Query:    1 MSQVLNYNVGVLGHVDSGKTSLAKALSTVSSTASFDKNPQSQARGITLDLGFSSFRVRPLPAQLAGSGASELQYTLVDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGIQTQTAECLVIGEITCPKMLIVLNKVDLIDPGQRTAAVDKMKKRLKAALARTKFADAPMVAVSANPESSQEPVGVAELIEQLNAMTTMPVRNVNGPFLFSVDHCFGIRGQGTVMTGTVLQGQIHVNENVEIVTIGESRKVKSMQMFKQPVTAAQQGDRVGICVAQFDAKLLERGLVAAPGHVPWIFGAIISLKPITYFKGGIASKAKFHISLGHETVLAKITLF----EALTLEGGHARDGFNFEHDY-SYLDEIGE-DQKESVPKP--LYALLEFEKSLPVVPDCKVLGSKLDINSNSPSCRLAFHGQLLERFQDKAYVSKDLVRLKIFKEKKKEGVVERASNACEVICKSMFKKETNLSLFSGLKVLFSTGETGQIEDSFGQSGKFKVRIPDGLQASTLEQLEARSKKSKKDSSSAPTTGALDPIHISLSFKKYIFS--KKMAQ 544
            M+ +LN NVGVLGHVDSGKTSLAKALST+SSTA+FDKNPQS+ RGITLDLGFSSF V   P        S LQ+TLVDCPGHASLI+TIIGGAQI+D+MMLV+D+ KGIQTQTAECLVIGEITC  +++VLNK+D I   +R++++DKM KRL+  L  TKF DA +V VSA P  ++ P+G+++LIE L  ++ +P R+  G FLFSVDHCF IRGQGTVMTGTVLQG + +N+NVEI TI ESRKVK +QMFK+PV  A QGDR+GIC       LLERG V+ P  VP ++  I+ L  I Y+K  I +K+KFH  LGHETVL +IT+F    E  +L+     D F F   Y S  DE  E D  + +P P   Y L EFE+ + +VP  +VLG+KLD + ++  CRLAFHG+++  + DK Y++ +L +LK++K K KEG+V+R +N  EVIC++MFKKETN++ F GL+V  S+GE G+IE SFGQSGKFKV + D L  +  E L+ + KKS  DS+          I + L FK+Y+F   KKM Q
Sbjct:    1 MTGILNLNVGVLGHVDSGKTSLAKALSTISSTAAFDKNPQSKERGITLDLGFSSFSV---PNHHLNDYDS-LQFTLVDCPGHASLIRTIIGGAQILDLMMLVVDIQKGIQTQTAECLVIGEITCDTLIVVLNKIDTIASEKRSSSIDKMTKRLRLTLQNTKFKDASIVPVSAFPGENEPPLGISDLIETLKKVSFIPKRDPTGSFLFSVDHCFSIRGQGTVMTGTVLQGTVRLNDNVEISTIKESRKVKGIQMFKKPVEKASQGDRIGIC-------LLERGXVSTPKTVPIVYAVILQLNKIAYYKSDICTKSKFHFCLGHETVLGRITVFGNDKEEFSLD-----DEFRFMEKYRSPTDEASENDNSDGLPAPSKQYVLCEFERPISIVPGSQVLGTKLDTDIHANMCRLAFHGKIIVHYYDKGYLTSELPQLKVYKNKTKEGIVDRMNNDFEVICRNMFKKETNMNSFLGLEVRLSSGEKGKIESSFGQSGKFKVNLNDSLSMTAKELLDKKKKKSNNDSTL---------ISVYLDFKRYVFDPKKKMIQ 529          

Query:    6 NYNVGVLGHVDSGKTSLA---------KALSTVSSTASFDKNPQSQARGITLDLGFSSFRVRPLPAQLAGSGASELQYTLVDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGIQTQTAE-CLVIGEITCPKMLIVLNKVDLIDPGQRTAAVDKMKKRLKAALARTKFA--DAPMVAVSA--NPESSQEPVGVAELIEQLNAMTTM---PVRNVNGPFLFSVDHCFGIRGQGTVMTGTVLQGQIHVNENVEIVTIGES--RKVKSMQMFKQPVTAAQQGDRVGICVAQFDAKLLERGLVAA 286
            + N+G +GHVD GK  L          K L++    A+ D  P+ ++RGIT+++    +                  Y   DCPGHA  IK +I GA  +D  +LV+    G   QT E  L+I ++    +++ +NK D+ D       ++ ++  ++  L+   F   D P++  SA    E     +G  +++  ++A+ +    P R+++ PFL  ++H   I G+GTV+TG V +G++ V + VE +    +   KV  ++MF + +  A  GD++GI         + RG+V A
Sbjct:   37 HLNIGTIGHVDHGKXXLXXAITNXLSEKKLASYKDYAAIDNAPEERSRGITINVAHIEY------------ATENRHYAHTDCPGHADFIKNMITGANNMDGAILVVGATDGCMPQTREHLLLIKQLGVEHIVVFINKCDVAD----EEMIELVEMEVRELLSENGFPGDDIPVIKGSALSACEDKNASLGKEQIVALMSAVDSYIPNPERDLDLPFLLPIEHVHTIPGRGTVVTGRVERGKLKVGQEVEFLGFNTAIKSKVTGIEMFHKILEEANAGDQMGILAXGVKKXDVXRGMVVA 320          

Query:    1 MSQVLNYNVGVLGHVDSGKTSLAKALSTVSSTASFDKNPQSQARGITLDLGFSSFRV---------RPLPAQLAGSGASEL------------QYTLVDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGI-QTQTAECLVIGEITCPKMLIVL-NKVDLIDPGQRTAAVDKMKKRLKAALARTKFADAPMVAVSANPESSQEPVGVAELIEQLNAMTTMPVRNVNGPFLFSVDHCFGIRG-------------QGTVMTGTVLQGQIHVNENVEI 239
            +S+    N+G +GHV  GK+++ KALS V  T  F    +   R IT+ LG+++ ++         RP+     GS   +               + VDCPGH  L+ T++ GA ++D  +L+I  N+   Q QT+E L   EI   K +++L NKVDLI   Q     D++ + ++  +A      AP++ +SA  + + E   V E IE+      +P+R        S  H   IR              +G V  G++L+G + V + +E+
Sbjct:   35 ISRQATINIGTIGHVAHGKSTVVKALSGVH-TVRFKNELE---RNITIKLGYANAKIYKSSDPKCQRPVCYTSMGSNKEDTFSMNGFKYNVVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNEACPQPQTSEHLAAIEIMKLKHILILQNKVDLIKEVQAKEQQDQILRFIEGTVAE----GAPIIPISAQLKYNIEV--VCEYIEK---KIPVPLRX-----FLSEPHLIIIRSFDVNKPGSEVEDLKGGVAGGSILKGVLKVGQEIEV 291          

Query:    5 LNYNVGVLGHVDSGKTSLAKAL------------------------STVSSTASFDKNPQSQARGITLDLGFSSFRVRPLPAQLAGSGASELQYTLVDCPGHASLIKTIIGGAQIIDMMMLVI-----DVNKGIQT--QTAECLVIGEITCPKMLIV-LNKVDLIDPGQRTAAVDKMKKRLKAALARTKF--ADAPMVAVSA---------NPESSQ-------EPVGVAELIEQLNAMTTM--PVRNVNGPFLFSVDHCFGIRGQGTVMTGTVLQGQIHVNENVEIVTIGESRKVKSMQMFKQPVTAAQQGDRVGICVAQFDAKLLERGLVAA 286
            ++ N+ V GHVDSGK++    L                         +       DK    + RGIT+D+    F               +   T+ D PGH   IK +I G    D  +L+I     +   GI    QT E  ++      K LIV +NK+D  +P    A  +++KK +   + +  +  A  P V +S          +P  S           G A     L+A+ ++  P R  + P    +   + I G GTV  G V  G +     V       + +VKS++M  + +  A  GD VG  +     K ++RG VA+
Sbjct:    6 VHINIVVXGHVDSGKSTTTGHLIYQCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITIDIALWKFE------------TPKFYVTIXDAPGHRDFIKNMITGTSXADCGVLIIASGTGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQARFEEIKKEVSGYIKKVGYNPATVPFVPISGWHGDNMLQTSPNMSWYKGWEITRKEGKASGTTLLDALXSIVPPARPTDKPLRLPLQDVYKIGGIGTVPVGRVETGILKPGMVVTFAPNNLTTEVKSVEMHHESLPEATPGDNVGFNIKNVSVKDIKRGYVAS 327          

