Query:  540 FNISNDVYY---QPKTQESLKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTI---AHTSPF--LGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRT-----EFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNK 949
            +NISND  Y   +   Q  ++ + G   L+H+ P + LQ P+  T +   + R FHRP +  F  G     T ++       +IK+K +  +  + L    +   +         +   +L E+ EE   +L   GM ++I NYY+RK  +D    K + GE+ +      SPF   G + PG+   A+ N+M+R+P+F+H    +DF+IIR+ T     ++ IR ++ LFV GQ+ P  +VPGP+S++    A++ +++ +YRL  KS D   R+ + ++    P  S+   R+++K   +F +   DS +WV      +P ++ IRS V PE  C   SM   +Q L D GYG        +++DE+T      E ++APW  TR ++LA +GK +L+L G  DPTG  GEGFS+++   K
Sbjct:  452 YNISNDQAYDMLKQNHQNKVRSTLGNVTLEHSMPALRLQWPYYKTELAKAEARSFHRPALS-FRPG----QTCWFKNA---TYIKRKHQKGKDVKTLYNSTKALSL-------ADNSTALLVEYSEEVPVMLSNFGMSNRIINYYRRKNMDDPTRPKAEIGETAVLLPQDKSPFSIFGHVDPGEITPAISNSMYRAPLFQHETKPTDFLIIRSSTGSGGSDYFIRNIENLFVAGQQFPSVDVPGPHSRKVTTVAKNRMKMLVYRLLKKSPD--LRLSISDVTAHIPGTSDMQNRQKVK---DFLQHDKDSKYWVPLEP--VPEQDVIRSWVQPEDVCLLESMQVGQQHLHDTGYGNDAETGGDEDNDEETE---SFEQQMAPWKATRNFLLASQGKAMLKLHGEGDPTG-RGEGFSFIKTSMK 848          

Query:  540 FNISNDVYY---QPKTQESLKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTI---AHTSPF--LGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRT-----EFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNK 949
            +NISND  Y   +   Q  ++ + G   L+H+ P + LQ P+  T +   + R FHRP +  F  G     T ++       +IK+K +  +  + L    +   +         +   +L E+ EE   +L   GM ++I NYY+RK  +D    K + GE+ +      SPF   G + PG+   A+ N+M+R+P+F+H    +DF+IIR+ T     ++ IR ++ LFV GQ+ P  +VPGP+S++    A++ +++ +YRL  KS D   R+ + ++    P  S+   R+++K   +F +   DS +WV      +P ++ IRS V PE  C   SM   +Q L D GYG        +++DE+T      E ++APW  TR ++LA +GK +L+L G  DPTG  GEGFS+++   K
Sbjct:  452 YNISNDQAYDMLKQNHQNKVRSTLGNVTLEHSMPALRLQWPYYKTELAKAEARSFHRPALS-FRPG----QTCWFKNA---TYIKRKHQKGKDVKTLYNSTKALSL-------ADNSTALLVEYSEEVPVMLSNFGMSNRIINYYRRKNMDDPTRPKAEIGETAVLLPQDKSPFSIFGHVDPGEITPAISNSMYRAPLFQHETKPTDFLIIRSSTGSGGSDYFIRNIENLFVAGQQFPSVDVPGPHSRKVTTVAKNRMKMLVYRLLKKSPD--LRLSISDVTAHIPGTSDMQNRQKVK---DFLQHDKDSKYWVPLEP--VPEQDVIRSWVQPEDVCLLESMQVGQQHLHDTGYGNDAETGGDEDNDEETE---SFEQQMAPWKATRNFLLASQGKAMLKLHGEGDPTG-RGEGFSFIKTSMK 848          

Query:  540 FNISNDVYY---QPKTQESLKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTI---AHTSPF--LGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRT-----EFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNK 949
            +NISND  Y   +   Q  ++ + G   L+H+ P + LQ P+  T +   + R FHRP +  F  G     T ++       +IK+K +  +  + L    +   M         +  ++L E+ EE   +L   GM ++  NYY+RK   D    K + GE+ +      SPF   G + PG+    + N+M+R+P+F+H P  +DF+++R+ T     ++ +R ++ L+V GQ+ P  +VPGP+S++    A++ +++ +YRL  KS D   R+ + ++    P  S+   R+++K   +F +   DS +WV      +P  + IRS V PE  C   +M   +Q L D GYG   + A+   D+++       E ++APW  TR ++LA +GK +L+L G  DPTG  GEGFS+++   K
Sbjct:  453 YNISNDQAYDMLKQNHQNKIRSTLGNVTLEHSMPALRLQWPYYKTELAKAEARSFHRPALS-FRPG----QTCWFKN---PAYIKRKHQKGKDAKTLYDSTKALSM-------ADNSNVLLVEYSEESPLMLSNFGMSNRFINYYRRKNMEDSTRPKAEIGETVVLLPQDKSPFSIFGHVDPGEITPTISNSMYRAPLFQHQPRSTDFLVVRSSTGAGGSDYYLRNIEHLYVAGQQFPSVDVPGPHSRKVTTVAKNRMKMLVYRLLKKSPD--MRLSISDVTAHIPGTSDMQNRQKVK---DFLQHDKDSKYWVPLEP--VPESDTIRSWVQPEDVCLLEAMQVGQQHLHDTGYG---IDAETGGDEDEDGEGESFEQQMAPWKATRNFLLASQGKAMLKLHGEGDPTG-RGEGFSFIKTSMK 849          

Query: 1026 GNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFSIGN---KILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEM-KKERRRIQEQLRRIKRNE------EKEKLGLKGNKKLSSKALAKAKKDLKLVCGACGGKGHMRTNKTC 1270
            G+ +++A  Q+ Y    +R++  Q   L S+   S DE++   E E    EDF++   + E                                + TP        + +++D+   S  +  S+ +   K+L+IVR FK E G+   +   V  P VI  YI+ R  K E    +  ++      E+  + ++ ++ +L R+ RN+      EK+K  LK +   S     KA    +  C  CG  GH++TNK C
Sbjct:  873 GHSYNVARQQKSYETSIRRIWDAQKASLSSTVEHSDDESDMDREME----EDFSKPTPHSE--------------------------------APTP--------APNRRDDETTSQFSKMSMADQKGKVLRIVRQFKDERGEIVQKETTVWDPRVIRHYIQHRH-KMEALTTKLESLQPTGDPEIDARNKKLLENELSRLNRNKERRFAREKQKGALKSSTGDSPADGVKAAGTQR-KCANCGQVGHIKTNKKC 1081          

Query:  540 FNISNDVYY---QPKTQESLKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTI---AHTSPF--LGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRT-----EFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNK 949
            +NISND  Y   +   Q  ++ + G   L+H+ P + LQ P+  T +   + R FHRP +  F  G     T ++       +IK+K +  +  + L    +   M         +  ++L E+ EE   +L   GM ++  NYY+RK   D    K + GE+ +      SPF   G + PG+    + N+M+R+P+F+H P  +DF+++R+ T     ++ +R ++ L+V GQ+ P  +VPGP+S++    A++ +++ +YRL  KS D   R+ + ++    P  S+   R+++K   +F +   DS +WV      +P  + IRS V PE  C   +M   +Q L D GYG   + A+   D+++       E ++APW  TR ++LA +GK +L+L G  DPTG  GEGFS+++   K
Sbjct:  453 YNISNDQAYDMLKQNHQNKIRSTLGNVTLEHSMPALRLQWPYYKTELAKAEARSFHRPALS-FRPG----QTCWFKN---PAYIKRKHQKGKDAKTLYDSTKALSM-------ADNSNVLLVEYSEESPLMLSNFGMSNRFINYYRRKNMEDSTRPKAEIGETVVLLPQDKSPFSIFGHVDPGEITPTISNSMYRAPLFQHQPRSTDFLVVRSSTGAGGSDYYLRNIEHLYVAGQQFPSVDVPGPHSRKVTTVAKNRMKMLVYRLLKKSPD--MRLSISDVTAHIPGTSDMQNRQKVK---DFLQHDKDSKYWVPLEP--VPESDTIRSWVQPEDVCLLEAMQVGQQHLHDTGYG---IDAETGGDEDEDGEGESFEQQMAPWKATRNFLLASQGKAMLKLHGEGDPTG-RGEGFSFIKTSMK 849          

Query: 1026 GNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFSIGN---KILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEM-KKERRRIQEQLRRIKRNE------EKEKLGLKGNKKLSSKALAKAKKDLKLVCGACGGKGHMRTNKTC 1270
            G+ +++A  Q+ Y    +R++  Q   L S+   S DE++   E E    EDF++   + E                                + TP        + +++D+   S  +  S+ +   K+L+IVR FK E G+   +   V  P VI  YI+ R  K E    +  ++      E+  + ++ ++ +L R+ RN+      EK+K  LK +   S     KA    +  C  CG  GH++TNK C
Sbjct:  873 GHSYNVARQQKSYETSIRRIWDAQKASLSSTVEHSDDESDMDREME----EDFSKPTPHSE--------------------------------APTP--------APNRRDDETTSQFSKMSMADQKGKVLRIVRQFKDERGEIVQKETTVWDPRVIRHYIQHRH-KMEALTTKLESLQPTGDPEIDARNKKLLENELSRLNRNKERRFAREKQKGALKSSTGDSPADGVKAAGTQR-KCANCGQVGHIKTNKKC 1081          

Query:  537 MDPFNISNDVYYQ-----PKTQESLKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHT---SPF--LGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTR-----TEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKN-NFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAG--YGEKFLFA---------QQDEDDEDTA--------------LKMDD---ELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNK 949
            +D FN+SND  Y+       T++   +S     ++H+ P + LQ P+    +   + R FHRP V     G LM ++                K R+ +++        F++T +        ++  E+ E++ P++   GM SK+ NYY+++  +D    K ++GE+ +      SPF   G + PG+ V  L NNM R+P+F+H P  +DF++IR++      ++ +R ++  F VG   P+ E+P P+S++  N +++ L++ +YR+   +  N  RI + ++ K FP  ++   R+RLK   E+ R G D  +W ++  N  +P+EEEIRSM+ PE      +M   +Q L D    +G++             ++DE +ED                 + DD   E ++APWN +R +++A + K +LQL G  DP+G  G G+S +R   K
Sbjct:  304 LDKFNLSNDNEYELLRRNYNTKQRSHLSN--LTIEHSIPAMRLQTPYYKVRLSKAEARAFHRP-VFHVRPGTLMSFSK--------------LKLRKKKKDKGKSLHEMFVKTTDLTVADTANIITMEYTEQYPPIVSNFGMGSKLINYYRKRSPDDTSRPKAQFGETHVLGVEDRSPFWNFGEVYPGEFVPTLYNNMIRAPIFKHEPRNTDFLLIRSQGAGSHQKYYLRSMNVNFAVGNIFPV-EIPAPHSRKVTNISKNRLKMIVYRVM--NSKNAPRISVKDVSKHFPEQTDMQNRQRLKEFMEYQRQGDDQGFWKVRGMNDVIPSEEEIRSMITPEDSSLMDAMQFGQQALEDMAMLFGDESKLMSNRKRKETEKKDEANEDATETEESRREKERKRNKEQDDIEAEEEMAPWNLSRNFVVANQTKAMLQLNGEGDPSG-IGLGYSMLRATQK 739          

Query:  351 LDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSKTAIPGIK------LQTMQQKRPINGDDTWYSIFPVENEELVYGRWEDEVIWDDGRMPR-LHPKIVSLDPNDDNIILGIPEDIDPSTLPSDEPIRKVKIIQKHVKQSRMLLNRXXXXXXXXXXXXXXXXKIDDMDPFNISNDVYYQPKTQESL-KVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIXXXXXXRESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPE--NDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKPVNKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDG--DHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGXXXXXXXXXXXXXXXXXXXXXXXFNEMGKNLENMLSNKKTSSQFXXXXXXXXXXSLQKMIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXNNFSIGNKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVCGACGGKGHMRTNKTCPKFV-PEFEGISIG-SVAMTEQDEEDLEKQLMENIEE--EELVNVDGTKVKLSAKVLQHADKLRRETVKLKIPXXXXXXXXXXXRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQTDIDSLGAALGVEEXXXXXXXXXXXXXXXIVSAEFIDVGSEEAPGGSMEARHXXXXXXXXXXXXDLQYXXXXXXXXXXXXXX----XXXFTVTVDP---LDQQTPHAED--QVDPLVTMNFYXDNQATAGGE--------------------------------EELEVDENYDPSAFLHNLG 1767
            ++ P +AF MVTQVNWE+D++WNG+DIKHKVL KLNSKTNAAGWVPS+ +RTAGSFSQ      PG+K      L T+ +K P N DDTWYSIFPVENEELVYGRWEDEVIWD   MP+ L P+IVSLDPND+NII+ IP+DIDPSTLP++EP RK+KIIQKHVK+S++LLNR+GIISV+EEESPPPPPK DD D F I ND +Y PK   SL KV+TG +LLQHATP V+L APF+PTH+GPIKLR FHR P+KR+S GPL +Y AF+GV  L KH +K  K R +ERE AGGG+IF MR  +D+SGKDG+LVLFE+IEE+ PL+  VGMCSKIKNYYKRKP+  +DKGP + KYGE T AHTSPFLGTM PGQ+VQA+ENNM+RSP++EH  P +DF++IRTRTEFSIREV+  FV GQECPLYEVPGPNSK+ANNF RDFLQVFIYRLFWKSRDNP+RIKMD+IKKAFPAHSESSIRKRLKPCAEFHRTG DSNWWV+K  FRLPTEEEIRSMVDPE C +++SMIAAEQRL+D+GYG+KF+ AQ  EDD++  LKMDDE+K APW+TTRAY+ AMKGKCLLQLTGPADPTGPA EGFSYV+IPNKP NKEEQE QPKRTVTGTDADLRKLPLKDA+AILR NGVPE+EI  LSRW+VIDVVRTLSTEKVKAGE+G    KFSRGNRFSIAEHQERYR+DCQR+F VQN+VL S E+LSSDEAESS EEE++D++  +E+GKNLENM+ NKKTS+QF REREE+ERR LQK++M    E   K  S         E            N++L+I RTFK   GKE+TRTELVRK LVIETY+KVR TK+EQFIRQFAT+DDQ KEEMKKE+RRIQEQLRRIKRN+EKEK+GL    K   K     K      CGAC   GHMRTNK CPKF   EFEG+  G SVAMT +DEE +EK+L E  +E  E+LVNV+GTKVK S K+L+HA++++R++++LKIP       ++ KR R GT +HCDYL N  Y+P KRRRTDP+ITF++YLE I N+LRVM EA  FL PV+ K + +Y+DVIK PMDLQTIR+N+Q KKYH REEFL D+NQ+V NS+ FNG   I T N+K +MD V+ + +ENED+LMKLEK INPLLDDNDQ ALTYILDNILNEKIK+MQESWPFMKPVNKKQ K YYE +K PMDLETIS K+T ++YHSR +F+ D+ LI+ NSL +NGENS+FT K   ++D    TL  ++DH  +LE  I   Q+ ALEQ D+DSLG +   +  PKKKR + +      +S +FIDVG E +P              +G L +DLQYSSE++ ++  E ++    S  FT+ VD    +DQQ   A D  Q D ++      + QA A GE                                 E +VDENYDP+ F   LG
Sbjct:  309 IEFPPEAFHMVTQVNWEDDIIWNGEDIKHKVLSKLNSKTNAAGWVPSSMSRTAGSFSQR-----PGVKPELQIRLATLGKKLPENDDDTWYSIFPVENEELVYGRWEDEVIWDTENMPKKLEPRIVSLDPNDENIIIAIPDDIDPSTLPNEEPTRKIKIIQKHVKKSKLLLNRAGIISVVEEESPPPPPKNDDRDNFYIGNDEFYLPKEPASLIKVATGGSLLQHATPSVQLSAPFIPTHMGPIKLRQFHRWPIKRYSHGPLSNYIAFHGVQSLYKHQRKMEKWRTAEREEAGGGDIFLMREAKDLSGKDGDLVLFEYIEEYPPLIAFVGMCSKIKNYYKRKPDRIDDKGPKELKYGELTYAHTSPFLGTMIPGQTVQAVENNMYRSPIYEHKFPVTDFIVIRTRTEFSIREVNAYFVTGQECPLYEVPGPNSKKANNFTRDFLQVFIYRLFWKSRDNPRRIKMDDIKKAFPAHSESSIRKRLKPCAEFHRTGPDSNWWVMKPGFRLPTEEEIRSMVDPEQCASFYSMIAAEQRLKDSGYGDKFILAQ--EDDDNDDLKMDDEIKCAPWHTTRAYVQAMKGKCLLQLTGPADPTGPAQEGFSYVKIPNKPTNKEEQEAQPKRTVTGTDADLRKLPLKDAKAILRKNGVPEEEIKKLSRWEVIDVVRTLSTEKVKAGEEGMDSFKFSRGNRFSIAEHQERYREDCQRIFEVQNKVLASDEILSSDEAESSSEEEEEDEDL-DELGKNLENMVQNKKTSTQFQREREEMERRKLQKVMMENKLEKKMKEDSGIKDDDGTIE-----------ANQVLRITRTFKNAQGKEYTRTELVRKSLVIETYVKVRNTKNEQFIRQFATMDDQVKEEMKKEKRRIQEQLRRIKRNQEKEKMGLIKPSKRKEKMKPDLKLK----CGACNQVGHMRTNKACPKFTGEEFEGLPGGRSVAMTLEDEERMEKKLDEEFQENPEDLVNVEGTKVKFSEKILRHAEEIKRKSMQLKIP---KDILKSGKRRRAGTGKHCDYLDNKTYKPIKRRRTDPVITFSSYLETILNELRVMQEAEAFLFPVSSKSVTTYYDVIKRPMDLQTIRDNVQNKKYHSREEFLGDINQMVENSSAFNGEASILTINSKVIMDRVVRRFTENEDRLMKLEKMINPLLDDNDQNALTYILDNILNEKIKTMQESWPFMKPVNKKQVKDYYEKIKQPMDLETISRKITSHKYHSRDDFVKDMRLIFQNSLVFNGENSEFTVKAKILIDTVEDTLVPFADHCESLEANIMVAQQRALEQADLDSLGTSFTDDNEPKKKRKKKKHD----ISNDFIDVGHEASPDAD-----------TGDLMDDLQYSSEDEDDDWDEVEDSQDPSQGFTINVDQTALIDQQQQPAFDYYQDDAVIPETPIFNIQAGANGELYAEPDPSMSFHPSQDPHSAYMDAGYTVDYSVHEEQVDENYDPTEFFTGLG 4607          

Query:    3 NLTGFMFGNVDSSGNLDGDSVLGGLCGTSDVMRGXXXXXXTKELLKDVLS-VKEEEGDLCEGEVVKAEDATDYGDIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVDKETSAERTLDKILLDRSLMPPPSMDKTRGDKSRRP------------LAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFGIKASHRPRIWKGVXXXXXXXDIDNIEEQGSKIKKLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAXXXXXXXXXXXXXXXXXTSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXY 302
            NLT F+FGN+D SG L+ + +          +  + +  +   ++++V S  KE   DL     V+ +DATD+ +       +   + +  S +E    +       ++E  D +  A+   D +L+     PPP   K R   S +P            LA+MLP+K+K++DV+E FPEF+ N VLRFS+LF IK SH+PR WK +KKRR+K+  ++ E+   K KK      W++     P DP AYE   +++FH+ A  +        +        +KGPK TDWR GPA++WYD+L LP    ++ Y
Sbjct: 4845 NLTSFLFGNIDQSGQLEEEFLDESTRRQLGSLGSMLADTNLNNIVEEVSSEAKEGTKDLHPD--VELQDATDFNE-------KAPDAEDFSSIDEMLDVDSSDEDDSDDEDKDTKPKADPNNDSMLMP----PPPPQAKERSPVSEKPPKVEYTGPIVAPLASMLPDKYKDVDVKEFFPEFKENSVLRFSKLFPIKESHKPRTWKALKKRRRKERGEDGEDGEPKEKK---KRGWDY-VVPMPTDPNAYEECQSVRFHKAAEIEKPDDPETVEQKE---PEKKGPKPTDWRWGPAQFWYDMLELPEECPDYDY 5723          

Query: 1402 FLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSE----NEDKLMKLEKAINPLLDDNDQVALTYILDNILNEK-IKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLT 1609
            FL+  + K  P Y+D+I  P+D+  I + I+  +Y   EE L+D   + +N  ++N       ++A  L  +++AK  E      D++ ++++    L     Q  +  + D + + +  K  Q S  F+K  +K +   YY+I+K P+DLE IS K+  N Y +  + ++D  L++ N+ +YN  +S        +  +   T+     HLT
Sbjct: 2613 FLEIPSRKDYPDYYDIITEPIDMNMIEQRIKSNQYKGEEELLADCKLMFSNCRLYNEEGSGIYEDANILERILLAKAREIGVLAGDRMKQIKRKTISL-----QQKVKTLYDTLKDYRDAKGRQLSLIFLKLPSKHEYPDYYDIIKRPIDLEKISSKIRNNMYETMEDAVADFTLVFDNAAKYNEPDSQIYKDAQTLARLAHQTVR----HLT 3224          

Query: 1399 ALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLV---IAKLSENEDKLMKLEKAINPLLD 1497
            +L FL+  +    P Y+D+IK P+DL+ I   I+   Y   E+ ++D   +  N+A +N P+    ++A+ L  L    +  L+E+ D +   + A+  +L+
Sbjct: 2559 SLIFLKLPSKHEYPDYYDIIKRPIDLEKISSKIRNNMYETMEDAVADFTLVFDNAAKYNEPDSQIYKDAQTLARLAHQTVRHLTEDGDGIPDAKAAVGDILN 2864          

Query: 1402 FLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSE----NEDKLMKLEKAINPLLDDNDQVALTYILDNILNEK-IKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENS 1584
            FL+  + K  P Y+D+I  P+D+  I + I+  +Y   EE L+D   + +N  ++N       ++A  L  +++AK  E      D++ ++++    L     Q  +  + D + + +  K  Q S  F+K  +K +   YY+I+K P+DLE IS K+  N Y +  + ++D  L++ N+ +YN  +S
Sbjct:  175 FLEIPSRKDYPDYYDIITEPIDMNMIEQRIKSNQYKGEEELLADCKLMFSNCRLYNEEGSGIYEDANILERILLAKAREIGVLAGDRMKQIKRKTISL-----QQKVKTLYDTLKDYRDAKGRQLSLIFLKLPSKHEYPDYYDIIKRPIDLEKISSKIRNNMYETMEDAVADFTLVFDNAAKYNEPDS 723          

Query: 1399 ALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKL 1470
            +L FL+  +    P Y+D+IK P+DL+ I   I+   Y   E+ ++D   +  N+A +N P+    ++A+ L
Sbjct:  535 SLIFLKLPSKHEYPDYYDIIKRPIDLEKISSKIRNNMYETMEDAVADFTLVFDNAAKYNEPDSQIYKDAQTL 750          

Query: 1402 FLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSE----NEDKLMKLEKAINPLLDDNDQVALTYILDNILNEK-IKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENS 1584
            FL+  + K  P Y+D+I  P+D+  I + I+  +Y   EE L+D   + +N  ++N       ++A  L  +++AK  E      D++ ++++    L     Q  +  + D + + +  K  Q S  F+K  +K +   YY+I+K P+DLE IS K+  N Y +  + ++D  L++ N+ +YN  +S
Sbjct: 1054 FLEIPSRKDYPDYYDIITEPIDMNMIEQRIKSNQYKGEEELLADCKLMFSNCRLYNEEGSGIYEDANILERILLAKAREIGVLAGDRMKQIKRKTISL-----QQKVKTLYDTLKDYRDAKGRQLSLIFLKLPSKHEYPDYYDIIKRPIDLEKISSKIRNNMYETMEDAVADFTLVFDNAAKYNEPDS 1602          

Query: 1394 RVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGP 1459
            R+++   Q L   + KR P Y++ I +PMDL+T+ E IQK +Y +  E   D+  I +N+  FN P
Sbjct:  145 RLLNIVFQLLP--SRKRYPEYYEHISDPMDLKTVAEKIQKGEYKEIPELEKDLQLIFSNARSFNEP 336          

Query: 1399 ALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKL 1470
            +L FL+  +    P Y+D+IK P+DL+ I   I+   Y   E+ ++D   +  N+A +N P+    ++A+ L
Sbjct: 1414 SLIFLKLPSKHEYPDYYDIIKRPIDLEKISSKIRNNMYETMEDAVADFTLVFDNAAKYNEPDSQIYKDAQTL 1629          

Query: 1530 NKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYN 1580
            ++K+   YYE + +PMDL+T++ K+ K +Y    E   D++LI+SN+  +N
Sbjct:  178 SRKRYPEYYEHISDPMDLKTVAEKIQKGEYKEIPELEKDLQLIFSNARSFN 330          

Query: 1525 FMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEE 1603
            F+   +K++   YY+ +  P+ L  I  K+   +Y +      D+E++++N   YN ++S     G K+       LEE
Sbjct:  631 FLSLPSKRELPDYYQTITQPISLNQIRRKIRNGEYPTLQHLGEDLEIMFNNCKTYNRQDSKLWKDGNKLQKFFNTKLEE 867          

Query: 1402 FLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSE----NEDKLMKLEKAINPLLDDNDQVALTYILDNILNEK-IKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENS 1584
            FL+  + K  P Y+D+I  P+D+  I + I+  +Y   EE L+D   + +N  ++N       ++A  L  +++AK  E      D++ ++++    L     Q  +  + D + + +  K  Q S  F+K  +K +   YY+I+K P+DLE IS K+  N Y +  + ++D  L++ N+ +YN  +S
Sbjct:  728 FLEIPSRKDYPDYYDIITEPIDMNMIEQRIKSNQYKGEEELLADCKLMFSNCRLYNEEGSGIYEDANILERILLAKAREIGVLAGDRMKQIKRKTISL-----QQKVKTLYDTLKDYRDAKGRQLSLIFLKLPSKHEYPDYYDIIKRPIDLEKISSKIRNNMYETMEDAVADFTLVFDNAAKYNEPDS 1276          

Query: 1399 ALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKL 1470
            +L FL+  +    P Y+D+IK P+DL+ I   I+   Y   E+ ++D   +  N+A +N P+    ++A+ L
Sbjct: 1088 SLIFLKLPSKHEYPDYYDIIKRPIDLEKISSKIRNNMYETMEDAVADFTLVFDNAAKYNEPDSQIYKDAQTL 1303          

Query: 1525 FMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEE 1603
            F+   +K++   YY+ +  P+ L  I  K+   +Y +      D+E++++N   YN ++S     G K+       LEE
Sbjct:  305 FLSLPSKRELPDYYQTITQPISLNQIRRKIRNGEYPTLQHLGEDLEIMFNNCKTYNRQDSKLWKDGNKLQKFFNTKLEE 541          

Query: 1402 FLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSE----NEDKLMKLEKAINPLLDDNDQVALTYILDNILNEK-IKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENS 1584
            FL+  + K  P Y+D+I  P+D+  I + I+  +Y   EE L+D   + +N  ++N       ++A  L  +++AK  E      D++ ++++    L     Q  +  + D + + +  K  Q S  F+K  +K +   YY+I+K P+DLE IS K+  N Y +  + ++D  L++ N+ +YN  +S
Sbjct: 1273 FLEIPSRKDYPDYYDIITEPIDMNMIEQRIKSNQYKGEEELLADCKLMFSNCRLYNEEGSGIYEDANILERILLAKAREIGVLAGDRMKQIKRKTISL-----QQKVKTLYDTLKDYRDAKGRQLSLIFLKLPSKHEYPDYYDIIKRPIDLEKISSKIRNNMYETMEDAVADFTLVFDNAAKYNEPDS 1821          

Query: 1407 NPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIF---NGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWP-------FMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYN 1580
            N +  P Y+D + NP+D+  I++ ++  +Y   E+  +D   +V+N+ ++     PE    Q  + L+   +  +   ED         +  L D +   L   L+ +    + +   + P       F    ++K+   YYE + +PMDL+T++ K+ K +Y    E   D++LI+SN+  +N
Sbjct:   22 NKRSDPGYYDTVVNPIDIMKIQQKLKTDEYDTMEDLKADFELMVSNTKLYYKRGSPEYRDAQELENLLGKAVGSVMAGEDP--------SQTLGDREDSDLGEFLEELFGAIMTAADSTEPSRLLNIVFQLLPSRKRYPEYYEHISDPMDLKTVAEKIQKGEYKEIPELEKDLQLIFSNARSFN 549          

Query: 1394 RVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGP 1459
            R+++   Q L   + KR P Y++ I +PMDL+T+ E IQK +Y +  E   D+  I +N+  FN P
Sbjct:  364 RLLNIVFQLLP--SRKRYPEYYEHISDPMDLKTVAEKIQKGEYKEIPELEKDLQLIFSNARSFNEP 555          

Query: 1399 ALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKL 1470
            +L FL+  +    P Y+D+IK P+DL+ I   I+   Y   E+ ++D   +  N+A +N P+    ++A+ L
Sbjct: 1633 SLIFLKLPSKHEYPDYYDIIKRPIDLEKISSKIRNNMYETMEDAVADFTLVFDNAAKYNEPDSQIYKDAQTL 1848          

Query: 1525 FMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEE 1603
            F+   +K++   YY+ +  P+ L  I  K+   +Y +      D+E++++N   YN ++S     G K+       LEE
Sbjct:  850 FLSLPSKRELPDYYQTITQPISLNQIRRKIRNGEYPTLQHLGEDLEIMFNNCKTYNRQDSKLWKDGNKLQKFFNTKLEE 1086          

Query: 1402 FLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSE----NEDKLMKLEKAINPLLDDNDQVALTYILDNILNEK-IKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENS 1584
            FL+  + K  P Y+D+I  P+D+  I + I+  +Y   EE L+D   + +N  ++N       ++A  L  +++AK  E      D++ ++++    L     Q  +  + D + + +  K  Q S  F+K  +K +   YY+I+K P+DLE IS K+  N Y +  + ++D  L++ N+ +YN  +S
Sbjct: 1216 FLEIPSRKDYPDYYDIITEPIDMNMIEQRIKSNQYKGEEELLADCKLMFSNCRLYNEEGSGIYEDANILERILLAKAREIGVLAGDRMKQIKRKTISL-----QQKVKTLYDTLKDYRDAKGRQLSLIFLKLPSKHEYPDYYDIIKRPIDLEKISSKIRNNMYETMEDAVADFTLVFDNAAKYNEPDS 1764          

Query: 1420 NPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIF---NGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWP-------FMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYN 1580
            NP+D+  I++ ++  +Y   ++  +D   +V+N+ ++     PE    Q  + L+   +  +   ED         +  L D +   L   L+ +    + +   + P       F    ++K+   YYE + +PMDL+T++ K+ K +Y    E   D++LI+SN+  +N
Sbjct:    4 NPIDIMKIQQKLKTDEYDTMDDLKADFELMVSNTKLYYKRGSPEYRDAQELENLLGKAVGSVMAGEDP--------SQTLGDREDSDLGEFLEELFGAIMTAADSTEPSRLLNIVFQLLPSRKRYPEYYEHISDPMDLKTVAEKIQKGEYKEIPELEKDLQLIFSNARSFN 492          

Query: 1394 RVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGP 1459
            R+++   Q L   + KR P Y++ I +PMDL+T+ E IQK +Y +  E   D+  I +N+  FN P
Sbjct:  307 RLLNIVFQLLP--SRKRYPEYYEHISDPMDLKTVAEKIQKGEYKEIPELEKDLQLIFSNARSFNEP 498          

Query: 1399 ALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKL 1470
            +L FL+  +    P Y+D+IK P+DL+ I   I+   Y   E+ ++D   +  N+A +N P+    ++A+ L
Sbjct: 1576 SLIFLKLPSKHEYPDYYDIIKRPIDLEKISSKIRNNMYETMEDAVADFTLVFDNAAKYNEPDSQIYKDAQTL 1791          

Query: 1525 FMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEE 1603
            F+   +K++   YY+ +  P+ L  I  K+   +Y +      D+E++++N   YN ++S     G K+       LEE
Sbjct:  793 FLSLPSKRELPDYYQTITQPISLNQIRRKIRNGEYPTLQHLGEDLEIMFNNCKTYNRQDSKLWKDGNKLQKFFNTKLEE 1029          

Query: 1407 NPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIF---NGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWP-------FMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYN 1580
            N +  P Y+D + NP+D+  I++ ++  +Y   E+  +D   +V+N+ ++     PE    Q  + L+   +  +   ED         +  L D +   L   L+ +    + +   + P       F    ++K+   YYE + +PMDL+T++ K+ K +Y    E   D++LI+SN+  +N
Sbjct:  307 NKRSDPGYYDTVVNPIDIMKIQQKLKTDEYDTMEDLKADFELMVSNTKLYYKRGSPEYRDAQELENLLGKAVGSVMAGEDP--------SQTLGDREDSDLGEFLEELFGAIMTAADSTEPSRLLNIVFQLLPSRKRYPEYYEHISDPMDLKTVAEKIQKGEYKEIPELEKDLQLIFSNARSFN 834          

Query: 1394 RVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGP 1459
            R+++   Q L   + KR P Y++ I +PMDL+T+ E IQK +Y +  E   D+  I +N+  FN P
Sbjct:  301 RLLNIVFQLLP--SRKRYPEYYEHISDPMDLKTVAEKIQKGEYKEIPELEKDLQLIFSNARSFNEP 492          

Query: 1407 NPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIF---NGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWP-------FMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYN 1580
            N +  P Y+D + NP+D+  I++ ++  +Y   E+  +D   +V+N+ ++     PE    Q  + L+   +  +   ED         +  L D +   L   L+ +    + +   + P       F    ++K+   YYE + +PMDL+T++ K+ K +Y    E   D++LI+SN+  +N
Sbjct:  273 NKRSDPGYYDTVVNPIDIMKIQQKLKTDEYDTMEDLKADFELMVSNTKLYYKRGSPEYRDAQELENLLGKAVGSVMAGEDP--------SQTLGDREDSDLGEFLEELFGAIMTAADSTEPSRLLNIVFQLLPSRKRYPEYYEHISDPMDLKTVAEKIQKGEYKEIPELEKDLQLIFSNARSFN 800          

Query: 1394 RVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGP 1459
            R+++   Q L   + KR P Y++ I +PMDL+T+ E IQK +Y +  E   D+  I +N+  FN P
Sbjct:  267 RLLNIVFQLLP--SRKRYPEYYEHISDPMDLKTVAEKIQKGEYKEIPELEKDLQLIFSNARSFNEP 458          

Query: 1358 EHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQ---FLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENED 1483
            E C  +T  N     R R   L+T       + + L  M   L    FL+PV+P + P+Y D I  PMD+Q++  NI++K+Y   E  L+D   I+ N  IFN P    T  AK ++ +   ++ E E+
Sbjct:  958 ECCLIMTAENM--DTRSRAMRLLTVDQLCTLLKHALARMKSVLNIEPFLKPVDPVQFPAYKDYISCPMDMQSMERNIRRKQYGSTEAMLADCKWILHNCIIFNSPSSKLTSIAKSIVKVCKHEMQEVEN 1338          

Query: 1504 LTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEE 1603
            L  +L + L  ++KS+    PF+KPV+  Q  AY + +  PMD++++   + + QY S    L+D + I  N + +N  +S  T+    I+ V +  ++E
Sbjct: 1033 LCTLLKHAL-ARMKSVLNIEPFLKPVDPVQFPAYKDYISCPMDMQSMERNIRRKQYGSTEAMLADCKWILHNCIIFNSPSSKLTSIAKSIVKVCKHEMQE 1329          

Query:    1 MENLTGFMFGNVDSSGNLDGDSVLGGLCGTSDVMRGLSSLLSTKELLKDVLSVKEEEGDLCEGEVVKAEDATDYGDIEEALSDEDSSSSEGGSENENEAEEEKGPAFGEEEGVDKETSAERTLDKILLDRSLMPPPSMDKTRGDKSRRPLAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFGIKASHRPRIWKGVKKRRKKKDIDNIEEQGSKIKKLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAGDDSNGKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSKTAIPGIKLQTMQQKRPINGDDTWYSIFPVENEELVYGRWEDEVIWDDGRMPRLHPKIVSLDPNDDNIILGIPEDIDPSTLPSDEPIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQESLKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKPVNKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFSIGNKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEKLGLKGNKKLSSKALAKAKKDLKLVCGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQHADKLRRETVKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQTDIDSLGAALGVEEPPKKKRGRPRKKGPKIVSAEFIDVGSEEAPGGSMEARHSEEAEGSGLLEEDLQYSSEEDWEEVVEEDNSSSFTVTVDPLDQQTPHAEDQVDPLVTMNFYXDNQATAGGEEELEVDENYDPSAFLHNLGKQLPTEIKEEDEYIPPPVAAQSAEDENDFGNSTYKEEPVDIKDDLDISDSDDNDEDAIEGSPVNKQSTSHSNVPPPPPLEETPDDDTLWF 1857
            MENLTGFMFGNVDSSGNLDGDSVLGGLCGTSDVMRGLSSLLSTKELLKDVLSVKEEEGDLCEGEVVKAEDATDYGDIEEALSDEDSSSSEGGSENENEAEEEKGPAFGEEEGVDKETSAERTLDKILLDRSLMPPPSMDKTRGDKSRRPLAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFGIKASHRPRIWKGVKKRRKKKDIDNIEEQGSKIKKLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAGDDSNGKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSKTAIPGIKLQTMQQKRPINGDDTWYSIFPVENEELVYGRWEDEVIWDDGRMPRLHPKIVSLDPNDDNIILGIPEDIDPSTLPSDEPIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQESLKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKPVNKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFSIGNKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEKLGLKGNKKLSSKALAKAKKDLKLVCGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQHADKLRRETVKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQTDIDSLGAALGVEEPPKKKRGRPRKKGPKIVSAEFIDVGSEEAPGGSMEARHSEEAEGSGLLEEDLQYSSEEDWEEVVEEDNSSSFTVTVDPLDQQTPHAEDQVDPLVTMNFYXDNQATAGGEEELEVDENYDPSAFLHNLGKQLPTEIKEEDEYIPPPVAAQSAEDENDFGNSTYKEEPVDIKDDLDISDSDDNDEDAIEGSPVNKQSTSHSNVPPPPPLEETPDDDTLWF
Sbjct:    1 MENLTGFMFGNVDSSGNLDGDSVLGGLCGTSDVMRGLSSLLSTKELLKDVLSVKEEEGDLCEGEVVKAEDATDYGDIEEALSDEDSSSSEGGSENENEAEEEKGPAFGEEEGVDKETSAERTLDKILLDRSLMPPPSMDKTRGDKSRRPLAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFGIKASHRPRIWKGVKKRRKKKDIDNIEEQGSKIKKLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAGDDSNGKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSKTAIPGIKLQTMQQKRPINGDDTWYSIFPVENEELVYGRWEDEVIWDDGRMPRLHPKIVSLDPNDDNIILGIPEDIDPSTLPSDEPIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQESLKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKPVNKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFSIGNKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEKLGLKGNKKLSSKALAKAKKDLKLVCGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQHADKLRRETVKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQTDIDSLGAALGVEEPPKKKRGRPRKKGPKIVSAEFIDVGSEEAPGGSMEARHSEEAEGSGLLEEDLQYSSEEDWEEVVEEDNSSSFTVTVDPLDQQTPHAEDQVDPLVTMNFYXDNQATAGGEEELEVDENYDPSAFLHNLGKQLPTEIKEEDEYIPPPVAAQSAEDENDFGNSTYKEEPVDIKDDLDISDSDDNDEDAIEGSPVNKQSTSHSNVPPPPPLEETPDDDTLWF 1857          

