discs large 1, maker-scaffold356_size197960-snap-gene-0.36 (gene) Tigriopus kingsejongensis

Overview
Namediscs large 1
Unique Namemaker-scaffold356_size197960-snap-gene-0.36
Typegene
OrganismTigriopus kingsejongensis (Tigriopus kingsejongensis)
Associated RNAi Experiments

Nothing found

Homology
BLAST of discs large 1 vs. L. salmonis genes
Match: EMLSAG00000000935 (supercontig:LSalAtl2s:LSalAtl2s1165:38108:40629:1 gene:EMLSAG00000000935 transcript:EMLSAT00000000935 description:"maker-LSalAtl2s1165-augustus-gene-0.25")

HSP 1 Score: 457.603 bits (1176), Expect = 4.773e-157
Identity = 217/345 (62.90%), Postives = 271/345 (78.55%), Query Frame = 0
Query:  405 MAGSVLKMSEKKSLYVRALFDYDPSVDEGIPSKGLNFIFGDIIHVINASDDDWWQARKIDPLGNELGVGLIPSRNRWERKMRSKDRSVRWD--------REGSGKRMGKSKSSND-------------TDGEHENGLDTIISYELVQQIEIEYTRPVIVLGPLKDRINDELISEFPDKFGSCVPHTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQAARLFPIAVFIRPQSVSFIKHVNDDQMTKEQCEKIYARAKRLENDFMQYFTSIVEGSDFDDVYSNVKRLISIHSSTKIWVPANEMF 728
            M+GS+L+MSEK+SL+VR+LFDYDP  DEG+P KGL+F FGDI++V NASD+DWWQA++ID  G EL +G+IPS++RWE+KM+S+DR+V W         R    KR+   KS  +             T    +     + SYELVQQIEIEYTRPVIVLGPLKDRIND+LISE+PD+FGSCVPHTTRPKR FE+DGRDYHFV SRE+ME DIQNHKFIEAGQ NDNLYGTS+ASVKEVAE+ KHCILDVSGNAIKRLQAARL+PIA+F++P+  +FI +VN  ++++EQ +K + RA RLENDF++YFTSIV+G+ ++++Y  VK +I  HS   IWVPANEMF
Sbjct:    1 MSGSMLRMSEKRSLFVRSLFDYDPGADEGVPGKGLHFSFGDILYVTNASDEDWWQAKRIDANGKELELGIIPSKSRWEKKMKSRDRNVHWSSKSKVNSKRPSINKRLPFMKSREEDSDGGGDSGSLASTTDNKDPEEPQVTSYELVQQIEIEYTRPVIVLGPLKDRINDDLISEYPDQFGSCVPHTTRPKRDFEMDGRDYHFVHSRESMEADIQNHKFIEAGQXNDNLYGTSVASVKEVAEKRKHCILDVSGNAIKRLQAARLYPIAIFVKPKDPAFIMNVN--RISEEQADKSFNRASRLENDFLEYFTSIVQGNSYEEIYEKVKVVIQTHSKNCIWVPANEMF 343          
BLAST of discs large 1 vs. L. salmonis genes
Match: EMLSAG00000005586 (supercontig:LSalAtl2s:LSalAtl2s2:2091985:2095229:1 gene:EMLSAG00000005586 transcript:EMLSAT00000005586 description:"maker-LSalAtl2s2-augustus-gene-20.18")

HSP 1 Score: 463.766 bits (1192), Expect = 5.040e-157
Identity = 248/506 (49.01%), Postives = 332/506 (65.61%), Query Frame = 0
Query:  272 DTHYPSSPTIGQMHPLDSRTLQRSVSDEELRIPRDVLLHK--TAAGLGFNIVGGEDGEG--IFISFILAGGPADVS---GQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSS-VALRLLYCPDEYEKFEAKIHSIKSHVMAGSVLKMSEKKSLYVRALFDYDPSVDEGIPSKGLNFIFGDIIHVINASDDDWWQARKIDPLGNELGVGLIPSRNRWERKMRSKDRSVRW---------DREGS----GKR--------------MGKSKSSNDTDGEHE----------------NGLDTIISYELVQQIEIEYTRPVIVLGPLKDRINDELISEFPDKFGSCVPHTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQAARLFPIAVFIRPQSVSFIKHVNDDQMTKEQCEKIYARAKRLENDFMQYFTSIVEGSDFDDVYSNVKRLISIHSSTKIWVPANE 726
            +++Y S+P +       S   +RS      R  R+V L +     GLGFNIVGGED EG  IFISF+LAG PAD+    G++RRGD+IL VN  DL  ATHE AA  LK+     V  R+ Y P+ Y  +EA++H ++   + G++++ S K+SLYVRALFDYDPS D+G+PS+GL F +GDI+HV NASD++WWQARK+ P G+E G+G++PS+ RWERK   K+R +++         DR  +    G+R              M   +  N  D E +                N L  +++YE V +I++E+TRPVI+LGPLKDR+ND+L+ EFPD+FGSCVPHTTRP+R+ EVD RDYHFV S E MERDIQ H FIEAGQYNDNLYGTS+ SV++VA   KHCILDVS NAIKRL  A+L+PIA+FIRP+S+  +  +N  +MT EQ +K + RA +LE+DF +YFT+IV G   +++Y  VK +I   S   IWVP+ E
Sbjct:    8 NSNYSSAPDV-------SSAKRRSDDRHFPRESREVTLERDERGGGLGFNIVGGEDAEGGRIFISFVLAGSPADLCVGGGELRRGDQILAVNEEDLMGATHEHAARILKSVPPGLVRFRVQYRPELYNAYEARLHEMQ-RTLTGTLVRTSPKRSLYVRALFDYDPSRDDGLPSRGLGFCYGDILHVTNASDEEWWQARKVLPNGDEAGLGIVPSKIRWERKQGKKNRRLQFHGSRSSTSLDRSSTHLSGGRRSKGQKIAFSRKFPFMKSRERLNRLDDEEDPPDRGREDIRTTLSNNNTLLPVLTYEPVMEIDLEFTRPVIILGPLKDRLNDDLMREFPDRFGSCVPHTTRPRREHEVDKRDYHFVPSVEKMERDIQTHLFIEAGQYNDNLYGTSVKSVQDVAAMRKHCILDVSANAIKRLHVAQLYPIAIFIRPKSIESVIEMN-KRMTDEQAKKTFERALKLEHDFGEYFTAIVTGDTPEEIYEKVKDVIQEQSGDTIWVPSKE 504          
BLAST of discs large 1 vs. L. salmonis genes
Match: EMLSAG00000006667 (supercontig:LSalAtl2s:LSalAtl2s36:1323669:1338125:1 gene:EMLSAG00000006667 transcript:EMLSAT00000006667 description:"maker-LSalAtl2s36-augustus-gene-13.35")