Query:    5 LNYNVGVLGHVDSGKTSLAKALS--TVSSTASF-------DKNPQSQARGITLD---LGFSSFRV---RPLPAQLAGSGASELQ---YTLVDCPGHASLIKTIIGG--AQIIDMMMLVIDVNKGIQTQTAECLVIGEITCPKMLIVLNKVDLIDPGQRTAAVDKMKKRLKA----------------ALARTKFADAPMVAVSANPESSQEPVGVAELIEQLNAMTTMPVRNVNGPFLFSVDHCFGIRGQGTVMTGTVLQGQIHVNENVEI--VTIGE--SRKVKSMQMFKQPVTAAQQGDRVGICVAQFDAKLLERGLVA-APGHVP---WIF-GAIISL-KPITYFKGGIASKAKFHISLGHETVLAKITLFEALTLEGG 340
            +   V V+G+VD+GK++L   L+   + +   F        K+ Q   R  ++    LGF S      +P    L      E      T +D  GH   +KT + G      D  ML+I  N GI   T E L +       + +V+ K+D+  P      +  + + LK+                 L+ TKF    +  +      S E + + ++   +N ++T        P  F +D  + + G GTV++GT L G I VN+N+ +    +G   S  VKS+   + PVT  + G      + +     + +G+V  AP   P   W F G I+ L  P T     IA++ +  +  G     A IT      L  G
Sbjct:  117 MEIRVAVVGNVDAGKSTLLGVLTHGELDNGRGFARQKLFRHKHEQESGRTSSVGNDILGFDSIGNVVNKPDHGNLDWVRVCEESSKVITFIDLAGHERYLKTTVFGMTGHAPDFGMLMIGANAGIVGMTKEHLGLALALSVPVFVVVTKIDMCPPNVLQDTLKLLVRILKSPGCRKFPVLVKSSDDVVLSATKFVSERLCPIFQVSNVSGENLELLKMF--MNLLSTRSPNTDKEPAEFQIDDTYSVPGVGTVVSGTNLVGTIRVNDNLLLGPDPLGNFTSIAVKSIHRKRMPVTEVRSGQTASFALKKIKRSAIRKGMVMLAPSLEPQSCWDFEGDIMVLHHPTT-----IAARYQAMVHCGSIRQTASITKMSVDCLRTG 491          

Query:    8 NVGVLGHVDSGKTSLAKALSTVSSTASF---------DKNPQSQARGITLDLGFSSFRVRPLPAQLAGSGASELQY-----TLVDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGIQTQTAECLVIGEITCPKMLIVLNKVD 135
            N+ +L HVD GKT+LA +L   +   S          D  P  QA GIT+                  S A  L +      L+D PGH      +    ++ D  +++IDV + +Q QT   L    +   K ++VLNK+D
Sbjct:   21 NICILAHVDHGKTTLADSLLACNGIISLRLSGTLRYLDSRPDEQAXGITM-----------------KSSAVSLYHENHLINLIDSPGHVDFSSEVCXAVRLSDGALVLIDVVESVQPQTRAVLKQAWVEGIKPILVLNKMD 145          

Query:    9 VGVLGHVDSGKTSLAKALSTVSSTASFDKNPQSQARGITLDLGFSSFRVRPLPAQLAGSGASELQYTLVDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGIQTQTAECLVIGEITCPKMLIVLNKVDLIDPGQRTAAVDKMKKRLK 154
            V +LGH+D GKT+L   L   S T        ++  GIT  +G  +F V P+P+ +  +       T +D PGHA+       G    D+ +LV+D  +G+  QT E L + + +    ++ +NK+D     +  A V+  K+ LK
Sbjct:  146 VAILGHIDHGKTTLLDYLRKSSVT-------DNEFGGITQHIG--AFSV-PVPSFVQNT------ITFIDTPGHAAFKSMRNRGVCATDIAILVVDACEGVLEQTLESLSMIKESGRPYIVAINKID-----KPNADVNATKESLK 270          

Query:    8 NVGVLGHVDSGKTSLAKAL--------STVSSTASFDKNPQSQARGITLDLGFSSFRVRPLPAQLAGSGASELQYTLVDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGIQTQTAECLVIGEITCPKMLIVLNKVDL 136
            N+ ++ HVD GK++LA  +         +V +    DK    + RGIT+    +S         +   G  E    L+D PGH      +    +    ++L++D N+G+Q QT             ++ VLNKVDL
Sbjct:   44 NISIIAHVDHGKSTLADRILEYVGAIDKSVDNKQVLDKLRVERERGITVKAQTASI--------IYSKGNMEYLINLIDTPGHVDFASEVTRSLKACQGVVLLVDANQGVQAQTMSNFFAAFSEDKAIIPVLNKVDL 172          

Query:    9 VGVLGHVDSGKTSLAKALSTVSSTASFDKNPQSQARGITLDLGFSSFRVRPLPAQLAG-SGASELQYTL-----VDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGIQTQTAECLVIGEITCPKMLIVLNKVDLI 137
            V VLGHVD+GKT   K L  +  T   D     +A GIT  +G ++  +  +  Q       S+ Q  L     +D PGH S       G+ + D+ +LV+D+   ++ QT E + + +      ++ LNK+D I
Sbjct:  348 VCVLGHVDTGKT---KILDKLRRTNVQD----GEAGGITQQIGATNVPIEVVQEQCKNVKDVSKTQLKLPGLLIIDTPGHESFSNLRDRGSSLCDIAILVVDIMHNLEPQTIESINLLKKKKTPFVVALNKLDRI 475          

Query:    5 LNYNVGVLGHVDSGKTSLAKALSTVSSTASFDKNPQSQARGITLDLGFSSFRVRPLPAQLAGSGASELQYTLVDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGIQTQTAECLVIGEITCPKMLIVLNKVDLIDPGQRTAAVDKMKKRLKAALARTKFADAPMVAVSANP-----ESSQEPVGVAELIEQLNAMTTMPVRNVNGPFLFSVDHCFGIRGQGTVMTGTVLQGQIHVNENVEIVTIGESRKVKSMQMFKQPVTAAQQGDRVGICVAQFDAKLLERGLVAAPGHVPWIFGAIISLKPITYFKGGIASKAKFHISLGHETVLAKITLF----EALTLEGGHARDGFNFEHDYSYLDEI-----------GEDQKES---------VPKPLYALLEFEKSLPVVPDCKVLGSKLDINSNSPSCRLAFHGQLLERFQDKAYVSKDLVRLKIFKEKKKEGVVERASNACEVICKSMFKKETNLSLFSGLKVLFSTGETGQIEDSFGQSGKFKVRIPDGLQASTLEQLEARSKK---SKKDSSSAPTTGA-----LDPIHISLSFKKYIFS--KKMAQ 544
            +N NVGVLGH+DSGKT+LA+ALST +STA+FDK PQS+ RGITLDLGFS F V PLP    GS  + LQ TLVDCPGHASLI+TIIGGAQIID+MMLVIDV KG+QTQ+AECLVIG+I C K+++VLNK+DL+  G+R AA+DKM K+++  L  TKF  AP++ V+A P       ++ P G++ELIE L +  ++P R+ +GPFL SVDHCF I+GQGTVMTGT+L G I + ++VEI  +   +KVKSMQMF  PVT+A QGDR+GICV QFD KLLERGLV AP  +  +  A+IS++ I YF+G + +KAKFHI++GHETV+ +   F    ++  LE     D F+   +Y + ++            G+D+ +           P+  +AL+EFEK +     C V+GS+LD + ++ +CRLAFHG LL+  +DK Y+   L  L+++K K K G+VER  +   VI +S+FKKETN+ LF GLKV  STGE G I+ +FGQSGKFK+ IP GL   + + L    KK   + +  ++ P  G      + P+ ++LSFK+Y+F   K+M Q
Sbjct:    6 VNVNVGVLGHIDSGKTALARALSTTASTAAFDKQPQSRERGITLDLGFSCFVV-PLPGAEPGSSDTLLQVTLVDCPGHASLIRTIIGGAQIIDLMMLVIDVTKGMQTQSAECLVIGQIACQKLVVVLNKIDLLAEGKRQAAIDKMTKKMQKTLENTKFRGAPIIPVAAKPGGPEAPETEAPQGISELIELLKSQISIPTRDPSGPFLMSVDHCFSIKGQGTVMTGTILSGTISLGDSVEIPALKVVKKVKSMQMFHTPVTSAMQGDRLGICVTQFDPKLLERGLVCAPESLHTVHAALISVEKIPYFRGPLQTKAKFHITVGHETVMGRTLFFSPAPDSFDLE--PVLDSFDLSREYLFQEQYLCKDSMPTATEGDDEADPKAGHAPGGHCPRQQWALVEFEKPVTCPRLCLVIGSRLDADIHTNTCRLAFHGVLLQGLEDKNYIESFLPALRVYKLKHKHGLVERVMDDYSVIGRSLFKKETNIQLFVGLKVQLSTGEQGIIDSAFGQSGKFKIHIPGGLSPESKKILTPTLKKRSRAGRGETTKPEEGTERPEPIQPVTLNLSFKRYVFDTQKRMVQ 581          