Query: 1397 DEALQ----FLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAK-----LSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEK-IKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKI----LDVTRATLEEYSDHLTNLEEKIKEV 1618
            DE +Q    F++  + K  P Y++VI++PMD+ TI   I+   Y   EE+L D+  + AN   +N       ++A  L  ++IAK     LS    +    +K    L  D+  + +  + D + + K +K  Q S  F++  N++    YYE++K P+D E IS K+    Y +  E L+D  L++ N+ ++N  +S      L +    L V R  + E +  +T++ ++++++
Sbjct:  381 DEGVQLVSAFMELPSKKDYPDYYEVIEHPMDMNTINNKIKNGAYKNEEEYLQDMKLMFANCKKYNEERSEIYKDAVTLERVLIAKGREIGLSAGLGRGRPSKKKF--LSSDSKNIKMKALFDALRDYKDVKGRQLSLIFLRLPNQRDFADYYEVIKKPIDFEKISTKIKTYVYDNLEETLADFILMFDNACKFNEPDSQIYKDALTLQSLALKVARE-MNETAGSVTDVAQRVQDI 613          

Query: 1410 RLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENE------DKLMKL-EKAINPLLDDNDQ---VAL--TYILDN--ILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQTDIDSLGAALGVEEPPKKKRGRPRKK 1651
            R P+   +I+       IR+ ++ K+Y K  + ++D+N +  N   +N  +    +   KL  L+ +K+ E +      + + ++ E  ++P  + N     VAL    IL N  ++++  + +Q    FM+  +KK    YYE++++PMD+ TI+ K+    Y +  E+L D++L+++N  +YN E S                 E Y D +T        ++R+ + +     L A LG        RGRP KK
Sbjct:  261 RPPARRQIIRKQYSSAEIRKKLKNKEYGKLSDMVNDMNIMFENCKAYNRSDSQIFKEGVKLQRLMTSKVEEIQSGKVVPNGMTEIKETVVSPHFNSNSTHNIVALKNMRILYNTILIHKDDEGVQLVSAFMELPSKKDYPDYYEVIEHPMDMNTINNKIKNGAYKNEEEYLQDMKLMFANCKKYNEERS-----------------EIYKDAVT--------LERVLIAKGREIGLSAGLG--------RGRPSKK 483          

Query: 1379 LITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFN 1457
            L   +T L  + N     +EA  FL PVN K+ P+Y  VIKNPMD+ TI+  ++   Y  R +F +DV QI AN  IFN
Sbjct: 1487 LTACSTLLSELENS----EEAWPFLYPVNTKQFPTYRKVIKNPMDIATIKRRLEXGXYRXRXDFCNDVRQIFANCEIFN 1561          

Query: 1500 DQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNL 1611
            D  A + +L  + N      +E+WPF+ PVN KQ   Y +++KNPMD+ TI  ++    Y  R +F +D+  I++N   +N ++S     G       R   E     LTN+
Sbjct: 1486 DLTACSTLLSELENS-----EEAWPFLYPVNTKQFPTYRKVIKNPMDIATIKRRLEXGXYRXRXDFCNDVRQIFANCEIFNEDDSPVGKAG----HAMRTFFETRWAELTNI 1588          

Query: 1382 FATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENED 1483
              T L+    +LR +     F++ V+P + P+Y D +  PMDL T+ +NI+KK+Y   E FL+D+  I+ N  IFN      T  AK+L+ +   ++ E E+
Sbjct:  111 LCTLLKHALTRLRNISGVDPFIRSVDPXQFPAYRDYVTCPMDLLTLEKNIRKKQYGSTEAFLADLKWILHNCIIFNSLGSKLTSIAKQLVKICKHEMQEVEN 212          

Query: 1402 FLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSE---NEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQTDI 1628
            F++  + K  P Y+++I NP+D+  I   I+   Y   E+ + D+  +  N   +N       ++A  L  +++ K  E   N        +  N  L    ++    + D    +  K  Q S  F+   N ++   YYE +K P+D E IS K+ +N Y S  E L D  L++ N+ +YN  +S      + +  +   T+   +D  +     I ++  I L   DI
Sbjct:  358 FMEKPSKKDYPDYYEIITNPIDMSMIDAKIKTGVYKSEEDVIQDMKLMFINCRRYNEEGSDIYKDANLLEKVLVTKAREMGINAGPGRGRPRKKNLTLSQKLKILFETLRDY---KDHKGRQLSLIFLXLPNLREFADYYETIKKPIDFEKISGKMKQNAYESVEEALRDFILMFDNACKYNEPDSQIYKDAITLQSLALKTVRGMTDESS---ASISKIPNIGLAVRDI 581          

Query: 1427 IRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLM--------------KLEKAINPL------LDDNDQVALTYILDNILNEKIKS-MQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQTDIDSLGAALGVEEPPKKKRGRPRKK 1651
            IR+ ++  +Y +  +   D+N +  N   +N P+    +  +KL  ++ AKL E E +                +L+++ N L         N +  +  + + +LN K +  +     FM+  +KK    YYEI+ NP+D+  I  K+    Y S  + + D++L++ N  +YN E SD                  Y D   NL EK+            + +    +G+   P   RGRPRKK
Sbjct:  239 IRKKMKAGEYAQLVDLADDLNTMFENCKTYNRPDSRLFKEGQKLQKIMHAKLEELEAREDEEDEVEEDEEGESSRLDESGNSLEGRPRSQRANTRKRMRSLYNAVLNFKTEDELSLVGMFMEKPSKKDYPDYYEIITNPIDMSMIDAKIKTGVYKSEEDVIQDMKLMFINCRRYNEEGSDI-----------------YKD--ANLLEKV------------LVTKAREMGINAGP--GRGRPRKK 451          

Query: 1512 LNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKI 1615
            L +++ S + SWPF +PV+      YY +VK PMDL+TI L+V ++QY    +F+ D+  I+ N   +N +NS       ++L    +    ++  L ++ EK+
Sbjct: 2489 LVKQLISNRNSWPFKEPVDPNDVPNYYTVVKEPMDLQTIELRVNQSQYQRLSDFVGDVMRIFENCRYFNQDNS-------QVLRCAESLENYFAQKLAHVREKV 2585          

Query: 1402 FLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKL 1485
            F +PV+P  +P+Y+ V+K PMDLQTI   + + +Y +  +F+ DV +I  N   FN       + A+ L +    KL+   +K+
Sbjct: 2502 FKEPVDPNDVPNYYTVVKEPMDLQTIELRVNQSQYQRLSDFVGDVMRIFENCRYFNQDNSQVLRCAESLENYFAQKLAHVREKV 2585          

Query: 1503 ALTYILDNILNEKIKSMQESWPFMKPVNKKQNKA--YYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNL 1611
            A   IL  I ++K   +  +WPF KPV+        Y +++KNPMDL TI  K+    Y+S  EF +D+ LI++N  +YN    +      K+ DV      +  D   NL
Sbjct:  289 ACNEILKEIFSKK--HVGYAWPFYKPVDTDYLDLHDYDKVIKNPMDLGTIKNKMDNRSYNSAQEFAADVRLIFTNCFKYNPPEHEVVAMARKLQDVFEMKFSKIPDDSGNL 397          

Query: 1399 ALQFLQPVNPKRL--PSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENED 1483
            A  F +PV+   L    Y  VIKNPMDL TI+  +  + Y+  +EF +DV  I  N   +N PE      A+KL D+   K S+  D
Sbjct:  306 AWPFYKPVDTDYLDLHDYDKVIKNPMDLGTIKNKMDNRSYNSAQEFAADVRLIFTNCFKYNPPEHEVVAMARKLQDVFEMKFSKIPD 392          

Query: 1516 IKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDF 1586
            +K+ Q +WPF+ PV+KK    YY+ VK PMDL T++ ++    Y ++  F++D   ++SN   YN  ++++
Sbjct:  679 VKNHQSAWPFLSPVDKKVVNDYYDHVKYPMDLRTMTERLKSLYYCNKRLFIADFRRMFSNCRAYNAPDTEY 749          

Query: 1381 TFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSEN 1481
            TF T L G+ N       A  FL PV+ K +  Y+D +K PMDL+T+ E ++   Y  +  F++D  ++ +N   +N P+  +   A  L   + +KL ++
Sbjct:  671 TFKTILTGVKNH----QSAWPFLSPVDKKVVNDYYDHVKYPMDLRTMTERLKSLYYCNKRLFIADFRRMFSNCRAYNAPDTEYYNCANILEKYLNSKLKDH 767          

Query: 1522 SWPFMKPVNKKQNKA--YYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDV 1596
            +WPF KPV+ KQ     Y++I+K PMDL T   K+   +Y +  EF  DI +I+ N  +YN +  D  +   K+ +V
Sbjct:  318 AWPFYKPVDAKQLGLHDYHDIIKEPMDLGTAKAKMDSREYRTTGEFAHDIRVIFENCFKYNPDTHDIVSMARKLSEV 394          

Query: 1505 TYILDNILNEKIKSMQESWPFMKPVN--KKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFT 1587
            T  L N+L + +     SWPF  PV+  K     Y++I+  PMDL TI  ++  N Y S  E + DI L+++N   YN    D T
Sbjct:   74 TQFLKNVLMKGMWKHTHSWPFQSPVDTIKLGLPDYFKIILKPMDLGTIRKRLENNYYWSGQECIDDINLMFTNCYLYNKSGEDVT 158          

Query: 1402 FLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDL---VIAKLSENEDKLMKLEKAI--NPLLDDNDQVA----------LTYILDNILNEK----------IKSMQE--SWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYN 1580
            F  PV+    P YF  ++ PMDL  I+  +    Y +      D+  I  N+  FN P+    +NAK L+ L   +I    +N+D + ++   +  N L   +D+ A          LT      LN K           K++ +  S PF  PV++ +   Y+  +  PMDL ++   +    ++S  +F  DI L+ SNS  +N
Sbjct: 1097 FNYPVDQSIYPEYFYSVEYPMDLNLIKARVDNNFYRRIASIEYDLKYIFENAEAFNVPKSDIVKNAKILVRLAGEIINDPGKNKDNVSEIYHNLVQNFLWSSSDEDAVEENPRVKKLLTKNSSESLNPKKWKQDCDDLLTKTLDQPFSGPFRGPVSEIEFPDYHRFIVTPMDLSSVRESLMIGNFNSPVDFQKDIHLMISNSRVFN 1302          

Query:    3 NLTGFMFGNVDSSGNLDGDSVLGGLCGT---SDVMRGLSSL--LSTKELLKDVLSVKEEE------------------------------GDLCEGEVVKAED-ATDYGDIEEALSDEDSSSSEGGSENENEAEEEKGPAFGEEEGVDKETSAERTLDKILLDRSLMPPPSMDKTRG---------------------------DKSRR---PLAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFGI-KASHRPRIWKGV-------KKRRKKKDIDNIEEQGSKIKKLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAGDDSNGKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSKTAIP-------------GIKLQTMQQKRPING-DDTWYSIFPVENEELVYGRWEDEVIWDDGRMPRL-HPKIVSLDPNDDNIILGIPEDIDPSTL-PSDEPIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQESLKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKPV-NKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFSIGNKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEKLG-LKGNKKLS-------------------------------SKALAKAKKDLKLVCGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQH--ADKLRRET-----VKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQT----------------------------DID--------------SLGAALGVEE---------PP-----KKKRGRPRK-KGP--KIVSAEFIDVGSEEAPGGSMEARHSEEAEGSGLLEEDLQYSS-------EEDWEEVVEEDNSSSFTV---------------TVDPLDQQT------------PHAEDQ----VDPLVTMNFYXDNQATAGGEEELEVDENYDPSAFL--HNLGKQL--PTEIK---------EEDEYIP--PPVAAQSAEDENDFGNST------YKEEPVD-------IKDDLDISDSDDNDE 1822
            +LTG +FGN+DS G L  D    G  GT   +++   + SL  L    +L +V+ +KE E                              G   E   VKA+D A DY DI E   D   +  E  S  ++   E+  PA   E  + K+            D+ LMPPPS     G                           D  R+   PLA +LP K++ +DVRELFP+FR  KVLRFSRLFG  K +  P+IW+ V        + R +K  +          +      +  +YA  P   E    D           D N ++   +G     +S + PK  DWR GPA+ WYD+L +P   + F Y     AAS     ++ ++KD+R  ++ E+  E      +PS         + DDAF MV+Q++WE+DVVW+G+DIK KVLQKLNSKTNAAGW+PS+ +RTAG+FSQ  K ++P               K Q   Q +P    DDTWYS+FPVENEEL+Y +WEDEVIWD  ++ ++  PK+++LDPND+NIILGIP+DIDPS +  S  P  K+KI   HVK+S++LL ++G+I+V+ E++PPPPPK  D DPFNISND YY PKT+ +L++  G  L+QH+TPVVEL+APFVPTH+GP+KLR FHRPP+K++S GP M  +  + V PL K I KKAK RE ER  +GGG++FFMR PED+SG+DG++VL EF EEH PL++ VGMCSKIKNYYKRK E D GP  F YGE   AHTSPFLG + PGQ +QA+ENNM+R+P++ H    +DF++IRTR  + IR V+ ++ VGQECPLYEVPGPNSKRANNF RDFLQVFIYRLFWKSRDNP+RI+MD+IK+AFPAHSESSIRKRLK CA+F RTG DSNWWVIK  FRLP+EEEIR+MV PE CCAYFSMIAAEQRL+DAGYGEKFLFA Q++DDE+  LK+DDE+KVAPWNTTRAYI AM+GKCLLQL+GPADPTG  GEGFSYVR+PNKP   KEEQE QPKR+VTGTDADLR+LPL+ A+ +LR   VPE+EI  LSRW+VIDVVRTLSTEK KAGE+G  KFSRGNRFSIAEHQERY+++CQR+F +QNRVL SSEVLS+DEAESS  EE        E+GKNLENMLSNKKTS+Q L    E   R      + E    P  SG   G+K K D   +  + N     +IL+I RTF+  DGKE+TR E VR+  VI+ YIK+R TKDEQFI+QFAT+D+QQKEEMK+E+RRIQEQLRRIKRN+E+E+L  L  N+KL                                S+   K K DLKL CGACG  GHMRTNK CP +      +S  + ++ +  +E  EK++   +++++LVNVDGTKV LS+K+L+    D  +R +       LK+P+ A+     KK+ R G   HCDYL   N + A RRRTDP++  ++ LE IHN+LR M +   FL PV+ K++P Y+ V+  PMDLQT+RE I++++Y  RE FL D+ QIV NS I+NGP+  +T  A+++       L+E EDKLM+LEKAINPLLDD+DQVAL++I D  L+ +IK + ESWPF+KPVNKKQ K YY ++K PMDLETI   +  ++YHSR E+L+DIELI +N  QYNG ++ +T    KIL+  +  L E+S+H   LE  I + Q  A E                              D++              S+GA  G            PP     K+ RGRPRK + P  ++ S   +  G       S+ +  S     +  L+EDLQ S+       EED++EV E++N+++  +                 DP + +T            P  ED      + +V ++      A    +E ++VD NYDPS FL  H   + L  P+ ++         E+D+  P  P  A+ SA    D G           E PV+       I DDLDIS+SD+ D+
Sbjct:   19 DLTGILFGNIDSEGRLLQDDDGEGRGGTGFDAELRENIGSLSKLGLDSMLLEVIDLKEAEPPSDDEEEEDARPSAVSASEGMSAFDALKAGVKREDGAVKAQDDAIDYSDITELSEDCPRTPPEETSTYDDL--EDAIPASKVEAKLTKD------------DKELMPPPSAPMRSGSGGGIEEPAKSNDASSPSDDSKSTDSKDADRKLDTPLADILPSKYQNVDVRELFPDFRPQKVLRFSRLFGPGKPTSLPQIWRHVRKRRRKRNQSRDQKTTNTGGSDSPSDTEEPRKRGFSLHYAAEPTPAECMSDDEDKLL-----GDFNSEDVRPEGPDNGENSDQKPKVADWRFGPAQIWYDMLEVPDSGEGFNYGFKTKAASTS---SQPQLKDERRVKSPEDDVE------DPS---------IADDAFLMVSQLHWEDDVVWDGNDIKAKVLQKLNSKTNAAGWLPSSGSRTAGAFSQPGKPSMPVGSGSSKQGSGASSKKAQQNAQAKPAEAPDDTWYSLFPVENEELIYYKWEDEVIWDAQQVSKVPKPKVLTLDPNDENIILGIPDDIDPSKINKSTGPPPKIKIPHPHVKKSKILLGKAGVINVLAEDTPPPPPKSPDRDPFNISNDTYYTPKTEPTLRLKVGGNLIQHSTPVVELRAPFVPTHMGPMKLRAFHRPPLKKYSHGP-MAQSIPHPVFPLLKTIAKKAKQREVERIASGGGDVFFMRNPEDLSGRDGDIVLAEFCEEHPPLINQVGMCSKIKNYYKRKAEKDSGPQDFVYGEVAFAHTSPFLGILHPGQCIQAIENNMYRAPIYPHKMAHNDFLVIRTRNNYWIRSVNSIYTVGQECPLYEVPGPNSKRANNFTRDFLQVFIYRLFWKSRDNPRRIRMDDIKQAFPAHSESSIRKRLKQCADFKRTGMDSNWWVIKPEFRLPSEEEIRAMVSPEQCCAYFSMIAAEQRLKDAGYGEKFLFAPQEDDDEEAQLKLDDEVKVAPWNTTRAYIQAMRGKCLLQLSGPADPTG-CGEGFSYVRVPNKPTQTKEEQESQPKRSVTGTDADLRRLPLQRAKELLRQFKVPEEEIKKLSRWEVIDVVRTLSTEKAKAGEEGMDKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLASSEVLSTDEAESSASEESDL----EELGKNLENMLSNKKTSTQ-LSREREELERQELLRQLDEEHGGPSGSGGAKGAKGKDDPGQQMLATNNQ--GRILRITRTFRGNDGKEYTRVETVRRQPVIDAYIKIRTTKDEQFIKQFATLDEQQKEEMKREKRRIQEQLRRIKRNQERERLAQLAQNQKLQPGGMPTSLGDPKSSGGHSHKERDSGYKEVSPSRKKFKLKPDLKLKCGACGQVGHMRTNKACPLYSGMQSSLSQSNPSLADDFDEQSEKEM--TMDDDDLVNVDGTKVTLSSKILKRHGGDDGKRRSGSSSGFTLKVPRDAM----GKKKRRVGGDLHCDYLQRHN-KTANRRRTDPVVVLSSILEIIHNELRSMPDVSPFLFPVSAKKVPDYYRVVTKPMDLQTMREYIRQRRYTSREMFLEDLKQIVDNSLIYNGPQSAYTLAAQRMFSSCFELLAEREDKLMRLEKAINPLLDDDDQVALSFIFDK-LHSQIKQLPESWPFLKPVNKKQVKDYYTVIKRPMDLETIGKNIEAHRYHSRAEYLADIELIATNCEQYNGSDTRYTKFSKKILEYAQTQLIEFSEHCGQLENNIAKTQERARENAPEFDEAWGNDDYNFDRGSRASSPGDDYIDVEGHGGHASSSNSIHRSMGAEAGSSHTAPAVRKPAPPGPGEVKRGRGRPRKQRDPVEEVKSQNPVKRGRGRPRKDSLASNMSHTQ--AYFLDEDLQCSTDDEDDDEEEDFQEVSEDENNAASILDQGERINAPADAMDGMFDPKNIKTEIDLEAHQMAEEPIGEDDSQQVAEAMVQLSGVGGYYAQQQQDESMDVDPNYDPSDFLAMHKQRQSLGEPSSLQGAFTNFLSHEQDDNGPYNPAEASTSAASGADLGMDASMAMQMAPEMPVNTMNNGMGIDDDLDISESDEEDD 2037          

Query:  149 PLAAMLPEKFKEM--DVRELFPEFRANKVLRFSRLFGIKASHRPRIWKGVKKRRKKKDIDNIEEQGSKIKKLKMS--------HAWEFNYADFPEDPEAYEVDAAIKFHRPAGDDSNGKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSKTAIPGIKLQTMQQKRPINGDDTWYSIFPVENEELVYGRWEDEVIWDDGRMPRL-HPKIVSLDPNDDNIILGIPEDIDPSTLPSDEPIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQESLKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKPV-NKEEQEQQP-KRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFSIGNKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEKLGLKGNKKLSSKALAKAKKDLKLVCGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQHADKLRRETVKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKI 1615
            PLA ++     ++   V ELFPEFR  KVLRF RLFG    + P +W+  +++RKKK  + I+E+  +I++++ S          W ++YA  P  PE    D  I    P     +   G+ D   K T ++  P+  +WR GPA  WYD+L +P     F Y                     R+ E E   K + I      EE  G+ L + D+ F MVTQ++WE+D++W+G+D+KHK  +    + + AGW+PS+  R A +++     A              ++ D  WYSIFP++NE+LVYGRWED +IWD   MPRL  P +++LDPND+N+IL IP++ + +T  S+ P ++ K  +  +K+SR+LL ++G   VI+EE      + +  DP+N+SND YY PK Q+ L+ + G  ++QH+ P VEL+ PF PTH+GPIKLR FHRPP+K++S G L      + V PL KHIKKKAK RE ER+ +GGGE+FFMRTP+D++GKDG+L+L E+ EE+ PL+  VGM +KIKNYYKRKP  D G    KYGE+   HTSPFLG++ PGQ +QA ENN+FR+P++ H  P +DF+IIRTR  + IRE+  +FVVGQ+CPL+EVPGPNSKRAN   RDFLQVFIYRLFWKS+D P+RI+M++IKKAFP+HSESSIRKRLK CA+F RTG DSNWWV+K++FRLPTEEEIR+MV PE CCAY+SMIAAEQRL+DAGYGEK  FA ++E++ED  +K+DDE++ APWNTTRA+I AMKGKCLL++TG ADPTG  GEGFSYV+IPNKP   K+++E QP K+TVTGTDADLR+L LK+A+ +LR  GVPE+EI  LSRW+VIDVVRT+STE+ ++GE    KF+RG+RFS+AEHQERY+++CQR+F +QN+VL S+EVLS+D   SS E     D DF EMGKN+ENML NKKTSSQ  REREE ER+ LQ+M++  GS       +  G+  + D+    +S N S   + LKI RTF+ E+GKE+ R E VRKP VI+ Y+++R TKDE+FIR+FA  D+Q +EEM+KERRRIQEQLRR+KRN+EKEK               K + DLKL CGACG  GHMRTNK CP +  +        VAMTE+ EE+LEK ++ N + EEL+ V+GTK+ L  ++++ AD++RR+++ LK PKQ   Q   KK+ R GT  HCDYL N  ++   RRRTDP++T ++ LE I N +R +     F  PVN K +  Y+ +I  PMDLQT+REN++K+ Y  REEF   +  IV NSA +NGP+   TQ ++ ++DL   KL E EDKL +LEKAINPLLDD+DQVA ++ILDNI+ +K+ ++ +SWPF  PVNKK    YY+++ NPMDLETI   ++K++Y SR  FL D+ LI +NS++YNG  S +T    +I++V   TL EY +HLT LE+ I
Sbjct:  210 PLAGIMQHDATKLLPSVTELFPEFRPGKVLRFLRLFG-PGKNVPSVWRSARRKRKKKHRELIQEE--QIQEVECSVESEVSQKSLWNYDYAP-PPPPEQCLSDDEITMMAPVESKFSQSTGDID---KVTDTK--PRVAEWRYGPARLWYDMLGVPEDGSGFDYGFKL-----------------RKTEHEPVIKSRMIEEFRKLEENNGTDL-LADENFLMVTQLHWEDDIIWDGEDVKHKGTKP--QRASLAGWLPSSMTRNAMAYNVQQGFAAT------------LDDDKPWYSIFPIDNEDLVYGRWEDNIIWDAQAMPRLLEPPVLTLDPNDENLILEIPDEKEEAT--SNSPSKESKK-ESSLKKSRILLGKTG---VIKEEPQQNMSQPEVKDPWNLSNDEYYYPK-QQGLRGTFGGNIIQHSIPAVELRQPFFPTHMGPIKLRQFHRPPLKKYSFGAL-SQPGPHSVQPLLKHIKKKAKMREQERQASGGGEMFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATKIKNYYKRKPGKDPGAPDCKYGETVYCHTSPFLGSLHPGQLLQAFENNLFRAPIYLHKMPETDFLIIRTRQGYYIRELVDIFVVGQQCPLFEVPGPNSKRANTHIRDFLQVFIYRLFWKSKDRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAMVSPEQCCAYYSMIAAEQRLKDAGYGEKSFFAPEEENEEDFQMKIDDEVRTAPWNTTRAFIAAMKGKCLLEVTGVADPTG-CGEGFSYVKIPNKPTQQKDDKEPQPVKKTVTGTDADLRRLSLKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQARSGEGPMSKFARGSRFSVAEHQERYKEECQRIFDLQNKVLSSTEVLSTDTDSSSAE-----DSDFEEMGKNIENMLQNKKTSSQLSREREEQERKELQRMLLAAGS-------AASGNNHRDDDTASVTSLNSSATGRCLKIYRTFRDEEGKEYVRCETVRKPAVIDAYVRIRTTKDEEFIRKFALFDEQHREEMRKERRRIQEQLRRLKRNQEKEK---LKGPPEKKPKKMKERPDLKLKCGACGAIGHMRTNKFCPLYY-QTNAPPSNPVAMTEEQEEELEKTVIHN-DNEELIKVEGTKIVLGKQLIESADEVRRKSLVLKFPKQ---QLPPKKKRRVGTTVHCDYL-NRPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHLTQLEKDI 1618          

Query:  149 PLAAMLPEKFKEM--DVRELFPEFRANKVLRFSRLFGIKASHRPRIWKGVKKRRKKKDIDNIEEQGSKIKKLKM------SHAWEFNYADFPEDPEAYEVDAAIKFHRPAGDDSNGKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSKTAIPGIKLQTMQQKRPINGDDTWYSIFPVENEELVYGRWEDEVIWDDGRMPR-LHPKIVSLDPNDDNIILGIPEDIDPSTLPSDEPIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQESLKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKPV-NKEEQEQQP-KRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFSIGNKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEKLGLKGNKKLSSKALAKAKKDLKLVCGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQHADKLRRETVKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKI 1615
            PLA ++     ++   V ELFPEFR  KVLRF RLFG    + P +W+  +++RKKK  + I+E+  + ++  +         W ++YA  P  PE    D  I    P     +   G+ D   K   ++  P+  +WR GPA  WYD+L +P     F Y                     R+ E E   K K +      EE  G  L + D+ F MVTQ++WE+D++W+G+D+KHK  +    + + AGW+PS+  R A +++     A              ++ D  WYSIFP++NE+LVYGRWED +IWD   MPR L P +++LDPND+N+IL IP++ + +T  S+ P ++ K  +  +K+SR+LL ++G   VI+EE      + +  DP+N+SND YY PK Q+ L+ + G  ++QH+ P VEL+ PF PTH+GPIKLR FHRPP+K++S G L      + V PL KHIKKKAK RE ER+ +GGGE+FFMRTP+D++GKDG+L+L E+ EE+ PL+  VGM +KIKNYYKRKP  D G    KYGE+   HTSPFLG++ PGQ +QA ENN+FR+P++ H  P +DF+IIRTR  + IRE+  +FVVGQ+CPL+EVPGPNSKRAN   RDFLQVFIYRLFWKS+D P+RI+M++IKKAFP+HSESSIRKRLK CA+F RTG DSNWWV+K++FRLPTEEEIR+MV PE CCAY+SMIAAEQRL+DAGYGEK  FA ++E++ED  +K+DDE++ APWNTTRA+I AMKGKCLL++TG ADPTG  GEGFSYV+IPNKP   K+++E QP K+TVTGTDADLR+L LK+A+ +LR  GVPE+EI  LSRW+VIDVVRT+STE+ ++GE    KF+RG+RFS+AEHQERY+++CQR+F +QN+VL S+EVLS+D   SS E     D DF EMGKN+ENML NKKTSSQ  REREE ER+ LQ+M++  GS       +  G+  + D+    +S N S   + LKI RTF+ E+GKE+ R E VRKP VI+ Y+++R TKDE+FIR+FA  D+Q +EEM+KERRRIQEQLRR+KRN+EKEK               K + DLKL CGACG  GHMRTNK CP +  +        VAMTE+ EE+LEK ++ N + EEL+ V+GTK+ L  ++++ AD++RR+++ LK PKQ   Q   KK+ R GT  HCDYL N  ++   RRRTDP++T ++ LE I N +R +     F  PVN K +  Y+ +I  PMDLQT+REN++K+ Y  REEF   +  IV NSA +NGP+   TQ ++ ++DL   KL E EDKL +LEKAINPLLDD+DQVA ++ILDNI+ +K+ ++ +SWPF  PVNKK    YY+++ +PMDLETI   ++K++Y SR  FL D+ LI +NS++YNG  S +T    +I++V   TL EY +HLT LE+ I
Sbjct:  205 PLAGIMQHDATKLLPSVTELFPEFRPGKVLRFLRLFG-PGKNVPSVWRSARRKRKKKHREPIQEEQIQEEECSVELEVNQKSLWNYDYAP-PPPPEQCLSDDEITMMAPVESKFSQSTGDTD---KVMDTK--PRVAEWRYGPARLWYDMLGVPEDGSGFDYGFKM-----------------RKTEHEPAIKCKMMTKLRKLEESNGIDL-LADENFLMVTQLHWEDDIIWDGEDVKHKGTKP--QRASLAGWLPSSMTRNAMAYNVQQGFAAT------------LDDDKPWYSIFPIDNEDLVYGRWEDNIIWDAQAMPRILEPPVLTLDPNDENLILEIPDEKEEAT--SNSPSKENKK-ESSLKKSRILLGKTG---VIKEEPQQNMSQPEVKDPWNLSNDEYYYPK-QQGLRGTFGGNIIQHSIPAVELRQPFFPTHMGPIKLRQFHRPPLKKYSFGAL-SQPGPHSVQPLLKHIKKKAKMREQERQASGGGEMFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATKIKNYYKRKPGKDPGAPDCKYGETVYCHTSPFLGSLHPGQLLQAFENNLFRAPIYLHKMPETDFLIIRTRQGYYIRELVDIFVVGQQCPLFEVPGPNSKRANTHIRDFLQVFIYRLFWKSKDRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAMVSPEQCCAYYSMIAAEQRLKDAGYGEKSFFAPEEENEEDFQMKIDDEVRTAPWNTTRAFIAAMKGKCLLEVTGVADPTG-CGEGFSYVKIPNKPTQQKDDKEPQPVKKTVTGTDADLRRLSLKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQARSGEGPMSKFARGSRFSVAEHQERYKEECQRIFDLQNKVLSSTEVLSTDTDSSSAE-----DSDFEEMGKNIENMLQNKKTSSQLSREREEQERKELQRMLLAAGS-------ASAGNNHRDDDTASVTSLNSSATGRCLKIYRTFRDEEGKEYVRCETVRKPAVIDAYVRIRTTKDEEFIRKFALFDEQHREEMRKERRRIQEQLRRLKRNQEKEK---LKGPPEKKPKKMKERPDLKLKCGACGAIGHMRTNKFCPLYY-QTNAPPSNPVAMTEEQEEELEKTVIHN-DNEELIKVEGTKIVLGKQLIESADEVRRKSLVLKFPKQ---QLPPKKKRRVGTTVHCDYL-NRPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVSPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGSESQYTKTAQEIVNVCYQTLTEYDEHLTQLEKDI 1613          

Query:  149 PLAAMLPEKFKEM--DVRELFPEFRANKVLRFSRLFGIKASHRPRIWKGVKKRRKKKDIDNI------EEQGSKIKKLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAGDDSNGKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDV-PDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFS-QTSKTAIPGIKLQTMQQKRPINGDDTWYSIFPVENEELVYGRWEDEVIWDDGRMPR-LHPKIVSLDPNDDNIILGIPEDIDPSTLPSDEPIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQESLKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKPV-NKEEQEQQP-KRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFSIGNKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEKLGLKGNKKLSSKALAKAKKDLKLVCGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQHADKLRRETVKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKI 1615
            PLA ++     ++   V ELFPEFR  KVLRF RLFG    + P +W+  +++RKKK  + I      EE+ S   ++     W ++YA  P  P+    D  I    P     +   G+ D   K   ++  P+  +WR GPA  WYD+L +P     F Y                     + ++TE  S  K  +  +  + EE S +D+  D+ F MVTQ++WE+D++W+G+D+KHK  +    + + AGW+PS+  R A +++ Q   TA              ++ D  WYSIFP++NE+LVYGRWED +IWD   MPR L P +++LDPND+N+IL IP++ + +T  S+ P ++ K  +  +K+SR+LL ++G   VI+EE      + +  DP+N+SND YY PK Q+ L+ + G  ++QH+ P VEL+ PF PTH+GPIKLR FHRPP+K++S G L      + V PL KHIKKKAK RE ER+ +GGGE+FFMRTP+D++GKDG+L+L E+ EE+ PL+  VGM +KIKNYYKRKP  D G    KYGE+   HTSPFLG++ PGQ +QA ENN+FR+P++ H  P SDF+IIRTR  + IRE+  +FVVGQ+CPL+EVPGPNSKRAN   RDFLQVFIYRLFWKS+D P+RI+M++IKKAFP+HSESSIRKRLK CA+F RTG DSNWWV+K++FRLPTEEEIR+MV PE CCAY+SMIAAEQRL+DAGYGEK  FA ++E++ED  +K+DDE++ APWNTTRA+I AMKGKCLL++TG ADPTG  GEGFSYV+IPNKP   K+++E QP K+TVTGTDADLR+L LK+A+ +LR  GVPE+EI  LSRW+VIDVVRT+STE+ ++GE    KF+RG+RFS+AEHQERY+++CQR+F +QN+VL S+EVLS+D   SS E     D DF EMGKN+ENML NKKTSSQ  REREE ER+ LQ+M++           +  G+  + D+    +S N S   + LKI RTF+ E+GKE+ R E VRK  VI+ Y+++R TKDE+FIR+FA  D+Q +EEM+KERRRIQEQLRR+KRN+EKEK               K + DLKL CGACG  GHMRTNK CP +  +        VAMTE+ EE+LEK ++ N + EEL+ V+GTK+ L  ++++ AD++RR+++ LK PKQ   Q   KK+ R GT  HCDYL N  ++   RRRTDP++T ++ LE I N +R +     F  PVN K +  Y+ +I  PMDLQT+REN++K+ Y  REEF   +  IV NSA +NGP+   TQ ++ ++DL   KL E EDKL +LEKAINPLLDD+DQVA ++ILDNI+ +K+ ++ +SWPF  PVNKK    YY+++ +PMDLETI   ++K++Y SR  FL D+ LI +NS++YNG  S +T    +I++V   TL EY +HLT LE+ I
Sbjct:  231 PLAGIMQHDATKLLPSVTELFPEFRPGKVLRFLRLFG-PGKNVPSVWRSARRKRKKKHRELIQEGQVQEEECSVELEVNQKSLWNYDYAP-PPLPDQCLSDDEITMMAPVESKFSQSTGDTD---KVMDTK--PRVAEWRYGPARLWYDMLGVPEDGSGFDY-------------------GFKMKKTEHESTIKCNIMKKLRKLEENSGVDLLADENFLMVTQLHWEDDIIWDGEDVKHKGTKP--QRASLAGWLPSSMTRNAMAYNVQQGFTAT-------------LDDDKPWYSIFPIDNEDLVYGRWEDNIIWDAQNMPRILEPPVLTLDPNDENLILEIPDEKEEAT--SNSPSKENKK-ESSLKKSRILLGKTG---VIKEEPQQNMSQPEVKDPWNLSNDEYYYPK-QQGLRGTFGGNIIQHSIPAVELRQPFFPTHMGPIKLRQFHRPPLKKYSFGAL-SQPGPHSVQPLLKHIKKKAKMREQERQASGGGEMFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATKIKNYYKRKPGKDPGAPDCKYGETVYCHTSPFLGSLHPGQLLQAFENNLFRAPIYLHKMPESDFLIIRTRQGYFIRELVDIFVVGQQCPLFEVPGPNSKRANTHIRDFLQVFIYRLFWKSKDRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAMVSPEQCCAYYSMIAAEQRLKDAGYGEKSFFAPEEENEEDFQMKIDDEVRTAPWNTTRAFIAAMKGKCLLEVTGVADPTG-CGEGFSYVKIPNKPTQQKDDKEPQPVKKTVTGTDADLRRLSLKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQARSGEGPMSKFARGSRFSVAEHQERYKEECQRIFDLQNKVLSSTEVLSTDTDSSSAE-----DSDFEEMGKNIENMLQNKKTSSQLSREREEQERKELQRMLL-------AAGSAAAGNNHRDDDTASVTSLNSSATGRCLKIYRTFRDEEGKEYVRCETVRKATVIDAYVRIRTTKDEEFIRKFALFDEQHREEMRKERRRIQEQLRRLKRNQEKEK---LKGPPEKKPKKMKERPDLKLKCGACGAIGHMRTNKFCPLYY-QTNAPPSNPVAMTEEQEEELEKTVIHN-DNEELIKVEGTKIVLGKQLIESADEVRRKSLVLKFPKQ---QLPPKKKRRVGTTVHCDYL-NRPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVSPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCHQTLTEYDEHLTQLEKDI 1639          

