EMLSAG00000004979, EMLSAG00000004979-687745 (gene) Lepeophtheirus salmonis
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Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of EMLSAG00000004979 vs. GO
Match: - (symbol:HMGCR "3-hydroxy-3-methylglutaryl-coenzyme A reductase" species:10029 "Cricetulus griseus" [GO:0005789 "endoplasmic reticulum membrane" evidence=TAS] [GO:0042282 "hydroxymethylglutaryl-CoA reductase activity" evidence=IDA] UniPathway:UPA00058 InterPro:IPR000731 InterPro:IPR002202 InterPro:IPR004554 InterPro:IPR004816 InterPro:IPR009023 InterPro:IPR009029 InterPro:IPR023074 InterPro:IPR023076 InterPro:IPR023282 Pfam:PF00368 PRINTS:PR00071 PROSITE:PS00066 PROSITE:PS00318 PROSITE:PS01192 PROSITE:PS50065 PROSITE:PS50156 GO:GO:0016021 GO:GO:0005789 GO:GO:0050661 GO:GO:0006695 GO:GO:0015936 GO:GO:0008299 KO:K00021 GO:GO:0004420 Gene3D:1.10.3270.10 Gene3D:3.30.70.420 Gene3D:3.90.770.10 PANTHER:PTHR10572 SUPFAM:SSF55035 SUPFAM:SSF56542 TIGRFAMs:TIGR00533 GO:GO:0042282 CTD:3156 HOVERGEN:HBG000453 TIGRFAMs:TIGR00920 EMBL:L00183 EMBL:L00166 EMBL:L00169 EMBL:L00170 EMBL:L00171 EMBL:L00173 EMBL:L00176 EMBL:L00177 EMBL:L00178 EMBL:L00179 EMBL:L00180 EMBL:L00181 EMBL:L00182 EMBL:X00494 PIR:A93328 RefSeq:XP_003508040.1 ProteinModelPortal:P00347 SMR:P00347 GeneID:100756363 KEGG:cge:100756363 Uniprot:P00347) HSP 1 Score: 618.616 bits (1594), Expect = 0.000e+0 Identity = 365/886 (41.20%), Postives = 523/886 (59.03%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTFVPLDGGS---------PEWSP-------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY----AFLLSMTAF------LLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLI-TSPQGQAKWNVK---RILETLPTQEPPSRTPLRVLAFPVLVLLHL--TCLQPPSLQLHIQNTPHIIISL------------SLVLLSYYF---YSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSRLKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDL-KDQEAQTTEECLVVSSSDEDRDETLSEDGSS------SHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAVGKL 841
G PWEV+ ++T + +++ G + P++ +++ + R +++L +Y Q + + +LGS +L +AGL+ +F+ S L G +A LLL D+ + + L ++ALS+ + + + ++R M L PT D L++ L+ + L ++ ++L FVF +P +S+ L L S +G+ W + R+LE + P ++++ LVL+H + PS Q T H +SL S+ L +Y S E +L L + Q + S LK+ + T + K+ ++ ++ +LV SE S P + +D++ + + +V + S L G+S + L + S PR E CL IL E+A++ L+D E++ LV +HI ++ LE ++ H RGV +RR+L+S + + + LPY+ ++Y VMGACCE+V+GYMP+PVG+ GPL LD K Y +PMATTEGCLVASTNRGC A+ GG +S++ DGM+RGPVVR P + + K WLE P + IKD+FDSTSRFARL KL V +AGR +Y+RF +KTGDAMGMNM+SK TE AL KL FPEMQI+++SGN CTDKKPAA+NWIEGRGK+VVCEA++PA +V +LKT+T A++D+N KN GSAMAGSIGG+NAH+ANIVTAI+IA GQDAAQN+GSSNC+TLME GP +DLYI+CTMPSIE+GT+GGGT L PQ +CL+MLGV+G +PGEN+RQLARI+CG V+AGELSLM+ALAAG LV SH+ HNRS + + L
Sbjct: 10 GLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQ--NSTTEHSKVSLGLDEDVSKRIEPSVSLWQFYLSKMISMDIEQVVTLSLAFLLAVKYIFFEQAETESTLSLKNPI------TSPVVTPKKAPDNCC--RREPLLV----RRSEKLSSVEEEPGVSQDRKVEVIKPLVVETESASRATFVLGASGTSPPVAARTQELEIELPSEPRPNEECLQIL-ESAEKGAKF-LSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSTKLPE-PSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRACDSAEVKAWLETPEGFAVIKDAFDSTSRFARLQKLHVTMAGRNLYIRFQSKTGDAMGMNMISKGTEKALLKLQEFFPEMQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMIDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDL 878
BLAST of EMLSAG00000004979 vs. GO
Match: - (symbol:Hmgcr "3-hydroxy-3-methylglutaryl-Coenzyme A reductase" species:10090 "Mus musculus" [GO:0004420 "hydroxymethylglutaryl-CoA reductase (NADPH) activity" evidence=IDA] [GO:0005778 "peroxisomal membrane" evidence=ISO] [GO:0005783 "endoplasmic reticulum" evidence=ISO] [GO:0005789 "endoplasmic reticulum membrane" evidence=IEA] [GO:0006629 "lipid metabolic process" evidence=IEA] [GO:0006694 "steroid biosynthetic process" evidence=IEA] [GO:0006695 "cholesterol biosynthetic process" evidence=ISO;IDA] [GO:0006743 "ubiquinone metabolic process" evidence=ISO] [GO:0008202 "steroid metabolic process" evidence=IEA] [GO:0008203 "cholesterol metabolic process" evidence=IEA] [GO:0008284 "positive regulation of cell proliferation" evidence=ISO] [GO:0008299 "isoprenoid biosynthetic process" evidence=ISO] [GO:0008542 "visual learning" evidence=IGI] [GO:0009790 "embryo development" evidence=IMP] [GO:0010664 "negative regulation of striated muscle cell apoptotic process" evidence=ISO] [GO:0010666 "positive regulation of cardiac muscle cell apoptotic process" evidence=ISO] [GO:0015936 "coenzyme A metabolic process" evidence=IEA] [GO:0016020 "membrane" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0016126 "sterol biosynthetic process" evidence=IEA] [GO:0016491 "oxidoreductase activity" evidence=IEA] [GO:0016616 "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" evidence=IEA] [GO:0032874 "positive regulation of stress-activated MAPK cascade" evidence=ISO] [GO:0042282 "hydroxymethylglutaryl-CoA reductase activity" evidence=ISO] [GO:0042803 "protein homodimerization activity" evidence=ISO] [GO:0043066 "negative regulation of apoptotic process" evidence=ISO] [GO:0043231 "intracellular membrane-bounded organelle" evidence=ISO] [GO:0043407 "negative regulation of MAP kinase activity" evidence=IGI] [GO:0045908 "negative regulation of vasodilation" evidence=ISO] [GO:0048643 "positive regulation of skeletal muscle tissue development" evidence=ISO] [GO:0048661 "positive regulation of smooth muscle cell proliferation" evidence=ISO] [GO:0050661 "NADP binding" evidence=IEA] [GO:0050662 "coenzyme binding" evidence=ISO] [GO:0051262 "protein tetramerization" evidence=ISO] [GO:0055114 "oxidation-reduction process" evidence=ISO] [GO:0061045 "negative regulation of wound healing" evidence=ISO] [GO:0061179 "negative regulation of insulin secretion involved in cellular response to glucose stimulus" evidence=ISO] [GO:0070374 "positive regulation of ERK1 and ERK2 cascade" evidence=ISO] [GO:0070402 "NADPH binding" evidence=ISO] UniPathway:UPA00058 InterPro:IPR000731 InterPro:IPR002202 InterPro:IPR004554 InterPro:IPR004816 InterPro:IPR009023 InterPro:IPR009029 InterPro:IPR023074 InterPro:IPR023076 InterPro:IPR023282 Pfam:PF00368 PRINTS:PR00071 PROSITE:PS00066 PROSITE:PS00318 PROSITE:PS01192 PROSITE:PS50065 PROSITE:PS50156 MGI:MGI:96159 GO:GO:0016021 GO:GO:0051262 GO:GO:0005789 GO:GO:0045471 GO:GO:0070374 GO:GO:0007568 GO:GO:0048661 GO:GO:0007584 GO:GO:0008542 GO:GO:0045908 GO:GO:0006695 GO:GO:0005778 GO:GO:0009790 GO:GO:0015936 GO:GO:0061179 GO:GO:0043407 GO:GO:0070402 GO:GO:0045445 GO:GO:0010664 GO:GO:0061045 GO:GO:0048643 GO:GO:0008299 GO:GO:0006743 GO:GO:0032874 GO:GO:0010666 EMBL:CH466567 eggNOG:COG1257 KO:K00021 GO:GO:0004420 Gene3D:1.10.3270.10 Gene3D:3.30.70.420 Gene3D:3.90.770.10 PANTHER:PTHR10572 SUPFAM:SSF55035 SUPFAM:SSF56542 TIGRFAMs:TIGR00533 GeneTree:ENSGT00390000006426 HOGENOM:HOG000183489 GO:GO:0042282 CTD:3156 HOVERGEN:HBG000453 OMA:PNEECLQ OrthoDB:EOG7GXP9T TreeFam:TF105362 TIGRFAMs:TIGR00920 ChiTaRS:Hmgcr GuidetoPHARMACOLOGY:639 EMBL:AC154851 EMBL:BC085083 EMBL:M62766 PIR:A43533 RefSeq:NP_032281.2 RefSeq:XP_006517594.1 RefSeq:XP_006517595.1 UniGene:Mm.316652 ProteinModelPortal:Q01237 SMR:Q01237 ChEMBL:CHEMBL2764 PhosphoSite:Q01237 PaxDb:Q01237 PRIDE:Q01237 Ensembl:ENSMUST00000022176 GeneID:15357 KEGG:mmu:15357 UCSC:uc007rnm.3 InParanoid:Q01237 SABIO-RK:Q01237 NextBio:287972 PRO:PR:Q01237 ArrayExpress:Q01237 CleanEx:MM_HMGCR Genevestigator:Q01237 Uniprot:Q01237) HSP 1 Score: 617.461 bits (1591), Expect = 0.000e+0 Identity = 359/903 (39.76%), Postives = 517/903 (57.25%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTFVPLDGGS---------PEWSP-------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY----AFLLSMTAF------LLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLI-TSPQGQAKWNVK---RILETLPTQEPPSRTPLRVLAFPVLVLLHL--TCLQPPSLQ-----------------------------------LHIQNTPHIIISLSLVLLSYYFYSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSR----LKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAVGKL 841
G PWEV+ ++T + +++ G + P++ +++ + R +++L +Y Q + + +LGS +L +AGL+ +F+ S L G +A LLL D+ + + L ++ALS+ + + + ++R M L PT D L++ L+ + L ++ ++L FVF +P +S+ L L S +G+ W + R+LE + P ++++ LVL+H + PS Q + + I +SL+ +L Y + + E ++L L+ + QD+ R ++ + +S D G AN ++ K LVV +++S + + V+ +S L L PR E CL IL ENA++ L+D E++ LV +HI ++ LE ++ H RGV +RR+L+S + + + LPY+ ++Y VMGACCE+V+GYMP+PVG+ GPL LD K Y +PMATTEGCLVASTNRGC A+S GG +S++ DGM+RGPVVR P + + K WLE P + IK++FDSTSRFARL KL V +AGR +Y+RF ++TGDAMGMNM+SK TE AL KL FP+MQI+++SGN CTDKKPAA+NWIEGRGK+VVCEA++PA +V +LKT+T A+VD+N KN GSAMAGSIGG+NAH+ANIVTAI+IA GQDAAQN+GSSNC+TLME GP +DLYI+CTMPSIE+GT+GGGT L PQ +CL+MLGV+G +PGEN+RQLARI+CG V+AGELSLM+ALAAG LV SH+ HNRS + + L
Sbjct: 10 GLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQAKVSLGLDEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLAFLLAVKYIFFEQAETESTLSLKNPITSPVVTSKKAQDNCCRREPLLVRRNQKLSSVEEDPG------ANQERKVEVIKPLVVEAETTSRATF--------------------VLGASVASPPSALGTQEPGIEL-----PIEPRPNEECLQIL-ENAEKGAKF-LSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSTKLAE-PSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMTRGPVVRLPRACDSAEVKTWLETPEGFAVIKEAFDSTSRFARLQKLHVTMAGRNLYIRFQSRTGDAMGMNMISKGTEKALLKLQEFFPDMQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDL 878
BLAST of EMLSAG00000004979 vs. GO
Match: - (symbol:HMGCR "Uncharacterized protein" species:9031 "Gallus gallus" [GO:0004420 "hydroxymethylglutaryl-CoA reductase (NADPH) activity" evidence=IEA] [GO:0005778 "peroxisomal membrane" evidence=IEA] [GO:0005789 "endoplasmic reticulum membrane" evidence=IEA] [GO:0006695 "cholesterol biosynthetic process" evidence=IEA] [GO:0008299 "isoprenoid biosynthetic process" evidence=IEA] [GO:0008542 "visual learning" evidence=IEA] [GO:0009790 "embryo development" evidence=IEA] [GO:0015936 "coenzyme A metabolic process" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0043407 "negative regulation of MAP kinase activity" evidence=IEA] [GO:0051262 "protein tetramerization" evidence=IEA] [GO:0070402 "NADPH binding" evidence=IEA] InterPro:IPR000731 InterPro:IPR002202 InterPro:IPR004554 InterPro:IPR004816 InterPro:IPR009023 InterPro:IPR009029 InterPro:IPR023074 InterPro:IPR023076 InterPro:IPR023282 Pfam:PF00368 PRINTS:PR00071 PROSITE:PS00066 PROSITE:PS00318 PROSITE:PS01192 PROSITE:PS50065 PROSITE:PS50156 GO:GO:0016021 GO:GO:0051262 GO:GO:0005789 GO:GO:0005778 GO:GO:0015936 GO:GO:0070402 GO:GO:0008299 GO:GO:0004420 Gene3D:1.10.3270.10 Gene3D:3.30.70.420 Gene3D:3.90.770.10 PANTHER:PTHR10572 SUPFAM:SSF55035 SUPFAM:SSF56542 TIGRFAMs:TIGR00533 GeneTree:ENSGT00390000006426 OrthoDB:EOG7GXP9T TreeFam:TF105362 TIGRFAMs:TIGR00920 EMBL:AC190414 Ensembl:ENSGALT00000024114 PRO:PR:E1C420 ArrayExpress:E1C420 Uniprot:E1C420) HSP 1 Score: 614.764 bits (1584), Expect = 0.000e+0 Identity = 352/891 (39.51%), Postives = 521/891 (58.47%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTFVPLDGGSP--EWSP--------------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY----AFLLSMTAF------LLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLI-TSPQGQAKWNVK---RILETLPTQEPPSRTPLRVLAFPVLVLLHLT---CLQPPSLQLHIQNT------------PH-------------------IIISLSLVLLSYYFYSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSRLKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTL 836
G PWEV+ ++T + +++ G W+ +++ + R +++L +Y Q + + +LGS +L +AGL+ +F+ S L G +A LLL D+ + + L ++ALS+ + + + +SR M L PT D L++ L+ + L ++ ++L FVF +P +S+ L L S +G+ W + R+LE + P ++++ LVL+H +P S ++N P+ I + L+ +L Y + + E ++L L+ T + ++ ++ R GL K++ + ++++ + G+ +EV P L E+ T +V S + E+ L++ L PRSIE C+ IL + + LTD EV++LV +HI ++ LE ++ RGV +RR+++S++ + + LPY++++Y V+GACCE+V+GYMP+PVG+ GPL LDNK + +PMATTEGCLVASTNRGC A+ GG S+I DGM+RGPVVR P+ A + K WLE P ++ +K++FDSTSRFARL KL + LAGR +Y+RF +KTGDAMGMNM+SK TE AL +L+ FP++Q+I+ISGN CTDKKPAA+NWIEGRGKSVVCEA++PA +V+ +LKT+T +V++N KN GSAMAGSIGG+NAH+ANIVTAI+IA GQDAAQN+GSSNC+TLME G +DLYI+CTMPSIE+GT+GGGT L PQ +CL+MLGV+G +PGEN+RQLA+I+C V+AGELSLM+ALAAG LV SH+ HNRS +
Sbjct: 3 GLFVASHPWEVIVGTVTLTICMMSMKMFTGNDKICGWNYECPKLEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENISRGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIAEPASQNGTVENAVGLDENAPKRIEPNVSLWQFYLSRMASMDIEQVITLGLAFLLAVKYIFFEQAETESTLSLKNPITSPVTVQ--------KKVPENCCRKQS------GLLKNSQKTNTVEEAFVAKDGN--------AEVIKPVLA--ESSTKATFVVGSCNPEETSSVLNKKEEEIEL-----PKEPRSIEECVRILGSTEKGAKF--LTDAEVISLVNAKHIPAYKLETLMETQERGVSIRRQMLSQKLPE-PSSLQYLPYRNYNYSLVLGACCENVIGYMPIPVGVAGPLYLDNKEFQVPMATTEGCLVASTNRGCRAICLGGGARSRILADGMTRGPVVRLPSACQAAEVKAWLESPEGFKIVKEAFDSTSRFARLQKLLISLAGRNLYIRFQSKTGDAMGMNMISKGTEKALARLNEEFPDLQVIAISGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVKEVLKTTTEDIVEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMERTGSTSEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGASQDNPGENARQLAKIVCATVMAGELSLMAALAAGHLVKSHMIHNRSKI 861
BLAST of EMLSAG00000004979 vs. GO
Match: - (symbol:HMGCR "3-hydroxy-3-methylglutaryl-coenzyme A reductase" species:9606 "Homo sapiens" [GO:0004420 "hydroxymethylglutaryl-CoA reductase (NADPH) activity" evidence=IEA] [GO:0005515 "protein binding" evidence=IPI] [GO:0005778 "peroxisomal membrane" evidence=IDA] [GO:0005783 "endoplasmic reticulum" evidence=IDA] [GO:0005789 "endoplasmic reticulum membrane" evidence=TAS] [GO:0006695 "cholesterol biosynthetic process" evidence=TAS] [GO:0006743 "ubiquinone metabolic process" evidence=IEA] [GO:0007568 "aging" evidence=IEA] [GO:0007584 "response to nutrient" evidence=IEA] [GO:0008299 "isoprenoid biosynthetic process" evidence=IEA] [GO:0008542 "visual learning" evidence=IEA] [GO:0009790 "embryo development" evidence=IEA] [GO:0010664 "negative regulation of striated muscle cell apoptotic process" evidence=IEA] [GO:0010666 "positive regulation of cardiac muscle cell apoptotic process" evidence=IEA] [GO:0015936 "coenzyme A metabolic process" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0032874 "positive regulation of stress-activated MAPK cascade" evidence=IEA] [GO:0042282 "hydroxymethylglutaryl-CoA reductase activity" evidence=IDA] [GO:0042803 "protein homodimerization activity" evidence=IEA] [GO:0043407 "negative regulation of MAP kinase activity" evidence=IEA] [GO:0044255 "cellular lipid metabolic process" evidence=TAS] [GO:0044281 "small molecule metabolic process" evidence=TAS] [GO:0045445 "myoblast differentiation" evidence=IEA] [GO:0045471 "response to ethanol" evidence=IEA] [GO:0045908 "negative regulation of vasodilation" evidence=IEA] [GO:0048643 "positive regulation of skeletal muscle tissue development" evidence=IEA] [GO:0048661 "positive regulation of smooth muscle cell proliferation" evidence=IEA] [GO:0050662 "coenzyme binding" evidence=IDA] [GO:0051262 "protein tetramerization" evidence=IDA] [GO:0061045 "negative regulation of wound healing" evidence=IEA] [GO:0061179 "negative regulation of insulin secretion involved in cellular response to glucose stimulus" evidence=IEA] [GO:0070374 "positive regulation of ERK1 and ERK2 cascade" evidence=IEA] [GO:0070402 "NADPH binding" evidence=IDA] Reactome:REACT_111217 UniPathway:UPA00058 InterPro:IPR000731 InterPro:IPR002202 InterPro:IPR004554 InterPro:IPR004816 InterPro:IPR009023 InterPro:IPR009029 InterPro:IPR023074 InterPro:IPR023076 