Query:    5 LNYNVGVLGHVDSGKTSLAKALSTVSSTASFDKNPQSQARGITLDLGFSSFRVRPLPAQLAGS--------------GASELQYTLVDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGIQTQTAECLVIGEITCPKMLIVLNKVDLIDPGQRTAAVDKMKKRLKAALARTKFADAPMVAVSANP-----ESSQEPVGVAELIEQLNAMTTMPVRNVNGPFLFSVDHCFGIRGQGTVMTGTVLQGQIHVNENVEIVTIGESRKVKSMQMFKQPVTAAQQGDRVGICVAQFDAKLLERGLVAAPGHVPWIFGAIISLKPITYFKGGIASKAKFHISLGHETVLAKITLFEAL--TLEGGHARDGFNFEHDYSYLDEI-------------------GEDQKESVPKPLYALLEFEKSLPVVPDCKVLGSKLDINSNSPSCRLAFHGQLLERFQDKAYVSKDLVRLKIFKEKKKEGVVERASNACEVICKSMFKKETNLSLFSGLKVLFSTGETGQIEDSFGQSGKFKVRIPDGLQASTLEQLEARSKK--------SKKDSSSAPTTGALDPIHISLSFKKYIFS--KKMAQ 544
            +N NVGVLGH+DSGKT+LA+ALST +STA+FDK PQS+ RGITLDLGFS F V PLPA+L  S              G   LQ TLVDCPGHASLI+TIIGGAQIID+MMLVIDV KG+QTQ+AECLVIG+I C K+++VLNK+DL+  G+R AA+DKM K+++  L  TKF  AP++ V+A P       ++ P G+ ELIE L +  ++P R+ +GPFL SVDHCF I+GQGTVMTGT+L G I + ++VEI  +   +KVKSMQMF  P+T+A QGDR+GICV QFD KLLERGLV AP  +  +  A+IS++ I YF+G + +KAKFHI++GHETV+ ++  F       +     D FNF  +Y + ++                    G+  +   P+  +AL+EFEK +     C V+GS+LD + ++ +CRLAFHG LL   +D+ Y    L RLK++K K K G+VERA +   VI +S+FKKETN+ LF GLKV  STGE G I+ +FGQSGKFK+ IP GL   + + L    KK        + +   SA  +     + +SL+FK+Y+F   K+M Q
Sbjct:    6 VNVNVGVLGHIDSGKTALARALSTTASTAAFDKQPQSRERGITLDLGFSCFSV-PLPARLRSSLPEFQAAPEAEPEPGEPLLQVTLVDCPGHASLIRTIIGGAQIIDLMMLVIDVTKGMQTQSAECLVIGQIACQKLVVVLNKIDLLPEGKRQAAIDKMTKKMQKTLENTKFRGAPIIPVAAKPGGPEAPETEAPQGIPELIELLTSQISIPTRDPSGPFLMSVDHCFSIKGQGTVMTGTILSGSISLGDSVEIPALKVVKKVKSMQMFHMPITSAMQGDRLGICVTQFDPKLLERGLVCAPESLHTVHAALISVEKIPYFRGPLQTKAKFHITVGHETVMGRLMFFSPAPDNFDQEPILDSFNFSQEYLFQEQYLSKDLTPAVTDNDEADKKAGQATEGHCPRQQWALVEFEKPVTCPRLCLVIGSRLDADIHTNTCRLAFHGILLHGLEDRNYADSFLPRLKVYKLKHKHGLVERAMDDYSVIGRSLFKKETNIQLFVGLKVHLSTGELGIIDSAFGQSGKFKIHIPGGLSPESKKILTPALKKRARAGRGEATRQEESAERSEPSQHVVLSLTFKRYVFDTHKRMVQ 594          

Query:    6 NYNVGVLGHVDSGKTSLAKALSTVSSTASFDKNPQSQARGITLDLGFSSFRVRPLPAQLAGSGASELQYTLVDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGIQTQTAECLVIGEITCPKMLIVLNKVDLIDPGQRTAAVDKMKKRLKAALARTKFADAPMVAVSANPESSQEPVGVAELIEQL-NAMTTMPV-RNVNGPFLFSVDHCFGIRGQGTVMTGTVLQGQIHVNENVEIVTIGESRKVKSMQMFKQPVTAAQQGDRVGICVAQFDAKLLERG--LVAAPGHVPWIFGAIISLKPITYFKGGIASKAKFHISLGHETVLAKITLFEALTLEGGHARDGFNFEHDYSYLDEI-GEDQKESVPKPLYALLEFEKSLPVVPDCKVLGSKLDINSNSPSCRLAFHGQLLE 412
            N NVG+ GH+D GKT LAK L+ ++ST++ DK  +SQ RGIT+DLGFSSF +               + TLVD PGH+ LI+T IG   IID  +LV+D  +G +TQT E L++ ++     ++V+NK+D+ +  +       MK+ L + +      ++ ++ +SA         G+ EL ++L N + ++ + R++N      +DH F I+G GTV+TGT+ +G++ V +N+ I+ I    KVKS+Q FKQ V+ A  GDRVG+ +   + + L RG  L +    +  +   I  +K +  FK  +A K K HI++G  TV A I  ++          +  N + +   L+EI G D         Y + + E+ + V    K+L  +LD+     + R+   G++++
Sbjct:    9 NVNVGLFGHIDHGKTQLAKQLTEIASTSALDKPKESQKRGITIDLGFSSFTL------------DRYRITLVDAPGHSELIRTAIGAGNIIDAALLVVDAKEGPKTQTGEHLLVLDLLNIPTIVVINKIDIANDEEIKRTEMFMKQILNSTI---NLKNSKIIKISAKTGE-----GIGELKKELKNLLDSLDIKRDINSYLKMPIDHAFKIKGVGTVVTGTIHKGKVEVGDNLRILPINHEVKVKSIQCFKQDVSIAYAGDRVGMALMGVEPESLFRGCILTSEDTKLKVVDKFIAKVKILELFKYNLAPKMKVHINIGLLTVPATIIPYKI---------EKINDKEEPIILEEIKGGDS-------CYCIFKLEERVVVDEGDKILIMRLDLPPT--TLRICGFGEVID 382          

Query:    6 NYNVGVLGHVDSGKTSLAKALSTVSSTAS----------FDKNPQSQARGITLDLGFSSFRVRPLPAQLAGSGASELQYTLVDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGIQTQTAECLVIGE-ITCPKMLIVLNKVDLIDPGQRTAAVDKMKKRLKAALARTKF-ADAPMVAVSA-----NPESSQEPVGVAELIEQLNAMTTMPVRNVNGPFLFSVDHCFGIRGQGTVMTGTVLQGQIHVNENVEIVTIGESRK--VKSMQMFKQPVTAAQQGDRVGICVAQFDAKLLERG-LVAAPGHV 290
            + NVG +GHVD GKT+L  A+S   S  +           D  P+ +ARGIT++        R +  + A        Y  VDCPGHA  IK +I GA  +D  +L++  + G + QT E L++ + +   K+++ LNK+DL DP          +  +   + +  F AD P++  SA     NPE  +    V EL+E ++    +P R+++ PFL +V+  F I G+GTV TG + +G I V + VEIV I E+RK  V  ++MF++ +   Q GD VG+ +   D K +ERG +++APG +
Sbjct:   12 HMNVGTIGHVDHGKTTLTAAISIYCSKLNKDAKALKYEDIDNAPEEKARGITIN-------ARHIEYETANR-----HYAHVDCPGHADYIKNMITGAAQMDAAILLVAADSGAEPQTKEHLLLAQRMGIKKIIVFLNKLDLADPELVELV----EVEVLELVEKYGFSADTPIIKGSAFGAMSNPEDPESTKCVKELLESMDNYFDLPERDIDKPFLLAVEDVFSISGRGTVATGRIERGIIKVGQEVEIVGIKETRKTTVTGVEMFQKILEQGQAGDNVGLLLRGVDKKDIERGQVLSAPGTI 300          

Query:    8 NVGVLGHVDSGKTSLAKALSTV---------SSTASFDKNPQSQARGITLDLGFSSFRVRPLPAQLAGSGASELQYTLVDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGIQTQTAECLVIG-EITCPKMLIVLNKVDLIDPGQRTAAVDKMKKRLKAALARTKFA--DAPMVAVSA------NPESSQEPVGVAELIEQLNAMTTMPVRNVNGPFLFSVDHCFGIRGQGTVMTGTVLQGQIHVNENVEIVTIGESRK--VKSMQMFKQPVTAAQQGDRVGICVAQFDAKLLERGLVAAP-----------------------GHVPWIFGAIISLKPITYFK-----GGIASKAKFHISLGHETVLAKITLFEALTLEGG 340
            N+G +GHVD GKT+L  A++TV            AS D  P+ +ARGIT++     ++              +  Y  VDCPGHA  +K +I GA  +D  +LV+    G   QT E +++  ++  PK+++ LNK+D+    +R   V  ++  +++ L+   F   +AP++A SA      +PE  +   G+ EL++ ++     P R  + PFL +V+  F I G+GTV TG V +G + +NE VEIV +  ++K  V  ++MF++ +  AQ GD  G+ +   D   +ERG V A                         H P+      + KP  YF+     GGI  K    + +  + V   +TL   + +E G
Sbjct:   14 NIGTIGHVDHGKTTLTAAIATVLAKKGLAEARDYASIDNAPEEKARGITINTSHIEYQ------------TEKRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLARQVGVPKIVVFLNKIDMFKDDEREEMVGLVEMDVRSLLSEYGFDGDNAPIIAGSALKALQGDPEYEK---GILELMDAVDTYIEEPKRETDKPFLMAVEDVFTITGRGTVATGRVERGVLQLNEEVEIVGLKPTKKTVVTGIEMFRKNLKEAQAGDNAGLLLRGIDRSEVERGQVLAKPKTIVPHTQFEATVYVLKKEEGGRHTPFFH----NYKPQFYFRTTDVTGGIEFKPGREMVVPGDNVELTVTLIAPIAIEEG 375          

