BLAST of EMLSAG00000000913 vs. GO
Match: - (symbol:Aph1a "Anterior pharynx defective 1a homolog (C. elegans), isoform CRA_b" species:10116 "Rattus norvegicus" [GO:0001656 "metanephros development" evidence=IEA] [GO:0004175 "endopeptidase activity" evidence=IEA] [GO:0005515 "protein binding" evidence=IPI] [GO:0005783 "endoplasmic reticulum" evidence=IEA] [GO:0005794 "Golgi apparatus" evidence=IEA] [GO:0005887 "integral component of plasma membrane" evidence=IEA] [GO:0006509 "membrane protein ectodomain proteolysis" evidence=IEA] [GO:0007220 "Notch receptor processing" evidence=IEA] [GO:0031293 "membrane protein intracellular domain proteolysis" evidence=IEA] [GO:0042987 "amyloid precursor protein catabolic process" evidence=IEA] [GO:0043085 "positive regulation of catalytic activity" evidence=IEA] InterPro:IPR009294 Pfam:PF06105 RGD:1311546 GO:GO:0005783 GO:GO:0005794 GO:GO:0043085 GO:GO:0005887 GO:GO:0042987 GO:GO:0004175 GO:GO:0006509 GO:GO:0007220 GO:GO:0031293 GO:GO:0016485 CTD:51107 eggNOG:NOG300477 HOGENOM:HOG000007541 HOVERGEN:HBG050541 KO:K06172 GO:GO:0001656 PANTHER:PTHR12889 GeneTree:ENSGT00390000002049 OrthoDB:EOG7TF7B1 EMBL:CH474015 OMA:ACEKRRY EMBL:AABR06019397 EMBL:BC087081 RefSeq:NP_001014277.1 UniGene:Rn.22786 STRING:10116.ENSRNOP00000033566 Ensembl:ENSRNOT00000056289 GeneID:365872 KEGG:rno:365872 UCSC:RGD:1311546 NextBio:688236 Genevestigator:Q5PQQ3 Uniprot:Q5PQQ3)

HSP 1 Score: 144.05 bits (362), Expect = 8.193e-40
Identity = 87/211 (41.23%), Postives = 123/211 (58.29%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEP---------VFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKP---HILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGI 199
            M A  F+G    AFG   A+F+ T+A DP+R+I+LV  +FFWL+S L++S+ WF +V +             +FG   SV  QE+FR   Y LL KA   ++ L+E+    G  P     +AYV G  FGI SG+F ++N+LAD+LGPG +GI G     S ++F+ SA  + AI+L HT WGV+ F ACE ++Y  L  V   H   SG+
Sbjct:    1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVTDRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSED----GRSPISIRQMAYVSGLSFGIISGVFSVINILADALGPGVVGIHGD----SPYYFLTSAFLTAAIILLHTFWGVVFFDACERRRYWALGLVVGSHLLTSGL 203          

BLAST of EMLSAG00000000913 vs. GO
Match: - (symbol:Aph1a "APH1A gamma secretase subunit" species:10116 "Rattus norvegicus" [GO:0001656 "metanephros development" evidence=IEA;ISO] [GO:0004175 "endopeptidase activity" evidence=IEA;ISO] [GO:0005515 "protein binding" evidence=IPI] [GO:0005783 "endoplasmic reticulum" evidence=IEA;ISO] [GO:0005794 "Golgi apparatus" evidence=IEA;ISO] [GO:0005887 "integral component of plasma membrane" evidence=IEA;ISO] [GO:0006509 "membrane protein ectodomain proteolysis" evidence=IEA;ISO] [GO:0007220 "Notch receptor processing" evidence=IEA;ISO] [GO:0016485 "protein processing" evidence=ISO] [GO:0031293 "membrane protein intracellular domain proteolysis" evidence=IEA;ISO] [GO:0042987 "amyloid precursor protein catabolic process" evidence=IEA;ISO] [GO:0043085 "positive regulation of catalytic activity" evidence=IEA;ISO] InterPro:IPR009294 Pfam:PF06105 RGD:1311546 GO:GO:0005783 GO:GO:0005794 GO:GO:0043085 GO:GO:0005887 GO:GO:0042987 GO:GO:0004175 GO:GO:0006509 GO:GO:0007220 GO:GO:0031293 GO:GO:0016485 CTD:51107 eggNOG:NOG300477 HOGENOM:HOG000007541 HOVERGEN:HBG050541 KO:K06172 GO:GO:0001656 PANTHER:PTHR12889 GeneTree:ENSGT00390000002049 OrthoDB:EOG7TF7B1 EMBL:CH474015 OMA:ACEKRRY EMBL:AABR06019397 EMBL:BC087081 RefSeq:NP_001014277.1 UniGene:Rn.22786 STRING:10116.ENSRNOP00000033566 Ensembl:ENSRNOT00000056289 GeneID:365872 KEGG:rno:365872 UCSC:RGD:1311546 NextBio:688236 Genevestigator:Q5PQQ3 Uniprot:Q5PQQ3)

HSP 1 Score: 144.05 bits (362), Expect = 8.193e-40
Identity = 87/211 (41.23%), Postives = 123/211 (58.29%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEP---------VFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKP---HILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGI 199
            M A  F+G    AFG   A+F+ T+A DP+R+I+LV  +FFWL+S L++S+ WF +V +             +FG   SV  QE+FR   Y LL KA   ++ L+E+    G  P     +AYV G  FGI SG+F ++N+LAD+LGPG +GI G     S ++F+ SA  + AI+L HT WGV+ F ACE ++Y  L  V   H   SG+
Sbjct:    1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVTDRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSED----GRSPISIRQMAYVSGLSFGIISGVFSVINILADALGPGVVGIHGD----SPYYFLTSAFLTAAIILLHTFWGVVFFDACERRRYWALGLVVGSHLLTSGL 203          

BLAST of EMLSAG00000000913 vs. GO
Match: - (symbol:APH1A "Uncharacterized protein" species:9913 "Bos taurus" [GO:0001656 "metanephros development" evidence=IEA] [GO:0004175 "endopeptidase activity" evidence=IEA] [GO:0005783 "endoplasmic reticulum" evidence=IEA] [GO:0005794 "Golgi apparatus" evidence=IEA] [GO:0005887 "integral component of plasma membrane" evidence=IEA] [GO:0006509 "membrane protein ectodomain proteolysis" evidence=IEA] [GO:0007220 "Notch receptor processing" evidence=IEA] [GO:0031293 "membrane protein intracellular domain proteolysis" evidence=IEA] [GO:0042987 "amyloid precursor protein catabolic process" evidence=IEA] [GO:0043085 "positive regulation of catalytic activity" evidence=IEA] InterPro:IPR009294 Pfam:PF06105 GO:GO:0005783 GO:GO:0005794 GO:GO:0043085 GO:GO:0005887 GO:GO:0042987 GO:GO:0004175 GO:GO:0006509 GO:GO:0007220 GO:GO:0031293 GO:GO:0016485 CTD:51107 eggNOG:NOG300477 HOGENOM:HOG000007541 HOVERGEN:HBG050541 KO:K06172 OMA:FIAFGPP TreeFam:TF314362 GO:GO:0001656 PANTHER:PTHR12889 GeneTree:ENSGT00390000002049 OrthoDB:EOG7TF7B1 EMBL:DAAA02007262 EMBL:BC103090 RefSeq:NP_001029842.1 UniGene:Bt.48923 STRING:9913.ENSBTAP00000028635 Ensembl:ENSBTAT00000046131 GeneID:539247 KEGG:bta:539247 NextBio:20877875 Uniprot:Q3SZ69)

HSP 1 Score: 144.05 bits (362), Expect = 8.546e-40
Identity = 87/211 (41.23%), Postives = 123/211 (58.29%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEP---------VFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKP---HILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGI 199
            M A  F+G    AFG   A+F+ T+A DP+R+I+LV  +FFWL+S L++S+ WF +V +             +FG   SV  QE+FR   Y LL KA   ++ L+E+    G  P     +AYV G  FGI SG+F ++N+LAD+LGPG +GI G     S ++F+ SA  + AI+L HT WGV+ F ACE ++Y  L  V   H   SG+
Sbjct:    1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVTDRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSED----GRSPISIRQMAYVSGLSFGIISGVFSVINILADALGPGVVGIHGD----SPYYFLTSAFLTAAIILLHTFWGVVFFDACERRRYWALGLVVGSHLLTSGL 203          

