASAGILAVMPKTKNMVRRVISMSGSPFADWATIRDKFRAMNTSLVFGERVGCTI-DSSWKLVDCLRKG--RKFHDLANIEFKPEIGT--WPWAPIIQKNISVPEEGWYQEWTSDDFMALPELVEVLYENQEYNPSLEYMTGVARDDAAYMIYNNKTLAPDYKVDWKFFDMMVKDHIKQYNYTLNPEGIFNAIKYMYTYYPDPDNVSHIREEFI-----------------NFYSDFFFRAPQDAMVKTLVQNRVDTYMYV-----QNTTVEALKLPYW--------REISHNLEYYFLTGAPFMDSVFFPEDKQVTRF---LWTESDRNMSEFFIYAFSNFSWYGHPTPKTILGVHWEP 668          

Query:  101 VLTRLGKIRGRRSQTRNGRPIFSFRALPYGVPPLGELRFRPPLPVEPWAGSLDGAGRESPQCIQVSVLSPESKMYLGSEDCLYLNVFTPHLPGAGKR-SLFPVMVFFHGGAFNVGSNDSRLYGPEYWLDYG-VVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCASTSFLHNDRAPSVYGKA--FARALGIDVAQSESDILECLQKVPIKSIMDKSTVFKDWDVTNPLPWKPIVDGQFATQPFLPQPFEDLIRSGFANKAIPVLSGYTSEEGLILSAFFHKSQRRWDLLFNQWEIWAPQLLFNRESDLVTKADQSCVSQIKEKFFPGEGFPARSESNLKRL--EQLFSLAIFQAPLRKDLDLLSEHGFSIFAYVFQYEGSMSMVDLFRLPILKMLLNFSGRHLGARLYQKRLGVCHGDDLFYLFPFSLMGFPQSVKTASDLRTSKHFLSLLTNFAHFGNPTPQNKMGFLWEPWTKT 625
            V    G+I G    T NGR I+SF  +PY  PP+   RF+ P PV+PW G  + A      C+ +   S  SK+ +G EDCL+LNV+TP LP       L  V+V  HGG +  G  +  LYGP Y LD    V V++NYR+G LGF S      PGN GL+DQV AL W Q+++  FGGD N+VT+ G SAGA S   HL+SPMS+G F++ I  SG A   F H   A +V  K    A  LG     S  +I+ECL+  P K+I      F  W      P+ P V+     + FLP   E L+        IPVL     +EGLI S F    +  ++ L N W    P +L    +             IKE +F  +     ++SNL ++  ++ F     +A       + +++   ++ Y F Y G+ S V  F                  + Y +     HGD+  Y+    + GF        D +  K  +++   F   G P  +N    +W P +K 
Sbjct:   29 VQVHSGEIAGGFEYTYNGRKIYSFLGIPYASPPVQNNRFKEPQPVQPWLGVWN-ATVPGSACLGIEFGS-GSKI-IGQEDCLFLNVYTPKLPQENSAGDLMNVIVHIHGGGYYFG--EGILYGPHYLLDNNDFVYVSINYRLGVLGFASTGDGVLPGNNGLKDQVAALKWIQQNIVAFGGDPNSVTITGMSAGASSVHNHLISPMSKGLFNRAIIQSGSA---FCHWSTAENVAQKTKYIANLLGCPTNNS-VEIVECLRSRPAKAIAKSYLNFMPWRNFPFTPFGPTVEVA-GYEKFLPDIPEKLVP-----HDIPVLISIAQDEGLIFSTFL-GLENGFNELNNNWNEHLPHILDYNYTISNENLRFKTAQDIKEFYFGDKPISKETKSNLSKMISDRSFGYGTSKAAQH----IAAKNTAPVYFYEFGYSGNYSYVAFFD----------------PKSYSRGSSPTHGDETNYV--LKVDGF-TVYDNEEDRKMIKTMVNIWATFIKSGVPDTENSE--IWLPVSKN 518          

Query:  101 VLTRLGKIRGRRSQTRNGRPIFSFRALPYGVPPLGELRFRPPLPVEPWAGSLDGAGRESPQCIQVSVLSPESKMYLGSEDCLYLNVFTPHLPGAGKR-SLFPVMVFFHGGAFNVGSNDSRLYGPEYWLDYG-VVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCASTSFLHNDRAPSVYGKA--FARALGIDVAQSESDILECLQKVPIKSIMDKSTVFKDWDVTNPLPWKPIVDGQFATQPFLPQPFEDLIRSGFANKAIPVLSGYTSEEGLILSAFFHKSQRRWDLLFNQWEIWAPQLLFNRESDLVTKADQSCVSQIKEKFFPGEGFPARSESNLKRL--EQLFSLAIFQAPLRKDLDLLSEHGFSIFAYVFQYEGSMSMVDLFRLPILKMLLNFSGRHLGARLYQKRLGVCHGDDLFYLFPFSLMGFPQSVKTASDLRTSKHFLSLLTNFAHFGNPTPQNKMGFLWEPWTKT 625
            V    G+I G    T NGR I+SF  +PY  PP+   RF+ P PV+PW G  + A      C+ +   S  SK+ +G EDCL+LNV+TP LP       L  V+V  HGG +  G  +  LYGP Y LD    V V++NYR+G LGF S       GN GL+DQV AL W Q+++  FGGD N+VT+ G SAGA S   HL+SPMS+G F++ I  SG A   F H   A +V  K    A  +G     S  +I+ECL+  P K+I      F  W      P+ P V+     + FLP   E L+        IPVL     +EGLI S F    +  ++ L N W    P +L    +             IKE +F  +     ++SNL ++  ++ F     +A       + +++   ++ Y F Y G+ S V  F                  + Y +     HGD+  Y+    + GF        D +  K  +++   F   G P  +N    +W P +K 
Sbjct:   29 VQVHSGEIAGGFEYTYNGRKIYSFLGIPYASPPVQNNRFKEPQPVQPWLGVWN-ATVPGSACLGIEFGS-GSKI-IGQEDCLFLNVYTPKLPQENSAGDLMNVIVHIHGGGYYFG--EGILYGPHYLLDNNDFVYVSINYRLGVLGFASTGDGVLTGNNGLKDQVAALKWIQQNIVAFGGDPNSVTITGMSAGASSVHNHLISPMSKGLFNRAIIQSGSA---FCHWSTAENVAQKTKYIANLMGCPTNNS-VEIVECLRSRPAKAIAKSYLNFMPWRNFPFTPFGPTVEVA-GYEKFLPDIPEKLVP-----HDIPVLISIAQDEGLIFSTFL-GLENGFNELNNNWNEHLPHILDYNYTISNENLRFKTAQDIKEFYFGDKPISKETKSNLSKMISDRSFGYGTSKAAQH----IAAKNTAPVYFYEFGYSGNYSYVAFFD----------------PKSYSRGSSPTHGDETSYV--LKMDGF-YVYDNEEDRKMIKTMVNIWATFIKSGVPDTENSE--IWLPVSKN 518          