Query:  149 PLAAMLPEKFKEM--DVRELFPEFRANKVLRFSRLFGIKASHRPRIWKGVKKRRKKKDIDNIEEQGSKIK-----KLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAGDDSNGKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSKTAIPGIKLQTMQQKRPINGDDTWYSIFPVENEELVYGRWEDEVIWDDGRMPRL-HPKIVSLDPNDDNIILGIPEDIDPSTLPSDEPIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQESLKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKPVNK--EEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFSIGNKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEKLGLKGNKKLSSKALAKAKKDLKLVCGACGGKGHMRTNKTCPKF----VPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQHADKLRRETVKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKI 1615
            PLA ++     ++   V ELFPEFR  KVLRF  LFG    + P +W+  +++RKK      EEQ  +++     ++     W ++YA  P  PE    D  I    P     +   G+ D   K T ++  P+  +WR GPA  WYD+L +      F Y        + +   +  +K +  EE  +             EE  G+ L + D+ F MVTQ++WE+ ++W+G+DIKHK  +   +  + AGW+PS   R   +++     A              ++ D  WYSIFP++NE+LVYGRWED +IWD   MPRL  P +++LDPND+N+IL IP++ + +T  S+ P ++ K  +  +K+SR+LL ++G   VI EE      + +  DP+N+SND YY PK Q+ L+ + G  ++QH+ P +EL  PF PTH+GPIK+R FHRPP+K++S G L      + V PL KHIKKKAK RE ER+ +GGGE+FFMRTP+D++GKDG+L+L E+ EE+ PL+  VGM +KIKNYYKRKP  D G    KYGE+   HTSPFLG++ PGQ +QALENN+FR+PV+ H  P +DF+IIRTR  + IRE+  +FVVGQ+CPL+EVPGPNS+RAN   RDFLQVFIYRLFWKS+D P+RI+M++IKKAFP+HSESSIRKRLK CA+F RTG DSNWWV+K++FRLPTEEEIR+ V PE CCAY+SMIAA+QRL+DAGYGEK  FA ++E++ED  +K+DDE+  APWNTTRA+I AMKGKCLL++TG ADPTG  GEGFSYV+IPNKP  +  +++ Q  K+TVTGTDADLR+L LK+A+ +LR  GVPE+EI  LSRW+VIDVVRT+STE+  +GE    KF+RG+RFS+AEHQERY+++CQR+F +QN+VL S+EVLS+D    S E     D DF EMGKN+ENML NKKTSSQ  RE EE ER+ L++M++  GS       +  G+  + D     +S   S     LKI RTF+ E+GKE+ R E VRKP VI+ Y+++R TKDE+FI++FA  D++ +EEM+KERRRIQEQLRR+KRN+EKEK               K + DLKL CGACG  GHMRTNK CP +    VP  +      VAMTE+ EE+LEK ++ N + EEL+ V+GTK+    +++++  ++RR+++ LK PKQ   Q   KK+ R GT  HCDYL N  ++   RRRTDP++T ++ LE I N +R +     F  PVN K +  Y+ +I  PMDLQT+REN++K  Y  REEF   +  IV NSA +NGP+   TQ ++ ++DL   KL E EDKL +LEKAINPLLDD+DQVA ++ILDNI+ +K+ ++ +SWPF  PVNKK    YY+++ NP+DLETI   ++K++Y SR  FL D+ LI +NS++YNG  S +T    +I+++   T+ EY +HLT LE+ I
Sbjct:  230 PLAGIMQHDATKLLPSVTELFPEFRPGKVLRFLHLFG-PGKNVPSVWRSARRKRKKHRELIQEEQIQEVECSVESEVSQKSLWNYDYAP-PPPPEQCLADDEITMMVPVESKFSQSTGDVD---KVTDTK--PRVAEWRYGPARLWYDMLGVSEDGSGFDY-----GFKLRKTQHEPVIKSRMMEEFRK------------LEESNGTDL-LADENFLMVTQLHWEDSIIWDGEDIKHKGTKPQGA--SLAGWLPSIKTRNVMAYNVQQGFA------------PTLDDDKPWYSIFPIDNEDLVYGRWEDNIIWDAQAMPRLLEPPVLALDPNDENLILEIPDEKEEAT--SNSPSKESKK-ESSLKKSRILLGKTG---VIREEPQQNMSQPEVKDPWNLSNDEYYFPK-QQGLRGTFGGNIIQHSIPAMELWQPFFPTHMGPIKIRQFHRPPLKKYSFGAL-SQPGPHSVQPLLKHIKKKAKMREQERQASGGGELFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATKIKNYYKRKPGKDPGAPDCKYGETVYCHTSPFLGSLHPGQLLQALENNLFRAPVYLHKMPETDFLIIRTRQGYYIRELVDIFVVGQQCPLFEVPGPNSRRANMHIRDFLQVFIYRLFWKSKDRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAKVSPEQCCAYYSMIAAKQRLKDAGYGEKSFFAPEEENEEDFQMKIDDEVHAAPWNTTRAFIAAMKGKCLLEVTGVADPTG-CGEGFSYVKIPNKPTQQKDDKEPQAVKKTVTGTDADLRRLSLKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQAHSGEGPMSKFARGSRFSVAEHQERYKEECQRIFDLQNKVLSSTEVLSTDTDSISAE-----DSDFEEMGKNIENMLQNKKTSSQLSREWEEQERKELRRMLLVAGS-------AASGNNHRDDVTASMTSLKSSATGHCLKIYRTFRDEEGKEYVRCETVRKPAVIDAYVRIRTTKDEKFIQKFALFDEKHREEMRKERRRIQEQLRRLKRNQEKEK---LKGPPEKKPKKMKERPDLKLKCGACGAIGHMRTNKFCPLYYQTNVPPSK-----PVAMTEEQEEELEKTVIHN-DNEELIKVEGTKIVFGKQLIENVHEVRRKSLVLKFPKQ---QLPPKKKRRVGTTVHCDYL-NIPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNICYQTITEYDEHLTQLEKDI 1637          

Query:   74 YGDIEEALSDEDSSSSEGGSEN-ENEAEEEKGPAFGEEEGVDKETSAERTLDKILLDRSLMPPPSMDKTRGDKSRRPLAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFG--IKASHRPRIW---KGVKKRRKKKDIDN--IEEQGSKIKKLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAGDDSNGKEGNKDGNGKETSSRKGPKST---DWRTGPAEYWYDLLXLP----PVIDNFXYVSAANAASIEQDD-----TKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSKTAIPGIKLQTMQQKRPIN--GDDTW------YSIFPVENEELVYGRWEDEVIWDDGRMPR-LHPKIVSLDPNDDNIILGIPEDI----DPSTLPSDEPIRKVKIIQKHVKQSRMLLNRSGIISVIEEESP--PPPPKIDDMDPFNISNDVYYQPKTQESLKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQ---KHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKPVNKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGD-------HKFSRGN-RFSIAEHQERYRDDCQRLFVVQNRVLGSSEVL----SSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGS----------KGGSKSKKDEHDESSSNNFSIGNKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEKLGLKGNKKLSSKALAKAKKDL-KLVCGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEEL-----VNVDGTKVKLSAKVLQ-HADKLRRETVKLKIPKQA 1342
            Y +   A ++  SS+S GGS++ + E + EK   F E  G           D + L+   M P +    R D    PL+++L      +D R  F +F  NK LRFSRLF   IK + R  IW   +   K ++KK+ +    ++     KKLK++   +       +D E        +  RP   D+            E  ++K  + T    WRTGPA+ WYD++ LP     V   F    +    SI         T D++          ++   D V       E  ++ D+          + WE DV+ +G+++K ++L++  S     GW+P+ + RT   F   +       +     +  PIN  G D+       +SIFP    +L    WE  +IWD   MP  L P    +D  DD +I G+PED      P         RK     ++ K+S+M+L +       EE+        +  D DPFN+SND YY PK   S  +S    L+QH+TP   +   F PTH    +LR +HR P  R     ++ +       P+Q   KH ++ A  RE+ R+  GGGE+F+MR  +D+SGKD  LV+ E+ EEH  +L   GM SK+KNY+KR+  ND  P  F +GE   +H  PFLG + PGQS+Q++EN ++R+P++ H    +DF++IR+  ++ IR +  +FV GQ+CPLYEVP PNSKRA  F RDFL  FIYRLFW S  +P+R+KMD+++ AFP ++ES+IRKRLK C+ F R G ++ +W +K +FRLP++EE+ SMV PE CCA +SM+AAEQRL+DAGYGEK+ F  ++++  +  + ++DE+K APWNTTRA++ + + KCLL  TG ADPTG  G+GFSYVR+  KP   E     PK+ VTGT+ADLRKLPLK+A+ I R  GV E+EI  L+RW++IDV+RTLST+  KA +DG+        +F+RGN RFS A+ QE+YR  CQR+F  QN+ L +++ +     S +A+S  EE     E   E  K  +N+  ++K    F  E EE ER  L++MI G  ++  +              K  S+  +D    +S  +    N+ LKI RT K  DGK+ TR E+V +P +IE Y ++R T+D+ FI+ +A +D+Q KEE +K++RR+Q+Q+RR+K+NEEK    ++   +   K +     +L K+ C AC   GHM+TN+ CP +         G   +T   EED    +M ++    L     V VDGTKVK +    +   ++ R E +K K+ K A
Sbjct:   33 YKNHPAARNEACSSASNGGSKSVKMEPKVEKNEEFEEYIG-----------DPVRLED--MEPFARPSLRDDA---PLSSILHPDLDGIDPRIFFKDFNPNKTLRFSRLFAQNIKHTSRAEIWWASRTFSKHQRKKEPEEPLADDVIVGAKKLKLNIIEKVPRVMLADDEEE-------RMRRPILTDA------------EEMAKKNEEGTVVQPWRTGPAKIWYDMMNLPMTSQAVNYGFKLKKSPQKVSIRSGKPLNYRTPDDLPSTSSGPAPNSAPFLDKVEVIDKSCEASTSEDI----LLPYQVIEWENDVILDGEEVKDQLLEEF-SNGRGCGWIPTQYTRTYEHFVYAANNN--AFEQMFDGKSAPINLTGPDSAILPTPGHSIFPSAPCDLDILPWETNIIWDADAMPSTLEPIDFLVDFQDDPLIYGMPEDRRHDEGPDHHHHHHHHRKDG---QYTKKSKMILGQVQQRQKQEEDEQMESTMAQFTDNDPFNLSNDDYYVPKAT-SKTLSNNSLLIQHSTPATNIATHFFPTHPSAFRLRYWHRTPFTR----RIVRHWQPMRFQPIQTPVKHQQRVAAMREAMRQAQGGGEVFYMRDVQDLSGKDETLVMIEYSEEHPVILSQPGMASKMKNYFKRRQANDSEP-TFTFGELAFSHQIPFLGQLQPGQSLQSIENMLYRAPIYLHKRQNTDFLLIRSMNQWYIRPLPSIFVAGQQCPLYEVPSPNSKRATVFVRDFLFAFIYRLFWASDSSPRRLKMDDVRNAFPHYAESNIRKRLKMCSTFVRQGSET-YWSLKPDFRLPSKEEVLSMVTPEMCCAQYSMMAAEQRLKDAGYGEKYFFTPENDEGSEDEVTIEDEIKCAPWNTTRAFLASQREKCLLDQTGIADPTG-CGQGFSYVRVSQKPHKDENATPVPKKLVTGTNADLRKLPLKEAKQICRGYGVKEEEISALTRWEIIDVIRTLSTQAAKATKDGEIIAVSGMARFARGNTRFSSADMQEKYRKHCQRIFDQQNQTLANTDPISTDDDSTDADSDNEELASRLESMLEANKGKKNISMSEKAKIDF--ETEEKEREDLKRMIHGTTNQVEKGEKKEEGEVTAEEKKSASQFGEDVAMSASKISGITANQQLKIYRTCKGPDGKDVTRIEIVTRPQLIEAYTRIRMTRDDTFIQVYAQMDEQYKEEKRKKKRRLQDQIRRMKKNEEKAAHKVQKMTEKKVKPIKPPNPNLQKMRCSACHAYGHMKTNRNCPLY---------GKDPLTPLKEEDEGSTIMTSVSSASLVAPDAVQVDGTKVKFNLNFAEIRKEQNREEKLKRKLAKMA 1304          

Query: 1351 RSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKI 1615
            + R+  +   DYL     + A R R DP +  ++ L  I N+L+++  +  F+ PVN K++  Y+++IKNP+ LQ I++ I ++ Y  R++FL D+  +  NS ++NG  +I T  A++++ L   ++ E E K + LEK INPLLD ND +  +Y+L  I+ +K+K++ +S  F   V+ K+  AYY  + +PMDL  +  K    +Y S  EFL D E IY+NS+ +NG  S ++ K  ++ ++    +++  D L  LE  I
Sbjct: 1383 KRRSSMMPEEDYLQGP-LKVAHRARADPKVVMSSMLTDIVNELKMISGSDAFVTPVNSKKVVDYYNIIKNPISLQEIKKKISEQSYLLRKDFLDDIKLMFDNSRMYNGDNNILTLTAQQMLQLAGKRMIEREQKFIGLEKQINPLLDTNDLIGFSYLLGEIV-QKMKNIPKSALFHTRVDPKKIPAYYLKISDPMDLSIMEQKSKSQEYKSIDEFLKDAEKIYTNSVVFNGAESVYSLKAKEMFEMAEMLVKDQMDTLGELERNI 1645          

Query:  536 DMDPFNISNDVYYQPKTQESLKVSTGRT--LLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGP--LMDYTAFYGVIPLQKHIKKKAKARESERELAGG----GEI----------------FFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPG--KFKYGESTIAHT---SPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTR--TEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGE--------KFLFAQQDEDDEDTALK-MDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKPVNKEEQEQQ---PKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDH--KFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLG 1054
            ++D FN+SND +Y+P  +   +   G T  ++QH+ P ++L    V TH+    L   HRP +   S  P  ++ Y     +               S   + GG    G I                       D+S +DG LVL E+ E+H PL+  VGM  +I+NYYK+K  +D GP    F+ GE  +      SPFLG ++PGQ++Q++ NN+F+ P+ +H    +DF+++++R    + IR+V  ++  GQ  P  EVP PNS+ AN F +  LQ +IYR F K  +  +R+K+ +I  AFP+ SE+SIRKRLK CA+F R G DS WW +K+NF LPTEEE + +V PEA  ++ SM+   QRL+D G             L    DED    ++K ++DEL + PWN T +++ AM+GK  LQ+    DPTG   E +SY+++P K VN++++  +    K  VTGTDADLRKL L  ++ +L   GV E+ I  L+RWQ ID+VR  S+E   A        KF+RG+R+S+     +Y++ CQ +F  Q + + 
Sbjct:  835 EIDKFNLSNDKFYRPVRKPPPRPPNGSTKVVIQHSLPGIKLS--LVKTHLTKEDLIYAHRPRILFPSNVPFRIIIYNKEGSLSGDLSSSSNNLLLNSSTNSIMGGHNMRGSINGGMMSSSSSSSSSSSKKSLHKSDLSARDGRLVLIEYTEQHPPLVSNVGMGLRIRNYYKKKNTHDTGPKDLNFEDGELVMLDNNEESPFLGDINPGQTIQSVVNNLFKVPIHKHNSANTDFLLVKSRDGKRWYIRDVGPIYAAGQILPEVEVPAPNSRNANMFLKSRLQAYIYRQFLKKSNPQRRLKITDICSAFPSQSETSIRKRLKDCADFQRGGDDSGWWTVKDNFTLPTEEEFQKLVTPEAVVSFESMLIGLQRLQDNGIIHFTAPGTIPTILGNLDDEDPIKKSIKPVEDELSITPWNLTGSFLSAMQGKGRLQIIS-DDPTGREDE-YSYLKMPQKVVNQKQKAIKLALQKNQVTGTDADLRKLSLSASKTVLLELGVDEETINKLARWQRIDLVRKKSSEAALASNSNAAMTKFARGSRYSLDHQNLQYKEQCQLVFDNQIKAIA 1394          

Query: 1380 ITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQN-AKKLMDLVIAKLSENEDKLMKLEKAI 1492
            +  +   E I ++LR  DE + F   V PK  P Y  VIKNP+DL T+R+  +  +Y  + +F+  +  +VAN   +N     H    A+KL+   +  L+  + ++  LEK+I
Sbjct: 2115 VELSNIFERILDKLRTNDEFIAFRHKVTPKLAPDYHKVIKNPIDLTTMRDRNRHWEYKSKNQFIDAIKLMVANCFEYNEKRFSHLLPIAEKLLTSTLQLLAPFDSQIGDLEKSI 2228          

Query:  642 MRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTI--------AHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRT-RTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPK---RIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGE-----KFLFAQQDEDDED----TALKMDDELKVAPWNTTRAYILAMKGKC----LLQLTGPADPTGPAGEGFSYVRI-PNKPV----NKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDH----KFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENML 1089
             R   D+S KDG + L E+ EE   LL   GM +++  YY++   +D+     +     +        A  SPFLG +  G     LE NM+R+PVF H    +D++++R+ +   S+R +D L+ VGQ+ P  EV  P +K   N+  + + V++YR F ++R+ P    +I+ DE+    P  +E+ +RKRLK CA+  +      +++ + +FR+P+EEE+R ++ PE  C Y SM A + RL+  G  +         A     DE      A  ++ EL++  WN T  ++            L++TG  DP+G  G GFSYVR+ P  PV    +K++       TVTGTDADLR+L +  AR +L   GVPE++I  L+RW  I +VR LS+E+  +G   D     KF+RG R S  + Q++ ++ CQ ++   +R + S   +  +E  S  E     + D +    +LEN+L
Sbjct:  732 FRKKSDLSVKDGHVFLMEYCEERPLLLANAGMAARLCTYYQKTSPSDQTATSLRSNSDGLGTMLAIDPADKSPFLGNIRSGSHQSCLETNMYRAPVFPHKVATTDYLLVRSPKGMLSLRRIDKLYAVGQQEPHMEVFSPGTKNMQNYILNRILVYVYREF-RAREKPGIIPQIRADELPIQ-PPITEAIVRKRLKHCADLRKGPKGHLFYIQRPDFRIPSEEELRRLLTPENVCCYESMQAGQYRLKHLGIEKLTQPVGLASAMNQLPDEAIELAAAAHIERELQITSWNLTSNFVACTNQDKENIERLEITGVGDPSG-RGLGFSYVRVTPKAPVSNSTHKKKSAAAKGTTVTGTDADLRRLSMDAARELLLKFGVPEEQIDKLTRWHRIAMVRKLSSEQAASGVTMDEIPVSKFARGQRMSFLQLQQQTKEKCQEIW---DRQIQSLSAMDGNENGSDTEA----NSDLDSFAGDLENLL 1203          

Query: 1366 TNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQN-AKKLMDLVIAKLSENEDKLMKLEKAI 1492
            T Y P  +R     +  +  LE I + LR M  +  F +PV  K  P YFD+I+ PMDL TIR+ ++K +Y  RE+F  DV QI  N+  +N     H    A +L++L    L E+ D L   E AI
Sbjct: 1681 TEYTPPAKRHRGGEVELSNILEKIVDHLRTMSCSFLFRKPVTKKEAPDYFDIIERPMDLGTIRDKVRKMEYKNREDFRHDVAQIALNAHTYNLNRHPHIPPLADELLELCDYLLEESADVLDDAEYAI 1808          

Query: 1501 QVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYN-GENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKE 1617
            +V L+ IL+ I++  +++M  S+ F KPV KK+   Y++I++ PMDL TI  KV K +Y +R +F  D+  I  N+  YN   +        ++L++    LEE +D L + E  I++
Sbjct: 1694 EVELSNILEKIVDH-LRTMSCSFLFRKPVTKKEAPDYFDIIERPMDLGTIRDKVRKMEYKNREDFRHDVAQIALNAHTYNLNRHPHIPPLADELLELCDYLLEESADVLDDAEYAIED 1810          

Query:  540 FNISNDVYYQ---PKTQESLKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKAR-ESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHT---SPF--LGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFS----IREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVR 945
            FNISND  Y+      Q  ++ +  +  ++HA    +L  P+  T +    +R +HRP          M +     ++     ++K++K + +SEREL          T E   G     +L EF EEH  +L   GM S+I NYY++K E D+   K + GES +      SPF   G++ PG+    L N M R+P+F+H  P +DF++IR  + +     ++ ++ +FV GQ  P+ +VPGP+S++    +++ L++ ++RL  +S +    I+  ++ K F   +E  IR+RLK   E+ + G    +W +K+N  +P E   RSMV PE  C   SM    ++L DAGYG+       DED+E  A ++     +APW TTR +I A +GK +L L G  DPTG  GEG+S++R
Sbjct:  361 FNISNDPAYEMLKQNHQSKVRNTLSQLAIEHAAFAEKLTFPYYKTRLSKRAVRSYHRP---------TMSFKPNAAIVFSPLIVRKRSKDKHKSEREL-------IPTTKEITMGDTTHAILVEFSEEHPAVLSNAGMASRIVNYYRKKNEQDESRPKLEVGESHVLDVQDRSPFWNFGSVEPGEITPTLYNKMIRAPLFKHEVPPTDFILIRNSSSYGSKYYLKNINHMFVSGQTFPVTDVPGPHSRKVTTASKNRLKMLVFRLIRRSPNGGLFIR--QLSKHFSDQNEMQIRQRLKEFMEYKKKGDGPGYWKLKSNEVVPDEAGTRSMVSPETVCLLESMQVGVRQLEDAGYGKTMDEINDDEDEEQPAEQL-----LAPWITTRNFINATQGKAMLTLFGEGDPTG-IGEGYSFIR 755          

Query: 1150 NKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQL--------RRIKRNEEKEKLGLKGNKKLSSKALAKAKKDLKLVCGACGGKGHMRTNKTCPKF 1273
            +K+L+IVR ++ ++G    + E +  P+VI  Y+K R   DEQ     A +    +   ++ RRR++++L        RR  R+  KE + L G          + +K     C  CG  GHM+TNK CP F
Sbjct:  844 DKVLRIVRLYRDKNGNLERKQETIHDPIVIHAYLKKRREIDEQSTALDAVVPTGDEAIDRRNRRRLEQELAKSQKNWERRRARHAAKEGINLNG----------EGRKPTTRKCSNCGQVGHMKTNKICPLF 965          

Query:  540 FNISNDVYYQ--PKTQESLKVSTGRTL-LQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHT---SPF--LGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTR-----TEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNK 949
            FN+SND  YQ   KT ++   ST   L +QH+ P + LQ+PF    +   +LR FHR                   + P  K +  K KAR+ +R+     +  F  + +   G    + L E+ E+    L   GM +K+ NYY++  E D    K   GE+ +      SPF   G + PG  V  L NNM R+PVF+H    +DF++ ++        F +R ++ LF VGQ  P+ E+PGPNS++  +     L++ IYR+   + ++ K I +D I K FP       R+++K   ++ R G +   W +K++ +L   E ++S++ PE      SM    Q   D    E + F        D+ LK  +E  + PWN T+ +I + + + ++Q+ G  DPTG  GEGFS+++   K
Sbjct:  439 FNLSNDDKYQILKKTHQTKVRSTISNLNIQHSQPAINLQSPFYKVAVPRYQLRHFHRENFGSH-------------IRPGTKIVFSKLKARKRKRDKGKDVKESFSTSQDLTIGDTAPVYLMEYSEQTPVALSKFGMANKLINYYRKANEQDTLRPKLPVGETHVLGVQDKSPFWNFGFVEPGHIVPTLYNNMIRAPVFKHDISGTDFLLTKSSGFGISNRFYLRNINHLFTVGQTFPVEEIPGPNSRKVTSMKATRLKMIIYRIL--NHNHSKAISIDPIAKHFPDQDYGQNRQKVKEFMKYQRDGPEKGLWRLKDDEKLLDNEAVKSLITPEQISQVESMSQGLQFQED---NEAYNF--------DSKLKSLEE-NLLPWNITKNFINSTQMRAMIQIHGVGDPTG-CGEGFSFLKTSMK 833          

Query: 1151 KILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQ---KEEMKKERRRIQEQL--------RRIKRNEEKEKLGLKGNKK-----------LSSKALAKAKKDLKLVCGACGGKGHMRTNKTCPKF 1273
            KILKIVR  + E+G    +T  +R P VI+ YIK++E +D++ + +    D  +    EE++K+++ +Q +L        RR  R   K   G    +               KA     K+    C  CG  GH+RTNK+CP +
Sbjct:  913 KILKIVRKKRDENGIIQRQTIFIRDPRVIQGYIKIKE-QDKEDVNKLLEEDTSKINNLEELEKQKKLLQLELANLEKSQQRRAARQNSKRNGGATRTENSVDNGSDLAGVTDGKAARNKGKNTTRRCATCGQIGHIRTNKSCPMY 1056          

Query:    3 NLTGFMFGNVDSSGNLDGDSVLGGLCGTSDVMRGLSSL--LSTKELLKDVLSVKEEEGDLCEGEVVKAE-DATDYGDIEEALSDEDSSSSEGGSENENEAEEEKGPAFGEEEGVDKETSAERTLDKIL-----------LDRSLMPPPSMDKTR-----------GDKSR--RPLAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFGI-KASHRPRIWKGVKKRRKK---KDIDNIEEQGSKIKKLKMSH-AWEFNYADFPEDPEAYEVDAAIKFHRP---AGDDSNGKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSKTAI---------------PGIKL--QTMQQKRP-INGDDTWYSIFPVENEELVYGRWEDEVIWDDGRMPRL-HPKIVSLDPNDDNIILGIPEDIDPSTLPSDE--PIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQES---LKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKPV-NKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFSIGNKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEKLGL---------KGNKKLS------------------------SKALAKAKKDLKLVCGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQHADKLRRETVKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQTDIDSLGAA---LGVEEPPKKKRGRPRKKG----PKIVSAEFIDV-----GSEEAPGGSMEARHSEEAEGSGLLEEDLQYSSEEDWEEVVE---EDNSSSFTVTVD-PL-----DQQTPHAEDQVDPLVTMNFYXDNQATAGG----EEELEVDENYDPSAFLHNLGKQLPTEIKEE---DEYIPPPVAAQSAEDENDFGNSTYKEEPVDIKDDLDISDSDDNDEDAIEGSPVNKQ 1833
            +LTGF+FGN++  G L+ D +       ++  + LS+L  L     LK+++ V     D  + +   +E   + +GD      +++S+S+E    NE+   E K P+  +   +++    E    K             +D  LMPPP +  T+           GDK +   PLAAMLP K+  ++V +LFP+FR  KVLRFSRLFG  K S  P IWK V+K+RK+   KD  N  +  S  +  K  H  W  +YA+ P  PE  + D   KF +P   A  DS  +  +KD  G        PK  DWR GPA+ WYD+L +P   + F Y                  K K ++  E         T E +E  EG   + PDDAF MVTQ++WE+DVVW+G+DIKHKVLQKLNSKTNAAGWVPS+ NRTA +FSQ  K  +               PG+K   Q + + RP    DDTWYSIFPVENE+LVYGRWED+VIWD   M  +  P I++LDPND+NIILGIP+DIDPS   + +  P+ KVKI   HVK+S++LL ++G+I+V++E++PPPPPK  + DPFNISNDVYY P++ E+   LKV  G  L+QH+TPVVEL+APF+ TH+G ++LR FHRPP+KRFS GPL  +   + V+PL KHIKKKAK RE+ER  +GGG++FFMRTPED++G+DG+++L EF EEH PL++ VGMCSKIKNYYKRK   D GP  +KYGE+  AHTSPFLG + PGQS+QA+ENNM+R+P++EH  P SDF++IRTR ++ IRE+D L+V GQ+CPLYEVPGPNSKRANNF RDFLQVFIYRLFWKSRDNP+RIKM++IKKAFP+HSESSIRKRLK CA+F RTG DSNWWVIK  FRLPTEEEIR+MV PE CCAYFSM+AAEQRL+DAGYGEKF+F   ++DDE+  LKMDDE+KVAPWNTTRAYI AMKGKCLLQLTGPADPTG  GEGFSYVR+PNKP  NKEEQE QPKRTVTGTDADLR+L L +A+A+LR  GVPE+EI  LSRW+VIDVVRTLSTEK KAGE+G  KFSRGNRFSIAEHQERY+++CQR+F +QNRVL S+EVLS+DE ESS+E     DED  EMGKN+ENML+NKKTS+Q   EREE ER+ L+KMIM    +  +          ++         N++   +ILKIVRTF+  +GKEFTR E VRKP VI+ Y+K+R TKD+ FIRQFAT+D+ QKEEMK+E+RRIQEQLRRIKRN+EKE+L L          G +KL                         S+   K K DLKL CGACG  GHMRTNK CP +        + +VAMTE+ EE++EKQL  N ++E+LVN+DGTKVKLS+K+L+HA++++R+T+ LK+PK+A+    AK+R R  +  HCDYL   N R A RRRTDP++  +T LE I N++R M +   FL PVNPK++  Y+ +++ PMDLQTIREN+++KKY  REEFL+DVNQIV NS ++NG +   T  A+++++  + +L E E++LM+LEKAINPLLDDNDQVALT+ILDN++N K+K+M ESWPF+KPVNKK  K YY I+K PMDLETIS KV  ++YHSRHEFL DIE I  N + YNG +S FT K  +++ + +ATL+EY +HLT LE KI   Q  A++  D   +G       + EP +  +             I   +++DV      SE+        R  ++ + + +LEEDLQ+SSEE+ +EV     EDN     ++ + P+     D  +  A + +  L +M +Y  N+         EE ++VD NYDPS FL +    LP   +EE   DE +  P                 ++  + I DDL +S+S+D   + +  +PV ++
Sbjct:   17 DLTGFLFGNINEQGQLESDVL------DTESQKQLSNLGKLGLGSTLKEMIGVDSIPKDDSDSDYDNSEGQKSKFGD-----ENKESNSAES-QNNEDSNFESKSPSAVDFSDINELAEEEEEEAKPENYDADDEHPNEIDNKLMPPPPVPTTKENSESIVTTDDGDKKKLETPLAAMLPSKYANVNVTDLFPDFRHGKVLRFSRLFGPGKPSSLPNIWKNVRKKRKRRKHKDSANQHDSDSNSEDEKPKHRGWFIDYAE-PPPPEQIQSDDEEKFLKPMENATVDSKAETQSKDDTG--------PKVADWRFGPAQIWYDMLEVPETGEGFNY----------------GFKLKEDQPPEP--------TPEATEPREGD--EFPDDAFLMVTQLHWEDDVVWDGNDIKHKVLQKLNSKTNAAGWVPSSGNRTAQAFSQPGKGGLLSGSSVRLPIPAPPLPGMKAKAQILNKPRPDPEQDDTWYSIFPVENEDLVYGRWEDDVIWDADNMKNIPKPSILTLDPNDENIILGIPDDIDPSKQIAGQATPV-KVKIPHPHVKKSKILLGKAGVINVLQEDTPPPPPKSPNRDPFNISNDVYYMPRSSETTMRLKVGGG-NLIQHSTPVVELRAPFIQTHMGLMRLRNFHRPPMKRFSHGPLA-HPGPHPVMPLVKHIKKKAKQREAERMASGGGDVFFMRTPEDLTGRDGDIILIEFCEEHPPLMNQVGMCSKIKNYYKRKAAKDSGPPSYKYGETAYAHTSPFLGILHPGQSIQAIENNMYRAPIYEHDKPCSDFLVIRTRQQYYIREIDALYVAGQQCPLYEVPGPNSKRANNFVRDFLQVFIYRLFWKSRDNPRRIKMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVIKPEFRLPTEEEIRAMVSPEQCCAYFSMVAAEQRLKDAGYGEKFIFTPAEDDDEEMQLKMDDEVKVAPWNTTRAYIQAMKGKCLLQLTGPADPTG-CGEGFSYVRVPNKPTQNKEEQESQPKRTVTGTDADLRRLSLNNAKALLRKFGVPEEEIKKLSRWEVIDVVRTLSTEKAKAGEEGMDKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLSSAEVLSTDEGESSDE---GSDEDIEEMGKNIENMLANKKTSTQLSLEREEQERQELRKMIMEGDEKKGKDKKKDDDDNQEQ--------TNYAQQGRILKIVRTFRDAEGKEFTRVETVRKPAVIDAYVKIRSTKDDAFIRQFATLDEAQKEEMKREKRRIQEQLRRIKRNQEKERLALGLAASSNPAAGGEKLGSNDSPSSQSFNISPNKSTVISPPKSRRKTKLKPDLKLKCGACGNVGHMRTNKACPLYQNSGSNAPM-NVAMTEEQEEEIEKQL--NTDDEDLVNIDGTKVKLSSKLLKHAEEMKRKTLLLKVPKEAM---NAKRRRRGMSDLHCDYLKRHN-RTANRRRTDPVVVLSTILENILNEMRDMPDVQPFLFPVNPKKVMDYYRIVQRPMDLQTIRENLRQKKYQSREEFLADVNQIVENSTLYNGAKSSLTVAAQRMLNKCVERLGEKEERLMRLEKAINPLLDDNDQVALTFILDNVINTKLKAMSESWPFLKPVNKKLVKDYYSIIKRPMDLETISKKVAAHKYHSRHEFLVDIEQILENCILYNGRDSPFTEKAEQLVKICKATLDEYDEHLTQLENKISLAQERAMQDDDQAWMGGEEENYTIAEPDRISQASSPDHSLFMKSNIDDYDYVDVEGGIQTSEDVTASVSRPRKRKKKDEAAILEEDLQFSSEEELDEVPLNEFEDNKGGLVISAEMPMEGVNADDDSQQAAEAMVQLGSMGYYQQNEGDGTDLVYKEESMDVDPNYDPSDFLMS---GLPMHKQEEIKIDETVLQP-----------------QDSAMKIHDDLAVSESEDEGGNNVGEAPVQEE 1879          