Query:    6 NYNVGVLGHVDSGKTSLAKALSTVSSTAS----------FDKNPQSQARGITLDLGFSSFRVRPLPAQLAGSGASELQYTLVDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGIQTQTAECLVIGE-ITCPKMLIVLNKVDLIDPGQRTAAVDKMKKRLKAALARTKF-ADAPMVAVSA-----NPESSQEPVGVAELIEQLNAMTTMPVRNVNGPFLFSVDHCFGIRGQGTVMTGTVLQGQIHVNENVEIVTIGESRK--VKSMQMFKQPVTAAQQGDRVGICVAQFDAKLLERGLVAAPGHVPWIFGAIISLKPITYFKGGI 310
            + NVG +GHVD GKT+L  A+S   S  +           D  P+ +ARGIT++        R +  + AG     + Y  VDCPGHA  IK +I GA  +D  +L++  + G + QT E L++ + +   K+++ LNK+DL DP          +  +   + +  F  D P+V  SA     NP+  +    + EL+E ++    +P R+++ PFL +V+  F I G+GTV TG + +G I V + VEIV I E+RK  V  ++MF++ +   Q GD VG+ +   D K +ERG V A         AI ++ P   FK  I
Sbjct:   12 HMNVGTIGHVDHGKTTLTAAISIYCSKVNKDAKALKYEDIDNAPEEKARGITIN-------ARHIEYETAG-----MHYAHVDCPGHADYIKNMITGAAQMDAAVLLVAADSGAEPQTKEHLLLAQRMGINKIIVFLNKLDLADPELVELV----EVEVLELVEKYGFPGDTPIVKGSAFGAMSNPDDPEATKCIKELLETMDNYFDLPQRDIDKPFLLAVEDVFSISGRGTVATGRIERGVIKVGQEVEIVGIRETRKTTVTGVEMFQKILEQGQAGDNVGLLLRGVDKKDIERGQVIA---------AIGTITPHKKFKASI 310          

Query:    6 NYNVGVLGHVDSGKTSLAKALSTVSSTASF---------DKNPQSQARGITLDLGFSSFRVRPLPAQLAGSGASELQYTLVDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGIQTQTAECLVIG-EITCPKMLIVLNKVDLIDPGQRTAAVDKMKKRLKAALARTKFA----DAPMVAVSANPESSQEPVG---VAELIEQLNAMTTMPVRNVNGPFLFSVDHCFGIRGQGTVMTGTVLQGQIHVNENVEIVTIGESRK--VKSMQMFKQPVTAAQQGDRVGICVAQFDAKLLERGLV-AAPGHVPWIFGAIISLKPITYFK 307
            + N+G +GHVD GKT+L  A+++V S   F         DK P+ + RGIT+      ++              +  Y  +DCPGHA  IK +I GA  +D  +LV+    G   QT E +++  ++  P +++ LNKVD+ DP             ++     T++     D P++  SA      +P G   + EL++ ++     PVR+V+ PFL  V+  F I G+GTV TG + +G+I +NE VEIV I ++RK  V  ++MF++ +   Q GD  G+ +   D   LERG+V A PG          ++KP T FK
Sbjct:   12 HVNIGTIGHVDHGKTTLTAAITSVLSKKGFAESRAFGDIDKAPEERERGITISTAHVEYQ------------TEKRHYAHIDCPGHADYIKNMITGAAQMDGAILVVAGTDGPMPQTREHILLARQVNVPALVVFLNKVDIADPELLELVE------MELRELLTEYGFPGDDIPIIKGSALKALEGDPEGEKAILELMDAVDNYIPEPVRDVDKPFLMPVEDVFSISGRGTVGTGRIERGRIKINEEVEIVGIKDTRKSVVTGIEMFQKLLDEGQAGDNAGLLLRGVDKTELERGMVIAKPG----------TIKPHTKFK 305          

Query:    6 NYNVGVLGHVDSGKTSLAKALSTVSSTAS----------FDKNPQSQARGITLDLGFSSFRVRPLPAQLAGSGASELQYTLVDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGIQTQTAECLVIGE-ITCPKMLIVLNKVDLIDPGQRTAAVDKMKKRLKAALARTKF-ADAPMVAVSA-----NPESSQEPVGVAELIEQLNAMTTMPVRNVNGPFLFSVDHCFGIRGQGTVMTGTVLQGQIHVNENVEIVTIGESRK--VKSMQMFKQPVTAAQQGDRVGICVAQFDAKLLERG-LVAAPGHV 290
            + NVG +GHVD GKT+L  A+S   S  +           D  P+ +ARGIT++        R +  + A        Y  VDCPGHA  IK +I GA  +D  +L++  + G + QT E L++ + +   K+++ LNK+DL DP      V+ ++  +   + +  F A+ P++  SA     NPE  +    V EL+E ++    +P R+++ PFL +V+  F I G+GTV TG + +G I V + VEIV I E+RK  V  ++MF++ +   Q GD VG+ +   D K +ERG +++APG +
Sbjct:   12 HMNVGTIGHVDHGKTTLTAAISIYCSKLNKDAKALKYEDIDNAPEEKARGITIN-------ARHIEYETANR-----HYAHVDCPGHADYIKNMITGAAQMDAAILLVAADSGAEPQTKEHLLLAQRMGIKKIIVFLNKLDLADP----ELVELVEVEVLELVEKYGFSANTPIIKGSAFGAMSNPEDPESTKCVKELLESMDNYFDLPERDIDKPFLLAVEDVFSISGRGTVATGRIERGVIKVGQEVEIVGIKETRKTTVTGVEMFQKILEQGQAGDNVGLLLRGVDKKDIERGQVLSAPGTI 300          

Query:    8 NVGVLGHVDSGKTSLAKALSTV---------SSTASFDKNPQSQARGITLDLGFSSFRVRPLPAQLAGSGASELQYTLVDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGIQTQTAECLVIG-EITCPKMLIVLNKVDLIDPGQRTAAVDKMKKRLKAALARTKFA--DAPMVAVSANPESSQEPVGVAELIEQLNAMTTM---PVRNVNGPFLFSVDHCFGIRGQGTVMTGTVLQGQIHVNENVEIVTIGESRK---VKSMQMFKQPVTAAQQGDRVGICVAQFDAKLLERGLVAA 286
            N+G +GHVD GKT+L  A+STV            AS D  P+ +ARGIT++     +               +  Y  VDCPGHA  IK +I GA  +D  +LV+    G   QT E +++  ++  PKM++ LNK+DL++  +    VD ++  ++  L+   F   + P++  SA      +P   A+++E ++A+ +    PVR ++ PFL +V+  F I G+GTV TG V +GQ+ +NE VEIV   E  K   +  ++MF + +  A  GD  G+ +   D K +ERG V A
Sbjct:   20 NIGTIGHVDHGKTTLTAAISTVLAKKGLAEAKDYASIDAAPEEKARGITINTAHIEY------------STDKRHYAHVDCPGHADYIKNMITGAAQMDGAILVVAATDGPMPQTREHILLSKQVGVPKMVVFLNKIDLLEGEEEM--VDLVEVEIRELLSSYDFDGDNTPIIRGSARGALEGKPEWEAKVLELMDAVDSYIDSPVREMDKPFLMAVEDVFTITGRGTVATGKVERGQVKLNEEVEIVGYREEPKKTVITGIEMFNKNLQTAMAGDNAGVLLRGVDRKDIERGQVIA 302          

Query:    8 NVGVLGHVDSGKTSLAKALSTV---------SSTASFDKNPQSQARGITLDLGFSSFRVRPLPAQLAGSGASELQYTLVDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGIQTQTAECLVIG-EITCPKMLIVLNKVDLIDPGQRTAAVDKMKKRLKAALARTKFA--DAPMVAVSANPESSQEPVGVAELIEQLNAMTTM---PVRNVNGPFLFSVDHCFGIRGQGTVMTGTVLQGQIHVNENVEIVTIGESRK---VKSMQMFKQPVTAAQQGDRVGICVAQFDAKLLERGLVAA 286
            N+G +GHVD GKT+L  A+STV            AS D  P+ +ARGIT++     +               +  Y  VDCPGHA  IK +I GA  +D  +LV+    G   QT E +++  ++  PKM++ LNK+DL++  +    VD ++  ++  L+   F   + P++  SA      +P   A+++E ++A+ +    PVR ++ PFL +V+  F I G+GTV TG V +GQ+ +NE VEIV   E  K   +  ++MF + +  A  GD  G+ +   D K +ERG V A
Sbjct:   20 NIGTIGHVDHGKTTLTAAISTVLAKRGLAEAKDYASIDAAPEEKARGITINTAHIEY------------STDKRHYAHVDCPGHADYIKNMITGAAQMDGAILVVAATDGPMPQTREHILLSKQVGVPKMVVFLNKIDLLEGEEEM--VDLVEVEIRELLSSYDFDGDNTPIIRGSARGALEGKPEWEAKVLELMDAVDSYIDSPVREMDKPFLMAVEDVFTITGRGTVATGKVERGQVKLNEEVEIVGYREEPKKTVITGIEMFNKNLQTAMAGDNAGVLLRGVDRKDIERGQVIA 302          