InterPro:IPR023282 Pfam:PF00368 PRINTS:PR00071 PROSITE:PS00066 PROSITE:PS00318 PROSITE:PS01192 PROSITE:PS50065 PROSITE:PS50156 GO:GO:0016021 GO:GO:0051262 DrugBank:DB00157 GO:GO:0005789 GO:GO:0045471 GO:GO:0070374 GO:GO:0007568 GO:GO:0048661 GO:GO:0007584 GO:GO:0008542 GO:GO:0045908 GO:GO:0044255 GO:GO:0006695 GO:GO:0005778 DrugBank:DB01098 GO:GO:0009790 GO:GO:0015936 GO:GO:0061179 GO:GO:0043407 GO:GO:0070402 DrugBank:DB01076 DrugBank:DB00641 GO:GO:0045445 GO:GO:0010664 EMBL:AC008897 GO:GO:0061045 GO:GO:0048643 GO:GO:0008299 GO:GO:0006743 DrugBank:DB01095 DrugBank:DB00439 DrugBank:DB00227 DrugBank:DB00175 GO:GO:0032874 DrugBank:DB01393 GO:GO:0010666 eggNOG:COG1257 KO:K00021 GO:GO:0004420 Gene3D:1.10.3270.10 Gene3D:3.30.70.420 Gene3D:3.90.770.10 PANTHER:PTHR10572 SUPFAM:SSF55035 SUPFAM:SSF56542 TIGRFAMs:TIGR00533 HOGENOM:HOG000183489 GO:GO:0042282 CTD:3156 HOVERGEN:HBG000453 OMA:PNEECLQ OrthoDB:EOG7GXP9T TreeFam:TF105362 TIGRFAMs:TIGR00920 ChiTaRS:Hmgcr EMBL:M11058 EMBL:AF273765 EMBL:AF273754 EMBL:AF273755 EMBL:AF273756 EMBL:AF273757 EMBL:AF273758 EMBL:AF273759 EMBL:AF273760 EMBL:AF273761 EMBL:AF273762 EMBL:AF273763 EMBL:AF273764 EMBL:AY321356 EMBL:AK296499 EMBL:BC033692 PIR:A00356 RefSeq:NP_000850.1 RefSeq:NP_001124468.1 RefSeq:XP_005248549.1 UniGene:Hs.628096 UniGene:Hs.643495 PDB:1DQ8 PDB:1DQ9 PDB:1DQA PDB:1HW8 PDB:1HW9 PDB:1HWI PDB:1HWJ PDB:1HWK PDB:1HWL PDB:2Q1L PDB:2Q6B PDB:2Q6C PDB:2R4F PDB:3BGL PDB:3CCT PDB:3CCW PDB:3CCZ PDB:3CD0 PDB:3CD5 PDB:3CD7 PDB:3CDA PDB:3CDB PDBsum:1DQ8 PDBsum:1DQ9 PDBsum:1DQA PDBsum:1HW8 PDBsum:1HW9 PDBsum:1HWI PDBsum:1HWJ PDBsum:1HWK PDBsum:1HWL PDBsum:2Q1L PDBsum:2Q6B PDBsum:2Q6C PDBsum:2R4F PDBsum:3BGL PDBsum:3CCT PDBsum:3CCW PDBsum:3CCZ PDBsum:3CD0 PDBsum:3CD5 PDBsum:3CD7 PDBsum:3CDA PDBsum:3CDB ProteinModelPortal:P04035 SMR:P04035 BioGrid:109399 IntAct:P04035 STRING:9606.ENSP00000287936 BindingDB:P04035 ChEMBL:CHEMBL402 GuidetoPHARMACOLOGY:639 TCDB:2.A.6.6.5 PhosphoSite:P04035 DMDM:123343 PaxDb:P04035 PRIDE:P04035 DNASU:3156 Ensembl:ENST00000287936 Ensembl:ENST00000343975 Ensembl:ENST00000511206 GeneID:3156 KEGG:hsa:3156 UCSC:uc003kdp.3 UCSC:uc003kdq.3 GeneCards:GC05P074635 HGNC:HGNC:5006 HPA:CAB016797 HPA:HPA008338 MIM:142910 neXtProt:NX_P04035 PharmGKB:PA189 InParanoid:P04035 PhylomeDB:P04035 BioCyc:MetaCyc:HS03652-MONOMER SABIO-RK:P04035 EvolutionaryTrace:P04035 GeneWiki:HMG-CoA_reductase GenomeRNAi:3156 NextBio:12500 PRO:PR:P04035 ArrayExpress:P04035 Bgee:P04035 CleanEx:HS_HMGCR Genevestigator:P04035 Uniprot:P04035) HSP 1 Score: 614.379 bits (1583), Expect = 0.000e+0 Identity = 355/899 (39.49%), Postives = 516/899 (57.40%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTFVPLDGGS---------PEWSP-------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY----AFLLSMTAF------LLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLI-TSPQGQAKWNVK---RILETLPTQEPPSRTPLRVLAFPVLVLLHL--TCLQPPSLQLHIQNTPH-----------------------------------IIISLSLVLLSYYFYSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSRLKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAVGKL 841
G PWEV+ ++T + +++ G + P++ +++ + R +++L +Y Q + + +LGS +L +AGL+ +F+ S L G +A LLL D+ + + L ++ALS+ + + + ++R M L PT D L++ L+ + L ++ ++L FVF +P +S+ L L S +G+ W + R+LE + P ++++ LVL+H + PS Q +T I +SL+L+L Y + + E ++L L+ + + D+ R + L R +Q D S + + + + + EV P + + + +V +SS D L L PR E CL IL NA++ L+D E++ LV +HI ++ LE ++ H RGV +RR+L+S++ + + LPY+ ++Y VMGACCE+V+GYMP+PVG+ GPL LD K + +PMATTEGCLVASTNRGC A+ GG +S++ DGM+RGPVVR P + + K WLE + IK++FDSTSRFARL KL +AGR +Y+RF +++GDAMGMNM+SK TE AL+KLH FPEMQI+++SGN CTDKKPAA+NWIEGRGKSVVCEA++PA +V +LKT+T A++++N KN GSAMAGSIGG+NAH+ANIVTAI+IA GQDAAQN+GSSNC+TLME GP +DLYI+CTMPSIE+GT+GGGT L PQ +CL+MLGV+G +PGEN+RQLARI+CG V+AGELSLM+ALAAG LV SH+ HNRS + + L
Sbjct: 10 GLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSLKNPITSPVVTQKKVPDNCCRR-EPMLVRNNQKCD-------SVEEETGINRERKV-------------EVIKPLVAETDTPNRATFVVGNSSLLDTSSVLVTQEPEIEL-----PREPRPNEECLQILG-NAEKGAKF-LSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSKKLSE-PSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDEKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRACDSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSRSGDAMGMNMISKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREVLKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDL 879
BLAST of EMLSAG00000004979 vs. GO
Match: - (symbol:Hmgcr "3-hydroxy-3-methylglutaryl-coenzyme A reductase" species:10116 "Rattus norvegicus" [GO:0004420 "hydroxymethylglutaryl-CoA reductase (NADPH) activity" evidence=IEA] [GO:0005778 "peroxisomal membrane" evidence=IEA] [GO:0005789 "endoplasmic reticulum membrane" evidence=IEA] [GO:0008542 "visual learning" evidence=IEA] [GO:0009790 "embryo development" evidence=IEA] [GO:0015936 "coenzyme A metabolic process" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0043407 "negative regulation of MAP kinase activity" evidence=IEA] [GO:0051262 "protein tetramerization" evidence=IEA] [GO:0070402 "NADPH binding" evidence=IEA] UniPathway:UPA00058 InterPro:IPR000731 InterPro:IPR002202 InterPro:IPR004554 InterPro:IPR004816 InterPro:IPR009023 InterPro:IPR009029 InterPro:IPR023074 InterPro:IPR023076 InterPro:IPR023282 Pfam:PF00368 PRINTS:PR00071 PROSITE:PS00066 PROSITE:PS00318 PROSITE:PS01192 PROSITE:PS50065 PROSITE:PS50156 RGD:2803 GO:GO:0043231 GO:GO:0016021 GO:GO:0042803 GO:GO:0051262 GO:GO:0005789 GO:GO:0045471 GO:GO:0070374 GO:GO:0007568 GO:GO:0048661 GO:GO:0007584 GO:GO:0008542 GO:GO:0045908 GO:GO:0006695 GO:GO:0005778 GO:GO:0009790 GO:GO:0015936 GO:GO:0061179 GO:GO:0043407 GO:GO:0070402 GO:GO:0045445 GO:GO:0010664 GO:GO:0061045 GO:GO:0048643 GO:GO:0006743 GO:GO:0032874 GO:GO:0010666 GO:GO:0010142 eggNOG:COG1257 KO:K00021 GO:GO:0004420 Gene3D:1.10.3270.10 Gene3D:3.30.70.420 Gene3D:3.90.770.10 PANTHER:PTHR10572 SUPFAM:SSF55035 SUPFAM:SSF56542 TIGRFAMs:TIGR00533 GeneTree:ENSGT00390000006426 HOGENOM:HOG000183489 GO:GO:0042282 CTD:3156 HOVERGEN:HBG000453 OMA:PNEECLQ OrthoDB:EOG7GXP9T TreeFam:TF105362 TIGRFAMs:TIGR00920 GuidetoPHARMACOLOGY:639 EMBL:M29249 EMBL:BC064654 EMBL:X55286 PIR:S33175 RefSeq:NP_037266.2 UniGene:Rn.9437 ProteinModelPortal:P51639 SMR:P51639 BioGrid:247704 MINT:MINT-1347783 BindingDB:P51639 ChEMBL:CHEMBL3247 PhosphoSite:P51639 PaxDb:P51639 PRIDE:P51639 Ensembl:ENSRNOT00000022055 GeneID:25675 KEGG:rno:25675 InParanoid:P51639 NextBio:607623 PRO:PR:P51639 Genevestigator:P51639 Uniprot:P51639) HSP 1 Score: 613.609 bits (1581), Expect = 0.000e+0 Identity = 358/904 (39.60%), Postives = 513/904 (56.75%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTFVPLDGGS---------PEWSP-------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY----AFLLSMTAF------LLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLI-TSPQGQAKWNVK---RILETLPTQEPPSRTPLRVLAFPVLVLL--HLTCLQPPSLQ-----------------------------------LHIQNTPHIIISLSLVLLSYYFYSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSR----LKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHH------SPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTL 836
G PWEV+ ++T + +++ G + P++ +++ + R +++L +Y Q + + +LGS +L +AGL+ +F+ S L G +A LLL D+ + + L ++ALS+ + + + ++R M L PT D L++ L+ + L ++ ++L FVF +P +S+ L L S +G+ W + R+LE + P ++++ LVL+ H + PS Q + + I +SL+L+L Y + + E ++L L+ + QD+ R ++ + +S D G+ N ++ K LV ++S + + L +S L G S PR E CL IL E+A++ L+D E++ LV +HI ++ LE ++ H RGV +RR+L+S + + + LPY+ ++Y VMGACCE+V+GYMP+PVG+ GPL LD K Y +PMATTEGCLVASTNRGC A+S GG +S++ DGMSRGPVVR P + + K WLE P + +K++FDSTSRFARL KL V LAGR +Y+R +KTGDAMGMNM+SK TE AL KL FPE+QI+++SGN CTDKKPAA+NWIEGRGK+VVCEA++PA +V +LKT+T A+VD+N KN GSAMAGSIGG+NAH+ANIVTAI+IA GQDAAQN+GSSNC+TLME GP +DLYI+CTMPSIE+GT+GGGT L PQ +CL+MLGV+G +PGEN+RQLARI+CG V+AGELSLM+ALAAG LV SH+ HNRS +
Sbjct: 10 GLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGV------NQDRKVEVIKPLVAEAETSGRATF-------------------------------VLGASAASPPLALGAQEPGIELPSEPRPNEECLQIL-ESAEKGAKF-LSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAE-PSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKI 873
BLAST of EMLSAG00000004979 vs. GO
Match: - (symbol:Hmgcr "3-hydroxy-3-methylglutaryl-CoA reductase" species:10116 "Rattus norvegicus" [GO:0004420 "hydroxymethylglutaryl-CoA reductase (NADPH) activity" evidence=IEA;ISO] [GO:0005778 "peroxisomal membrane" evidence=IEA;ISO] [GO:0005783 "endoplasmic reticulum" evidence=ISO] [GO:0005789 "endoplasmic reticulum membrane" evidence=IEA] [GO:0006695 "cholesterol biosynthetic process" evidence=ISO;IDA] [GO:0006743 "ubiquinone metabolic process" evidence=IMP] [GO:0007568 "aging" evidence=IEP] [GO:0007584 "response to nutrient" evidence=IEP] [GO:0008284 "positive regulation of cell proliferation" evidence=IMP] [GO:0008299 "isoprenoid biosynthetic process" evidence=IDA] [GO:0008542 "visual learning" evidence=IEA;ISO] [GO:0009790 "embryo development" evidence=IEA;ISO] [GO:0010142 "farnesyl diphosphate biosynthetic process, mevalonate pathway" evidence=TAS] [GO:0010664 "negative regulation of striated muscle cell apoptotic process" evidence=IMP] [GO:0010666 "positive regulation of cardiac muscle cell apoptotic process" evidence=IMP] [GO:0015936 "coenzyme A metabolic process" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0032874 "positive regulation of stress-activated MAPK cascade" evidence=IMP] [GO:0042282 "hydroxymethylglutaryl-CoA reductase activity" evidence=ISO;IDA] [GO:0042803 "protein homodimerization activity" evidence=IDA] [GO:0043066 "negative regulation of apoptotic process" evidence=IMP] [GO:0043231 "intracellular membrane-bounded organelle" evidence=IDA] [GO:0043407 "negative regulation of MAP kinase activity" evidence=IEA;ISO] [GO:0045445 "myoblast differentiation" evidence=IEP] [GO:0045471 "response to ethanol" evidence=IEP] [GO:0045908 "negative regulation of vasodilation" evidence=IMP] [GO:0048643 "positive regulation of skeletal muscle tissue development" evidence=IMP] [GO:0048661 "positive regulation of smooth muscle cell proliferation" evidence=IMP] [GO:0050662 "coenzyme binding" evidence=ISO] [GO:0051262 "protein tetramerization" evidence=IEA;ISO] [GO:0055114 "oxidation-reduction process" evidence=ISO] [GO:0061045 "negative regulation of wound healing" evidence=IMP] [GO:0061179 "negative regulation of insulin secretion involved in cellular response to glucose stimulus" evidence=IMP] [GO:0070374 "positive regulation of ERK1 and ERK2 cascade" evidence=IMP] [GO:0070402 "NADPH binding" evidence=IEA;ISO] UniPathway:UPA00058 InterPro:IPR000731 InterPro:IPR002202 InterPro:IPR004554 InterPro:IPR004816 InterPro:IPR009023 InterPro:IPR009029 InterPro:IPR023074 InterPro:IPR023076 InterPro:IPR023282 Pfam:PF00368 PRINTS:PR00071 PROSITE:PS00066 PROSITE:PS00318 PROSITE:PS01192 PROSITE:PS50065 PROSITE:PS50156 RGD:2803 GO:GO:0043231 GO:GO:0016021 GO:GO:0042803 GO:GO:0051262 GO:GO:0005789 GO:GO:0045471 GO:GO:0070374 GO:GO:0007568 GO:GO:0048661 GO:GO:0007584 GO:GO:0008542 GO:GO:0045908 GO:GO:0006695 GO:GO:0005778 GO:GO:0009790 GO:GO:0015936 GO:GO:0061179 GO:GO:0043407 GO:GO:0070402 GO:GO:0045445 GO:GO:0010664 GO:GO:0061045 GO:GO:0048643 GO:GO:0006743 GO:GO:0032874 GO:GO:0010666 GO:GO:0010142 eggNOG:COG1257 KO:K00021 GO:GO:0004420 Gene3D:1.10.3270.10 Gene3D:3.30.70.420 Gene3D:3.90.770.10 PANTHER:PTHR10572 SUPFAM:SSF55035 SUPFAM:SSF56542 TIGRFAMs:TIGR00533 GeneTree:ENSGT00390000006426 HOGENOM:HOG000183489 GO:GO:0042282 CTD:3156 HOVERGEN:HBG000453 OMA:PNEECLQ OrthoDB:EOG7GXP9T TreeFam:TF105362 TIGRFAMs:TIGR00920 GuidetoPHARMACOLOGY:639 EMBL:M29249 EMBL:BC064654 EMBL:X55286 PIR:S33175 RefSeq:NP_037266.2 UniGene:Rn.9437 ProteinModelPortal:P51639 SMR:P51639 BioGrid:247704 MINT:MINT-1347783 BindingDB:P51639 ChEMBL:CHEMBL3247 PhosphoSite:P51639 PaxDb:P51639 PRIDE:P51639 Ensembl:ENSRNOT00000022055 GeneID:25675 KEGG:rno:25675 InParanoid:P51639 NextBio:607623 PRO:PR:P51639 Genevestigator:P51639 Uniprot:P51639) HSP 1 Score: 613.609 bits (1581), Expect = 0.000e+0 Identity = 358/904 (39.60%), Postives = 513/904 (56.75%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTFVPLDGGS---------PEWSP-------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY----AFLLSMTAF------LLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLI-TSPQGQAKWNVK---RILETLPTQEPPSRTPLRVLAFPVLVLL--HLTCLQPPSLQ-----------------------------------LHIQNTPHIIISLSLVLLSYYFYSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSR----LKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHH------SPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTL 836
G PWEV+ ++T + +++ G + P++ +++ + R +++L +Y Q + + +LGS +L +AGL+ +F+ S L G +A LLL D+ + + L ++ALS+ + + + ++R M L PT D L++ L+ + L ++ ++L FVF +P +S+ L L S +G+ W + R+LE + P ++++ LVL+ H + PS Q + + I +SL+L+L Y + + E ++L L+ + QD+ R ++ + +S D G+ N ++ K LV ++S + + L +S L G S PR E CL IL E+A++ L+D E++ LV +HI ++ LE ++ H RGV +RR+L+S + + + LPY+ ++Y VMGACCE+V+GYMP+PVG+ GPL LD K Y +PMATTEGCLVASTNRGC A+S GG +S++ DGMSRGPVVR P + + K WLE P + +K++FDSTSRFARL KL V LAGR +Y+R +KTGDAMGMNM+SK TE AL KL FPE+QI+++SGN CTDKKPAA+NWIEGRGK+VVCEA++PA +V +LKT+T A+VD+N KN GSAMAGSIGG+NAH+ANIVTAI+IA GQDAAQN+GSSNC+TLME GP +DLYI+CTMPSIE+GT+GGGT L PQ +CL+MLGV+G +PGEN+RQLARI+CG V+AGELSLM+ALAAG LV SH+ HNRS +
Sbjct: 10 GLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGV------NQDRKVEVIKPLVAEAETSGRATF-------------------------------VLGASAASPPLALGAQEPGIELPSEPRPNEECLQIL-ESAEKGAKF-LSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAE-PSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKI 873
BLAST of EMLSAG00000004979 vs. GO
Match: - (symbol:HMGCR "3-hydroxy-3-methylglutaryl-coenzyme A reductase" species:9913 "Bos taurus" [GO:0004420 "hydroxymethylglutaryl-CoA reductase (NADPH) activity" evidence=IEA] [GO:0005778 "peroxisomal membrane" evidence=IEA] [GO:0005789 "endoplasmic reticulum membrane" evidence=IEA] [GO:0006695 "cholesterol biosynthetic process" evidence=IEA] [GO:0008299 "isoprenoid biosynthetic process" evidence=IEA] [GO:0008542 "visual learning" evidence=IEA] [GO:0009790 "embryo development" evidence=IEA] [GO:0015936 "coenzyme A metabolic process" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0043407 "negative regulation of MAP kinase activity" evidence=IEA] [GO:0051262 "protein tetramerization" evidence=IEA] [GO:0070402 "NADPH binding" evidence=IEA] UniPathway:UPA00058 InterPro:IPR000731 InterPro:IPR002202 InterPro:IPR004554 InterPro:IPR004816 InterPro:IPR009023 InterPro:IPR009029 InterPro:IPR023074 InterPro:IPR023076 InterPro:IPR023282 Pfam:PF00368 PRINTS:PR00071 PROSITE:PS00066 PROSITE:PS00318 PROSITE:PS01192 PROSITE:PS50065 PROSITE:PS50156 GO:GO:0016021 GO:GO:0051262 GO:GO:0005789 GO:GO:0008542 GO:GO:0006695 GO:GO:0005778 GO:GO:0009790 GO:GO:0015936 GO:GO:0043407 GO:GO:0070402 GO:GO:0008299 eggNOG:COG1257 KO:K00021 GO:GO:0004420 Gene3D:1.10.3270.10 Gene3D:3.30.70.420 Gene3D:3.90.770.10 PANTHER:PTHR10572 SUPFAM:SSF55035 SUPFAM:SSF56542 TIGRFAMs:TIGR00533 GeneTree:ENSGT00390000006426 HOGENOM:HOG000183489 EMBL:DAAA02027738 EMBL:BC153262 RefSeq:NP_001099083.1 UniGene:Bt.11465 STRING:9913.ENSBTAP00000010315 Ensembl:ENSBTAT00000010315 GeneID:407159 KEGG:bta:407159 CTD:3156 HOVERGEN:HBG000453 InParanoid:A7Z064 OMA:PNEECLQ OrthoDB:EOG7GXP9T TreeFam:TF105362 NextBio:20818419 ArrayExpress:A7Z064 TIGRFAMs:TIGR00920 Uniprot:A7Z064) HSP 1 Score: 612.838 bits (1579), Expect = 0.000e+0 Identity = 357/887 (40.25%), Postives = 519/887 (58.51%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTFVPLDGGSP--EWSP--------------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY----AFLLSMTAF------LLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLI-TSPQGQAKWNVK---RILETLPTQEPPSRTPLRVLAFPVLVLL--HLTCLQPPSLQLHIQNTPHIIISL----------SLVLLSYYF---YSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSRLKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHL---LSGDHHSP-------PRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAVGKL 841