HSP 1 Score: 158.303 bits (399), Expect = 4.555e-40
Identity = 126/439 (28.70%), Postives = 209/439 (47.61%), Query Frame = 0
Query:  307 VLLHKTAAGLGFNIVGGEDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRLLYCPDEYEKFEAKIHSIKSHVMAGSVLKMSEKKSLYVRALFDYDPSVDEGIPSK--GLNFIFGDIIHVINASDDDWWQARKIDPLGNELGVGLIPSRNRWERKMRSKDRSVRWDRE-------GSGKRMGKSKSSNDTD------GEHENGLDTIISYELVQQI--EIEYTRPVIVLGPL---KDRINDELISEFPDKFGSCVPHTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQAARLFPIAVFIRPQSVSFIKHV----NDDQMTKEQCEKIYARAKRLENDFMQYFTSIVEGSDFDDVYSNVKRLISIHSSTKIW 721
            V + KT   LG   V  ED E + I  I+ GG A+ SG +R GD+IL VN ++L      +    L N   +  L LL  P              S V+  +         +++++  DYDP  D  +P +  G++F  GDI+HVIN  D  WWQA + D   ++   GLIPS +  E++   K   +  D E        +G  +   KS            E E   D I+++E V       +  RPV+++GP    +  +  +L+ +   +F +  PHT+RP+   E D +++HF+ SR   E+DI   KF+E G+Y+ + YGTS  +++ V   GK C+L++    +K L+++   P  VF+ P S+  +K      +D+  + E  ++   RA+ +E+ +  +F  I+  SD    Y  +   I++      W
Sbjct:  252 VKIEKTNEPLG-ATVKNED-EAVVIGRIIRGGVAERSGLLREGDEILEVNEVELRGKNVNEVCDILANMHGT--LTLLVVP--------------SRVLGTNSASSKPNSVMHIKSYIDYDPEDDPYVPCRELGISFQKGDILHVINQCDPHWWQAFR-DGEDDQTLPGLIPSASFQEQREAMKQTIIAQDSEKYVHGTRSTGGFLCAKKSGRKKRRKVPYLSEDEVDSDHILTFEEVALYYPRADRKRPVVLVGPPNIGRXELRKKLMQD-SSRFAAARPHTSRPRGPDEEDSKEFHFI-SRLQFEKDILARKFVEHGEYDKSYYGTSFEAIRSVISSGKICVLNLHPQCLKILKSSDFMPYVVFVAPPSLEKLKRXKMENSDNPASDEDLKETIERAREMEDVYGHFFDMIIIYSDPVKAYQQLLNEINLLEREPQW 669          
BLAST of discs large 1 vs. L. salmonis genes
Match: EMLSAG00000001423 (supercontig:LSalAtl2s:LSalAtl2s1244:119229:120542:1 gene:EMLSAG00000001423 transcript:EMLSAT00000001423 description:"augustus_masked-LSalAtl2s1244-processed-gene-0.4")

HSP 1 Score: 130.568 bits (327), Expect = 1.181e-32
Identity = 105/364 (28.85%), Postives = 171/364 (46.98%), Query Frame = 0
Query:  340 ADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRLLYCP-DEYEKFE-AKIHSIKSHVMAGSVLKMSEKKSLYVRALFDYDPSVDEGIPSK--GLNFIFGDIIHVINASDDDWWQARKIDPLGNELGVGLIPSRNRWERKMRSKDRSVRWDREGSGKRMGKSKSSNDTDGEHENGLDTIISYELVQQIEIEYTRP-----VIVLGP-------LKDRINDELISEFPDKFGSCVPHTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQ-AARLFPIAVFIRPQSVSFIKHVNDDQMTKEQCEKIYARAKRLEN 686
            A  +G I  GD IL +N I +   + ED    +  +   V   +   P +E  K+      S++  ++  S   + ++   +V+ALFDY+P  D  IP    GL+F  GDI+ ++N  D +WWQA+K+     E    LIPS    ER+         +  +        SK    +       +  +   EL    E+   +P     ++++G        LK+RI    I+  P  FG+ +PHT+RPKR  E  G  Y FV S E ME  I+ H+FIE G YN+N YGT ++S++++   G  C+ D    A+K L+ ++   P  +F+    +  +KH+ ++    +    I   +K L N
Sbjct:    2 AXANGLIDIGDVILDINNIPIH--SPEDLMALISMSDKRVNFLVKKTPENELAKYGIPNTPSLRKTIIEKS--NIDQRILYHVKALFDYNPYQDSLIPCAEAGLSFCHGDILAILNKDDANWWQAKKVGDYNYEENGKLIPSLELEERRKAFVPPESNYTSKIGLCGAIISKKKRKSIFRASQSVVQLDRAELQLYEEVTLMKPFRRKVIVIVGASVMGRRTLKNRI----INGDPSSFGAAIPHTSRPKRPEEDSGSRYWFV-STEDMEMGIRQHEFIEYGSYNNNYYGTKLSSIRDIINDGMTCVFDCCVAAMKLLRNSSEFMPYIIFLAAPGMDDMKHIYENSRVSKS---IMTSSKTLSN 353          
BLAST of discs large 1 vs. L. salmonis genes
Match: EMLSAG00000001019 (supercontig:LSalAtl2s:LSalAtl2s116:953600:1003455:1 gene:EMLSAG00000001019 transcript:EMLSAT00000001019 description:"maker-LSalAtl2s116-augustus-gene-10.17")