Query:    3 NLTGFMFGNVDSSGNLDGDSVLGGLCG---TSDVMRGLSSLLSTKELLKDVLSVK--------EEEGDLCE----GEVVKAEDATDYGDIEEALSDEDSSSS-----EGGSENENEAEEEKGPAFGEEEGVDKETSAERTLDKILLDRSLMPPPSMDKTRGDKSRRPLAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFGI-KASHRPRIWKGVKKRRKK------KDIDNIEEQGSKIKKLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAGDDSN-GKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSKTA----IPGIKLQT----------------------MQQKRPINGDDTWYSIFPVENEELVYGRWEDEVIWDDGRMPRL-HPKIVSLDPNDDNIILGIPEDIDPSTLPSDE-PIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQES---LKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKP-VNKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNF-SIGNKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEK-LG--LKGNKKLSSKALAKAKKDLKLV--------------------------------------------CGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQHADKLRRETVKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQTDIDS--LGA---ALGVEEPPKKKRGRPRKKGP----KIVSAEFIDVGSEEAPGGSMEARHSEEAEGSGLLEEDLQYSSEEDWEEVV-----EEDNSSSFTVTVDPL-----------DQQTPHAEDQVDPLVTMNFYXDNQATAGGEEELEVDENYDPSAFLHNLGKQLPTEIKEEDEYIPPPVAAQSAEDENDFGNSTYKEEPVDIKDDLDISDSDDNDEDAIEGSPVNKQSTSHSNVPPPPPLEETPDDDTLWF 1857
            N+TGF+FGN+D +  L+ D +L         S    GLSS +    L +D+ + K        EEE D  +      V K+  A D+ DI E   DE          EG  E EN   +       +EE + K  +       I  ++  +     +  R  K   PLA+MLP K+  +DV ELFP+FRANKVLRFSRLFG  K S  P+IW+GVK+RRKK      +D D+  +Q  K  K K    W   Y    + P+ Y  D   K   P  D    GK G    NG       GPK  DWR GPA+ WYD+L +P   D F Y         +  D  DE+          N+K+K+I  +     EE S     DDAF MV+Q++WE+DV+WNGDDIKHKVLQKLNSK NAAGWVPS+ NRTA +FSQ  K A       ++L T                       QQ R  N DDTWYSIFPVENEELVYG WE+EVIWD   M ++  PKI++LDPND+NI+LGIP+DIDP+ +  D  P  KVKI   HVK+S++LL ++G+I+V+EE++PPPPPK  D DPFNISND YY P++ E+   LKV  G  L+QH+TPVVEL+ PFV TH+GP++LR FHRPP+++FS GP+  ++  + V+PL KHIKKKAK RE ER  +GGG++FFMRTPED++GKDGELVL EF EEH PL++ VGMCSK+KNYYKRK   D+GP K+KYGE+  AHTSPFLG ++PGQS+QA+ENNM+R+P++EH  P +DF++IRTR ++ IREVD LFV GQECPLYEVPGPNSKRANNF RDFLQVFIYRLFWKSRD P+RIKMD+IK+AFP+HSESSIRKRLK CA+F RTG DSNWWVIK +FRLPTEEEIR+MV PE CCAYFSMIAAEQRL+DAGYGEKFLF  QD+DDE+  LKMDDE+KVAPWNTTRAYI AMKGKCLLQL GPADPTG  GEGFSYVR+PNKP ++KEEQE QPKRTVTGTDADLR+L L +A+A+LR  GVPE+EI  LSRW+VIDVVRTLSTEK KAGE+G  KFSRGNRFSIAEHQERY+++CQR+F +QNRVL S+EVLS+DE ESSEE+         EMGKN+ENMLSNKKTS+Q   EREE +R  L+KM+MGE      +   K   + KKD+ ++S  NNF S   ++LKI RTF+  +GKE+TR ELVRK  VI+TYIK+R +KDE FI+QFAT+D+ QKEEMK+E+RRIQEQLRRIKRN+E+E+ LG  + GN   SS    ++  +                                                CGACG  GHMRTNK CP +        + +VAMTE+ EE++EKQL  N ++++LVNVDGTKVKLS+K+++HA++++R T+ LK+PK+AV    +KKR R    +HCDYL     RPA RRRTDP++  +T LE I N++R + +   FL PVN K +P Y+ +I+ PMDLQTIREN++ KKY  REEFL+DVNQIV NS ++NG +   T  AK++++  + +L E ED+LM+LEKAINPLLDDNDQVALT+ILDN++N K+KSM E+WPF+KPVNKK  K YY ++K PMDLETIS KV+ ++YH+RHEFL DIE I  N   YNG+ S FT K   ++ V + TL+EY +HLT LE  I  VQ+ A+EQ DIDS  LGA      + EP  +       + P     +   +F+DV  +    GS     S  ++   +LEEDLQ+SSE++++EV      + +N+   T+ ++ +           D  +  A + +  L  + FY  +Q     +E ++VD NYDPS FL                     +A   A DE              I+DDL +S+SDD+     E +P  KQ TS    P P P E+   D  LWF
Sbjct:   17 NMTGFLFGNIDDTVQLE-DDILDPEAKPHRASLNRLGLSSFIREMMLNEDITAEKINESNDKIEEENDTTDEKDINYVEKSPSALDFSDINELAEDEKEEKYKQDIFEGKPEKENADYDA-----DDEEVIIKSDTQLMPPPPIPEEKEALTAEEAEAARQRKLETPLASMLPSKYANVDVTELFPDFRANKVLRFSRLFGPGKPSSLPQIWRGVKRRRKKKRHHDVRDSDSGSDQEEKKSKFK---GWAMQYGT-DQTPDMYCSDDENKLLMPIEDKEQIGKTGETGENGD-----MGPKVADWRFGPAQLWYDMLQVPETGDGFNY-------GFKLIDKTDEL----------NNKDKNIRDTN----EEFS-----DDAFLMVSQLHWEDDVIWNGDDIKHKVLQKLNSKNNAAGWVPSSGNRTAQAFSQPGKGAPVSVTSNVRLATSQITTPLHMQSQKTKMNMNKANQQQNREENYDDTWYSIFPVENEELVYGLWEEEVIWDPENMKKIPKPKILTLDPNDENIVLGIPDDIDPALVHKDNGPQPKVKIPHPHVKKSKLLLGKAGVINVLEEDTPPPPPKSPDRDPFNISNDTYYMPRSSETTLRLKVGGG-NLIQHSTPVVELRVPFVQTHMGPMRLRNFHRPPLRKFSHGPVA-HSGPHSVLPLIKHIKKKAKQREQERIASGGGDVFFMRTPEDLTGKDGELVLIEFSEEHPPLMNQVGMCSKVKNYYKRKAGKDQGPQKYKYGETAYAHTSPFLGILTPGQSIQAVENNMYRAPIYEHKIPETDFLVIRTRQQYYIREVDALFVAGQECPLYEVPGPNSKRANNFVRDFLQVFIYRLFWKSRDTPRRIKMDDIKRAFPSHSESSIRKRLKLCADFKRTGMDSNWWVIKPDFRLPTEEEIRAMVSPEQCCAYFSMIAAEQRLKDAGYGEKFLFTPQDDDDEEMQLKMDDEVKVAPWNTTRAYIQAMKGKCLLQLAGPADPTG-CGEGFSYVRVPNKPTISKEEQEAQPKRTVTGTDADLRRLSLNNAKALLRKFGVPEEEIKKLSRWEVIDVVRTLSTEKAKAGEEGMTKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLSSNEVLSTDEGESSEEDSSDI----EEMGKNIENMLSNKKTSTQLSLEREEQQRHELRKMLMGEV-----QEQDKKTKEKKKDDEEDSPVNNFNSQQGRVLKIYRTFRNPEGKEYTRVELVRKSAVIDTYIKIRNSKDETFIKQFATLDEAQKEEMKREKRRIQEQLRRIKRNQERERMLGGPMTGNNASSSNIFDRSSNNTPTTTSSNSILPFCNSFQSTSPASKHPKPDISPSKRKKPKLKPDLKLKCGACGNVGHMRTNKACPLYQNSITTAPV-NVAMTEEQEEEIEKQL--NTDDQDLVNVDGTKVKLSSKLIKHAEEMKRRTLLLKVPKEAV---NSKKRRRATGDDHCDYLKRQQ-RPANRRRTDPVVVMSTMLESILNEMRDLPDVQPFLFPVNAKAVPDYYKIIQRPMDLQTIRENLRLKKYQSREEFLADVNQIVENSTLYNGIKSSLTVAAKRMLETCVERLGEKEDRLMRLEKAINPLLDDNDQVALTFILDNVVNNKLKSMTEAWPFLKPVNKKLVKDYYNVIKRPMDLETISKKVSAHKYHNRHEFLRDIEQILENCTVYNGKESPFTQKAELLVKVCKETLDEYDEHLTQLENNILLVQKRAMEQADIDSSWLGADEENYTIVEPEFRGSQTSSPENPFGKTNMEDFDFVDVEGDMEGDGS----RSVNSKKKDVLEEDLQFSSEDEFDEVPFGTDEQSENAEMETLELNEVRENTEGGVVLADDDSQQAAEAMVQLGNVGFYMTDQQLLQQDESMDVDPNYDPSDFL---------------------LAGLPARDEKSENK---------IQDDLAVSESDDD-----ENNPKQKQKTSQ---PLPQPEEDVGGD--LWF 1900          

Query:    3 NLTGFMFGNVDSSGNLDGDSV-------LGGLCGTSDVMRGLSSLLSTKELLKDVLSVKEEEGDLCEGEVVKAEDATDYGDIEEALSDEDSSSSEGGSENENEAEEEKGPAFGEEEGVDKETSAERTLDKILLDRSLMPPPSMDKTRGDKSRR---PLAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFGI-KASHRPRIWKGVKKRRKKKDIDNIEEQGSKIKKLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAGDDSNGKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTN-AAGWVPSTFNR------TAGSFSQTSKTAIPGIKLQTMQQKRPING----------------------DDTWYSIFPVENEELVYGRWEDEVIWDDGRMPRL-HPKIVSLDPNDDNIILGIPEDIDPSTLPS--DEPIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPK-TQESLKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKP-VNKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFS---IGNKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEKLGLKGNKKLSSKALAKAKKDLKLVCGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQHADKLRRETVKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLE 1602
            NLTGF+FGN+D  G L+ D +       LG L        GL S+L  + ++++  S  +++    E +  K+  A DY DI E                   AE+E GP                 LD  +L      P S   +  +  +R   PLAAMLP K+  +DVRELFP+FR +KVL FSRLFG  K S  P+IW+GVKK+RKKK   + E+   + +   +   ++F        PE    D   +F +P  D       N   N K +   KGP   DWR GPA+ WYD+L +P   + F Y                  K KR++    +   KD+                PD+AF M+TQ+NWE+DVVWNGDDIKHKV+QKLN+K   A+GW+P+  NR      T  +   T K A PG K           G                      DD W+SIFPVEN+ELV+G+WED++IWD   M  +  PKI++LD ND+N+IL IP+DIDP+T  +   +P+ KVKI   HV++S++LL ++G+I+V+E++SPPPP + +D DP+NISND YY  K T+ ++KVSTG  ++QH+TPVVELQAPF+PTH+  +KLR FHRPP+KR+S GPL      + V PL +HI+K AK RE ER  AGGG+IFFMRTP+D+SGKDG+L+L E+ EEH PL+  VGM S++KNYYKRK   D GP ++KYGE+  AHTSPFLGT+ PGQS+QA+ENNM+R+P++EH  P +DF++IRTRT + +REVD  + VGQECPLYEVPGPNSKRANNF RDFLQVFIYRLFWKS D P+RI+MD+IK+AFPAHSESSIRKRLK CA+F RTG DSNWWV++ +FRLP+EEE+R++V PE CCAYFSMIAAEQRL+DAGYGEKFLFA + +DDED  LKMDDE+KVAPWNTTRAY+ AMK KCLLQLTGPADPTG  GEGFSYVR+PNKP +NKEE E QPKR VTGTDADLR+L L +A+AILR +GVPE+EI  LSRW+VIDVVRTLSTEK KAGE+G  KFSRGNRFSIAEHQERY+++CQR+F +QNRVL S+EVLS+DE ES EEE+  D E   EMGKN+ENML+NKKTSSQ  REREE ERR LQKMI+GEGS + +K  S+ G     DE D SS    +      ++LKI RTFK  +GK++TR ELVRKP +I+TY+++R TKD+ FI+QFAT D+ QKEEMK+E+RRIQEQLRR+KRN+EKEKLG+  N++       K K DLK+ CGACG  GHMRTNK CP +      +    VAMTE  EE++EKQ+    E+EELVNVDGTKVKLS K+++HA++++R ++ LK+PK+A+     +KR R GTV HCDYL+    + A RRRTDP++T +T LE I N++R + +   FL PV+ K +P Y+ ++  PMDLQTIRENI++K+Y  RE+FLSDVN I+ NS ++NG + I T  AK+++DL I +LS+ E++ M+LEKAINPLLDD+DQVA +Y+LDNI+N K+K + E+WPF+KPVNKK  K YY IVKNPMDLET++ KV  ++YH+R EFL D++LI  NS+ YNGE S FT K   +  + R TLE
Sbjct:    3 NLTGFLFGNIDKEGKLEADILDEESKRQLGTLGRF-----GLMSIL--QNVIREDDSGSKDQSTDSEDDGAKSPTAEDYSDINEL------------------AEDEGGP----------------YLDDSILMPPPPTPTSKSLSASEAKKRLETPLAAMLPSKYANIDVRELFPDFRPDKVLCFSRLFGPGKPSSLPQIWRGVKKKRKKKKSPDSEDY-VEEEIEDVEITFKFGPP---PPPEKCRPDDEERFLKPLEDP------NALNNIKNSDDDKGPNVADWRFGPAQLWYDILGVPETGEEFDY----------------GFKVKRKDPNNVDEDGKDL-----------PGFKFPDEAFHMITQLNWEDDVVWNGDDIKHKVMQKLNAKGGLASGWLPTATNRLATQKATPAATPATGKAATPGAKGGAKSAANKPGGAAAAAAAAAAAAAAAAAVEEAADDVWHSIFPVENDELVFGQWEDDIIWDSENMKEMPKPKILTLDTNDENVILTIPDDIDPATKQAYVQQPV-KVKIPHPHVRKSKLLLGKAGVINVLEDDSPPPPSENNDKDPYNISNDEYYAAKATEAAIKVSTGGNIIQHSTPVVELQAPFIPTHLSIMKLRSFHRPPLKRYSHGPL-STPGPHPVHPLLRHIRKMAKQRELERMAAGGGDIFFMRTPDDLSGKDGDLILLEYCEEHPPLISQVGMSSRLKNYYKRKAVKDTGPPQYKYGETAYAHTSPFLGTLHPGQSIQAIENNMYRAPIYEHQLPSTDFLVIRTRTTYHVREVDAFYTVGQECPLYEVPGPNSKRANNFTRDFLQVFIYRLFWKSPDTPRRIRMDDIKRAFPAHSESSIRKRLKLCADFKRTGVDSNWWVLRPDFRLPSEEELRALVSPEQCCAYFSMIAAEQRLKDAGYGEKFLFAPEQDDDEDQQLKMDDEVKVAPWNTTRAYVQAMKNKCLLQLTGPADPTG-CGEGFSYVRVPNKPTINKEELESQPKRIVTGTDADLRRLSLNNAKAILRKHGVPEEEIKKLSRWEVIDVVRTLSTEKAKAGEEGMDKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLASNEVLSTDEGESEEEEDISDIE---EMGKNIENMLANKKTSSQLSREREEQERRELQKMILGEGSGSMKKDKSRVGL----DEEDSSSQPPLAGAGQAGRVLKIFRTFKNAEGKDYTRVELVRKPAIIDTYVRIRTTKDDAFIKQFATPDEHQKEEMKREKRRIQEQLRRLKRNQEKEKLGIVNNRRRK----VKMKPDLKMKCGACGQVGHMRTNKACPLY-QNTTPLPPMVVAMTEDQEEEIEKQIFS--EDEELVNVDGTKVKLSGKLVKHAEEIKRRSLVLKVPKEAM---SGRKRRRAGTVTHCDYLSRHTTKTANRRRTDPVVTLSTMLEEILNEMRELPDVQPFLFPVSSKTVPDYYRIVTRPMDLQTIRENIRQKRYQSREDFLSDVNLILENSTLYNGDKSILTTAAKRMLDLCIERLSQKEERFMRLEKAINPLLDDDDQVAFSYVLDNIINGKLKPLPEAWPFLKPVNKKFVKDYYTIVKNPMDLETVAKKVKAHKYHNREEFLYDVDLILENSIAYNGEESQFTEKARALGRICRDTLE 1552          

Query: 1502 VALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKI 1615
            V L+ +L+ ILNE ++ + +  PF+ PV+ K    YY IV  PMDL+TI   + + +Y SR +FLSD+ LI  NS  YNG+ S  TT   ++LD+    L +  +    LE+ I
Sbjct: 1330 VTLSTMLEEILNE-MRELPDVQPFLFPVSSKTVPDYYRIVTRPMDLQTIRENIRQKRYQSREDFLSDVNLILENSTLYNGDKSILTTAAKRMLDLCIERLSQKEERFMRLEKAI 1442          

Query:    3 NLTGFMFGNVDSSGNLDGDSVLGGLCGTSDVMRGLSSL--LSTKELLKDVLSVKEEE-------------------------GDLCEGEVVKAEDATDYGDIEEALSDEDSSSSEGGSENE--NEAEEEKGPAFGEEEGVD--------KETSAERTLDKILL------------DRSLMPPPSM-----------------------DKTRGDKSRRPLAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFGI-KASHRPRIWKGVKKRRKKKDIDNIEE------QGSKIKKLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAGDDSN---GKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXY-VSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSKT--AIPGIK---------------LQTMQQKRPINGDDTWYSIFPVENEELVYGRWEDEVIWDDGRMPRL-HPKIVSLDPNDDNIILGIPEDIDPSTLPSDE-PIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPK-TQESLKVSTGR-TLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKPV--NKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDE--HDESSSNNFSIGNKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEKLGLK-----------------------GNKKL-------------------------------SSKALAKA--KKDLKLVCGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQHADKLRRETVKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIA--------LEQTDIDSLGAALGVEEPPKKKRGRPRKKGPKIVSAEFIDVGSE---EAPGGSMEARHSEEAEGSGLL---------EEDLQYSS-EEDWEEV-----------VEEDNSSSFTVTVDPLDQQTPHAEDQVDPLVTMNFYXDNQATAGGEEELEVDENYDPSAFLHNLGKQLPTEIKEEDEYIPPPVAAQSAEDEN 1794
            NL GF+FGNVD +G+LDGD +        +  + LSSL  +     L DVL   + E                                 +KA+ A DY DI E L++E +      S+ E  +EA+EE       E+ +D            A  T D   +            D+ LMPPP+                         K +  K   PLAAMLP K++ +DVRE FP+FR +KVLRFSRLFG  K S  P+IW+ V++RR KK   +  +        S   + +    +   YA  P   + +  D  ++F     D+      KE +  G+ K       PK  DWR GPA+ WYD+L +P   ++F Y    A+ A +E   +   V D +                             PDDAF MV+Q++WE+DVVW+G+DIKHKVLQKLNSK NAAGW+PS+ +RTAG+FSQ  KT  A P                  +    QK     +D WYSIFPVEN+ELVY +WED+VIWD   + ++  PK+++LD ND+NIIL IP+DIDPS +  +  P  KVKI   HVK+S++LL ++G+I+V+ E++PPPPPK  D DP+NISNDV+Y  K T+ +LK+  G   LLQH+TP VEL+APFVPTH+GP+KLR+FHRPP+K++S G L        V+PLQKHIKKKAK RE ER  +GGG++FFMRTPED++G+DGEL+L EF EEH PL++ VGM SKIKN+YKRK   D GP +F++GE+  AHTSPFLG +  GQ +QA+ENNM+R+P++ HT   +DF++IRTR  + +RE+D LF  GQECPLYEVPGPNSKRANNF RDFLQVFIYRLFWKSRDNP++I+MD+IKKAFPAHSESSIRKRLK CA+F RTG DSN+WVIK  FRLP+EEEIR+MV PE CCAYFSMIAAEQRL+DAGYGEKF+FAQQ++DDE+  LKMDDE+KVAPWNTTRAYI AM+GKC+LQL GPADPTG  GEGFSYVR+PNKP   NKEE E QPKRTVTGTDADLR+L L +A+A+LR   VPE+EI  LSRW+VIDVVRTLSTEK KAGE+G  KFSRGNRFSIAEHQERY+++CQR+F +QNRVL SSEVLS+DE ES+  EE     D  E+GKNLENML+NKKTS+Q   EREE ER+ L + IM       E+ G  G  K K DE   DE  S+      KILKI RTFK  +G+E+TR ELVR+  VI+ Y+K+R TKDE FIRQFAT+D+  KEEMK+E+RRIQEQLRRIKRN++K  + ++                        N+ L                               SS +  KA  K DLKL CGACG  GHMRTNK CP++       S+ +VAMTE+ EE++EK+L  + +E +LVNVDGTKVKLS+K+L+  + ++R T+ LK+PK+AV     KKR R G   HCDYL   N +   R+RTDP++ F++ LE + N+LR M +   FL PVN K++  Y  +++ PMDLQTIR+N+++KKY  R+EFL D+NQIV NSA++NG +   T  A++L++     + E E++L +LEK+INPLLDD+DQVAL+YIL   +N ++KSM ESWPF+KPVNK+  K YY I++ PMDLE +S KV  ++YHSR +FL+D+ LI  NS QYNG  ++FT +  ++++  R  L+     + +LE  I  VQ  A         E  + +S G A G               G +  + +  D G++   + P  S +A  +  AE              +   QYS+ +E++EEV           +E+ N++S  +     D     AE  V  L +  +Y   Q     +E +E+D NYDPS FL    +Q   +    D  I     A  + D+N
Sbjct:   15 NLAGFLFGNVDENGHLDGDFL------DEEAKQQLSSLSRMGLSSFLADVLQDDDAEKPTRRPYSDSDDSSSSDDDRRRYDDDSDGANYKIKADCAVDYSDITE-LAEESAVPPPAVSKTEETDEAKEEDKKNIKVEDDIDDIEAAIPCTRVDARGTSDTTAVKEENASGADGVDDKDLMPPPTAPVSADGTTGTTGTSTTAATTDDASKDKPKKLETPLAAMLPSKYQNVDVREFFPDFRPDKVLRFSRLFGPGKISSLPQIWRSVRRRRNKKSQSSSRKPRDGSDSTSDSDEPRRRQYFTPTYASLPPK-DMWASDEELRFTSREADEEKEIKDKESDSKGDSK-------PKVADWRYGPAQKWYDMLDVPDTGEDFNYGFKQADPAKLEALPSVTSVTDNKA---------------------------FPDDAFLMVSQLHWEDDVVWDGNDIKHKVLQKLNSKVNAAGWLPSSGSRTAGAFSQPGKTLPASPASTGSKGSSGSKMSKTHMIINAAQKAQEENEDAWYSIFPVENDELVYDKWEDDVIWDAEAVTKIPKPKVLTLDANDENIILCIPDDIDPSKIVRNTGPQPKVKIPHPHVKKSKILLGKAGVINVLAEDTPPPPPKSPDRDPYNISNDVFYMAKSTEATLKIKVGGGNLLQHSTPTVELRAPFVPTHMGPMKLRMFHRPPMKKYSYGSLASSNP-QPVLPLQKHIKKKAKQRELERIASGGGDVFFMRTPEDLTGRDGELILIEFCEEHPPLMNQVGMASKIKNFYKRKMGKDPGPPEFRFGETHYAHTSPFLGILHHGQCIQAIENNMYRAPIYPHTIQETDFLVIRTRNNYFVREMDALFTAGQECPLYEVPGPNSKRANNFVRDFLQVFIYRLFWKSRDNPRKIRMDDIKKAFPAHSESSIRKRLKLCADFKRTGMDSNFWVIKPEFRLPSEEEIRAMVSPEQCCAYFSMIAAEQRLKDAGYGEKFIFAQQEDDDEEMQLKMDDEVKVAPWNTTRAYIQAMRGKCILQLNGPADPTG-CGEGFSYVRMPNKPTQQNKEETESQPKRTVTGTDADLRRLSLNNAKALLRKFQVPEEEIKKLSRWEVIDVVRTLSTEKAKAGEEGMDKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLASSEVLSTDEGESTASEE----SDLEELGKNLENMLANKKTSTQLSLEREEQERQELLRKIM-------EEQGGSGQKKKKDDEGMKDEQQSST----AKILKITRTFKNAEGREYTRVELVRRSPVIDAYVKIRTTKDEAFIRQFATLDEALKEEMKREKRRIQEQLRRIKRNQQKIGMQMQNPHSSVGTPISLGDRETNTPKPFANRMLDISGRSLDGSGAGPSGAGAAGTPGAGKEHSPSSSSRRKAKIKPDLKLKCGACGQVGHMRTNKACPQYSGILATPSL-NVAMTEEQEEEIEKELNAD-DEGDLVNVDGTKVKLSSKLLKRHEDVKRRTLLLKVPKEAV----GKKRRRVGGDSHCDYLQRHN-KTTNRQRTDPVVVFSSVLEQVLNELRDMQDVQPFLFPVNAKQVVDYHKIVQRPMDLQTIRDNVRQKKYQTRDEFLMDINQIVENSALYNGAKSSLTVAAQRLLERCKESIQEREERLTRLEKSINPLLDDDDQVALSYILGEYVNGQLKSMPESWPFLKPVNKRLVKDYYTIIRRPMDLEKVSKKVASHKYHSRIDFLADLHLIADNSDQYNGAEANFTKQARQMVEAARQALDAMEHSVAHLERNIALVQERARNEDDDMDWEDDEQESKGDAAG---------------GSRDTTPDLDDGGNDSNPDRPPSSTDASKAARAEAKRARARQRKAAKDDAGHQYSTDDEEFEEVGTSDNEGVSVTLEQSNTTSSMMPPQSEDDSQQAAEAMVQ-LSSAQYYNSAQ-----DESMEIDPNYDPSDFLGMSSRQQTGDSGRNDAGIQQSSEASYSVDQN 1915          

Query:    3 NLTGFMFGNVDSSGNLDGDSVLGGLCGT---SDVMRGLSSL--LSTKELLKDVLSVKEEE------------------------------GDLCEGEVVKAED-ATDYGDIEEALSDEDSSSSEGGSENENEAEEEKGPAFGEEEGVDKETSAERTLDKILLDRSLMPPPSMDKTRG---------------------------DKSRR---PLAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFGI-KASHRPRIWKGV-------KKRRKKKDIDNIEEQGSKIKKLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAGDDSNGKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSKTAIPGI-------------KLQTMQQKRPING-DDTWYSIFPVENEELVYGRWEDEVIWDDGRMPRL-HPKIVSLDPNDDNIILGIPEDIDPSTL-PSDEPIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQESLKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKPV-NKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFSIGNKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEKLG-LKGNKKLS-------------------------------SKALAKAKKDLKLVCGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQH--ADKLRRET-----VKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQTDIDSLGAALGVEEPPKKKRGRPRKKGPKIVSAE------------FIDVGSEEAPGGSMEARHSEEAEGSG--------------LLEEDLQYSS-------EEDWEEVVE-EDNSSSFTVTVDPLDQQTPHAEDQVDPLVTMNFYXDNQATAGGEEELEVDENYDPSAFL--HNLGKQL--PTEIK---------EEDEYIP--PPVAAQSAEDENDFGNST------YKEEPVD-------IKDDLDISDSDDNDE 1822
            +LTG +FGN+DS G L  D    G  GT   +++   + SL  L    +L +V+ +KE E                              G   E   VKA+D A DY DI E   D   +  E  S  ++   E+  PA   E  + K+            D+ LMPPPS     G                           D  R+   PLA +LP K++ +DVRELFP+FR  KVLRFSRLFG  K +  P+IW+ V        + R +K  +          +      +  +YA  P   E    D           D N ++   +G     +S + PK  DWR GPA+ WYD+L +P   + F Y     AAS     ++ ++KD+R  ++ E+  E      +PS         + DDAF MV+Q++WE+DVVW+G+DIK KVLQKLNSKTNAAGW+PS+ +RTAG+FSQ  K ++P               K Q   Q +P    DDTWYS+FPVENEEL+Y +WEDEVIWD  ++ ++  PK+++LDPND+NIILGIP+DIDPS +  S  P  K+KI   HVK+S++LL ++G+I+V+ E++PPPPPK  D DPFNISND YY PKT+ +L++  G  L+QH+TPVVEL+APFVPTH+GP+KLR FHRPP+K++S GP M  +  + V PL K I KKAK RE ER  +GGG++FFMR PED+SG+DG++VL EF EEH PL++ VGMCSKIKNYYKRK E D GP  F YGE   AHTSPFLG + PGQ +QA+ENNM+R+P++ H    +DF++IRTR  + IR V+ ++ VGQECPLYEVPGPNSKRANNF RDFLQVFIYRLFWKSRDNP+RI+MD+IK+AFPAHSESSIRKRLK CA+F RTG DSNWWVIK  FRLP+EEEIR+MV PE CCAYFSMIAAEQRL+DAGYGEKFLFA Q++DDE+  LK+DDE+KVAPWNTTRAYI AM+GKCLLQL+GPADPTG  GEGFSYVR+PNKP   KEEQE QPKR+VTGTDADLR+LPL+ A+ +LR   VPE+EI  LSRW+VIDVVRTLSTEK KAGE+G  KFSRGNRFSIAEHQERY+++CQR+F +QNRVL SSEVLS+DEAESS  EE        E+GKNLENMLSNKKTS+Q L    E   R      + E    P  SG   G+K K D   +  + N     +IL+I RTF+  DGKE+TR E VR+  VI+ YIK+R TKDEQFI+QFAT+D+QQKEEMK+E+RRIQEQLRRIKRN+E+E+L  L  N+KL                                S+   K K DLKL CGACG  GHMRTNK CP +      +S  + ++ +  +E  EK++   +++++LVNVDGTKV LS+K+L+    D  +R +       LK+P+ A+     KK+ R G   HCDYL   N + A RRRTDP++  ++ LE IHN+LR M +   FL PV+ K++P Y+ V+  PMDLQT+RE I++++Y  RE FL D+ QIV NS I+NGP+  +T  A+++       L+E EDKLM+LEKAINPLLDD+DQVAL++I D  L+ +IK + ESWPF+KPVNKKQ K YY ++K PMDLETI   +  ++YHSR E+L+DIELI +N  QYNG ++ +T    KIL+  +  L E+S+H   LE  I + Q  A E  +      A G ++    +  R    G   +  E               +G+E     +  A       G G               +EEDLQ S+       EED++EV E E+N++S     + ++      +   DP   +    D +A    +E ++VD NYDPS FL  H   + L  P+ ++         E+D+  P  P  A+ SA    D G           E PV+       I DDLDIS+SD+ D+
Sbjct:   19 DLTGILFGNIDSEGRLLQDDDGEGRGGTGFDAELRENIGSLSKLGLDSMLLEVIDLKEAEPPSDDEEEEDARPSAVSASEGMSAFDALKAGVKREDGAVKAQDDAIDYSDITELSEDCPRTPPEETSTYDDL--EDAIPASKVEAKLTKD------------DKELMPPPSAPMRSGSGGGIEEPAKSNDASSPSDDSKSTDSKDADRKLDTPLADILPSKYQNVDVRELFPDFRPQKVLRFSRLFGPGKPTSLPQIWRHVRKRRRKRNQSRDQKTTNTGGSDSPSDTEEPRKRGFSLHYAAEPTPAECMSDDEDKLL-----GDFNSEDVRPEGPDNGENSDQKPKVADWRFGPAQIWYDMLEVPDSGEGFNYGFKTKAASTS---SQPQLKDERRVKSPEDDVE------DPS---------IADDAFLMVSQLHWEDDVVWDGNDIKAKVLQKLNSKTNAAGWLPSSGSRTAGAFSQPGKPSMPVGSGSSKQGSGASSKKAQQNAQAKPAEAPDDTWYSLFPVENEELIYYKWEDEVIWDAQQVSKVPKPKVLTLDPNDENIILGIPDDIDPSKINKSTGPPPKIKIPHPHVKKSKILLGKAGVINVLAEDTPPPPPKSPDRDPFNISNDTYYTPKTEPTLRLKVGGNLIQHSTPVVELRAPFVPTHMGPMKLRAFHRPPLKKYSHGP-MAQSIPHPVFPLLKTIAKKAKQREVERIASGGGDVFFMRNPEDLSGRDGDIVLAEFCEEHPPLINQVGMCSKIKNYYKRKAEKDSGPQDFVYGEVAFAHTSPFLGILHPGQCIQAIENNMYRAPIYPHKMAHNDFLVIRTRNNYWIRSVNSIYTVGQECPLYEVPGPNSKRANNFTRDFLQVFIYRLFWKSRDNPRRIRMDDIKQAFPAHSESSIRKRLKQCADFKRTGMDSNWWVIKPEFRLPSEEEIRAMVSPEQCCAYFSMIAAEQRLKDAGYGEKFLFAPQEDDDEEAQLKLDDEVKVAPWNTTRAYIQAMRGKCLLQLSGPADPTG-CGEGFSYVRVPNKPTQTKEEQESQPKRSVTGTDADLRRLPLQRAKELLRQFKVPEEEIKKLSRWEVIDVVRTLSTEKAKAGEEGMDKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLASSEVLSTDEAESSASEESDL----EELGKNLENMLSNKKTSTQ-LSREREELERQELLRQLDEEHGGPSGSGGAKGAKGKDDPGQQMLATNNQ--GRILRITRTFRGNDGKEYTRVETVRRQPVIDAYIKIRTTKDEQFIKQFATLDEQQKEEMKREKRRIQEQLRRIKRNQERERLAQLAQNQKLQPGGMPTSLGDPKSSGGHSHKERDSGYKEVSPSRKKFKLKPDLKLKCGACGQVGHMRTNKACPLYSGMQSSLSQSNPSLADDFDEQSEKEM--TMDDDDLVNVDGTKVTLSSKILKRHGGDDGKRRSGSSSGFTLKVPRDAM----GKKKRRVGGDLHCDYLQRHN-KTANRRRTDPVVVLSSILEIIHNELRSMPDVSPFLFPVSAKKVPDYYRVVTKPMDLQTMREYIRQRRYTSREMFLEDLKQIVDNSLIYNGPQSAYTLAAQRMFSSCFELLAEREDKLMRLEKAINPLLDDDDQVALSFIFDK-LHSQIKQLPESWPFLKPVNKKQVKDYYTVIKRPMDLETIGKNIEAHRYHSRAEYLADIELIATNCEQYNGSDTRYTKFSKKILEYAQTQLIEFSEHCGQLENNIAKTQERARE--NAPEFDEAWGNDDYNFDRGSRASSPGDDYIDVEGHGGHASSSNSIHRSMGAEAGSSHTAPAVRKPAPPGPGEVKRGRGRPRKQRDPVEEDLQCSTDDEDDDEEEDFQEVSEDENNAASILDQGERINAPADAMDGMFDP-KNIKTEIDLEAHQMADESMDVDPNYDPSDFLAMHKQRQSLGEPSSLQGAFTNFLSHEQDDNGPYNPAEASTSAASGADLGMDASMAMQMAPEMPVNTMNNGMGIDDDLDISESDEEDD 1973          

Query:    3 NLTGFMFGNVDSSGNLDGDSVLGGLCGT---SDVMRGLSSL--LSTKELLKDVLSVKEEE------------------------------GDLCEGEVVKAED-ATDYGDIEEALSDEDSSSSEGGSENENEAEEEKGPAFGEEEGVDKETSAERTLDKILLDRSLMPPPSMDKTRG---------------------------DKSRR---PLAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFGI-KASHRPRIWKGV-------KKRRKKKDIDNIEEQGSKIKKLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAGDDSNGKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSKTAIP-------------GIKLQTMQQKRPING-DDTWYSIFPVENEELVYGRWEDEVIWDDGRMPRL-HPKIVSLDPNDDNIILGIPEDIDPSTL-PSDEPIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQESLKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKPV-NKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFSIGNKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEKLG-LKGNKKLS-------------------------------SKALAKAKKDLKLVCGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQH--ADKLRRET-----VKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQT----------------------------DID--------------SLGAALGVEE---------PP-----KKKRGRPRK-KGP--KIVSAEFIDVGSEEAPGGSMEARHSEEAEGSGLLEEDLQYSS-------EEDWEEVVE-EDNSSSFTVTVDPLDQQTPHAEDQVDPLVTMNFYXDNQATAGGEEELEVDENYDPSAFL--HNLGKQL--PTEIK---------EEDEYIP--PPVAAQSAEDENDFGNST------YKEEPVD-------IKDDLDISDSDDNDE 1822
            +LTG +FGN+DS G L  D    G  GT   +++   + SL  L    +L +V+ +KE E                              G   E   VKA+D A DY DI E   D   +  E  S  ++   E+  PA   E  + K+            D+ LMPPPS     G                           D  R+   PLA +LP K++ +DVRELFP+FR  KVLRFSRLFG  K +  P+IW+ V        + R +K  +          +      +  +YA  P   E    D           D N ++   +G     +S + PK  DWR GPA+ WYD+L +P   + F Y     AAS     ++ ++KD+R  ++ E+  E      +PS         + DDAF MV+Q++WE+DVVW+G+DIK KVLQKLNSKTNAAGW+PS+ +RTAG+FSQ  K ++P               K Q   Q +P    DDTWYS+FPVENEEL+Y +WEDEVIWD  ++ ++  PK+++LDPND+NIILGIP+DIDPS +  S  P  K+KI   HVK+S++LL ++G+I+V+ E++PPPPPK  D DPFNISND YY PKT+ +L++  G  L+QH+TPVVEL+APFVPTH+GP+KLR FHRPP+K++S GP M  +  + V PL K I KKAK RE ER  +GGG++FFMR PED+SG+DG++VL EF EEH PL++ VGMCSKIKNYYKRK E D GP  F YGE   AHTSPFLG + PGQ +QA+ENNM+R+P++ H    +DF++IRTR  + IR V+ ++ VGQECPLYEVPGPNSKRANNF RDFLQVFIYRLFWKSRDNP+RI+MD+IK+AFPAHSESSIRKRLK CA+F RTG DSNWWVIK  FRLP+EEEIR+MV PE CCAYFSMIAAEQRL+DAGYGEKFLFA Q++DDE+  LK+DDE+KVAPWNTTRAYI AM+GKCLLQL+GPADPTG  GEGFSYVR+PNKP   KEEQE QPKR+VTGTDADLR+LPL+ A+ +LR   VPE+EI  LSRW+VIDVVRTLSTEK KAGE+G  KFSRGNRFSIAEHQERY+++CQR+F +QNRVL SSEVLS+DEAESS  EE        E+GKNLENMLSNKKTS+Q L    E   R      + E    P  SG   G+K K D   +  + N     +IL+I RTF+  DGKE+TR E VR+  VI+ YIK+R TKDEQFI+QFAT+D+QQKEEMK+E+RRIQEQLRRIKRN+E+E+L  L  N+KL                                S+   K K DLKL CGACG  GHMRTNK CP +      +S  + ++ +  +E  EK++   +++++LVNVDGTKV LS+K+L+    D  +R +       LK+P+ A+     KK+ R G   HCDYL   N + A RRRTDP++  ++ LE IHN+LR M +   FL PV+ K++P Y+ V+  PMDLQT+RE I++++Y  RE FL D+ QIV NS I+NGP+  +T  A+++       L+E EDKLM+LEKAINPLLDD+DQVAL++I D  L+ +IK + ESWPF+KPVNKKQ K YY ++K PMDLETI   +  ++YHSR E+L+DIELI +N  QYNG ++ +T    KIL+  +  L E+S+H   LE  I + Q  A E                              D++              S+GA  G            PP     K+ RGRPRK + P  ++ S   +  G       S+ +  S     +  L+EDLQ S+       EED++EV E E+N++S     + ++      +   DP   +    D +A    +E ++VD NYDPS FL  H   + L  P+ ++         E+D+  P  P  A+ SA    D G           E PV+       I DDLDIS+SD+ D+
Sbjct:   19 DLTGILFGNIDSEGRLLQDDDGEGRGGTGFDAELRENIGSLSKLGLDSMLLEVIDLKEAEPPSDDEEEEDARPSAVSASEGMSAFDALKAGVKREDGAVKAQDDAIDYSDITELSEDCPRTPPEETSTYDDL--EDAIPASKVEAKLTKD------------DKELMPPPSAPMRSGSGGGIEEPAKSNDASSPSDDSKSTDSKDADRKLDTPLADILPSKYQNVDVRELFPDFRPQKVLRFSRLFGPGKPTSLPQIWRHVRKRRRKRNQSRDQKTTNTGGSDSPSDTEEPRKRGFSLHYAAEPTPAECMSDDEDKLL-----GDFNSEDVRPEGPDNGENSDQKPKVADWRFGPAQIWYDMLEVPDSGEGFNYGFKTKAASTS---SQPQLKDERRVKSPEDDVE------DPS---------IADDAFLMVSQLHWEDDVVWDGNDIKAKVLQKLNSKTNAAGWLPSSGSRTAGAFSQPGKPSMPVGSGSSKQGSGASSKKAQQNAQAKPAEAPDDTWYSLFPVENEELIYYKWEDEVIWDAQQVSKVPKPKVLTLDPNDENIILGIPDDIDPSKINKSTGPPPKIKIPHPHVKKSKILLGKAGVINVLAEDTPPPPPKSPDRDPFNISNDTYYTPKTEPTLRLKVGGNLIQHSTPVVELRAPFVPTHMGPMKLRAFHRPPLKKYSHGP-MAQSIPHPVFPLLKTIAKKAKQREVERIASGGGDVFFMRNPEDLSGRDGDIVLAEFCEEHPPLINQVGMCSKIKNYYKRKAEKDSGPQDFVYGEVAFAHTSPFLGILHPGQCIQAIENNMYRAPIYPHKMAHNDFLVIRTRNNYWIRSVNSIYTVGQECPLYEVPGPNSKRANNFTRDFLQVFIYRLFWKSRDNPRRIRMDDIKQAFPAHSESSIRKRLKQCADFKRTGMDSNWWVIKPEFRLPSEEEIRAMVSPEQCCAYFSMIAAEQRLKDAGYGEKFLFAPQEDDDEEAQLKLDDEVKVAPWNTTRAYIQAMRGKCLLQLSGPADPTG-CGEGFSYVRVPNKPTQTKEEQESQPKRSVTGTDADLRRLPLQRAKELLRQFKVPEEEIKKLSRWEVIDVVRTLSTEKAKAGEEGMDKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLASSEVLSTDEAESSASEESDL----EELGKNLENMLSNKKTSTQ-LSREREELERQELLRQLDEEHGGPSGSGGAKGAKGKDDPGQQMLATNNQ--GRILRITRTFRGNDGKEYTRVETVRRQPVIDAYIKIRTTKDEQFIKQFATLDEQQKEEMKREKRRIQEQLRRIKRNQERERLAQLAQNQKLQPGGMPTSLGDPKSSGGHSHKERDSGYKEVSPSRKKFKLKPDLKLKCGACGQVGHMRTNKACPLYSGMQSSLSQSNPSLADDFDEQSEKEM--TMDDDDLVNVDGTKVTLSSKILKRHGGDDGKRRSGSSSGFTLKVPRDAM----GKKKRRVGGDLHCDYLQRHN-KTANRRRTDPVVVLSSILEIIHNELRSMPDVSPFLFPVSAKKVPDYYRVVTKPMDLQTMREYIRQRRYTSREMFLEDLKQIVDNSLIYNGPQSAYTLAAQRMFSSCFELLAEREDKLMRLEKAINPLLDDDDQVALSFIFDK-LHSQIKQLPESWPFLKPVNKKQVKDYYTVIKRPMDLETIGKNIEAHRYHSRAEYLADIELIATNCEQYNGSDTRYTKFSKKILEYAQTQLIEFSEHCGQLENNIAKTQERARENAPEFDEAWGNDDYNFDRGSRASSPGDDYIDVEGHGGHASSSNSIHRSMGAEAGSSHTAPAVRKPAPPGPGEVKRGRGRPRKQRDPVEEVKSQNPVKRGRGRPRKDSLASNMSHTQ--AYFLDEDLQCSTDDEDDDEEEDFQEVSEDENNAASILDQGERINAPADAMDGMFDP-KNIKTEIDLEAHQMADESMDVDPNYDPSDFLAMHKQRQSLGEPSSLQGAFTNFLSHEQDDNGPYNPAEASTSAASGADLGMDASMAMQMAPEMPVNTMNNGMGIDDDLDISESDEEDD 2006          