G PWEV+ ++T + +++ G + W+ +++ + R +++L +Y Q + + +LGS +L +AGL+ +F+ S L G +A LLL D+ + + L ++ALS+ + + + ++R M L PT D L++ L+ + L ++ ++L FVF +P +S+ L L S +G+ W + R+LE + P ++++ LVL+ H + PS Q + + + L S+ L +Y S E +L L + Q + S LK+ + + D + ++V +D + E K++E + +++ +D T G+SS L L + P PR E CL IL ENA++ L+D E++ LV +HI ++ LE ++ H RGV +RR+L+S++ + + LPY+ ++Y VMGACCE+V+GYMP+PVG+ GPL LD K + +PMATTEGCLVASTNRGC A+ GG +S++ DGM+RGPVVRFP + + K WLE P + IK++FDSTSRFARL KL + +AGR +Y+RF +++GDAMGMNM+SK TE AL+KL FPEMQI+++SGN CTDKKPAA+NWIEGRGKSVVCEA++PA +V +LKT+T A++++N KN GSAMAGSIGG+NAH+ANIVTAI+IA GQDAAQN+GSSNC+TLME GP +DLYI+CTMPSIE+GT+GGGT L PQ +CL+MLGV+G +PGEN+RQLARI+CG V+AGELSLM+ALAAG LV SH+ HNRS + + L
Sbjct: 10 GLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKLEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLVDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADNSKVSLGLDENVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSP---------VVTQKKITDDCCRRDPVLVRNDQKFHAMEEETR----KNRERKVEVIKPLLAENDTSHRATFVV-GNSSLLGTSLELETQEPEMELPVEPRPNEECLQIL-ENAEKGAKF-LSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSKKLPE-PSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRFPRACDSAEVKAWLETPEGFTVIKEAFDSTSRFARLQKLHMSVAGRNLYIRFQSRSGDAMGMNMISKGTEKALSKLQEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREVLKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACRDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMIHNRSKINLQDL 879
BLAST of EMLSAG00000004979 vs. GO
Match: - (symbol:HMGCR "3-hydroxy-3-methylglutaryl-coenzyme A reductase" species:9823 "Sus scrofa" [GO:0004420 "hydroxymethylglutaryl-CoA reductase (NADPH) activity" evidence=IEA] [GO:0005778 "peroxisomal membrane" evidence=IEA] [GO:0005789 "endoplasmic reticulum membrane" evidence=IEA] [GO:0006695 "cholesterol biosynthetic process" evidence=IEA] [GO:0008299 "isoprenoid biosynthetic process" evidence=IEA] [GO:0008542 "visual learning" evidence=IEA] [GO:0009790 "embryo development" evidence=IEA] [GO:0015936 "coenzyme A metabolic process" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0043407 "negative regulation of MAP kinase activity" evidence=IEA] [GO:0051262 "protein tetramerization" evidence=IEA] [GO:0070402 "NADPH binding" evidence=IEA] InterPro:IPR000731 InterPro:IPR002202 InterPro:IPR004554 InterPro:IPR004816 InterPro:IPR009023 InterPro:IPR009029 InterPro:IPR023074 InterPro:IPR023076 InterPro:IPR023282 Pfam:PF00368 PRINTS:PR00071 PROSITE:PS00066 PROSITE:PS00318 PROSITE:PS01192 PROSITE:PS50065 PROSITE:PS50156 GO:GO:0016021 GO:GO:0051262 GO:GO:0005789 GO:GO:0008542 GO:GO:0006695 GO:GO:0005778 GO:GO:0009790 GO:GO:0015936 GO:GO:0043407 GO:GO:0070402 GO:GO:0008299 GO:GO:0004420 Gene3D:1.10.3270.10 Gene3D:3.30.70.420 Gene3D:3.90.770.10 PANTHER:PTHR10572 SUPFAM:SSF55035 SUPFAM:SSF56542 TIGRFAMs:TIGR00533 GeneTree:ENSGT00390000006426 OMA:PNEECLQ OrthoDB:EOG7GXP9T TreeFam:TF105362 TIGRFAMs:TIGR00920 EMBL:FP312763 Ensembl:ENSSSCT00000015381 Uniprot:F1S2I4) HSP 1 Score: 611.683 bits (1576), Expect = 0.000e+0 Identity = 351/910 (38.57%), Postives = 515/910 (56.59%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTFVPLDGGS---------PEWSP-------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY----AFLLSMTAF------LLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLI-TSPQGQAKWNVK---RILETLPTQEPPSRTPLRVLAFPVLVLLHL--TCLQPPSLQLHIQNTPHIIISL----------SLVLLSYYF-------------------------YSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSR----LKDDL------DRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLK-DQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAVGKL 841
G PWEV+ ++T + +++ G P++ +++ + R +++L +Y Q + + +LGS +L +AGL+ +F+ S L G +A LLL D+ + + L ++ALS+ + + + ++R M L PT D L++ L+ + L ++ ++L FVF +P +S+ L L S +G+ W + R+LE + P ++++ LVL+H + PS Q + + + L S+ L +Y + + E ++L L+ + + D R +++D + A + + + + K + +D VVG+ + S E+ P+++ E + EECL + + E + LS D E++ LV +HI ++ LE ++ H RGV +RR+L+S++ + + LPY+ ++Y VMGACCE+V+GYMP+PVG+ GPL LD K + +PMATTEGCLVASTNRGC A+ GG +S+I DGM+RGPVVRFP + + K WLE P + IK++FDSTSRFARL KL++ +AGR +Y+RF +++GDAMGMNM+SK TE AL+KLH FPEMQI+++SGN CTDKKPAAVNWIEGRGKSVVCEA++PA +V +LKT+T A+V++N KN GSAMAGSIGG+NAH+ANIVTAI+IA GQDAAQN+GSSNC+TLME GP +DLYI+CTMPSIE+GT+GGGT L PQ +CL+MLGV+G +PGEN+RQLARI+CG V+AGELSLM+ALAAG LV SH+ HNRS + + L
Sbjct: 10 GLFVASHPWEVIVGTVTLTICMMSMNMFTGNDKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKIIMSLGLVLVHAHSRWIADPSPQNSTADNSKVSLGLDENVSKRIEPSVSLWQFYLSKMISMDIEQVITLTLALLLAVKYIFFEQAETESTLSLKNPITSPVVTQKKVTDDCCRREPTLVRNDQKFHTVEEEARINRERKVEVIKPLVAETDTSSRPTFVVGNSTLDSSLELEMQEPEIQIPSEPRPNEECLQILGNAEKGAKFLS----------------------------------------DAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSKKLPE-PSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRILADGMTRGPVVRFPRACDSAEVKAWLETPEGFAVIKEAFDSTSRFARLQKLQMSVAGRNLYIRFQSRSGDAMGMNMISKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAVNWIEGRGKSVVCEAVIPAKVVREVLKTTTEAMVEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTSLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMIHNRSKINLQDL 878
BLAST of EMLSAG00000004979 vs. GO
Match: - (symbol:HMGCR "3-hydroxy-3-methylglutaryl-coenzyme A reductase" species:9823 "Sus scrofa" [GO:0004420 "hydroxymethylglutaryl-CoA reductase (NADPH) activity" evidence=IEA] [GO:0005789 "endoplasmic reticulum membrane" evidence=IEA] [GO:0006695 "cholesterol biosynthetic process" evidence=IEA] [GO:0008299 "isoprenoid biosynthetic process" evidence=IEA] [GO:0015936 "coenzyme A metabolic process" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0050661 "NADP binding" evidence=IEA] UniPathway:UPA00058 InterPro:IPR000731 InterPro:IPR002202 InterPro:IPR004554 InterPro:IPR004816 InterPro:IPR009023 InterPro:IPR009029 InterPro:IPR023074 InterPro:IPR023076 InterPro:IPR023282 Pfam:PF00368 PRINTS:PR00071 PROSITE:PS00066 PROSITE:PS00318 PROSITE:PS01192 PROSITE:PS50065 PROSITE:PS50156 GO:GO:0016021 GO:GO:0005789 GO:GO:0050661 GO:GO:0006695 GO:GO:0015936 GO:GO:0008299 eggNOG:COG1257 KO:K00021 GO:GO:0004420 Gene3D:1.10.3270.10 Gene3D:3.30.70.420 Gene3D:3.90.770.10 PANTHER:PTHR10572 SUPFAM:SSF55035 SUPFAM:SSF56542 TIGRFAMs:TIGR00533 HOGENOM:HOG000183489 CTD:3156 HOVERGEN:HBG000453 TIGRFAMs:TIGR00920 EMBL:DQ531631 EMBL:DQ432054 RefSeq:NP_001116460.1 UniGene:Ssc.97427 ProteinModelPortal:Q1W675 SMR:Q1W675 STRING:9823.ENSSSCP00000014973 GeneID:100144446 KEGG:ssc:100144446 Uniprot:Q1W675) HSP 1 Score: 602.053 bits (1551), Expect = 0.000e+0 Identity = 349/910 (38.35%), Postives = 513/910 (56.37%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTFVPLDGGS---------PEWSP-------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY----AFLLSMTAF------LLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLI-TSPQGQAKWNVK---RILETLPTQEPPSRTPLRVLAFPVLVLLHL--TCLQPPSLQLHIQNTPHIIISL----------SLVLLSYYF-------------------------YSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSR----LKDDL------DRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLK-DQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAVGKL 841
G PWEV+ ++T + +++ G P++ +++ + R +++L +Y Q + + +LGS +L +AGL+ +F+ S L G +A LLL D+ + + L ++ALS+ + + + ++R M L PT D L++ L+ + L ++ ++L FVF +P +S+ L L S +G+ W + R+LE + P ++++ LVL+H + PS Q + + + L S+ L +Y + + E ++L L+ + + D R +++D + A + + + + K + +D VVG+ + S E+ P+++ E + EECL + + E + LS D E++ LV +HI ++ LE ++ H RGV +RR+L+S++ + + LPY+ ++Y VMGACCE+V+GYMP+PVG+ GPL LD K + +PMATTEGCLVASTNRGC A+ GG +S+I DGM+ PVVRFP + + K WLE P + IK++FDSTSRFARL KL++ +AGR +Y+RF +++GDAMGMNM+SK TE AL+KLH FPEMQI+++SGN CTDKKPAAVNWIEGRGKSVVCEA++PA +V +LKT+T A+V++N KN GSAMAGSIGG+NAH+ANIVTAI+IA GQDAAQN+GSSNC+TLME GP +DLYI+CTMPSIE+GT+GGGT L PQ +CL+MLGV+G +PGEN+RQLARI+CG V+AGELSLM+ALAAG LV SH+ HNRS + + L
Sbjct: 10 GLFVASHPWEVIVGTVTLTICMMSMNMFTGNDKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLATYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEGEENKPNPVTQRVKIIMSLGLVLVHAHSRWIADPSPQNSTADNSKVSLGLDENVSKRIEPSVSLWQFYLSKMISMDIEQVITLTLALLLAVKYIFFEQAETESTLSLKNPITSPVVTQKKVTDDCCRREPTLVRNDQKFHTVEEEARINRERKVEVIKPLVAETDTSSRPTFVVGNSTLDSSLELEMQEPEIQIPSEPRPNEECLQILGNAEKGAKFLS----------------------------------------DAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSKKLPE-PSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRILADGMT--PVVRFPRACDSAEVKAWLETPEGFAVIKEAFDSTSRFARLQKLQMSVAGRNLYIRFQSRSGDAMGMNMISKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAVNWIEGRGKSVVCEAVIPAKVVREVLKTTTEAMVEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTSLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMIHNRSKINLQDL 876
BLAST of EMLSAG00000004979 vs. GO
Match: - (symbol:HMGCR "Uncharacterized protein" species:9615 "Canis lupus familiaris" [GO:0004420 "hydroxymethylglutaryl-CoA reductase (NADPH) activity" evidence=IEA] [GO:0005778 "peroxisomal membrane" evidence=IEA] [GO:0005789 "endoplasmic reticulum membrane" evidence=IEA] [GO:0006695 "cholesterol biosynthetic process" evidence=IEA] [GO:0008299 "isoprenoid biosynthetic process" evidence=IEA] [GO:0008542 "visual learning" evidence=IEA] [GO:0009790 "embryo development" evidence=IEA] [GO:0015936 "coenzyme A metabolic process" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0043407 "negative regulation of MAP kinase activity" evidence=IEA] [GO:0051262 "protein tetramerization" evidence=IEA] [GO:0070402 "NADPH binding" evidence=IEA] InterPro:IPR000731 InterPro:IPR002202 InterPro:IPR004554 InterPro:IPR004816 InterPro:IPR009023 InterPro:IPR009029 InterPro:IPR023074 InterPro:IPR023076 InterPro:IPR023282 Pfam:PF00368 PRINTS:PR00071 PROSITE:PS00066 PROSITE:PS00318 PROSITE:PS01192 PROSITE:PS50065 PROSITE:PS50156 GO:GO:0016021 GO:GO:0051262 GO:GO:0005789 GO:GO:0008542 GO:GO:0006695 GO:GO:0005778 GO:GO:0009790 GO:GO:0015936 GO:GO:0043407 GO:GO:0070402 GO:GO:0008299 KO:K00021 GO:GO:0004420 Gene3D:1.10.3270.10 Gene3D:3.30.70.420 Gene3D:3.90.770.10 PANTHER:PTHR10572 SUPFAM:SSF55035 SUPFAM:SSF56542 TIGRFAMs:TIGR00533 GeneTree:ENSGT00390000006426 OMA:PNEECLQ OrthoDB:EOG7GXP9T TreeFam:TF105362 TIGRFAMs:TIGR00920 EMBL:AAEX03002157 RefSeq:XP_536323.3 Ensembl:ENSCAFT00000015129 GeneID:479182 NextBio:20854399 Uniprot:E2R9Z3) HSP 1 Score: 594.349 bits (1531), Expect = 0.000e+0 Identity = 348/911 (38.20%), Postives = 511/911 (56.09%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTFVPLDGGS---------PEWSP-------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY----AFLLSMTAF------LLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLI-TSPQGQAKWNVK---RILETLPTQEPPSRTPLRVLAFPVLVLLHLTC--LQPPSLQLHIQNTPH-----------------------------------IIISLSLVLLSYYFYSNKDEDATSLHLRKSYEEAFT--RKLQD----QDSSVSRLKDDLDRASQST----DEGIGLTKSANSASDLKKSKILVVGDDSSSESAWS-EVYMPDLK-DQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAVGKL 841
G PWEV+ ++T + +++ G P++ +++ + R +++L +Y Q + + +LGS +L +AGL+ +F+ S L G +A LLL D+ + + L ++ALS+ + + + ++R M L PT D L++ L+ + L ++ ++L FVF +P +S+ L L S +G+ W + R+LE + P ++++ LVL+H + PS Q + + L+L+L Y + + E ++L L+ +K+ D ++ + R + A + T + + + K + +D VVG+ S +++ E P+++ E + EECL + + E + LS D L++ H I ++ LE ++ H RGV +RR+L+SR+ + + LPY+ ++Y VMGACCE+V+GYMP+PVG+ GPL LD K + +PMATTEGCLVASTNRGC A+ GG +S+I DGM+RGPVVR P + + K WLE P + IK++FDSTSRFARL KL + +AGR +Y+RF +++GDAMGMNM+SK TE AL+KLH FPEMQI+++SGN CTDKKPAA+NWIEGRGKSVVCEA++PA +V +LKT+T A++++N KN GSAMAGSIGG+NAH+ANIVTAI+IA GQDAAQN+GSSNC+TLME GP +DLYI+CTMPSIE+GT+GGGT L PQ +CL+MLGV+G +PGEN+RQLARI+CG V+AGELSLM+ALAAG LV SH+ HNRS + + L
Sbjct: 26 GLFVASHPWEVIVGTVTLTICMMSMNMFTGNDKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTSENSRVSLGLDENVSKRIEPSVSLWQFYLSKMISMDIEQVVTLGLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKVPDDCCRREPVLVRNSHKVHAAEEETRINRERKVEVIKPFVAETDTSSRATFVVGNSSLLDTSVELETQEPEIELPMEPRPNEECLQILGNAEKGAKFLS-DAEIIQLVNAKH---------------------------------------IPAYKLETLMETHERGVSIRRQLLSRKLPE-PSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRILADGMTRGPVVRLPRACDSAEVKAWLETPEGFTVIKEAFDSTSRFARLQKLHMSMAGRNLYIRFQSRSGDAMGMNMISKGTEKALSKLHEHFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREVLKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDL 895
BLAST of EMLSAG00000004979 vs. C. finmarchicus
Match: gi|592906562|gb|GAXK01051813.1| (TSA: Calanus finmarchicus comp28195_c1_seq1 transcribed RNA sequence) HSP 1 Score: 650.588 bits (1677), Expect = 0.000e+0 Identity = 405/858 (47.20%), Postives = 551/858 (64.22%), Query Frame = 0
Query: 69 YVQLKRIHRLGSAVLLHVA-GLYAF---LLSMTAFLLGGPD------AAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQXXXXXXXXXXXXXX--------XXXXXXXXXXXXXXXXXXXXXXXXXXXYPPLLSIALXLITSPQGQAKWNVKRILETLPTQE--PPSRTPLRVLAFPVLVLLHLTCLQPPS-----------------LQLHIQNTPHXXXXXXXXXXXXXXXXNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSRLKD--------------DLDRASQSTDEGIGLT---------------------KSANSASDLKKSKILVVG-----DDSSSESAWSEVYMP-DLKDQEA--QTTEECLVVSSSDEDRDETXXXXXXXXXXXXXXXXXPPRSIERCLLILKENAQRNEPCPXXXXXXXXXXXXRHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVXXXXXXXXXXXXXXXXXXXXXRHNRSTLAVGKLAEITE 846
Y K++HR+GS++++ + G +F L S+ F L GP+ + F ++L +DIPK+T++ Q+AL+++H +P ++ M L P + ++T+ K+ + L LL + V +++ +F +P LS+ + L+ + G+ +W+VK+I+++LPT+E P +RV+A LV +H C P L+L + N I L ++ L+ + +D + + +RK+Y E RK + S S D ++DR+S STDEGI L+ + + S + L + VG D+ SESAWSEVYM D++ +E QT V DE+ + E PR + CL ++ N+ + L D EVV LVE++H+ H LEK + D RGV +RRK I + +L++A E LPY+H+DY V+GACCE+V+GYMPVPVG+VGPL LD + HIPMATTEGCLVASTNRGC AL CG VT+ +T DGM+RGPVVRFP ++ A A W+++ N++ IK FDSTSRFARL +L +R AGR +Y+RFVA++GDAMGMNMLSKATEFA+N++ +FP+M+++S+SGN CTDKKPAAVNW+EGRGKSVV EAIVPA IV T+LKTST+ALVDLN +KN GS+MAGSIGGFNAH+ANI+TAI+IATGQDAAQN+GSSNC+TLMEPWG G+DLY+TC+MPSIEVGT+GGGT+L Q SCLEMLGVKGPHPT PGEN+ QLARI+CG+VLAGELSLMSALAAG LV SHL+HNRST G L+++ E
Sbjct: 711 YYHFKKVHRVGSSLIMKITLGYLSFTMLLYSLVVFGLIGPEFDNVKESWFLIMLFTDIPKVTRMAQFALTSSHHKRIPANVAVGMAQLGPAMTFETVGKVLLVGLCGLTNYKRLELLATYAVITVVVDFLIFMSFFPAGLSLVIELMFTKAGRPQWDVKQIIKSLPTEEIQNPVVYRVRVIAMTGLVTVHTLCRWPVDHAVAGSARAASYISSEWLKLVVANAEQFGILLVVLALAVKYLFYEDWEE-NFRIRKTYLEELERKFDEASESDSVSVDTNTSERSTLRPHTHEMDRSSNSTDEGISLSTISQRRMSATFERRMSSSLERRLSGSKTHLGHRAVDRVGLSLGQCDTCSESAWSEVYMNNDMESKEVGIQTNFTDSGVEKIDEEESDKEFEQV-------------PRDVSECLRVM--NSSPDGIKQLVDSEVVELVEKKHMAGHQLEKAVGDPSRGVRIRRK-IYGKHGNLKRAMENLPYQHYDYQKVLGACCENVIGYMPVPVGVVGPLNLDGRSLHIPMATTEGCLVASTNRGCRALQGCG-VTTAVTYDGMTRGPVVRFPCMTRATDAMKWMDNKSNFESIKAHFDSTSRFARLQRLHIRCAGRSLYIRFVARSGDAMGMNMLSKATEFAINRMLDVFPDMEVVSLSGNFCTDKKPAAVNWVEGRGKSVVAEAIVPAHIVRTVLKTSTSALVDLNISKNLVGSSMAGSIGGFNAHAANIITAIYIATGQDAAQNVGSSNCITLMEPWGEHGEDLYMTCSMPSIEVGTVGGGTVLPAQSSCLEMLGVKGPHPTMPGENASQLARIVCGSVLAGELSLMSALAAGHLVRSHLKHNRST--PGNLSKLGE 3224