HSP 1 Score: 99.7525 bits (247), Expect = 9.888e-22
Identity = 89/339 (26.25%), Postives = 148/339 (43.66%), Query Frame = 0
Query:  160 IPYEYDEIILER-GTYGLGFSIAGGVDNPH-AGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPSSPTIGQMHPLDSRTLQRSVSDEELRIPRDVLLHKTAAGLGFNIVGGEDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRLLYCPDEYEKFEAKIHSIKSHVMAGSVLKMSEKKSLYVRALFDYDPSVDEGIPSKG-LNFIFGDIIHVINASDD---DWWQARKIDPL----------GNELGVGLIPSRNRWE 482
            I +EY ++IL R   YG G +++GG DNPH    D SI I+ ++  G A                + ++ + DR+++  N       L+N  +  AV  L+     V LVV +     P++ +    +P                 PR +   K A  +G  + GG D  GIF++ +  G PA   G ++ GDKIL VN +D+   T E+A + L +   ++ L   Y  +EY+                S++ +    S Y++A F Y+      IP K  ++F   D+ HV++   +     WQ  K+DP             ++  G+IP++ R E
Sbjct:  142 IVWEYHQVILSRVPGYGFGIAVSGGRDNPHFTNGDASIAISDVLKSGPA----------------EGKLLINDRVISANNI-----SLENVDYATAVQVLRDSGQTVHLVVKRRVVLPPNTSSNESPYPY----------------PRYISFQK-AGSVGIRLTGGND-VGIFVTAVQPGSPASQKG-LQPGDKILKVNDMDMKGVTREEAVLFLLSLQDTIDLIAQYRKEEYD----------------SIVSLQRGDSFYIKAHFSYE------IPEKNEMSFRKSDVFHVVDTLHNGVVGAWQVFKMDPFMSGLSRSSSSDQQVIKGVIPNKGRAE 418          

HSP 2 Score: 64.3142 bits (155), Expect = 9.578e-11
Identity = 51/209 (24.40%), Postives = 96/209 (45.93%), Query Frame = 0
Query:  519 GLDTIISYELVQQIEIE---YTRPVIVLGPLKDRINDELISEFPDKFGSCVPHTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQAARLFPIAVFIRPQSVSFIKHVNDDQMTKEQ--CEKIYARAKRLENDFMQYFTSIVEGSDFDDVYSNVKRLISIHSSTKIWV 722
            GL    S  L+++  +    + RPV++ GP+     + L+ ++P KF +C      P+     D  D            D+  +K   +G          ++ ++E+ +R KH +LDV+ NA+ +L  A+ +PI +F+R  S   IK        K     +K++ + ++LE  +   FT  +  S+ D+ Y+ +  LI    +  IW+
Sbjct:  536 GLKACPSSLLMKEXSLRHPGFPRPVVIFGPVAXLARERLLRDYPSKF-AC------PQ-----DSSD------------DVSKNK---SGI-------VRLSGIREIMDRRKHALLDVTPNAVDKLNYAQFYPIVIFVRADSKQTIKDCRTGVPKKAHLSSKKLFEQCQKLEKLWGHVFTGTLNLSN-DNWYTKLTDLIDKQQTAPIWM 709          
BLAST of discs large 1 vs. L. salmonis genes
Match: EMLSAG00000000934 (supercontig:LSalAtl2s:LSalAtl2s1165:19602:26919:1 gene:EMLSAG00000000934 transcript:EMLSAT00000000934 description:"maker-LSalAtl2s1165-snap-gene-0.30")

HSP 1 Score: 93.5893 bits (231), Expect = 3.393e-20
Identity = 61/185 (32.97%), Postives = 94/185 (50.81%), Query Frame = 0
Query:  316 LGFNIVGGEDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRLLYCPDEYEKFEAKIHSIKSHVMAGSVLKMSEKKSLYVRALFDYDPSVDEGIPSK--GLNFIFGDIIHVINASDDDWWQARKIDPLGNELGVGLIPSRNRWERKMRSKDRSVRWDREG 498
            +G  I   E    I I+ ++ GG AD SG I  GD+I+ VN I++   +  D    L+ A +++  +L+  P+E  +                   M  +  + +RALFDYDPS D+ IP K  GL F+ G+IIH+++  D  WWQARK       +  GLIPSR   ER++  +   +  + +G
Sbjct:  158 VGATIKAEEATGRILIARVMHGGAADRSGLISVGDEIIEVNGINVEGKSPNDVLRILQMAQNTITFKLI--PNENRQ-------------------MCRESRIRLRALFDYDPSDDKYIPCKEAGLPFVKGEIIHIVSQDDPYWWQARKEQ--DRNMRAGLIPSRALQERRIVQERNEISKEDQG 319          
BLAST of discs large 1 vs. L. salmonis genes
Match: EMLSAG00000010936 (supercontig:LSalAtl2s:LSalAtl2s731:6608:7319:-1 gene:EMLSAG00000010936 transcript:EMLSAT00000010936 description:"maker-LSalAtl2s731-augustus-gene-0.4")