Query:  101 VLTRLGKIRGRRSQTRNGRPIFSFRALPYGVPPLGELRFRPPLPVEPWAGSLDGAGRESPQCIQ-VSVLSPESKMYLGSEDCLYLNVFTPHLPGAGKRSLFPVMVFFHGGAFNVGSNDSRLYGPEYWLDYGVVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCASTSFLHNDRAPSVYGKAFARALGIDV---AQSESDILECLQKVPIKSIMDKSTVFKDWDVTNPL-PWKPIVDGQFATQPFLPQPFEDLIRSGFANKAIPVLSGYTSEEGLILSAFFHKSQRRWDLLFNQWEIWAPQLLFNRESDLVTKADQSCVSQIKEKFFPGEGFPARSESNLKRLEQLFSLAIFQAPLRKDLDLLSEHGFS-IFAYVFQYEGSMSMVDLFRLPILKMLLNFSGRHLGARLYQKRLGVCHGDDLFYLFPFSLMGFPQSVKTASDLRTSKHFLSLLTNFAHFGNP 609
            V T  G IRG   ++R+ R   ++  +PY   P+G+ RF+PP P++ W+  L  A ++S  C+Q +   +       GSEDCLY+N++ P      ++ L PVM + HGGAF   S +        ++D  +V V +NYR+GP GFLS      PGN+GL+DQ +AL W   ++  FGG+ N +T+ G SAG  S   H +SPMS G F + I++SG A   +     AP       A+ LG  +     +   +++CLQ  P + I      F  W + NP  P+ P+V+  + + PF+     ++I +G     +P +SG  S+EGL  +A F  + +    L + W+  AP LL   + +     DQ      K K +     P   +  ++ + Q+ S  +F     K + L +    S ++ Y + Y    S+ ++            SG            GVCHGDD+F     +L     +V    DL   +  ++  T+FA  G P
Sbjct:   28 VSTFTGNIRGYYKKSRSDRLYEAYEGIPYAQSPVGKFRFQPPRPIKKWSKDL-SATKKSSVCMQYLMTFTTHGNRVKGSEDCLYINIYVP--VRNNRKPLLPVMFWIHGGAFQFASGNEA--NETLFMDRNIVFVAINYRLGPFGFLSTGDIVVPGNMGLKDQSMALRWVFNNIKSFGGNPNKITIFGMSAGGASVHYHYLSPMSAGLFKRGISISGVAFCPWAQTKHAPEK-----AKKLGALMKCRTDNTKKMIDCLQSRPARIIAQAVGDFMFW-LYNPFTPFGPVVE-TYGSNPFISNSPINIINNGQVYD-VPWISGVVSKEGLYTAAEFVDNAKLLWHLNDHWDEIAPYLL---DFNYTIPLDQHRQVAKKIKNYYLRSGPINYDK-VESIIQMMSDRLFNIDFEKAVRLQARINKSPVWTYYYSYRAEHSVSEI-----------LSGGS------TTDYGVCHGDDIF----LTLNSIISNVTKPQDLAMQQLLINFYTSFAIQGIP 504          

Query:  100 VVLTRLGKIRGRRSQTRNGRPIFSFRALPYGVPPLGELRFRPPLPVEPWAGSLDGAGRESPQCIQVSVLSPESKMYLGSEDCLYLNVFTPHLPGAGKRSLFPVMVFFHGGAFNVGSNDSRLYGPEYWLDYGVVLVTVNYRIGPLGFLSL--ETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCASTSF-LHNDRAPSVYGKAFARALGIDVAQSESDILECLQKV-PIKSIMDKSTVFKDWDVTNPL--PWKPIVDGQFATQPFLPQ-PFEDLIRSGFANKAIPVLSGYTSEEGLILSAFFHKSQRRWDLLFNQWEIWAPQL-LFNRESDLVTKADQSC--VSQIKEKFFPGEGFPARSESNLKRLEQLFSLAIFQAPLRKDLDLLSEHGFSIFAYVFQYEGSMSMVDLFRLPILKMLLNFSGRHLGARLYQKRLGVCHGDDLFYLFPFSLMGFPQSV--KTASDLRTSKHFLSLLTNFAHFGNPTP--QNKMGFLWEP--WTKTSNAQLRIGSGLVMEIDPLVEKRIQFWNQL 654
             V T+ G +RG+R+ +  G+   SF+ +PY   P GELRF+ P+P + W  +LD     + QC          +  +G ED L +NVF   +      +  PVM++ +GG F  G++ + LYGP++ +   +VLV+ NYRIG LGFL    E D  PGN GL+DQ LA+ W  E++  FGGD   VTL G SAGA S   HL+S  S+  F + I +SG   +S+ L   R    + +  A+A+G D    ES  L  L++  P   +  +  +  D D+ + +  P+ P V+     Q  +P+ PFE + R+ + +K I ++ G TSEEGL+L     K +   +LL +      P L L N   +L    ++     +++K++++P +  P+  E+NL  +  + S  +F   L + + L          +V++        + +R+    M+++            K  G  H D+L YLF      F Q V  K   + R  +  + + + F   G+P      K G ++EP   TK +   L I +  V  +D     R+  W+ +
Sbjct:    7 TVQTKYGPVRGKRNVSLLGQEYVSFQGIPYARAPEGELRFKAPVPPQKWTETLDC----TQQCEPCYHFDRRLQKIVGCEDSLKINVFAKEI---NPSTPLPVMLYIYGGGFTEGTSGTELYGPDFLVQKDIVLVSFNYRIGALGFLCCQSEQDGVPGNAGLKDQNLAIRWVLENIAAFGGDPKRVTLAGHSAGAASVQYHLISDASKDLFQRRIVMSGSTYSSWSLTRQRN---WVEKLAKAIGWDGQGGESGALRFLRRAKPEDIVAHQEKLLTDQDMQDDIFTPFGPTVEPYLTEQCIIPKAPFE-MARTAWGDK-IDIMIGGTSEEGLLL---LQKIKLHPELLSH------PHLFLGNVPPNLKISMEKRIEFAAKLKQRYYP-DSIPSM-ENNLGYV-HMMSDRVFWHGLHRTI-LARAARSRARTFVYRICLDSEFYNHYRI----MMID-----------PKLRGTAHADELSYLFS----NFTQQVPGKETFEYRGLQTLVDVFSAFVINGDPNCGMTAKGGVVFEPNAQTKPTFKCLNIANDGVAFVDYPDADRLDMWDAM 533          

Query:  106 GKIRGRRSQTRNGRPIFSFRALPYGVPPLGELRFRPPLPV-EPWAGSLDGAGRESPQCIQVSVLSPESKMYLGSEDCLYLNVFTPHLPGAGKRSLFPVMVFFHGGAFNVGSNDSRLYGPEYWLDYG-VVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCASTSFLHNDRAPSVYGKAF--ARALGIDVAQSESDILECLQKVPIKSIMDKSTVFKDWDVTNPLPWKPIVDGQFATQPFLPQPFEDLIRSGFANKAIPVLSGYTSEEGLILSAFFHKSQRRW---DLLFNQWEIWAPQLLFNRESDLVTKADQSCVS-QIKEKFFPGEGFPARSESNLKRLEQLFSLAIFQAPLRKDLDLLSEHGFS-IFAYVFQYEGSMSMVDLFRLPILKMLLNFSGRHLGARLYQKRLGVCHGDDLFYLFPFSLMGFPQSVKTASDLR-TSKHFLSLLTNFAHFGN 608
            GK+RGR + +      +S+ ++PY  PP G+LRF  P P  + W+   D A +    C+Q    +P +   +G EDCL ++V+ P      KR+ FPV+   HGGAF  G+  +   G E  +  G  +LV ++YR+GPLGF+S    D PGN GL+DQ LAL W ++++  FGG+  NV L+G SAG  S  L ++            + SG A   ++    A    G+AF   R +G + A+  + + +CL+  P   ++     F  +      P+ P+++   A    + Q   D+I+SG   + +P    Y +E+G   +A   K ++     D L  +W   AP LLF R  D  TK D    S +IK+++   + F   S S L+R   LF+  +F+   ++ LDL  ++G S  +AYV+       +  +                  A       G  HGDD F +F      F + V+   D +  S++F+++L +FA   N
Sbjct:   35 GKLRGRDNGS-----YYSYESIPYAEPPTGDLRFEAPEPYKQKWSDIFD-ATKTPVACLQWDQFTPGANKLVGEEDCLTVSVYKPK---NSKRNSFPVVAHIHGGAFMFGA--AWQNGHENVMREGKFILVKISYRLGPLGFVSTGDRDLPGNYGLKDQRLALKWIKQNIASFGGEPQNVLLVGHSAGGASVHLQMLREDFGQLARAAFSFSGNALDPWVIQKGA---RGRAFELGRNVGCESAEDSTSLKKCLKSKPASELVTAVRKFLIFSYVPFAPFSPVLEPSDAPDAIITQDPRDVIKSGKFGQ-VPWAVSYVTEDGGYNAALLLKERKSGIVIDDLNERWLELAPYLLFYR--DTKTKKDMDDYSRKIKQEYIGNQRFDIESYSELQR---LFTDILFKNSTQESLDLHRKYGKSPAYAYVYDNPAEKGIAQVL-----------------ANRTDYDFGTVHGDDYFLIFE----NFVRDVEMRPDEQIISRNFINMLADFASSDN 506          