BLAST of EMLSAG00000004979 vs. C. finmarchicus
Match: gi|592880301|gb|GAXK01077600.1| (TSA: Calanus finmarchicus comp6419389_c0_seq1 transcribed RNA sequence) HSP 1 Score: 34.2686 bits (77), Expect = 1.025e+0 Identity = 21/53 (39.62%), Postives = 31/53 (58.49%), Query Frame = 0
Query: 567 AKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAK--TGDAM 617
AK+WL DP + K+SFD ++NK V +AG + +RF+A TGD +
Sbjct: 251 AKEWLSDPSWVKVFKNSFDVLED--QINKGLVAVAGFALAVRFLANLPTGDLL 403
BLAST of EMLSAG00000004979 vs. C. finmarchicus
Match: gi|592890694|gb|GAXK01067681.1| (TSA: Calanus finmarchicus comp16755_c2_seq1 transcribed RNA sequence) HSP 1 Score: 32.7278 bits (73), Expect = 6.163e+0 Identity = 35/149 (23.49%), Postives = 57/149 (38.26%), Query Frame = 0
Query: 518 ATTEGCLVASTNRGCSALSKCGGVTSQITDDG---MSRGPV-------VRFPNVSAAKKAKDWLEDPVN-YQEIK-----DSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTG-DAMGMNMLSKATEFALNKLHFIFPEMQIISISGNM 649
A GCLV + GGV S + DG M G V + A A W+E+ + + +IK D + R L+ ++ L G + ++ A+ D G +L A A N++ + + + I NM
Sbjct: 501 AQEAGCLVTGGQTVLNPWVTIGGVASTVCSDGDIIMPEGAVDGDVLLLTKALGTQVAVNAHQWMEEEGDRWDKIKNLTTMDEVKAAYRATTLSMARLNLTGAKLMHKYKARAATDVTGFGILGHAKNLAENQIKPVDFTIHTLPIISNM 947
BLAST of EMLSAG00000004979 vs. L. salmonis peptides
Match: EMLSAP00000004979 (pep:novel supercontig:LSalAtl2s:LSalAtl2s260:1508384:1510927:-1 gene:EMLSAG00000004979 transcript:EMLSAT00000004979 description:"augustus_masked-LSalAtl2s260-processed-gene-14.5") HSP 1 Score: 1732.23 bits (4485), Expect = 0.000e+0 Identity = 847/847 (100.00%), Postives = 847/847 (100.00%), Query Frame = 0
Query: 1 MXRRPPLKFLEDVSDCLGQATVKQPWEVLFVSLTSLLSLVTFVPLDGGSPEWSPVVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLYAFLLSMTAFLLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTLLPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLITSPQGQAKWNVKRILETLPTQEPPSRTPLRVLAFPVLVLLHLTCLQPPSLQLHIQNTPHIIISLSLVLLSYYFYSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSRLKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAVGKLAEITEN 847
MXRRPPLKFLEDVSDCLGQATVKQPWEVLFVSLTSLLSLVTFVPLDGGSPEWSPVVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLYAFLLSMTAFLLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTLLPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLITSPQGQAKWNVKRILETLPTQEPPSRTPLRVLAFPVLVLLHLTCLQPPSLQLHIQNTPHIIISLSLVLLSYYFYSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSRLKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAVGKLAEITEN
Sbjct: 1 MXRRPPLKFLEDVSDCLGQATVKQPWEVLFVSLTSLLSLVTFVPLDGGSPEWSPVVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLYAFLLSMTAFLLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTLLPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLITSPQGQAKWNVKRILETLPTQEPPSRTPLRVLAFPVLVLLHLTCLQPPSLQLHIQNTPHIIISLSLVLLSYYFYSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSRLKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAVGKLAEITEN 847
BLAST of EMLSAG00000004979 vs. SwissProt
Match: gi|1708251|sp|P54960.1|HMDH_BLAGE (RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase; Short=HMG-CoA reductase) HSP 1 Score: 646.351 bits (1666), Expect = 0.000e+0 Identity = 390/886 (44.02%), Postives = 533/886 (60.16%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTF--VPLDGGSPEWSP-------------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLYA-------------FLLSMTAFLLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLITSPQ-GQAKWNVKRILETLPTQEPPSRTPL----RVLAFPVLVLLH----LTCLQPPSLQLHIQNTPHIIISLSLVLLSYYFYSNKDEDATSLHLRKSY----EEAFTRKLQDQDSSVSRLKDDLDRASQSTDEGI-------GLTKSAN-------SASDLKKSKILVVGDDSSSE---SAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLA 837
GQ PWEV+ +LT + ++T PL G P W +V+ + R +++L Y Q + +LGS +L +AGL+ FL S + L DA F LLL D+ K T L Q+ALS+ + + ++R + L PT+ DT+++ L+ + L +L ++++ VF YP LS+ L L S + G+ W+ K ++ +E P+ +V+ L+L+H + CL I+L L S ++ + S + R S+ EE T KL DS V+ S STD+ LT SA+ + K D+ ++ W EV P ++ + QT + S ++ L E +S+ RSI+ CL + K + L+D EV+ LV HI + LEKV+ + RGV +RR+++++ L+ A + LPYK++DY VMGACCE+V+GYMPVPVG+ GPL LD +L H+P+ATTEGCLVASTNRG AL +CG VTS+I DGM+RGPVVRFPN+ A +A W++ P N+++IK +FDSTSRFARL+K+ +R+AGR +++RF+A TGDAMGMNMLSK TE AL + ++P+M+I+S+SGN CTDKKPAAVNWIEGRGKSVVCEAIVPA I++++LKTS AL+D+N KN GSA+AGSIGGFNAH+ANIVTAIFIATGQD AQN+GSSNCMTLMEPWG DGKDLY++CTMPSIE+GTIGGGT+L PQ +CL+MLGV+G + PGEN+ LARI+CG VLAGELSLMSALAAG LV SH+RHNRS+++
Sbjct: 10 GQFCASHPWEVIVATLTLTVCMLTVDQRPL-GLPPGWGHNCITLEEYNAADMIVMTLIRCVAVLYSYYQFCHLQKLGSKYILGIAGLFTVFSSFVFSSSVINFLGSDVSDL---KDALFFFLLLIDLSKATVLAQFALSSRSQDEVKHNIARGIAMLGPTITLDTVVETLVIGVGMLSGVRRLEVLCCFACMSVIVNYVVFMTFYPACLSLILELSRSGESGRPAWHDKSLIIKALHEEDQKPNPVVQRVKVIMSAGLMLVHAHRWVRCLS---------------IALWPDLTSLRYFCTHCDTGVS-YSRWSFASEGEELPTVKLVTGDSVVN---------SNSTDDAQLHYYIMRWLTVSADHIVILILLLALAVKFVFFETRDELTTTRGMDGWVEVSSP-VEHKYVQTEQP------SCSAPEQPLEEPPASN-----------RSIDECLSVCKSDVGAQA---LSDCEVMALVTSGHIAGYQLEKVVRNPERGVGIRRQILTKTAD-LKDALDNLPYKNYDYLKVMGACCENVIGYMPVPVGVAGPLNLDGRLVHVPLATTEGCLVASTNRGMRALMRCG-VTSRIVADGMTRGPVVRFPNIDRASEAMLWMQVPYNFEQIKKNFDSTSRFARLSKIHIRVAGRHLFIRFIATTGDAMGMNMLSKGTEVALAYVQQVYPDMEILSLSGNFCTDKKPAAVNWIEGRGKSVVCEAIVPADIIKSVLKTSVQALMDVNITKNLIGSAVAGSIGGFNAHAANIVTAIFIATGQDPAQNVGSSNCMTLMEPWGEDGKDLYVSCTMPSIEIGTIGGGTVLPPQAACLDMLGVRGANEMCPGENANTLARIVCGTVLAGELSLMSALAAGHLVKSHMRHNRSSVS 843
BLAST of EMLSAG00000004979 vs. SwissProt
Match: gi|123341|sp|P00347.1|HMDH_CRIGR (RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase; Short=HMG-CoA reductase) HSP 1 Score: 618.616 bits (1594), Expect = 0.000e+0 Identity = 365/886 (41.20%), Postives = 523/886 (59.03%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTFVPLDGGS---------PEWSP-------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY----AFLLSMTAF------LLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLI-TSPQGQAKWNVK---RILETLPTQEPPSRTPLRVLAFPVLVLLHL--TCLQPPSLQLHIQNTPHIIISL------------SLVLLSYYF---YSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSRLKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDL-KDQEAQTTEECLVVSSSDEDRDETLSEDGSS------SHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAVGKL 841
G PWEV+ ++T + +++ G + P++ +++ + R +++L +Y Q + + +LGS +L +AGL+ +F+ S L G +A LLL D+ + + L ++ALS+ + + + ++R M L PT D L++ L+ + L ++ ++L FVF +P +S+ L L S +G+ W + R+LE + P ++++ LVL+H + PS Q T H +SL S+ L +Y S E +L L + Q + S LK+ + T + K+ ++ ++ +LV SE S P + +D++ + + +V + S L G+S + L + S PR E CL IL E+A++ L+D E++ LV +HI ++ LE ++ H RGV +RR+L+S + + + LPY+ ++Y VMGACCE+V+GYMP+PVG+ GPL LD K Y +PMATTEGCLVASTNRGC A+ GG +S++ DGM+RGPVVR P + + K WLE P + IKD+FDSTSRFARL KL V +AGR +Y+RF +KTGDAMGMNM+SK TE AL KL FPEMQI+++SGN CTDKKPAA+NWIEGRGK+VVCEA++PA +V +LKT+T A++D+N KN GSAMAGSIGG+NAH+ANIVTAI+IA GQDAAQN+GSSNC+TLME GP +DLYI+CTMPSIE+GT+GGGT L PQ +CL+MLGV+G +PGEN+RQLARI+CG V+AGELSLM+ALAAG LV SH+ HNRS + + L
Sbjct: 10 GLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQ--NSTTEHSKVSLGLDEDVSKRIEPSVSLWQFYLSKMISMDIEQVVTLSLAFLLAVKYIFFEQAETESTLSLKNPI------TSPVVTPKKAPDNCC--RREPLLV----RRSEKLSSVEEEPGVSQDRKVEVIKPLVVETESASRATFVLGASGTSPPVAARTQELEIELPSEPRPNEECLQIL-ESAEKGAKF-LSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSTKLPE-PSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRACDSAEVKAWLETPEGFAVIKDAFDSTSRFARLQKLHVTMAGRNLYIRFQSKTGDAMGMNMISKGTEKALLKLQEFFPEMQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMIDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDL 878
BLAST of EMLSAG00000004979 vs. SwissProt
Match: gi|408360266|sp|Q01237.3|HMDH_MOUSE (RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase; Short=HMG-CoA reductase) HSP 1 Score: 617.461 bits (1591), Expect = 0.000e+0 Identity = 359/903 (39.76%), Postives = 517/903 (57.25%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTFVPLDGGS---------PEWSP-------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY----AFLLSMTAF------LLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLI-TSPQGQAKWNVK---RILETLPTQEPPSRTPLRVLAFPVLVLLHL--TCLQPPSLQ-----------------------------------LHIQNTPHIIISLSLVLLSYYFYSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSR----LKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAVGKL 841
G PWEV+ ++T + +++ G + P++ +++ + R +++L +Y Q + + +LGS +L +AGL+ +F+ S L G +A LLL D+ + + L ++ALS+ + + + ++R M L PT D L++ L+ + L ++ ++L FVF +P +S+ L L S +G+ W + R+LE + P ++++ LVL+H + PS Q + + I +SL+ +L Y + + E ++L L+ + QD+ R ++ + +S D G AN ++ K LVV +++S + + V+ +S L L PR E CL IL ENA++ L+D E++ LV +HI ++ LE ++ H RGV +RR+L+S + + + LPY+ ++Y VMGACCE+V+GYMP+PVG+ GPL LD K Y +PMATTEGCLVASTNRGC A+S GG +S++ DGM+RGPVVR P + + K WLE P + IK++FDSTSRFARL KL V +AGR +Y+RF ++TGDAMGMNM+SK TE AL KL FP+MQI+++SGN CTDKKPAA+NWIEGRGK+VVCEA++PA +V +LKT+T A+VD+N KN GSAMAGSIGG+NAH+ANIVTAI+IA GQDAAQN+GSSNC+TLME GP +DLYI+CTMPSIE+GT+GGGT L PQ +CL+MLGV+G +PGEN+RQLARI+CG V+AGELSLM+ALAAG LV SH+ HNRS + + L
Sbjct: 10 GLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQAKVSLGLDEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLAFLLAVKYIFFEQAETESTLSLKNPITSPVVTSKKAQDNCCRREPLLVRRNQKLSSVEEDPG------ANQERKVEVIKPLVVEAETTSRATF--------------------VLGASVASPPSALGTQEPGIEL-----PIEPRPNEECLQIL-ENAEKGAKF-LSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSTKLAE-PSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMTRGPVVRLPRACDSAEVKTWLETPEGFAVIKEAFDSTSRFARLQKLHVTMAGRNLYIRFQSRTGDAMGMNMISKGTEKALLKLQEFFPDMQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDL 878
BLAST of EMLSAG00000004979 vs. SwissProt
Match: gi|2495262|sp|Q29512.1|HMDH_RABIT (RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase; Short=HMG-CoA reductase) HSP 1 Score: 616.305 bits (1588), Expect = 0.000e+0 Identity = 356/909 (39.16%), Postives = 519/909 (57.10%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTFVPLDGGS---------PEWSP-------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY----AFLLSMTAF------LLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLI-TSPQGQAKWNVK---RILETLPTQEPPSRTPLRVLAFPVLVLLHL--TCLQPPSLQLHIQNTPH-----------------------------------IIISLSLVLLSYYFYSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSR----LKDDL------DRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAVGKL 841
G PWEV+ ++T + +++ G P++ +++ + R +++L +Y Q + + +LGS +L +AGL+ +F+ S L G +A LLL D+ + + L ++ALS+ + + + ++R M L PT D L++ L+ + L ++ ++L FVF +P +S+ L L S +G+ W + R+LE + P ++++ LVL+H + PS Q + I +SL+L+L Y + + E ++L L+ + + DS R ++++ + A S D + + K + +D VVG S +++ + + K+ E + +E PR E CL IL NA++ L+D E++ LV +HI ++ LE ++ H RGV +RR+L+S++ + + LPY+ ++Y V+GACCE+V+GYMP+PVG+VGPL LD K + +PMATTEGCLVASTNRGC A+ GG +S++ DGM+RGPVVR P + + K WLE P + IK++FDSTSRFARL KL + +AGR +Y+RF ++TGDAMGMNM+SK TE AL+KLH FPEMQI+++SGN CTDKKPAAVNWIEGRGK+VVCEA++PA +V +LKT+T A++D+N KN GSAMAGSIGG+NAH+AN VTAI+IA GQDAAQN+GSSNC+TLME GP +DLYI+CTMPSIE+GT+GGGT L PQ +CL+MLGV+G SPGEN+RQLARI+CG V+AGELSLM+ALAAG LV SH+ HNRS + + L
Sbjct: 10 GLFVASHPWEVIVGTVTLTICMMSMNMFTGNDKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADNSKVSLGLDENVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTQKKVPDSCCRREPVVVRNNQKFCSVEEEAGMSQDRKVEVIKPLVAETDSPHRAAFVVGGSSFPDTS----LVLETKEPEIELPKE--------------------------------PRPNEECLQILG-NAEKGAKF-LSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSKKLPE-PSSLQYLPYRDYNYSLVLGACCENVIGYMPIPVGVVGPLCLDGKEFQVPMATTEGCLVASTNRGCRAICLGGGASSRVLADGMTRGPVVRLPRACDSAEVKAWLETPEGFAVIKEAFDSTSRFARLQKLHISMAGRNLYIRFQSRTGDAMGMNMISKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAVNWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMIDVNINKNLVGSAMAGSIGGYNAHAANYVTAIYIACGQDAAQNVGSSNCITLMEASGPPNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDSPGENARQLARIVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDL 879
BLAST of EMLSAG00000004979 vs. SwissProt
Match: gi|123344|sp|P09610.1|HMDH_MESAU (RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase; Short=HMG-CoA reductase) HSP 1 Score: 615.535 bits (1586), Expect = 0.000e+0 Identity = 363/886 (40.97%), Postives = 517/886 (58.35%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTFVPLDGGS---------PEWSP-------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY----AFLLSMTAF------LLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLI-TSPQGQAKWNVK---RILETLPTQEPPSRTPLRVLAFPVLVLL--HLTCLQPPSLQLHIQNTPHIIISL------------SLVLLSYYF---YSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSRLKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSS-SESAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHH------SPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAVGKL 841
G PWEV+ ++T + +++ G + P++ +++ + R +++L +Y Q + + +LGS +L +AGL+ +F+ S L G +A LLL D+ + + L ++ALS+ + + + ++R M L PT D L++ L+ + L ++ ++L FVF +P +S+ L L S +G+ W + R+LE + P ++++ LVL+ H + PS Q T H +SL S+ L +Y S E +L L + Q + S LK+ + + + + K+ V ++ ++ EV P + + E+ T+ V+ +S G S + G S PR E CL IL E+A++ L+D E++ LV +HI ++ LE ++ H RGV +RR+L+S + + + LPY+ ++Y VMGACCE+V+GYMP+PVG+ GPL LD K Y +PMATTEGCLVASTNRGC A+ GG +S++ DGM+RGPVVR P + + K WLE P + IKD+FDSTSRFARL KL V +AGR +Y+RF +KTGDAMGMNM+SK TE AL KL FPEMQI+++SGN CTDKKPAAVNWIEGRGK+VVCEA++PA +V +LKT+T A++D+N KN GSAMAGSIGG+NAH+ANIVTAI+IA GQDAAQN+GSSNC+TLME GP +DLYI+CTMPSIE+GT+GGGT L PQ +CL+MLGV+G +PGEN+RQLARI+CG V+AGELSLM+ALAAG LV SH+ HNRS + + L
Sbjct: 10 GLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQ--NSTTEHSKVSLGLDEDVSKRIEPSVSLWQFYLSKMISMDIEQVVTLSLAFLLAVKYIFFEQAETESTLSLKNPITSPVATPKKAPDNCCRREPVLSRRNEKLSSVEEEPGVNQDRKVEVIKPLVAETES-TSRATFVLGAS-----------GGCSPVALGTQEPEIELPSEPRPNEECLQIL-ESAEKGAKF-LSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSTKLPE-PSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRACDSAEVKAWLETPEGFAVIKDAFDSTSRFARLQKLHVTMAGRNLYIRFQSKTGDAMGMNMISKGTEKALVKLQEFFPEMQILAVSGNYCTDKKPAAVNWIEGRGKTVVCEAVIPARVVREVLKTTTEAMIDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDL 878
BLAST of EMLSAG00000004979 vs. SwissProt
Match: gi|123343|sp|P04035.1|HMDH_HUMAN (RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase; Short=HMG-CoA reductase) HSP 1 Score: 614.379 bits (1583), Expect = 0.000e+0 Identity = 355/899 (39.49%), Postives = 516/899 (57.40%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTFVPLDGGS---------PEWSP-------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY----AFLLSMTAF------LLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLI-TSPQGQAKWNVK---RILETLPTQEPPSRTPLRVLAFPVLVLLHL--TCLQPPSLQLHIQNTPH-----------------------------------IIISLSLVLLSYYFYSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSRLKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAVGKL 841
G PWEV+ ++T + +++ G + P++ +++ + R +++L +Y Q + + +LGS +L +AGL+ +F+ S L G +A LLL D+ + + L ++ALS+ + + + ++R M L PT D L++ L+ + L ++ ++L FVF +P +S+ L L S +G+ W + R+LE + P ++++ LVL+H + PS Q +T I +SL+L+L Y + + E ++L L+ + + D+ R + L R +Q D S + + + + + EV P + + + +V +SS D L L PR E CL IL NA++ L+D E++ LV +HI ++ LE ++ H RGV +RR+L+S++ + + LPY+ ++Y VMGACCE+V+GYMP+PVG+ GPL LD K + +PMATTEGCLVASTNRGC A+ GG +S++ DGM+RGPVVR P + + K WLE + IK++FDSTSRFARL KL +AGR +Y+RF +++GDAMGMNM+SK TE AL+KLH FPEMQI+++SGN CTDKKPAA+NWIEGRGKSVVCEA++PA +V +LKT+T A++++N KN GSAMAGSIGG+NAH+ANIVTAI+IA GQDAAQN+GSSNC+TLME GP +DLYI+CTMPSIE+GT+GGGT L PQ +CL+MLGV+G +PGEN+RQLARI+CG V+AGELSLM+ALAAG LV SH+ HNRS + + L