HSP 1 Score: 87.4261 bits (215), Expect = 5.565e-20
Identity = 57/190 (30.00%), Postives = 100/190 (52.63%), Query Frame = 0
Query:  540 VIVLGPL---KDRINDELISEFPDKFGSCVPHTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQAARLFPIAVFIRPQSVSFIKHVNDDQMTKEQCEKIYARAKRLEN--------DFMQYFTSIVEGSDFDDVYSNVKRLISIHSST 718
            +++ GP    K  +  +L+ E+ D FG  + HT+R  R  E +G +Y+F  ++E M +  ++ + IE  +Y+ NLYGTS  S+K+V + G+ C+LDV    ++ L+A+ +    VFIRP S+  +    ++++ K   E       RL+N        D  + F  I+   D +  Y N+K  I  + +T
Sbjct:    8 LVLCGPSGSGKSTLIKKLMEEYTDIFGFSISHTSREPRVGEKNGVEYNF-STKEDMRQLREDQELIEMSEYSGNLYGTSKKSIKKVTDTGRICLLDVDIKGVESLKASDINCKFVFIRPPSLEIL----EERLRKRGTEDEADIQSRLDNVREEIEYGDHEENFDKIIVNDDLNSAYQNLKSFIGQYVTT 192          
BLAST of discs large 1 vs. L. salmonis genes
Match: EMLSAG00000013050 (supercontig:LSalAtl2s:LSalAtl2s9:449519:463146:1 gene:EMLSAG00000013050 transcript:EMLSAT00000013050 description:"maker-LSalAtl2s9-augustus-gene-4.15")

HSP 1 Score: 91.6633 bits (226), Expect = 2.116e-19
Identity = 49/160 (30.63%), Postives = 87/160 (54.37%), Query Frame = 0
Query:  568 HTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQAARLFPIAVFIRPQSVSFIKHVND---DQMTKEQCEKIYARAKRLENDFMQYFTSIVEGSDFDDVYSNVKRLISIHSSTKIWVPA 724
            HT+RPK   E+DG+DY+FV +R   E D+ N +F+E G++  + YGTS+ SV+ V   GK C+L++   +++ L  + L P  +F+ P S++  KH  +   +   +++       A  +E  +  +F S++     + VY  +   I++      WVPA
Sbjct:  550 HTSRPKEDGEIDGQDYNFV-NRSQFEEDLVNKRFLEHGEFEKHYYGTSLDSVRTVINSGKICLLNLQPTSLQILYESDLKPYIIFLTPPSLNVYKHQKNKYGEVFKEDEYRDSVVIATEMEEKYGHHFDSVIPFESVELVYQQLLYEINLLEREPQWVPA 708          
BLAST of discs large 1 vs. L. salmonis genes
Match: EMLSAG00000007926 (supercontig:LSalAtl2s:LSalAtl2s468:58567:60615:1 gene:EMLSAG00000007926 transcript:EMLSAT00000007926 description:"maker-LSalAtl2s468-augustus-gene-0.1")

HSP 1 Score: 86.2705 bits (212), Expect = 2.965e-19
Identity = 63/209 (30.14%), Postives = 104/209 (49.76%), Query Frame = 0
Query:  518 NGLDTIISYELVQQIEIEYT--RPVIVLGPL---KDRINDELISEFPDKFGSCVPHTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAER-GKHCILDVSGNAIKRLQAARLF--PIAVFIRPQSVSFIKHVNDDQMTKEQCEKIYARAKRLENDFMQY------FTSIVEGSDFDDVYSNVKRLI 712
            NG+  + S  L+  I +  T  + +++ GP    K  +  +L +EFP  FG  V HTTR  R  EV G  YHFV +RE M+  +   +FIE  +++ N+YGTS A+ + V     K CILD+    +++++    F  P+ VFI   S+  ++     + T  + E+  AR        ++Y      F +++   D D  Y+ +K  I
Sbjct:   12 NGIRNLQSSRLLPSIIMPKTMHKTLVLCGPSGSGKSTLIKKLTAEFPTAFGFSVSHTTRSPRPGEVHGSAYHFV-TREVMKDMLSKGEFIENAEFSGNMYGTSFAAXEXVXSXDSKICILDIDAQGVRQVKVKEEFLQPLYVFINVPSMEVLEERLKSRNT--ETEESLARRMSAAKAEIEYGTTTGVFDTVIVNDDLDRSYNELKSFI 217          
BLAST of discs large 1 vs. L. salmonis genes
Match: EMLSAG00000007492 (supercontig:LSalAtl2s:LSalAtl2s430:139689:146390:-1 gene:EMLSAG00000007492 transcript:EMLSAT00000007492 description:"maker-LSalAtl2s430-augustus-gene-1.25")