Query:    3 NLTGFMFGNVDSSGNLDGDSVLGGLCGT---SDVMRGLSSL--LSTKELLKDVLSVKEEE------------------------------GDLCEGEVVKAED-ATDYGDIEEALSDEDSSSSEGGSENENEAEEEKGPAFGEEEGVDKETSAERTLDKILLDRSLMPPPSMDKTRG---------------------------DKSRR---PLAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFGI-KASHRPRIWKGV-------KKRRKKKDIDNIEEQGSKIKKLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAGDDSNGKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSKTAIP-------------GIKLQTMQQKRPING-DDTWYSIFPVENEELVYGRWEDEVIWDDGRMPRL-HPKIVSLDPNDDNIILGIPEDIDPSTL-PSDEPIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQESLKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKPV-NKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFSIGNKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEKLG-LKGNKKLS-------------------------------SKALAKAKKDLKLVCGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQH--ADKLRRET-----VKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQT----------------------------DID--------------SLGAALGVEE---------PP-----KKKRGRPRK-KGP--KIVSAEFIDVGSEEAPGGSMEARHSEEAEGSGLLEEDLQYSS-------EEDWEEVVEEDNSSSFTV---------------TVDPLDQQT------------PHAEDQ----VDPLVTMNFYXDNQATAGGEEELEVDENYDPSAFL--HNLGKQL--PTEIK---------EEDEYIP--PPVAAQSAEDENDFGNST------YKEEPVD-------IKDDLDISDSDDNDE 1822
            +LTG +FGN+DS G L  D    G  GT   +++   + SL  L    +L +V+ +KE E                              G   E   VKA+D A DY DI E   D   +  E  S  ++   E+  PA   E  + K+            D+ LMPPPS     G                           D  R+   PLA +LP K++ +DVRELFP+FR  KVLRFSRLFG  K +  P+IW+ V        + R +K  +          +      +  +YA  P   E    D           D N ++   +G     +S + PK  DWR GPA+ WYD+L +P   + F Y     AAS     ++ ++KD+R  ++ E+  E      +PS         + DDAF MV+Q++WE+DVVW+G+DIK KVLQKLNSKTNAAGW+PS+ +RTAG+FSQ  K ++P               K Q   Q +P    DDTWYS+FPVENEEL+Y +WEDEVIWD  ++ ++  PK+++LDPND+NIILGIP+DIDPS +  S  P  K+KI   HVK+S++LL ++G+I+V+ E++PPPPPK  D DPFNISND YY PKT+ +L++  G  L+QH+TPVVEL+APFVPTH+GP+KLR FHRPP+K++S GP M  +  + V PL K I KKAK RE ER  +GGG++FFMR PED+SG+DG++VL EF EEH PL++ VGMCSKIKNYYKRK E D GP  F YGE   AHTSPFLG + PGQ +QA+ENNM+R+P++ H    +DF++IRTR  + IR V+ ++ VGQECPLYEVPGPNSKRANNF RDFLQVFIYRLFWKSRDNP+RI+MD+IK+AFPAHSESSIRKRLK CA+F RTG DSNWWVIK  FRLP+EEEIR+MV PE CCAYFSMIAAEQRL+DAGYGEKFLFA Q++DDE+  LK+DDE+KVAPWNTTRAYI AM+GKCLLQL+GPADPTG  GEGFSYVR+PNKP   KEEQE QPKR+VTGTDADLR+LPL+ A+ +LR   VPE+EI  LSRW+VIDVVRTLSTEK KAGE+G  KFSRGNRFSIAEHQERY+++CQR+F +QNRVL SSEVLS+DEAESS  EE        E+GKNLENMLSNKKTS+Q L    E   R      + E    P  SG   G+K K D   +  + N     +IL+I RTF+  DGKE+TR E VR+  VI+ YIK+R TKDEQFI+QFAT+D+QQKEEMK+E+RRIQEQLRRIKRN+E+E+L  L  N+KL                                S+   K K DLKL CGACG  GHMRTNK CP +      +S  + ++ +  +E  EK++   +++++LVNVDGTKV LS+K+L+    D  +R +       LK+P+ A+     KK+ R G   HCDYL   N + A RRRTDP++  ++ LE IHN+LR M +   FL PV+ K++P Y+ V+  PMDLQT+RE I++++Y  RE FL D+ QIV NS I+NGP+  +T  A+++       L+E EDKLM+LEKAINPLLDD+DQVAL++I D  L+ +IK + ESWPF+KPVNKKQ K YY ++K PMDLETI   +  ++YHSR E+L+DIELI +N  QYNG ++ +T    KIL+  +  L E+S+H   LE  I + Q  A E                              D++              S+GA  G            PP     K+ RGRPRK + P  ++ S   +  G       S+ +  S     +  L+EDLQ S+       EED++EV E++N+++  +                 DP + +T            P  ED      + +V ++      A    +E ++VD NYDPS FL  H   + L  P+ ++         E+D+  P  P  A+ SA    D G           E PV+       I DDLDIS+SD+ D+
Sbjct:   19 DLTGILFGNIDSEGRLLQDDDGEGRGGTGFDAELRENIGSLSKLGLDSMLLEVIDLKEAEPPSDDEEEEDARPSAVSASEGMSAFDALKAGVKREDGAVKAQDDAIDYSDITELSEDCPRTPPEETSTYDDL--EDAIPASKVEAKLTKD------------DKELMPPPSAPMRSGSGGGIEEPAKSNDASSPSDDSKSTDSKDADRKLDTPLADILPSKYQNVDVRELFPDFRPQKVLRFSRLFGPGKPTSLPQIWRHVRKRRRKRNQSRDQKTTNTGGSDSPSDTEEPRKRGFSLHYAAEPTPAECMSDDEDKLL-----GDFNSEDVRPEGPDNGENSDQKPKVADWRFGPAQIWYDMLEVPDSGEGFNYGFKTKAASTS---SQPQLKDERRVKSPEDDVE------DPS---------IADDAFLMVSQLHWEDDVVWDGNDIKAKVLQKLNSKTNAAGWLPSSGSRTAGAFSQPGKPSMPVGSGSSKQGSGASSKKAQQNAQAKPAEAPDDTWYSLFPVENEELIYYKWEDEVIWDAQQVSKVPKPKVLTLDPNDENIILGIPDDIDPSKINKSTGPPPKIKIPHPHVKKSKILLGKAGVINVLAEDTPPPPPKSPDRDPFNISNDTYYTPKTEPTLRLKVGGNLIQHSTPVVELRAPFVPTHMGPMKLRAFHRPPLKKYSHGP-MAQSIPHPVFPLLKTIAKKAKQREVERIASGGGDVFFMRNPEDLSGRDGDIVLAEFCEEHPPLINQVGMCSKIKNYYKRKAEKDSGPQDFVYGEVAFAHTSPFLGILHPGQCIQAIENNMYRAPIYPHKMAHNDFLVIRTRNNYWIRSVNSIYTVGQECPLYEVPGPNSKRANNFTRDFLQVFIYRLFWKSRDNPRRIRMDDIKQAFPAHSESSIRKRLKQCADFKRTGMDSNWWVIKPEFRLPSEEEIRAMVSPEQCCAYFSMIAAEQRLKDAGYGEKFLFAPQEDDDEEAQLKLDDEVKVAPWNTTRAYIQAMRGKCLLQLSGPADPTG-CGEGFSYVRVPNKPTQTKEEQESQPKRSVTGTDADLRRLPLQRAKELLRQFKVPEEEIKKLSRWEVIDVVRTLSTEKAKAGEEGMDKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLASSEVLSTDEAESSASEESDL----EELGKNLENMLSNKKTSTQ-LSREREELERQELLRQLDEEHGGPSGSGGAKGAKGKDDPGQQMLATNNQ--GRILRITRTFRGNDGKEYTRVETVRRQPVIDAYIKIRTTKDEQFIKQFATLDEQQKEEMKREKRRIQEQLRRIKRNQERERLAQLAQNQKLQPGGMPTSLGDPKSSGGHSHKERDSGYKEVSPSRKKFKLKPDLKLKCGACGQVGHMRTNKACPLYSGMQSSLSQSNPSLADDFDEQSEKEM--TMDDDDLVNVDGTKVTLSSKILKRHGGDDGKRRSGSSSGFTLKVPRDAM----GKKKRRVGGDLHCDYLQRHN-KTANRRRTDPVVVLSSILEIIHNELRSMPDVSPFLFPVSAKKVPDYYRVVTKPMDLQTMREYIRQRRYTSREMFLEDLKQIVDNSLIYNGPQSAYTLAAQRMFSSCFELLAEREDKLMRLEKAINPLLDDDDQVALSFIFDK-LHSQIKQLPESWPFLKPVNKKQVKDYYTVIKRPMDLETIGKNIEAHRYHSRAEYLADIELIATNCEQYNGSDTRYTKFSKKILEYAQTQLIEFSEHCGQLENNIAKTQERARENAPEFDEAWGNDDYNFDRGSRASSPGDDYIDVEGHGGHASSSNSIHRSMGAEAGSSHTAPAVRKPAPPGPGEVKRGRGRPRKQRDPVEEVKSQNPVKRGRGRPRKDSLASNMSHTQ--AYFLDEDLQCSTDDEDDDEEEDFQEVSEDENNAASILDQGERINAPADAMDGMFDPKNIKTEIDLEAHQMAEEPIGEDDSQQVAEAMVQLSGVGGYYAQQQQDESMDVDPNYDPSDFLAMHKQRQSLGEPSSLQGAFTNFLSHEQDDNGPYNPAEASTSAASGADLGMDASMAMQMAPEMPVNTMNNGMGIDDDLDISESDEEDD 2037          

Query:    3 NLTGFMFGNVDSSGNLDGDSVLGGLCGT---SDVMRGLSSL--LSTKELLKDVLSVKEEE------------------------------GDLCEGEVVKAED-ATDYGDIEEALSDEDSSSSEGGSENENEAEEEKGPAFGEEEGVDKETSAERTLDKILLDRSLMPPPSMDKTRG---------------------------DKSRR---PLAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFGI-KASHRPRIWKGV-------KKRRKKKDIDNIEEQGSKIKKLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAGDDSNGKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSKTAIP-------------GIKLQTMQQKRPING-DDTWYSIFPVENEELVYGRWEDEVIWDDGRMPRL-HPKIVSLDPNDDNIILGIPEDIDPSTL-PSDEPIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQESLKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKPV-NKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFSIGNKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEKLG-LKGNKKLS-------------------------------SKALAKAKKDLKLVCGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQH--ADKLRRET-----VKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQTDIDSLGAALGVEEPPKKKRGRPRKKGPKIVSAE------------FIDVGSEEAPGGSMEARHSEEAEGSG--------------LLEEDLQYSS-------EEDWEEVVEEDNSSSFTV---------------TVDPLDQQT------------PHAEDQ----VDPLVTMNFYXDNQATAGGEEELEVDENYDPSAFL--HNLGKQL--PTEIK---------EEDEYIP--PPVAAQSAEDENDFGNST------YKEEPVD-------IKDDLDISDSDDNDE 1822
            +LTG +FGN+DS G L  D    G  GT   +++   + SL  L    +L +V+ +KE E                              G   E   VKA+D A DY DI E   D   +  E  S  ++   E+  PA   E  + K+            D+ LMPPPS     G                           D  R+   PLA +LP K++ +DVRELFP+FR  KVLRFSRLFG  K +  P+IW+ V        + R +K  +          +      +  +YA  P   E    D           D N ++   +G     +S + PK  DWR GPA+ WYD+L +P   + F Y     AAS     ++ ++KD+R  ++ E+  E      +PS         + DDAF MV+Q++WE+DVVW+G+DIK KVLQKLNSKTNAAGW+PS+ +RTAG+FSQ  K ++P               K Q   Q +P    DDTWYS+FPVENEEL+Y +WEDEVIWD  ++ ++  PK+++LDPND+NIILGIP+DIDPS +  S  P  K+KI   HVK+S++LL ++G+I+V+ E++PPPPPK  D DPFNISND YY PKT+ +L++  G  L+QH+TPVVEL+APFVPTH+GP+KLR FHRPP+K++S GP M  +  + V PL K I KKAK RE ER  +GGG++FFMR PED+SG+DG++VL EF EEH PL++ VGMCSKIKNYYKRK E D GP  F YGE   AHTSPFLG + PGQ +QA+ENNM+R+P++ H    +DF++IRTR  + IR V+ ++ VGQECPLYEVPGPNSKRANNF RDFLQVFIYRLFWKSRDNP+RI+MD+IK+AFPAHSESSIRKRLK CA+F RTG DSNWWVIK  FRLP+EEEIR+MV PE CCAYFSMIAAEQRL+DAGYGEKFLFA Q++DDE+  LK+DDE+KVAPWNTTRAYI AM+GKCLLQL+GPADPTG  GEGFSYVR+PNKP   KEEQE QPKR+VTGTDADLR+LPL+ A+ +LR   VPE+EI  LSRW+VIDVVRTLSTEK KAGE+G  KFSRGNRFSIAEHQERY+++CQR+F +QNRVL SSEVLS+DEAESS  EE        E+GKNLENMLSNKKTS+Q L    E   R      + E    P  SG   G+K K D   +  + N     +IL+I RTF+  DGKE+TR E VR+  VI+ YIK+R TKDEQFI+QFAT+D+QQKEEMK+E+RRIQEQLRRIKRN+E+E+L  L  N+KL                                S+   K K DLKL CGACG  GHMRTNK CP +      +S  + ++ +  +E  EK++   +++++LVNVDGTKV LS+K+L+    D  +R +       LK+P+ A+     KK+ R G   HCDYL   N + A RRRTDP++  ++ LE IHN+LR M +   FL PV+ K++P Y+ V+  PMDLQT+RE I++++Y  RE FL D+ QIV NS I+NGP+  +T  A+++       L+E EDKLM+LEKAINPLLDD+DQVAL++I D  L+ +IK + ESWPF+KPVNKKQ K YY ++K PMDLETI   +  ++YHSR E+L+DIELI +N  QYNG ++ +T    KIL+  +  L E+S+H   LE  I + Q  A E  +      A G ++    +  R    G   +  E               +G+E     +  A       G G               +EEDLQ S+       EED++EV E++N+++  +                 DP + +T            P  ED      + +V ++      A    +E ++VD NYDPS FL  H   + L  P+ ++         E+D+  P  P  A+ SA    D G           E PV+       I DDLDIS+SD+ D+
Sbjct:   19 DLTGILFGNIDSEGRLLQDDDGEGRGGTGFDAELRENIGSLSKLGLDSMLLEVIDLKEAEPPSDDEEEEDARPSAVSASEGMSAFDALKAGVKREDGAVKAQDDAIDYSDITELSEDCPRTPPEETSTYDDL--EDAIPASKVEAKLTKD------------DKELMPPPSAPMRSGSGGGIEEPAKSNDASSPSDDSKSTDSKDADRKLDTPLADILPSKYQNVDVRELFPDFRPQKVLRFSRLFGPGKPTSLPQIWRHVRKRRRKRNQSRDQKTTNTGGSDSPSDTEEPRKRGFSLHYAAEPTPAECMSDDEDKLL-----GDFNSEDVRPEGPDNGENSDQKPKVADWRFGPAQIWYDMLEVPDSGEGFNYGFKTKAASTS---SQPQLKDERRVKSPEDDVE------DPS---------IADDAFLMVSQLHWEDDVVWDGNDIKAKVLQKLNSKTNAAGWLPSSGSRTAGAFSQPGKPSMPVGSGSSKQGSGASSKKAQQNAQAKPAEAPDDTWYSLFPVENEELIYYKWEDEVIWDAQQVSKVPKPKVLTLDPNDENIILGIPDDIDPSKINKSTGPPPKIKIPHPHVKKSKILLGKAGVINVLAEDTPPPPPKSPDRDPFNISNDTYYTPKTEPTLRLKVGGNLIQHSTPVVELRAPFVPTHMGPMKLRAFHRPPLKKYSHGP-MAQSIPHPVFPLLKTIAKKAKQREVERIASGGGDVFFMRNPEDLSGRDGDIVLAEFCEEHPPLINQVGMCSKIKNYYKRKAEKDSGPQDFVYGEVAFAHTSPFLGILHPGQCIQAIENNMYRAPIYPHKMAHNDFLVIRTRNNYWIRSVNSIYTVGQECPLYEVPGPNSKRANNFTRDFLQVFIYRLFWKSRDNPRRIRMDDIKQAFPAHSESSIRKRLKQCADFKRTGMDSNWWVIKPEFRLPSEEEIRAMVSPEQCCAYFSMIAAEQRLKDAGYGEKFLFAPQEDDDEEAQLKLDDEVKVAPWNTTRAYIQAMRGKCLLQLSGPADPTG-CGEGFSYVRVPNKPTQTKEEQESQPKRSVTGTDADLRRLPLQRAKELLRQFKVPEEEIKKLSRWEVIDVVRTLSTEKAKAGEEGMDKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLASSEVLSTDEAESSASEESDL----EELGKNLENMLSNKKTSTQ-LSREREELERQELLRQLDEEHGGPSGSGGAKGAKGKDDPGQQMLATNNQ--GRILRITRTFRGNDGKEYTRVETVRRQPVIDAYIKIRTTKDEQFIKQFATLDEQQKEEMKREKRRIQEQLRRIKRNQERERLAQLAQNQKLQPGGMPTSLGDPKSSGGHSHKERDSGYKEVSPSRKKFKLKPDLKLKCGACGQVGHMRTNKACPLYSGMQSSLSQSNPSLADDFDEQSEKEM--TMDDDDLVNVDGTKVTLSSKILKRHGGDDGKRRSGSSSGFTLKVPRDAM----GKKKRRVGGDLHCDYLQRHN-KTANRRRTDPVVVLSSILEIIHNELRSMPDVSPFLFPVSAKKVPDYYRVVTKPMDLQTMREYIRQRRYTSREMFLEDLKQIVDNSLIYNGPQSAYTLAAQRMFSSCFELLAEREDKLMRLEKAINPLLDDDDQVALSFIFDK-LHSQIKQLPESWPFLKPVNKKQVKDYYTVIKRPMDLETIGKNIEAHRYHSRAEYLADIELIATNCEQYNGSDTRYTKFSKKILEYAQTQLIEFSEHCGQLENNIAKTQERARE--NAPEFDEAWGNDDYNFDRGSRASSPGDDYIDVEGHGGHASSSNSIHRSMGAEAGSSHTAPAVRKPAPPGPGEVKRGRGRPRKQRDPVEEDLQCSTDDEDDDEEEDFQEVSEDENNAASILDQGERINAPADAMDGMFDPKNIKTEIDLEAHQMAEEPIGEDDSQQVAEAMVQLSGVGGYYAQQQQDESMDVDPNYDPSDFLAMHKQRQSLGEPSSLQGAFTNFLSHEQDDNGPYNPAEASTSAASGADLGMDASMAMQMAPEMPVNTMNNGMGIDDDLDISESDEEDD 2004          

Query:    3 NLTGFMFGNVDSSGNLDGDSVLGGLCGT---SDVMRGLSSL--LSTKELLKDVLSVKEEE------------------------------GDLCEGEVVKAED-ATDYGDIEEALSDEDSSSSEGGSENENEAEEEKGPAFGEEEGVDKETSAERTLDKILLDRSLMPPPSMDKTRG---------------------------DKSRR---PLAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFGI-KASHRPRIWKGV-------KKRRKKKDIDNIEEQGSKIKKLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAGDDSNGKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSKTAIP-------------GIKLQTMQQKRPING-DDTWYSIFPVENEELVYGRWEDEVIWDDGRMPRL-HPKIVSLDPNDDNIILGIPEDIDPSTL-PSDEPIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQESLKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKPV-NKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFSIGNKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEKLG-LKGNKKLS-------------------------------SKALAKAKKDLKLVCGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQH--ADKLRRET-----VKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQTDIDSLGAALGVEEPPKKKRGRPRKKGPKIVSAE------------FIDVGSEEAPGGSMEARHSEEAEGSG--------------LLEEDLQYSS-------EEDWEEVVEEDNSSSFTV---------------TVDPLDQQT-------------PHAEDQ----VDPLVTMNFYXDNQATAGGEEELEVDENYDPSAFL--HNLGKQL--PTEIK---------EEDEYIP--PPVAAQSAEDENDFGNST------YKEEPVD-------IKDDLDISDSDDNDE 1822
            +LTG +FGN+DS G L  D    G  GT   +++   + SL  L    +L +V+ +KE E                              G   E   VKA+D A DY DI E   D   +  E  S  ++   E+  PA   E  + K+            D+ LMPPPS     G                           D  R+   PLA +LP K++ +DVRELFP+FR  KVLRFSRLFG  K +  P+IW+ V        + R +K  +          +      +  +YA  P   E    D           D N ++   +G     +S + PK  DWR GPA+ WYD+L +P   + F Y     AAS     ++ ++KD+R  ++ E+  E      +PS         + DDAF MV+Q++WE+DVVW+G+DIK KVLQKLNSKTNAAGW+PS+ +RTAG+FSQ  K ++P               K Q   Q +P    DDTWYS+FPVENEEL+Y +WEDEVIWD  ++ ++  PK+++LDPND+NIILGIP+DIDPS +  S  P  K+KI   HVK+S++LL ++G+I+V+ E++PPPPPK  D DPFNISND YY PKT+ +L++  G  L+QH+TPVVEL+APFVPTH+GP+KLR FHRPP+K++S GP M  +  + V PL K I KKAK RE ER  +GGG++FFMR PED+SG+DG++VL EF EEH PL++ VGMCSKIKNYYKRK E D GP  F YGE   AHTSPFLG + PGQ +QA+ENNM+R+P++ H    +DF++IRTR  + IR V+ ++ VGQECPLYEVPGPNSKRANNF RDFLQVFIYRLFWKSRDNP+RI+MD+IK+AFPAHSESSIRKRLK CA+F RTG DSNWWVIK  FRLP+EEEIR+MV PE CCAYFSMIAAEQRL+DAGYGEKFLFA Q++DDE+  LK+DDE+KVAPWNTTRAYI AM+GKCLLQL+GPADPTG  GEGFSYVR+PNKP   KEEQE QPKR+VTGTDADLR+LPL+ A+ +LR   VPE+EI  LSRW+VIDVVRTLSTEK KAGE+G  KFSRGNRFSIAEHQERY+++CQR+F +QNRVL SSEVLS+DEAESS  EE        E+GKNLENMLSNKKTS+Q L    E   R      + E    P  SG   G+K K D   +  + N     +IL+I RTF+  DGKE+TR E VR+  VI+ YIK+R TKDEQFI+QFAT+D+QQKEEMK+E+RRIQEQLRRIKRN+E+E+L  L  N+KL                                S+   K K DLKL CGACG  GHMRTNK CP +      +S  + ++ +  +E  EK++   +++++LVNVDGTKV LS+K+L+    D  +R +       LK+P+ A+     KK+ R G   HCDYL   N + A RRRTDP++  ++ LE IHN+LR M +   FL PV+ K++P Y+ V+  PMDLQT+RE I++++Y  RE FL D+ QIV NS I+NGP+  +T  A+++       L+E EDKLM+LEKAINPLLDD+DQVAL++I D  L+ +IK + ESWPF+KPVNKKQ K YY ++K PMDLETI   +  ++YHSR E+L+DIELI +N  QYNG ++ +T    KIL+  +  L E+S+H   LE  I + Q  A E  +      A G ++    +  R    G   +  E               +G+E     +  A       G G               +EEDLQ S+       EED++EV E++N+++  +                 DP + +T             P  ED      + +V ++      A    +E ++VD NYDPS FL  H   + L  P+ ++         E+D+  P  P  A+ SA    D G           E PV+       I DDLDIS+SD+ D+
Sbjct:   19 DLTGILFGNIDSEGRLLQDDDGEGRGGTGFDAELRENIGSLSKLGLDSMLLEVIDLKEAEPPSDDEEEEDARPSAVSASEGMSAFDALKAGVKREDGAVKAQDDAIDYSDITELSEDCPRTPPEETSTYDDL--EDAIPASKVEAKLTKD------------DKELMPPPSAPMRSGSGGGIEEPAKSNDASSPSDDSKSTDSKDADRKLDTPLADILPSKYQNVDVRELFPDFRPQKVLRFSRLFGPGKPTSLPQIWRHVRKRRRKRNQSRDQKTTNTGGSDSPSDTEEPRKRGFSLHYAAEPTPAECMSDDEDKLL-----GDFNSEDVRPEGPDNGENSDQKPKVADWRFGPAQIWYDMLEVPDSGEGFNYGFKTKAASTS---SQPQLKDERRVKSPEDDVE------DPS---------IADDAFLMVSQLHWEDDVVWDGNDIKAKVLQKLNSKTNAAGWLPSSGSRTAGAFSQPGKPSMPVGSGSSKQGSGASSKKAQQNAQAKPAEAPDDTWYSLFPVENEELIYYKWEDEVIWDAQQVSKVPKPKVLTLDPNDENIILGIPDDIDPSKINKSTGPPPKIKIPHPHVKKSKILLGKAGVINVLAEDTPPPPPKSPDRDPFNISNDTYYTPKTEPTLRLKVGGNLIQHSTPVVELRAPFVPTHMGPMKLRAFHRPPLKKYSHGP-MAQSIPHPVFPLLKTIAKKAKQREVERIASGGGDVFFMRNPEDLSGRDGDIVLAEFCEEHPPLINQVGMCSKIKNYYKRKAEKDSGPQDFVYGEVAFAHTSPFLGILHPGQCIQAIENNMYRAPIYPHKMAHNDFLVIRTRNNYWIRSVNSIYTVGQECPLYEVPGPNSKRANNFTRDFLQVFIYRLFWKSRDNPRRIRMDDIKQAFPAHSESSIRKRLKQCADFKRTGMDSNWWVIKPEFRLPSEEEIRAMVSPEQCCAYFSMIAAEQRLKDAGYGEKFLFAPQEDDDEEAQLKLDDEVKVAPWNTTRAYIQAMRGKCLLQLSGPADPTG-CGEGFSYVRVPNKPTQTKEEQESQPKRSVTGTDADLRRLPLQRAKELLRQFKVPEEEIKKLSRWEVIDVVRTLSTEKAKAGEEGMDKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLASSEVLSTDEAESSASEESDL----EELGKNLENMLSNKKTSTQ-LSREREELERQELLRQLDEEHGGPSGSGGAKGAKGKDDPGQQMLATNNQ--GRILRITRTFRGNDGKEYTRVETVRRQPVIDAYIKIRTTKDEQFIKQFATLDEQQKEEMKREKRRIQEQLRRIKRNQERERLAQLAQNQKLQPGGMPTSLGDPKSSGGHSHKERDSGYKEVSPSRKKFKLKPDLKLKCGACGQVGHMRTNKACPLYSGMQSSLSQSNPSLADDFDEQSEKEM--TMDDDDLVNVDGTKVTLSSKILKRHGGDDGKRRSGSSSGFTLKVPRDAM----GKKKRRVGGDLHCDYLQRHN-KTANRRRTDPVVVLSSILEIIHNELRSMPDVSPFLFPVSAKKVPDYYRVVTKPMDLQTMREYIRQRRYTSREMFLEDLKQIVDNSLIYNGPQSAYTLAAQRMFSSCFELLAEREDKLMRLEKAINPLLDDDDQVALSFIFDK-LHSQIKQLPESWPFLKPVNKKQVKDYYTVIKRPMDLETIGKNIEAHRYHSRAEYLADIELIATNCEQYNGSDTRYTKFSKKILEYAQTQLIEFSEHCGQLENNIAKTQERARE--NAPEFDEAWGNDDYNFDRGSRASSPGDDYIDVEGHGGHASSSNSIHRSMGAEAGSSHTAPAVRKPAPPGPGEVKRGRGRPRKQRDPVEEDLQCSTDDEDDDEEEDFQEVSEDENNAASILDQGERINAPADAMDGMFDPKNIKTEIDLEAHQMAAEEPIGEDDSQQVAEAMVQLSGVGGYYAQQQQDESMDVDPNYDPSDFLAMHKQRQSLGEPSSLQGAFTNFLSHEQDDNGPYNPAEASTSAASGADLGMDASMAMQMAPEMPVNTMNNGMGIDDDLDISESDEEDD 2005          

Query:    3 NLTGFMFGNVDSSGNLDGDSVLGGLCGT---SDVMRGLSSL--LSTKELLKDVLSVKEEE------------------------------GDLCEGEVVKAED-ATDYGDIEEALSD------EDSSSSEG------GSENENEAEEEKGPAFGEEEGV------DKETSAERTLDKILL--------------DRSLMPPPSMDKTRG---------------------------DKSRR---PLAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFGI-KASHRPRIWKGV-------KKRRKKKDIDNIEEQGSKIKKLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAGDDSNGKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSKTAIP-------------GIKLQTMQQKRPING-DDTWYSIFPVENEELVYGRWEDEVIWDDGRMPRL-HPKIVSLDPNDDNIILGIPEDIDPSTL-PSDEPIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQESLKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKPV-NKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFSIGNKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEKLG-LKGNKKLS-------------------------------SKALAKAKKDLKLVCGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQH--ADKLRRET-----VKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQT----------------------------DID--------------SLGAALGVEE---------PP-----KKKRGRPRK-KGP--KIVSAEFIDVGSEEAPGGSMEARHSEEAEGSGLLEEDLQYSS-------EEDWEEVVEEDNSSSFTV---------------TVDPLDQQT------------PHAEDQ----VDPLVTMNFYXDNQATAGGEEELEVDENYDPSAFL--HNLGKQL--PTEIK---------EEDEYIP--PPVAAQSAEDENDFGNST------YKEEPVD-------IKDDLDISDSDDNDE 1822
            +LTG +FGN+DS G L  D    G  GT   +++   + SL  L    +L +V+ +KE E                              G   E   VKA+D A DY DI E   D      E++S+ +        S+ E +  E+    F   +G+      D  T A   L   LL              D+ LMPPPS     G                           D  R+   PLA +LP K++ +DVRELFP+FR  KVLRFSRLFG  K +  P+IW+ V        + R +K  +          +      +  +YA  P   E    D           D N ++   +G     +S + PK  DWR GPA+ WYD+L +P   + F Y     AAS     ++ ++KD+R  ++ E+  E      +PS         + DDAF MV+Q++WE+DVVW+G+DIK KVLQKLNSKTNAAGW+PS+ +RTAG+FSQ  K ++P               K Q   Q +P    DDTWYS+FPVENEEL+Y +WEDEVIWD  ++ ++  PK+++LDPND+NIILGIP+DIDPS +  S  P  K+KI   HVK+S++LL ++G+I+V+ E++PPPPPK  D DPFNISND YY PKT+ +L++  G  L+QH+TPVVEL+APFVPTH+GP+KLR FHRPP+K++S GP M  +  + V PL K I KKAK RE ER  +GGG++FFMR PED+SG+DG++VL EF EEH PL++ VGMCSKIKNYYKRK E D GP  F YGE   AHTSPFLG + PGQ +QA+ENNM+R+P++ H    +DF++IRTR  + IR V+ ++ VGQECPLYEVPGPNSKRANNF RDFLQVFIYRLFWKSRDNP+RI+MD+IK+AFPAHSESSIRKRLK CA+F RTG DSNWWVIK  FRLP+EEEIR+MV PE CCAYFSMIAAEQRL+DAGYGEKFLFA Q++DDE+  LK+DDE+KVAPWNTTRAYI AM+GKCLLQL+GPADPTG  GEGFSYVR+PNKP   KEEQE QPKR+VTGTDADLR+LPL+ A+ +LR   VPE+EI  LSRW+VIDVVRTLSTEK KAGE+G  KFSRGNRFSIAEHQERY+++CQR+F +QNRVL SSEVLS+DEAESS  EE        E+GKNLENMLSNKKTS+Q L    E   R      + E    P  SG   G+K K D   +  + N     +IL+I RTF+  DGKE+TR E VR+  VI+ YIK+R TKDEQFI+QFAT+D+QQKEEMK+E+RRIQEQLRRIKRN+E+E+L  L  N+KL                                S+   K K DLKL CGACG  GHMRTNK CP +      +S  + ++ +  +E  EK++   +++++LVNVDGTKV LS+K+L+    D  +R +       LK+P+ A+     KK+ R G   HCDYL   N + A RRRTDP++  ++ LE IHN+LR M +   FL PV+ K++P Y+ V+  PMDLQT+RE I++++Y  RE FL D+ QIV NS I+NGP+  +T  A+++       L+E EDKLM+LEKAINPLLDD+DQVAL++I D  L+ +IK + ESWPF+KPVNKKQ K YY ++K PMDLETI   +  ++YHSR E+L+DIELI +N  QYNG ++ +T    KIL+  +  L E+S+H   LE  I + Q  A E                              D++              S+GA  G            PP     K+ RGRPRK + P  ++ S   +  G       S+ +  S     +  L+EDLQ S+       EED++EV E++N+++  +                 DP + +T            P  ED      + +V ++      A    +E ++VD NYDPS FL  H   + L  P+ ++         E+D+  P  P  A+ SA    D G           E PV+       I DDLDIS+SD+ D+
Sbjct:   19 DLTGILFGNIDSEGRLLQDDDGEGRGGTGFDAELRENIGSLSKLGLDSMLLEVIDLKEAEPPSDDEEEEDARPSAVSASEGMSAFDALKAGVKREDGAVKAQDDAIDYSDITELSEDCPRTPPEETSTYDDLEDAIPASKVEAKLREDIAQIF---KGLCNSCQSDTITFAPLRLGSDLLLYRENNSHFVAAKDDKELMPPPSAPMRSGSGGGIEEPAKSNDASSPSDDSKSTDSKDADRKLDTPLADILPSKYQNVDVRELFPDFRPQKVLRFSRLFGPGKPTSLPQIWRHVRKRRRKRNQSRDQKTTNTGGSDSPSDTEEPRKRGFSLHYAAEPTPAECMSDDEDKLL-----GDFNSEDVRPEGPDNGENSDQKPKVADWRFGPAQIWYDMLEVPDSGEGFNYGFKTKAASTS---SQPQLKDERRVKSPEDDVE------DPS---------IADDAFLMVSQLHWEDDVVWDGNDIKAKVLQKLNSKTNAAGWLPSSGSRTAGAFSQPGKPSMPVGSGSSKQGSGASSKKAQQNAQAKPAEAPDDTWYSLFPVENEELIYYKWEDEVIWDAQQVSKVPKPKVLTLDPNDENIILGIPDDIDPSKINKSTGPPPKIKIPHPHVKKSKILLGKAGVINVLAEDTPPPPPKSPDRDPFNISNDTYYTPKTEPTLRLKVGGNLIQHSTPVVELRAPFVPTHMGPMKLRAFHRPPLKKYSHGP-MAQSIPHPVFPLLKTIAKKAKQREVERIASGGGDVFFMRNPEDLSGRDGDIVLAEFCEEHPPLINQVGMCSKIKNYYKRKAEKDSGPQDFVYGEVAFAHTSPFLGILHPGQCIQAIENNMYRAPIYPHKMAHNDFLVIRTRNNYWIRSVNSIYTVGQECPLYEVPGPNSKRANNFTRDFLQVFIYRLFWKSRDNPRRIRMDDIKQAFPAHSESSIRKRLKQCADFKRTGMDSNWWVIKPEFRLPSEEEIRAMVSPEQCCAYFSMIAAEQRLKDAGYGEKFLFAPQEDDDEEAQLKLDDEVKVAPWNTTRAYIQAMRGKCLLQLSGPADPTG-CGEGFSYVRVPNKPTQTKEEQESQPKRSVTGTDADLRRLPLQRAKELLRQFKVPEEEIKKLSRWEVIDVVRTLSTEKAKAGEEGMDKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLASSEVLSTDEAESSASEESDL----EELGKNLENMLSNKKTSTQ-LSREREELERQELLRQLDEEHGGPSGSGGAKGAKGKDDPGQQMLATNNQ--GRILRITRTFRGNDGKEYTRVETVRRQPVIDAYIKIRTTKDEQFIKQFATLDEQQKEEMKREKRRIQEQLRRIKRNQERERLAQLAQNQKLQPGGMPTSLGDPKSSGGHSHKERDSGYKEVSPSRKKFKLKPDLKLKCGACGQVGHMRTNKACPLYSGMQSSLSQSNPSLADDFDEQSEKEM--TMDDDDLVNVDGTKVTLSSKILKRHGGDDGKRRSGSSSGFTLKVPRDAM----GKKKRRVGGDLHCDYLQRHN-KTANRRRTDPVVVLSSILEIIHNELRSMPDVSPFLFPVSAKKVPDYYRVVTKPMDLQTMREYIRQRRYTSREMFLEDLKQIVDNSLIYNGPQSAYTLAAQRMFSSCFELLAEREDKLMRLEKAINPLLDDDDQVALSFIFDK-LHSQIKQLPESWPFLKPVNKKQVKDYYTVIKRPMDLETIGKNIEAHRYHSRAEYLADIELIATNCEQYNGSDTRYTKFSKKILEYAQTQLIEFSEHCGQLENNIAKTQERARENAPEFDEAWGNDDYNFDRGSRASSPGDDYIDVEGHGGHASSSNSIHRSMGAEAGSSHTAPAVRKPAPPGPGEVKRGRGRPRKQRDPVEEVKSQNPVKRGRGRPRKDSLASNMSHTQ--AYFLDEDLQCSTDDEDDDEEEDFQEVSEDENNAASILDQGERINAPADAMDGMFDPKNIKTEIDLEAHQMAEEPIGEDDSQQVAEAMVQLSGVGGYYAQQQQDESMDVDPNYDPSDFLAMHKQRQSLGEPSSLQGAFTNFLSHEQDDNGPYNPAEASTSAASGADLGMDASMAMQMAPEMPVNTMNNGMGIDDDLDISESDEEDD 2080          