Sbjct: 10 GLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSLKNPITSPVVTQKKVPDNCCRR-EPMLVRNNQKCD-------SVEEETGINRERKV-------------EVIKPLVAETDTPNRATFVVGNSSLLDTSSVLVTQEPEIEL-----PREPRPNEECLQILG-NAEKGAKF-LSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSKKLSE-PSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDEKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRACDSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSRSGDAMGMNMISKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREVLKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDL 879
BLAST of EMLSAG00000004979 vs. SwissProt
Match: gi|118573791|sp|P51639.2|HMDH_RAT (RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase; Short=HMG-CoA reductase) HSP 1 Score: 613.609 bits (1581), Expect = 0.000e+0 Identity = 358/904 (39.60%), Postives = 513/904 (56.75%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTFVPLDGGS---------PEWSP-------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY----AFLLSMTAF------LLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLI-TSPQGQAKWNVK---RILETLPTQEPPSRTPLRVLAFPVLVLL--HLTCLQPPSLQ-----------------------------------LHIQNTPHIIISLSLVLLSYYFYSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSR----LKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHH------SPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTL 836
G PWEV+ ++T + +++ G + P++ +++ + R +++L +Y Q + + +LGS +L +AGL+ +F+ S L G +A LLL D+ + + L ++ALS+ + + + ++R M L PT D L++ L+ + L ++ ++L FVF +P +S+ L L S +G+ W + R+LE + P ++++ LVL+ H + PS Q + + I +SL+L+L Y + + E ++L L+ + QD+ R ++ + +S D G+ N ++ K LV ++S + + L +S L G S PR E CL IL E+A++ L+D E++ LV +HI ++ LE ++ H RGV +RR+L+S + + + LPY+ ++Y VMGACCE+V+GYMP+PVG+ GPL LD K Y +PMATTEGCLVASTNRGC A+S GG +S++ DGMSRGPVVR P + + K WLE P + +K++FDSTSRFARL KL V LAGR +Y+R +KTGDAMGMNM+SK TE AL KL FPE+QI+++SGN CTDKKPAA+NWIEGRGK+VVCEA++PA +V +LKT+T A+VD+N KN GSAMAGSIGG+NAH+ANIVTAI+IA GQDAAQN+GSSNC+TLME GP +DLYI+CTMPSIE+GT+GGGT L PQ +CL+MLGV+G +PGEN+RQLARI+CG V+AGELSLM+ALAAG LV SH+ HNRS +
Sbjct: 10 GLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGV------NQDRKVEVIKPLVAEAETSGRATF-------------------------------VLGASAASPPLALGAQEPGIELPSEPRPNEECLQIL-ESAEKGAKF-LSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAE-PSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKI 873
BLAST of EMLSAG00000004979 vs. SwissProt
Match: gi|391359371|sp|A7Z064.2|HMDH_BOVIN (RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase; Short=HMG-CoA reductase) HSP 1 Score: 612.838 bits (1579), Expect = 0.000e+0 Identity = 357/887 (40.25%), Postives = 519/887 (58.51%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTFVPLDGGSP--EWSP--------------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY----AFLLSMTAF------LLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLI-TSPQGQAKWNVK---RILETLPTQEPPSRTPLRVLAFPVLVLL--HLTCLQPPSLQLHIQNTPHIIISL----------SLVLLSYYF---YSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSRLKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHL---LSGDHHSP-------PRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAVGKL 841
G PWEV+ ++T + +++ G + W+ +++ + R +++L +Y Q + + +LGS +L +AGL+ +F+ S L G +A LLL D+ + + L ++ALS+ + + + ++R M L PT D L++ L+ + L ++ ++L FVF +P +S+ L L S +G+ W + R+LE + P ++++ LVL+ H + PS Q + + + L S+ L +Y S E +L L + Q + S LK+ + + D + ++V +D + E K++E + +++ +D T G+SS L L + P PR E CL IL ENA++ L+D E++ LV +HI ++ LE ++ H RGV +RR+L+S++ + + LPY+ ++Y VMGACCE+V+GYMP+PVG+ GPL LD K + +PMATTEGCLVASTNRGC A+ GG +S++ DGM+RGPVVRFP + + K WLE P + IK++FDSTSRFARL KL + +AGR +Y+RF +++GDAMGMNM+SK TE AL+KL FPEMQI+++SGN CTDKKPAA+NWIEGRGKSVVCEA++PA +V +LKT+T A++++N KN GSAMAGSIGG+NAH+ANIVTAI+IA GQDAAQN+GSSNC+TLME GP +DLYI+CTMPSIE+GT+GGGT L PQ +CL+MLGV+G +PGEN+RQLARI+CG V+AGELSLM+ALAAG LV SH+ HNRS + + L
Sbjct: 10 GLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKLEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLVDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADNSKVSLGLDENVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSP---------VVTQKKITDDCCRRDPVLVRNDQKFHAMEEETR----KNRERKVEVIKPLLAENDTSHRATFVV-GNSSLLGTSLELETQEPEMELPVEPRPNEECLQIL-ENAEKGAKF-LSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSKKLPE-PSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRFPRACDSAEVKAWLETPEGFTVIKEAFDSTSRFARLQKLHMSVAGRNLYIRFQSRSGDAMGMNMISKGTEKALSKLQEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREVLKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACRDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMIHNRSKINLQDL 879
BLAST of EMLSAG00000004979 vs. SwissProt
Match: gi|83305798|sp|Q5R6N3.1|HMDH_PONAB (RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase; Short=HMG-CoA reductase) HSP 1 Score: 610.912 bits (1574), Expect = 0.000e+0 Identity = 354/899 (39.38%), Postives = 514/899 (57.17%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTFVPLDGGS---------PEWSP-------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY----AFLLSMTAF------LLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLI-TSPQGQAKW---NVKRILETLPTQEPPSRTPLRVLAFPVLVLLHL--TCLQPPSLQLHIQNTPH-----------------------------------IIISLSLVLLSYYFYSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSRLKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAVGKL 841
G PWEV+ ++T + +++ G + P++ +++ + R +++L +Y Q + + +LGS +L +AGL+ +F+ S L G +A LLL D+ + + L ++ALS+ + + + ++R M L PT D L++ L+ + L ++ ++L FVF +P +S+ L L S +G+ W + R+LE + P ++++ LVL+H + PS Q +T I +SL+L+L Y + + E ++L L+ + + D R + L R +Q D S + + + + + EV P + + + +V +SS D L L PR E CL IL NA++ L+D E++ LV +HI ++ LE ++ H RGV +RR+L+S++ + + LPY+ ++Y VMGACCE+V+GYMP+PVG+ GPL LD K + +PMATTEGCLVASTNRGC A+ GG +S++ DGM+RGPVVR P + + K WLE + IK++FDSTSRFARL KL +AGR +Y+RF +++GDAMGMNM+SK TE AL+KLH FPEMQI+++SGN CTDKKPAA+NWIEGRGKS VCEA++PA +V +LKT+T A++++N KN GSAMAGSIGG+NAH+ANIVTAI+IA GQDAAQN+GSSNC+TLME GP +DLYI+CTMPSIE+GT+GGGT L PQ +CL+MLGV+G +PGEN+RQLARI+CG V+AGELSLM+ALAAG LV SH+ HNRS + + L
Sbjct: 10 GLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWLLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSLKNPITSPVVTQKKVPDDCCRR-EPMLVRNNQKCD-------SVEEETGINRERKV-------------EVIKPLVAETDTPNRATFVVGNSSLLDTSSVLVTQEPEIEL-----PREPRPNEECLQILG-NAEKGAKF-LSDAEIIQLVIAKHIPAYKLETLMETHERGVSIRRQLLSKKLSE-PSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRACDSAEVKAWLETSEGFAVIKEAFDSTSRFARLRKLHTSIAGRNLYIRFQSRSGDAMGMNMISKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSAVCEAVIPAKVVREVLKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDL 879
BLAST of EMLSAG00000004979 vs. SwissProt
Match: gi|118573790|sp|Q1W675.1|HMDH_PIG (RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase; Short=HMG-CoA reductase) HSP 1 Score: 602.053 bits (1551), Expect = 0.000e+0 Identity = 349/910 (38.35%), Postives = 513/910 (56.37%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTFVPLDGGS---------PEWSP-------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY----AFLLSMTAF------LLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLI-TSPQGQAKWNVK---RILETLPTQEPPSRTPLRVLAFPVLVLLHL--TCLQPPSLQLHIQNTPHIIISL----------SLVLLSYYF-------------------------YSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSR----LKDDL------DRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLK-DQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAVGKL 841
G PWEV+ ++T + +++ G P++ +++ + R +++L +Y Q + + +LGS +L +AGL+ +F+ S L G +A LLL D+ + + L ++ALS+ + + + ++R M L PT D L++ L+ + L ++ ++L FVF +P +S+ L L S +G+ W + R+LE + P ++++ LVL+H + PS Q + + + L S+ L +Y + + E ++L L+ + + D R +++D + A + + + + K + +D VVG+ + S E+ P+++ E + EECL + + E + LS D E++ LV +HI ++ LE ++ H RGV +RR+L+S++ + + LPY+ ++Y VMGACCE+V+GYMP+PVG+ GPL LD K + +PMATTEGCLVASTNRGC A+ GG +S+I DGM+ PVVRFP + + K WLE P + IK++FDSTSRFARL KL++ +AGR +Y+RF +++GDAMGMNM+SK TE AL+KLH FPEMQI+++SGN CTDKKPAAVNWIEGRGKSVVCEA++PA +V +LKT+T A+V++N KN GSAMAGSIGG+NAH+ANIVTAI+IA GQDAAQN+GSSNC+TLME GP +DLYI+CTMPSIE+GT+GGGT L PQ +CL+MLGV+G +PGEN+RQLARI+CG V+AGELSLM+ALAAG LV SH+ HNRS + + L
Sbjct: 10 GLFVASHPWEVIVGTVTLTICMMSMNMFTGNDKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLATYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEGEENKPNPVTQRVKIIMSLGLVLVHAHSRWIADPSPQNSTADNSKVSLGLDENVSKRIEPSVSLWQFYLSKMISMDIEQVITLTLALLLAVKYIFFEQAETESTLSLKNPITSPVVTQKKVTDDCCRREPTLVRNDQKFHTVEEEARINRERKVEVIKPLVAETDTSSRPTFVVGNSTLDSSLELEMQEPEIQIPSEPRPNEECLQILGNAEKGAKFLS----------------------------------------DAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSKKLPE-PSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRILADGMT--PVVRFPRACDSAEVKAWLETPEGFAVIKEAFDSTSRFARLQKLQMSVAGRNLYIRFQSRSGDAMGMNMISKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAVNWIEGRGKSVVCEAVIPAKVVREVLKTTTEAMVEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTSLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMIHNRSKINLQDL 876
BLAST of EMLSAG00000004979 vs. Select Arthropod Genomes
Match: gb|KYB27676.1| (3-hydroxy-3-methylglutaryl-coenzyme A reductase-like Protein [Tribolium castaneum]) HSP 1 Score: 642.884 bits (1657), Expect = 0.000e+0 Identity = 378/881 (42.91%), Postives = 532/881 (60.39%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTFVPLDGGSPEWSP---------------------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY----AFLLSMTAFLL------GGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXL--ITSPQGQAKWNVKRILETLPTQEPPSRTPLRVLAFPVLVLLHLTCLQPPSLQLHIQNTPHIIISLSLVLLSYYFYSNKDEDATSLH------LRKSYEEAFTRK-----------LQDQDSSVSRLKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPP--RSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAV 838
G+ PWEV+ +LT ++T +D P P +V+ + R L++L Y Q + +LGS +L +AGL+ +F+ + T L DA F LLL D+ K L Q ALSA+++ + ++R M L PT+ DT+++ L+ + L +L ++L+ VF YP LS+ L L T+ G + + R L+ + P ++++ L+L+H + P + ++N +++ + L N+ ED T+LH + S + ++++ +L+ + +++S D G K L K++ + +++ +SA +D+E QT D R E+ E L +G+ S RS+E CL I N L+D+EV+ LV+ +HI ++ +EK ++D RGV +RRK+++R E + +A LP++++DY VMGACCE+V+GYMPVPVG GPL LD + ++PMATTEGCLVASTNRGC AL CG VTS++ DGM+RGPVVRFP+++ A +A W++ N++ +K FDS+SRFARL+KL +++AGR +++RF AKTGDAMGMNM+SK TE +L + FPEM+I+S+SGN CTDKKPAAVNWIEGRGKSVVCEAI+P+ IV+ +LKTST ALVD+N++KN GSA+AGSIGGFNAH+ANIVTAI+IATGQD AQNIGSSNCMTLMEPWG G+DLY++CTMPSIE+GT+GGGT+L Q SCLEML VKG HP PGEN+ QLARI+CG VLAGELSLM+AL AG LV SHLRHNRST +
Sbjct: 10 GEFCATHPWEVIVATLTLAACMLT---VDQQHPAPPPKPTLRYCAECLQEAEYNAADLIVMTLIRCLAVLYCYYQFCNLEKLGSKYILGIAGLFTVFSSFVFTSTVLNLLWIDVSDLKDALFFFLLLIDLSKAAMLAQSALSASNQEEVKSNIARGMAVLGPTITLDTIVETLVIGVGTLSGVHRLEMLSYFACLSVLVNYIVFMTFYPACLSLILELSRTTNIYGNKQSLIARALKEEDHKSNPVVQRVKLIMSAGLMLVHARS-RWPFKEDDVENIRPLVVEQHMTL-------NRTED-TTLHEYIMKWVTVSADHIVILILLLALVVKFVFFENKEELAEQLRAHI--STESVDPG---KKDNRFKMPLIKTQSFFLTNNTKEDSA--------CEDKEVQT----------DIGRLESEFEK-----LPAGNDVSVKTCRSLEECLKIY--NDSNLGGAALSDDEVILLVKNKHIPAYQIEKAVDDPERGVGIRRKILAR-EGNFSEALTDLPFRNYDYAKVMGACCENVIGYMPVPVGYAGPLNLDGRHVYVPMATTEGCLVASTNRGCRALLDCG-VTSRVVSDGMTRGPVVRFPSITKASEAMSWMKCSQNFEAMKQQFDSSSRFARLSKLLIKIAGRHLFVRFEAKTGDAMGMNMVSKGTEMSLKYVQKQFPEMEILSLSGNFCTDKKPAAVNWIEGRGKSVVCEAIIPSEIVKKVLKTSTPALVDVNNSKNMIGSAVAGSIGGFNAHAANIVTAIYIATGQDPAQNIGSSNCMTLMEPWGETGEDLYVSCTMPSIEIGTVGGGTVLPAQSSCLEMLRVKGSHPDCPGENASQLARIVCGTVLAGELSLMAALTAGHLVRSHLRHNRSTTTI 846
BLAST of EMLSAG00000004979 vs. Select Arthropod Genomes
Match: XP_623118.1 (PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase isoform X1 [Apis mellifera]) HSP 1 Score: 641.728 bits (1654), Expect = 0.000e+0 Identity = 372/844 (44.08%), Postives = 500/844 (59.24%), Query Frame = 0
Query: 55 VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLYAFLLSMTAFLLGG----------PDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLITSPQGQAKWNVKRILETLPTQEP-----PSRTPLRVLAFPVLVLLHLTCL-----QPPSLQLHIQNT-PHIIISLSLVLLSYYFYSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSRL------------KDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSS------------------SESAWSEVYMPDLKDQEAQTTE-ECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAV 838
+V+ + R L++L Y Q + + +LGS +L +AGL+ S+ DA F LL+ D+ K L Q ALS+ ++ + ++R M L PT+ DTL++ LL ++ L +L S +++ VF YP LS+ L L + +I P E P ++++ L ++H +++ + +T H+I++ SY N+ ED++ + K Y + D + L K+D+ + Q E K N KK +I V D + S + + +P + +E Q E +C V +S+D++ L S PRS+E CL I K N LTDEEV+ LV+ HI ++ LEK + D RGV +RR +I L LPYK +DY V+GACCE+V+GY+PVP+G+ GPL LD +LY++PMATTEGCLVASTNRG AL KCG VTS++ DGM+RGPVVRFPN+ A +A W++DP N++E+K+SF+ TSRFARL K+ +R+AGR +++RFVA TGDAMGMNMLSK TE +LN + FP+M+I+S+SGN CTDKKPAAVNW+ GRGKSVVCEA+VPA IV +LKTS ALVD+N +KN GSA+AGSIGGFNAH+ANIVTAIFIATGQD AQN+GSSNCMTLMEPWG DG DLY++CTMPSIE+GT+GGGTIL QG+CL +LGVKG H PGEN+ +LARI+C VLAGELSLM+AL AG LV SHLRHNRS+ V
Sbjct: 65 IVMTIIRCLAILFTYHQFRNLQKLGSKYILGIAGLFTVFSSVVFTSSVVNFGRSDISDLKDALFFFLLIIDLSKAAVLAQLALSSRNKEEVRANIARGMSLLGPTITLDTLVETLLISIGSLSGVRRLEILCSFACLGVVVNYIVFMTFYPACLSLILELSRETNTMKPLSADKIFMMHPLDEEDQKPNPVVERVKLIMIAGLFVVHANSRFKSEESEDTVEGKVSSTNSHVIVN------SY----NETEDSSEV---KGYLMNWLSVSADNIVILILLLALAIKFIFFEDKEDIAKQLQFKVEDDTEEKIENEYMKEKKFEIEYVKDKENENEDMNFSFLTTKMPFKLSFAKMQTISIPWIDGKEEQIDEKQCTVNTSNDKN-------------LFS----QIPRSVEECLKIYKSELGAN---GLTDEEVIQLVKNNHIAAYQLEKAVGDMERGVEIRRFIIGEAGNFLD-YLSNLPYKDYDYSKVLGACCENVMGYVPVPLGIAGPLLLDGELYYVPMATTEGCLVASTNRGSRALLKCG-VTSRVVADGMTRGPVVRFPNIVRASEAMAWMQDPDNFKEMKNSFNLTSRFARLTKINIRIAGRHLFIRFVATTGDAMGMNMLSKGTEKSLNTVKEHFPDMEILSLSGNFCTDKKPAAVNWVCGRGKSVVCEAVVPADIVTNVLKTSVHALVDVNISKNMIGSAIAGSIGGFNAHAANIVTAIFIATGQDPAQNVGSSNCMTLMEPWGTDGSDLYVSCTMPSIEIGTVGGGTILPAQGACLSILGVKGAHSDEPGENASRLARIVCATVLAGELSLMAALTAGHLVKSHLRHNRSSTTV 873
BLAST of EMLSAG00000004979 vs. Select Arthropod Genomes
Match: XP_016773303.1 (PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase isoform X1 [Apis mellifera]) HSP 1 Score: 641.728 bits (1654), Expect = 0.000e+0 Identity = 372/844 (44.08%), Postives = 500/844 (59.24%), Query Frame = 0
Query: 55 VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLYAFLLSMTAFLLGG----------PDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLITSPQGQAKWNVKRILETLPTQEP-----PSRTPLRVLAFPVLVLLHLTCL-----QPPSLQLHIQNT-PHIIISLSLVLLSYYFYSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSRL------------KDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSS------------------SESAWSEVYMPDLKDQEAQTTE-ECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAV 838
+V+ + R L++L Y Q + + +LGS +L +AGL+ S+ DA F LL+ D+ K L Q ALS+ ++ + ++R M L PT+ DTL++ LL ++ L +L S +++ VF YP LS+ L L + +I P E P ++++ L ++H +++ + +T H+I++ SY N+ ED++ + K Y + D + L K+D+ + Q E K N KK +I V D + S + + +P + +E Q E +C V +S+D++ L S PRS+E CL I K N LTDEEV+ LV+ HI ++ LEK + D RGV +RR +I L LPYK +DY V+GACCE+V+GY+PVP+G+ GPL LD +LY++PMATTEGCLVASTNRG AL KCG VTS++ DGM+RGPVVRFPN+ A +A W++DP N++E+K+SF+ TSRFARL K+ +R+AGR +++RFVA TGDAMGMNMLSK TE +LN + FP+M+I+S+SGN CTDKKPAAVNW+ GRGKSVVCEA+VPA IV +LKTS ALVD+N +KN GSA+AGSIGGFNAH+ANIVTAIFIATGQD AQN+GSSNCMTLMEPWG DG DLY++CTMPSIE+GT+GGGTIL QG+CL +LGVKG H PGEN+ +LARI+C VLAGELSLM+AL AG LV SHLRHNRS+ V