HSP 1 Score: 81.2629 bits (199), Expect = 6.092e-16
Identity = 72/249 (28.92%), Postives = 114/249 (45.78%), Query Frame = 0
Query:  157 KVVIPYEYDEI-------ILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVV------SKGDTHYPSSPTIG----QMHPLDSRTLQRSVSDEELRIPRDVLLHKTAAGLGFNIVGG----EDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRLL 384
            ++VI  E DEI       +++R   GLG SI G    P       +YI++              V+ GGAA +D R+  GD+++ V    G +  L N + EEA   LK  + K+ + V      ++       +P  G      H  DS +    + +     P+ + L +   GLGF+IVGG         I++  +   G A   G ++RGD+I++VN I L   TH+DA   LKN   +V +++L
Sbjct: 1723 RLVIHREDDEIYETFEVELIKRKDRGLGLSIVGKKSGP------GVYISE--------------VVKGGAADSDGRLVQGDQIILVN---GND--LTNSSQEEAAPILKMAQGKITMKVRRLXVGNRQQQRQAPAPVSGLHHVSQHSNDSNSAMAPIIN---GTPKTIRLERGEQGLGFSIVGGFGSPHGDMPIYVKTVFQTGAAAEHGGLKRGDQIVSVNNISLEGLTHQDAVNILKNCEGTVTIQIL 1943          

HSP 2 Score: 80.1073 bits (196), Expect = 1.571e-15
Identity = 64/209 (30.62%), Postives = 98/209 (46.89%), Query Frame = 0
Query:  175 GLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPSSPTIGQMHPLDSRTLQRSVSDEELRIPRDVLLHKTAAGLGFNIVGGEDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRL 383
            GLG SI GG D        +I+I ++   GAA  D RLR               GD+++ V N       L N TH  A+ AL++  +KV LV+ + D                         DE        L+ +   GLG +IVG + G G++IS ++ GG AD  G++ +GD+I+ VN  DL+ ++ E+AA  LK A   + +++
Sbjct: 1656 GLGLSIVGGSDTLLG----AIFIHEVYEKGAAHKDGRLRP--------------GDQILEVMNDN-----LRNVTHSYALHALRQTPNKVRLVIHRED-------------------------DEIYETFEVELIKRKDRGLGLSIVGKKSGPGVYISEVVKGGAADSDGRLVQGDQIILVNGNDLTNSSQEEAAPILKMAQGKITMKV 1816          

HSP 3 Score: 64.6994 bits (156), Expect = 7.447e-11
Identity = 99/391 (25.32%), Postives = 170/391 (43.48%), Query Frame = 0
Query:    1 MPVCKAEAHRALELLEDYYARLDETD----EKELKSAIERVIKIFKSRLFQALLDIQEFY-----ELTLMDEGKSNDIKTTEALEMATRWELTNRPFAKGYEGHLSSTAPGGSSRGGPTLPPQFKEELMSKLPEMRHYDPSSSSTMSEASAMPVASNTSTPAPASKVVIPYEYDEIILERGT-YGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPSSPTIGQMHPLDSRTLQRSVSDEELRIPRDVLLHKTAAGLGFNIVGGEDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVAL 381
            MP+   E   ALELL++   ++ E++      ++K+ +  +I + +S +F ++L+IQ+       ++ L       D   T + E+     + N P A       +ST+P       P L  Q     +S +P      PS +   S      + S     +    +    E   I L +   + LGFS+ G + +   G +  IY+ ++ P G A  D RL             IE GD+++ +     G+ +  N +H++A+  L++    V LVV++G      S  I Q + +D    +  V +        + L    +GLGF I+GG+  +G+ +  IL  G AD  G++R GD IL +N   L     E  A  L+  G+ V L
Sbjct:    1 MPIS-GETRAALELLKEVEKKVKESESLSSNAQIKTDLNTLISVLESPVFTSILNIQDSLRELKRQVHLHPSILPADFDITPSGEL-----VLNLPQASP-----TSTSP-------PALV-QLSSSNISXVP------PSHNGFSSAEGKQGIKSEVELDS-FEDIAQGREIKRIKLYKPEGHSLGFSVVG-LRSEFKG-ELGIYLQEIQPDGLAGKDGRL-------------IE-GDQILAID----GKSLDSNISHQQAINILQRADGYVDLVVARG------SEDITQ-NKIDETPAESCVVEV-------IELVNNGSGLGFGIIGGQK-KGVVVKTILPDGVADSDGRLRAGDFILQINEHWLQGVGSEQVAAVLRGTGNVVKL 330          

HSP 4 Score: 59.6918 bits (143), Expect = 2.559e-9
Identity = 65/224 (29.02%), Postives = 96/224 (42.86%), Query Frame = 0
Query:  161 PYEYDEIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDK----VVLVVSKGDTHYPSSPTIGQMHPLDSRTLQRSVSDEELRI---PRDVLLHKTAAGLGFNIVGG---EDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKN 374
            P +   + L +G  GLG S+AG  D     +  +++I  LIP G A              A D RI++GD ++ V        VL N  H  A + +K   D     V+L   +G +     P      P     L ++   E  +     R + + K   GLG  I+ G   E G G+F+S +     AD +G +  GD IL VN  D   A++E AA  LK+
Sbjct: 1358 PGKLSLVRLNKGIXGLGISLAGHKDR----NQMAVFICGLIPQGNA--------------ARDGRIKIGDSVLEVNG-----KVLHNRCHLNASSLIKNFPDSAVTFVLLTPEEGGSQCAVKPLSANQFP--HGLLNKNNPIERYKKYAGLRQIRIKKEDQGLGIMIIEGKHTEAGTGVFVSDLQPDSAADKAG-LLVGDMILCVNGEDFVGASYESAARVLKS 1555          
BLAST of discs large 1 vs. SwissProt
Match: gi|223590196|sp|Q12959.2|DLG1_HUMAN (RecName: Full=Disks large homolog 1; AltName: Full=Synapse-associated protein 97; Short=SAP-97; Short=SAP97; AltName: Full=hDlg)