Query:    3 NLTGFMFGNVDSSGNLDGDSVLGGLCGTSDVMRGLSSL--LSTKELLKDVLS--VKEEEGDLCEGEVVKAEDATDYGDIEEALSDEDSSSSEGGSENENEAE---EEK----GPAFGEEEGVDKETSAERTLDKILLDRSLMPPPSM------------DKTRGDKSRRPLAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFGI-KASHRPRIWKGVKKRRKKKDIDNIEEQGSKI----KKLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAGDDSNGKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSK-TAIP---GIKLQT---------------------MQQKRPINGDDTWYSIFPVENEELVYGRWEDEVIWDDGRMPRL-HPKIVSLDPNDDNIILGIPEDIDPSTLPSDE-PIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQES---LKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKP-VNKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFSIGNKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEK---LGLKGNK---------KLSSKALAKAKKDLKLVCGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQHADKLRRETVKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQTDIDSLGAALGVEE-------PPKKKRGRPRKKGP----KIVSAEFIDV-GSEEAPGGSMEARHSEEAEGSGLLEEDLQYSSEEDWEEV---VEEDNSS-------------SFTVTVDPLDQQTPHAEDQVDPLVTMNFYXDNQATAGGEEELEVDENYDPSAFLHNLGKQLPTEIKEEDEYIPPPVAAQSAEDENDFGNSTYKEEPVDIKDDLDISDSDDNDEDAIEGSPVNKQSTSHSNVPPPPPLEETPDDDTLWF 1857
            N+TGF+FGN+D +G L+ D +       +D  + L+SL  L     L +++S     E+ +  +   +K E+ +D  DI+       S ++E  SE    A+   EE     G    E++ +D +   E  ++K   D+ LMPPP +            +  R  +   PLA+MLP K+  +DV E+FP+FR NKVLRFSRLFG  K S  P+IW+GV++RRKKK   +  +  S      ++LK    W+ NY       E    D   K   P  D   G++  + G   +      PK  DWR GPA+ WYD+L +P   D F Y         E+ D+     DK ++E E                         DDAF MV+Q++WE+DV+WNGD+IKHKV+QKLNSK N AGWVPS+ NRTA +FSQ  K T +P    ++L T                      QQ+R  N DDTWYSIFPVENEELVYG WE+EVIWD   M ++  PKI++LDPND+NI+LGIP+DIDP+ L  +  P  KVKI   HVK+S++LL ++G+I+V+EE++PPPPPK  D DPFNISND YY P++ E+   LKV  G  L+QH+TPVVEL+ PFV TH+G ++LR FHRPP++RFS GPL  +   +GV+PL KHIKKKAK RE ER  +GGG++FFMRTPED++GKDGELVL EF EEH PL++ VGMCSK+KNYYKRK   D+GP K+KYGE+  AHTSPFLG ++PGQS+QA+ENNM+R+P++EH  P +DF++IRTR ++ IRE+D LFV GQECPLYEVPGPNSKRANNF RDFLQVFIYRLFWKS+D P+RIKMD+IKKAFP+HSESSIRKRLK CA+F RTG DSNWWVIK +FRLP+EEEIR+MV PE CCAYFSM+AAEQRL+DAGYGEKFLF  QD+DDE+  LKMDDE+KVAPWNTTRAYI AMKGKCLLQL GPADPTG  GEGFSYVR+PNKP ++KEEQE QPKRTVTGTDADLR+L L +A+A+LR  GVPE+EI  LSRW+VIDVVRTLSTEK KAGE+G  KFSRGNRFSIAEHQERY+++CQR+F +QNRVL S+EVLS+DE ESS    D+D  D  EMGKN+ENMLSNKKTSSQ   EREE +R+ L+KM+MGE  E   K         ++D  ++    N   G ++LKI RTF+  DGKE+TR E+VRKP VI+TYIK+R +KDE FI+QFAT+D+QQKEEMK+E+RR+QEQLRRIKRN+E+EK    G   N          + ++        +LKL CGACG  GHMRTNK CP +        + +VAMTE+ EE++EKQL  N ++++LVNV+GTKVKLS+K+++HA++++R T+ LK+PK+AV    AKKR R    +HCDYL   + RPA RRRTDP++  +T LE I N++R + +   FL PV+ K +P Y+ +I+ PMDLQTIREN+++KKY  REEFL+DVNQIV NS ++NG +   T  AK+++D  + +L E ED+LM+LEKAINPLLDDNDQVALT+ILDN++N K+K+M E+WPF++PVNKK  K YY ++K PMDLETIS KV+ ++YHSR EF+ D+E I  N +QYNG++S FT K   ++ + + TL++Y DHLT LE  I  VQ+ A+EQ D+DS  + LG EE       P  +         P     I   +F+DV G  EA    + AR +  A+   +LEEDLQ+SSE++++EV    +E   S                V  D   QQ   A  Q   L  + FY   Q     EE ++VD NYDPS FL  L                PP A + + D+              I+DDL +S+SD+  E+ + G    KQ       PP  P EE   D  LWF
Sbjct:   16 NMTGFLFGNIDENGQLEDDIL------DNDAKQHLASLDRLGLGSFLNEMISHDSNGEKSEKKDKSNIKLENGSDNDDID---YQNKSPTAEDFSEINELADDIIEENVGINGTVKTEKDSIDYDADDEEHVNKS--DKQLMPPPPVPEEKDSLTPEEAEVARQRRLETPLASMLPSKYANIDVTEIFPDFRPNKVLRFSRLFGPGKPSSLPQIWRGVRRRRKKKRHHDTRDSDSGSDQDDRRLKFK-GWKMNYGQ-ESLSECIASDDEAKLLMPMEDKEQGRKAGESGENGDME----PKVADWRFGPAQIWYDMLEVPETGDGFNYGFKVG----EKKDSPTNGTDKLQDEDET----------------------FADDAFLMVSQLHWEDDVIWNGDEIKHKVMQKLNSKNNLAGWVPSSGNRTAQAFSQPGKGTPVPVASNVRLATSQISTPLHMQSHKNKAQGKSNHQQQREDNYDDTWYSIFPVENEELVYGLWEEEVIWDAENMKKIPKPKILTLDPNDENIVLGIPDDIDPALLHKENGPTPKVKIPHPHVKKSKLLLGKAGVINVLEEDAPPPPPKSPDRDPFNISNDTYYMPRSSETTLRLKVGGG-NLIQHSTPVVELRVPFVQTHMGAMRLRNFHRPPIRRFSHGPLA-HPGPHGVLPLLKHIKKKAKQREQERIASGGGDVFFMRTPEDLTGKDGELVLVEFSEEHPPLMNQVGMCSKVKNYYKRKAGKDQGPQKYKYGETAYAHTSPFLGILTPGQSIQAIENNMYRAPIYEHNIPQTDFLVIRTRQQYFIREIDALFVAGQECPLYEVPGPNSKRANNFVRDFLQVFIYRLFWKSQDTPRRIKMDDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVIKPDFRLPSEEEIRAMVSPEQCCAYFSMVAAEQRLKDAGYGEKFLFTPQDDDDEEMQLKMDDEVKVAPWNTTRAYIQAMKGKCLLQLAGPADPTG-CGEGFSYVRVPNKPTISKEEQEAQPKRTVTGTDADLRRLSLNNAKALLRKFGVPEEEIKKLSRWEVIDVVRTLSTEKAKAGEEGMTKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLSSAEVLSTDEGESS----DEDSSDIEEMGKNIENMLSNKKTSSQLSLEREEQQRQELRKMLMGETQEQEGKKPKDKKKDDEEDSREQGQGFNTQSG-RVLKIYRTFRDPDGKEYTRAEIVRKPAVIDTYIKIRNSKDETFIKQFATLDEQQKEEMKREKRRLQEQLRRIKRNQEREKSHGCGTSSNSFPPTSSMLDRSNTNTPTTTSTNLKLKCGACGNVGHMRTNKACPLYQNSLTTAPV-NVAMTEEQEEEIEKQL--NADDQDLVNVEGTKVKLSSKLIKHAEEMKRRTLLLKVPKEAVS---AKKRRRATGDDHCDYLKK-HQRPANRRRTDPVVVMSTILESILNEMRDLPDVQPFLFPVSAKAVPDYYKIIQRPMDLQTIRENLRQKKYQSREEFLADVNQIVENSNLYNGSKSSLTVAAKRMLDTCVERLGEKEDRLMRLEKAINPLLDDNDQVALTFILDNVVNSKLKTMAEAWPFLRPVNKKLVKDYYNVIKRPMDLETISKKVSAHKYHSRQEFVQDVEQILENCVQYNGKDSTFTRKAEVLVKICKETLDDYDDHLTQLENNISLVQQRAMEQADMDS--SWLGPEEENYTIVEPEYRSSQTNSPDNPFGKSSIDDFDFVDVEGDIEA---ELNAR-TAHAKKKDVLEEDLQFSSEDEFDEVPFTADEQGESGDLEALELGGMRDCGEVAADDDSQQAAEAMVQ---LGNVGFYVGEQQLIQQEESMDVDPNYDPSDFL--LAGL-------------PPRAEKVSTDK--------------IRDDLAVSESDEEHEN-VTGQI--KQEIQ----PPSQPDEEVAGD--LWF 1864          

Query:    3 NLTGFMFGNVDSSGNLDGD----SVLGGLCGTSDVMRGLSSLLSTKELLKDVLSVKEEEGDLCEGE------------VVKAEDATDYGDIEEALSD-EDSSSSEGGSENENEAEEEKGPAFGEEEGVDKETSAERTLDKILLDRSLMPPPSMDKTRGDKSRRPLAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFGI-KASHRPRIWKGVKKRRKK------KDIDNIEEQGSKIKKLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAGD-DSNGKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSKTA-IP---GIKLQT----------------------MQQKRPINGDDTWYSIFPVENEELVYGRWEDEVIWDDGRMPRL-HPKIVSLDPNDDNIILGIPEDIDPSTLPSDE-PIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQES---LKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKP-VNKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFSIGN-KILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEKLGLKGNKKLSSKALAKAKKDLKLVCGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQHADKLRRETVKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQTDIDS--LGA---ALGVEEPPKKKRGRPRKKGP----KIVSAEFIDVGSEEAPGGSMEA-RHSEEAEGSGLLEEDLQYSSEEDWEEVV-----EEDNSSSFTVTVDPL--------DQQTPHAEDQVDPLVTMNFYXDNQATAGGEEELEVDENYDPSAFLHNLGKQLPTEIKEEDEYIPPPVAAQSAEDENDFGNSTYKEEPVDIKDDLDISDSDDNDEDAIEGSPVNKQSTSHSNVPPPPPLEETPDDDTLWF 1857
            N+TGF+FGN+D +G L+ D         L   S +  GLSS +      +++   +++E D    E            V K+  A D+ DI E   D  + ++ +G  E  NE E +      +EE V+K  +       +  ++  +     +  R  K   PLA+MLP K+  ++V ELFP+FRANKVLRFSRLFG  K S  P+IW+GVKKRR+K      +D D+  +Q  K  K K    WE NY   P +PE    D   K   P  D +  GK G+   NG       GPK  DWR GPA+ WYD+L +    D F Y                ++ DK EE++++++ E                 +  DDAF MV+Q++WE+DV+WNGDDIKHKVLQKLNSK NAAGWVPS+ NRTA +FSQ  K A +P    ++L T                       QQ R  N DDTWYSIFPVENEELVYG WE+EVIWD   M ++  PKI++LDPND+NI+LGIP+DIDP+ L  D  P  KVKI   HVK+S++LL ++G+I+V+EE++PPPPPK  D DPFNISND YY P++ E+   LKV  G  L+QH+TPVVEL+ PF+ TH+G ++LR FHRPP++RFS GPL  +   + V+PL KHIKKKAK RE ER  +GGG++FFMRTPED++GKDGELVL EF EEH PL++ VGMCSK+KNYYKRK   D+GP K+KYGE+  AHTSPFLG ++PGQS+QA+ENNM+R+P++EH  P +DF++IRTR ++ IRE+D LFV GQECPLYEVPGPNSKRANNF RDFLQVFIYRLFWK+ + P+ IKMD+IKKAFP+HSESSIRKRLK CA+F RTG +SNWWVIK +FRLPTEEEIR+MV PE CC+YFSMIAAEQRL+DAGYGEKFLF  QD+DDE+  LKMDDE+KVAPWNTTRAYI AMKGKCLLQL GPADPTG  GEGFSY+R+PNKP ++KEEQE QPKRTVTGTDADLR+L L +A+A+LR  GVPE+EI  LSRW+VIDVVRTLSTEK KAGE+G  KFSRGNRFSIAEHQERY+++CQR+F +QNRVL S+EVLS+DE ESS    D+D  D  EMGKN+ENMLSNKKTS+Q   EREE +R  L+KM+MG+  E  +KS  K     +      S  NNF+    ++LKI RTF+  +GKEFTR ELVRKP VI+TYIK+R +KDE FI+QFAT+D+ QKEEMK+E+RRIQEQLRRIKRN+E+E++   G     + + +     LKL CGACG  GHMRTNK CP +        + +VAMTE+ EE++EKQL  N ++++LVNVDGTKVKLS+K+++HA++++R T+ LK+PK+AV    +KKR R    +HCDYL     RPA RRRTDP++  +T LE I N++R + +   FL PVN K +P Y+ +I+ PMDLQTIREN++ KKY  REEFL+DVNQIV NS ++NG +   T  AK++++  + +L E ED LM+LEKAINPLLDDNDQVALT+ILDN++N K+KSM E+WPF+KPVNKK  K YY ++K PMDLET+S KV+ ++YH+RHEFL DIE I  N   YNG+ S +T K   +  V + TL+EY +HLT LE  I  VQ+ A+EQ D+D   LGA      + EP  +       + P     +   EF+DV       G +E    S   +   +LEEDLQ+SSE++++EV      + +N+   T+ ++ +        D  +  A + +  L  + FY  +Q     +E ++VD NYDPS FL                     +A   A DE              I+DDL +S+S    ED  E S   KQ T       P P E+   D  LWF
Sbjct:   17 NMTGFLFGNIDDNGQLEDDILDPEAKQHLASLSRL--GLSSFIREMMPNENMTDDRDDEQDNKHEEETETIDENDINYVEKSPSALDFSDINELADDINEENNKQGIFERRNEKENDYDA--DDEEVVNKSDTQLMPPPPVPEEKEALTAEEAEAARQRKLETPLASMLPSKYANVNVTELFPDFRANKVLRFSRLFGPGKPSSLPQIWRGVKKRRRKKRHHDVRDSDSGSDQDEKKPKFK---GWEMNYGPDP-NPEMCCSDDEKKLLLPVEDKEQTGKTGDTGENGD-----MGPKVADWRFGPAQLWYDMLQVAETGDGFNYGF--------------KLSDKLEEQSDKDTTE-----------------EFSDDAFLMVSQLHWEDDVIWNGDDIKHKVLQKLNSKNNAAGWVPSSGNRTAQAFSQPGKGAPVPVASNVRLATSQITTPLHMQPQKNKMSMNKGSQQQTREENYDDTWYSIFPVENEELVYGLWEEEVIWDPENMIKIPKPKILTLDPNDENIVLGIPDDIDPALLHKDNGPQPKVKIPHPHVKKSKLLLGKAGVINVLEEDTPPPPPKSPDRDPFNISNDTYYMPRSSETTLRLKVGGG-NLIQHSTPVVELRVPFIQTHMGQMRLRNFHRPPLRRFSHGPLA-HPGPHSVLPLLKHIKKKAKQREQERIASGGGDVFFMRTPEDLTGKDGELVLVEFSEEHPPLMNQVGMCSKMKNYYKRKAGKDQGPQKYKYGETAYAHTSPFLGILTPGQSIQAIENNMYRAPIYEHKIPETDFMVIRTRQQYYIREMDALFVAGQECPLYEVPGPNSKRANNFVRDFLQVFIYRLFWKAHNTPRCIKMDDIKKAFPSHSESSIRKRLKLCADFKRTGMNSNWWVIKPDFRLPTEEEIRAMVSPEQCCSYFSMIAAEQRLKDAGYGEKFLFTPQDDDDEEMQLKMDDEVKVAPWNTTRAYIQAMKGKCLLQLAGPADPTG-CGEGFSYIRVPNKPTISKEEQEAQPKRTVTGTDADLRRLSLNNAKALLRKFGVPEEEIKKLSRWEVIDVVRTLSTEKAKAGEEGMTKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLSSNEVLSTDEGESS----DEDSSDIEEMGKNIENMLSNKKTSTQLSLEREEQQRHELRKMLMGDVQEQEKKSKEKKKDDEED-----SPVNNFNAQQGRVLKIYRTFRNSEGKEFTRVELVRKPAVIDTYIKIRNSKDETFIKQFATLDEAQKEEMKREKRRIQEQLRRIKRNQERERM--LGGPMTGNHSSSNIFDHLKLKCGACGNVGHMRTNKACPLYQNSITTAPV-NVAMTEEQEEEIEKQL--NTDDQDLVNVDGTKVKLSSKLIKHAEEMKRRTLLLKVPKEAV---NSKKRRRATGDDHCDYLKRQQ-RPANRRRTDPVVVMSTILESILNEMRDLPDVQPFLFPVNAKAVPDYYKIIQRPMDLQTIRENLRLKKYQSREEFLADVNQIVENSTLYNGAKSSLTVAAKRMLETCVERLGEKEDLLMRLEKAINPLLDDNDQVALTFILDNVVNNKLKSMTEAWPFLKPVNKKLVKDYYTVIKRPMDLETVSKKVSAHKYHNRHEFLRDIEQILENCTIYNGKESVYTNKAEMLAKVCKETLDEYDEHLTQLENSILLVQKRAIEQADMDPSWLGADEDNYTIVEPEFRGSQTSSPENPFGKSNMDDFEFVDVE------GDLEGDSRSANLKKKDVLEEDLQFSSEDEFDEVPFGTDEQSENAEMETLELNEVREGGVVLADDDSQQAAEAMVQLGNVGFYMADQQLLQQDESMDVDPNYDPSDFL---------------------LAGLPARDEKSENK---------IQDDLAVSES----EDEAEISAQQKQKTQQL----PQPEEDVGGD--LWF 1841          

Query:    3 NLTGFMFGNVDSSGNLDGDSVLGGLCGTSDVMRGLSSL--LSTKELLKDVLSVKEEEGDLCEGEVVKAE-DATDYGDIEEALSDEDSSSSEGGSENENEAEEEKGPAFGEEEGVDKETSAERTLDKIL-----------LDRSLMPPPSMDKTR-----------GDKSR--RPLAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFGI-KASHRPRIWKGVKKRRKK---KDIDNIEEQGSKIKKLKMSH-AWEFNYADFPEDPEAYEVDAAIKFHRP---AGDDSNGKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSKTAI---------------PGIKL--QTMQQKRP-INGDDTWYSIFPVENEELVYGRWEDEVIWDDGRMPRL-HPKIVSLDPNDDNIILGIPEDIDPSTLPSDE--PIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQES---LKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKPV-NKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFSIGNKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEKLGL---------KGNKKLS------------------------SKALAKAKKDLKLVCGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQHADKLRRETVKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQTDIDSLGAA---LGVEEPPKKKRGRPRKKG----PKIVSAEFIDV-----GSEEAPGGSMEARHSEEAEGSGLLEEDLQYSSEEDWEEVVE---EDNSSSFTVTVD-PL-----DQQTPHAEDQVDPLVTMNFYXDNQATAGG----EEELEVDENYDPSAFLHNLGKQLPTEIKEE---DEYIPPPVAAQSAEDENDFGNSTYKEEPVDIKDDLDISDSDDNDEDAIEGSPVNKQ 1833
            +LTGF+FGN++  G L+ D +       ++  + LS+L  L     LK+++ V     D  + +   +E   + +GD      +++S+S+E    NE+   E K P+  +   +++    E    K             +D  LMPPP +  T+           GDK +   PLAAMLP K+  ++V +LFP+FR  KVLRFSRLFG  K S  P IWK V+K+RK+   KD  N  +  S  +  K  H  W  +YA+ P  PE  + D   KF +P   A  DS  +  +KD  G        PK  DWR GPA+ WYD+L +P   + F Y                  K K ++  E         T E +E  EG   + PDDAF MVTQ++WE+DVVW+G+DIKHKVLQKLNSKTNAAGWVPS+ NRTA +FSQ  K  +               PG+K   Q + + RP    DDTWYSIFPVENE+LVYGRWED+VIWD   M  +  P I++LDPND+NIILGIP+DIDPS   + +  P+ KVKI   HVK+S++LL ++G+I+V++E++PPPPPK  + DPFNISNDVYY P++ E+   LKV  G  L+QH+TPVVEL+APF+ TH+G ++LR FHRPP+KRFS GPL  +   + V+PL KHIKKKAK RE+ER  +GGG++FFMRTPED++G+DG+++L EF EEH PL++ VGMCSKIKNYYKRK   D GP  +KYGE+  AHTSPFLG + PGQS+QA+ENNM+R+P++EH  P SDF++IRTR ++ IRE+D L+V GQ+CPLYEVPGPNSKRANNF RDFLQVFIYRLFWKSRDNP+RIKM++IKKAFP+HSESSIRKRLK CA+F RTG DSNWWVIK  FRLPTEEEIR+MV PE CCAYFSM+AAEQRL+DAGYGEKF+F   ++DDE+  LKMDDE+KVAPWNTTRAYI AMKGKCLLQLTGPADPTG  GEGFSYVR+PNKP  NKEEQE QPKRTVTGTDADLR+L L +A+A+LR  GVPE+EI  LSRW+VIDVVRTLSTEK KAGE+G  KFSRGNRFSIAEHQERY+++CQR+F +QNRVL S+EVLS+DE ESS+E     DED  EMGKN+ENML+NKKTS+Q   EREE ER+ L+KMIM    +  +          ++         N++   +ILKIVRTF+  +GKEFTR E VRKP VI+ Y+K+R TKD+ FIRQFAT+D+ QKEEMK+E+RRIQEQLRRIKRN+EKE+L L          G +KL                         S+   K K DLKL CGACG  GHMRTNK CP +        + +VAMTE+ EE++EKQL  N ++E+LVN+DGTKVKLS+K+L+HA++++R+T+ LK+PK+A+    AK+R R  +  HCDYL   N R A RRRTDP++  +T LE I N++R M +   FL PVNPK++  Y+ +++ PMDLQTIREN+++KKY  REEFL+DVNQIV NS ++NG +   T  A+++++  + +L E E++LM+LEKAINPLLDDNDQVALT+ILDN++N K+K+M ESWPF+KPVNKK  K YY I+K PMDLETIS KV  ++YHSRHEFL DIE I  N + YNG +S FT K  +++ + +ATL+EY +HLT LE KI   Q  A++  D   +G       + EP +  +             I   +++DV      SE+        R  ++ + + +LEEDLQ+SSEE+ +EV     EDN     ++ + P+     D  +  A + +  L +M +Y  N+         EE ++VD NYDPS FL +    LP   +EE   DE +  P                 ++  + I DDL +S+S+D   + +  +PV ++
Sbjct:   17 DLTGFLFGNINEQGQLESDVL------DTESQKQLSNLGKLGLGSTLKEMIGVDSIPKDDSDSDYDNSEGQKSKFGD-----ENKESNSAES-QNNEDSNFESKSPSAVDFSDINELAEEEEEEAKPENYDADDEHPNEIDNKLMPPPPVPTTKENSESIVTTDDGDKKKLETPLAAMLPSKYANVNVTDLFPDFRHGKVLRFSRLFGPGKPSSLPNIWKNVRKKRKRRKHKDSANQHDSDSNSEDEKPKHRGWFIDYAE-PPPPEQIQSDDEEKFLKPMENATVDSKAETQSKDDTG--------PKVADWRFGPAQIWYDMLEVPETGEGFNY----------------GFKLKEDQPPEP--------TPEATEPREGD--EFPDDAFLMVTQLHWEDDVVWDGNDIKHKVLQKLNSKTNAAGWVPSSGNRTAQAFSQPGKGGLLSGSSVRLPIPAPPLPGMKAKAQILNKPRPDPEQDDTWYSIFPVENEDLVYGRWEDDVIWDADNMKNIPKPSILTLDPNDENIILGIPDDIDPSKQIAGQATPV-KVKIPHPHVKKSKILLGKAGVINVLQEDTPPPPPKSPNRDPFNISNDVYYMPRSSETTMRLKVGGG-NLIQHSTPVVELRAPFIQTHMGLMRLRNFHRPPMKRFSHGPLA-HPGPHPVMPLVKHIKKKAKQREAERMASGGGDVFFMRTPEDLTGRDGDIILIEFCEEHPPLMNQVGMCSKIKNYYKRKAAKDSGPPSYKYGETAYAHTSPFLGILHPGQSIQAIENNMYRAPIYEHDKPCSDFLVIRTRQQYYIREIDALYVAGQQCPLYEVPGPNSKRANNFVRDFLQVFIYRLFWKSRDNPRRIKMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVIKPEFRLPTEEEIRAMVSPEQCCAYFSMVAAEQRLKDAGYGEKFIFTPAEDDDEEMQLKMDDEVKVAPWNTTRAYIQAMKGKCLLQLTGPADPTG-CGEGFSYVRVPNKPTQNKEEQESQPKRTVTGTDADLRRLSLNNAKALLRKFGVPEEEIKKLSRWEVIDVVRTLSTEKAKAGEEGMDKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLSSAEVLSTDEGESSDE---GSDEDIEEMGKNIENMLANKKTSTQLSLEREEQERQELRKMIMEGDEKKGKDKKKDDDDNQEQ--------TNYAQQGRILKIVRTFRDAEGKEFTRVETVRKPAVIDAYVKIRSTKDDAFIRQFATLDEAQKEEMKREKRRIQEQLRRIKRNQEKERLALGLAASSNPAAGGEKLGSNDSPSSQSFNISPNKSTVISPPKSRRKTKLKPDLKLKCGACGNVGHMRTNKACPLYQNSGSNAPM-NVAMTEEQEEEIEKQL--NTDDEDLVNIDGTKVKLSSKLLKHAEEMKRKTLLLKVPKEAM---NAKRRRRGMSDLHCDYLKRHN-RTANRRRTDPVVVLSTILENILNEMRDMPDVQPFLFPVNPKKVMDYYRIVQRPMDLQTIRENLRQKKYQSREEFLADVNQIVENSTLYNGAKSSLTVAAQRMLNKCVERLGEKEERLMRLEKAINPLLDDNDQVALTFILDNVINTKLKAMSESWPFLKPVNKKLVKDYYSIIKRPMDLETISKKVAAHKYHSRHEFLVDIEQILENCILYNGRDSPFTEKAEQLVKICKATLDEYDEHLTQLENKISLAQERAMQDDDQAWMGGEEENYTIAEPDRISQASSPDHSLFMKSNIDDYDYVDVEGGIQTSEDVTASVSRPRKRKKKDEAAILEEDLQFSSEEELDEVPLNEFEDNKGGLVISAEMPMEGVNADDDSQQAAEAMVQLGSMGYYQQNEGDGTDLVYKEESMDVDPNYDPSDFLMS---GLPMHKQEEIKIDETVLQP-----------------QDSAMKIHDDLAVSESEDEGGNNVGEAPVQEE 1879          

Query:    3 NLTGFMFGNVDSSGNLDGDSVLGGLCGTSDVMRGLSSLLST------KELL-------------------KDVLSVKEEEGDLCEGEVVKAEDATDYGDIEEALSDEDSSSSEGGSENENEAEEEKGPAFGEEEGVDKETSAERTLDKILLDRSLMPPPSM------------DKTRGDKSRRPLAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFGI-KASHRPRIWKGVKKRRKKKDI------DNIEEQGSKIKKLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAGD-DSNGKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQ----------------TSKTAIP-----GIKLQTM-----QQKRPINGDDTWYSIFPVENEELVYGRWEDEVIWDDGRMPRL-HPKIVSLDPNDDNIILGIPEDIDPSTLPSDE-PIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQES---LKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKP-VNKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFS-IGNKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEKLGLKG----------------------------------NKKLSSKA----LAKAKK-------DLKLVCGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQHADKLRRETVKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQTDIDSLGAALGVEEPPKKKRGRPRKKGPKIVSA------------EFIDVGSEEAPGGSM--EARHSEEAEGSGLLEEDLQYSSEEDWEEV-VEEDNSSSFT------------VTVDPLDQQTPHAEDQVDPLVTMNFYXDNQATAGGEEELEVDENYDPSAFL 1763
            N+TGF+FGN+D  G L+ D +       S+  R L+SL         +E++                   ++   VK E  D+   E  K+  A D+ DI E   D +   +E  S+ ++ A  +      +EEGV+K             D  LMPPP +            +  R  K   PLA+MLP K+  ++V ELFP+FR NKVLRFSRLFG  K S  P+IW+GV+KRRKKK        D+  +   +  K K    W+ +YA  P  P+    D   K   P  D +  GK G+        S+  GPK  DWR GPA+ WYD+L +P   D F Y                    K  E+TEE  K KD  T              PDD+F MV+Q++WE+DVVWNGDDIKHKV+QKLNSK NAAGWVPS+ NRTA +FSQ                TS+ A P       KL +M     QQ+R  N DDTWYSIFPVENEELVYG WE+EVIWD   M ++  PKI++LDPND+NI+LGIP+DIDP+ L  D  P  KVKI   HVK+S++LL ++G+I+V+EE++PPPPPK  D DPFNISND YY P++ E+   LKV  G  L+QH+TPVVEL+APFV TH+GP++LR FHRPP+KR+S GPL  +T  + V+PL KHIKKKAK RE ER  +GGG++FFMRTPED++G+DGE+VL EF EEH PL++ VGMCSK+KNYYKR+   D+GP ++KYGE   AHTSPFLG ++PGQS+QA+ENNM+R+P++EH  P +DF+IIRTR ++ +RE+D LF+ GQECPLYEVPGPNSKRANNF RDFLQVFIYRLFWKSRD P+RIKMD+IKKAFP+HSESSIRKRLK CA+F RTG DSNWWVIK +FRLPTEEEIR+MV PE CCAYFSMIAAEQRL+DAGYGEKFLF  QD+DDE+  LKMDDE+KVAPWNTTRAYI AM+GKCLLQL GPADPTG  GEGFSYVR+PNKP ++KEEQE QPKRTVTGTDADLR+L L +A+A+LR  GVPE+EI  LSRW+VIDVVRTLSTEK KAGE+G  KFSRGNRFSIAEHQERY+++CQR+F +QNRVL S+EVLS+DE ESS    D+D  D  EMGKN+ENMLSNKKTS+Q   EREE ER  L+KMIMG+  E  +KS  K               NN+     ++LKI RTF+  DGKEFTR ELVRKP VI+TYIK+R +KDE FI+QFAT+D+ QKEEMK+E+RRIQEQLRRIKRN+E+E++ L G                                  +  LSSK     ++ +K+       DLKL CGACG  GHMRTNK CP +        + +VAMTE+ EE++EKQL  N ++++LVNVDGTKVKLS+K+++HA++++R T+ LK+PK+AV    A+KR R    +HCDYL     RPA RRRTDP++  +T LE I N++R + +   FL PVN K +P Y+ +++ PMDLQTIREN+++KKY  R EFL+DVNQIV NS ++NG +   T  AK+++D  + +L E ED+LM+LEKAINPLLDDNDQVAL++ILDN++N K+KSM E+WPF+KPVNKK  K YY ++K PMDLE+IS KVT ++YHSRHEFL DI  I  N   YNG++S FT K   ++   + TL+EY DHLT LE  I  VQ+ A+EQ DIDS  + LG +E        P  +G +  S             +F+DV       G M  E   S  A+   +LEEDLQ+SSE++++EV    D  S  T            V   P D  +  A + +  L  + FY   Q     EE ++VD NYDPS FL
Sbjct:   32 NMTGFLFGNIDEDGQLEDDIL------DSEAKRHLASLGRLGLSSLLQEMIALDNEEQNEKENEKGENEDENKTRVKSESDDVNYLE--KSPTALDFSDINELAEDINEDDAEASSKKQDRAASDYDA--DDEEGVNKS------------DTQLMPPPPIPDEKEALTPEEAEAARQRKLETPLASMLPSKYANINVTELFPDFRPNKVLRFSRLFGPGKPSSLPQIWRGVRKRRKKKKHHDPKDSDSGSDHDERKPKFK---GWKMHYAPTPS-PDECIPDDEEKLLLPVEDKEQTGKTGDMGD-----SNDMGPKVADWRFGPAQIWYDMLEVPETGDGFNYGF------------------KLAEKTEEVCKSKDEDT-------------FPDDSFLMVSQLHWEDDVVWNGDDIKHKVMQKLNSKNNAAGWVPSSSNRTAQAFSQPGKGTPVPVAPNVRLATSQIATPLHMQSKSKLASMGKGSQQQQREENYDDTWYSIFPVENEELVYGLWEEEVIWDAEHMTKIPKPKILTLDPNDENIVLGIPDDIDPALLHKDNGPQPKVKIPHPHVKKSKLLLGKAGVINVLEEDAPPPPPKSPDRDPFNISNDSYYMPRSSETTLRLKVGGG-NLIQHSTPVVELRAPFVQTHMGPMRLRNFHRPPLKRYSHGPL-SHTGPHHVLPLLKHIKKKAKQREQERIASGGGDVFFMRTPEDLTGRDGEIVLIEFSEEHPPLMNQVGMCSKVKNYYKRRAGKDQGPMRYKYGEVAYAHTSPFLGILTPGQSIQAIENNMYRAPIYEHNGPETDFLIIRTRQQYFVREIDALFIAGQECPLYEVPGPNSKRANNFVRDFLQVFIYRLFWKSRDTPRRIKMDDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVIKPDFRLPTEEEIRAMVSPEQCCAYFSMIAAEQRLKDAGYGEKFLFTPQDDDDEEMQLKMDDEVKVAPWNTTRAYIQAMRGKCLLQLAGPADPTG-CGEGFSYVRVPNKPTISKEEQEAQPKRTVTGTDADLRRLSLNNAKALLRKFGVPEEEIKKLSRWEVIDVVRTLSTEKAKAGEEGMTKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLSSNEVLSTDEGESS----DEDSSDIEEMGKNIENMLSNKKTSTQLSLEREEQERHELRKMIMGDMQEQEKKSKEKKKDDEDD-----GPVNNYGPQQGRVLKIYRTFRNPDGKEFTRVELVRKPAVIDTYIKIRNSKDETFIKQFATLDEAQKEEMKREKRRIQEQLRRIKRNQERERM-LGGPVTNSFSSSNLFERSNLSTPPVSSSSILPLSNFQSSTLSSKHPKPEISPSKRKKPKLKPDLKLKCGACGNVGHMRTNKACPLYQNSLPTAPV-NVAMTEEQEEEIEKQL--NTDDQDLVNVDGTKVKLSSKLIKHAEEMKRRTLLLKVPKEAV---SARKRRRATGDDHCDYLKRQQ-RPANRRRTDPVVVMSTMLESILNEMRDLPDVQPFLFPVNAKVVPDYYKIVQRPMDLQTIRENLRQKKYQSRGEFLADVNQIVENSTLYNGVKSSLTVAAKRMLDTCVERLGEKEDRLMRLEKAINPLLDDNDQVALSFILDNVVNNKLKSMTEAWPFLKPVNKKMVKDYYNLIKRPMDLESISKKVTAHKYHSRHEFLMDIAQILKNCTLYNGKDSPFTQKAETLVKACKETLDEYDDHLTQLENNILLVQQRAMEQADIDS--SWLGPDE-ENYTIAEPEFRGSQTSSPDNPFGKSMMDDFDFVDV------EGDMDGELGRSGRAKKKDVLEEDLQFSSEDEFDEVPFGTDEQSEQTEMEALEVGEMREVGEVPADDDSQQAAEAMVQLSNVGFYTGEQQMLQQEESMDVDPNYDPSDFL 1851          