Sbjct: 65 IVMTIIRCLAILFTYHQFRNLQKLGSKYILGIAGLFTVFSSVVFTSSVVNFGRSDISDLKDALFFFLLIIDLSKAAVLAQLALSSRNKEEVRANIARGMSLLGPTITLDTLVETLLISIGSLSGVRRLEILCSFACLGVVVNYIVFMTFYPACLSLILELSRETNTMKPLSADKIFMMHPLDEEDQKPNPVVERVKLIMIAGLFVVHANSRFKSEESEDTVEGKVSSTNSHVIVN------SY----NETEDSSEV---KGYLMNWLSVSADNIVILILLLALAIKFIFFEDKEDIAKQLQFKVEDDTEEKIENEYMKEKKFEIEYVKDKENENEDMNFSFLTTKMPFKLSFAKMQTISIPWIDGKEEQIDEKQCTVNTSNDKN-------------LFS----QIPRSVEECLKIYKSELGAN---GLTDEEVIQLVKNNHIAAYQLEKAVGDMERGVEIRRFIIGEAGNFLD-YLSNLPYKDYDYSKVLGACCENVMGYVPVPLGIAGPLLLDGELYYVPMATTEGCLVASTNRGSRALLKCG-VTSRVVADGMTRGPVVRFPNIVRASEAMAWMQDPDNFKEMKNSFNLTSRFARLTKINIRIAGRHLFIRFVATTGDAMGMNMLSKGTEKSLNTVKEHFPDMEILSLSGNFCTDKKPAAVNWVCGRGKSVVCEAVVPADIVTNVLKTSVHALVDVNISKNMIGSAIAGSIGGFNAHAANIVTAIFIATGQDPAQNVGSSNCMTLMEPWGTDGSDLYVSCTMPSIEIGTVGGGTILPAQGACLSILGVKGAHSDEPGENASRLARIVCATVLAGELSLMAALTAGHLVKSHLRHNRSSTTV 873
BLAST of EMLSAG00000004979 vs. Select Arthropod Genomes
Match: XP_006571385.1 (PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase isoform X1 [Apis mellifera]) HSP 1 Score: 641.728 bits (1654), Expect = 0.000e+0 Identity = 372/844 (44.08%), Postives = 500/844 (59.24%), Query Frame = 0
Query: 55 VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLYAFLLSMTAFLLGG----------PDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLITSPQGQAKWNVKRILETLPTQEP-----PSRTPLRVLAFPVLVLLHLTCL-----QPPSLQLHIQNT-PHIIISLSLVLLSYYFYSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSRL------------KDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSS------------------SESAWSEVYMPDLKDQEAQTTE-ECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAV 838
+V+ + R L++L Y Q + + +LGS +L +AGL+ S+ DA F LL+ D+ K L Q ALS+ ++ + ++R M L PT+ DTL++ LL ++ L +L S +++ VF YP LS+ L L + +I P E P ++++ L ++H +++ + +T H+I++ SY N+ ED++ + K Y + D + L K+D+ + Q E K N KK +I V D + S + + +P + +E Q E +C V +S+D++ L S PRS+E CL I K N LTDEEV+ LV+ HI ++ LEK + D RGV +RR +I L LPYK +DY V+GACCE+V+GY+PVP+G+ GPL LD +LY++PMATTEGCLVASTNRG AL KCG VTS++ DGM+RGPVVRFPN+ A +A W++DP N++E+K+SF+ TSRFARL K+ +R+AGR +++RFVA TGDAMGMNMLSK TE +LN + FP+M+I+S+SGN CTDKKPAAVNW+ GRGKSVVCEA+VPA IV +LKTS ALVD+N +KN GSA+AGSIGGFNAH+ANIVTAIFIATGQD AQN+GSSNCMTLMEPWG DG DLY++CTMPSIE+GT+GGGTIL QG+CL +LGVKG H PGEN+ +LARI+C VLAGELSLM+AL AG LV SHLRHNRS+ V
Sbjct: 65 IVMTIIRCLAILFTYHQFRNLQKLGSKYILGIAGLFTVFSSVVFTSSVVNFGRSDISDLKDALFFFLLIIDLSKAAVLAQLALSSRNKEEVRANIARGMSLLGPTITLDTLVETLLISIGSLSGVRRLEILCSFACLGVVVNYIVFMTFYPACLSLILELSRETNTMKPLSADKIFMMHPLDEEDQKPNPVVERVKLIMIAGLFVVHANSRFKSEESEDTVEGKVSSTNSHVIVN------SY----NETEDSSEV---KGYLMNWLSVSADNIVILILLLALAIKFIFFEDKEDIAKQLQFKVEDDTEEKIENEYMKEKKFEIEYVKDKENENEDMNFSFLTTKMPFKLSFAKMQTISIPWIDGKEEQIDEKQCTVNTSNDKN-------------LFS----QIPRSVEECLKIYKSELGAN---GLTDEEVIQLVKNNHIAAYQLEKAVGDMERGVEIRRFIIGEAGNFLD-YLSNLPYKDYDYSKVLGACCENVMGYVPVPLGIAGPLLLDGELYYVPMATTEGCLVASTNRGSRALLKCG-VTSRVVADGMTRGPVVRFPNIVRASEAMAWMQDPDNFKEMKNSFNLTSRFARLTKINIRIAGRHLFIRFVATTGDAMGMNMLSKGTEKSLNTVKEHFPDMEILSLSGNFCTDKKPAAVNWVCGRGKSVVCEAVVPADIVTNVLKTSVHALVDVNISKNMIGSAIAGSIGGFNAHAANIVTAIFIATGQDPAQNVGSSNCMTLMEPWGTDGSDLYVSCTMPSIEIGTVGGGTILPAQGACLSILGVKGAHSDEPGENASRLARIVCATVLAGELSLMAALTAGHLVKSHLRHNRSSTTV 873
BLAST of EMLSAG00000004979 vs. Select Arthropod Genomes
Match: EEB15787.1 (3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative [Pediculus humanus corporis]) HSP 1 Score: 625.55 bits (1612), Expect = 0.000e+0 Identity = 365/839 (43.50%), Postives = 517/839 (61.62%), Query Frame = 0
Query: 55 VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY----AFLLSMTA--FLLGG----PDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLI-TSPQGQAKWNVKRILETLPT--QEPPSRTPLRV-------------------------LAFPVLVLLHLTCLQP---PSLQLHIQ-----NTPHIIISLSL--VLLSYYFYSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSRLKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLKDQEAQTTEECL--VVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRST 835
+++ + R ++L Y +H+LGS +L ++GL+ +F+ S T F+ G DA F LLL D+ K T L Q+ALS++ + +++ M L P + DTL++ L+ + L +L ++++ VF YP LS+ L L +G+ W K ++ T QE P+ RV + P+ V+ H+ L P L +I N I+I + L V + + + K++ H K + D+ +V+ D +S T E + +D SK+L +SES SEV+ L+D++ + ++ +V ++ +TL+E + + + R ++ C+ + KE L+D+EV+ LV + I ++ LEK +ND RGV +RRK++S + + ++A E LPY ++DY VMGACCE+V+GY+PVPVG+ GPL LD KL ++PMATTEGCLVASTNRG AL KCG V S++ DGM+RGPV+RFPN++ A +A W+++P N++ +K SFDS+SRFARL+K+ +++A R +++RF+A+TGDAMGMNMLSK TE ALN + F +M+I+S+SGN C DKKPAAVNWIEGRGKSVV EAIVPA +V +LKTS AL+D+N KN GSA+AGSIGGFNAH+ANIVTAIFIATGQD AQN+GSSNC+TLMEPWG DG DLYI+C+MPSIE+GT+GGGT+L PQ +CL+MLGVKG + +PGEN+ +LARI+CG VLAGELSLMSALAAG LV SHL+HNRS+
Sbjct: 68 IMMTIIRCTAILYSYYHFCNLHKLGSKYILGISGLFTVFSSFVFSSTVINFMNGDISDLKDALFFFLLLIDLSKATLLAQFALSSSSPEEVKHNIAKGMAKLGPIITLDTLVETLVIGVGTLSGVRRLEVLCGFACMSVVVNYIVFMTFYPACLSLILELSRIGEKGRIMWQNKFMVFKALTEEQEKPNPVVQRVKIIMSAGLMIVHARSRWTFQPEEEEMVSPLAVVDHMLPLNATGEPLLHYNIMRWITVNADQIVILVLLFAVTIKFVLFEEKEQ-----HFFKP------NVITDEVKNVNN-----DSSSPETQE---------TETD---SKLLF-----NSESI-SEVFSDSLEDKQVKIDKQIQTEMVKPGFDNNSKTLAE----TKVTELPVKNSDRDLDECIKLFKELGAE----ALSDDEVMRLVRNKQIAAYQLEKAVNDPERGVGIRRKIVSS-DGNFREALENLPYTNYDYSLVMGACCENVIGYVPVPVGVAGPLLLDGKLVYVPMATTEGCLVASTNRGSRALLKCG-VISRVVSDGMTRGPVIRFPNMARASEAMTWMQNPENFEILKASFDSSSRFARLSKIHIKIASRHLFVRFIAQTGDAMGMNMLSKGTEIALNTVKEHFSDMEILSLSGNFCADKKPAAVNWIEGRGKSVVAEAIVPADVVTNVLKTSVQALIDVNITKNLIGSAVAGSIGGFNAHAANIVTAIFIATGQDPAQNVGSSNCITLMEPWGDDGNDLYISCSMPSIEIGTVGGGTVLPPQSACLDMLGVKGSNEKNPGENACKLARIVCGTVLAGELSLMSALAAGHLVRSHLKHNRSS 862
BLAST of EMLSAG00000004979 vs. Select Arthropod Genomes
Match: XP_006571386.1 (PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase isoform X2 [Apis mellifera]) HSP 1 Score: 608.601 bits (1568), Expect = 0.000e+0 Identity = 336/747 (44.98%), Postives = 456/747 (61.04%), Query Frame = 0
Query: 143 MQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLITSPQGQAKWNVKRILETLPTQEP-----PSRTPLRVLAFPVLVLLHLTCL-----QPPSLQLHIQNT-PHIIIS------------------LSL-------------VLLSYYFYSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSRLKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLKDQEAQTTE-ECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAV 838
M L PT+ DTL++ LL ++ L +L S +++ VF YP LS+ L L + +I P E P ++++ L ++H +++ + +T H+I++ LS+ + + + F+ +K++ A L + E+ K++++ + + + + ++ +E D+ S + S + + +P + +E Q E +C V +S+D++ L S PRS+E CL I K N LTDEEV+ LV+ HI ++ LEK + D RGV +RR +I L LPYK +DY V+GACCE+V+GY+PVP+G+ GPL LD +LY++PMATTEGCLVASTNRG AL KCG VTS++ DGM+RGPVVRFPN+ A +A W++DP N++E+K+SF+ TSRFARL K+ +R+AGR +++RFVA TGDAMGMNMLSK TE +LN + FP+M+I+S+SGN CTDKKPAAVNW+ GRGKSVVCEA+VPA IV +LKTS ALVD+N +KN GSA+AGSIGGFNAH+ANIVTAIFIATGQD AQN+GSSNCMTLMEPWG DG DLY++CTMPSIE+GT+GGGTIL QG+CL +LGVKG H PGEN+ +LARI+C VLAGELSLM+AL AG LV SHLRHNRS+ V
Sbjct: 1 MSLLGPTITLDTLVETLLISIGSLSGVRRLEILCSFACLGVVVNYIVFMTFYPACLSLILELSRETNTMKPLSADKIFMMHPLDEEDQKPNPVVERVKLIMIAGLFVVHANSRFKSEESEDTVEGKVSSTNSHVIVNSYNETEDSSEVKGYLMNWLSVSADNIVILILLLALAIKFIFFEDKEDIAKQLQFK--VEDDTEEKIENEYMKEKKFEIEYVKDKENENE------------DMNFSFLTTKMPFKLSFAKMQTISIPWIDGKEEQIDEKQCTVNTSNDKN-------------LFS----QIPRSVEECLKIYKSELGAN---GLTDEEVIQLVKNNHIAAYQLEKAVGDMERGVEIRRFIIGEAGNFLD-YLSNLPYKDYDYSKVLGACCENVMGYVPVPLGIAGPLLLDGELYYVPMATTEGCLVASTNRGSRALLKCG-VTSRVVADGMTRGPVVRFPNIVRASEAMAWMQDPDNFKEMKNSFNLTSRFARLTKINIRIAGRHLFIRFVATTGDAMGMNMLSKGTEKSLNTVKEHFPDMEILSLSGNFCTDKKPAAVNWVCGRGKSVVCEAVVPADIVTNVLKTSVHALVDVNISKNMIGSAIAGSIGGFNAHAANIVTAIFIATGQDPAQNVGSSNCMTLMEPWGTDGSDLYVSCTMPSIEIGTVGGGTILPAQGACLSILGVKGAHSDEPGENASRLARIVCATVLAGELSLMAALTAGHLVKSHLRHNRSSTTV 711
BLAST of EMLSAG00000004979 vs. Select Arthropod Genomes
Match: gb|EFA06636.1| (3-hydroxy-3-methylglutaryl-coenzyme A reductase-like Protein [Tribolium castaneum]) HSP 1 Score: 597.816 bits (1540), Expect = 0.000e+0 Identity = 354/877 (40.36%), Postives = 495/877 (56.44%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTF--------VPLDGGSPEW----SPVVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY----AFLLSMTAF------LLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXL--ITSPQGQAKWNVKRILETLPTQEPPSRTPLRVLAFPVLVLLHLTC---LQPPSLQLH-IQNTPH------------------------IIISLSLVLLSYYFYSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSRLKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRS 834
G PWEV+ +T L+T P G E +V+ V R L++L Q + + +LGS +L +AGL+ +F+ + T L+ DA F LLL D+ K L Q+AL+A+ + + +++R M L PT+ DT+++ L+ + L +L ++L+ +F YP LS+ L L I++ G+ + V ++L + P+ ++++ L +H+ ++ S I NT H I+I + +++ + F+ N D HL+++ ++ L+ Q + ++ Q+ DE I L + + EECL + SD + E LL H P ++E+ A +N+ RGV +RR+LI + + AF LPYKH+DY VMGACCE+V+GY+PVP+G+ GPL LD K Y+IPM+TTEGCL+AS NRGC A+ C G+ S+I DGM+RGPVVRF +++ A + WLE P N+ ++K++FDSTSRFARL+++ R+AGR ++LRFVA+TGDAMGMNMLSK TE AL + FPEM+I+S+SGN C DKKPAAVNW+EGRGKSVVCEAIV +V ++LK+ST LVDLN++KN GSAMAGSIGGFNAH+ANIVTAIFIATGQD AQNI SSNC+T+MEPWG +G+DLY++CTMPSIE+GTIGGGTIL Q +CL+MLGV+GP+ SPG NS+QLARI+C VLAGELSLM+ALA G LV SHL++NRS
Sbjct: 9 GSFCATHPWEVIVAVVTLTTCLLTVDQKKEPPAQPCPGCFEEQFKAVDVIVMTVIRCLAILYSSHQFRNLQKLGSKYILGLAGLFIVFSSFVFTSTVLNFLQIDLVDLKDALFFFLLLIDLSKAATLAQFALTASSQEEISSKIARGMSVLGPTITLDTVVETLVIGVGTLSGVHRLEMLSYFACLSVLVNYVIFMTFYPACLSLMLELARISNFYGEKQPIVSKMLLEENEKANPAVQRVKLIMSIGLTAVHVHSRWFVKDESTDSEIITNTDHQNCAEDSVYGYLMKQFALSADHIVILILVVTLIIKFIFFENDD------HLKQAIDDEPPHVLKRQKCITKAESINEEKEVQTNDEEI-----------------------------------ESLDETNTRNLEECLQIYRSDGASKLSDKE----VILLIDTKHLPAYNLEK--------AVKNQE------------------------------RGVKIRRQLIQSLAK-CESAFLNLPYKHYDYSKVMGACCENVIGYIPVPLGVAGPLVLDGKQYYIPMSTTEGCLIASANRGCRAVEHC-GIKSRIVSDGMTRGPVVRFNSITKASEVTLWLEKPENFLKVKENFDSTSRFARLSRITSRVAGRYLFLRFVAETGDAMGMNMLSKGTEKALFFVQRFFPEMEILSLSGNYCADKKPAAVNWVEGRGKSVVCEAIVSGDVVSSVLKSSTQVLVDLNTSKNMIGSAMAGSIGGFNAHAANIVTAIFIATGQDPAQNIASSNCITIMEPWGDNGQDLYVSCTMPSIEIGTIGGGTILPAQSACLDMLGVRGPNEESPGANSKQLARIVCATVLAGELSLMAALATGQLVKSHLKYNRS 800
BLAST of EMLSAG00000004979 vs. Select Arthropod Genomes
Match: gb|KFM69136.1| (3-hydroxy-3-methylglutaryl-coenzyme A reductase, partial [Stegodyphus mimosarum]) HSP 1 Score: 582.793 bits (1501), Expect = 0.000e+0 Identity = 370/909 (40.70%), Postives = 511/909 (56.22%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLL-----SLVTFVPLDGGSPEWSP-------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY---------AFLLSMTAFLLGG----PDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLITS-PQGQAKWNVK---RILETLPTQEP-PSRTPLRVLAFPVLVLLHLTCLQP-----PSLQ------------------LHIQ-----NTPHIIISL--SLVLLSYYFYSNKD------EDATSLHLRKSYEEAFTRKLQD------QDSSVSRLKDDLDRASQSTDEGIGLTKSANSASDLKKSKILV--VGDDSSSESAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGK-DLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAVGKLAE 843
G+ PWEV+ LT +L + G E S V++ V R + +L + Q R+++LGS L+ + GL+ F +S FL G A LL D+ K L Q+ALS++ + + + +++ M L PT+ DT+++ L+ + L L + ++ FVF +P LS+ L L +G+ W++ RIL+ Q+P P ++V+ LVL+H P +LQ +++Q + P I+I+L ++ + YF S +D A S R Y TR Q + ++ ++ L + T + G + N +S +LV V S+S + E + ++ D+ QT + +R+ D PRSIE C IL+ LT++E++ L E+R I+SH LE ++N+ RGV +RRKL+ + + + E LPY +DY VMG+CCE+V+GY+P+PVG+ GPL LD ++ +IPMATTEGCLVASTNRGC AL+ GGV S + DGM+RGPVV+ P+ + A K W+E N++ +K SFDSTSRFARL K+ V++AG YLRF A TGDAMGMNMLSK + ALNKL IFP ++IIS+SGN CTDKKPAA+NWI+GRGK VVC A +PA +V+ +LKT A L+ LN KN GSAMAGSIGGFNA +ANIVTAIF+ATGQD AQN+ SSNC+T++E D K DL I+CTMPSIEVGT+GGGT L Q SCLEMLGVKGP +PG N+ +LARIIC VLAGELSL+SALA G LV SH+ HNRS+L V L +
Sbjct: 10 GRLCASHPWEVIIAFLTLILWKLSTGTAYISNVKGCGYECSEENKSVEIVLLTVARCVGILYLVQQFLRLNKLGSTYLVAIGGLFTIFCLVPCIVFSISTVNFLKGDFTELNKALPFYFLLMDLTKAGLLAQFALSSSTQEEVEENIAQGMSILGPTITLDTIVEALVIGVGTLSGVKRLEELCRFACISAVINYFVFMIFFPACLSLILELSRDRDEGRPVWHLSTLTRILQQEEEQKPNPVLQRVKVIMSAGLVLVHAHSRWPLLVASKALQQASKASVSDSMGPYSNWDIYMQRWFGGSEPIIMIALLTTITFAANYFPSREDLTEHLASAAASSLSRSPYGFQITRTTQGIQTDSHEGHHSAKPQNSLCSRAVQTADCKGFPCNQNLVPSFVQSSMLVPCVTTQSASFTVGEEPNIVNITDEFVQT--------GATNNREVVPRTD-----------FKNPRSIEECKKILQSEVG---GIGLTEDEIILLAEKRIIQSHKLETIVNNPKRGVSIRRKLLGKLAKR-GEILESLPYADYDYKLVMGSCCENVIGYVPIPVGVAGPLLLDGEMLYIPMATTEGCLVASTNRGCRALALSGGVNSNLLADGMTRGPVVKLPSEAEAGNIKRWIEKKENFEVLKASFDSTSRFARLQKIDVQIAGCCAYLRFNAVTGDAMGMNMLSKGADKALNKLCEIFPSVEIISLSGNYCTDKKPAAINWIQGRGKYVVCGATIPAEVVKEVLKTDVATLIKLNIHKNFIGSAMAGSIGGFNAQAANIVTAIFLATGQDPAQNVTSSNCLTMLE----DLKGDLRISCTMPSIEVGTVGGGTFLPAQSSCLEMLGVKGPCEENPGNNAAKLARIICATVLAGELSLLSALAEGNLVRSHMTHNRSSLTVHSLLQ 891
BLAST of EMLSAG00000004979 vs. Select Arthropod Genomes
Match: EFX81008.1 (protein HMG coenzyme A reductase-like protein [Daphnia pulex]) HSP 1 Score: 576.244 bits (1484), Expect = 0.000e+0 Identity = 351/881 (39.84%), Postives = 502/881 (56.98%), Query Frame = 0
Query: 7 LKFLEDVSDCLGQATVKQPWEVLFVSLTSLLSLVTFVPLDG--------GSPEWSPVVVFV-FRFLSLLRMYVQLKRIHRLGSAVLLHVAGLYAFLLS----------MTAFLLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRL--SRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLITSPQGQA---KWN--VKRILETLPTQEP-PSRTPLRVLAFPVLVLLHLTCLQPPSLQLHIQNTPHIIISLSLVLLSYYFYSNKD----EDATSLHLRK---SYEEAFTRKLQDQDSSVSRLKDDLDRASQS---------TDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSP-PRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRRE-QHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRS 834
+ FL ++ G + PW+V+F+ LTS +++++ + GSP+ +V+ R +++L Y +L+ +HR S +L +AGL+ S M + L DA F LLL D+ K L ++LS + ++ L S+ M L P + DTL++ L+ + L +L + ++ VF YP L++ L + + Q+ +W VK + + + ++P P ++++ L+++H H +V L F+ +D L K ++ A + +DS + L D RA Q T + + + V+ D+ S D++D+E QT E C +ED +TL + P R++E A + ++D+EV+ L+ R I LEKVL D RGV +RR+++S L+ + +LPYK++DY V G CCE+V+GY+P+PVG GPL +D + Y IPMATTEGCLVASTNRGCSAL+ GGV +Q+ DGMSRGPV R P++ A WL++P N +K SF++TSRF RL K++ ++AGR +++RFVAKTGDAMGMNM+SK TE A+ + F ++ ++S+SGN CTDKKPAAVNW++GRGKSVV EAI+PA+IV LKT+ A+LVDLN KN GS++AGSIGGFNAH+ANIV+AIFIATGQD AQ + SSNCMTLMEPWGP+ +DLYI+CTMPS+EVGTIGGGT L QG+CL+MLG++G + PG N+ +LARIIC AVLAGELSLMS+LA G LV SH+ HNRS
Sbjct: 1 MGFLAEIFKSYGLFCAQHPWQVIFLVLTSTVAIISSQGMHTLNRARDSLGSPQPLDIVLMTTVRAVAVLYSYHRLRSLHRSHSRFVLSLAGLFTVFSSFVFTCSVVNVMQSDLSDLKDALFFFLLLIDVVKACTLAYWSLSCSVKNAAEVALCISQGMAVLGPAITLDTLVETLVIGVGTLSGVRRLEVLCGYGCMSAVVNYVVFMTFYPACLALVLEVNSCKVDQSTAFQWQHRVKLLKQMMAMEQPNPLVQRVKLIMAAGLMVVHA--------HSHFLTIFLCCFHCFVVCLFVCFFRCSQWVFLQDGKVLSPEKPGATFGSASIVDVAAEDSVLRWLSDQ--RADQLVLLILIAALTIKFTFFDDRNQTPHRRNRCVSFVISDNEESSF--------DVEDKEVQT-EPC---DEMEEDEQDTL-------------YVKPVTRTLEE-----SHEALKISGSAVSDQEVLNLINARKIELRQLEKVLGDAERGVRIRRRVLSTMGGTRLEDSVVRLPYKNYDYSKVFGVCCENVIGYVPLPVGFAGPLIVDGESYFIPMATTEGCLVASTNRGCSALAPNGGVRTQLIADGMSRGPVFRLPDIRRAGDVMAWLQEPSNIDLLKKSFNATSRFGRLQKIRCQIAGRHVFIRFVAKTGDAMGMNMVSKGTEAAIKVIQSHFADLAVVSLSGNFCTDKKPAAVNWLDGRGKSVVSEAIIPAAIVRDKLKTNVASLVDLNITKNLIGSSIAGSIGGFNAHAANIVSAIFIATGQDPAQVVSSSNCMTLMEPWGPEMQDLYISCTMPSLEVGTIGGGTWLPAQGACLDMLGLRGSNAEEPGANACRLARIICAAVLAGELSLMSSLATGTLVQSHMTHNRS 841
BLAST of EMLSAG00000004979 vs. Select Arthropod Genomes
Match: AAF56175.1 (HMG coenzyme A reductase [Drosophila melanogaster]) HSP 1 Score: 552.747 bits (1423), Expect = 0.000e+0 Identity = 339/861 (39.37%), Postives = 489/861 (56.79%), Query Frame = 0
Query: 46 DGGSPEWSP---VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLYAFLLSM---TAFL--LGG-----PDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXL------ITSPQGQAKWNVKRILETLPTQEP---PSRTPLRVLAFPVLVLLHLTC--------------LQPPSLQLHIQNT-------------------PHIIISLSLVLLSYYFYSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSRLKDDLDRASQST---DEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEE--RHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAV 838