Query:  106 GKIRGRRSQTRNGRPIFSFRALPYGVPPLGELRFRPPLPVEPWAGSLDGAGRESPQCIQVSVLSPESKMYLGSEDCLYLNVFTPHLPGAGKRSLFPVMVFFHGGAFNVGSNDSRLYGPEYWLDYG-VVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCASTSFLHNDRAPSVYGKAF--ARALGIDVAQSESDILECLQKVPIKSIMDKSTVFKDWDVTNPLPWKPIVDGQFATQPFLPQPFEDLIRSGFANKAIPVLSGYTSEEGLILSAFFHKSQRRW---DLLFNQWEIWAPQLLFNRESDLVTKADQSCVS-QIKEKFFPGEGFPARSESNLKRLEQLFSLAIFQAPLRKDLDLLSEHGFS-IFAYVFQYEGSMSMVDLFRLPILKMLLNFSGRHLGARLYQKRLGVCHGDDLFYLFPFSLMGFPQSVKTASDLR-TSKHFLSLLTNFAHFGN 608
            GK+RGR + +      +S+ ++PY  PP+G+LRF  P P +     +  A +    C+Q    +P +   +G EDCL ++++ P      KRS FPV+   HGGAF  G+  +   G E  +  G  +LV ++YR+GPLGF S    D PGN GL+DQ LAL W ++++  FGG+  N+ L+G SAG  S  L ++            + SG A   ++    A    G+AF   R +G + ++  + + +CL+  P   ++     F  +      P+ P+++   A   FL Q   ++I+SG   + +P    Y +E+G   +A   K ++     D L ++W   AP  LF R  D  TK D    S +IKE +   + F   S S L+R   LF+  +F+   ++ LDL  ++G S  +AYV+       +  +                  A       G  HGDD F +F      F + V+   D    S++F+++L +FA   N
Sbjct:   33 GKLRGRDNGS-----YYSYESIPYAEPPIGDLRFEAPEPYKQKWSDIFEATKTPVACLQWDQFTPGANKLVGEEDCLTVSIYKPK---NSKRSSFPVVAHIHGGAFMFGA--AWQNGHENVMREGKFILVKISYRLGPLGFASTGDRDLPGNYGLKDQRLALKWIKQNIASFGGEPENILLIGHSAGGASVHLQMLREDFGQLAKAAFSFSGNALDPWVVQKGA---RGRAFELGRNVGCESSEDSASLKKCLKSKPASELVTAVRKFLIFSYVPFAPFSPVLEPSDAPDAFLTQDPREVIKSGKFGQ-VPWAVSYVTEDGGYNAALLLKERKSGIAIDDLNDRWLELAPYFLFYR--DTKTKKDMDDYSRKIKEDYLGNQKFDIESYSELQR---LFTDILFKNSTQESLDLHRKYGKSPAYAYVYDNPAEKGIAQVL-----------------ANRTDYDFGTVHGDDYFLIFE----NFVREVEMRPDEEIISRNFINMLADFASSDN 504          

Query:   75 VIKVQICLWEEHCRESLPGRLAIMTVVLTRL--GKIRGRRSQTRNGRPIFSFRALPYGVPPLGELRFRPPLPV-EPWAGSLDGAGRESPQCIQVSVLSPESKMYLGSEDCLYLNVFTPHLPGAGKRSLFPVMVFFHGGAFNVGSNDSRLYGPEYWLDYG-VVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCASTSFLHNDRAPSVY-----GKAF--ARALGIDVAQSESDILECLQKVPIKSIMDKSTVFKDWDVTNPLPWKPIVDGQFATQPFLPQPFEDLIRSG-FANKAIPVLSGYTSEEGLILSAFFHKSQ----RRWDLLFN-QWEIWAPQLLFNRESDLVTKADQSCVSQIKEKFFPGEGFPARSESNLKRLEQLFSLAIFQAPLRKDLDLLSEHGFS-IFAYVFQYEGSMSMVDLFRLPILKMLLNFSGRHLGARLYQKRLGVCHGDDLFYLFPFSLMGFPQSVKTASDLRTSKHFLSLLTNFA-------HFGNPTPQNKMG 616
            +++  ICL +   +    G + ++  +L  +  GK+RGR     NG   +S+ A+PY  PP GELRF  P P  + W  + D A +    C+Q +     +   LG EDCL ++V+ P       R+ FPV+   HGGAF  G      YG E  +  G V+LVT+ YR+GPLGF+S    D  GN GL+DQ LAL W ++++  FGG+  N+ ++G SAG  S  +HL   M R  F KV      A+ SF  N   P V      G+ F   R +G   A     + +CL+  P   I+     F  +      P+ P ++   A + F+ Q   D+I+SG FA   +P    YT+E+G   +A   + Q    R   L  N +W  WAP LLF R+S    K       ++++++     F   S  +++R   +F+  +F+  +   +DL  ++G S ++A+V+     + +  +            SGR+          G  HGDD+F +F  S   F  + +   +   S++F+ +L  FA        +G+   QN +G
Sbjct:    3 LVRWLICLIQLWIQLGAAGSVTLLDPLLIEIPNGKLRGRD----NGH-YYSYEAIPYAEPPTGELRFEVPKPYKQQWTNTFD-ATQPPVLCMQWNQFINGTNKLLGVEDCLTVSVYRPK---NSSRNNFPVVANLHGGAFMFGGPSQ--YGHENIMREGSVILVTIGYRLGPLGFVSTGDADLSGNFGLKDQRLALLWIKQNIASFGGEPENILVVGHSAGGAS--VHL--QMLREDFSKVAK----AAISFSGNALDPWVIQQGLRGRTFELGRIVGCGQASDSVTLKKCLKSKPASEIVSAVQSFLVFSYVPFTPFGPAIESPDAPEAFITQHPIDIIKSGKFAQ--VPWAVTYTTEDGGYNAALLLEKQASSGRELILDLNDRWFDWAPYLLFYRDSMTTIKDMDDYSRKLRQEYLGDRRFSVESYWDVQR---MFTDLLFKNSVTVSVDLHRKYGKSPVYAFVYDNPAEVGVGQI-----------LSGRN------DVYFGTVHGDDVFLIFNVS---FVPANRRPDEQIISRNFIKMLEYFALSTNDTMAYGDCVFQNNVG 525          

Query:  106 GKIRGRRSQTRNGRPIFSFRALPYGVPPLGELRFRPPLPV-EPWAGSLDGAGRESPQCIQVSVLSPESKMYLGSEDCLYLNVFTPHLPGAGKRSLFPVMVFFHGGAFNVGSNDSRLYGPEYWLDYG-VVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCASTSFLHNDRAPSVY-----GKAF--ARALGIDVAQSESDILECLQKVPIKSIMDKSTVFKDWDVTNPLPWKPIVDGQFATQPFLPQPFEDLIRSG-FANKAIPVLSGYTSEEGLILSAFFHKSQ----RRWDLLFN-QWEIWAPQLLFNRESDLVTKADQSCVSQIKEKFFPGEGFPARSESNLKRLEQLFSLAIFQAPLRKDLDLLSEHGFS-IFAYVFQYEGSMSMVDLFRLPILKMLLNFSGRHLGARLYQKRLGVCHGDDLFYLFPFSLMGFPQSVKTASDLRT-SKHFLSLLTNFAHFGNPT 610
            GK+RGR     NG   +S+ +LPY  PP+G+LRF  P P  + W  + D A +    C+Q            G+EDCL ++V+ P       R+ FPV+   HGGAF  G       G E ++  G ++LV ++YR+GPLGF+S    D  GN GL+DQ LAL W ++++  FGG+  N+ ++G SAG  S  L ++    R  F KV      A+ SF  N   P V      G+AF   R +G   A     + +CL+  P   I+     F  +      P+ P+V+   A + F+ Q   D+I+SG FA   +P    YT+E+G   +A   + Q    R W +  N +W  WAP LLF R+S    K       ++++++     F   S  +L+R   LF+  +F+      LDL  +HG S ++A+V+    +  +                G+ L  R      G  HGDD F +F  +++  PQ     SD  T S++FL +L +F    N T
Sbjct:   33 GKLRGRD----NGN-YYSYESLPYAEPPVGDLRFEAPQPYKQQWTDTFD-ATQPPVSCMQWDQFIRGDDKLAGNEDCLTVSVYRPK---NSSRNSFPVVAQIHGGAFMFGGASQN--GHENFMREGNLILVKISYRLGPLGFVSTGDADLSGNFGLKDQRLALLWIKQNIASFGGEPENILVIGHSAGGGSVHLQVL----REDFSKVAK----AAISFSGNALDPWVVQQGGRGRAFELGRIVGCGQASDSVTLKKCLKSKPASEIVSAVRNFLVFAYVPFTPFGPVVESPDAPEAFISQHPVDIIKSGKFAQ--VPWAVTYTTEDGGYNAALLLEEQASSGREWIVDLNDRWFDWAPYLLFYRDSMTTIKDMDDYSRKLRQEYLGDRRFSVESYWDLQR---LFTDVLFKNSTEISLDLHRKHGKSPVYAFVYDNPANTGI----------------GQGLAQRT-DINFGTVHGDDYFLIFE-NIVREPQ---LRSDEETISRNFLKMLNDFVLSENGT 509          