BLAST of EMLSAG00000000913 vs. GO
Match: - (symbol:APH1A "Gamma-secretase subunit APH-1A" species:9606 "Homo sapiens" [GO:0001656 "metanephros development" evidence=IEA] [GO:0004175 "endopeptidase activity" evidence=IEA] [GO:0005515 "protein binding" evidence=IPI] [GO:0005783 "endoplasmic reticulum" evidence=IDA] [GO:0005789 "endoplasmic reticulum membrane" evidence=IEA] [GO:0005794 "Golgi apparatus" evidence=IDA] [GO:0005886 "plasma membrane" evidence=TAS] [GO:0005887 "integral component of plasma membrane" evidence=IDA] [GO:0006509 "membrane protein ectodomain proteolysis" evidence=IDA] [GO:0007219 "Notch signaling pathway" evidence=TAS] [GO:0007220 "Notch receptor processing" evidence=IMP;TAS] [GO:0016485 "protein processing" evidence=IDA] [GO:0031293 "membrane protein intracellular domain proteolysis" evidence=IMP;TAS] [GO:0032580 "Golgi cisterna membrane" evidence=IEA] [GO:0042987 "amyloid precursor protein catabolic process" evidence=IMP;TAS] [GO:0043065 "positive regulation of apoptotic process" evidence=TAS] [GO:0043085 "positive regulation of catalytic activity" evidence=IDA] [GO:0048011 "neurotrophin TRK receptor signaling pathway" evidence=TAS] [GO:0097190 "apoptotic signaling pathway" evidence=TAS] Reactome:REACT_691 InterPro:IPR009294 Pfam:PF06105 GO:GO:0005783 GO:GO:0005794 GO:GO:0043085 Reactome:REACT_111102 Reactome:REACT_116125 GO:GO:0048011 GO:GO:0005887 GO:GO:0005789 GO:GO:0032580 GO:GO:0007219 GO:GO:0097190 GO:GO:0043065 GO:GO:0042987 GO:GO:0004175 GO:GO:0006509 GO:GO:0007220 GO:GO:0031293 GO:GO:0016485 EMBL:AL138795 EMBL:CH471121 EMBL:AF508787 EMBL:AY113698 EMBL:AY113699 EMBL:AF151835 EMBL:AY358951 EMBL:AK027879 EMBL:AK075295 EMBL:AK298832 EMBL:BC001230 EMBL:BC008732 EMBL:BC009501 EMBL:BC015568 EMBL:BC017699 EMBL:BC020590 RefSeq:NP_001071096.1 RefSeq:NP_001230700.1 RefSeq:NP_001230701.1 RefSeq:NP_057106.2 UniGene:Hs.108408 UniGene:Hs.735911 ProteinModelPortal:Q96BI3 BioGrid:119296 IntAct:Q96BI3 STRING:9606.ENSP00000358105 BindingDB:Q96BI3 ChEMBL:CHEMBL2094135 PhosphoSite:Q96BI3 DMDM:37077707 PaxDb:Q96BI3 PRIDE:Q96BI3 DNASU:51107 Ensembl:ENST00000360244 Ensembl:ENST00000369109 Ensembl:ENST00000414276 Ensembl:ENST00000581822 Ensembl:ENST00000582205 Ensembl:ENST00000584744 GeneID:51107 KEGG:hsa:51107 UCSC:uc001ety.2 UCSC:uc001etz.2 UCSC:uc010pbx.2 CTD:51107 GeneCards:GC01M150237 HGNC:HGNC:29509 HPA:CAB037272 MIM:607629 neXtProt:NX_Q96BI3 PharmGKB:PA142672599 eggNOG:NOG300477 HOGENOM:HOG000007541 HOVERGEN:HBG050541 InParanoid:Q96BI3 KO:K06172 OMA:FIAFGPP PhylomeDB:Q96BI3 TreeFam:TF314362 SignaLink:Q96BI3 GenomeRNAi:51107 NextBio:53845 PRO:PR:Q96BI3 ArrayExpress:Q96BI3 Bgee:Q96BI3 CleanEx:HS_APH1A Genevestigator:Q96BI3 GO:GO:0001656 PANTHER:PTHR12889 Uniprot:Q96BI3)

HSP 1 Score: 144.436 bits (363), Expect = 8.637e-40
Identity = 87/211 (41.23%), Postives = 123/211 (58.29%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEP---------VFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKP---HILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGI 199
            M A  F+G    AFG   A+F+ T+A DP+R+I+LV  +FFWL+S L++S+ WF +V +             +FG   SV  QE+FR   Y LL KA   ++ L+E+    G  P     +AYV G  FGI SG+F ++N+LAD+LGPG +GI G     S ++F+ SA  + AI+L HT WGV+ F ACE ++Y  L  V   H   SG+
Sbjct:    1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVTDRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSED----GRSPISIRQMAYVSGLSFGIISGVFSVINILADALGPGVVGIHGD----SPYYFLTSAFLTAAIILLHTFWGVVFFDACERRRYWALGLVVGSHLLTSGL 203          

BLAST of EMLSAG00000000913 vs. GO
Match: - (symbol:APH1 "Anterior pharynx defective 1 homolog A" species:9615 "Canis lupus familiaris" [GO:0001656 "metanephros development" evidence=IEA] [GO:0004175 "endopeptidase activity" evidence=IEA] [GO:0005783 "endoplasmic reticulum" evidence=IEA] [GO:0005794 "Golgi apparatus" evidence=IEA] [GO:0005887 "integral component of plasma membrane" evidence=IEA] [GO:0006509 "membrane protein ectodomain proteolysis" evidence=IEA] [GO:0007220 "Notch receptor processing" evidence=IEA] [GO:0031293 "membrane protein intracellular domain proteolysis" evidence=IEA] [GO:0042987 "amyloid precursor protein catabolic process" evidence=IEA] [GO:0043085 "positive regulation of catalytic activity" evidence=IEA] InterPro:IPR009294 Pfam:PF06105 GO:GO:0005783 GO:GO:0005794 GO:GO:0043085 GO:GO:0005887 GO:GO:0042987 GO:GO:0004175 GO:GO:0006509 GO:GO:0007220 GO:GO:0031293 GO:GO:0016485 KO:K06172 OMA:FIAFGPP TreeFam:TF314362 GO:GO:0001656 PANTHER:PTHR12889 GeneTree:ENSGT00390000002049 OrthoDB:EOG7TF7B1 EMBL:AAEX03011047 EMBL:AB793323 RefSeq:XP_003639673.1 Ensembl:ENSCAFT00000018712 GeneID:100855839 KEGG:cfa:100855839 CTD:100855839 NextBio:20857618 Uniprot:E2R5H5)

HSP 1 Score: 144.436 bits (363), Expect = 9.594e-40
Identity = 87/211 (41.23%), Postives = 123/211 (58.29%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEP---------VFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKP---HILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGI 199
            M A  F+G    AFG   A+F+ T+A DP+R+I+LV  +FFWL+S L++S+ WF +V +             +FG   SV  QE+FR   Y LL KA   ++ L+E+    G  P     +AYV G  FGI SG+F ++N+LAD+LGPG +GI G     S ++F+ SA  + AI+L HT WGV+ F ACE ++Y  L  V   H   SG+
Sbjct:    1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVTDRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSED----GRSPISIRQMAYVSGLSFGIISGVFSVINILADALGPGVVGIHGD----SPYYFLTSAFLTAAIILLHTFWGVVFFDACERRRYWALGLVVGSHLLTSGL 203          

BLAST of EMLSAG00000000913 vs. GO
Match: - (symbol:Aph1a "anterior pharynx defective 1a homolog (C. elegans)" species:10090 "Mus musculus" [GO:0001656 "metanephros development" evidence=IMP] [GO:0004175 "endopeptidase activity" evidence=IDA;IMP] [GO:0005515 "protein binding" evidence=IPI] [GO:0005783 "endoplasmic reticulum" evidence=ISO] [GO:0005794 "Golgi apparatus" evidence=ISO] [GO:0005887 "integral component of plasma membrane" evidence=ISO] [GO:0006508 "proteolysis" evidence=IMP] [GO:0006509 "membrane protein ectodomain proteolysis" evidence=ISO] [GO:0007219 "Notch signaling pathway" evidence=IEA] [GO:0007220 "Notch receptor processing" evidence=ISO;IMP] [GO:0008233 "peptidase activity" evidence=ISA] [GO:0016020 "membrane" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=ISA] [GO:0016485 "protein processing" evidence=ISO;ISA] [GO:0031293 "membrane protein intracellular domain proteolysis" evidence=ISO] [GO:0042987 "amyloid precursor protein catabolic process" evidence=ISO] [GO:0043085 "positive regulation of catalytic activity" evidence=ISO] Reactome:REACT_99294 InterPro:IPR009294 Pfam:PF06105 MGI:MGI:2385110 GO:GO:0005783 GO:GO:0005794 GO:GO:0043085 GO:GO:0005887 GO:GO:0005789 GO:GO:0007219 Reactome:REACT_188257 GO:GO:0042987 GO:GO:0004175 GO:GO:0006509 GO:GO:0007220 Reactome:REACT_189085 GO:GO:0031293 GO:GO:0016485 CTD:51107 eggNOG:NOG300477 HOGENOM:HOG000007541 HOVERGEN:HBG050541 KO:K06172 OMA:FIAFGPP TreeFam:TF314362 GO:GO:0001656 PANTHER:PTHR12889 EMBL:BC012406 EMBL:BC024111 EMBL:AK078343 RefSeq:NP_666216.1 RefSeq:NP_666246.1 UniGene:Mm.306954 UniGene:Mm.337825 UniGene:Mm.486756 ProteinModelPortal:Q8BVF7 BioGrid:230528 MINT:MINT-1176936 STRING:10090.ENSMUSP00000048622 BindingDB:Q8BVF7 TCDB:9.B.47.1.1 PRIDE:Q8BVF7 Ensembl:ENSMUST00000015894 Ensembl:ENSMUST00000056710 GeneID:226548 KEGG:mmu:226548 UCSC:uc008qlq.1 GeneTree:ENSGT00390000002049 InParanoid:Q8BVF7 OrthoDB:EOG7TF7B1 NextBio:378222 PRO:PR:Q8BVF7 ArrayExpress:Q8BVF7 Bgee:Q8BVF7 Genevestigator:Q8BVF7 Uniprot:Q8BVF7)