DG E++ +++ + R ++L Y Q +HRLGS +L +AGL+ S TA + LG DA F +LL+ D+ +L Q ALS ++++ + ++R ++ L P + DT++++LL + L +L V ++L+ VF YP LS+ L ++ + +AK ++ +L++L +E P ++++ L+ +H+ P+L L++ N HI+IS+ L+ L F + D LR+S A K ASQ+T +E + K +++ ++ +L +D SS +A ++ + L+ H L G PPR ++ CL IL + + P L+DEE+V++V H H +E VL+D RGV +RR++I R + + LPY+HFDY V+ ACCE+V+GY+P+PVG GPL LD + Y++PMATTEG LVASTNRGC ALS GV S + D GM+R P VRFP+V+ A +AK W+E+ NY+ +K FDSTSRF RL + + G +Y+RFVA TGDAMGMNM+SK E AL ++ FP+MQIIS+SGN C DKKPAA+NWI+GRGK VV E + A+ + ++LKT LV+ N KN GSAMAGSIGG NAH+AN+VTA+F+ATGQD AQN+ SSNC T ME W + +DLY+TCTMPS+EVGT+GGGT L Q +CLEMLGV+G H T PG+N+++LA+I+C V+AGELSLM+AL LV SH+RHNRS++AV
Sbjct: 96 DGLEAEYNAADVILMTIVRCTAVLYCYYQFCSLHRLGSKYVLGIAGLFTVFSSFIFTTAIIKFLGSDISELKDALFFLLLVIDLSNSGRLAQLALSGSNQAEVTQNIARGLELLGPAISLDTIVEVLLVGVGTLSGVQRLEVLCMFAVLSVLVNYVVFMTFYPACLSLIFDLSRSGVDMSVVREKAKGSL--LLKSLTEEEQKANPVLQRVKLIMTTGLMAVHIYSRVAFSGSDYDAVDKTLTPTLSLNVSNNRTESGEIADIIIKWLTMSADHIVISIVLIALVVKFICFDNRDPLPDQLRQSGPVAIAAK-----------------ASQTTPIDEEHVEQEKDTENSAAVRT--LLFTIEDQSSANASTQTDLLPLR-------------------------------HRLVGPIK-PPRPVQECLDILNSTEEGSGPAALSDEEIVSIVHAGGTHCPLHKIESVLDDPERGVRIRRQIIGSRAKMPVGRLDVLPYEHFDYRKVLNACCENVLGYVPIPVGYAGPLLLDGETYYVPMATTEGALVASTNRGCKALS-VRGVRSVVEDVGMTRAPCVRFPSVARAAEAKSWIENDENYRVVKTEFDSTSRFGRLKDCHIAMDGPQLYIRFVAITGDAMGMNMVSKGAEMALRRIQLQFPDMQIISLSGNFCCDKKPAAINWIKGRGKRVVTECTISAATLRSVLKTDAKTLVECNKLKNMGGSAMAGSIGGNNAHAANMVTAVFLATGQDPAQNVTSSNCSTAMECWAENSEDLYMTCTMPSLEVGTVGGGTGLPGQSACLEMLGVRGAHATRPGDNAKKLAQIVCATVMAGELSLMAALVNSDLVKSHMRHNRSSIAV 902
BLAST of EMLSAG00000004979 vs. nr
Match: gi|936704634|ref|XP_014230286.1| (PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase [Trichogramma pretiosum] >gi|936704636|ref|XP_014230287.1| PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase [Trichogramma pretiosum] >gi|936704638|ref|XP_014230288.1| PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase [Trichogramma pretiosum] >gi|936704640|ref|XP_014230290.1| PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase [Trichogramma pretiosum]) HSP 1 Score: 650.973 bits (1678), Expect = 0.000e+0 Identity = 375/864 (43.40%), Postives = 515/864 (59.61%), Query Frame = 0
Query: 48 GSPEWSP---VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLYA------FLLSMTAF----LLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLITSPQGQAKWNVKRILETLPTQEPPSRTPLRVLAFPVLVLLH-----------------------------LTCLQ-----PPSLQLHIQN-----TPHIIISLSLVLLS--YYFYSNKDEDATSLHLRKSYEEAFTRKLQD--------QDSSVSRLKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMP---DLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAV 838
GS E +P +++ V R L++L Y Q + + LGS +L +AGL+ F LS+ F + DA F LL+ D+ K L Q AL++ + + ++R M L P++ DTL+++LL + L +L +++ VF YP LS+ L L S + + +L + P L+++ L ++H LT + PP + N +I+I + LV L+ + F+ ++ E A L L + + K D QDS+ S D L R +A S+ S + G ++ W EV +L D+E QT ++ + T++ G+ S SPPRS++ CL I + + LTD EV+ LV ++I+S+ LEK + D RGV +RR L++ E + LPY+++DY V+G+CCE+V+GY+PVP G+ GPL +D +L+H+PMATTEGCLVASTNRG AL CG VTS++ DGM+RGPVVRFPNV A +A W++ P N++++K SFD TSRFARL K+ VR+AGR +++RFVA+TGDAMGMNMLSK TE +L ++ +FP+M+I+S+SGN CTDKKPAAVNWIEGRGKSVVCEA+VP IV ++LKTST ALVD+N +KN GSA+AGSIGGFNAH+ANIVTAIFIATGQD AQN+GSSNCMTLMEPWGP G+DLY++CTMPSIE+GT+GGGT L QG+CL+MLGVKG + PG+N+ +LARI+C VLAGELSLM+AL AG LV SHLRHNRS+ V
Sbjct: 82 GSEELNPADVILMTVIRCLAILFSYHQFRNLQNLGSKYILGIAGLFTMFSSIIFTLSVLNFGRSDISDLKDALFFFLLVIDLNKAAILAQLALNSKRQDEVRANIARGMSLLGPSVTLDTLVEILLIGIGSLSGVKRLEILCGYACLGVVVNYVVFMTFYPACLSLVLELSRSSNDKIIMSHGSLLNEEDQKPNPVVERLKLIMIAGLFVVHAHSRWPFRTDDAEEAIDEQVASSVNPGILLTTNRNKTESPPDYRGFFMNWLSVSADNIVILILLVALAIKFIFFEDRGEIARQLRLEEEQRDEEESKQDDEEKKQEKEQDSNSSEEMDRLTRRFAGAMATTLTATTAGSSHRTGPSSKVFAGLVAAPGEDWIEVGAEADVELVDKEVQTEQQQQQQVA-------TITSSGTVSKSNDDAATSPPRSVDECLAIYRSELGAS---VLTDAEVIQLVRAKYIQSYQLEKAVGDMERGVGIRRTLLNEAEVCITA---DLPYRNYDYSKVLGSCCENVIGYVPVPCGIAGPLLVDGELFHVPMATTEGCLVASTNRGSRALMGCG-VTSRVVADGMTRGPVVRFPNVVRASEAMAWMQQPENFEKMKSSFDETSRFARLTKIHVRIAGRHLFVRFVARTGDAMGMNMLSKGTEKSLLQVQRLFPDMEILSLSGNFCTDKKPAAVNWIEGRGKSVVCEAVVPGDIVSSVLKTSTQALVDVNMSKNMIGSAVAGSIGGFNAHAANIVTAIFIATGQDPAQNVGSSNCMTLMEPWGPTGEDLYVSCTMPSIEIGTVGGGTGLPAQGACLQMLGVKGANMEHPGQNADKLARIVCATVLAGELSLMAALTAGHLVKSHLRHNRSSTTV 931
BLAST of EMLSAG00000004979 vs. nr
Match: gi|407027843|dbj|BAM45097.1| (3-hydroxy-3-methylglutaryl coenzyme A reductase [Nasutitermes takasagoensis]) HSP 1 Score: 647.892 bits (1670), Expect = 0.000e+0 Identity = 387/883 (43.83%), Postives = 522/883 (59.12%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTFVPLDGGSPE-------WSP-------------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLYA-------------FLLSMTAFLLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLITSPQGQAKWNVKRILETLPTQEPPSRTPLRVLAFPVLVLLHLTCLQPPSLQLHIQNTPHIIISLSLVLL---SYYFYSNKDEDATSLHLRKSYEEAFTRKLQD---QDSSVSRLKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSES------AWSEV-YMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLL---SGDHHSP-----PRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAV 838
G+ PWEV+ +LT L ++T G P W +V+ + R +++L Y Q +H+LGS +L +AGL+ FL S + L DA F LLL D+ K T L Q+ALS+ + + ++ + L PT+ DT+++ L+ + L +L ++++ VF YP LS+ L L S G++ W PT SR ++ LH P +Q +I+S L+L+ S + ++++ E+ ++L + D Q + L D K +K+ G + + S W EV P +D TE S D+DE +S+ SS LL S D +P RS+E CL I + A LTD EV+ L+ HI SH LEK + + RGV +RRK ++R + L A LPY+H+DY VMGACCE+V+GYMPVPVG+ GPL LD L H+P+ATTEGCLVASTNRG AL +CG V+S+I DGM+RGPVVRFPN+S A +A W+++ N++ I+DSF+STSRFARL+++ +R+AGR +++RFVAKTGDAMGMNMLSK TE AL + FP+M+++S+SGN CTDKK AAVNWIEGRGKSVVCEA+VPA +V +ILKT+ ALVD+N +KN GSA+AGSIGGFNAH+ANIVTAIFIATGQD AQN+GSSNCMTLMEPWG DG+DLY++CTMPSIE+GT+GGGT+L PQ +CLEMLGV+G + PGEN+ +LARI+CG VLAGELSLMSALAAG LV SHL+HNR+++ +
Sbjct: 10 GELCASHPWEVIVTTLTLALCMMTVDQRPVGLPPEPHVECGWKNNCVGPEDYNAADVIVMTLIRCVAVLYSYYQFCHLHKLGSKYILGIAGLFTVFSSFVFSSSVIKFLGSDVSDL---KDALFFFLLLIDLSKATVLAQFALSSQSQDEVKHNIAHGIAMLGPTITLDTVVETLVIGVGTLSGVRRLEVLCCFACMSVIVNYIVFMTFYPACLSLILEL--SRSGRSDW---------PTWHDKSR---------IMQALHEEEKPNPVVQ-----RVKVIMSAGLMLVHAHSRWSFASEGEELPVVNLVNGDSAMTSNSTNDVLLQGYILKWLTMSADHIVILILLLALAVKFVFFEVKDDLTKMRWPGSFARTHSRVLAAEGWVEVSNHPQAEDTVVVPTEH----KSVQTDQDEPISQT-SSCGLLEEESNDALTPCLAPEDRSVEECLAIYQSEAGAR---ALTDSEVMMLITHNHIPSHQLEKAVGNPERGVCIRRKFLNRTAK-LNDALTHLPYQHYDYSKVMGACCENVIGYMPVPVGVAGPLLLDGCLVHVPLATTEGCLVASTNRGSRALMRCG-VSSRIVADGMTRGPVVRFPNISRASEAMLWMQESQNFEAIQDSFNSTSRFARLSRIHIRVAGRHLFIRFVAKTGDAMGMNMLSKGTEVALEFVQETFPDMEVLSLSGNFCTDKKSAAVNWIEGRGKSVVCEAVVPADVVRSILKTTVQALVDVNISKNLIGSAVAGSIGGFNAHAANIVTAIFIATGQDPAQNVGSSNCMTLMEPWGSDGRDLYVSCTMPSIEIGTVGGGTVLPPQAACLEMLGVRGANKRCPGENANRLARIVCGTVLAGELSLMSALAAGHLVKSHLQHNRASVRI 854
BLAST of EMLSAG00000004979 vs. nr
Match: gi|746719580|gb|AJD79560.1| (3-hydroxy-3-methylglutaryl-CoA, partial [Nicrophorus vespilloides]) HSP 1 Score: 646.351 bits (1666), Expect = 0.000e+0 Identity = 377/867 (43.48%), Postives = 513/867 (59.17%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTFVPLDGGSPEWSP-------------------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLYAFLLSM--TAFLLGG--------PDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLITSPQGQAKWNVKRILETLPTQEPPSRTPLRVLAFPVLVLLHLTCLQPPSLQLHIQNTPHIIISLSLVLLSYYFYSNKDEDATS-------LHLRKSYEEAFTRKLQDQDSSVSRLKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAVGK 840
G+ PWEV+ +L + ++T V +P P +V+ V R L++L Y Q +HRLGS +L +AGL+ S T+ +L DA F LLL D+ K L ++ALSA++++ + ++R M L PT+ DT+++ L+ + L +L ++++ VF YP LS+ L L + K ++KR L + E ++ PVL + + + I L +V ++ ++EDA S + L ++ E AF + V+ D + + N ++++ D + MP K ++ + + D +D+ + + + + + P RS+ C+ I + N L DEEV+ L+E+++I ++ +EK ++D RGV +RRK++ + Q A LPYK++DY VMGACCE+V+GY+PVPVG+ GPL LD K +PMATTEGCLVASTNRG AL +CG V S+I DGM+RGPVVRFP++ A +A W+E P NY++IK+SFDS SRFA L ++ +RL GR +Y+RFVAKTGDAMGMNMLSK TE AL + FPEM+I+S+SGN CTDKKPAAVNWIEGRGKSVVCEAIVPA IV+ +LKTS ALVD+N +KN GSA+AGSIGG+NAH+AN+VTAIFIATGQD AQN+GSSNCMTLMEPWG DG+DLYITCTMPSIE+GTIGGGTIL PQ SCLEMLGVKG + PGEN+ QLARI+C VLAGELSLM+AL AG LV SHLRHNRS+ V +
Sbjct: 5 GEFCATHPWEVIVATLMLTVCMLT-VEQQQHAPIPKPTTRSCVGCLNEAEYNAADVIVMTVIRCLAVLYSYYQFCNLHRLGSKYILGIAGLFTVFSSFVFTSTVLNFLRIDFSELKDALFFFLLLIDLSKAAMLAEFALSASNQNEVKSNIARGMSVLGPTITLDTIVETLVIGVGTLSGVHRLEMLSCFACLSVVVNYVVFMTFYPACLSLILELSRTTNLYGKRDIKRSLISRALNEEDQKSN------PVLERVKII----------------MAIGLMIVHAHSWWPFRQEEDAISPLVVEQRMTLNRTDEAAFHGYIMKW---VTLSADHIVILILLLALAVKFIFFENKEELELGARLIETKQDIPEIIMNAAAPMPFFKPKQFFLQNQDI----EDAPQDKEVQTEPVAEVAIKSEPSKPSRSLNECVSIYQSNLG---AAALNDEEVLLLIEKKYIPAYQVEKAVDDCERGVGIRRKMVGHKGNFTQ-ALTNLPYKNYDYSKVMGACCENVIGYLPVPVGVAGPLFLDGKKIFVPMATTEGCLVASTNRGSRALLQCG-VKSRIIADGMTRGPVVRFPSLDHASEAAAWMERPENYEQIKNSFDSXSRFAXLMRIHIRLFGRSLYIRFVAKTGDAMGMNMLSKGTELALKFVRDRFPEMEILSLSGNFCTDKKPAAVNWIEGRGKSVVCEAIVPADIVQNVLKTSVDALVDVNISKNLIGSAVAGSIGGYNAHAANVVTAIFIATGQDPAQNVGSSNCMTLMEPWGKDGRDLYITCTMPSIEIGTIGGGTILPPQASCLEMLGVKGANSEFPGENASQLARIVCATVLAGELSLMAALTAGHLVQSHLRHNRSSTHVSQ 836
BLAST of EMLSAG00000004979 vs. nr
Match: gi|1708251|sp|P54960.1|HMDH_BLAGE (RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase; Short=HMG-CoA reductase >gi|1655537|emb|CAA49628.1| hydroxymethylglutaryl-CoA reductase (NADPH) [Blattella germanica]) HSP 1 Score: 646.351 bits (1666), Expect = 0.000e+0 Identity = 390/886 (44.02%), Postives = 533/886 (60.16%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTF--VPLDGGSPEWSP-------------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLYA-------------FLLSMTAFLLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLITSPQ-GQAKWNVKRILETLPTQEPPSRTPL----RVLAFPVLVLLH----LTCLQPPSLQLHIQNTPHIIISLSLVLLSYYFYSNKDEDATSLHLRKSY----EEAFTRKLQDQDSSVSRLKDDLDRASQSTDEGI-------GLTKSAN-------SASDLKKSKILVVGDDSSSE---SAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLA 837
GQ PWEV+ +LT + ++T PL G P W +V+ + R +++L Y Q + +LGS +L +AGL+ FL S + L DA F LLL D+ K T L Q+ALS+ + + ++R + L PT+ DT+++ L+ + L +L ++++ VF YP LS+ L L S + G+ W+ K ++ +E P+ +V+ L+L+H + CL I+L L S ++ + S + R S+ EE T KL DS V+ S STD+ LT SA+ + K D+ ++ W EV P ++ + QT + S ++ L E +S+ RSI+ CL + K + L+D EV+ LV HI + LEKV+ + RGV +RR+++++ L+ A + LPYK++DY VMGACCE+V+GYMPVPVG+ GPL LD +L H+P+ATTEGCLVASTNRG AL +CG VTS+I DGM+RGPVVRFPN+ A +A W++ P N+++IK +FDSTSRFARL+K+ +R+AGR +++RF+A TGDAMGMNMLSK TE AL + ++P+M+I+S+SGN CTDKKPAAVNWIEGRGKSVVCEAIVPA I++++LKTS AL+D+N KN GSA+AGSIGGFNAH+ANIVTAIFIATGQD AQN+GSSNCMTLMEPWG DGKDLY++CTMPSIE+GTIGGGT+L PQ +CL+MLGV+G + PGEN+ LARI+CG VLAGELSLMSALAAG LV SH+RHNRS+++
Sbjct: 10 GQFCASHPWEVIVATLTLTVCMLTVDQRPL-GLPPGWGHNCITLEEYNAADMIVMTLIRCVAVLYSYYQFCHLQKLGSKYILGIAGLFTVFSSFVFSSSVINFLGSDVSDL---KDALFFFLLLIDLSKATVLAQFALSSRSQDEVKHNIARGIAMLGPTITLDTVVETLVIGVGMLSGVRRLEVLCCFACMSVIVNYVVFMTFYPACLSLILELSRSGESGRPAWHDKSLIIKALHEEDQKPNPVVQRVKVIMSAGLMLVHAHRWVRCLS---------------IALWPDLTSLRYFCTHCDTGVS-YSRWSFASEGEELPTVKLVTGDSVVN---------SNSTDDAQLHYYIMRWLTVSADHIVILILLLALAVKFVFFETRDELTTTRGMDGWVEVSSP-VEHKYVQTEQP------SCSAPEQPLEEPPASN-----------RSIDECLSVCKSDVGAQA---LSDCEVMALVTSGHIAGYQLEKVVRNPERGVGIRRQILTKTAD-LKDALDNLPYKNYDYLKVMGACCENVIGYMPVPVGVAGPLNLDGRLVHVPLATTEGCLVASTNRGMRALMRCG-VTSRIVADGMTRGPVVRFPNIDRASEAMLWMQVPYNFEQIKKNFDSTSRFARLSKIHIRVAGRHLFIRFIATTGDAMGMNMLSKGTEVALAYVQQVYPDMEILSLSGNFCTDKKPAAVNWIEGRGKSVVCEAIVPADIIKSVLKTSVQALMDVNITKNLIGSAVAGSIGGFNAHAANIVTAIFIATGQDPAQNVGSSNCMTLMEPWGEDGKDLYVSCTMPSIEIGTIGGGTVLPPQAACLDMLGVRGANEMCPGENANTLARIVCGTVLAGELSLMSALAAGHLVKSHMRHNRSSVS 843
BLAST of EMLSAG00000004979 vs. nr
Match: gi|859132811|gb|AKO63319.1| (3-hydroxy-3-methylglutaryl coenzyme A reductase 2 [Leptinotarsa decemlineata]) HSP 1 Score: 644.425 bits (1661), Expect = 0.000e+0 Identity = 381/893 (42.67%), Postives = 525/893 (58.79%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTFVPLDGGSPEWSPVVVF-------------------VFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY----AFLLSMTAF------LLGGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXL--ITSPQGQAKWNVKRILETLPTQEPPSRTPLRVLAFPVLVLLHLTCLQPPSLQLHIQNTPHIIISLSLVLLSYYFYSNKDEDATSLH---------------------------LRKSYEEAFTRKLQDQDSSVSRLKDDLDRASQSTDEGIGLTKSANSASD-----LKKSKILVVG----DDSSSESAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRST 835
G+ PWEV+ ++T ++T V +P PV+ F + R L++L Y ++H+LGS +L VAGL+ +F+ + T + DA F LLL D+ K L Q+AL+A+ ++ + + +++ M L PT+ DT+++ L+ + L +L ++L+ VF YP LS+ L L TS + + + + + P ++V+ L+L+H + P + + +I+ + L N+ ED T+LH + E FT K++ S + +++ E + ++ N K S+ +G D+ S +S+ SEV +L+D+ QT S D + LSE+ + + R++E CL I N L DEEV+ LV+ +HI ++ LEK L++ RGV +RRK++S L KA LP++++DY VMGACCE+V+GYMPVPVG GPL LD + ++PMATTEGCLVASTNRGC L K GV S I DGM+RGPVVRFP++S A A W+E P N+ +K+ FD++SRFARL ++ +R+AGR +++RFVAKTGDAMGMNMLSK TE +L + FP+M+I+S+SGN CTDKKPAAVNWIEGRGKSVVCEAI+ A IV +ILKT+ ALVD+N +KN GSAMAGSIGGFNAH+ANIVTAIFIATGQD AQN+GSSNCMTLMEPWG G+DLY++CTMPSIE+GT+GGGT+L Q +CLEMLGVKG + +PGEN+ QLARI+CG VLAGELSLM+ALAAG LV SHLRHNRST
Sbjct: 10 GEFCASHPWEVIVATITLTACMLT-VDQQHPAPPPKPVIRFCTGCLHEAEYNAADVIVMTIIRCLAVLYCYYHFCKLHKLGSKYILSVAGLFTVFSSFIFTTTVLNILRMNVTDLKDALFFFLLLIDLSKAAMLAQFALNASSKTEVKNNIAKGMSVLGPTITLDTVVETLVIGVGTLSGVHRLEMLSCFACLSVLVNYVVFMTFYPACLSLILELSRATSIYAKKQCILSKAFREEDHKSNPVVQRVKVIMSAGLMLVHAHS-RWPFREGDSDDAGSLIVDQHMTL-------NRTED-TALHGYIMKWVTLSADHIVILILLLALVVKFIFFENREEFTEKIRASTS---------ESLEKNSSESFCINQNLNDKFPPEIPVYKPSEKFFLGKSDIDEKSDKSSVSEV---ELEDKAIQT-------SRYDLNEQNLLSENNEE------NVKNSCRTLEECLAIY--NDFDLGAVALNDEEVILLVKHKHIATYQLEKALDNPERGVKIRRKIVSNEANSL-KALTGLPFRNYDYSKVMGACCENVIGYMPVPVGYAGPLLLDGRELYVPMATTEGCLVASTNRGCRTL-KQSGVISSIVGDGMTRGPVVRFPSISKASAAMKWMESPSNFALMKEKFDASSRFARLTRILIRIAGRYLFIRFVAKTGDAMGMNMLSKGTELSLKFVQQEFPDMEIMSLSGNFCTDKKPAAVNWIEGRGKSVVCEAIISAKIVTSILKTNVHALVDVNYSKNMIGSAMAGSIGGFNAHAANIVTAIFIATGQDPAQNVGSSNCMTLMEPWGESGEDLYMSCTMPSIEIGTVGGGTVLPAQAACLEMLGVKGANHDNPGENANQLARIVCGMVLAGELSLMAALAAGHLVKSHLRHNRST 863
BLAST of EMLSAG00000004979 vs. nr
Match: gi|631793759|gb|AHZ20731.1| (HMG-CoA reductase [Diploptera punctata]) HSP 1 Score: 643.654 bits (1659), Expect = 0.000e+0 Identity = 371/856 (43.34%), Postives = 519/856 (60.63%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTFVPLDGG-SPEWSP-------------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLYAFLLSMTAF-----LLGG-----PDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLITSPQG-QAKWNVKRILETLPTQEPPSRTPLRVLAFPVLVLLHLTCLQPPSLQLHIQNTPHIIISLSLVLL---SYYFYSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSRLKDDLDRA-SQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTL 836
GQ PWEV+ + T ++T P G P W +V+ + R +++L Y Q + +LGS +L +AGL+ S LG DA F LLL D+ K T L Q+ALS+ + + ++R + L PT+ DT+++ L+ + L +L ++++ VF YP LS+ L L S +G + W+ + ++ +E P+ +Q +I+S L+L+ S + ++++ E+ ++L T QD +++ D + R + S D + L A ++ + + W EV P ++ + QT + C + SS ++ DE L D R ++ CL I K +A N L+D EV++LV H+ ++ LEK++ D RGV +RRK+++++ L+ A + LPYK++DY VMGACCE+V+GYMPVPVG+ GPL+LD L ++P+ATTEGCLVASTNRG AL +CG VTS+I DGM+RGPVVRFPN+ A +A W++ N++ +K FDSTSR+ARL+K+ +R+AGR +++RFVA TGDAMGMNMLSK TE AL+ + +FP+M+I+S+SGN CTDKKPAAVNWIEGRGKSVVCEA+VPA +V ++LKTS ALVDLN KN GSA+AGS+GG NAH+ANIVTAIFIATGQD AQN+GSSNC+T+MEPWG D KDLY++C+MPSIE+GT+GGGTIL PQ +CL+MLGVKG + PGEN+ LARI+CG VLAGELSLMSALAAG LV SHLRHNRS++