Query:  106 GKIRGRRSQTRNGRPIFSFRALPYGVPPLGELRFRPPLPV-EPWAGSLDGAGRESPQCIQVSVLSPESKMYLGSEDCLYLNVFTPHLPGAGKRSLFPVMVFFHGGAFNVGSNDSRLYGPEYWLDYG-VVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCASTSFLHNDRAPSVYGKAF--ARALGIDVAQSESDILECLQKVPIKSIMDKSTVFKDWDVTNPLPWKPIVDGQFATQPFLPQPFEDLIRSGFANKAIPVLSGYTSEEGLILSAFFHKSQRRW---DLLFNQWEIWAPQLLFNRESDLVTKADQSCVS-QIKEKFFPGEGFPARSESNLKRLEQLFSLAIFQAPLRKDLDLLSEHGFS-IFAYVFQYEGSMSMVDLFRLPILKMLLNFSGRHLGARLYQKRLGVCHGDDLFYLFPFSLMGFPQSVKTASDLR-TSKHFLSLLTNFAHFGN 608
            GK+RGR + +      +S+ ++PY  PP G+LRF  P P  + W+   D A +    C+Q    +P +   +G EDCL ++++ P      KRS FPV+   HGGAF  G+  +   G E  +  G  +LV ++YR+GPLGF S    D PGN GL+DQ LAL W ++++  FGG+  NV L+G SAG  S  L ++            + SG A   ++    A    G+AF   R +G + A+  + + +CL+      ++     F  +      P+ P+++   A    L Q   ++I+SG   + +P    Y +E+G   +A   K ++     D L ++W   AP  LF R  D  TK D    S +IKE +   + F   S S L+R   LF+  +F+   ++ LDL  ++G S  +AYV+       +  +                  A       G  HGDD F +F      F + V+   D    S++F+++L +FA   N
Sbjct:   33 GKLRGRDNGS-----YYSYESIPYAEPPTGDLRFEAPEPYKQKWSDIFD-ATKTPVACLQWDQFTPGANKLVGEEDCLTVSIYKPK---NSKRSTFPVVAHIHGGAFMFGA--AWQNGHENVMREGKFILVKISYRLGPLGFASTGDRDLPGNYGLKDQRLALKWIKQNIASFGGEPQNVLLIGHSAGGASVHLQMLREDFGQLAKAAFSFSGNALDPWVVQKGA---RGRAFELGRNVGCESAEDSASLKKCLKSKSASELVTAVRKFLIFSYVPFAPFSPVLEPSDAPDAILTQDPREVIKSGKFGQ-VPWAVSYVTEDGGYNAALLLKERKSGIVIDDLNDRWLELAPYFLFYR--DTKTKKDMDDYSRKIKEDYLGNQKFDIESYSELQR---LFTDILFKNSTQESLDLHRKYGKSPAYAYVYDNPAEKGIAQVL-----------------ANRTDYDFGTVHGDDYFLIFE----NFVREVEMRPDEEIISRNFINMLADFASSDN 504          

Query:   75 VIKVQICLWEEHCRESLPGRLAIMTVVLTRL--GKIRGRRSQTRNGRPIFSFRALPYGVPPLGELRFRPPLPV-EPWAGSLDGAGRESPQCIQVSVLSPESKMYLGSEDCLYLNVFTPHLPGAGKRSLFPVMVFFHGGAFNVGSNDSRLYGPEYWLDYG-VVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCASTSFLHNDRAPSVYGKAF--ARALGIDVAQSESDILECLQKVPIKSIMDKSTVFKDWDVTNPLPWKPIVDGQFATQPFLPQPFEDLIRSGFANKAIPVLSGYTSEEGLILSAFFHKSQRRWDL-----LFNQWEIWAPQLLFNRESDLVTKADQSCVSQIKEKFFPGEGFPARSESNLKRLEQLFSLAIFQAPLRKDLDLLSEHGFS-IFAYVFQYEGSMSMVDLFRLPILKMLLNFSGRHLGARLYQKRLGVCHGDDLFYLFPFSLMGFPQSVKTASDLRTSKHFLSLLTNFA-------HFGNPTPQNKMG 616
            +++  ICL +   +    G + ++  +L  +  GK+RGR     NG   +S+ A+PY  PP GELRF  P P  + W  + D A +    C+Q +     +   LG EDCL ++V+ P       R+ FPV+   HGGAF  G      YG E  +  G V+LVT+ YR+GPLGF+S    D  GN GL+DQ LAL W ++++  FGG+  N+ ++G SAG  S  L ++           I+ SG A   ++       + G+AF   R +G   A     + +CL+  P   I+     F  +      P+ P ++   A + F+ Q   D+I+SG  ++ +P    YT+E+G   +A   + Q          L ++W  WAP LLF R+S    K       ++++++     F   S  +++R   +F+  +F+  +   +DL  ++G S ++A+V+     + +  +            SGR+          G  HGDD+F +F  S +  P + +   ++  S++F+ +L  FA        +G+   QN +G
Sbjct:    3 LVRWLICLIQLWVQLGAAGSVTLLDPLLIEIPNGKLRGRD----NGH-YYSYEAIPYAEPPTGELRFEVPKPYKQQWTNTFD-ATQPPVLCMQWNQFINGTNKLLGVEDCLTVSVYRPK---NSSRNNFPVVANLHGGAFMFGGPSQ--YGHENIMREGSVILVTIGYRLGPLGFVSTGDADLSGNFGLKDQRLALLWIKQNIASFGGEPENILVVGHSAGGASVHLQMLREDFSKLAKAAISFSGNALDPWVIQQ---GLRGRAFELGRIVGCGQASDSGTLKKCLKSKPAIEIVSAVRSFLVFSYVPFTPFGPAIESPDAPEAFITQHPIDIIKSGKFSQ-VPWAVTYTTEDGGYNAALLLEKQASSGRELIVDLNDRWFDWAPYLLFYRDSMTTIKDMDDYSRKLRQEYLGDRRFSVESYWDVQR---MFTDLLFKNSVTVSVDLHRKYGKSPVYAFVYDNPSEVGVGQI-----------LSGRN------DVYFGTVHGDDVFLIFNVSFV--PANRRPDEEI-ISRNFIKMLEYFALSTDDTMAYGDCVFQNNVG 525          