HSP 1 Score: 144.05 bits (362), Expect = 1.235e-39
Identity = 95/266 (35.71%), Postives = 147/266 (55.26%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEP---------VFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKP---HILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGIVITSKPITTLRTYFDHDVLNSNVIDCH-GI--FHRRXGSVNSLKACFALRNGDSS 251
            M A  F+G    AFG   ++F+ T+A DP+R+I+LV  +FFWL+S L++S+ WF +V +             +FG   SV  QE+FR   Y LL KA   ++ L+E+    G  P     +AYV G  FGI SG+F ++N+LAD+LGPG +GI G     S ++F+ SA  + AI+L HT WGV+ F ACE ++Y      WA+   +   ++TS  +T L  +++  +L    +    G+  F    GS+ S++   + R  + S
Sbjct:    1 MGAAVFFGCTFVAFGPAFSLFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVTDRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSED----GRSPISIRQMAYVSGLSFGIISGVFSVINILADALGPGVVGIHGD----SPYYFLTSAFLTAAIILLHTFWGVVFFDACERRRY------WALGLVVGSHLLTSG-LTFLNPWYEASLLPIYAVTVSMGLWAFITAGGSLRSIQRSLSCRRQEDS 251          

BLAST of EMLSAG00000000913 vs. GO
Match: - (symbol:APH1A "Uncharacterized protein" species:9823 "Sus scrofa" [GO:0001656 "metanephros development" evidence=IEA] [GO:0004175 "endopeptidase activity" evidence=IEA] [GO:0005783 "endoplasmic reticulum" evidence=IEA] [GO:0005794 "Golgi apparatus" evidence=IEA] [GO:0005887 "integral component of plasma membrane" evidence=IEA] [GO:0006509 "membrane protein ectodomain proteolysis" evidence=IEA] [GO:0007220 "Notch receptor processing" evidence=IEA] [GO:0031293 "membrane protein intracellular domain proteolysis" evidence=IEA] [GO:0042987 "amyloid precursor protein catabolic process" evidence=IEA] [GO:0043085 "positive regulation of catalytic activity" evidence=IEA] InterPro:IPR009294 Pfam:PF06105 GO:GO:0005783 GO:GO:0005794 GO:GO:0043085 GO:GO:0005887 GO:GO:0042987 GO:GO:0004175 GO:GO:0006509 GO:GO:0007220 GO:GO:0031293 GO:GO:0016485 TreeFam:TF314362 GO:GO:0001656 PANTHER:PTHR12889 GeneTree:ENSGT00390000002049 OrthoDB:EOG7TF7B1 Ensembl:ENSSSCT00000023376 OMA:ACEKRRY Uniprot:I3L8R2)

HSP 1 Score: 140.198 bits (352), Expect = 2.232e-38
Identity = 85/211 (40.28%), Postives = 121/211 (57.35%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEP---------VFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKP---HILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGI 199
            M A  F+G     FG    +F+ T+A DP+R+I+LV  +FFWL+S L++S+ WF +V +             +FG   SV  QE+FR   Y LL KA   ++ L+E+    G  P     +AYV G  FGI SG+F ++N+LAD+LGPG +GI G     S ++F+ SA  + AI+L HT WGV+ F ACE ++Y  L  V   H   SG+
Sbjct:    1 MGAAVFFGCTFVXFGPAFRLFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVTDRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSED----GRSPISIRQMAYVSGLSFGIISGVFSVINILADALGPGVVGIHGD----SPYYFLTSAFLTAAIILLHTFWGVVFFDACERRRYWALGLVVGSHLLTSGL 203          

BLAST of EMLSAG00000000913 vs. GO
Match: - (symbol:APH1A "Uncharacterized protein" species:9031 "Gallus gallus" [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0016485 "protein processing" evidence=IEA] [GO:0043085 "positive regulation of catalytic activity" evidence=IEA] InterPro:IPR009294 Pfam:PF06105 GO:GO:0016021 GO:GO:0043085 GO:GO:0016485 CTD:51107 KO:K06172 TreeFam:TF314362 PANTHER:PTHR12889 GeneTree:ENSGT00390000002049 OrthoDB:EOG7TF7B1 EMBL:AC189009 RefSeq:XP_001233302.1 Ensembl:ENSGALT00000004064 GeneID:769986 KEGG:gga:769986 PRO:PR:E1C2N9 Uniprot:E1C2N9)

HSP 1 Score: 140.198 bits (352), Expect = 2.880e-38
Identity = 91/210 (43.33%), Postives = 128/210 (60.95%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPL---RHEP------VFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKP---HILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSG 198
            MT   F+G    AFG   ++F+FTIA DP+RII+L+  +FFWL+S L+SSL WF  V       EP      +FG++FSV  QE FR L Y LL KA   +  L+E+    G  P     +AYV G GFG+ SG F ++N+LAD+LGPGT+GI G     S+ +F+ SA  ++ ++  HT WG++ F  CE +++  +V V  MH A+SG
Sbjct:    1 MTLAVFFGCTFIAFGPAFSLFLFTIARDPLRIIILIAGAFFWLVSLLLSSLIWFIAVKASDPHDEPLQKGLLIFGVMFSVLLQEAFRFLYYKLLRKAIEGLVALSED----GCSPISIQQMAYVAGVGFGLMSGAFSMINLLADALGPGTVGIHGD----SQLYFLTSAFMTMVLIFLHTFWGILFFHGCENRRWWEIVAVVVMHLAVSG 202          

BLAST of EMLSAG00000000913 vs. GO
Match: - (symbol:zgc:114200 "zgc:114200" species:7955 "Danio rerio" [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0016485 "protein processing" evidence=IEA] [GO:0043085 "positive regulation of catalytic activity" evidence=IEA] InterPro:IPR009294 Pfam:PF06105 ZFIN:ZDB-GENE-050913-96 GO:GO:0016021 GO:GO:0043085 GO:GO:0016485 eggNOG:NOG300477 HOGENOM:HOG000007541 HOVERGEN:HBG050541 KO:K06172 PANTHER:PTHR12889 EMBL:BC097248 RefSeq:NP_001025300.1 UniGene:Dr.15922 STRING:7955.ENSDARP00000069056 GeneID:559336 KEGG:dre:559336 NextBio:20882911 Uniprot:Q4V8Q7)

HSP 1 Score: 126.716 bits (317), Expect = 3.427e-33
Identity = 85/208 (40.87%), Postives = 127/208 (61.06%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEP---------VFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGI 199
            MT   F+G    AFG   A+F+FT+A DP+R+I+L+  +FFWL+S L+SSL WF  V   +           +FG+ FSV  QE+FR   Y LL KA   ++ +++ D         +AYV G GFG+  G F ++N+L+DSLGPGT+GI    FG S+++FI +AL +LA+ L HT WGV+ F  CE+  +  +  V ++H  ++G+
Sbjct:    1 MTLAVFFGCAFIAFGPAFALFVFTVAKDPLRVIILIAGAFFWLLSLLLSSLVWFIAVKASNSQDPSLPRGLLIFGVFFSVLLQEVFRFAYYRLLRKATEGLAAISD-DASSAISVRQMAYVAGLGFGVMRGAFSMINILSDSLGPGTVGI----FGDSQYYFITAALMTLALTLLHTFWGVLFFEGCEKSSWWVIAVVVSLHLLVAGL 203          

BLAST of EMLSAG00000000913 vs. GO
Match: - (symbol:APH1B "Gamma-secretase subunit APH-1B" species:9606 "Homo sapiens" [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0016485 "protein processing" evidence=IEA] [GO:0043085 "positive regulation of catalytic activity" evidence=IEA] InterPro:IPR009294 Pfam:PF06105 GO:GO:0016021 GO:GO:0043085 GO:GO:0016485 PANTHER:PTHR12889 EMBL:AC016207 HGNC:HGNC:24080 ProteinModelPortal:H0YLT0 Ensembl:ENST00000560353 NextBio:35524533 ArrayExpress:H0YLT0 Bgee:H0YLT0 Uniprot:H0YLT0)

HSP 1 Score: 117.857 bits (294), Expect = 3.767e-30
Identity = 74/167 (44.31%), Postives = 97/167 (58.08%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWF---AVVPLRHEP------VFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSAL 158
            MTA  F+G    AFG   A+++FTIA +P+RII L+  +FFWL+S LISSL WF    ++  +  P      +FG   SV  QE+FR   Y LL KA   +  +   +        +LAYV G GFGI SG+F  VN L+DSLGPGT+GI G     S  FF++S L
Sbjct:    1 MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVIIDNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGET--APSMRLLAYVSGLGFGIMSGVFSFVNTLSDSLGPGTVGIHGD----SPQFFLYSDL 161          

BLAST of EMLSAG00000000913 vs. C. finmarchicus
Match: gi|592767245|gb|GAXK01187323.1| (TSA: Calanus finmarchicus comp11439_c0_seq2 transcribed RNA sequence)