HSP 1 Score: 599.356 bits (1544), Expect = 0.000e+0
Identity = 316/604 (52.32%), Postives = 413/604 (68.38%), Query Frame = 0
Query:  166 EIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSK------GDTHYPSSPTIGQMHPLDSRTLQRSV--------------------SDEELRIPRDVLLHKTAAGLGFNIVGGEDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRLLYCPDEYEKFEAKIHSIKSHVM------AGSVLKMSEKKSLYVRALFDYDPSVDEGIPSKGLNFIFGDIIHVINASDDDWWQARKIDPLGNELGVGLIPSRNRWERKMRSKDRSVRWDREGSGK-----RMG----KSKSSNDTDGE--HENGLDTIISYELVQQIEIEYTRPVIVLGPLKDRINDELISEFPDKFGSCVPHTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQAARLFPIAVFIRPQSVSFIKHVNDDQMTKEQCEKIYARAKRLENDFMQYFTSIVEGSDFDDVYSNVKRLISIHSSTKIWVPANE 726
            EI L +G  GLGFSIAGGV N H   D SIY+TK+I              +GGAA  D ++++GD+L+ V N       L+  THEEAVTALK   D V L V+K       D + P   T     P+D+     S                      DE  R PR V+LH+ + GLGFNIVGGEDGEGIFISFILAGGPAD+SG++R+GD+I++VN++DL  A+HE AA ALKNAG +V +   Y P+EY +FEAKIH ++  +M          L+ S+K+SLYVRALFDYD + D G+PS+GLNF FGDI+HVINASDD+WWQAR++ P G    VG+IPS+ R E+K R++ ++V+++ +   K      MG    K  +SN +D E  +    + ++SYE V Q E+ YTRPVI+LGP+KDRIND+LISEFPDKFGSCVPHTTRPKR +EVDGRDYHFV SRE ME+DIQ HKFIEAGQYN++LYGTS+ SV+EVAE+GKHCILDVSGNAIKRLQ A+L+PI++FI+P+S+  I  +N  ++T+EQ  K + RA +LE +F ++FT+IV+G   +D+Y+ VK++I   S + IWVPA E
Sbjct:  319 EIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKII--------------EGGAAHKDGKLQIGDKLLAVNNV-----CLEEVTHEEAVTALKNTSDFVYLKVAKPTSMYMNDGYAPPDITNSSSQPVDNHVSPSSFLGQTPASPARYSPVSKAVLGDDEITREPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTIVAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEKKERARLKTVKFNSKTRDKGEIPDDMGSKGLKHVTSNASDSESSYRGQEEYVLSYEPVNQQEVNYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVREVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKSMENIMEMN-KRLTEEQARKTFERAMKLEQEFTEHFTAIVQGDTLEDIYNQVKQIIEEQSGSYIWVPAKE 902          

HSP 2 Score: 196.823 bits (499), Expect = 1.412e-51
Identity = 151/461 (32.75%), Postives = 217/461 (47.07%), Query Frame = 0
Query:    1 MPVCKAEAHRALELLEDYYARLDETDEKELKSAIERVIKIFKSRLFQALLDIQEFYELTLMDEGKSND-IKTTEALEMATRWELTNRP----FAKGYEGHLSSTAPGGSSRGGPTLP-----PQFKEELMSKLPEMRHYDPSSSSTMSEASAMPVASNTSTPAPA---------------------SKVVIP-----------------------------YEYDEIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPSSPTIGQMHPLDSRTLQRSVSDEELRIPRDVLLHKTAAGLGFNIVGGEDGE------GIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRL-----LYCPDEY 390
            MPV K +  RAL LLE+Y ++L +T++++L+S+IERVI IF+S LFQAL+DIQEFYE+TL+D  K  D  K +E ++    WE+++ P     ++     LS +      +   T P     PQ   E++   PE+ H    + S +         S+ S   P                      + V++P                             YEY+EI LERG  GLGFSIAGG DNPH G D+SI+ITK+I GGAA+ D RLR              V D ++ V      E  + + TH +AV ALK+    V L V +                      ++ VS++ + I     L K   GLGF+I GG   +       I+++ I+ GG A   G+++ GDK+L VN + L   THE+A  ALKN    V L++     +Y  D Y
Sbjct:    1 MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVINIFQSNLFQALIDIQEFYEVTLLDNPKCIDRSKPSEPIQPVNTWEISSLPSSTVTSETLPSSLSPSVEKYRYQDEDTPPQEHISPQITNEVIG--PELVHVSEKNLSEIENVHGFVSHSHISPIKPTEAVLPSPPTVPVIPVLPVPAENTVILPTIPQANPPPVLVNTDSLETPTYVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLR--------------VNDCILRV-----NEVDVRDVTHSKAVEALKEAGSIVRLYVKR----------------------RKPVSEKIMEIK----LIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMYMNDGY 414          
BLAST of discs large 1 vs. SwissProt
Match: gi|59797853|sp|Q811D0.1|DLG1_MOUSE (RecName: Full=Disks large homolog 1; AltName: Full=Embryo-dlg/synapse-associated protein 97; Short=E-dlg/SAP97; AltName: Full=Synapse-associated protein 97; Short=SAP-97; Short=SAP97)