Query:  100 VVLTRLGKIRGRRSQTRNGRPIFSFRALPYGVPPLGELRFRPPLPVEPWAGSLDGAGRESPQCIQVSVLSPESKMYLGSEDCLYLNVFTPHLPGAG---KRSLFPVMVFFHGGAFNVGSNDSRLYGPEYWLDYGVVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCASTSFLHNDRAPSVYGKAFARALGIDVAQSESDILECLQKVPIKSIMDKSTVFKDWDVTNPLPWKPIVDGQFATQPFLPQPFEDLIRSGFANKAIPVLSGYTSEEGLILSAFFHKSQRRWDLLFNQWEIWAPQLLFNRESDLVTKADQSCVSQIKEKFFPGEGFPARSESNLKRLEQLFSLAIFQAPLRKDLDLLSEHGFSIFAYVFQYEGSMSMVDLFRLPILKMLLNFSGRHLGARLYQKRLGVCHGDDLFYLFPFSLMGFPQSVKTASDLRTSKHFLSLLTNFAHFGNPTPQNKMGFLWEPWTKTSNAQLRIGSGLVMEI----DPLVEKRIQFWNQLTTINRFQTSHKPIIHLHSAIAERR 678
            VV T  G I+GRR++T  GR IFSF  +PY   P+G LRFR   P +PW G LD  G   P CIQ ++  P S+  +GSEDCLYLNV+TP L  AG     +L PV++F HGGAF VGSNDSRLYGPE  LD  +VLV +NYR+G LGFLSLET+ +PGNLGL DQ L+L W Q+++  FGG+ +NVTL+GESAGAMS  LH VSP S G FH+VIALSG  ST FL  +R P  Y  A A  LG    +    IL+ LQ V +  IM   T+F DWD   P+PW P VD  F +QPFLPQ F + ++SG     +PVL  +  +EGL+L++ FHK   R ++L   W+ WAP L  N+E ++ T  D + V +IK+ +F      + +ES  ++L+ + S++ F  PL +D  LL++H + +         + S++ + R P L+++L  SG+ +G   ++K  GVCHGDDL ++FPF + GFP+ VKT       K  +S+L NF+   +P      GF  E    + +  + I  G V+      +  + ++++FW Q++ ++R  +S KP    +S     R
Sbjct:    9 VVETSTGWIKGRRTKTDLGRKIFSFTGIPYAKAPIGPLRFRRSSPCDPWYGCLDTTGVSEP-CIQPNMFFPTSRFRMGSEDCLYLNVYTPTLSQAGPGENENLKPVLIFIHGGAFAVGSNDSRLYGPEILLDQDLVLVCMNYRLGTLGFLSLETERSPGNLGLHDQYLSLLWVQQNIQKFGGNPDNVTLMGESAGAMSALLHAVSPFSSGLFHRVIALSGTPSTVFLRPNRRPVQYALALAERLGCQ-DKDPDRILDYLQTVSVDRIMKHCTMFMDWDYPIPMPWIPTVDS-FCSQPFLPQDFTEAVKSGLGT-PVPVLYCFCKDEGLLLTSPFHKEPERIEILRKDWDSWAPLLFLNKEREIHTPEDLTTVRRIKQYYFGNSELDSSNES-FEKLKDIHSMSYFVQPLLQDAALLAKHNWPLSIMRLSVPPAFSIIHILRNPFLEVVLKLSGKAVGLGYFKKSYGVCHGDDLAFIFPFKVPGFPEFVKTKDQKFARKTLISVLVNFSESRSPF----FGFS-EELVGSPDGFVNIEPGEVLNYVKVNESEISEQVRFWEQISQVDRRVSSRKPFAKFYSQTPPYR 584          

Query:  101 VLTRLGKIRGRRSQTRNGRPIFSFRALPYGVPPLGELRFRPPLPVEPWAGSLDGAGRESPQCIQVSVLSPESKMYL--GSEDCLYLNVFTPHLPGAGKRSLFPVMVFFHGGAFNVGSNDSRLYGPEYWLDYGVVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCASTSFLHNDRAPSVYGKAFARALGIDVAQSESDILECLQKVPIKSIMDKSTVFKDWDVTNPLPWKPIVDGQFATQPFLPQPF 399
            ++++ G+I+G R +T +G+ IF FR +PY +PP+G+LRFR   P   W G  DG  +ES + +Q +VL+P+ K YL  G EDCLYLNV+T  L    K    PV+VF HGGAF VGS +S LYGP+  L+  +VLV  NYR+G LG L+LETD+ PGNLGL DQ LAL W  E++  FGGD +N++L+GESAG+MS  LHLVSP+S+G FH+VIALSG  +T+FLH DR P +Y  A A  LG +  +    +L  LQ VP KSI+  ST+F+DWD ++P+PW P +D   A +P +P+ +
Sbjct:   30 IISKCGEIKGSRLKTNSGKNIFCFRGIPYALPPVGQLRFRRSRPYGAWTGIWDGT-KESKKSLQPNVLAPD-KHYLSEGDEDCLYLNVYTKTLDDTAK---LPVVVFIHGGAFAVGSCESLLYGPQILLEKDIVLVGFNYRLGTLGSLTLETDECPGNLGLHDQFLALQWINENITEFGGDISNISLMGESAGSMSALLHLVSPVSQGLFHRVIALSGTPTTTFLHKDRRPRLYALAVAEKLGCEDLEDFDKVLLFLQSVPAKSILKLSTLFQDWDASHPMPWVPCLDTH-AAEPMVPRGY 324          

Query:  100 VVLTRLGKIRGRRSQTRNGRPIFSFRALPYGVPPLGELRFRPPLPVEPWAGSLDGAGRESPQCIQVSVLSPESKMYLGSEDCLYLNVFTPHLPG--AGKRSLFPVMVFFHGGAFNVGSNDSRLYGPEYWLDYGVVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCASTSFLHNDRAPSVYGK-AFARALGIDVAQSES-DILECLQKVPIKSIMDKSTVFKDWDVTNPLPWKPIVD----GQFATQPFLPQPFEDLIRSGFANKAIPVLSGYTSEEGLILSAFFHKSQRRWDLLFNQWEIWAPQLLFNRESDLVTKADQSCVSQIKEKFFPGEGFPARSESNLKRLEQLFSLAIFQAPLRKDLDL-LSEHGFSIFAYVFQYEGSMSMVDLFRLPILKMLLNFSGRHLGARLYQKRLGVCHGDDLFYLFPFSLMGFPQSVKTASDLRTSKHFLSLLTNFAHFGNPTPQNKMGFLWEPWTKTSNAQ-LRIGSGLVMEIDPLVEKRIQFWNQL 654
             VLT LG+IRG   +TR GR I +F  +PY +PPLG+ RF+ P+P+EPW  +LD A + +P C+Q +      K  +G EDCLYLN++TP+       + +L PVMVF HGG +  G + + +YGPEY LD  V+LVT+NYR+GPLGFLS + +  PGN GL+DQ  AL + Q+ +  FGGD+N+VTL GESAG  S   H++SP S+G FHKVI+ SG A   +   + AP    K AF  A  +   Q+ S +++ECL+      I+     F  WD     P+K +V+    G F TQ   P+ F  +        ++P L+G T +EG + + +  K++ R+    + ++  AP   +   S  V +  ++    +++K+   +   A ++     L Q+++ + F  P  + L+L  +    S++ Y   YE S S   +F                     ++++GVCH DDL YLFP   +    S K   D+  SK  ++L TNFA  GNP     + F WEP T     + L+I +   M+ D     R +FW  L
Sbjct:   29 TVLTPLGEIRGYHMKTREGREISAFTGIPYAIPPLGDSRFKAPVPIEPWKETLD-ATQPTPVCVQRNPYI-RQKDIIGQEDCLYLNIYTPYTSNDLIHENNLLPVMVFIHGGGWMCGDSTTAMYGPEYLLDRDVILVTINYRLGPLGFLSTQDEHCPGNNGLKDQQEALRFIQKTILSFGGDKNSVTLFGESAGGASAHFHMLSPTSQGLFHKVISESGTALVPWA--EAAPGEGLKNAFRLAKFLGCPQAPSRNMIECLRTKDSYDIIGTEFRFYAWDYEPMTPFKAVVEPDLPGAFLTQS--PRKFPKV-------PSVPWLTGLTKDEGCLKTGWIIKNETRYKEFLSGFDAIAPVTFYYDNSPHVAEITKA----VRKKYKITDDMEASNDG----LLQIYTDSYFAYPAIEALELNFNYTTSSVYLYELAYEASNSFSQIFGYG------------------EEKVGVCHADDLMYLFPIHFLSKQPSRK---DIEMSKLIITLWTNFASSGNPNKPKVLPFKWEPATNGLTMEYLQIDANPSMKQD--FASRSRFWATL 549          