Sbjct: 10 GQFCASHPWEVIVATFTLTACMLTVDPHPLGLPPGWRKNCISLEEYNAADVIVMTLIRCVAVLYSYYQFCHLQKLGSKYILGIAGLFTVFSSFVFSSSVINFLGSDISDLKDALFFFLLLIDLSKATLLAQFALSSCSQDEVKHNIARGIAMLGPTITLDTVVETLVIGVGTLSGVRRLEVLCCFACMSVIVNYIVFMTFYPAFLSLILELARSGEGGRPAWHDRSLIMKALHEEDQKPNPV------------------------VQRV-KVIMSAGLMLVHAHSRWSFASEGEELPIVNLVTGDSVVITNSTQD-----AQIHDYIMRWLTVSADHIVILILLLALAVKFVFFEVKDELNTTRGMDGWVEVSSP-VEHKFVQTDQVCWELPSSSQEPDE---------QPLPCD-----RPVQECLAICKSDAGANS---LSDSEVMSLVSSGHVAAYQLEKMVGDPERGVGIRRKILTQKAD-LKDALDNLPYKNYDYTKVMGACCENVIGYMPVPVGVAGPLKLDGCLVYVPLATTEGCLVASTNRGSRALMRCG-VTSRIVADGMTRGPVVRFPNIERASEAMLWMQAAQNFEAMKKHFDSTSRYARLSKIHIRVAGRHLFIRFVATTGDAMGMNMLSKGTEVALSFVQQMFPDMEILSLSGNFCTDKKPAAVNWIEGRGKSVVCEAVVPADVVSSVLKTSVQALVDLNITKNFYGSAIAGSVGGNNAHAANIVTAIFIATGQDPAQNVGSSNCITIMEPWGDDKKDLYVSCSMPSIEIGTVGGGTILPPQAACLDMLGVKGANAVCPGENANMLARIVCGTVLAGELSLMSALAAGHLVKSHLRHNRSSV 815
BLAST of EMLSAG00000004979 vs. nr
Match: gi|572269797|ref|XP_006612911.1| (PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase-like isoform X1 [Apis dorsata]) HSP 1 Score: 642.884 bits (1657), Expect = 0.000e+0 Identity = 374/831 (45.01%), Postives = 495/831 (59.57%), Query Frame = 0
Query: 55 VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLYAFLLSMTAFLLGG----------PDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLITSPQGQAKWNVKRILETLPTQEP-----PSRTPLRVLAFPVLVLLHLTCL-----QPPSLQLHIQNT-PHIIISLSLVLLSYYFYSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSRL------------KDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVY----MPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSS--HLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAV 838
+V+ + R L++L Y Q + + +LGS +L +AGL+ S+ DA F LL+ D+ K L Q ALS+ ++ + ++R M L PT+ DTL++ LL ++ L +L S +++ VF YP LS+ L L + +I P E P ++++ L ++H +++ + +T H+I++ SY NK ED++ + K Y + D + L K+D+ + Q E K N KK +I V D + S + MP T + +E DE G S+ +L S PRSIE CL I K N LTDEEV+ LV+ HI ++ LEK + D RGV +RR +I L LPYK +DY V+GACCE+V+GY+PVP+G+ GPL LD +LY++PMATTEGCLVASTNRG AL KCG VTS++ DGM+RGPVVRFPN+ A +A W++DP N++E+K+SF+ TSRFARL K+ +R+AGR +++RFVA TGDAMGMNMLSK TE +LN + FP+M+I+S+SGN CTDKKPAAVNW+ GRGKSVVCEA+VPA IV +LKTS ALVD+N +KN GSA+AGSIGGFNAH+ANIVTAIFIATGQD AQN+GSSNCMTLMEPWG DG DLY++CTMPSIE+GT+GGGTIL QG+CL +LGVKG H PGEN+ +LARI+C VLAGELSLM+AL AG LV SHLRHNRS+ V
Sbjct: 65 IVMTIIRCLAILFTYHQFRNLQKLGSKYILGIAGLFTVFSSVVFTSSVVNFGRSDISDLKDALFFFLLIIDLSKAAVLAQLALSSRNKEEVRANIARGMSLLGPTITLDTLVETLLISIGSLSGVRRLEILCSFACLGVVVNYIVFMTFYPACLSLILELSRETNTMKPLSADKIFMMHPLDEEDQKPNPVVERVKLIMIAGLFVVHANSRFKSEESEDTVEGKVSSTNSHVIVN------SY----NKTEDSSEV---KGYLMNWLSVSADNIVILILLLALAIKFIFFEDKEDIAKQLQFKVEDDTEEKIENEYMKEKKFEIEYVKDKENENEDMSFSFLTTKMPFKLSFAKMQTISIPWIDGKEEQIDEKQCTVGISNDKNLFS----RIPRSIEECLKIYKSELGAN---GLTDEEVIQLVKNNHIAAYQLEKAVGDMERGVEIRRFIIGEAGNFLD-YLSNLPYKDYDYSKVLGACCENVMGYVPVPLGIAGPLLLDGELYYVPMATTEGCLVASTNRGSRALLKCG-VTSRVVADGMTRGPVVRFPNIVRASEAMAWMQDPDNFKEMKNSFNLTSRFARLTKINIRIAGRHLFIRFVATTGDAMGMNMLSKGTEKSLNTVKEHFPDMEILSLSGNFCTDKKPAAVNWVCGRGKSVVCEAVVPAEIVTNVLKTSVHALVDVNISKNMIGSAIAGSIGGFNAHAANIVTAIFIATGQDPAQNVGSSNCMTLMEPWGTDGSDLYVSCTMPSIEIGTVGGGTILPAQGACLSILGVKGAHSDEPGENASRLARIVCATVLAGELSLMAALTAGHLVKSHLRHNRSSTTV 873
BLAST of EMLSAG00000004979 vs. nr
Match: gi|91082547|ref|XP_973850.1| (PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase [Tribolium castaneum] >gi|642922803|ref|XP_008193331.1| PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase [Tribolium castaneum] >gi|1004400206|gb|KYB27676.1| 3-hydroxy-3-methylglutaryl-coenzyme A reductase-like Protein [Tribolium castaneum]) HSP 1 Score: 642.884 bits (1657), Expect = 0.000e+0 Identity = 378/881 (42.91%), Postives = 532/881 (60.39%), Query Frame = 0
Query: 18 GQATVKQPWEVLFVSLTSLLSLVTFVPLDGGSPEWSP---------------------VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY----AFLLSMTAFLL------GGPDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXL--ITSPQGQAKWNVKRILETLPTQEPPSRTPLRVLAFPVLVLLHLTCLQPPSLQLHIQNTPHIIISLSLVLLSYYFYSNKDEDATSLH------LRKSYEEAFTRK-----------LQDQDSSVSRLKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVYMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPP--RSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAV 838
G+ PWEV+ +LT ++T +D P P +V+ + R L++L Y Q + +LGS +L +AGL+ +F+ + T L DA F LLL D+ K L Q ALSA+++ + ++R M L PT+ DT+++ L+ + L +L ++L+ VF YP LS+ L L T+ G + + R L+ + P ++++ L+L+H + P + ++N +++ + L N+ ED T+LH + S + ++++ +L+ + +++S D G K L K++ + +++ +SA +D+E QT D R E+ E L +G+ S RS+E CL I N L+D+EV+ LV+ +HI ++ +EK ++D RGV +RRK+++R E + +A LP++++DY VMGACCE+V+GYMPVPVG GPL LD + ++PMATTEGCLVASTNRGC AL CG VTS++ DGM+RGPVVRFP+++ A +A W++ N++ +K FDS+SRFARL+KL +++AGR +++RF AKTGDAMGMNM+SK TE +L + FPEM+I+S+SGN CTDKKPAAVNWIEGRGKSVVCEAI+P+ IV+ +LKTST ALVD+N++KN GSA+AGSIGGFNAH+ANIVTAI+IATGQD AQNIGSSNCMTLMEPWG G+DLY++CTMPSIE+GT+GGGT+L Q SCLEML VKG HP PGEN+ QLARI+CG VLAGELSLM+AL AG LV SHLRHNRST +
Sbjct: 10 GEFCATHPWEVIVATLTLAACMLT---VDQQHPAPPPKPTLRYCAECLQEAEYNAADLIVMTLIRCLAVLYCYYQFCNLEKLGSKYILGIAGLFTVFSSFVFTSTVLNLLWIDVSDLKDALFFFLLLIDLSKAAMLAQSALSASNQEEVKSNIARGMAVLGPTITLDTIVETLVIGVGTLSGVHRLEMLSYFACLSVLVNYIVFMTFYPACLSLILELSRTTNIYGNKQSLIARALKEEDHKSNPVVQRVKLIMSAGLMLVHARS-RWPFKEDDVENIRPLVVEQHMTL-------NRTED-TTLHEYIMKWVTVSADHIVILILLLALVVKFVFFENKEELAEQLRAHI--STESVDPG---KKDNRFKMPLIKTQSFFLTNNTKEDSA--------CEDKEVQT----------DIGRLESEFEK-----LPAGNDVSVKTCRSLEECLKIY--NDSNLGGAALSDDEVILLVKNKHIPAYQIEKAVDDPERGVGIRRKILAR-EGNFSEALTDLPFRNYDYAKVMGACCENVIGYMPVPVGYAGPLNLDGRHVYVPMATTEGCLVASTNRGCRALLDCG-VTSRVVSDGMTRGPVVRFPSITKASEAMSWMKCSQNFEAMKQQFDSSSRFARLSKLLIKIAGRHLFVRFEAKTGDAMGMNMVSKGTEMSLKYVQKQFPEMEILSLSGNFCTDKKPAAVNWIEGRGKSVVCEAIIPSEIVKKVLKTSTPALVDVNNSKNMIGSAVAGSIGGFNAHAANIVTAIYIATGQDPAQNIGSSNCMTLMEPWGETGEDLYVSCTMPSIEIGTVGGGTVLPAQSSCLEMLRVKGSHPDCPGENASQLARIVCGTVLAGELSLMAALTAGHLVRSHLRHNRSTTTI 846
BLAST of EMLSAG00000004979 vs. nr
Match: gi|66501005|ref|XP_623118.1| (PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase isoform X1 [Apis mellifera] >gi|571508657|ref|XP_006571385.1| PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase isoform X1 [Apis mellifera] >gi|1032001175|ref|XP_016773303.1| PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase isoform X1 [Apis mellifera]) HSP 1 Score: 641.728 bits (1654), Expect = 0.000e+0 Identity = 372/844 (44.08%), Postives = 500/844 (59.24%), Query Frame = 0
Query: 55 VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLYAFLLSMTAFLLGG----------PDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLITSPQGQAKWNVKRILETLPTQEP-----PSRTPLRVLAFPVLVLLHLTCL-----QPPSLQLHIQNT-PHIIISLSLVLLSYYFYSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSRL------------KDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSS------------------SESAWSEVYMPDLKDQEAQTTE-ECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAV 838
+V+ + R L++L Y Q + + +LGS +L +AGL+ S+ DA F LL+ D+ K L Q ALS+ ++ + ++R M L PT+ DTL++ LL ++ L +L S +++ VF YP LS+ L L + +I P E P ++++ L ++H +++ + +T H+I++ SY N+ ED++ + K Y + D + L K+D+ + Q E K N KK +I V D + S + + +P + +E Q E +C V +S+D++ L S PRS+E CL I K N LTDEEV+ LV+ HI ++ LEK + D RGV +RR +I L LPYK +DY V+GACCE+V+GY+PVP+G+ GPL LD +LY++PMATTEGCLVASTNRG AL KCG VTS++ DGM+RGPVVRFPN+ A +A W++DP N++E+K+SF+ TSRFARL K+ +R+AGR +++RFVA TGDAMGMNMLSK TE +LN + FP+M+I+S+SGN CTDKKPAAVNW+ GRGKSVVCEA+VPA IV +LKTS ALVD+N +KN GSA+AGSIGGFNAH+ANIVTAIFIATGQD AQN+GSSNCMTLMEPWG DG DLY++CTMPSIE+GT+GGGTIL QG+CL +LGVKG H PGEN+ +LARI+C VLAGELSLM+AL AG LV SHLRHNRS+ V
Sbjct: 65 IVMTIIRCLAILFTYHQFRNLQKLGSKYILGIAGLFTVFSSVVFTSSVVNFGRSDISDLKDALFFFLLIIDLSKAAVLAQLALSSRNKEEVRANIARGMSLLGPTITLDTLVETLLISIGSLSGVRRLEILCSFACLGVVVNYIVFMTFYPACLSLILELSRETNTMKPLSADKIFMMHPLDEEDQKPNPVVERVKLIMIAGLFVVHANSRFKSEESEDTVEGKVSSTNSHVIVN------SY----NETEDSSEV---KGYLMNWLSVSADNIVILILLLALAIKFIFFEDKEDIAKQLQFKVEDDTEEKIENEYMKEKKFEIEYVKDKENENEDMNFSFLTTKMPFKLSFAKMQTISIPWIDGKEEQIDEKQCTVNTSNDKN-------------LFS----QIPRSVEECLKIYKSELGAN---GLTDEEVIQLVKNNHIAAYQLEKAVGDMERGVEIRRFIIGEAGNFLD-YLSNLPYKDYDYSKVLGACCENVMGYVPVPLGIAGPLLLDGELYYVPMATTEGCLVASTNRGSRALLKCG-VTSRVVADGMTRGPVVRFPNIVRASEAMAWMQDPDNFKEMKNSFNLTSRFARLTKINIRIAGRHLFIRFVATTGDAMGMNMLSKGTEKSLNTVKEHFPDMEILSLSGNFCTDKKPAAVNWVCGRGKSVVCEAVVPADIVTNVLKTSVHALVDVNISKNMIGSAIAGSIGGFNAHAANIVTAIFIATGQDPAQNVGSSNCMTLMEPWGTDGSDLYVSCTMPSIEIGTVGGGTILPAQGACLSILGVKGAHSDEPGENASRLARIVCATVLAGELSLMAALTAGHLVKSHLRHNRSSTTV 873
BLAST of EMLSAG00000004979 vs. nr
Match: gi|1035622375|ref|XP_016919153.1| (PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase [Apis cerana] >gi|1035622377|ref|XP_016919154.1| PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase [Apis cerana] >gi|1035622379|ref|XP_016919155.1| PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase [Apis cerana] >gi|1035622381|ref|XP_016919156.1| PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase [Apis cerana]) HSP 1 Score: 640.958 bits (1652), Expect = 0.000e+0 Identity = 370/830 (44.58%), Postives = 497/830 (59.88%), Query Frame = 0
Query: 55 VVVFVFRFLSLLRMYVQLKRIHRLGSAVLLHVAGLYAFLLSMTAFLLGG----------PDAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLLFTL--------LPLLVSSVVFALLLQAFVFAFVYPPLLSIALXLITSPQGQAKWNVKRILETLPTQEP-----PSRTPLRVLAFPVLVLLHLTCL-----QPPSLQLHIQNT-PHIIISLSLVLLSYYFYSNKDEDATSLHLRKSYEEAFTRKLQDQDSSVSRL------------KDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEVY----MP-DLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHSPPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAV 838
+V+ + R L++L Y Q + + +LGS +L +AGL+ S+ DA F LL+ D+ K L Q ALS+ ++ + ++R M L PT+ DTL++ LL ++ L +L S +++ VF YP LS+ L L + +I P E P ++++ L ++H +++ + +T H+I++ SY N+ ED++ + K Y + D + L K+D+ + Q E K N KK +I V D + S + MP L + QT + ++ ++ + D S+ L PRS+E CL I K N LTDEEV+ LV+ HI ++ LEK + D RGV +RR +I L LPYK +DY V+GACCE+V+GY+PVP+G+ GPL LD +LY++PMATTEGCLVASTNRG AL KCG VTS++ DGM+RGPVVRFPN+ A +A W++DP N++E+K+SF+ TSRFARL K+ +R+AGR +++RFVA TGDAMGMNMLSK TE +LN + FP+M+I+S+SGN CTDKKPAAVNW+ GRGKSVVCEA+VPA IV +LKTS ALVD+N +KN GSA+AGSIGGFNAH+ANIVTAIFIATGQD AQN+GSSNCMTLMEPWG DG DLY++CTMPSIE+GT+GGGTIL QG+CL +LGVKG H PGEN+ +LARI+C VLAGELSLM+AL AG LV SHLRHNRS+ V
Sbjct: 65 IVMTIIRCLAILFTYHQFRNLQKLGSKYILGIAGLFTVFSSVVFTSSVVNFGRSDISDLKDALFFFLLIIDLSKAAVLAQLALSSRNKEEVRANIARGMSLLGPTITLDTLVETLLISIGSLSGVRRLEILCSFACLGVVVNYIVFMTFYPACLSLILELSRETNTMKPLSADKIFMMHPLDEEDQKPNPVVERVKLIMIAGLFVVHANSRFKSEESEDTVEGKVSSTNSHVIVN------SY----NETEDSSEV---KGYLMNWLSVSADNIVILILLLALAIKFIFFEDKEDIAKQLQFKVEDDTEEKIENECVKEKKFEIEYVKDKENENEDMSFSFLTTKMPFKLSFAKMQTISIPWIDGKEEQIDEKQCTVDISNDKNL---FSRIPRSVEECLKIYKSELGAN---GLTDEEVIQLVKNNHIAAYQLEKAVGDMERGVEIRRFIIGEAGNFLD-YLSNLPYKDYDYSKVLGACCENVMGYVPVPLGIAGPLLLDGELYYVPMATTEGCLVASTNRGSRALLKCG-VTSRVVADGMTRGPVVRFPNIVRASEAMAWMQDPDNFKEMKNSFNLTSRFARLTKINIRIAGRHLFIRFVATTGDAMGMNMLSKGTEKSLNTVKEHFPDMEILSLSGNFCTDKKPAAVNWVCGRGKSVVCEAVVPADIVTNVLKTSVHALVDVNISKNMIGSAIAGSIGGFNAHAANIVTAIFIATGQDPAQNVGSSNCMTLMEPWGTDGSDLYVSCTMPSIEIGTVGGGTILPAQGACLSILGVKGAHSDEPGENASRLARIVCATVLAGELSLMAALTAGHLVKSHLRHNRSSTTV 873
BLAST of EMLSAG00000004979 vs. Tigriopus kingsejongenis genes
Match: snap_masked-scaffold208_size258758-processed-gene-1.0 (protein:Tk04201 transcript:snap_masked-scaffold208_size258758-processed-gene-1.0-mRNA-1 annotation:"3-hydroxy-3-methylglutaryl- reductase") HSP 1 Score: 767.689 bits (1981), Expect = 0.000e+0 Identity = 430/915 (46.99%), Postives = 581/915 (63.50%), Query Frame = 0
Query: 3 RRPPLKFLEDVSDCLGQATVKQPWEVLFVSLTSLLSLVTF----------------------VPLDGG------SPEWSPVVVFV-FRFLSLLRMYVQLKRIHRLGSAVLLHVAGLY----AFLLSMTAFLLGGP------DAAFSVLLLSDIPKMTQLTQYALSATHESCLPDRLSRAMQTLLPTLLYDTLLKLLL-----FTLLPLLVS---SVVFALLLQAFVFAFVYPPLLSIALXLITSPQGQAKWNVKRILETLPTQEPPSRTPL----RVLAFPVLVLLHLTCLQPPSL---------------QLHIQNTPHIIISLSLVLLS--YYFYSNKDEDATSLHLRKSYEEAFTRKL---QDQDSSVSRLKDDLDRASQSTDEGIGLTKSANSASDLKKSKILVVGDDSSSESAWSEV-YMPDLKDQEAQTTEECLVVSSSDEDRDETLSEDGSSSHLLSGDHHS---PPRSIERCLLILKENAQRNEPCPLTDEEVVTLVEERHIRSHALEKVLNDHLRGVVVRRKLISRREQHLQKAFEKLPYKHFDYHTVMGACCESVVGYMPVPVGLVGPLQLDNKLYHIPMATTEGCLVASTNRGCSALSKCGGVTSQITDDGMSRGPVVRFPNVSAAKKAKDWLEDPVNYQEIKDSFDSTSRFARLNKLKVRLAGRLMYLRFVAKTGDAMGMNMLSKATEFALNKLHFIFPEMQIISISGNMCTDKKPAAVNWIEGRGKSVVCEAIVPASIVETILKTSTAALVDLNSAKNQTGSAMAGSIGGFNAHSANIVTAIFIATGQDAAQNIGSSNCMTLMEPWGPDGKDLYITCTMPSIEVGTIGGGTILAPQGSCLEMLGVKGPHPTSPGENSRQLARIICGAVLAGELSLMSALAAGXLVSSHLRHNRSTLAVGKLA 842
R P F+ + G+ QPWEV+ + L+ ++T +P D S +W +V F L++L + + K+IH + S ++ ++A Y + L ++ + +G P A F + LL D+ K+T++ Q+ALS++H + + ++ M L PT D L K+ L T +P L + V ++++ V+ YP LS+ L L+ G+ +W+V++I+ TLP ++ +TP+ +V+A +L++ H+ +PP L N ++I++ +V LS Y FY + DE + LRK+Y E TRK +Q+ K ++DR S STDEGI + SA S+ GDDSSSESAWSEV Y+PDLKDQEAQTT+ + SS DE D+ E H HH PRS+E C I K E L DEEVV LVE++ IR+HALE VLN+ RGV +RRK + E+ ++ LP+++FDY TVMGACCESV+GYM +PVG+ GPL LD +L+++PMATTEGCLVAS NRGCSAL CG VTS+I DGM+RGP+VRFPN++ +AK+W+E+P N+ +IK +FDSTSRFARL +LK++ AGR +Y+RFVA TGDAMGMNM+SKA EF+L +L +FPEM+++S+SGNMCTDKKPAA+NW++GRGKSV+CEA VP IVET+LKTS AAL DLN +KN GSAMAGSIGGFNA +AN+VTA+FIATGQDAAQN+ SSNC+T ++ G DLY+TCTMPSIEVGT+GGGTIL QG+CL++LGVKG P SPG N++QLA ++C VLAGELSLMSALAAG LV SHLRHNRS LAVG +A
Sbjct: 34 RSLPTLFIRKIFKSHGEFCASQPWEVIVTTFIFLICVLTVGSKHVMMVTEMDSSASSKIKPCLPSDPSCVPEHHSRDWIETLVMAGFYCLAVLHITYRFKKIHLIRSNLIFNIALCYMTFASLLYALIIWSIGNPLKDNLHQAWFLIFLLVDMQKVTRMGQFALSSSHHRRISENVANGMYVLAPTFALDCLAKIFLVGLGSLTRIPQLEAFSWYAVVSVMVNFLVYLTFYPAGLSLVLELMYCTDGRPRWDVRQIINTLPGED--GQTPVVHRVKVVATALLMIAHII-FRPPFLFSSASGISQPTTTLFSWATTNIEKVLITVVIVALSIKYLFYEDMDE---AQELRKTYIEELTRKFAEDSEQEEFNRGNKVEMDRVSNSTDEGISIGSSAKPRPPSCASRH---GDDSSSESAWSEVGYLPDLKDQEAQTTD---MASSEDEVDDDENGEKRRIRH-----HHQLPKEPRSLEECTKIYKGTMDGVEY--LIDEEVVHLVEKKVIRAHALESVLNNPTRGVEIRRKYV---EKVAKRDIGNLPFRNFDYDTVMGACCESVIGYMTMPVGVAGPLNLDGQLFYVPMATTEGCLVASVNRGCSALRTCG-VTSRILADGMTRGPIVRFPNIAKMAEAKEWMEEPENFLQIKSNFDSTSRFARLQRLKLKPAGRELYIRFVAYTGDAMGMNMISKAAEFSLKQLIDVFPEMELVSLSGNMCTDKKPAAINWLDGRGKSVICEATVPGHIVETVLKTSPAALADLNRSKNLVGSAMAGSIGGFNAQAANVVTAVFIATGQDAAQNVASSNCLTQIDVV---GDDLYMTCTMPSIEVGTVGGGTILTAQGACLDLLGVKGCQPASPGANAKQLASVVCATVLAGELSLMSALAAGHLVKSHLRHNRSNLAVGSVA 922 The following BLAST results are available for this feature:
BLAST of EMLSAG00000004979 vs. GO
Analysis Date: 2014-04-02 (Blast vs. GO) Total hits: 25
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BLAST of EMLSAG00000004979 vs. C. finmarchicus
Analysis Date: 2014-05-09 (TblastN vs C. finmarchicus TSA) Total hits: 3
BLAST of EMLSAG00000004979 vs. L. salmonis peptides
Analysis Date: 2014-05-10 (Blastp vs. self) Total hits: 1
BLAST of EMLSAG00000004979 vs. SwissProt
Analysis Date: 2017-02-10 (Blastp vs. SwissProt) Total hits: 25
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BLAST of EMLSAG00000004979 vs. Select Arthropod Genomes
Analysis Date: 2017-02-20 (Blastp vs. Selected Arthropods) Total hits: 14
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BLAST of EMLSAG00000004979 vs. nr
Analysis Date: 2017-02-20 (Blastp vs. NR (2/2017)) Total hits: 25
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BLAST of EMLSAG00000004979 vs. Tigriopus kingsejongenis genes
Analysis Date: 2018-04-18 (Blastp vs. Tigriopus kingsejongensis proteins) Total hits: 1
Alignments
The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Cross References
External references for this gene
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at LSalAtl2s260:1508384..1510927- Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>EMLSAG00000004979-687745 ID=EMLSAG00000004979-687745|Name=EMLSAG00000004979|organism=Lepeophtheirus salmonis|type=gene|length=2544bp|location=Sequence derived from alignment at LSalAtl2s260:1508384..1510927- (Lepeophtheirus salmonis)back to top Add to Basket
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