Query:    2 SQVLNYNVGVLGHVDSGKTSLAKALSTVSSTASFDKNPQSQARGITLDLGFSSFRVRPLPAQLAGSGASE-LQYTLVDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGIQTQTAECLVIGEITCPKMLIVLNKVDLIDPGQRTAAVDKMKKRLKAALARTKFADAPMVAVSANPESSQE-----PVGVAELIEQLNAMTTMPVRNVNGPFLFSVDHCFGIRGQGTVMTGTVLQGQIHVNENVEIVTIGESRKVKSMQMFKQPVTAAQQGDRVGICVAQFDAKLLERGLVAAPGHVPWIFGAIISLKPITYFKGGIASKAKFHISLGHETVLAKITLFEALTLEGGHARDG-FNFEHDYSYLDEIGEDQKES--------VPKPLYALLEFEKSLPVVPDCKVLGSKLDINSNSPSCRLAFHGQLLERFQDKAYVSKDLVRLKIFKEKKKEGVVERASNACEVICKSMFKKETNLSLFSGLKVLFSTGETGQIEDSFGQSGKFKVRIPDGLQASTLEQLEARSKKSKKDSSSAPTTGALDPIHISLSFKKYIFS--KKMAQ 544
            S VLN NVG+LGHVDSGKTSLAKALST +STASFDKNP+SQ RGIT+DLGFSS  +  +P  L    + E LQ TLVDCPGHASLI+TIIGGAQIID+M+LV+DV KG+QTQTAECLVIGE+TC KM++VLNK DL+  G+RTA +DKM KR+K  LA + F DAP+V+V+ANP  S+      PVG+ +L E L     +P R++  PFLF+VDHCFG+RGQGTVMTGTVLQG ++VN+ VEI ++  ++KVKS+QMF++PV  A QGDR+GIC++QFD   LERG+V  PG+VP I  AIIS++ I YFKG +++KAKFHIS+GHETV+AK++ F  L      A D  F+F+ +Y + +E+  D ++         +P   +ALLEFEK +   P+C ++GSKLD + ++ +CRLAF G LLE  +DK+Y S  L RLKI+KEK K G+++RASN  EVI K+MFKKETN+ LF GL+V  STGETG IE SFGQSGK K+RIPDGL  ST E L   +K+  K +    T+   +PI I+L FK+YI+   KKM Q
Sbjct:    3 SSVLNLNVGILGHVDSGKTSLAKALSTTASTASFDKNPESQVRGITIDLGFSSLLLD-MPQHLKNLCSEEKLQLTLVDCPGHASLIRTIIGGAQIIDLMILVVDVTKGMQTQTAECLVIGEVTCQKMIVVLNKTDLLPEGKRTALIDKMTKRMKLTLANSVFKDAPVVSVAANPGGSEGVQSSLPVGLQDLTETLQKFAFVPERHILSPFLFAVDHCFGVRGQGTVMTGTVLQGAVNVNDTVEIPSVHVTKKVKSLQMFRRPVERAVQGDRIGICISQFDPNQLERGIVCMPGYVPAISSAIISVQKIKYFKGSLSTKAKFHISIGHETVMAKLSFFSLLQDSRNTANDNSFDFDKEYKFQEELLFDSQKDDTSITAKEMPVKQFALLEFEKPVLAFPNCLIIGSKLDTDIHTNTCRLAFWGHLLEGIEDKSYSSTVLPRLKIYKEKCKSGIIDRASNQYEVIGKNMFKKETNIQLFVGLQVELSTGETGIIESSFGQSGKVKIRIPDGLNESTYELLSGMTKRKGKQTQPQNTSPDPEPIKIALHFKRYIYDPKKKMVQ 561          

Query:    3 QVLNYNVGVLGHVDSGKTSLAKALSTVSSTASFDKNPQSQARGITLDLGFSSFRVRPLPAQLAGSGASELQYTLVDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGIQTQTAECLVIGEITCPKMLIVLNKVDLIDPGQRTAAVDKMKKRLKAALARTKFADAPMVAVSANP-----ESSQEPVGVAELIEQLNAMTTMPVRNVNGPFLFSVDHCFGIRGQGTVMTGTVLQGQIHVNENVEIVTIGESRKVKSMQMFKQPVTAAQQGDRVGICVAQFDAKLLERGLVAAPGHVPWIFGAIISLKPITYFKGGIASKAKFHISLGHETVLAKITLFEALTLEGGH-ARDGFNFEHDYSYLDEI--GEDQKE----------SVPKPLYALLEFEKSLPVVPDCKVLGSKLDINSNSPSCRLAFHGQLLERFQDKAYVSKDLVRLKIFKEKKKEGVVERASNACEVICKSMFKKETNLSLFSGLKVLFSTGETGQIEDSFGQSGKFKVRIPDGLQASTLEQLEARSK-KSKKDSSSAPT----TGALDPIHISLSFKKYIFS--KKMAQ 544
            + LN+N+GVLGH+DSGKTSLAKALST +STA+FDKNPQS+ RGITLDLGFSSF +   PAQLA S  S LQYTLVDCPGHASLI+TIIGGAQIID+MMLVIDV KG+QTQ+AECL+IGEITCPKM++VLNK+DL+  G+R AAV+KM KR++  L  T+F  +P++ V+A P       SQ   G+ ELIE L + T +P R+  GPFL +VDHCF IRGQGTVMTGT+L G + +N+NVEI  +  +RKVKSMQMF +PVT+A QGDRVG+CV QFD KLLERGLV +P  +  +  AIIS++ I YFKG I +KAKFHI++GHETV+ K+T F   +L  G    + F+F  +Y Y +E   G+ + E          S+P+  +ALLEFEK +    +C V+GSKLD + ++ +CRLAFHG LLE F+DK Y    L +LKIFK K+K G VER S+   VI +S+FKKETNL LF GLKV  S+GE G IE  FGQSGKFKVR+P GL   T + L   SK KSK D   A           PI I L+FK+Y+F   KKM Q
Sbjct:   10 KTLNFNIGVLGHIDSGKTSLAKALSTTASTAAFDKNPQSKERGITLDLGFSSFSLD-FPAQLA-SEHSRLQYTLVDCPGHASLIRTIIGGAQIIDLMMLVIDVTKGMQTQSAECLLIGEITCPKMVVVLNKIDLLPEGKRQAAVEKMTKRMQKTLENTRFQGSPIIPVAAKPGGPEAPESQTAQGIPELIELLKSQTYLPKRDPGGPFLMAVDHCFSIRGQGTVMTGTLLSGSLSINDNVEIPALKMTRKVKSMQMFHKPVTSAMQGDRVGVCVTQFDPKLLERGLVCSPESLRTLHAAIISVRKIPYFKGSIHTKAKFHITVGHETVMGKVTFF---SLPSGEVTENSFDFTQEYLYQEEYHSGDPKVEGKANQQVADGSLPRQQWALLEFEKPVTCPRNCLVIGSKLDTDIHANTCRLAFHGVLLEGFEDKKYPETCLPKLKIFKVKQKAGQVERVSDDYTVIGRSLFKKETNLQLFVGLKVKLSSGEAGVIEGGFGQSGKFKVRLPGGLSEETKQLLSITSKRKSKGDKGDATKEDDGKAEKQPITIILAFKRYVFDPQKKMIQ 571          