Query:    3 NLTGFMFGNVDSSGNLDGDSVLGGLCGTSDVMRGLSSL--LSTKELLKDVLS--VKEEEGDLCEGEVVKAEDATDYGDIEEALSDEDSSSSEGGSENENEAE---EEK----GPAFGEEEGVDKETSAERTLDKILLDRSLMPPPSM------------DKTRGDKSRRPLAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFGI-KASHRPRIWKGVKKRRKKKDIDNIEEQGSKI----KKLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAGDDSNGKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSK-TAIP---GIKLQT---------------------MQQKRPINGDDTWYSIFPVENEELVYGRWEDEVIWDDGRMPRL-HPKIVSLDPNDDNIILGIPEDIDPSTLPSDE-PIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQES---LKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKP-VNKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFSIGNKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEK---LGLKGN---------------------------KKLSSKALAK----------------AKKDLKLVCGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQHADKLRRETVKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQTDIDSLGAALGVE-------EPPKKKRGRPRKKGP----KIVSAEFIDV-GSEEAPGGSMEARHSEEAEGSGLLEEDLQYSSEEDWEEV---VEEDNSS-------------SFTVTVDPLDQQTPHAEDQVDPLVTMNFYXDNQATAGGEEELEVDENYDPSAFLHNLGKQLPTEIKEEDEYIPPPVAAQSAEDENDFGNSTYKEEPVDIKDDLDISDSDDNDEDAIEGSPVNKQSTSHSNVPPPPPLEETPDDDTLWF 1857
            N+TGF+FGN+D +G L+ D +       +D  + L+SL  L     L +++S     E+ +  +   +K E+ +D  DI+       S ++E  SE    A+   EE     G    E++ +D +   E  ++K   D+ LMPPP +            +  R  +   PLA+MLP K+  +DV E+FP+FR NKVLRFSRLFG  K S  P+IW+GV++RRKKK   +  +  S      ++LK    W+ NY       E    D   K   P  D   G++  + G   +      PK  DWR GPA+ WYD+L +P   D F Y         E+ D+     DK ++E E                         DDAF MV+Q++WE+DV+WNGD+IKHKV+QKLNSK N AGWVPS+ NRTA +FSQ  K T +P    ++L T                      QQ+R  N DDTWYSIFPVENEELVYG WE+EVIWD   M ++  PKI++LDPND+NI+LGIP+DIDP+ L  +  P  KVKI   HVK+S++LL ++G+I+V+EE++PPPPPK  D DPFNISND YY P++ E+   LKV  G  L+QH+TPVVEL+ PFV TH+G ++LR FHRPP++RFS GPL  +   +GV+PL KHIKKKAK RE ER  +GGG++FFMRTPED++GKDGELVL EF EEH PL++ VGMCSK+KNYYKRK   D+GP K+KYGE+  AHTSPFLG ++PGQS+QA+ENNM+R+P++EH  P +DF++IRTR ++ IRE+D LFV GQECPLYEVPGPNSKRANNF RDFLQVFIYRLFWKS+D P+RIKMD+IKKAFP+HSESSIRKRLK CA+F RTG DSNWWVIK +FRLP+EEEIR+MV PE CCAYFSM+AAEQRL+DAGYGEKFLF  QD+DDE+  LKMDDE+KVAPWNTTRAYI AMKGKCLLQL GPADPTG  GEGFSYVR+PNKP ++KEEQE QPKRTVTGTDADLR+L L +A+A+LR  GVPE+EI  LSRW+VIDVVRTLSTEK KAGE+G  KFSRGNRFSIAEHQERY+++CQR+F +QNRVL S+EVLS+DE ESS    D+D  D  EMGKN+ENMLSNKKTSSQ   EREE +R+ L+KM+MGE  E   K         ++D  ++    N   G ++LKI RTF+  DGKE+TR E+VRKP VI+TYIK+R +KDE FI+QFAT+D+QQKEEMK+E+RR+QEQLRRIKRN+E+EK    G   N                               S +LA                  K DLKL CGACG  GHMRTNK CP +        + +VAMTE+ EE++EKQL  N ++++LVNV+GTKVKLS+K+++HA++++R T+ LK+PK+AV    AKKR R    +HCDYL   + RPA RRRTDP++  +T LE I N++R + +   FL PV+ K +P Y+ +I+ PMDLQTIREN+++KKY  REEFL+DVNQIV NS ++NG +   T  AK+++D  + +L E ED+LM+LEKAINPLLDDNDQVALT+ILDN++N K+K+M E+WPF++PVNKK  K YY ++K PMDLETIS KV+ ++YHSR EF+ D+E I  N +QYNG++S FT K   ++ + + TL++Y DHLT LE  I  VQ+ A+EQ D+DS  + LG E       EP  +         P     I   +F+DV G  EA    + AR +  A+   +LEEDLQ+SSE++++EV    +E   S                V  D   QQ   A  Q   L  + FY   Q     EE ++VD NYDPS FL  L                PP A + + D+              I+DDL +S+SD+  E+ + G    KQ       PP  P EE   D  LWF
Sbjct:   16 NMTGFLFGNIDENGQLEDDIL------DNDAKQHLASLDRLGLGSFLNEMISHDSNGEKSEKKDKSNIKLENGSDNDDID---YQNKSPTAEDFSEINELADDIIEENVGINGTVKTEKDSIDYDADDEEHVNKS--DKQLMPPPPVPEEKDSLTPEEAEVARQRRLETPLASMLPSKYANIDVTEIFPDFRPNKVLRFSRLFGPGKPSSLPQIWRGVRRRRKKKRHHDTRDSDSGSDQDDRRLKFK-GWKMNYGQ-ESLSECIASDDEAKLLMPMEDKEQGRKAGESGENGDME----PKVADWRFGPAQIWYDMLEVPETGDGFNYGFKVG----EKKDSPTNGTDKLQDEDET----------------------FADDAFLMVSQLHWEDDVIWNGDEIKHKVMQKLNSKNNLAGWVPSSGNRTAQAFSQPGKGTPVPVASNVRLATSQISTPLHMQSHKNKAQGKSNHQQQREDNYDDTWYSIFPVENEELVYGLWEEEVIWDAENMKKIPKPKILTLDPNDENIVLGIPDDIDPALLHKENGPTPKVKIPHPHVKKSKLLLGKAGVINVLEEDAPPPPPKSPDRDPFNISNDTYYMPRSSETTLRLKVGGG-NLIQHSTPVVELRVPFVQTHMGAMRLRNFHRPPIRRFSHGPLA-HPGPHGVLPLLKHIKKKAKQREQERIASGGGDVFFMRTPEDLTGKDGELVLVEFSEEHPPLMNQVGMCSKVKNYYKRKAGKDQGPQKYKYGETAYAHTSPFLGILTPGQSIQAIENNMYRAPIYEHNIPQTDFLVIRTRQQYFIREIDALFVAGQECPLYEVPGPNSKRANNFVRDFLQVFIYRLFWKSQDTPRRIKMDDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVIKPDFRLPSEEEIRAMVSPEQCCAYFSMVAAEQRLKDAGYGEKFLFTPQDDDDEEMQLKMDDEVKVAPWNTTRAYIQAMKGKCLLQLAGPADPTG-CGEGFSYVRVPNKPTISKEEQEAQPKRTVTGTDADLRRLSLNNAKALLRKFGVPEEEIKKLSRWEVIDVVRTLSTEKAKAGEEGMTKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLSSAEVLSTDEGESS----DEDSSDIEEMGKNIENMLSNKKTSSQLSLEREEQQRQELRKMLMGETQEQEGKKPKDKKKDDEEDSREQGQGFNTQSG-RVLKIYRTFRDPDGKEYTRAEIVRKPAVIDTYIKIRNSKDETFIKQFATLDEQQKEEMKREKRRLQEQLRRIKRNQEREKSHGCGTSSNSFPPTSSMLDRSNTNTPTTTSTSILPFNNFPSTSLASKHPKSETTPSKRKKPKLKPDLKLKCGACGNVGHMRTNKACPLYQNSLTTAPV-NVAMTEEQEEEIEKQL--NADDQDLVNVEGTKVKLSSKLIKHAEEMKRRTLLLKVPKEAV---SAKKRRRATGDDHCDYL-KKHQRPANRRRTDPVVVMSTILESILNEMRDLPDVQPFLFPVSAKAVPDYYKIIQRPMDLQTIRENLRQKKYQSREEFLADVNQIVENSNLYNGSKSSLTVAAKRMLDTCVERLGEKEDRLMRLEKAINPLLDDNDQVALTFILDNVVNSKLKTMAEAWPFLRPVNKKLVKDYYNVIKRPMDLETISKKVSAHKYHSRQEFVQDVEQILENCVQYNGKDSTFTRKAEVLVKICKETLDDYDDHLTQLENNISLVQQRAMEQADMDS--SWLGPEEENYTIVEPEYRSSQTNSPDNPFGKSSIDDFDFVDVEGDIEA---ELNAR-TAHAKKKDVLEEDLQFSSEDEFDEVPFTADEQGESGDLEALELGGMRDCGEVAADDDSQQAAEAMVQ---LGNVGFYVGEQQLIQQEESMDVDPNYDPSDFL--LAGL-------------PPRAEKVSTDK--------------IRDDLAVSESDEEHEN-VTGQI--KQEIQ----PPSQPDEEVAGD--LWF 1898          

Query:    3 NLTGFMFGNVDSSGNLDGD----SVLGGLCGTSDVMRGLSSLLSTKELLKDVLSVKEEE---------------GDLCEGEVVKAEDATDYGDIEEALSDE-DSSSSEGGSENENEAEEEKGPAFGEEEGVDKETSAERTLDKILLDRSLMPPPSMDKTRGDKSRRPLAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFGI-KASHRPRIWKGVKKRRKKK---DIDNIEEQGSKIKKLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAGD-DSNGKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSK----TAIPGIKLQTMQQKRPING--------------------DDTWYSIFPVENEELVYGRWEDEVIWDDGRMPRL-HPKIVSLDPNDDNIILGIPEDIDPSTLPSDE-PIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQES---LKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKP-VNKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFSIGN-KILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEKLGLKGNKKLS----------------SKALAKAKKDLKLVCGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQHADKLRRETVKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQTDIDSLGAA-----LGVEEPPKKKRGRPRKKGP----KIVSAEFIDVGSEEAPGGSMEARHSEEAEGSGLLEEDLQYSSEEDWEEV--VEEDNS----------SSFTVTVDPLDQQTPHAEDQVDPLVTMNFYXDNQATAGGEEELEVDENYDPSAFL 1763
            N+TGF+FGN+D +G L+ D         L   S +  GLSS ++  E++ +  + +E E                D+    +VK+  A D+ DI E   D  D  S   G + + + E     A  +EE V K  +       I  ++  +     +  R  K   PLA+MLP K+  +DV ELFP+FRANKVLRFSRLFG  K S  P+IW+GV+KRRKKK   D+ + +    +  K      W   Y   P   EA   D   K  RP  D +  GK G    NG       GPK  DWR GPA+ WYD+L +P   D F Y         E+ + K E KD+                            D  DDAF MV+Q++WE+DVVWNGDDIKHKV+QKLNSK NAAGWVPS+ NRTA +FSQ  K    T  P ++L T Q   P++                     DDTWYSIFPVENEELVYG WE+EVIWD   M ++  PKI++LDPND+NI+LGIP+DIDP+ L  D  P  KVKI   HVK+S++LL ++G+I+V+EE++PPPPPK  D DPFNISND YY PK+ E+   LKV  G  L+QH+TPVVEL+ PFV TH+GP++LR FHRPP++RFS GPL    A +GV+PL KHIKKKAK RE ER  +GGG++FFMRTPED++G+DGELVL EF EEH PL++ VGMCSK+KNYYKR+   D+GP  +KYGE+  AHTSPFLG ++PGQS+QA+ENNM+R+P++EH  P +DF++IR+R ++ IRE+D LFV GQECPLYEVPGPNSKRANNF RDFLQVFIYRLFW S D P+RI+MD+IKKAFP+HSESSIRKRLK CA+F RTG DSNWWVIK +FRLPTEEEIR+MV PE CCAYFSMIAAEQRL+DAGYGEKFLF  QD+DDED  LKMDDE+KVAPWNTTRAYI AMKGKCLLQL GPADPTG  GEGFSYVR+PNKP ++KEEQE QPKRTVTGTDADLR+L L +A+A+LR  GVPE+EI  LSRW+VIDVVRTLSTEK KAGE+G  KFSRGNRFSIAEHQERY+++CQR+F +QNRVL S+EVLS+DE ESSEE+         EMGKN+ENMLSNKKTS+Q   EREE +R  L+KM+MGE     E+   KG    KKDE ++S  NNF+    ++LKI RTF+  +GKE+TR ELVRKP VI+TYIK+R +KDE FI+QFAT+D+ QKEEMK+E+RRIQEQLRRIKRN+E+E++ L G+  ++                +     +  +LKL CGACG  GHMRTNK CP +        + +VAMTE+ EE++EKQL  N ++++LVNVDGTKVKLS+K+++HA++++R T+ LK+PK+AV    +KKR +  T +HCDYL   + RP  RRRTDP++  +T LE I N++R + +   FL PVN K +P Y  +I+ PMDLQTIREN++ KKY  REEFL+DVNQIV NS ++NG +   T  AK+++D  + +L E ED+LM+LEKAINPLLDDNDQVALT+ILDN++N K+KSM E WPFMKPVNKK  K YY IVK PMDLET+S KV+ ++YHSR EFL DIE I  N   YNG+ S  T+K   ++ V + TL+EY +HLT LE  I  VQ+ A+EQ DIDS           + EP  +         P     I   +F+DV       G ME      ++   +LEEDLQ+SSE++++EV  V +D+S          S     V   D  +  A + +  L  + FY   Q     +E ++VD NYDPS FL
Sbjct:   17 NITGFLFGNIDDNGQLEDDILDPDAKQHLASLSRL--GLSSFIN--EMMSNDNNAEERETGKVNEKKEDQNTTTNDMDVDYLVKSPTALDFSDINELAEDTIDEISKSNGFDRKLDKENADYDA-DDEEVVSKSDTQLMPPPPIPEEKETLTAEEAEAARQRKLETPLASMLPSKYANIDVTELFPDFRANKVLRFSRLFGPGKPSSLPQIWRGVRKRRKKKKHHDVRDSDSGSDQDDKKSKFKGWIMQYGPEPS-AEACRSDDENKLLRPVEDKEQTGKMGESGENGD-----MGPKVADWRFGPAQLWYDMLEVPETGDGFNY-GFKMVEKAEEQENKLETKDE----------------------------DFTDDAFLMVSQLHWEDDVVWNGDDIKHKVMQKLNSKNNAAGWVPSSGNRTAQAFSQPGKGASVTVTPNVRLATSQITTPLHMQSQKNKMNMGKGNQQPQREEDDTWYSIFPVENEELVYGLWEEEVIWDPEHMKKIPKPKILTLDPNDENIVLGIPDDIDPALLHKDNGPQPKVKIPHPHVKKSKLLLGKAGVINVLEEDTPPPPPKSPDRDPFNISNDTYYMPKSSETTLRLKVGGG-NLIQHSTPVVELRVPFVQTHMGPMRLRNFHRPPLRRFSYGPLA-LPAPHGVLPLLKHIKKKAKQREQERIASGGGDVFFMRTPEDLTGRDGELVLLEFSEEHPPLMNQVGMCSKVKNYYKRRAGKDQGPQTYKYGETAYAHTSPFLGILTPGQSIQAIENNMYRAPLYEHKIPETDFLVIRSRQQYYIREIDALFVAGQECPLYEVPGPNSKRANNFVRDFLQVFIYRLFWNSTDTPRRIRMDDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVIKPDFRLPTEEEIRAMVSPEQCCAYFSMIAAEQRLKDAGYGEKFLFTPQDDDDEDMQLKMDDEVKVAPWNTTRAYIQAMKGKCLLQLAGPADPTG-CGEGFSYVRVPNKPTISKEEQEAQPKRTVTGTDADLRRLSLNNAKALLRKFGVPEEEIKKLSRWEVIDVVRTLSTEKAKAGEEGMTKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLSSNEVLSTDEGESSEEDSSDI----EEMGKNIENMLSNKKTSTQLSLEREEQQRHELRKMLMGEAQ---EQESKKGKENKKKDEEEDSPVNNFNAQQGRVLKIYRTFRNSEGKEYTRVELVRKPAVIDTYIKIRNSKDETFIKQFATLDEAQKEEMKREKRRIQEQLRRIKRNQERERM-LGGSSIVNGSNINNSSNIFDRNNINTPTTTSSTNLKLKCGACGNVGHMRTNKACPLYQNSIATAPV-NVAMTEEQEEEIEKQL--NTDDQDLVNVDGTKVKLSSKLIKHAEEVKRRTLLLKVPKEAV---NSKKRRKPPTDDHCDYLKR-HQRPVNRRRTDPVVVMSTMLESILNEMRDLPDVQPFLFPVNAKVVPDYHKIIQRPMDLQTIRENLRLKKYQSREEFLADVNQIVENSTLYNGAKSSLTVAAKRMLDTCVERLGEKEDRLMRLEKAINPLLDDNDQVALTFILDNVVNNKLKSMTEVWPFMKPVNKKMVKDYYNIVKKPMDLETVSKKVSAHKYHSRQEFLRDIEQILENCSIYNGKESPLTSKAELLVKVCKDTLDEYDEHLTQLENNILLVQKRAMEQADIDSSWLCPDEENYTITEPEYRGSQNSSPDNPFTKSNIDYFDFVDV------EGDMETDMDRNSKKKDVLEEDLQFSSEDEFDEVPFVTDDHSEQNEAETLELSEVREGVVLADDDSQQAAEAMVQLGNVGFYMGEQQLLQQDESMDVDPNYDPSDFL 1806          

Query:    3 NLTGFMFGNVDSSGNLDGD----SVLGGLCGTSDVMRGLSSLLSTKELLKDVLSVKEEE--------------GDLCEGEVVKAEDATDYGDIEEALSDE-DSSSSEGGSENENEAEEEKGPAFGEEEGVDKETSAERTLDKILLDRSLMPPPSMDKTRGDKSRRPLAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFGI-KASHRPRIWKGVKKRRKKK---DIDNIEEQGSKIKKLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAGD-DSNGKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSK----TAIPGIKLQTMQQKRPING--------------------DDTWYSIFPVENEELVYGRWEDEVIWDDGRMPRL-HPKIVSLDPNDDNIILGIPEDIDPSTLPSDE-PIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQES---LKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKP-VNKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFSIGN-KILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEKLGLKGNKKLS----------------SKALAKAKKDLKLVCGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQHADKLRRETVKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQTDIDSLGAA-----LGVEEPPKKKRGRPRKKGP----KIVSAEFIDVGSEEAPGGSMEARHSEEAEGSGLLEEDLQYSSEEDWEEV-------VEEDNSSSFTVT-----VDPLDQQTPHAEDQVDPLVTMNFYXDNQATAGGEEELEVDENYDPSAFLHNLGKQLPTEIKEEDEYIPPPVAAQSAEDENDFGNSTYKEEPVDIKDDLDISDSDDNDED 1823
            N+TGF+FGN+D +G L+ D         L   S +  GLSS ++  E++ +  + +E E               D+    + K+  A D+ DI E   D  D  S   G + + + E     A  +EE V K  +       I  ++  +     +  R  K   PLA+MLP K+  ++V ELFP+FR NKVLRFSRLFG  K S  P+IW+GV+KRRKKK   DI + +    +  K      W   Y   P   EA   D   K  RP  D +  GK G    NG       GPK  DWR GPA+ WYD+L +P   D F Y         E+ + K E KD+                            D  DDAF MV+Q++WE+DVVWNGDDIKHKV+QKLNSK NAAGWVPS+ NRTA +FSQ  K    T  P ++L T Q   P++                     DDTWYSIFPVENEELVYG WE+EVIWD  +M ++  PKI++LDPND+NI+LGIP+DIDP+ L  D  P  KVKI   HVK+S++LL ++G+I+V+EE++PPPPPK  D DPFNISND YY PK+ E+   LKV  G  L+QH+TPVVEL+ PFV TH+GP++LR FHRPP++RFS GPL    A +GV+PL KHIKKKAK RE ER  +GGG++FFMRTPED++G+DGELVL EF EEH PL++ VGMCSK+KNYYKR+   D+GP  +KYGE+  AHTSPFLG ++PGQS+QA+ENNM+R+P++EH  P +DF++IR+R ++ +RE+D LFV GQECPLYEVPGPNSKRANNF RDFLQVFIYRLFWKSRD P+RIKMD+IKKAFP+HSESSIRKRLK CA+F RTG DSNWWVIK +FRLPTEEEIR+MV PE CCAYFSMIAAEQRL+DAGYGEKFLF  QD+DDED  LKMDDE+KVAPWNTTRAYI AMKGKCLLQL GPADPTG  GEGFSYVR+PNKP ++KEEQE QPKRTVTGTDADLR+L L +A+A+LR  GVPE+EI  LSRW+VIDVVRTLSTEK KAGE+G  KFSRGNRFSIAEHQERY+++CQR+F +QNRVL S+EVLS+DE ESSEE+         EMGKN+ENMLSNKKTS+Q   EREE +R  L+KM+MGE     E+   KG    KKDE ++S  NNF+    ++LKI RTF+  +GKE+TR ELVRKP VI+TYIK+R +KDE FI+QFAT+D+ QKEEMK+E+RRIQEQLRRIKRN+E+E++ L G+  ++                +     +  +LKL CGACG  GHMRTNK CP +        + +VAMTE+ EE++EKQL  N ++++LVNVDGTKVKLS+K+++HA++++R T+ LK+PK+AV    +KKR +  T +HCDYL   + RP  RRRTDP++  +T LE I N++R + +   FL PVN K +P Y  +I+ PMDLQTIREN++ KKY  REEFL+DVNQIV NS ++NG +   T  AK+++D  + +L E ED+LM+LEKAINPLLDDNDQVALT+ILDN++N K+KSM E WPFMKPVNKK  K YY IVK PMDLET+S KV+ ++YHSRHEFL DIE I  N   YNG+ S  T+K   ++ V + TL+EY +HLT LE  I  VQ+ A+EQ DIDS           + EP  +         P     +   +F+DV       G MEA     ++   +LEEDLQ+SSE++++EV        E++ + +  ++     V   D  +  A + +  L  + FY   Q     +E ++VD NYDPS FL                     +A   A D  D G +        I+DDL +S+SDD+ E+
Sbjct:   17 NITGFLFGNIDDNGQLEDDILDPDAKQHLASLSRL--GLSSFIN--EMMSNDNNAEERETGKVDEKKDQNTTTNDMDVDYLAKSPTALDFSDINELAEDTIDEISKSNGFDRKLDKENADYDA-DDEEVVSKSDTQLMPPPPIPEEKETLTAEEAEAARQRKLETPLASMLPSKYANINVTELFPDFRTNKVLRFSRLFGPGKPSSLPQIWRGVRKRRKKKKHHDIRDSDSGSDQDDKKSKFKGWIMQYGPEPS-TEACRSDDENKLLRPVEDKEQTGKTGESGENGD-----MGPKVADWRFGPAQLWYDMLEVPETGDGFNY-GFKMVEKAEEQENKPETKDE----------------------------DFTDDAFLMVSQLHWEDDVVWNGDDIKHKVMQKLNSKNNAAGWVPSSGNRTAQAFSQPGKGASVTVTPNVRLATSQITTPLHMQSQKNKMNMGKGNQQPQREEDDTWYSIFPVENEELVYGLWEEEVIWDPEQMKKIPKPKILTLDPNDENIVLGIPDDIDPALLHKDNGPQPKVKIPHPHVKKSKLLLGKAGVINVLEEDTPPPPPKSPDRDPFNISNDTYYMPKSSETTLRLKVGGG-NLIQHSTPVVELRVPFVQTHMGPMRLRNFHRPPLRRFSYGPLA-LPAPHGVLPLLKHIKKKAKQREQERIASGGGDVFFMRTPEDLTGRDGELVLVEFSEEHPPLMNQVGMCSKVKNYYKRRAGKDQGPQTYKYGETAYAHTSPFLGILTPGQSIQAIENNMYRAPLYEHKIPETDFLVIRSRQQYFVREMDALFVAGQECPLYEVPGPNSKRANNFVRDFLQVFIYRLFWKSRDTPRRIKMDDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVIKPDFRLPTEEEIRAMVSPEQCCAYFSMIAAEQRLKDAGYGEKFLFTPQDDDDEDMQLKMDDEVKVAPWNTTRAYIQAMKGKCLLQLAGPADPTG-CGEGFSYVRVPNKPTISKEEQEAQPKRTVTGTDADLRRLSLNNAKALLRKFGVPEEEIKKLSRWEVIDVVRTLSTEKAKAGEEGMTKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLSSNEVLSTDEGESSEEDSSDI----EEMGKNIENMLSNKKTSTQLSLEREEQQRHELRKMLMGEAQ---EQESKKGKESKKKDEEEDSPVNNFNAQQGRVLKIYRTFRNPEGKEYTRVELVRKPAVIDTYIKIRNSKDETFIKQFATLDEAQKEEMKREKRRIQEQLRRIKRNQERERM-LGGSSIVNGSNINNSSNIFDRNNINTPTTTSSTNLKLKCGACGNVGHMRTNKACPLYQNSIATAPV-NVAMTEEQEEEIEKQL--NTDDQDLVNVDGTKVKLSSKLIKHAEEVKRRTLLLKVPKEAV---NSKKRRKPPTDDHCDYLKR-HQRPVNRRRTDPVVVMSTMLESILNEMRDLPDVQPFLFPVNAKVVPDYHKIIQRPMDLQTIRENLRLKKYQSREEFLADVNQIVENSTLYNGAKSSLTVAAKRMLDTCVERLGEKEDRLMRLEKAINPLLDDNDQVALTFILDNVVNNKLKSMTEVWPFMKPVNKKMVKDYYNIVKKPMDLETVSKKVSAHKYHSRHEFLRDIEQILENCSIYNGKESPLTSKAELLVKVCKDTLDEYDEHLTQLENNILLVQKRAMEQADIDSSWLCPDEENYTITEPEYRGSQNSSPDNPYSKQNMDDFDFVDV------EGDMEADMDRNSKKKDVLEEDLQFSSEDEFDEVPFGTDDHSEQNEAETLELSEVREGVVLADDDSQQAAEAMVQLGNVGFYMGEQQLLQQDESMDVDPNYDPSDFL---------------------LAGLPARD--DKGENK-------IQDDLAVSESDDDTEN 1835          

Query:    3 NLTGFMFGNVDSSGNLDGD----SVLGGLCGTSDVMRGLSSLLSTKELLKDVLSVKEEE---------------GDLCEGEVVKAEDATDYGDIEEALSDE-DSSSSEGGSENENEAEEEKGPAFGEEEGVDKETSAERTLDKILLDRSLMPPPSMDKTRGDKSRRPLAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFGI-KASHRPRIWKGVKKRRKKK---DIDNIEEQGSKIKKLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAGD-DSNGKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSK----TAIPGIKLQTMQQKRPING--------------------DDTWYSIFPVENEELVYGRWEDEVIWDDGRMPRL-HPKIVSLDPNDDNIILGIPEDIDPSTLPSDE-PIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQES---LKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKP-VNKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFSIGN-KILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEKLGLKGNKKLS--SKALAKAKKDLKLVCGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQHADKLRRETVKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQTDIDSLGAA-----LGVEEPPKKKRGRPRKKGP----KIVSAEFIDVGSEEAPGGSMEARHSEEAEGSGLLEEDLQYSSEEDWEEV--VEEDNS----------SSFTVTVDPLDQQTPHAEDQVDPLVTMNFYXDNQATAGGEEELEVDENYDPSAFL 1763
            N+TGF+FGN+D +G L+ D         L   S +  GLSS ++  E++ +  + +E E                D+    +VK+  A D+ DI E   D  D  S   G + + + E     A  +EE V K  +       I  ++  +     +  R  K   PLA+MLP K+  +DV ELFP+FRANKVLRFSRLFG  K S  P+IW+GV+KRRKKK   D+ + +    +  K      W   Y   P   EA   D   K  RP  D +  GK G    NG       GPK  DWR GPA+ WYD+L +P   D F Y         E+ + K E KD+                            D  DDAF MV+Q++WE+DVVWNGDDIKHKV+QKLNSK NAAGWVPS+ NRTA +FSQ  K    T  P ++L T Q   P++                     DDTWYSIFPVENEELVYG WE+EVIWD   M ++  PKI++LDPND+NI+LGIP+DIDP+ L  D  P  KVKI   HVK+S++LL ++G+I+V+EE++PPPPPK  D DPFNISND YY PK+ E+   LKV  G  L+QH+TPVVEL+ PFV TH+GP++LR FHRPP++RFS GPL    A +GV+PL KHIKKKAK RE ER  +GGG++FFMRTPED++G+DGELVL EF EEH PL++ VGMCSK+KNYYKR+   D+GP  +KYGE+  AHTSPFLG ++PGQS+QA+ENNM+R+P++EH  P +DF++IR+R ++ IRE+D LFV GQECPLYEVPGPNSKRANNF RDFLQVFIYRLFW S D P+RI+MD+IKKAFP+HSESSIRKRLK CA+F RTG DSNWWVIK +FRLPTEEEIR+MV PE CCAYFSMIAAEQRL+DAGYGEKFLF  QD+DDED  LKMDDE+KVAPWNTTRAYI AMKGKCLLQL GPADPTG  GEGFSYVR+PNKP ++KEEQE QPKRTVTGTDADLR+L L +A+A+LR  GVPE+EI  LSRW+VIDVVRTLSTEK KAGE+G  KFSRGNRFSIAEHQERY+++CQR+F +QNRVL S+EVLS+DE ESSEE+         EMGKN+ENMLSNKKTS+Q   EREE +R  L+KM+MGE     E+   KG    KKDE ++S  NNF+    ++LKI RTF+  +GKE+TR ELVRKP VI+TYIK+R +KDE FI+QFAT+D+ QKEEMK+E+RRIQEQLRRIKRN+E+E++    + ++S   +   K K DLKL CGACG  GHMRTNK CP +        + +VAMTE+ EE++EKQL  N ++++LVNVDGTKVKLS+K+++HA++++R T+ LK+PK+AV    +KKR +  T +HCDYL   + RP  RRRTDP++  +T LE I N++R + +   FL PVN K +P Y  +I+ PMDLQTIREN++ KKY  REEFL+DVNQIV NS ++NG +   T  AK+++D  + +L E ED+LM+LEKAINPLLDDNDQVALT+ILDN++N K+KSM E WPFMKPVNKK  K YY IVK PMDLET+S KV+ ++YHSR EFL DIE I  N   YNG+ S  T+K   ++ V + TL+EY +HLT LE  I  VQ+ A+EQ DIDS           + EP  +         P     I   +F+DV       G ME      ++   +LEEDLQ+SSE++++EV  V +D+S          S     V   D  +  A + +  L  + FY   Q     +E ++VD NYDPS FL
Sbjct:   17 NITGFLFGNIDDNGQLEDDILDPDAKQHLASLSRL--GLSSFIN--EMMSNDNNAEERETGKVNEKKEDQNTTTNDMDVDYLVKSPTALDFSDINELAEDTIDEISKSNGFDRKLDKENADYDA-DDEEVVSKSDTQLMPPPPIPEEKETLTAEEAEAARQRKLETPLASMLPSKYANIDVTELFPDFRANKVLRFSRLFGPGKPSSLPQIWRGVRKRRKKKKHHDVRDSDSGSDQDDKKSKFKGWIMQYGPEPS-AEACRSDDENKLLRPVEDKEQTGKMGESGENGD-----MGPKVADWRFGPAQLWYDMLEVPETGDGFNY-GFKMVEKAEEQENKLETKDE----------------------------DFTDDAFLMVSQLHWEDDVVWNGDDIKHKVMQKLNSKNNAAGWVPSSGNRTAQAFSQPGKGASVTVTPNVRLATSQITTPLHMQSQKNKMNMGKGNQQPQREEDDTWYSIFPVENEELVYGLWEEEVIWDPEHMKKIPKPKILTLDPNDENIVLGIPDDIDPALLHKDNGPQPKVKIPHPHVKKSKLLLGKAGVINVLEEDTPPPPPKSPDRDPFNISNDTYYMPKSSETTLRLKVGGG-NLIQHSTPVVELRVPFVQTHMGPMRLRNFHRPPLRRFSYGPLA-LPAPHGVLPLLKHIKKKAKQREQERIASGGGDVFFMRTPEDLTGRDGELVLLEFSEEHPPLMNQVGMCSKVKNYYKRRAGKDQGPQTYKYGETAYAHTSPFLGILTPGQSIQAIENNMYRAPLYEHKIPETDFLVIRSRQQYYIREIDALFVAGQECPLYEVPGPNSKRANNFVRDFLQVFIYRLFWNSTDTPRRIRMDDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVIKPDFRLPTEEEIRAMVSPEQCCAYFSMIAAEQRLKDAGYGEKFLFTPQDDDDEDMQLKMDDEVKVAPWNTTRAYIQAMKGKCLLQLAGPADPTG-CGEGFSYVRVPNKPTISKEEQEAQPKRTVTGTDADLRRLSLNNAKALLRKFGVPEEEIKKLSRWEVIDVVRTLSTEKAKAGEEGMTKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLSSNEVLSTDEGESSEEDSSDI----EEMGKNIENMLSNKKTSTQLSLEREEQQRHELRKMLMGEAQ---EQESKKGKENKKKDEEEDSPVNNFNAQQGRVLKIYRTFRNSEGKEYTRVELVRKPAVIDTYIKIRNSKDETFIKQFATLDEAQKEEMKREKRRIQEQLRRIKRNQERERMLGGSSIEISPPKRKKPKLKPDLKLKCGACGNVGHMRTNKACPLYQNSIATAPV-NVAMTEEQEEEIEKQL--NTDDQDLVNVDGTKVKLSSKLIKHAEEVKRRTLLLKVPKEAV---NSKKRRKPPTDDHCDYLKR-HQRPVNRRRTDPVVVMSTMLESILNEMRDLPDVQPFLFPVNAKVVPDYHKIIQRPMDLQTIRENLRLKKYQSREEFLADVNQIVENSTLYNGAKSSLTVAAKRMLDTCVERLGEKEDRLMRLEKAINPLLDDNDQVALTFILDNVVNNKLKSMTEVWPFMKPVNKKMVKDYYNIVKKPMDLETVSKKVSAHKYHSRQEFLRDIEQILENCSIYNGKESPLTSKAELLVKVCKDTLDEYDEHLTQLENNILLVQKRAMEQADIDSSWLCPDEENYTITEPEYRGSQNSSPDNPFTKSNIDYFDFVDV------EGDMETDMDRNSKKKDVLEEDLQFSSEDEFDEVPFVTDDHSEQNEAETLELSEVREGVVLADDDSQQAAEAMVQLGNVGFYMGEQQLLQQDESMDVDPNYDPSDFL 1793          