HSP 1 Score: 147.902 bits (372), Expect = 4.987e-41
Identity = 108/185 (58.38%), Postives = 139/185 (75.14%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRXXXXXXXXXXXXXXXXXXXXXXXAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDP--IFGDKPHILAYVXXXXXXXXXXXXXXVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKY 183
            MTA+TF+G  LTA+G P A+F+ TI+ DPV+II+L+LS+FFWL+S L+S++ W AVVPL+ E  FGLVFSV FQE+FR L+YLLL KA +++ KLTE +   IF +K HILAYV+G GFG+ SG F LVNVLA SLGPGTLG  G       +FFI SA+ +L +VL HT+WGVI FS+ +   Y
Sbjct:   40 MTAYTFFGCALTAYGTPLALFLLTISSDPVKIIILILSAFFWLLSLLLSAILWTAVVPLKEELAFGLVFSVLFQELFRFLIYLLLDKADTYLKKLTETEETQIFANK-HILAYVVGLGFGLMSGAFSLVNVLAASLGPGTLGFNGEP----HNFFIVSAVMTLCMVLLHTSWGVIFFSSLDTGTY 579          

BLAST of EMLSAG00000000913 vs. C. finmarchicus
Match: gi|592767246|gb|GAXK01187322.1| (TSA: Calanus finmarchicus comp11439_c0_seq1 transcribed RNA sequence)

HSP 1 Score: 147.902 bits (372), Expect = 5.814e-41
Identity = 108/185 (58.38%), Postives = 139/185 (75.14%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRXXXXXXXXXXXXXXXXXXXXXXXAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDP--IFGDKPHILAYVXXXXXXXXXXXXXXVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKY 183
            MTA+TF+G  LTA+G P A+F+ TI+ DPV+II+L+LS+FFWL+S L+S++ W AVVPL+ E  FGLVFSV FQE+FR L+YLLL KA +++ KLTE +   IF +K HILAYV+G GFG+ SG F LVNVLA SLGPGTLG  G       +FFI SA+ +L +VL HT+WGVI FS+ +   Y
Sbjct:   40 MTAYTFFGCALTAYGTPLALFLLTISSDPVKIIILILSAFFWLLSLLLSAILWTAVVPLKEELAFGLVFSVLFQELFRFLIYLLLDKADTYLKKLTETEETQIFANK-HILAYVVGLGFGLMSGAFSLVNVLAASLGPGTLGFNGEP----HNFFIVSAVMTLCMVLLHTSWGVIFFSSLDTGTY 579          

BLAST of EMLSAG00000000913 vs. C. finmarchicus
Match: gi|592767241|gb|GAXK01187327.1| (TSA: Calanus finmarchicus comp11439_c0_seq6 transcribed RNA sequence)

HSP 1 Score: 73.559 bits (179), Expect = 1.810e-14
Identity = 53/99 (53.54%), Postives = 68/99 (68.69%), Query Frame = 0

Query:   87 KARSFMSKLTENDP--IFGDKPHILAYVXXXXXXXXXXXXXXVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKY 183
            +A +++ KLTE +   IF +K HILAYV+G GFG+ SG F LVNVLA SLGPGTLG  G       +FFI SA+ +L +VL HT+WGVI FS+ +   Y
Sbjct:  219 QADTYLKKLTETEETQIFANK-HILAYVVGLGFGLMSGAFSLVNVLAASLGPGTLGFNGEP----HNFFIVSAVMTLCMVLLHTSWGVIFFSSLDTGTY 500          

BLAST of EMLSAG00000000913 vs. C. finmarchicus
Match: gi|592767243|gb|GAXK01187325.1| (TSA: Calanus finmarchicus comp11439_c0_seq4 transcribed RNA sequence)

HSP 1 Score: 73.559 bits (179), Expect = 1.818e-14
Identity = 53/99 (53.54%), Postives = 68/99 (68.69%), Query Frame = 0

Query:   87 KARSFMSKLTENDP--IFGDKPHILAYVXXXXXXXXXXXXXXVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKY 183
            +A +++ KLTE +   IF +K HILAYV+G GFG+ SG F LVNVLA SLGPGTLG  G       +FFI SA+ +L +VL HT+WGVI FS+ +   Y
Sbjct:  219 QADTYLKKLTETEETQIFANK-HILAYVVGLGFGLMSGAFSLVNVLAASLGPGTLGFNGEP----HNFFIVSAVMTLCMVLLHTSWGVIFFSSLDTGTY 500          

BLAST of EMLSAG00000000913 vs. C. finmarchicus
Match: gi|592767242|gb|GAXK01187326.1| (TSA: Calanus finmarchicus comp11439_c0_seq5 transcribed RNA sequence)

HSP 1 Score: 73.559 bits (179), Expect = 1.900e-14
Identity = 53/99 (53.54%), Postives = 68/99 (68.69%), Query Frame = 0

Query:   87 KARSFMSKLTENDP--IFGDKPHILAYVXXXXXXXXXXXXXXVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKY 183
            +A +++ KLTE +   IF +K HILAYV+G GFG+ SG F LVNVLA SLGPGTLG  G       +FFI SA+ +L +VL HT+WGVI FS+ +   Y
Sbjct:  232 QADTYLKKLTETEETQIFANK-HILAYVVGLGFGLMSGAFSLVNVLAASLGPGTLGFNGEP----HNFFIVSAVMTLCMVLLHTSWGVIFFSSLDTGTY 513          

BLAST of EMLSAG00000000913 vs. C. finmarchicus
Match: gi|592767244|gb|GAXK01187324.1| (TSA: Calanus finmarchicus comp11439_c0_seq3 transcribed RNA sequence)

HSP 1 Score: 73.559 bits (179), Expect = 1.906e-14
Identity = 53/99 (53.54%), Postives = 68/99 (68.69%), Query Frame = 0

Query:   87 KARSFMSKLTENDP--IFGDKPHILAYVXXXXXXXXXXXXXXVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKY 183
            +A +++ KLTE +   IF +K HILAYV+G GFG+ SG F LVNVLA SLGPGTLG  G       +FFI SA+ +L +VL HT+WGVI FS+ +   Y
Sbjct:  232 QADTYLKKLTETEETQIFANK-HILAYVVGLGFGLMSGAFSLVNVLAASLGPGTLGFNGEP----HNFFIVSAVMTLCMVLLHTSWGVIFFSSLDTGTY 513          

BLAST of EMLSAG00000000913 vs. L. salmonis peptides
Match: EMLSAP00000000913 (pep:novel supercontig:LSalAtl2s:LSalAtl2s115:30103:30983:-1 gene:EMLSAG00000000913 transcript:EMLSAT00000000913 description:"maker-LSalAtl2s115-augustus-gene-0.5")

HSP 1 Score: 509.99 bits (1312), Expect = 0.000e+0
Identity = 257/257 (100.00%), Postives = 257/257 (100.00%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGIVITSKPITTLRTYFDHDVLNSNVIDCHGIFHRRXGSVNSLKACFALRNGDSSTNVFVR 257
            MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGIVITSKPITTLRTYFDHDVLNSNVIDCHGIFHRRXGSVNSLKACFALRNGDSSTNVFVR
Sbjct:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGIVITSKPITTLRTYFDHDVLNSNVIDCHGIFHRRXGSVNSLKACFALRNGDSSTNVFVR 257          

BLAST of EMLSAG00000000913 vs. SwissProt
Match: gi|37077998|sp|Q9VQG2.1|APH1_DROME (RecName: Full=Gamma-secretase subunit Aph-1; AltName: Full=Presenilin-stabilization factor)

HSP 1 Score: 158.303 bits (399), Expect = 1.150e-46
Identity = 94/186 (50.54%), Postives = 126/186 (67.74%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRL 186
            MT   F+G    AFG P A+F+FTIA DPVRII+L+ ++FFWL+S LISSLW+ A++PL+    FG+VFSV FQE FR ++Y +L      +  + E+  +  D  HILAYV G GFGI SG+F LVNVLAD  GPGT+G+KGG    +  FF+ SA  +L+I+L HT W VI F+A +   Y+ +
Sbjct:    1 MTLPEFFGCTFIAFGPPFALFVFTIANDPVRIIILIAAAFFWLLSLLISSLWY-ALIPLKEFLAFGVVFSVCFQEAFRYIIYRILRSTEQGLHAVAEDTRV-TDNKHILAYVSGLGFGIISGMFALVNVLADMSGPGTMGLKGG----TELFFVTSAAQALSIILLHTFWSVIFFNAFDTNNYIHI 180          

BLAST of EMLSAG00000000913 vs. SwissProt
Match: gi|37077156|sp|Q8C7N7.1|APH1B_MOUSE (RecName: Full=Gamma-secretase subunit APH-1B; Short=APH-1b; AltName: Full=Aph-1beta)

HSP 1 Score: 153.295 bits (386), Expect = 2.127e-44
Identity = 98/261 (37.55%), Postives = 142/261 (54.41%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPL---RHEPV------FGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGIVITSKPITTLRTYFDHDVLNSNVIDC-HGI--FHRRXGSVNSLKACFALRNGD 249
            MTA  F+G    AFG   A+++FTIA DP+R+I L+  +FFWL+S L+SS++WF V  +   R  PV      FG++ SV  QE+FR+  Y LL KA   +  +   +        +LAYV G GFGI SG+F  VN L++SLGPGT+GI G     S  FF+ SA  +L +++ H  WGV+ F  CE+ K       W     +    +     T L  Y++ +++ + +I    GI  F+   GS  SLK C   ++ D
Sbjct:    1 MTAAVFFGCAFIAFGPALALYVFTIATDPLRVIFLIAGAFFWLVSLLLSSVFWFLVRVITDNRDGPVQNYLLIFGVLLSVCIQELFRLAYYKLLKKASEGLKSINPEET--APSMRLLAYVSGLGFGIMSGVFSFVNTLSNSLGPGTVGIHGD----SPQFFLNSAFMTLVVIMLHVFWGVVFFDGCEKNK-------WYTLLTVLLTHLVVSTQTFLSPYYEVNLVTAYIIMVLMGIWAFYVAGGSCRSLKLCLLCQDKD 248          