Query:    2 SQVLNYNVGVLGHVDSGKTSLAKALSTVSSTASFDKNPQSQARGITLDLGFSSFRVRPLPAQLAGSGASE-LQYTLVDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGIQTQTAECLVIGEITCPKMLIVLNKVDLIDPGQRTAAVDKMKKRLKAALARTKFADAPMVAVSANPESSQE-----PVGVAELIEQLNAMTTMPVRNVNGPFLFSVDHCFGIRGQGTVMTGTVLQGQIHVNENVEIVTIGESRKVKSMQMFKQPVTAAQQGDRVGICVAQFDAKLLERGLVAAPGHVPWIFGAIISLKPITYFKGGIASKAKFHISLGHETVLAKITLFEALTLEGGHARD-GFNFEHDYSYLDEIGED--------QKESVPKPLYALLEFEKSLPVVPDCKVLGSKLDINSNSPSCRLAFHGQLLERFQDKAYVSKDLVRLKIFKEKKKEGVVERASNACEVICKSMFKKETNLSLFSGLKVLFSTGETGQIEDSFGQSGKFKVRIPDGLQASTLEQLEARSKKSKKDSSSAPTTGALDPIHISLSFKKYIFSKK 541
            S VLN NVG+LGHVD GKT+LAKALST +STASFDKNPQSQ RGIT+DLGFSS  V  +P  L  S   E LQ TLVDCPGHASLI+TIIGGAQIID+M+LVID+ KG+QTQTAECLV+GE+TC KM++VLNK DL+  GQ+ A +DKM +++K  L  + F D+P+V+VSA P  S+      PVG+ +LIE L     +P R V+ PFLF+VDHCF +RGQGTVMTGTVLQG +++N+ VEI +I  +RKVKSMQMF++PV  + QGDR+G+CV QFD + LERG+   PG+VP I  AI+S++ I YFKG + +KAKFHIS+GHETV+AK++ F  L      + D  F+F  +Y + +E+  D        +   +P   +A+LEFEK   VVP C V+GSKLD + ++ +CRLAF G LLE  +DK Y +  L +LKI+KEK K GVV+RA N  +VI KSMFKKETN+ LF GL+V  STGETG IE SFGQSGK K+ IPDGL+ ST   L + +KK  K S    T    +PI I L F++YI+  K
Sbjct:    3 SSVLNLNVGILGHVDCGKTTLAKALSTTASTASFDKNPQSQERGITIDLGFSSLLVD-IPEHLKNSCLEEQLQLTLVDCPGHASLIRTIIGGAQIIDLMLLVIDITKGMQTQTAECLVVGEVTCQKMIVVLNKTDLLPEGQKQALIDKMTRKMKLTLQNSVFKDSPVVSVSAKPGGSEAVSASPPVGLQDLIETLQKFAFIPKRYVSSPFLFAVDHCFSVRGQGTVMTGTVLQGTVNINDTVEIPSIHVTRKVKSMQMFRKPVECSVQGDRIGLCVTQFDPRQLERGIACMPGYVPAISLAIVSVQKIKYFKGNVNTKAKFHISIGHETVMAKLSFFGLLQDFSNTSEDNAFDFNKEYKFQNELLPDPTNDDEGARAHEMPVKQFAMLEFEKPTLVVPKCLVIGSKLDSDIHAKTCRLAFWGHLLESVEDKNYSTTVLPKLKIYKEKCKCGVVDRACNQYQVIGKSMFKKETNIQLFVGLQVELSTGETGVIESSFGQSGKVKIHIPDGLKESTSVLLPSMTKKKGKHSDPQNTLPDPEPIKIVLHFRRYIYDPK 556          

Query:    1 MSQVLNYNVGVLGHVDSGKTSLAKALSTVSSTASFDKNPQSQARGITLDLGFSSFRVR-PLPAQLAGSGASELQYTLVDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGIQTQTAECLVIGEITCPKMLIVLNKVDLIDPGQRTAAVDKMKKRLKAALARTKFADAPMVAVSANPESSQEP----VGVAELIEQLNAMTTMPVRNVNGPFLFSVDHCFGIRGQGTVMTGTVLQGQIHVNENVEIVTIGESRKVKSMQMFKQPVTAAQQGDRVGICVAQFDAKLLERGLVAAPGHVPWIFGAIISLKPITYFKGGIASKAKFHISLGHETVLAKITLFEALTLEGGHARDG---------FNFEHDYSYLDEI---------------GEDQKESVPKPLYALLEFEKSLPVVPDCKVLGSKLDINSNSPSCRLAFHGQLLERFQDKAYVSKDLVRLKIFKEKKKEGVVERASNACEVICKSMFKKETNLSLFSGLKVLFSTGETGQIEDSFGQSGKFKVRIPDGLQASTLEQLE--------ARSKKSKKDSSSAPTTGALDPIHISLSFKKYIFS--KKMAQ 544
            M+ VLN+NVGVLGH+DSGKTSL KALSTV+STA+FDK+PQS+ RGITLDLGFSSF V  P   + A     +LQ+TLVDCPGHASLIKTIIGGAQIID+M+L++DV KG+QTQTAECLVIGEI C KML+VLNKVDL+   +R   VDKMK+++ A L  T+FADAP++AV+A P   + P    VG+ EL++ L   T +P R+ +GPF+F+VDHCF IRGQGTVMTGTVL G + +N+NVE+  + E +KVKSMQMFKQPV +A QGDRVG+CV QFD KLLERGLV  PG +  I  A++ ++ I +FKG   +KAKFHI++GHETV+A++  F      G  ++DG         F+F  +Y Y DE+                 +  ++VP   +ALLEFEK +     C V+GS+LD + ++ +CRLAFHGQLLE   DK Y    L +LK+FK K KEG+VER ++   VI +S+FKKETN+ LF GLKV  STGE G IE  FGQSGKFK+RIP GLQ  T++QL          ++ + +  ++  P  G    I +SL FKKYIF   KKM Q
Sbjct:    1 MAAVLNFNVGVLGHIDSGKTSLCKALSTVASTAAFDKHPQSKERGITLDLGFSSFSVDVPGHIKEADPKYEKLQFTLVDCPGHASLIKTIIGGAQIIDLMLLIVDVTKGMQTQTAECLVIGEIACQKMLVVLNKVDLLPEAKRDQMVDKMKRKMAATLKSTRFADAPIIAVAAKPGGPEAPDTEAVGLQELMDLLKKHTYLPSRDASGPFIFAVDHCFSIRGQGTVMTGTVLSGTVAINDNVEVANVKEVKKVKSMQMFKQPVNSAMQGDRVGVCVTQFDPKLLERGLVCTPGTLAVIHAAVLKVRKIRFFKGACQTKAKFHITMGHETVMARVQFF------GSPSQDGVEESSEDPHFDFTREYMYQDELYGQEGAGKGKENGTADTEAAQTVPSQQWALLEFEKPVICPQRCLVIGSRLDTDIHANTCRLAFHGQLLEPLVDKNYGETVLPKLKVFKNKSKEGMVERMTDEYTVIGRSLFKKETNIQLFVGLKVKLSTGEEGVIEGGFGQSGKFKIRIPQGLQPGTVQQLSAAGKKKKGKKADEEEAAAAQVPEKGQ-GGIQVSLQFKKYIFDTKKKMIQ 576          

Query:    2 SQVLNYNVGVLGHVDSGKTSLAKALSTVSSTASFDKNPQSQARGITLDLGFSSFRVRPLPAQLAGSGASE-LQYTLVDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGIQTQTAECLVIGEITCPKMLIVLNKVDLIDPGQRTAAVDKMKKRLKAALARTKFADAPMVAVSANPESSQE-----PVGVAELIEQLNAMTTMPVRNVNGPFLFSVDHCFGIRGQGTVMTGTVLQGQIHVNENVEIVTIGESRKVKSMQMFKQPVTAAQQGDRVGICVAQFDAKLLERGLVAAPGHVPWIFGAIISLKPITYFKGGIASKAKFHISLGHETVLAKITLFEALTLEGGHARDG-FNFEHDYSYLDEIGEDQKES--------VPKPLYALLEFEKSLPVVPDCKVLGSKLDINSNSPSCRLAFHGQLLERFQDKAYVSKDLVRLKIFKEKKKEGVVERASNACEVICKSMFKKETNLSLFSGLKVLFSTGETGQIEDSFGQSGKFKVRIPDGLQ 497
            S VLN NVG+LGHVDSGKTSLAKALST +STASFDKNP+SQ RGIT+DLGFSS  +  +P  L    + E LQ TLVDCPGHASLI+TIIGGAQIID+M+LV+DV KG+QTQTAECLVIGE+TC KM++VLNK DL+  G+RTA +DKM KR+K  LA + F DAP+V+V+ANP  S+      PVG+ +L E L     +P R++  PFLF+VDHCFG+RGQGTVMTGTVLQG ++VN+ VEI ++  ++KVKS+QMF++PV  A QGDR+GIC++QFD   LERG+V  PG+VP I  AIIS++ I YFKG +++KAKFHIS+GHETV+AK++ F  L      A D  F+F+ +Y + +E+  D ++         +P   +ALLEFEK +   P+C ++GSKLD + ++ +CRLAF G LLE  +DK+Y S  L RLKI+KEK K G+++RASN  EVI K+MFKKETN+ LF GL+V  STGETG IE SFGQSGK K+RIP   Q
Sbjct:    3 SSVLNLNVGILGHVDSGKTSLAKALSTTASTASFDKNPESQVRGITIDLGFSSLLLD-MPQHLKNLCSEEKLQLTLVDCPGHASLIRTIIGGAQIIDLMILVVDVTKGMQTQTAECLVIGEVTCQKMIVVLNKTDLLPEGKRTALIDKMTKRMKLTLANSVFKDAPVVSVAANPGGSEGVQSSLPVGLQDLTETLQKFAFVPERHILSPFLFAVDHCFGVRGQGTVMTGTVLQGAVNVNDTVEIPSVHVTKKVKSLQMFRRPVERAVQGDRIGICISQFDPNQLERGIVCMPGYVPAISSAIISVQKIKYFKGSLSTKAKFHISIGHETVMAKLSFFSLLQDSRNTANDNSFDFDKEYKFQEELLFDSQKDDTSITAKEMPVKQFALLEFEKPVLAFPNCLIIGSKLDTDIHTNTCRLAFWGHLLEGIEDKSYSSTVLPRLKIYKEKCKSGIIDRASNQYEVIGKNMFKKETNIQLFVGLQVELSTGETGIIESSFGQSGKVKIRIPGTTQ 512          