Query:    3 NLTGFMFGNVDSSGNLDGD----SVLGGLCGTSDVMRGLSSLLSTKELLKDVLSVKEEEGDLCEGE------------VVKAEDATDYGDIEEALSDE-DSSSSEGGSENENEAEEEKGPAFGEEEGVDKETSAERTLDKILLDRSLMPPPSMDKTRGDKSRRPLAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFGI-KASHRPRIWKGVKKRRKKK---DIDNIEEQGSKIKKLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAGD-DSNGKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSKTAIPGIKLQTMQQKRPINGDDTWYSIFPVENEELVYGRWEDEVIWDDGRMPRL-HPKIVSLDPNDDNIILGIPEDIDPSTLPSDE-PIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQES---LKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKP-VNKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNFSIGN-KILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEKLGLKGNKKLSSKALAKAKKDLKLVCGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQHADKLRRETVKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQTDIDSLGAA-----LGVEEPPKKKRGRPRKKGP----KIVSAEFIDVGSEEAPGGSMEARHSEEAEGSGLLEEDLQYSSEEDWEEV-------VEEDNSSSFTVT-----VDPLDQQTPHAEDQVDPLVTMNFYXDNQATAGGEEELEVDENYDPSAFLHNLGKQLPTEIKEEDEYIPPPVAAQSAEDENDFGNSTYKEEPVDIKDDLDISDSDDNDEDA 1824
            N+TGF+FGN+D +G L+ D         L   S +  GLSS ++  E++ +  + +E E ++ E +            + K+  A D+ DI E   D  D  S   G + + + E     A  +EE V K  +       I  ++  +     +  R  K   PLA+MLP K+  +DV ELFP+FR NKVLRFSRLFG  K S  P+IW+GV+KRRKKK   DI + +    +  K      W   Y   P + E+   D   K  RP  D +  GK G    NG       GPK  DWR GPA+ WYD+L +P   D F Y        +E+ + K E KD+                            D  DDAF MV+Q++WE+DVVWNGDDIKHKV+QKLNSK NAAGWVPS+ NRTA +FS+ ++           Q +R    DDTWYSIFPVENEELVYG WE+EVIWD  +M ++  PKI++LDPND+NI+LGIP+DIDP+ L  D  P  KVKI   HVK+S++LL ++G+I+V+EE++PPPPPK  D DPFNISND YY PK+ E+   LKV  G  L+QH+TPVVEL+ PFV TH+GP++LR FHRPP++RFS GPL    A +GV+PL KHIKKKAK RE ER  +GGG++FFMRTPED++G+DGELVL EF EEH PL++ VGMCSK+KNYYKR+   D+GP  +KYGE+  AHTSPFLG ++PGQS+QA+ENNM+R+P++EH  P +DF++IR+R ++ +RE+D LFV GQECPLYEVPGPNSKRANNF RDFLQVFIYRLFWKS D P+RIKMD+IKKAFP+HSESSIRKRLK CA+F RTG DSNWWVIK +FRLPTEEEIR+MV PE CCAYFSMIAAEQRL+DAGYGEKFLF  QD+DDED  LKMDDE+KVAPWNTTRAYI AMKGKCLLQL GPADPTG  GEGFSYVR+PNKP ++KEEQE QPKRTVTGTDADLR+L L +A+A+LR  GVPE+EI  LSRW+VIDVVRTLSTEK KAGE+G  KFSRGNRFSIAEHQERY+++CQR+F +QNRVL S+EVLS+DE ESSEE+         EMGKN+ENMLSNKKTS+Q   EREE +R  L+KM+MGE  E   +   KG    KKDE ++S  NNF+    ++LKI RTF+  +GKE+TR ELVRKP VI+TYIK+R +KDE FI+QFAT+D+ QKEEMK+E+RRIQEQLRRIKRN+E+E++   G   + + +      +LKL CGACG  GHMRTNK CP +        + +VAMTE+ EE++EKQL  N ++++LVNVDGTKVKLS+K+++HA++++R T+ LK+PK+AV    +KKR +  T +HCDYL   + RP  RRRTDP++  +T LE I N++R + +   FL PVN K +P Y  +I+ PMDLQTIREN++ KKY  REEFL+DVNQIV NS ++NG +   T  AK+++D  + +L E ED+LM+LEKAINPLLDDNDQVALT+ILDN++N K+KSM E WPFMKPVNKK  K YY IVK PMDLET+S KV+ ++YHSRHEFL DIE I  N   YNG+ S  T+K   ++ V + TL+EY +HLT LE  I  VQ+ A+EQ DIDS           + EP  +       + P     +   +F+DV       G ME       +   +LEEDLQ+SSE++++EV        E++ + +  ++     V   D  +  A + +  L  + FY   Q     +E ++VD NYDPS FL                     +A   A D  D G +        I+DDL +S+SDD+ E+ 
Sbjct:   17 NITGFLFGNIDDNGQLEDDILDPDAKQHLASLSRL--GLSSFIN--EMMSNDNNAEERETEVDEKDQNTITNDMDVDYLAKSPTALDFSDINELAEDTIDEISKSNGFDRKLDKESADYDA-DDEEVVSKSDTQLMPPPPIPEEKETLTAEEAEAARQRKLETPLASMLPSKYANIDVTELFPDFRTNKVLRFSRLFGPGKPSSLPQIWRGVRKRRKKKKHHDIRDSDSGSDQDDKKSKFKGWIMQYGPEP-NAESCRSDDENKLLRPVEDKEQTGKTGESGENGD-----MGPKVADWRFGPAQLWYDMLEVPETGDGFNY-GFKMVEKVEEQENKSETKDE----------------------------DFADDAFLMVSQLHWEDDVVWNGDDIKHKVMQKLNSKNNAAGWVPSSGNRTAQAFSKGNQ-----------QPQR--EEDDTWYSIFPVENEELVYGLWEEEVIWDPEQMKKIPKPKILTLDPNDENIVLGIPDDIDPALLHKDNGPQPKVKIPHPHVKKSKLLLGKAGVINVLEEDTPPPPPKSPDRDPFNISNDTYYMPKSSETTLRLKVGGG-NLIQHSTPVVELRVPFVQTHMGPMRLRNFHRPPLRRFSYGPLA-LPAPHGVLPLLKHIKKKAKQREQERIASGGGDVFFMRTPEDLTGRDGELVLVEFSEEHPPLMNQVGMCSKVKNYYKRRAGKDQGPQTYKYGETAYAHTSPFLGILTPGQSIQAIENNMYRAPLYEHKIPETDFLVIRSRQQYFVREMDALFVAGQECPLYEVPGPNSKRANNFVRDFLQVFIYRLFWKSPDTPRRIKMDDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVIKPDFRLPTEEEIRAMVSPEQCCAYFSMIAAEQRLKDAGYGEKFLFTPQDDDDEDMQLKMDDEVKVAPWNTTRAYIQAMKGKCLLQLAGPADPTG-CGEGFSYVRVPNKPTISKEEQEAQPKRTVTGTDADLRRLSLNNAKALLRKFGVPEEEIKKLSRWEVIDVVRTLSTEKAKAGEEGMTKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLSSNEVLSTDEGESSEEDSSDI----EEMGKNIENMLSNKKTSTQLSLEREEQQRHELRKMLMGEAQE---QESKKGKESKKKDEEEDSPVNNFNAQQGRVLKIYRTFRNPEGKEYTRVELVRKPAVIDTYIKIRNSKDETFIKQFATLDEAQKEEMKREKRRIQEQLRRIKRNQERERM--LGGSSIVNGSSINNSSNLKLKCGACGNVGHMRTNKACPLYQNSIATAPV-NVAMTEEQEEEIEKQL--NTDDQDLVNVDGTKVKLSSKLIKHAEEVKRRTLLLKVPKEAV---NSKKRRKPPTDDHCDYLKR-HQRPVNRRRTDPVVVMSTMLESILNEMRDLPDVQPFLFPVNAKVVPDYHKIIQRPMDLQTIRENLRLKKYQSREEFLADVNQIVENSTLYNGAKSSLTVAAKRMLDTCVERLGEKEDRLMRLEKAINPLLDDNDQVALTFILDNVVNNKLKSMTEVWPFMKPVNKKMVKDYYNIVKKPMDLETVSKKVSAHKYHSRHEFLRDIEQILENCSIYNGKESPLTSKAELLVKVCKDTLDEYDEHLTQLENNILLVQKRAMEQADIDSSWLCPDEENYTITEPEYRGSQNSSPENPFSKSNMDDFDFVDVE------GDMETDIDRNLKKKDVLEEDLQFSSEDEFDEVPFGTDDHSEQNEAETLELSEVREGVVLADDDSQQAAEAMVQLGNVGFYMGEQQLLQQDESMDVDPNYDPSDFL---------------------LAGLPARD--DKGENK-------IQDDLAVSESDDDTENV 1780          

Query:    3 NLTGFMFGNVDSSGNLDGDSVLGGLCG---TSDVMRGLSSLLSTKELLKDVLSVK--------EEEGDLCE----GEVVKAEDATDYGDIEEALSDEDSSSS-----EGGSENENEAEEEKGPAFGEEEGVDKETSAERTLDKILLDRSLMPPPSMDKTRGDKSRRPLAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFGI-KASHRPRIWKGVKKRRKK------KDIDNIEEQGSKIKKLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAGDDSN-GKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEV--KDKREEETEENSKEKDIVTSEPSEEEEGSTLDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSKTA----IPGIKLQT----------------------MQQKRPINGDDTWYSIFPVENEELVYGRWEDEVIWDDGRMPRL-HPKIVSLDPNDDNIILGIPEDIDPSTLPSDE-PIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQES---LKVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKP-VNKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMIMGEGSETPEKSGSKGGSKSKKDEHDESSSNNF-SIGNKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEK-LG--LKGNKKLSSKALAKAKKDLKLV--------------------------------------------CGACGGKGHMRTNKTCPKFVPEFEGISIGSVAMTEQDEEDLEKQLMENIEEEELVNVDGTKVKLSAKVLQHADKLRRETVKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQTDIDS--LGA---ALGVEEPPKKKRGRPRKKGP----KIVSAEFIDVGSEEAPGGSMEARHSEEAEGSGLLEEDLQYSSEEDWEEVV-----EEDNSSSFTVTVDPL-----------DQQTPHAEDQVDPLVTMNFYXDNQATAGGEEELEVDENYDPSAFLHNLGKQLPTEIKEEDEYIPPPVAAQSAEDENDFGNSTYKEEPVDIKDDLDISDSDDNDEDAIEGSPVNKQSTSHSNVPPPPPLEETPDDDTLWF 1857
            N+TGF+FGN+D +G L+ D +L        TS    GLSS +    L +DV   K        EEE D  +      V K+  A D+ DI E   DE   SS     EG  E EN   +       +EE + K  +       I  ++  +     +  R  K   PLA+MLP K+  +DV ELFP+FRANKVLRFSRLFG  K S  P+IW+GVKKRRKK      +D D+  +Q  K  K K    W   Y    + P+    D   K   P  D    GK G    NG       GPK  DWR GPA+ WYD+L +P   D F Y         +  D  DE+  KDK   +T E                     +  DDAF MV+Q++WE+DV+WNGDDIKHKVLQKLNSK NAAGWVPS+ NRTA +FSQ  K A       ++L T                       QQ R  N DDTWYSIFPVENEELVYG WE+EVIWD   M ++  PKI++LDPND+NI+LGIP+DIDP+ +  D  P  KVKI   HVK+S++LL ++G+I+V+EE++PPPPPK  D DPFNISND YY P++ E+   LKV  G  L+QH+TPVVEL+ PFV TH+GP++LR FHRPP+++FS GPL  +   + V+PL KHIKKKAK RE ER  +GGG++FFMRTPED++GKDGELVL EF EEH PL++ VGMCSK+KNYYKRK   D+GP K+KYGE+  AHTSPFLG ++PGQS+QA+ENNM+R+P++EH  P +DF++IRTR ++ IREVD LFV GQECPLYEVPGPNSKRANNF RDFLQVFIYRLFWKSRD P+RIKMD+IK+AFP+HSESSIRKRLK CA+F RTG DSNWWVIK +FRLPTEEEIR+MV PE CCAYFSMIAAEQRL+DAGYGEKFLF  QD+DDE+  LKMDDE+KVAPWNTTRAYI AMKGKCLLQL GPADPTG  GEGFSYVR+PNKP ++KEEQE QPKRTVTGTDADLR+L L +A+A+LR  GVPE+EI  LSRW+VIDVVRTLSTEK KAGE+G  KFSRGNRFSIAEHQERY+++CQR+F +QNRVL S+EVLS+DE ESSEE+         EMGKN+ENMLSNKKTS+Q   EREE +R  L+KM+MGE      +   K   + KKD+ ++S  NNF S   ++LKI RTF+  +GKE+TR ELVRK  VI+TYIK+R +KDE FI+QFAT+D+ QKEEMK+E+RRIQEQLRRIKRN+E+E+ LG  + GN   SS    ++  +                                                CGACG  GHMRTNK CP +        + +VAMTE+ EE++EKQL  N ++++LVNVDGTKVKLS+K+++HA++++R T+ LK+PK+AV    +KKR R    +HCDYL     RPA RRRTDP++  +T LE I N++R + +   FL PVN K +P Y+ +I+ PMDLQTIREN++ KKY  REEFL+DVNQIV NS ++NG +   T  AK++++  + +L E ED+LM+LEKAINPLLDDNDQVALT+ILDN++N K+KSM E+WPF+KPVNKK  K YY ++K PMDLETIS KV+ ++YH+RHEFL DIE I  N   YNG+ S FT K   ++ V + TL+EY +HLT LE  I  VQ+ A+EQ DIDS  LGA      + EP  +       + P     +   +F+DV  +    GS     S  ++   +LEEDLQ+SSE++++EV      + +N+   T+ ++ +           D  +  A + +  L  + FY  +Q     +E ++VD NYDPS FL                     +A   A DE              I+DDL +S+SDD+ E+  +     KQ TS    P P P E+   D  LWF
Sbjct:   17 NMTGFLFGNIDDNGQLE-DDILDPEAKQHITSLNRLGLSSFIREMMLNEDVTEEKGNESNDKIEEENDTTDEKDINYVEKSPSALDFSDINELAEDEKEESSKQDIFEGKPEKENADYDAD-----DEEIIIKSDTQLMPPPPIPEEKETLTAEEAEAARQRKLETPLASMLPSKYANVDVTELFPDFRANKVLRFSRLFGPGKPSSLPQIWRGVKKRRKKKRHHDVRDSDSGSDQEEKKSKFK---GWVMQYGT-DQTPDMCCSDDENKLLMPIEDKEQIGKTGETGENGD-----MGPKVADWRFGPAQLWYDMLQVPETGDGFNY-------GFKLIDKTDELSNKDKNIRDTNE---------------------EFSDDAFLMVSQLHWEDDVIWNGDDIKHKVLQKLNSKNNAAGWVPSSGNRTAQAFSQPGKGAPVSVTSNVRLATSQITTPLHMQSQKTKMNMNKANQQQNREENYDDTWYSIFPVENEELVYGLWEEEVIWDPENMKKIPKPKILTLDPNDENIVLGIPDDIDPALVHKDNGPQPKVKIPHPHVKKSKLLLGKAGVINVLEEDTPPPPPKSPDRDPFNISNDTYYMPRSSETTLRLKVGGG-NLIQHSTPVVELRVPFVQTHMGPMRLRNFHRPPLRKFSHGPLA-HPGPHSVLPLIKHIKKKAKQREQERIASGGGDVFFMRTPEDLTGKDGELVLIEFSEEHPPLMNQVGMCSKVKNYYKRKAGKDQGPQKYKYGETAYAHTSPFLGILTPGQSIQAVENNMYRAPIYEHKIPETDFLVIRTRQQYYIREVDALFVAGQECPLYEVPGPNSKRANNFVRDFLQVFIYRLFWKSRDTPRRIKMDDIKRAFPSHSESSIRKRLKLCADFKRTGMDSNWWVIKPDFRLPTEEEIRAMVSPEQCCAYFSMIAAEQRLKDAGYGEKFLFTPQDDDDEEMQLKMDDEVKVAPWNTTRAYIQAMKGKCLLQLAGPADPTG-CGEGFSYVRVPNKPTISKEEQEAQPKRTVTGTDADLRRLSLNNAKALLRKFGVPEEEIKKLSRWEVIDVVRTLSTEKAKAGEEGMTKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLSSNEVLSTDEGESSEEDSSDI----EEMGKNIENMLSNKKTSTQLSLEREEQQRHELRKMLMGEV-----QEQDKKTKEKKKDDEEDSPVNNFNSQQGRVLKIYRTFRNPEGKEYTRVELVRKSAVIDTYIKIRNSKDETFIKQFATLDEAQKEEMKREKRRIQEQLRRIKRNQERERMLGGPMTGNNASSSNIFDRSSNNTPTTTSSNSILPFCNSFQSTSPASKHPKPDISPSKRKKPKLKPDLKLKCGACGNVGHMRTNKACPLYQNSITTAPV-NVAMTEEQEEEIEKQL--NTDDQDLVNVDGTKVKLSSKLIKHAEEMKRRTLLLKVPKEAV---NSKKRRRATGDDHCDYLKRQQ-RPANRRRTDPVVVMSTMLESILNEMRDLPDVQPFLFPVNAKAVPDYYKIIQRPMDLQTIRENLRLKKYQSREEFLADVNQIVENSTLYNGIKSSLTVAAKRMLETCVERLGEKEDRLMRLEKAINPLLDDNDQVALTFILDNVVNNKLKSMTEAWPFLKPVNKKLVKDYYNVIKRPMDLETISKKVSAHKYHNRHEFLRDIEQILENCTVYNGKESPFTQKAELLMKVCKETLDEYDEHLTQLENNILLVQKRAMEQADIDSSWLGADEENYTIVEPEFRGSQTSSPENPFGKTNMEDFDFVDVEGDMEGDGS----RSVNSKKKDVLEEDLQFSSEDEFDEVPFGTDEQSENAEMETLELNEVREGTEGGVVLADDDSQQAAEAMVQLGNVGFYMTDQQLLQQDESMDVDPNYDPSDFL---------------------LAGLPARDEKSENK---------IQDDLAVSESDDDTENNAK----QKQKTSQ---PLPQPEEDVGGD--LWF 1901          

Query:    3 NLTGFMFGNVDSSGNLDGDSVLGG-LCGTSDVMRGLSSLLSTKELLKDVL--------SVKEEEGDLCEGEVVKAEDATDYGDIEEALSDEDSSSSEGGSENENEAEEEKGPAFGEEEGVDKETSAERTLDKILLDRSLMPPPSMDKTRGD-----------------------------------------------KSRRPLAAMLPEKFKEMDVRELFPEFRANKVLRFSRLFGIKASHRPRIWKGV---------------KKRRKKKDIDNIEEQGSKIKKLKMSHAWEFNYADFPEDPEAYEVDAAIKFHRPAGDDSNGKEGNKDGNGKETSSRKGPKSTDWRTGPAEYWYDLLXLPPVIDNFXYVSAANAASIEQDDTKDEVKDKREEETEENSKEKDIVTSEPSEEEEGST----LDVPDDAFFMVTQVNWEEDVVWNGDDIKHKVLQKLNSKTNAAGWVPSTFNRTAGSFSQTSKTAIPGIKLQTMQQKRPINGDDTWYSIFPVENEELVYGRWEDEVIWDDGRMPR-LHPKIVSLDPNDDNIILGIPEDIDPSTLPSDEPIRKVKIIQKHVKQSRMLLNRSGIISVIEEESPPPPPKIDDMDPFNISNDVYYQPKTQESL-KVSTGRTLLQHATPVVELQAPFVPTHIGPIKLRLFHRPPVKRFSKGPLMDYTAFYGVIPLQKHIKKKAKARESERELAGGGEIFFMRTPEDISGKDGELVLFEFIEEHSPLLDLVGMCSKIKNYYKRKPENDKGPGKFKYGESTIAHTSPFLGTMSPGQSVQALENNMFRSPVFEHTPPFSDFVIIRTRTEFSIREVDGLFVVGQECPLYEVPGPNSKRANNFARDFLQVFIYRLFWKSRDNPKRIKMDEIKKAFPAHSESSIRKRLKPCAEFHRTGHDSNWWVIKNNFRLPTEEEIRSMVDPEACCAYFSMIAAEQRLRDAGYGEKFLFAQQDEDDEDTALKMDDELKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKPVNKEEQEQQPKRTVTGTDADLRKLPLKDARAILRNNGVPEQEIMNLSRWQVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYRDDCQRLFVVQNRVLGSSEVLSSDEAESSEEEEDKDDEDFNEMGKNLENMLSNKKTSSQFLREREELERRSLQKMI-MGEGSE-TPEKSGSKGGSKSKKDEHDESSSNNFSIGNKILKIVRTFKTEDGKEFTRTELVRKPLVIETYIKVRETKDEQFIRQFATIDDQQKEEMKKERRRIQEQLRRIKRNEEKEKLGLKGNKKLSSKALAKAKKDLKLVCGACGGKGHMRTNKTCPKFV-PEFEGISIGSVAMTEQDEEDLEKQL--MENIEEEELVNVDGTKVKLSAKVLQHADKLRRETVKLKIPKQAVKQQQAKKRSRTGTVEHCDYLTNTNYRPAKRRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHLTNLEEKIKEVQRIALEQTDIDSLGAALGVEEPPKKKRGRPRKKGPKIVSAEFIDVGSEEAPGGSMEARHSEEAEGSGLLEEDLQYSSEEDWEEVVEEDNS---SSFTVTVDPLDQQTPHAEDQVDPLVTMNFYXDNQATAGG------------EEELEVDENYDPSAFLHNLGKQLP 1771
            +L G  FGN+DSSG L G  +L          +  L       ELL++          S  E++G      V K  +A D+  IEEALSD+  SS +  ++ E + E  + P+  +EE   +  ++  TL+ I  + +  PP   D T                                                  +  RPLA MLPEK+K +DV+ELFPEFR  +VLRFSRLF IK S  P+ WK +               + R +  ++D    +G+ +        WEF+++ FPED + YE D AI+FH+P  +    K  ++   G+E  + KGPK+TDWR GPA+YWYD+L +P  ++N+ Y        ++ D     +K   +E     S   +      S   E ST    +D PDDAF MVTQ NWEEDVVWNGDDI+HK   K NSK NAAGWVP+  NRTAGSFSQ  K  +PGIKLQT+  KRP NGDDT+YSIFPVENEEL YGRWEDEVIWD   MPR L PKIVSLDPNDDNIILGIP+DIDPSTLPSD+P RKVKIIQKHVK+SRMLLNRSGIISVIEEESPPPPPK+D+ DPFNISND YYQ K QESL KV+ G TLLQH TPVVEL APFVPTHIGPIKL+  HR P+KR+S GPL ++ AF+GV PL KHIKKKAKARE ERE AGGGEIFFMRTPED+SG+DGEL+L E+ EEH+PLL+LVGM +K+KNYYKRKP +D    K KYG+ T+AHTSPFLG M PGQ +Q  ENN++R+PV+EH  P +DFV+IRTR E+SIREVD +F  GQECPLYEVPGPNSK+ANNFARDFLQVFI+RLFWKSRDNPKRIKMDEIK+AFPAHSESSIRKRLKPCA+FHRTGHDSNWWVIK NFRLP+EEE+R+MV PE CCA+FSMIAAEQRLRDAGYGEK + AQQD+DDE+TA+KMDDE+KVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKP NKEE EQQPKRTVTGTDADLRKLPLKDAR ILR NGVPE EI  LSRW+VIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYR+DCQR+F  QNRVL S EVLSSDE ESSEEEE  DD+ F EMGKN+EN+LSNKKTSSQ  REREE+ERR L+ M+ +G GS+ TP        +K KKD  D+  SN      K L+I RTFK   GKEFTRTE+VRKPLV+ETY+++RETKD+ FI+QFAT+DD  KEEMKKE+RR+QEQLRRIKRN+E+E+LGL      +SK   KAK DLKL CGACG KGHMRTNK CPKF+  EF+G    +VAMTE+DEE+LEK++  ME   +E L+NVDGTK+ LS KVL+HAD++R++T+ LK+PKQ +K     +R R GTVEHCDYLTN NY+P KRRRTDP+++ A++LE +H +LRVMDEALQFLQPVN K++  Y D IK PMDL TIRE +QKKKYH REEFL D+ QIV NS I+NG +DIHT NAK+L+D+VI K SENE+KL KLEKAINPLLDD+DQV L+YI   +L EK+K + ESWPF+KPVN+K  K YY+ +K PMDLETIS +V K+ YHS HEFL D+ELIY+NSL++NG  S++T K  K+L+++   +  +++H+  LE++I++ Q  ALE  + +S      ++E P KK+    +K    +S+EF+   +  +P   M+    E+   +  LE+DLQYSS++D ++   +       S  VTVD   Q      D V+ +  M +Y + QA  GG            +EE +VDENYDP+ FLHNLG  +P
Sbjct:   41 SLMGLFFGNIDSSGQLTGSDILDADSTAKLAGLERLLGGGGAAELLEEADLRPGDPSDSTAEQDGQEEYDGVSKDPEAQDFEAIEEALSDDSDSSEDEDNQAEVKTEN-RAPSPLKEETAPEAKASGATLE-IKSEPADSPPSPADATPAGINESPIKTESPPELKSEEAKKLMPPPPELPIPPVKSSPDVKSQNSLRRDHRPLAGMLPEKYKNIDVQELFPEFRHGQVLRFSRLFPIKDSLLPKPWKHLKKKAKKRLQSDGPPGESRAQGDELDVGGVEGTHL----TFRGWEFDFSPFPEDSKLYEEDDAIRFHKPQEEK---KLEDEAAEGRERIN-KGPKATDWRWGPAQYWYDILGVPDNVENYDYGLKTALDHMDDDILPQGIK---QESFHYPSAPLNGSNKGGSSSGEFSTKKCKIDFPDDAFLMVTQTNWEEDVVWNGDDIRHK---KWNSKANAAGWVPTGVNRTAGSFSQPGKGGLPGIKLQTI--KRPENGDDTFYSIFPVENEELAYGRWEDEVIWDTENMPRKLKPKIVSLDPNDDNIILGIPDDIDPSTLPSDQPTRKVKIIQKHVKKSRMLLNRSGIISVIEEESPPPPPKVDNKDPFNISNDEYYQAKAQESLIKVAPGGTLLQHGTPVVELSAPFVPTHIGPIKLKQLHRWPLKRYSHGPLANFNAFHGVNPLTKHIKKKAKARELEREAAGGGEIFFMRTPEDLSGRDGELILVEYAEEHAPLLNLVGMATKVKNYYKRKPGSDAPANKPKYGDLTLAHTSPFLGQMIPGQMIQTFENNLYRTPVYEHKMPTTDFVVIRTRNEYSIREVDTIFCAGQECPLYEVPGPNSKKANNFARDFLQVFIFRLFWKSRDNPKRIKMDEIKRAFPAHSESSIRKRLKPCAQFHRTGHDSNWWVIKQNFRLPSEEEMRAMVTPEQCCAFFSMIAAEQRLRDAGYGEKSVLAQQDDDDEETAMKMDDEVKVAPWNTTRAYILAMKGKCLLQLTGPADPTGPAGEGFSYVRIPNKPTNKEEVEQQPKRTVTGTDADLRKLPLKDARNILRQNGVPEDEIKKLSRWEVIDVVRTLSTEKVKAGEDGDHKFSRGNRFSIAEHQERYREDCQRIFETQNRVLASDEVLSSDEPESSEEEEANDDDLF-EMGKNMENLLSNKKTSSQLNREREEVERRKLKMMMELGGGSDSTP--------NKRKKD--DDEHSNGSQGPTKFLRITRTFKNPSGKEFTRTEIVRKPLVVETYVRIRETKDDAFIKQFATLDDSAKEEMKKEKRRLQEQLRRIKRNQERERLGLTK----ASKRKIKAKPDLKLKCGACGAKGHMRTNKACPKFIGGEFDGPI--NVAMTERDEEELEKEIYDMEETADESLINVDGTKMTLSGKVLKHADEIRKKTMILKVPKQTLK---GGRRRRAGTVEHCDYLTNKNYKPVKRRRTDPVVSLASFLEELHGELRVMDEALQFLQPVNTKKVIDYLDKIKIPMDLATIRECVQKKKYHSREEFLGDIGQIVDNSRIYNGEQDIHTVNAKRLLDVVIMKFSENEEKLQKLEKAINPLLDDDDQVGLSYIFTQLLEEKLKVLPESWPFVKPVNRKAMKHYYDRIKQPMDLETISKRVGKHTYHSSHEFLHDVELIYTNSLEFNGHESEYTAKAKKLLEISHEFINSFAEHIMQLEDRIRDTQARALENAETES----TLMDEMPVKKKRGRPRKKKLPLSSEFVS-DNARSPTDLMD----EDDTSNVNLEQDLQYSSDDDMDDDDWDPVDVDEGSVNVTVDSSMQHQDQEVDVVN-IGNMGYYQEIQAGDGGPAVQIEGPSIVYQEEEQVDENYDPTDFLHNLGAPMP 1858          

Query: 1402 FLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSE--------------NEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDF 1586
            FL   + + LP Y++VI  P+ L  IR+ ++  +Y +  E   D+N +  N   +N PE    +   KL  ++ AKL E              +E   + ++   +P+     +  +  + + +LN K   +Q    FM+  +KK    YYEI+ +PMD+ TI++K+   QY S  + ++D++L+++N  +YN E SD 
Sbjct:  827 FLTLPSKRELPDYYEVITEPISLNQIRKKLKSSEYSQISELADDLNLMFENCKSYNRPESRLYKEGAKLQKIMNAKLEELQLEEEDDEVVGEGSEANKLVIKSPRDPI-----RKRMRVLYNTVLNHKRNGVQIISMFMEKPSKKDYPDYYEIITSPMDMNTINMKIKGGQYKSEDDMITDMKLMFTNCRRYNEEGSDI 1020          

Query: 1380 ITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSD 1606
            + + T L    N ++++     F++  + K  P Y+++I +PMD+ TI   I+  +Y   ++ ++D+  +  N   +N       ++A  L  ++++K  +      K  K  +    +  +     + D+   +  K  Q S  F+K  N K+   Y+E++KNP+D E IS K+ +  Y++  E L+D   ++ N+ +YN  +S      L +  +   T     D
Sbjct:  940 VLYNTVLNHKRNGVQIIS---MFMEKPSKKDYPDYYEIITSPMDMNTINMKIKGGQYKSEDDMITDMKLMFTNCRRYNEEGSDIYEDANVLEKVLVSKARDMGLTTSKGRKKKSYRASEKIKSLFETLRDH---KDSKGRQLSLIFLKLPNPKEFPDYFEVIKNPVDFEKISSKMKQGVYNALEECLADFVAMFDNACKYNEPDSQIYKDALTMQSLATRTCRTLQD 1160          

Query: 1408 PKRL--PSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNA---KKLMDLVIAKLSENEDKLMKLEKAINPLLDDNDQVALTYILDNILNEKIKSM-------QESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYN 1580
            PKR   P Y+DV+ +P+D+  I++ ++  +Y    E  +D ++++ N+  F   +    + A   K L+D  + KL   ED ++ L        ++++   L  +L+ +    I+         Q    F    ++K+   YY+++K+P+DL+TI  K+  N Y S  +   D+ L++ N++ +N
Sbjct:  551 PKRRTDPEYYDVVSDPIDMLRIQQKLKTDEYADMIELKADFDKLITNAHKFYADDSDEYEAASEVKDLLDRAVVKLEMGEDPVISLGNR-----EESEDSELMEMLEELFAAVIQGTDPGDGNRQIHLAFRLLPSQKRYPEYYQVIKDPLDLKTIGTKIRDNVYESLMDLEDDLSLVFKNAMHFN 730          

Query: 1507 ILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKI 1593
            +L+++LN  +K  ++ WPF +P+ K +   Y++I+K P+DL TI   + + +Y    E + DI L++ N   YN + ++    GL++
Sbjct: 1358 VLEDLLNAMMKH-KDGWPFDRPITKAEAPDYHKIIKKPIDLGTIRSSINRMKYSCNQEVVDDIRLVFQNCWTYNRDEAEEYQCGLRL 1443          

Query: 1497 DDNDQVALTYILDNILNEKIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEY 1604
            +  D   L  I+  IL   +K+ Q +WPF  PV++K    YY+ V+ PMDL TI+ ++  N Y ++  F++D + +++N   YN  ++++    + +     A L ++
Sbjct:  673 EKQDPETLYNIIKMILT-GVKNHQSAWPFQNPVDRKVVPDYYDWVQYPMDLTTITQRLKANYYCNKRLFIADSKRMFANCRAYNAPDTEYYNCAVVLEKYVNAKLRDH 779          

Query: 1386 LEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSEN 1481
            L G+ N       A  F  PV+ K +P Y+D ++ PMDL TI + ++   Y  +  F++D  ++ AN   +N P+  +   A  L   V AKL ++
Sbjct:  688 LTGVKNH----QSAWPFQNPVDRKVVPDYYDWVQYPMDLTTITQRLKANYYCNKRLFIADSKRMFANCRAYNAPDTEYYNCAVVLEKYVNAKLRDH 779          

Query: 1503 ALTYILDNILNEKIKSMQESWPFMKPVNKK--QNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDV 1596
            A   IL  I ++K      +WPF KPV+ +      Y +++K PMDL TI  K+    Y++  EF +DI LI+SN  +YN  + +      K+ DV
Sbjct:  292 ACNEILKEIFSKKHAGY--AWPFYKPVDTELLDLHDYKKVIKTPMDLGTIRNKMEGRHYNTSAEFAADIRLIFSNCFKYNPPDHEVVQMAKKLQDV 385          

Query: 1508 LDNILNEKIKSMQESWPFMKPVN--KKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYN--GENSDFTTKGLKILDVTR-ATLEEYSDHLTNL-----EEKIKE-----VQRIAL----EQTDIDSLGAALGVEEPP-KKKRGRPRKKG 1652
            L N++ + +   Q  WPF  PV+  K     Y++I+KNPMD  TI  ++  N Y S  E + D   +++N   YN  GE+     + L+ L +T+ AT+ +    L         EK+K      V+ +++     + DID L   L    PP KKK+G  RK+ 
Sbjct:   64 LKNVVMKGVWKHQFGWPFQTPVDALKLNIPDYHKIIKNPMDFGTIKKRLENNFYWSAKECIKDFNTVFTNCYVYNKAGEDIVVMAQTLEKLFLTKMATMPKEETELAATLPKPPVEKLKNKTGRPVRSMSITSSTSEMDIDGLDGPLPAALPPAKKKQGIKRKQA 228          

Query: 1399 ALQFLQPVNPKRL--PSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDL 1473
            A  F +PV+ + L    Y  VIK PMDL TIR  ++ + Y+   EF +D+  I +N   +N P+    Q AKKL D+
Sbjct:  309 AWPFYKPVDTELLDLHDYKKVIKTPMDLGTIRNKMEGRHYNTSAEFAADIRLIFSNCFKYNPPDHEVVQMAKKLQDV 385          

Query: 1402 FLQPVNPKRL---PSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMDLVIAKLSENEDKLMKLEK 1490
            F +PVN K L   P Y+ VIK PMDL ++R  I + +Y +  E L+D+NQI  N+  FN P       A K+M+ V       +DK  KLE+
Sbjct:  123 FREPVNAKALGIYPIYYQVIKRPMDLGSVRRKIDRGEYEQLGECLADINQIWTNARTFNLPGHF-VHEAAKIMEGV------TQDKWDKLEQ 207          

Query: 1515 KIKSMQESWPFMKPVNKKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDVTRATLEEYSDHL------TNLEEKIKEVQRIALEQTDIDSLGAAL 1635
            K+   Q+ + F  PV+ ++   Y E+VKNPMD + +  K+   +Y    +FL DI+LI  N+L Y   N+D   +  KI+      L++++  L      ++ EE+  E++    ++T +D  G  L
Sbjct: 1031 KLNRDQKFFMFRIPVDTEEVYDYLEVVKNPMDFDQMLNKLDNGEYFCAQDFLDDIDLIAENALAY---NTDLNYETNKIICHRAKALQDFAYALIKAEMDSDFEEECHEIKLKKTDETTVDENGDQL 1154          

Query: 1373 RRRTDPLITFATYLEGIHNQLRVMDEALQFLQPVNPKRLPSYFDVIKNPMDLQTIRENIQKKKYHKREEFLSDVNQIVANSAIFNGPEDIHTQNAKKLMD 1472
            R +  PL+ F   LE +   L+ +D    F +PV+   +P Y D IK PMD  T+   +   KY + E+  +D N IV N   +N  + I  +   KL D
Sbjct:  653 RMKLAPLLCF---LENLLTNLQAIDAHDIFSEPVSLDEVPDYLDHIKAPMDFLTMNNKLNDFKYTRVEDLETDFNLIVENCLSYNERDTIFFRAGVKLRD 749          

Query: 1507 ILDNILNEKIKSMQESWPFMKPVN--KKQNKAYYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFT 1587
             L N++ + +   Q  WPF  PVN  K     Y++IV  PMD+ T+  ++  N Y    E + D+  +++N   YN    D T
Sbjct:   89 FLKNVVIKGMWKHQHGWPFHTPVNAIKLGIPDYFKIVTRPMDMGTVKRRLENNYYWCAKEAIDDVNQMFTNCYMYNKPGEDVT 171          

Query: 1522 SWPFMKPVNKKQNKA--YYEIVKNPMDLETISLKVTKNQYHSRHEFLSDIELIYSNSLQYNGENSDFTTKGLKILDV 1596
            +WPF KPV+ +Q     Y+ I+  PMDL T+  K+    Y    EF  D+  I+ N   YN E  D      K+  V
Sbjct:  389 AWPFYKPVDAQQLGLHDYHNIITEPMDLGTVKQKMDNRDYSEPEEFAHDVRQIFKNCYTYNPETHDVVAMAKKLEQV 465