HSP 1 Score: 596.275 bits (1536), Expect = 0.000e+0
Identity = 317/617 (51.38%), Postives = 420/617 (68.07%), Query Frame = 0
Query:  154 PASKVVIPYEYDEIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKG----------------------DTHYPSSPTIGQM--HPLDSRTLQRSV--SDEELRIPRDVLLHKTAAGLGFNIVGGEDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRLLYCPDEYEKFEAKIHSIKSHVM------AGSVLKMSEKKSLYVRALFDYDPSVDEGIPSKGLNFIFGDIIHVINASDDDWWQARKIDPLGNELGVGLIPSRNRWERKMRSKDRSVRWDREGSGKR------MG----KSKSSNDTDGE--HENGLDTIISYELVQQIEIEYTRPVIVLGPLKDRINDELISEFPDKFGSCVPHTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQAARLFPIAVFIRPQSVSFIKHVNDDQMTKEQCEKIYARAKRLENDFMQYFTSIVEGSDFDDVYSNVKRLISIHSSTKIWVPANE 726
            PAS+ ++     EI L +G  GLGFSIAGGV N H   D SIY+TK+I              +GGAA  D ++++GD+L+ V +       L+  THEEAVTALK   D V L V+K                       D H   S  +GQ    P     + ++V   DE  R PR V+LH+ + GLGFNIVGGEDGEGIFISFILAGGPAD+SG++R+GD+I++VN++DL  A+HE AA ALKNAG +V +   Y P+EY +FEAKIH ++  +M          L+ S+K+SLYVRALFDYD + D G+PS+GLNF FGDI+HVINASDD+WWQAR++ P G    VG+IPS+ R E+K R++ ++V+++ +  G +      MG    K  +SN +D E  +    + ++SYE V Q E+ YTRPVI+LGP+KDR+ND+LISEFPDKFGSCVPHTTRPKR +EVDGRDYHFV SRE ME+DIQ HKFIEAGQYN++LYGTS+ SV+ VAE+GKHCILDVSGNAIKRLQ A+L+PI++FI+P+S+  I  +N  ++T+EQ  K + RA +LE +F ++FT+IV+G   +D+Y+ VK++I   S   IWVPA E
Sbjct:  312 PASEKIM-----EIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKII--------------EGGAAHKDGKLQIGDKLLAVNSV-----CLEEVTHEEAVTALKNTSDFVYLKVAKPTSMYINDGYAPPDITNSSSQSVDNHVSPSSCLGQTPTSPARYSPISKAVLGDDEITREPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTIVAQYRPEEYSRFEAKIHDLREQMMNSSVSSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFRFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEKKERARLKTVKFNSKTRGDKGEIPDDMGSKGLKHVTSNASDSESSYRGQEEYVLSYEPVNQQEVNYTRPVIILGPMKDRVNDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVRAVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKSMENIMEMN-KRLTEEQARKTFERAMKLEQEFTEHFTAIVQGDTLEDIYNQVKQIIEEQSGPYIWVPAKE 903          

HSP 2 Score: 209.149 bits (531), Expect = 6.802e-56
Identity = 160/484 (33.06%), Postives = 226/484 (46.69%), Query Frame = 0
Query:    1 MPVCKAEAHRALELLEDYYARLDETDEKELKSAIERVIKIFKSRLFQALLDIQEFYELTLMDEGKSND-IKTTEALEMATRWELTNRP----FAKGYEGHLSSTAPGGSSRGGPTLPP-----QFKEELMSKLPEMRHYD----------------------------PSSSSTMSEASAMPVASNTSTPAPASKVVIP----------------------YEYDEIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPSSPTIGQMHPLDSRTLQRSVSDEELRIPRDVLLHKTAAGLGFNIVGGEDGE------GIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRL-----LYCPDEY---EKFEAKIHSIKSHVMAGSVL 410
            MPV K +  RAL LLE+Y ++L +T++++L+S+IERVI IF+S LFQAL+DIQEFYE+TL+D  K  D  K  E ++  T WE+ + P     ++   G LS        +    LPP     Q   E++   PE+ H                              P SS  +    A+PV + ++   P++    P                      YEY+EI LERG  GLGFSIAGG DNPH G D+SI+ITK+I GGAA+ D RLRV D        R+   D              + + TH +AV ALK+    V L V +     P+S  I                        ++ L K   GLGF+I GG   +       I+++ I+ GG A   G+++ GDK+L VN++ L   THE+A  ALKN    V L++     +Y  D Y   +   +   S+ +HV   S L
Sbjct:    1 MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVINIFQSNLFQALIDIQEFYEVTLLDNPKCVDHSKQCEPVQPVTTWEIASLPSTAVTSETLPGSLSPPVEKYRYQDEEVLPPEHISPQVTNEVLG--PELVHVSEKNLSEIENVHGFVSHSHISPIKPTEAVPPSSPIVPVTPALPVPAESTVVLPSAPQANPPPVLVNTDSLETPTYVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVND-----CILRVNEAD--------------VRDVTHSKAVEALKEAGSIVRLYVKR---RKPASEKI-----------------------MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMYINDGYAPPDITNSSSQSVDNHVSPSSCL 437          
BLAST of discs large 1 vs. SwissProt
Match: gi|2497505|sp|Q62696.1|DLG1_RAT (RecName: Full=Disks large homolog 1; AltName: Full=Synapse-associated protein 97; Short=SAP-97; Short=SAP97)