Query:    3 QVLNYNVGVLGHVDSGKTSLAKALSTVSSTASFDKNPQSQARGITLDLGFSSFRVRPLPAQLAGSGASELQYTLVDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGIQTQTAECLVIGEITCPKMLIVLNKVDLIDPGQRTAAVDKMKKRLKAALARTKFADAPMVAVSANPESSQEP-----VGVAELIEQLNAMTTMPVRNVNGPFLFSVDHCFGIRGQGTVMTGTVLQGQIHVNENVEIVTIGESRKVKSMQMFKQPVTAAQQGDRVGICVAQFDAKLLERGLVAAPGHVPWIFGAIISLKPITYFKGGIASKAKFHISLGHETVLAKITLFE--ALTLEGGHARDGFNFEHDYSYLD-EIGEDQK-------------ESVPKPLYALLEFEKSLPVVPDCKVLGSKLDINSNSPSCRLAFHGQLLERFQDKAYVSKDLVRLKIFKEKKKEGVVERASNACEVICKSMFKKETNLSLFSGLKVLFSTGETGQIEDSFGQSGKFKVRIPDGLQASTLEQLEARSKKSKKDSSSAPTTGALD------PIHISLSFKKYIFS--KKMAQ 544
            + LN+NVGVLGH+DSGKTSLAKALST +STA+FDKNPQS+ RGITLDLGFSSF V P+P  LAG+G   LQ+TLVDCPGHASLI+TIIGGAQIID+MMLVIDV KG+QTQ+AECLVIG+I C KM++VLNK+DL+   +R AA+DKM K+++  L  TKF  +P+++V+A P   + P     +GV++LIE L + T +P R+  GPFL +VDHCF I+GQGTVMTGT+L G I +N+NVEI  +  ++KVKSMQMF +PV+ A QGDR+GICV QFD KLLERGLV  P  +  I  AIIS+  I Y+KG + +KAKFHI++ HETV+AK+T F     +       + F+F  +Y Y D  I +D K             E++PK  +ALLEFEK +     C V+GSKLD + +S +CRLAFHG L+E  +DK Y    L  LK++K K KEG VER ++   +I +S+FKKETN+ LF GLKV  STGE G IE SFGQSGKFK+RIP+GLQ  T + L A SKK  K    A      +      PI I+L FK+Y+F   KKM Q
Sbjct:    6 RTLNFNVGVLGHIDSGKTSLAKALSTTASTAAFDKNPQSKERGITLDLGFSSFSV-PIPEHLAGTGYQRLQFTLVDCPGHASLIRTIIGGAQIIDLMMLVIDVTKGMQTQSAECLVIGQIACNKMVVVLNKIDLLAENKRQAAIDKMTKKMQKTLENTKFHGSPIISVAAKPGGPEAPESVTGLGVSDLIELLMSHTYLPQRDPQGPFLMAVDHCFSIKGQGTVMTGTILSGSISLNDNVEIPALKVTKKVKSMQMFHKPVSQAVQGDRLGICVTQFDPKLLERGLVCTPESLHTIHAAIISVNKIPYYKGSLQTKAKFHITVSHETVMAKVTFFSLPPASFNEELPANVFDFGKEYLYQDGYISKDSKNSEQNKVDNHQGEEAIPKQQWALLEFEKPVTCPKLCLVIGSKLDTDIHSNTCRLAFHGVLIEGVEDKNYSESFLPNLKVYKLKHKEGQVERVNDDYSIIGRSLFKKETNIQLFVGLKVKLSTGEDGVIEGSFGQSGKFKIRIPNGLQPETKKMLTASSKKRLKGKGDADPAKEEEVRQDNQPILITLWFKRYMFDPQKKMIQ 575          

Query:    2 SQVLNYNVGVLGHVDSGKTSLAKALSTVSSTASFDKNPQSQARGITLDLGFSSFRVRPLPAQLAGSGASE-LQYTLVDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGIQTQTAECLVIGEITCPKMLIVLNKVDLIDPGQRTAAVDKMKKRLKAALARTKFADAPMVAVSANPESSQE-----PVGVAELIEQLNAMTTMPVRNVNGPFLFSVDHCFGIRGQGTVMTGTVLQGQIHVNENVEIVTIGESRKVKSMQMFKQPVTAAQQGDRVGICVAQFDAKLLERGLVAAPGHVPWIFGAIISLKPITYFKGGIASKAKFHISLGHETVLAKITLFEALTLEGGHARDG-FNFEHDYSYLDEIGEDQKES--------VPKPLYALLEFEKSLPVVPDCKVLGSKLDINSNSPSCRLAFHGQLLERFQDKAYVSKDLVRLKIFKEKKKEGVVERASNACEVICKSMFKKETNLSLFSGLKVLFSTGETGQIEDSFGQSGKFKVRIP 493
            S VLN NVG+LGHVDSGKTSLAKALST +STASFDKNP+SQ RGIT+DLGFSS  +  +P  L    + E LQ TLVDCPGHASLI+TIIGGAQIID+M+LV+DV KG+QTQTAECLVIGE+TC KM++VLNK DL+  G+RTA +DKM KR+K  LA + F DAP+V+V+ANP  S+      PVG+ +L E L     +P R++  PFLF+VDHCFG+RGQGTVMTGTVLQG ++VN+ VEI ++  ++KVKS+QMF++PV  A QGDR+GIC++QFD   LERG+V  PG+VP I  AIIS++ I YFKG +++KAKFHIS+GHETV+AK++ F  L      A D  F+F+ +Y + +E+  D ++         +P   +ALLEFEK +   P+C ++GSKLD + ++ +CRLAF G LLE  +DK+Y S  L RLKI+KEK K G+++RASN  EVI K+MFKKETN+ LF GL+V  STGETG IE SFGQSGK K+RIP
Sbjct:    3 SSVLNLNVGILGHVDSGKTSLAKALSTTASTASFDKNPESQVRGITIDLGFSSLLL-DMPQHLKNLCSEEKLQLTLVDCPGHASLIRTIIGGAQIIDLMILVVDVTKGMQTQTAECLVIGEVTCQKMIVVLNKTDLLPEGKRTALIDKMTKRMKLTLANSVFKDAPVVSVAANPGGSEGVQSSLPVGLQDLTETLQKFAFVPERHILSPFLFAVDHCFGVRGQGTVMTGTVLQGAVNVNDTVEIPSVHVTKKVKSLQMFRRPVERAVQGDRIGICISQFDPNQLERGIVCMPGYVPAISSAIISVQKIKYFKGSLSTKAKFHISIGHETVMAKLSFFSLLQDSRNTANDNSFDFDKEYKFQEELLFDSQKDDTSITAKEMPVKQFALLEFEKPVLAFPNCLIIGSKLDTDIHTNTCRLAFWGHLLEGIEDKSYSSTVLPRLKIYKEKCKSGIIDRASNQYEVIGKNMFKKETNIQLFVGLQVELSTGETGIIESSFGQSGKVKIRIP 508          

Query:    5 LNYNVGVLGHVDSGKTSLAKALSTVSSTASFDKNPQSQARGITLDLGFSSFRVRPLPAQLAGSGASELQYTLVDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGIQTQTAECLVIGEITCPKMLIVLNKVDLIDPGQRTAAVDKMKKRLKAALARTKFADAPMVAVSANPESSQEP-----VGVAELIEQLNAMTTMPVRNVNGPFLFSVDHCFGIRGQGTVMTGTVLQGQIHVNENVEIVTIGESRKVKSMQMFKQPVTAAQQGDRVGICVAQFDAKLLERGLVAAPGHVPWIFGAIISLKPITYFKGGIASKAKFHISLGHETVLAKITLFE--ALTLEGGHARDGFNFEHDYSYLD-EIGEDQK-------------ESVPKPLYALLEFEKSLPVVPDCKVLGSKLDINSNSPSCRLAFHGQLLERFQDKAYVSKDLVRLKIFKEKKKEGVVERASNACEVICKSMFKKETNLSLFSGLKVLFSTGETGQIEDSFGQSGKFKVRIPDGLQASTLEQLEARSKKSK-KDSSSAPTTGAL----DPIHISLSFKKYIFS--KKMAQ 544
            LN+NVGVLGH+DSGKTSLAKALST +STA+FDKNPQS+ RGITLDLGFSSF V P+P  LAG+G   LQ+TLVDCPGHASLI+TIIGGAQIID+MMLVIDV KG+QTQ+AECLVIG+I C KM++VLNK+DL+   +R AA+DKM K+++  L  TKF  +P+V+V+A P   + P     +G+++LIE L + T +P R+ +GPFL +VDHCF I+GQGTVMTGT+L G I +N+NVEI  +  ++KVKSMQMF +PV+ A QGDR+GICV QFD KLLERGLV  P  +  I  A+IS+  I YFKG + +KAKFHI++ HETV+AK+T F     +       + F+F  +Y Y D  I +D K             E++PK  +ALLEFEK +     C V+GSKLD + +S +CRLAFHG LLE  +DK Y    L  L++FK K KEG VER ++   +I +S+FKKETN+ LF GLKV  STGE G IE SFGQSGKFK+RIP+GLQ  T + L   +KK K K    A     +     PI I+L FK+Y+F   KKM Q
Sbjct:    8 LNFNVGVLGHIDSGKTSLAKALSTTASTAAFDKNPQSKERGITLDLGFSSFSV-PVPEHLAGTGYQRLQFTLVDCPGHASLIRTIIGGAQIIDLMMLVIDVTKGMQTQSAECLVIGQIACNKMVVVLNKIDLLAENKRQAAIDKMTKKMQKTLESTKFHGSPIVSVAAKPGGPEAPESVTGLGISDLIELLKSHTYLPQRDPHGPFLMAVDHCFSIKGQGTVMTGTILSGSISLNDNVEIPALKVTKKVKSMQMFHKPVSRAMQGDRLGICVTQFDPKLLERGLVCTPESLHTIHAAVISVDKIPYFKGSLQTKAKFHITVSHETVMAKVTFFSLPPASFNEELPANAFDFGKEYLYQDGYITKDSKNSEQDKVDNHQGEEAIPKQQWALLEFEKPVTCPKLCLVIGSKLDTDIHSNTCRLAFHGVLLEGVEDKNYSESFLPNLRVFKLKHKEGQVERVNDDYSIIGRSLFKKETNIQLFVGLKVKLSTGEDGLIEGSFGQSGKFKIRIPNGLQLETKKMLVTSNKKRKGKGDVEAAKEEEIKQDSQPILITLWFKRYMFDPQKKMIQ 574          