Query:  100 VVLTRLGKIRGRRSQTRNGRPIFSFRALPYGVPPLGELRFRPPLPVEPWAGSLDGAGRESPQCIQVSVLSPESKMYLGSEDCLYLNVFTPHLPG--AGKRSLFPVMVFFHGGAFNVGSNDSRLYGPEYWLDYGVVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCASTSFLHNDRAPSVYGKAFARALGIDVAQSES-DILECLQKVPIKSIMDKSTVFKDWDVTNPLPWKPIVDGQFATQPFLPQPFEDLIRSGFAN-KAIPVLSGYTSEEGLILSAFFHKSQRRWDLLFNQWEIWAPQLLFNRESDLVTKADQSCVSQIKEKFFPGEGFPARSESNLKRLEQ----LFSLAIFQAPLRKDLDLLSEHGFS-IFAYVFQYEGSMSMVDLFRLPILKMLLNFSGRHLGARLYQKRLGVCHGDDLFYLFPFSLMGFPQSVKTASDLRTSKHFLSLLTNFAHFGNPTPQNKMGFLWEPWTKTSNAQ-LRIGSGLVMEIDPLVEKRIQFWNQL 654
            VV T LG++ G   QTR GR I +F A+P+ VPP+G+LRF+ P+PVEPW  +LD A +ESP C+Q +  + + ++ +G EDCLYLN++TP        K+ L PVMVF HGG +  GS  + +YGP++ LD  VV V  NYR+GPLGFLS + ++ PGN GL+DQ  AL + Q+ V  FGGD N+VT+ GESAG  S   H++S  S G FHK I+ SG A   +       ++   AF  A  +D  Q+ S  ++ECL+      I+     F  WD     P+K +V      +P LP  F         N  A+P ++G T +EG + S +    + R++   + +E  AP   +   S    +  Q    +I+ K+F         E++L+  +Q    ++S + F  P  + ++L+  +  + ++ Y   Y G+ S   +F  P                  Q   GVCH DDL +LFP   +  P S     DL+ S+  ++L TNFA  GNP     + F WE  T  S  + L +G    M+ D  +  R +FW +L
Sbjct:   29 VVRTPLGEVAGYYMQTRGGRQIAAFTAIPFAVPPVGDLRFKAPVPVEPWQDTLD-ATKESPVCVQRNPYTRQEEI-VGQEDCLYLNIYTPITDNDVGEKKKLLPVMVFLHGGGWMCGSGTTEMYGPQFLLDRDVVFVATNYRLGPLGFLSTQDENCPGNNGLKDQQEALRFLQKTVESFGGDPNSVTIFGESAGGASVHYHMISESSAGLFHKGISESGTALVPWAEAPPGEALR-NAFLLAKYLDCPQAPSAKMIECLRTKDSYDIIGTEFSFYKWDYEPMTPFKAVV------EPDLPGAFLTRSPRKVPNVPAVPWMTGLTKDEGCLKSVWITAFEGRYNEFMSGFETIAPVTFYYENSPYAEEITQ----KIRNKYF--------KENDLQATQQGILNIYSDSYFAYPAIEAIELVFNYTKNPVYLYELTYRGANSFSQIFGDP------------------QGDYGVCHADDLMHLFPIGFLSNPFS---PEDLKMSETIVTLWTNFATTGNPNKPVPVPFKWETATSGSKMEYLELGFKPHMKKD--LAPRSRFWGEL 549          

Query:  106 GKIRGRRSQTRNGRPIFSFRALPYGVPPLGELRFRPPLPVEPWAGSLDGAGRESPQCIQVSVLSPESKMYLGSEDCLYLNVFTPHLPGAGKRSLFPVMVFFHGGAFNVGSNDSRLYGPEYWLDYGVVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCASTSFLHNDRAPSVYGKAFARALGIDVAQSESDILECLQKVPIKSIMDKSTVFKDWD---VTNPLPWKPIVDGQFATQPFLPQPFEDLIRSGFANKAIPVLSGYTSEEGLILSAFFHKSQRRWDLLFNQWEIWA--PQLLFNRESDLVTKADQSCVSQIKEKFFPGEGFPARSESNLKRLEQLFSLAIFQAPLRKDLDLLSEHGFSIFAYVFQYEGSMSMVDLFRLPILKMLLNFSGRHLGAR----LYQKRLGVCHGDDLFYLFPFSLMGFPQSVKTASDLRTSKHFLSLLTNFAHFGNPTP-QNKMGFLWEPWTKTSNAQLRIGSG-----LVMEIDPLVEKRIQFWNQL 654
            GKIRG +    NG+  F F  +PY  PP+G+LRF+PP+PVE +   +    +E   C   +   PE++ +  SEDCL+LNV+TP LP +G     PVM++ HGG FN+GS D+ +YGPE+ L   VVLVT NYR+GP+GFL L +    GN+GL+DQ L L W  E+VG FGGD NNVTL GESAG  +  L+ ++  SR +FHK I +SG +   ++     P    +  A  LG D + S+ D+   L K   K ++  S      D    +    + P+++ + + +PFL + F  L+      K IP+++G TS EG++++A           +    E++A  P ++  +E  L          +IK  FF   G  A   S L                   +D++S++ F + AYV     +   ++    P+   L +FSG+    R    + +   GVCH D+L YLF  + MG      +  D +       L TNFA FGNPTP    + F+WEP   TS+ Q  + +      L M  +P +E R+QFW ++
Sbjct:   69 GKIRGVKQVLPNGKNYFRFSGVPYAKPPVGDLRFKPPVPVEKFDHEVLDCQKEGSNCYSSTYYPPEAEEF-ASEDCLFLNVYTPKLPESGDDVNLPVMLWIHGGGFNLGSGDAAVYGPEFLLQEEVVLVTCNYRLGPMGFLCLPSVGIHGNMGLKDQRLVLKWVNENVGRFGGDPNNVTLFGESAGGAAVHLNYLADTSRQYFHKAICMSGVSYNPWVLQSN-PEAKARKLAELLGAD-SVSDDDVCRVLMKASAKDLLQHSPDVLSEDEKRTSKFFAFTPVIESECSVEPFLQENFISLMMKPNMTK-IPMMTGVTSSEGMLVAA----------QMLKDIELYAADPTMMVPQELPLDADRLIEAAGEIKRFFFGDNGITADRLSTL-------------------VDIMSDNMFVMAAYVASELHARYQIE---APLYFYLDSFSGKLNKYRDLFVVPEHLEGVCHADELLYLFSSTWMGTDVEQGSRED-KFRAVMCKLWTNFAKFGNPTPIDGGLDFVWEPVKPTSDLQFVLNAAELNDELKMVENPFLE-RVQFWREI 594          