BLAST of EMLSAG00000000913 vs. SwissProt
Match: gi|37077773|sp|Q9DCZ9.1|APH1C_MOUSE (RecName: Full=Putative gamma-secretase subunit APH-1C)

HSP 1 Score: 150.599 bits (379), Expect = 2.040e-43
Identity = 98/261 (37.55%), Postives = 141/261 (54.02%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPL---RHEPV------FGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGIVITSKPITTLRTYFDHDVLNSNVIDC-HGI--FHRRXGSVNSLKACFALRNGD 249
            MT   F+G    AFG   A+++FTIA DP+R+I L+  +FFWL+S L+SS++WF V  +   R E V      FG + SV  QE+FR+  Y LL KA   +  +   + I      +LAYV G GFGI SG+F  VN L++SLGPGT+GI G     S  FF+ SA  +L +++ H  WGV+ F  CE+ K       W     +    +     T L  Y++ +++ + +I    GI  F+   GS  SLK C   ++ D
Sbjct:    1 MTLPVFFGCAFIAFGPAFALYLFTIATDPLRVIFLIAGAFFWLVSLLLSSMFWFLVRVITNNRDESVQNYLLIFGALLSVCIQELFRLAYYKLLKKASEGLKSINPEEDI-APSMRLLAYVSGLGFGIMSGVFSFVNTLSNSLGPGTVGIHGD----SPQFFLNSAFMTLVVIMLHVFWGVVFFDGCEKNK-------WYTLLTVLLTHLVVSTQTFLSPYYEVNLVTAYIIMVLMGIWAFYVAGGSCRSLKFCLLCQDKD 249          

BLAST of EMLSAG00000000913 vs. SwissProt
Match: gi|37077309|sp|Q8JHE9.1|APH1B_DANRE (RecName: Full=Gamma-secretase subunit Aph-1b; AltName: Full=Anterior-pharynx-defective protein 1b)

HSP 1 Score: 150.599 bits (379), Expect = 2.583e-43
Identity = 106/262 (40.46%), Postives = 146/262 (55.73%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEP---------VFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTEND--PIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGIVITSKPI--TTLRTYFDHDVLNSNVIDCHGIFHRRXGSVNSLKACFALRNGD 249
            MT   F+G    AFG   A+F+FTIA DP+R+I L+  +FFWL+S L+SSL WF  V + ++          +FG+V SV  QE FR   Y LL KA   +  L++ D  PI   +   LAYV G GFG  SG F +VN+L+DSLGPGT+GI G     S+H+FI SA  +LAI+L H  WGV+ F ACE +++  L  V A H  +S +   +     + + TY    V+      C G      GS+ +LK C   ++ D
Sbjct:    1 MTVAVFFGCTFIAFGPAIALFMFTIARDPLRVIFLIAGAFFWLVSLLLSSLVWFITVQISNKNSATQQRGLLIFGVVLSVLLQEAFRYGYYRLLKKANEGLLALSQEDTMPISMRQ---LAYVSGLGFGFMSGAFSVVNILSDSLGPGTVGIHGE----SQHYFISSAFMTLAIILLHMFWGVVFFEACERQRWWALGAVVASHLVVSCLTFVNPHYQGSLIPTYIILSVMAVWAYLCAG------GSLRNLKLCLTCKDKD 249          

BLAST of EMLSAG00000000913 vs. SwissProt
Match: gi|71152230|sp|Q5RDM3.1|APH1B_PONAB (RecName: Full=Gamma-secretase subunit APH-1B; Short=APH-1b; AltName: Full=Aph-1beta)

HSP 1 Score: 149.058 bits (375), Expect = 7.279e-43
Identity = 97/261 (37.16%), Postives = 138/261 (52.87%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWF---AVVPLRHEP------VFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGIVITSKPITTLRTYFDHDVLNSNVIDC---HGIFHRRXGSVNSLKACFALRNGD 249
            MTA  F+G    AFG   A+++FTIA +P+RII L+  +FFWL+S LISSL WF    ++  +  P      +FG   SV  QE+FR   Y LL KA   +  +   +        +LAYV G GFGI SG+F  VN L+DSLGPGT+GI G     S  FF++SA  +L I+L H  WG++ F  CE+KK       W +   +    +     T + +Y+  ++ ++ +I        F    GS  SLK C   ++ D
Sbjct:    1 MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVIIDNKDGPTQKYLLIFGTFVSVYIQEMFRFAYYRLLKKASEGLKSINPGET--APSMRLLAYVSGLGFGIMSGVFSFVNTLSDSLGPGTVGIHGD----SPQFFLYSAFMTLVIILLHVFWGIVFFDGCEKKK-------WGILLIVLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLKLCLLCQDKD 248          

BLAST of EMLSAG00000000913 vs. SwissProt
Match: gi|61252592|sp|Q8WW43.3|APH1B_HUMAN (RecName: Full=Gamma-secretase subunit APH-1B; Short=APH-1b; AltName: Full=Aph-1beta; AltName: Full=Presenilin-stabilization factor-like)

HSP 1 Score: 147.517 bits (371), Expect = 3.600e-42
Identity = 96/261 (36.78%), Postives = 138/261 (52.87%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWF---AVVPLRHEP------VFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGIVITSKPITTLRTYFDHDVLNSNVIDC---HGIFHRRXGSVNSLKACFALRNGD 249
            MTA  F+G    AFG   A+++FTIA +P+RII L+  +FFWL+S LISSL WF    ++  +  P      +FG   SV  QE+FR   Y LL KA   +  +   +        +LAYV G GFGI SG+F  VN L+DSLGPGT+GI G     S  FF++SA  +L I+L H  WG++ F  CE+KK       W +   +    +     T + +Y+  ++ ++ +I        F    GS  SLK C   ++ +
Sbjct:    1 MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVIIDNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGET--APSMRLLAYVSGLGFGIMSGVFSFVNTLSDSLGPGTVGIHGD----SPQFFLYSAFMTLVIILLHVFWGIVFFDGCEKKK-------WGILLIVLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLKLCLLCQDKN 248          

BLAST of EMLSAG00000000913 vs. SwissProt
Match: gi|37077707|sp|Q96BI3.1|APH1A_HUMAN (RecName: Full=Gamma-secretase subunit APH-1A; Short=APH-1a; AltName: Full=Aph-1alpha; AltName: Full=Presenilin-stabilization factor)

HSP 1 Score: 144.436 bits (363), Expect = 5.749e-41
Identity = 87/211 (41.23%), Postives = 123/211 (58.29%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEP---------VFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKP---HILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGI 199
            M A  F+G    AFG   A+F+ T+A DP+R+I+LV  +FFWL+S L++S+ WF +V +             +FG   SV  QE+FR   Y LL KA   ++ L+E+    G  P     +AYV G  FGI SG+F ++N+LAD+LGPG +GI G     S ++F+ SA  + AI+L HT WGV+ F ACE ++Y  L  V   H   SG+
Sbjct:    1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVTDRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSED----GRSPISIRQMAYVSGLSFGIISGVFSVINILADALGPGVVGIHGD----SPYYFLTSAFLTAAIILLHTFWGVVFFDACERRRYWALGLVVGSHLLTSGL 203          

BLAST of EMLSAG00000000913 vs. SwissProt
Match: gi|37077149|sp|Q8BVF7.2|APH1A_MOUSE (RecName: Full=Gamma-secretase subunit APH-1A; Short=APH-1a; AltName: Full=Aph-1alpha)

HSP 1 Score: 144.05 bits (362), Expect = 8.272e-41
Identity = 95/266 (35.71%), Postives = 147/266 (55.26%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEP---------VFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKP---HILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGIVITSKPITTLRTYFDHDVLNSNVIDCH-GI--FHRRXGSVNSLKACFALRNGDSS 251
            M A  F+G    AFG   ++F+ T+A DP+R+I+LV  +FFWL+S L++S+ WF +V +             +FG   SV  QE+FR   Y LL KA   ++ L+E+    G  P     +AYV G  FGI SG+F ++N+LAD+LGPG +GI G     S ++F+ SA  + AI+L HT WGV+ F ACE ++Y      WA+   +   ++TS  +T L  +++  +L    +    G+  F    GS+ S++   + R  + S
Sbjct:    1 MGAAVFFGCTFVAFGPAFSLFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVTDRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSED----GRSPISIRQMAYVSGLSFGIISGVFSVINILADALGPGVVGIHGD----SPYYFLTSAFLTAAIILLHTFWGVVFFDACERRRY------WALGLVVGSHLLTSG-LTFLNPWYEASLLPIYAVTVSMGLWAFITAGGSLRSIQRSLSCRRQEDS 251          