Query:    2 SQVLNYNVGVLGHVDSGKTSLAKALSTVSSTASFDKNPQSQARGITLDLGFSSFRVRPLPAQLAGSGASE----LQYTLVDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGIQTQTAECLVIGEITCPKMLIVLNKVDLIDPGQRTAAVDKMKKRLKAALARTKFADAPMVAVSANP-----ESSQEPVGVAELIEQLNAMTTMPVRNVNGPFLFSVDHCFGIRGQGTVMTGTVLQGQIHVNENVEIVTIGESRKVKSMQMFKQPVTAAQQGDRVGICVAQFDAKLLERGLVAAPGHVPWIFGAIISLKPITYFKGGIASKAKFHISLGHETVLAKITLF-------EALTLEGGHARDGFNFEHDYSYLDEIGEDQKESV--PKP-LYALLEFEKSLPVVPDCKVLGSKLDINSNSPSCRLAFHGQLLERFQDKAYVSKDLVRLKIFKEKKKEGVVERASNACEVICKSMFKKETNLSLFSGLKVLFSTGETGQIEDSFGQSGKFKVRIPDGLQASTLEQLEARSKKSKKD-----SSSAPTTGALDPIHISLSFKKYIFS--KKMAQ 544
            ++ LN+NVGVLGHVDSGKTSLA+ALS+ +STA+FDKNPQS+ RGITLDLGFSSF V   P  L  SG  +    LQ+TLVDCPGHASLI+TIIGGAQIID+MMLV+DV KG+QTQTAECL+IGE+TCP+M++VLNK+DL+ P +R +A++KM KRL   L  T+F + P++AV+A P       ++EP GV  LIE L   T +P R+  G  L +VDHCF IRGQGTVMTGT+LQG + +N+ VEI  +  ++K+KS+QMF++PV+ A QGDRVG+CV QFD KLLERGLV  PG +  ++ AIIS + I YFKG +A++AKFHI++GHETV+AK+T F       +    E       F FE +YSY DE    QKE+   P P  +ALLEFE+ +     C V+GSKLD + ++ +CRLAF G+LL  F+DK+Y    L +L+IFK K KEG VER ++   VI +S+FKKETNL LF GLKV  STGE+G IE  FGQSGKFK+RI +GL+  T + L ++ K          S   P T +  P+ I L FK+Y+F   KKM Q
Sbjct:    9 AKTLNFNVGVLGHVDSGKTSLARALSSTASTAAFDKNPQSRERGITLDLGFSSFTVD-CPDHLRDSGGQQPYDSLQFTLVDCPGHASLIRTIIGGAQIIDLMMLVVDVVKGVQTQTAECLLIGELTCPRMVVVLNKIDLLPPNKRQSAIEKMTKRLHKTLESTRFKECPVIAVAAKPGGPEAPETEEPQGVPALIELLKQQTYLPKRDAKGDLLMAVDHCFSIRGQGTVMTGTILQGSLAINDTVEIPVLKVTKKIKSVQMFRKPVSGAMQGDRVGVCVTQFDPKLLERGLVCTPGSLRTLYAAIISTRKIGYFKGSLATRAKFHITVGHETVMAKVTFFGLPPADTKPTPSEPSSLETPFTFEREYSYQDEYVSRQKEAALGPDPEQWALLEFERPVTCPALCLVIGSKLDTDIHANACRLAFQGRLLHGFEDKSYAETSLPQLRIFKTKHKEGQVERVTDDYSVIGRSLFKKETNLQLFVGLKVTLSTGESGVIEGGFGQSGKFKIRIQEGLRPETKQLLSSKKKGKSGSKGGPASEEEPKTES-QPVGIHLHFKRYVFDPHKKMVQ 575          

Query:    5 LNYNVGVLGHVDSGKTSLAKALSTVSSTASFDKNPQSQARGITLDLGFSSFRVRPLPAQLAGSGASELQYTLVDCPGHASLIKTIIGGAQIIDMMMLVIDVNKGIQTQTAECLVIGEITCPKMLIVLNKVDLIDPGQRTAAVDKMKKRLKAALARTKFADAPMVAVSANPESSQEP-----VGVAELIEQLNAMTTMPVRNVNGPFLFSVDHCFGIRGQGTVMTGTVLQGQIHVNENVEIVTIGESRKVKSMQMFKQPVTAAQQGDRVGICVAQFDAKLLERGLVAAPGHVPWIFGAIISLKPITYFKGGIASKAKFHISLGHETVLAKITLFE--ALTLEGGHARDGFNFEHDYSYLD-EIGEDQK-------------ESVPKPLYALLEFEKSLPVVPDCKVLGSKLDINSNSPSCRLAFHGQLLERFQDKAYVSKDLVRLKIFKEKKKEGVVERASNACEVICKSMFKKETNLSLFSGLKVLFSTGETGQIEDSFGQSGKFKVRIPDGLQASTLEQLEARSKKSK-KDSSSAPTTGAL----DPIHISLSFKKYIFS--KKMAQ 544
            LN+NVGVLGH+DSGKTSLAKALST +STA+FDKNPQS+ RGITLDLGFSSF V P+P  LAG+G   LQ+TLVDCPGHASLI+TIIGGAQIID+MMLVIDV KG+QTQ+AECLVIG+I C KM++VLNK+DL+   +R AA+DKM K+++  L  TKF  +P+V+V+A P   + P     +G+++LIE L + T +P R+ +GPFL +VDHCF I+GQGTVMTGT+L G I +N+NVEI  +  ++KVKSMQMF +PV+ A QGDR+GICV QFD KLLERGLV  P  +  I  A+IS+  I YFKG + +KAKFHI++ HETV+AK+T F     +       + F+F  +Y Y D  I +D K             E++PK  +ALLEFEK +     C V+GSKLD + +S +CRLAFHG LLE  +DK Y    L  L++FK K K+G VER ++   +I +S+FKKETN+ LF GLKV  STGE G IE SFGQSGKFK+RIP+GLQ  T + L   +KK K K    A     +     PI I+L FK+Y+F   KKM Q
Sbjct:    8 LNFNVGVLGHIDSGKTSLAKALSTTASTAAFDKNPQSKERGITLDLGFSSFSV-PVPEHLAGTGYQRLQFTLVDCPGHASLIRTIIGGAQIIDLMMLVIDVTKGMQTQSAECLVIGQIACNKMVVVLNKIDLLAENKRQAAIDKMTKKMQKTLESTKFHGSPIVSVAAKPGGPEAPESVTGLGISDLIELLKSHTYLPQRDPHGPFLMAVDHCFSIKGQGTVMTGTILSGSISLNDNVEIPALKVTKKVKSMQMFHKPVSRAMQGDRLGICVTQFDPKLLERGLVCTPESLHTIHAAVISVDKIPYFKGSLQTKAKFHITVSHETVMAKVTFFSLPPASFNEELPANAFDFGKEYLYQDGYISKDSKNSEQDKVDNHQGEEAIPKQQWALLEFEKPVTCPKLCLVIGSKLDTDIHSNTCRLAFHGVLLEGVEDKNYSESFLPNLRVFKLKHKQGQVERVNDDYSIIGRSLFKKETNIQLFVGLKVKLSTGEDGLIEGSFGQSGKFKIRIPNGLQLETKKMLVTSNKKRKGKGDVEAAKEEEIKQDSQPILITLWFKRYMFDPQKKMIQ 574