Query:  101 VLTRLGKIRGRRSQTRNGRPIFSFRALPYGVPPLGELRFRPPLPVEPWAGSLDGAGRESPQCIQVSVLSPESKMYLGSEDCLYLNVFTPHLPGAGKRSLFPVMVFFHGGAFNVGSNDSRLYGPEYWLDYGVVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCASTSFLHNDRAPSVY-GKAFARALGIDVAQSESDILECLQKVPIKSIMDKSTVFKDWDVTNPLPWKPIVDGQFATQPFLPQPFEDLIRSGFANKAIPVLSGYTSEEGLILSAFFHKSQRRWDLLFNQWEIWAPQLLFNRESDLVTKADQSC-VSQIKEKFFPGEGFPARSESNLKRLEQLFSLAIFQAPLRKDL------DLLSEHGFSIFAYVFQYEGSMSMVDLFRLPILKMLLNFSGRHLGARLYQKRLGVCHGDDLFYLFPFSLMGFPQSVKTASDLRTSKHFLSLLTNFAHFGNPTP----QNKMGFLWEPWTKTSNAQ-LRIGSGLVMEIDP-LVEKRIQFWNQL 654
            V  + G +RG    +R GR    F+ +PY  PPLGE+RFR P P E W G  + A   SP CIQ S+ + +  +  GSEDCLYLNVFTP +  + +     VMV+FHGG F  G+     YGPEY LD  +VLVTVNYR+GP+GFLS     APGN GL+DQV ALHW   ++  FGG+ ++VTL GESAG  S   H++SP+SRG FH+ I+ SG A  S+       S +  +  A+ L    + + + ++ECL+    + ++     F +WDV   +P+KP+V+       FLP     L++ G    +IP L+G  S +G + +A  ++       L +Q+E  AP  +F  E   V+  D +  +SQ  + F+  E  P  +E+ + R+  +++ + F     + +      + +   G S++ Y F Y G  S  +LF  P                   +  GVCH D+L YLFP S   F     T  + + +   + + TNFAH GNPTP    ++ M   W+P T   N + L I S   + ++  L++ R++FW+ L
Sbjct:   25 VTVKQGSLRGHYLTSRKGRRFVGFQGVPYAKPPLGEMRFRNPEPPESWVGVRE-ATEYSPVCIQRSIFAKQIDI-TGSEDCLYLNVFTPQVLSSLRMD---VMVWFHGGGFVSGAGS--FYGPEYLLDEDIVLVTVNYRLGPIGFLSTGDVAAPGNFGLKDQVAALHWVHNNIELFGGNPSSVTLFGESAGGSSVHYHMLSPLSRGLFHRGISQSGTALCSWAFAANGSSSHQARKLAKLLDCPTSPN-AGLVECLRTKDARDVIATDKQFMEWDVDPLIPFKPVVEPTGLQDAFLPAEPLQLLQKG--PLSIPWLTGINSADGALKAAPIYEKAELVAELNSQFERVAPITMFYGE---VSSPDVAAEISQRIKSFYFKEQ-PIGNET-MHRVVDMYTDSFFSWAANEAVHIHLSRNFVEGDGASVYYYYFTYRGPHSYSELFGDPT------------------RDFGVCHADELIYLFP-SARVFGNFSATPEEEQMTDCLIHMWTNFAHTGNPTPLDTKKDVMSTTWQPVTSIDNLEYLHIESPSNIYMNSGLLKDRVRFWSSL 558          

Query:  101 VLTRLGKIRGRRSQTRNGRPIFSFRALPYGVPPLGELRFRPPLPVEPWAGSLDGAGRESPQCIQVSVLSPESKMYLGSEDCLYLNVFTPHLPG--AGKRSLFPVMVFFHGGAFNVGSNDSRLYGPEYWLDYGVVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCASTSFLHNDRAPSVYGKAFARALGIDVAQSES-DILECLQKVPIKSIMDKSTVFKDWDVTNPLPWKPIVDGQFATQPFLPQPF-EDLIRSGFANKAIPVLSGYTSEEGLILSAFFHKSQRRWDLLFNQWEIWAPQLLFNRES---DLVTKADQSCVSQIKEKFFPGEGFPARSESNLKRLEQLFSLAIFQAPLRKDLD-LLSEHGFSIFAYVFQYEGSMSMVDLFRLPILKMLLNFSGRHLGARLYQKRLGVCHGDDLFYLFPFSLMGFPQSVKTASDLRTSKHFLSLLTNFAHFGNPTPQNKMGFLWEPWTKTSNAQ-LRIGSGLVMEIDPLVEKRIQFWNQL 654
            V T LG+I+G   +TR G+ I +F A+P+ VPP+G+LRF+ P+P+EPW  +LDG  + +P C+Q +  + + ++ +G EDCLYLN++TP          SL PVMVF HGG +  G + + +YGP+Y LD+ V+LVT+NYR+GPLGFLS + +  PGN GL+DQ   L + Q+ +  FGGD+++VT+ GESAG  S   H++S  S G FHK I+ SG A   +       ++   AF  A  ++  Q+ S D+++CL+      I++    F  WD     P+K +V      +P LP  F     R      A+P ++G   +EG + S +   ++ R+    + ++I AP   +   S   D++T+       +IKE +     F A  +  L    +++S + F  P  + ++  L+     I+ Y   Y G+ S  ++F  PI                     GVCH D+L YLFP   +  P S K   DL   +   ++ TNFA  GNP     +   WEP T  +  + L I S   M+ +  + +R +FW +L
Sbjct:   33 VNTPLGEIKGSYMKTREGKEISAFTAIPFAVPPVGDLRFKAPVPIEPWKETLDGT-KTTPACVQRNPYTRQKEI-VGQEDCLYLNIYTPRTSNDLIKDGSLLPVMVFLHGGGWMCGDSTTSMYGPDYLLDHEVILVTINYRLGPLGFLSTQDEQCPGNNGLKDQQEGLRFIQKVIESFGGDKDSVTIFGESAGGASVHYHMLSKTSTGLFHKAISESGSALVPWAEAPPGEALR-NAFQLAKFLECPQAPSADMIKCLRTKDSYDIINTEFNFYVWDYEPMTPFKAVV------EPDLPGAFLTQSARKVTDVPAVPWMTGLNKDEGCLKSVWITNNETRYKEFTSGFDIIAPVTFYYDNSPYADIITR-------KIKENYLKDGSFEAMRQGIL----EIYSDSYFSYPALEAVEHTLTYSKSPIYLYELAYRGTSSFSEIFGDPI------------------GDYGVCHADELMYLFPTRFLTKPASPK---DLEMGRLIRTMWTNFATSGNPNKPVPIPVSWEPATSGNKLEYLEIASQSTMKYN--LAERSRFWGKL 552          

Query:  106 GKIRGRRSQTRNGRPIFSFRALPYGVPPLGELRFRPPLPVEPWAGSLDGAGRESPQCIQVSVLSPESKMYLGSEDCLYLNVFTPHLPGAGKRSLFPVMVFFHGGAFNVGSNDSRLYGPEYWLDYGVVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCASTSFLHNDRAPSVYGKAFARALGIDVAQSESDILECLQKVPIKSIMDKSTVFKDWD---VTNPLPWKPIVDGQFATQPFLPQPFEDLIRSGFANKAIPVLSGYTSEEGLILSAFFHKSQRRWDLLFNQWEIWA--PQLLFNRESDLVTKADQSCVSQIKEKFFPGEGFPARSESNLKRL--EQLFSLAIFQAPLRKDLDLLSEHGFSIFAYVFQYEGSMSMV-DLFRLPILKMLLNFSGRHLGARLYQKRLGVCHGDDLFYLFPFSLMGFPQSVKTASDLRTSKHFLSLLTNFAHFGNPTPQN-KMGFLWEPWTKTSNAQLRIGSG-----LVMEIDPLVEKRIQFWNQL 654
            GKIRG +    NG+  F F  +PY  PP+G+LRF+PP+PVE +   +    +E   C   +   PE++ +  SE+CL+LNV+TP LP +G     PVM++ HGG FN+GS D+ +YGPE+ L   VVLVT NYR+GP+GFL L +    GN+GL+DQ L L W  E+VG FGGD NNVTL GESAG  +  L+ ++  SR +FHK I +SG +   ++     P    +  A  LG D + S+ D+ + L K   K ++  S      D    +    + P+++ + + +PFL + F  L+      K IP+++G TS EG++++A           +    E++A  P ++  +E  L          +IK  FF      A   S L  +  + +F +A + A    +L    ++   ++ Y+  + G ++   DLF +P           HL         GVCH D+L YLF  + MG      +  D +       L TNFA FGNPTP +  + F+WEP   TS+ Q  + +      L M  +P +E R+QFW ++
Sbjct:   68 GKIRGVKQVLPNGKNYFRFSGVPYAKPPVGDLRFKPPVPVENFDHEVLDCQQEGSNCYSSTYYPPEAEEF-ASENCLFLNVYTPKLPESGDDVNLPVMLWIHGGGFNLGSGDAAVYGPEFLLQEEVVLVTCNYRLGPMGFLCLPSVGIHGNMGLKDQRLVLKWVNENVGRFGGDPNNVTLFGESAGGAAVHLNYLADSSRQYFHKAICMSGVSYNPWVLQSN-PEAKARKLAELLGAD-SVSDDDVYQALMKASAKDLLQHSPDVLSEDEKRTSKFFAFTPVIESECSVEPFLQENFISLMMKPNMTK-IPMMTGVTSSEGMLVAA----------QMLKDIELYAADPTMMVPQELPLDADRLIEAAGEIKRFFFGDNDIIADRLSTLVDIMSDNMFVMAAYVA---SELHARYQNEAPLYFYLDSFSGKLNKYRDLFVVP----------EHLE--------GVCHADELLYLFSSTWMGTDVEQGSRED-KFRAVMCKLWTNFAKFGNPTPTDGGLDFVWEPVKPTSDLQFVLNAAELNDELKMVENPFLE-RVQFWREM 593          