BLAST of EMLSAG00000000913 vs. SwissProt
Match: gi|37076812|sp|O45876.1|APH1_CAEEL (RecName: Full=Gamma-secretase subunit aph-1; AltName: Full=Anterior-pharynx-defective protein 1; AltName: Full=Presenilin enhancer protein 1)

HSP 1 Score: 89.7373 bits (221), Expect = 6.846e-20
Identity = 60/187 (32.09%), Postives = 95/187 (50.80%), Query Frame = 0

Query:   10 FLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEP-VFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPI--------FGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLG----IKGGDFGVSRHFFIFSALFSLAIVLC---HTAWGVIAFSACEE 180
            ++ +F    A+F   IA DPVRIIL  L SFFWL+S L SSL W  +  +  +  +  L   +  QE+ R+  ++LL KA+  ++K+T    I          +  H+LA V G G G+ S LF  +N  A   GPGT+G    +K G+   +R        ++L+ +L    H  W ++ + +C +
Sbjct:   10 YIASFSPSIALFCSFIAHDPVRIILFFLGSFFWLVSLLFSSLAWLGLSTVLPDTFLLSLTVCIIAQELSRVAYFMLLKKAQRGLNKITRQGQISVAPGVSDLHNARHMLALVCGLGMGVISALFYTMNAFAIFSGPGTIGLPNALKTGEIDTNRAGKYLPLCYTLSAILLTLFHVTWTIMVWDSCHK 196          

BLAST of EMLSAG00000000913 vs. SwissProt
Match: gi|74859324|sp|Q55FS3.1|APH1_DICDI (RecName: Full=Gamma-secretase subunit Aph-1)

HSP 1 Score: 65.4698 bits (158), Expect = 3.426e-11
Identity = 38/102 (37.25%), Postives = 55/102 (53.92%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRIL---LYLLLFKARSFMSKLTEND 99
            MT   F+G     F    A F   IA +   +IL +  SFFWL+S LI+++WW+ + P+R    F + FSV FQEIFR +   LY   F  R  ++++ E  
Sbjct:    1 MTQVLFYGCLFITFSPILAFFFMVIAKNSQLVILTIGGSFFWLVSILIAAIWWYIIPPMREHWWFIISFSVLFQEIFRYIFFRLYSYGFNDRPSLNQIKETQ 102          

BLAST of EMLSAG00000000913 vs. Select Arthropod Genomes
Match: XP_006560654.1 (PREDICTED: gamma-secretase subunit Aph-1 [Apis mellifera])

HSP 1 Score: 169.859 bits (429), Expect = 2.355e-51
Identity = 103/216 (47.69%), Postives = 139/216 (64.35%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGI----VITSKPITTLRTY 212
            MT   F+G    AFG P AMF FT+A +P+RII+L+ S+FFWLIS L+SS+ W+AVVPL++   FGLVFSV FQE FR LLY +L KA   + K+T       D  H+ AYV G GFG  SG+F LVNVLAD++GPGT+G++ G    + +FF+ SA  +L  +L HT WGV+ FSA + K + +++ V   H  +S +    V  +   TTL  Y
Sbjct:    1 MTVMDFFGCAFLAFGPPLAMFTFTVAAEPIRIIILIASAFFWLISLLLSSILWYAVVPLQNHLAFGLVFSVLFQEAFRYLLYWVLRKAERGLDKVTTTH--VADSRHVFAYVCGLGFGFMSGVFALVNVLADAVGPGTMGLRQG----TEYFFVISAATTLCFILLHTFWGVVFFSALDRKNWGQVIWVVGSHLFVSCMTLLNVKEAYVATTLSAY 210          

BLAST of EMLSAG00000000913 vs. Select Arthropod Genomes
Match: EFX71350.1 (hypothetical protein DAPPUDRAFT_308872 [Daphnia pulex])

HSP 1 Score: 165.236 bits (417), Expect = 1.848e-49
Identity = 105/197 (53.30%), Postives = 129/197 (65.48%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALS 197
            M    F+G    AFG P AMF+ TIA DP+RII+L+ S+FFWL+S L SSL W   V L    V G++FSV FQE+FR L+YLLL KA   + KLTE+D       +ILAYV G GFGI SG F LVNVLAD+ GPGT+G+ G     S  FF+ SAL +L  +L HTAWGV+ F A ++KKYL LV V   H  +S
Sbjct:    1 MALLEFFGCAFLAFGPPLAMFLLTIAKDPIRIIILIASAFFWLLSLLTSSLLWLVAVTLHSPIVVGVIFSVLFQELFRYLIYLLLRKAEVGLKKLTESDTAIITNKNILAYVSGLGFGIISGTFSLVNVLADATGPGTVGLHGD----SNLFFLTSALLTLCFILLHTAWGVLFFHALDKKKYLALVWVVMSHLLVS 193          

BLAST of EMLSAG00000000913 vs. Select Arthropod Genomes
Match: gb|EFA04103.1| (Gamma-secretase subunit Aph-1-like Protein [Tribolium castaneum])

HSP 1 Score: 164.081 bits (414), Expect = 4.042e-49
Identity = 113/251 (45.02%), Postives = 150/251 (59.76%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGIVITS---KPITTLRTYFDHDVLNSNVIDCHGIFHRRX--GSVNSLKACFALR 246
            MT   F+G    AFG P AMF+FTIA DPVRII+L+ ++FFWL+S L+SSLWW+ VVPLR +  FG+VFSV FQE FR ++Y +L KA + + K+T++     +  HILAYV G GFGI SG F LVN+LAD++GPGT+G+KGG+      FF+ SA   L   L HT WGVI F+A +      +  V   H   S I + +    P  TL   + + VL        G+   R   GS  S K+C   +
Sbjct:    1 MTLVEFFGCTFLAFGPPFAMFVFTIAHDPVRIIILIAAAFFWLVSLLLSSLWWYIVVPLRQDLAFGVVFSVFFQETFRYIIYKILRKAENGLKKITDDSTQLIENKHILAYVSGLGFGIISGAFSLVNILADAVGPGTMGLKGGN----EMFFLTSAATGLCFTLLHTFWGVIFFNALDNSNKCYVGVVVVSHLLSSCITLLNFKVGPAGTLIPLYFNLVL-------MGLMAYRVAGGSYASFKSCITFK 240          

BLAST of EMLSAG00000000913 vs. Select Arthropod Genomes
Match: EAA14158.3 (AGAP009816-PA [Anopheles gambiae str. PEST])

HSP 1 Score: 162.54 bits (410), Expect = 1.465e-48
Identity = 94/193 (48.70%), Postives = 121/193 (62.69%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMH 193
            MT   F+G    AFG P AMF  TIA DP+RII+L+ +SFFWL+S L+SS  W A  P+  +  FGL+ SV  QE FR L+Y +L K  S + ++T+   I  D  HIL+Y  G GFGI SG F LVN+LADS+GP T+G+K      S  F + SA  SLA++L HT W VI F+AC+ K Y  +  V A H
Sbjct:    1 MTVVEFFGCSFLAFGPPVAMFALTIAHDPIRIIILIAASFFWLVSLLLSSTVWLAFHPVTSKVTFGLICSVFIQEGFRYLMYKVLRKTESGLQEVTDIVRI-ADYRHILSYASGLGFGIISGAFSLVNILADSVGPATVGLKAA----SDIFMLISAAQSLAMILLHTFWSVIFFNACDVKNYYHIGYVVASH 188          

BLAST of EMLSAG00000000913 vs. Select Arthropod Genomes
Match: AGB92500.1 (anterior pharynx defective 1, isoform B [Drosophila melanogaster])

HSP 1 Score: 158.303 bits (399), Expect = 5.573e-47
Identity = 94/186 (50.54%), Postives = 126/186 (67.74%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRL 186
            MT   F+G    AFG P A+F+FTIA DPVRII+L+ ++FFWL+S LISSLW+ A++PL+    FG+VFSV FQE FR ++Y +L      +  + E+  +  D  HILAYV G GFGI SG+F LVNVLAD  GPGT+G+KGG    +  FF+ SA  +L+I+L HT W VI F+A +   Y+ +
Sbjct:    1 MTLPEFFGCTFIAFGPPFALFVFTIANDPVRIIILIAAAFFWLLSLLISSLWY-ALIPLKEFLAFGVVFSVCFQEAFRYIIYRILRSTEQGLHAVAEDTRV-TDNKHILAYVSGLGFGIISGMFALVNVLADMSGPGTMGLKGG----TELFFVTSAAQALSIILLHTFWSVIFFNAFDTNNYIHI 180          

BLAST of EMLSAG00000000913 vs. Select Arthropod Genomes
Match: AAF51212.1 (anterior pharynx defective 1, isoform A [Drosophila melanogaster])

HSP 1 Score: 158.303 bits (399), Expect = 5.573e-47
Identity = 94/186 (50.54%), Postives = 126/186 (67.74%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRL 186
            MT   F+G    AFG P A+F+FTIA DPVRII+L+ ++FFWL+S LISSLW+ A++PL+    FG+VFSV FQE FR ++Y +L      +  + E+  +  D  HILAYV G GFGI SG+F LVNVLAD  GPGT+G+KGG    +  FF+ SA  +L+I+L HT W VI F+A +   Y+ +
Sbjct:    1 MTLPEFFGCTFIAFGPPFALFVFTIANDPVRIIILIAAAFFWLLSLLISSLWY-ALIPLKEFLAFGVVFSVCFQEAFRYIIYRILRSTEQGLHAVAEDTRV-TDNKHILAYVSGLGFGIISGMFALVNVLADMSGPGTMGLKGG----TELFFVTSAAQALSIILLHTFWSVIFFNAFDTNNYIHI 180          