Query:  100 VVLTRLGKIRGRRSQTRNGRPIFSFRALPYGVPPLGELRFRPPLPVEPWAGSLDGAGRESPQCIQVSVLSPESKMYLGSEDCLYLNVFTPHL---PGAGKRSLFPVMVFFHGGAFNVGSNDSRLYGPEYWLDYGVVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCASTSFLHNDRAPS-VYGKAFARALGIDVAQSESDILECLQ-KVPIKSIMDKSTVFKDWDVTNPLPWKPIVDGQFATQPFLPQPFEDLIRSGFANKAIPVLSGYTSEEGLILSA--FFHKSQRRW--DLLFNQWEIWAPQLLFNRESDLVTKADQSCVSQIKEKFFPGEGFPARSESNLKRLEQLFSLAIFQAPLRKDLDL-LSEHGFSIFAYVFQYEGSMSMVDLFRLPILKMLLNFSGRHLGARLYQKRLGVCHGDDLFYLFPFSLMGFPQSVKTASDLRTSKHFLSLLTNFAHFGNPTPQ--NKMGFLWEPWTKTSNAQLRIGSGLVMEI-DPLVEKRIQFWNQL 654
            VV  + G+++G   +TR GR I +FR +PY +PP+GELRF  P PV  W+G+   A  ++  C+Q +V + E++ + G+EDCLYLNV+TP +         + +PVMV+ HGG +  GS+DS LY P++ LD  V+LV+ NYR+GPLGFLS   +  PGN GL+DQVLAL W +E++  FGGD+N+VT+ GESAG  S    ++SP+++G FH+VI+ SG A   +     A +    +  A+ L   V  SE  + +CLQ K PI+ +      ++ +     +P+KP+V+       FL Q   ++++SG     IP ++G+TS EG + +A  + H   + +   L  N  E+     +++   ++ +K   + +++   +F+ G    A  ES    L  ++S A+F     K ++  L   G  I+ Y   Y GS S   +F                G R Y    GVCH DDL YLFP   +  P SV T  D +      +L  NFA  GNPTP+   ++   W+P   +++  L I S   M + + L++ R+QFW  L
Sbjct:   25 VVKIQHGRLQGTYMRTRKGREISAFRGIPYALPPIGELRFELPQPVSSWSGT-RSAEHDAAVCVQNNVFAGENE-FFGTEDCLYLNVYTPKVSDFENEHDETRYPVMVWVHGGGWMCGSSDSLLYNPKFLLDKDVILVSFNYRLGPLGFLSTADEVLPGNQGLKDQVLALKWIRENIAAFGGDKNSVTIFGESAGGASTHYLMLSPLAKGLFHRVISQSGTALAPWSRTTPAAAKKQAQRLAKQLNCPVEPSEK-LRDCLQHKDPIE-VTSADVEWRIFSYDPVIPFKPVVEPNHPGA-FLAQDPVEILKSGNLTD-IPWMTGFTSHEGALRAANLYGHDDTKHYIQKLANNYLELAPVTFMYD---NVCSKYMHTQIAEKIREFYLGNR--AIDESTRMDLIHMYSDAMFTVNAAKAVEKHLKSLGSPIYYYYLAYRGSNSWSKVFG--------------DGERDY----GVCHCDDLLYLFPQGEVFSPGSVLTEEDGKMVDIMTTLWYNFAKTGNPTPEVTPELPVKWKPVRTSASEYLSIESPQHMRMSENLLKDRLQFWEGL 563          

Query:  100 VVLTRLGKIRGRR--SQTRNGRPIFSFRALPYGVPPLGELRFRPPLPVEPWAGSLDGAGRESPQCIQVSVLSPESKMYLGSEDCLYLNVFTPHLPGA--GKRSLFPVMVFFHGGAFNVGSNDSRLYGPEYWLDYGVVLVTVNYRIGPLGFLSLETDDAPGNLGLRDQVLALHWTQEHVGCFGGDRNNVTLLGESAGAMSNFLHLVSPMSRGFFHKVIALSGCASTSFLHNDRAPSVYGKAFARALGIDVAQSESDILECLQKVP----IKS---IMDKSTVFKDWDVTNPLPWKPIVDGQFATQPFLPQPF-EDLIRSGFANKAIPVLSGYTSEEGLILSAFFHKSQRRWDLLFNQWEIWAPQLL--FNRE------SDLVTKADQSCVSQIKE--KFFPGEGFPARSESNLKRLEQLFSLAIFQAPLRKDLDLLSEHGFSIFAYVFQYEGSMSMVDLFRLPILKMLLNFSGRHLGARLYQKRLGVCHGDDLFYLFPFSLMGFPQSVKTASDLRTSKHFLSLLTNFAHFGNPTP----QNKMGFLWEPWTKTSNAQ-LRIGSGLVMEIDPLVEKRIQFWNQL 654
            VV T+LG++RGRR  ++T N  P +SF+ + Y  PP G LRFRPP P+EPW G  D A  E   C    +L      Y G EDCLYLNV++P LP    G      VMV+ HGGAF VGS +S LYGP++ +  GVVLVT+NYR+G LGFLSLE D+  GN+GL+DQV+AL W ++++  FGGD   VTL GE AGA S  LH++SP S+G FH  IA SG A + +     AP     A  R LGID   S +++L  L+  P    +K+   +   S    D   T  LP+ P+       +P  P  F     R       +P ++GY ++EG+IL   F + QR             P+LL   +RE       +L+  AD++  S + +  + F  +  P  +  NL  L  LF+  +F  P+ + L          + Y F ++G++ +         K +L  +             G CHGD++ YLF FS + + +    + +L  S+  + + TNFA  GNPTP    ++ + F W P   TS  + L I + + ME DP    R+QFW+ L
Sbjct:   52 VVRTQLGELRGRRLITRTNNQTPYYSFKGIRYAQPPRGALRFRPPAPLEPWLGVRD-ALEEGAVCPHRFMLF---DTYKGDEDCLYLNVYSPALPDTLTGYNPKLAVMVWIHGGAFAVGSGNSFLYGPDHLVGAGVVLVTLNYRLGALGFLSLENDEVAGNMGLKDQVMALKWVRDNIEFFGGDPGRVTLFGEPAGAASVHLHMLSPASKGLFHGAIAESGVAISPWALA-AAPRDRAFALGRELGIDT-NSTAELLGYLRATPSELLVKAGARLAGASGPAADLHSTVALPFVPV------GEPPGPDAFLTTAPRDALPGADVPFMTGYNAKEGIIL---FRRLQRY------------PKLLSELDREFRRVVPPELLAGADETLASNVTDLVRSFYFQDRPVDTR-NLDSLIDLFTDVMFLRPVLETLRRPGARRSPTYFYRFAFDGALGL--------FKRMLGITPP-----------GACHGDEMGYLFYFSRLNY-RLDDGSPELAVSRRMVQMWTNFAKTGNPTPPVDYESIVDFKWLPVNDTSTVRYLNIDANVTMEEDP-DGARVQFWDWL 584