BLAST of EMLSAG00000000913 vs. Select Arthropod Genomes
Match: gb|KFM64181.1| (Gamma-secretase subunit Aph-1, partial [Stegodyphus mimosarum])

HSP 1 Score: 158.303 bits (399), Expect = 7.947e-47
Identity = 105/254 (41.34%), Postives = 146/254 (57.48%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTE---NDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGIVITSKPITTLRTYFDHDVLNSNVIDCHGI--FHRRXGSVNSLKACFALRNGD 249
            MT   F+G  + AFG  +AM   TIA DP+RII+L+ ++FFWL+S L+SS+ W  VVPLR +  FG+VFSV FQEIFR   Y LL KA   + K+ E   +  +       LAYV G GFG+ SGLF L+NVLADS+GPGT+G+    +G S  FF+ SA  +LA  L HT WGV+ F A + + Y ++  V   H  +S + + ++     R Y    +    V    G+  +    GS  SL A  + +N +
Sbjct:    1 MTVMEFFGCAMIAFGPSAAMLAITIARDPIRIIILISAAFFWLLSLLLSSILWNVVVPLRKQLAFGVVFSVIFQEIFRFCFYKLLRKAEVGLKKVQEVGADGAVVSSNRSTLAYVAGLGFGLMSGLFSLINVLADSVGPGTVGL----YGDSHFFFLTSAFTTLAFTLLHTFWGVVFFHAWDNRSYGKITFVCLSHLLVSCMTLLNQQ----RLYVASFIPLYIVTITSGVLAYQSAGGSWKSLLASLSTKNSN 246          

BLAST of EMLSAG00000000913 vs. Select Arthropod Genomes
Match: EEB15054.1 (gamma-secretase subunit Aph-1, putative [Pediculus humanus corporis])

HSP 1 Score: 142.895 bits (359), Expect = 5.264e-41
Identity = 90/186 (48.39%), Postives = 124/186 (66.67%), Query Frame = 0

Query:   14 FGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGI 199
            FG P AMF+ TIA DP+RII+L+ S+FFWL+S L+SS   + ++P +H   +GL++SV FQE+FR ++Y L+  A   + K+T+N+    +  HILAYV G GFGI SGLF L+NVLADSLGP T+G+  G    S  FF+ SA  +L  +L HT WGVI FSA + K Y+ +  V   H  +S +
Sbjct:    7 FGPPLAMFVCTIALDPIRIIILIASAFFWLLSFLLSSFL-WFIIPGQHLS-YGLLYSVLFQELFRFIVYKLIRSAEGGLKKITDNETQIIENKHILAYVAGLGFGIMSGLFALINVLADSLGPATMGLHQG----SEKFFMTSAATTLCFILLHTFWGVIFFSAADSKNYINITWVLLTHLIVSAL 186          

BLAST of EMLSAG00000000913 vs. Select Arthropod Genomes
Match: gb|EEC01233.1| (anterior pharynx defective, putative [Ixodes scapularis])

HSP 1 Score: 142.51 bits (358), Expect = 1.414e-40
Identity = 96/204 (47.06%), Postives = 130/204 (63.73%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTE---NDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGIVI 201
            MT   F+G  L AFG   +MF  T+A DP+RII+L+ ++FFWL++ L+SS+ WFA VPLR E  FG+VFSV FQE FR L Y +L KA   + K+TE   +          L+YV G GFGI SG+F L+NVLAD+ GPGT+G+ GG    S +FF+ SAL + A VL HT WGV++F A +  ++  +  V A H   S + +
Sbjct:    1 MTLMEFFGCTLIAFGPALSMFAITVARDPIRIIILITAAFFWLLALLLSSILWFAAVPLRKELAFGVVFSVFFQEAFRYLFYKILRKAEVGLKKVTEVGADGASVSTSRTTLSYVAGLGFGIMSGVFSLLNVLADATGPGTVGLHGG----SPYFFVTSALTTQAFVLLHTFWGVVSFHALDHGRWPLVGFVLACHLTASTLTL 200          

BLAST of EMLSAG00000000913 vs. nr
Match: gi|290563082|gb|ADD38935.1| (Gamma-secretase subunit Aph-1 [Lepeophtheirus salmonis])

HSP 1 Score: 437.958 bits (1125), Expect = 4.004e-154
Identity = 228/261 (87.36%), Postives = 236/261 (90.42%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGIVITSK----PITTLRTYFDHDVLNSNVIDCHGIFHRRXGSVNSLKACFALRNGDSSTNVFVR 257
            MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLIS LISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGI + ++     +T + TY    +L S++      F    GSVNSLKACFALRNGDSSTNVFVR
Sbjct:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISLLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGISLLNQSQLYALTLITTYL---ILTSSIAMA---FFIAGGSVNSLKACFALRNGDSSTNVFVR 255          

BLAST of EMLSAG00000000913 vs. nr
Match: gi|290462079|gb|ADD24087.1| (Gamma-secretase subunit Aph-1 [Lepeophtheirus salmonis])

HSP 1 Score: 435.647 bits (1119), Expect = 2.945e-153
Identity = 227/261 (86.97%), Postives = 235/261 (90.04%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGIVITSK----PITTLRTYFDHDVLNSNVIDCHGIFHRRXGSVNSLKACFALRNGDSSTNVFVR 257
            MTAWTFWGT LTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLIS LISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGI + ++     +T + TY    +L S++      F    GSVNSLKACFALRNGDSSTNVFVR
Sbjct:    1 MTAWTFWGTLLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISLLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGISLLNQSQLYALTLITTYL---ILTSSIAMA---FFIAGGSVNSLKACFALRNGDSSTNVFVR 255          

BLAST of EMLSAG00000000913 vs. nr
Match: gi|225711918|gb|ACO11805.1| (Gamma-secretase subunit Aph-1 [Lepeophtheirus salmonis])

HSP 1 Score: 434.106 bits (1115), Expect = 1.412e-152
Identity = 226/261 (86.59%), Postives = 234/261 (89.66%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGIVITSK----PITTLRTYFDHDVLNSNVIDCHGIFHRRXGSVNSLKACFALRNGDSSTNVFVR 257
            MTAWTFWGT LTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLIS LISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSL IVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGI + ++     +T + TY    +L S++      F    GSVNSLKACFALRNGDSSTNVFVR
Sbjct:    1 MTAWTFWGTLLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISLLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLVIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGISLLNQSQLYALTLITTYL---ILTSSIAMA---FFIAGGSVNSLKACFALRNGDSSTNVFVR 255          

BLAST of EMLSAG00000000913 vs. nr
Match: gi|665819102|ref|XP_008558412.1| (PREDICTED: gamma-secretase subunit Aph-1 [Microplitis demolitor])

HSP 1 Score: 187.578 bits (475), Expect = 1.273e-55
Identity = 113/249 (45.38%), Postives = 148/249 (59.44%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGIVITSKPITTLRTYFDHDVLNSNVIDCHGIFHRRXGSVNSLKACFALRNGD 249
            MTA  F+G  L AFG P AMF  T++ +P+RII+L+ S+FFWLIS L SS+ W+AVVPL++   FGLVFSV FQE FR LLY +L KA   + K+T       +  HI AYV G GFG  SG F LVNVLAD++GPGT+G+K G    S +FFI SA  +L  +L HT WGVI FSA ++KK+  +  V   H   S + + ++      TY    V    +I     F    G + ++  CF L   D
Sbjct:    1 MTASDFFGCALLAFGPPLAMFTITVSSEPIRIIILIASAFFWLISLLFSSILWYAVVPLQNNLAFGLVFSVLFQEAFRYLLYWVLRKAEKGLEKVTTAH--LANSRHIFAYVCGLGFGFMSGAFALVNVLADAVGPGTMGLKQG----SEYFFIMSAATTLCFILLHTFWGVIFFSAADDKKWGHIAWVVLSHLFASCMTLINR--YEAYTYSLLSVYTVLIITMGLAFKVAGGKIQNIPKCFTLIKRD 241          

BLAST of EMLSAG00000000913 vs. nr
Match: gi|914574049|gb|KOB76437.1| (Anterior pharynx defective 1 [Operophtera brumata])

HSP 1 Score: 180.259 bits (456), Expect = 9.065e-53
Identity = 107/247 (43.32%), Postives = 149/247 (60.32%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGIVITSKPITTLRTYFDHDVLNSNVIDCHGIFHRRXGSVNSLKACFALRN 247
            MT   F+   L AFGAP AMF  TIA DPVRII++++++F WL++ L+SSL WFAVVPLR    FG+VF++ FQE FR  +YLLL K  + M +++EN  I  ++   +AYV G GFGI SG F L+NVLADS GPGTLG+K G    S  FF+ SA  +L ++L +T W VI +S  +EK  L++  V   H+ +S + + ++    + T     V+   VI     F    G+  S    F  R+
Sbjct:    1 MTLAEFFSCSLLAFGAPLAMFTMTIAHDPVRIIIMIVAAFGWLLAFLLSSLVWFAVVPLRSYLAFGMVFAIIFQEAFRYGMYLLLRKTEAGMKEISENHDIGSNRTE-MAYVSGLGFGIMSGAFALINVLADSAGPGTLGLKSG----SEFFFVTSAAMTLCMILLNTFWSVIFYSGIDEKNKLKIAWVIISHFVVSSLSLLNRKEIYMSTILPSYVI--LVITMLLAFRSAGGTAKSFIQSFTPRD 240          

BLAST of EMLSAG00000000913 vs. nr
Match: gi|913312794|ref|XP_013187142.1| (PREDICTED: gamma-secretase subunit Aph-1b [Amyelois transitella])

HSP 1 Score: 178.718 bits (452), Expect = 3.279e-52
Identity = 95/205 (46.34%), Postives = 136/205 (66.34%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGIVITSKP 205
            MT   F+   L A+GAP  MF  T+A DPVRII+++ ++F WL+S L+SS+ W+AVVPLR    FG+ F++ FQE+FR  +Y LL K  + + +++EN  I  +K   +AYV G GFG  SG F LVNVLADS+GPGTLG++ G    S +FF+ SA  +L ++L +T W VI FS C+EK Y ++  V   H+ +SGI + ++ 
Sbjct:    1 MTLAEFFSCSLLAYGAPFVMFSITVANDPVRIIIMIAAAFGWLLSFLLSSVVWYAVVPLRSYLAFGMTFAIIFQELFRYGMYRLLKKTEAGLKEISENHDIGANKLE-MAYVSGLGFGTMSGAFALVNVLADSIGPGTLGLQSG----SEYFFVTSAAMTLCMILLNTFWSVIFFSGCDEKNYFKVSWVLVSHFFVSGISLLNRK 200          

BLAST of EMLSAG00000000913 vs. nr
Match: gi|1000743321|ref|XP_015594338.1| (PREDICTED: gamma-secretase subunit Aph-1 [Cephus cinctus])

HSP 1 Score: 177.563 bits (449), Expect = 8.854e-52
Identity = 97/183 (53.01%), Postives = 122/183 (66.67%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKY 183
            MT   F+G    AFG P AMF FT+A +P+RII+L+ S+FFWLIS LISS  W+AVVPL+    FGLVFSV FQE FR LLY +L KA   + ++T       D  H+ AYV G GFG  SG F LVNVLAD++GPGT+G++ G    S +FFI SA  +L  +  HT WG+I FSA + KK+
Sbjct:    1 MTVMDFFGCAFLAFGPPLAMFTFTVAVEPIRIIILIASAFFWLISLLISSALWYAVVPLQDHLAFGLVFSVLFQEAFRYLLYWVLRKAERGLERVTTAHV--ADSRHVFAYVCGLGFGFMSGAFALVNVLADAVGPGTMGLRQG----SEYFFIISAATTLCFIFLHTFWGIIFFSAFDHKKW 177          

BLAST of EMLSAG00000000913 vs. nr
Match: gi|676454988|ref|XP_009053860.1| (hypothetical protein LOTGIDRAFT_116865 [Lottia gigantea] >gi|556106698|gb|ESO95350.1| hypothetical protein LOTGIDRAFT_116865 [Lottia gigantea])

HSP 1 Score: 177.948 bits (450), Expect = 1.003e-51
Identity = 108/206 (52.43%), Postives = 135/206 (65.53%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKP------HILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGIV 200
            MT   F+G    AFG P AMFIFTIA DP+RII+L+ S FFWL+S L+SS+ W+AVVPLR    FGLVFSV FQE+FR L Y LL KA   + K+++N P     P      HI+AYV G G+GI SG F +VNVLAD  GPGT+GIKG     S  FF+ SA  +L  +L HT WGVI F+A + K+Y+ +  V A H  +S +V
Sbjct:    1 MTLMEFFGCAFIAFGPPFAMFIFTIARDPLRIIVLIASGFFWLLSLLLSSILWYAVVPLRTSLAFGLVFSVIFQELFRFLFYKLLRKADEGLKKVSQNVPDEHITPKDINNKHIMAYVSGLGYGILSGAFSIVNVLADMAGPGTIGIKGD----SHFFFLTSAFLTLCFILLHTFWGVIFFNALDRKRYIFVAGVVASHMLVSCLV 202          

BLAST of EMLSAG00000000913 vs. nr
Match: gi|908506649|ref|XP_013064234.1| (PREDICTED: gamma-secretase subunit Aph-1-like [Biomphalaria glabrata] >gi|908506652|ref|XP_013064235.1| PREDICTED: gamma-secretase subunit Aph-1-like [Biomphalaria glabrata])

HSP 1 Score: 178.333 bits (451), Expect = 1.064e-51
Identity = 108/257 (42.02%), Postives = 151/257 (58.75%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKP------HILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGIVITSKPITTLRT--YFDHDVLNSNVIDCHGI--FHRRXGSVNSLKACFALRN 247
            MT   F+G    AFG P A+FIFTIA DP+R+I+L+ SSFFWLI+ LISS+ WFAVVPLR    FGLVFSV FQE+FR L Y ++  A   + K+++        P      HI+AYV G GFG+ SG F L+NVLAD  GPG++GI G     S++FF  S+  +L  +L HT WGVI F+  + K Y  +  V A H  +S + + ++  ++  +  Y    +    ++   GI  F+   GS+ ++K C   R 
Sbjct:    1 MTLMEFFGCTFIAFGPPIALFIFTIAKDPMRVIVLIASSFFWLIALLISSILWFAVVPLRETLAFGLVFSVLFQELFRFLFYKIMRLANEGLIKVSQQSDNSNITPRDFANTHIMAYVSGLGFGLMSGAFSLINVLADLWGPGSIGIHGD----SKYFFWSSSYLTLCFILLHTMWGVIFFAGMDRKCYFYVAYVVATHMLVSCLTLLNQLSSSTDSAIYLGPLIPAYIILVVSGIFAFYTAGGSLANIKNCVTCRK 253          

BLAST of EMLSAG00000000913 vs. nr
Match: gi|170029264|ref|XP_001842513.1| (gamma-secretase subunit Aph-1 [Culex quinquefasciatus] >gi|167881616|gb|EDS44999.1| gamma-secretase subunit Aph-1 [Culex quinquefasciatus])

HSP 1 Score: 176.407 bits (446), Expect = 3.306e-51
Identity = 101/193 (52.33%), Postives = 124/193 (64.25%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTENDPIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMH 193
            MT   F+G    AFG P AMF  TIA DP+RII+L+ +SFFWL+S L+SS  WFAV PLR + VFGL+ SV  QE FR L+Y LL K    + ++TE   I  D  HIL+YV G GFGI SG F LVN+LADS+GP T+G+K G    S  F + SA  SL ++L HT W VI FSAC+ K Y  +  V   H
Sbjct:    1 MTVVEFFGCSFLAFGPPVAMFALTIAHDPIRIIILIAASFFWLVSLLLSSTVWFAVFPLRDKLVFGLICSVFIQEGFRYLMYKLLRKTERGLQEVTEIARI-SDYKHILSYVSGLGFGIISGAFSLVNILADSVGPATVGLKAG----SSVFILISAAQSLCMILLHTFWSVIFFSACDVKNYYHIGYVVTSH 188          

BLAST of EMLSAG00000000913 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold934_size79169-snap-gene-0.22 (protein:Tk02399 transcript:maker-scaffold934_size79169-snap-gene-0.22-mRNA-1 annotation:"gamma-secretase subunit aph-1")

HSP 1 Score: 194.512 bits (493), Expect = 3.865e-62
Identity = 127/252 (50.40%), Postives = 170/252 (67.46%), Query Frame = 0

Query:    1 MTAWTFWGTFLTAFGAPSAMFIFTIAPDPVRIILLVLSSFFWLISXLISSLWWFAVVPLRHEPVFGLVFSVAFQEIFRILLYLLLFKARSFMSKLTEND--PIFGDKPHILAYVLGFGFGISSGLFGLVNVLADSLGPGTLGIKGGDFGVSRHFFIFSALFSLAIVLCHTAWGVIAFSACEEKKYLRLVTVWAMHYALSGIV---ITSKPITTLRTYFDHDVLNSNVIDCHGIFHRRXGSVNSLKACFALRN 247
            MTA TF+G  LTAFG   ++FIFTIA DPVRII+L+LS+FFWL+S L+SS  W  V PLR    FGL FSV FQE+FR+LLYLLL KA   M KLTEN+   IF +K HILAYV+G GFG+ +G+F LVN+LADSLGPGT+G KG     S+ FF+ SA  SLA++LCHT WGVI F+A ++ KY  +  VW  H+  SG+    ++   + ++   + + ++++ V      FH   GS+  L  CF+ ++
Sbjct:    1 MTALTFFGVALTAFGPALSLFIFTIARDPVRIIILILSAFFWLVSLLLSSGLWNVVYPLRDVLAFGLFFSVFFQEMFRLLLYLLLRKADRVMRKLTENEHTQIFENK-HILAYVVGLGFGMMAGVFSLVNILADSLGPGTVGWKGE----SQSFFMVSASLSLALILCHTCWGVITFAALDDGKYFWVALVWISHFLFSGLTLFNVSGLYVASVIPAYINLLISATV-----AFHCAGGSIPRLLKCFSCQS 242