HSP 1 Score: 592.808 bits (1527), Expect = 0.000e+0
Identity = 317/614 (51.63%), Postives = 414/614 (67.43%), Query Frame = 0
Query:  166 EIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKG----------------------DTHYPSSPTIGQM--HPLDSRTLQRSV--SDEELRIPRDVLLHKTAAGLGFNIVGGEDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRLLYCPDEYEKFEAKIHSIKSHVM------AGSVLKMSEKKSLYVRALFDYDPSVDEGIPSKGLNFIFGDIIHVINASDDDWWQARKIDPLGNELGVGLIPSRNRWERKMRSKDRSVRWDREGSGKR------MG----KSKSSNDTDGE---HENGL------DTIISYELVQQIEIEYTRPVIVLGPLKDRINDELISEFPDKFGSCVPHTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQAARLFPIAVFIRPQSVSFIKHVNDDQMTKEQCEKIYARAKRLENDFMQYFTSIVEGSDFDDVYSNVKRLISIHSSTKIWVPANEMF 728
            EI L +G  GLGFSIAGGV N H   D SIY+TK+I              +GGAA  D ++++GD+L+ V +       L+  THEEAVTALK   D V L  +K                       D H   S  +GQ    P     + ++V   DE  R PR V+LH+ + GLGFNIVGGEDGEGIFISFILAGGPAD+SG++R+GD+I++VN++DL  A+HE AA ALKNAG +V +   Y P+EY +FEAKIH ++  +M          L+ S+K+SLYVRALFDYD + D G+PS+GLNF FGDI+HVINASDD+WWQAR++ P G    VG+IPS+ R E+K R++ ++V+++ +  G +      MG    K  +SN +D E   HE G       + ++SYE V Q E+ YTRPVI+LGP+KDR+ND+LISEFPDKFGSCVPHTTRPKR +EVDGRDYHFV SRE ME+DIQ HKFIEAGQYN++LYGTS+ SV+ VAE+GKHCILDVSGNAIKRLQ A+L+PI++FI+P+S+  I  +N  ++T EQ  K + RA RLE +F ++FT+IV+G   +D+Y+ VK++I   S   IWVPA E  
Sbjct:  318 EIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKII--------------EGGAAHKDGKLQIGDKLLAVNSV-----CLEEVTHEEAVTALKNTSDFVYLKAAKPTSMYINDGYAPPDITNSSSQSVDNHVSPSSYLGQTPASPARYSPISKAVLGDDEITREPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTIVAQYRPEEYSRFEAKIHDLRETMMNSSVSSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEKKERARLKTVKFNSKTRGDKGEIPDDMGSKGLKHVTSNASDSESSYHEYGCSKGGQEEYVLSYEPVNQQEVNYTRPVIILGPMKDRVNDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVRAVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKSMENIMEMN-KRLTDEQARKTFERAVRLEQEFTEHFTAIVQGDTLEDIYNQVKQIIEEQSGPYIWVPAKEKL 911          

HSP 2 Score: 201.445 bits (511), Expect = 3.779e-53
Identity = 162/494 (32.79%), Postives = 222/494 (44.94%), Query Frame = 0
Query:    1 MPVCKAEAHRALELLEDYYARLDETDEKELKSAIERVIKIFKSRLFQALLDIQEFYELTLMDEGKSND-IKTTEALEMATRWELTNRPFAKGYEGHLSSTA------PGGSS--------RGGPTLP-----PQFKEELMSKLPEMRHYD----------------------------PSSSSTMSEASAMPVASNTSTPAPASKVVIP----------------------YEYDEIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPSSPTIGQMHPLDSRTLQRSVSDEELRIPRDVLLHKTAAGLGFNIVGGEDGE------GIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRL-----LYCPDEY---EKFEAKIHSIKSHVMAGSVL 410
            MPV K +  RAL LLE+Y ++L +T++++L+S+IERVI IF+S LFQAL+DIQEFYE+TL+D  K  D  K  E ++    WE           G LSS A      PGG S        +    LP     PQ   E++   PE+ H                              P SS  +    A+PV + +    P++    P                      YEY+EI LERG  GLGFSIAGG DNPH G D+SI+ITK+I GGAA+ D RLRV D        R+   D              + + TH +AV ALK+    V L V +                            +  R   ++ L K   GLGF+I GG   +       I+++ I+ GG A   G+++ GDK+L VN++ L   THE+A  ALKN    V L+      +Y  D Y   +   +   S+ +HV   S L
Sbjct:    1 MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVISIFQSNLFQALIDIQEFYEVTLLDNPKCVDHSKQCEPVQPGNPWE----------SGSLSSAAVTSESLPGGLSPPVEKYRYQDEEVLPSERISPQVPNEVLG--PELVHVSEKSLSEIENVHGFVSHSHISPIKPTEAVPPSSPIVPVTPALPVPAESPVVLPSTPQANPPPVLVNTDSLETPTYVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVND-----CILRVNEAD--------------VRDVTHSKAVEALKEAGSIVRLYVKR---------------------------RKAFRKNHEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKAAKPTSMYINDGYAPPDITNSSSQSVDNHVSPSSYL 436          
BLAST of discs large 1 vs. SwissProt
Match: gi|68052302|sp|Q5PYH5.1|DLG1L_DANRE (RecName: Full=Discs large homolog 1-like protein; AltName: Full=Synapse-associated protein 97B; Short=SAP-97B; Short=SAP97B)

HSP 1 Score: 589.726 bits (1519), Expect = 0.000e+0
Identity = 309/596 (51.85%), Postives = 405/596 (67.95%), Query Frame = 0
Query:  166 EIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSK------GDTHYPS--------------SPTIGQMHPLD-------SRTLQRSVSDEEL-RIPRDVLLHKTAAGLGFNIVGGEDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRLLYCPDEYEKFEAKIHSIKSHVM------AGSVLKMSEKKSLYVRALFDYDPSVDEGIPSKGLNFIFGDIIHVINASDDDWWQARKIDPLGNELGVGLIPSRNRWERKMRSKDRSVRWDREGSGKRMGKSKSSNDTDGEHENGLDT-IISYELVQQIEIEYTRPVIVLGPLKDRINDELISEFPDKFGSCVPHTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQAARLFPIAVFIRPQSVSFIKHVNDDQMTKEQCEKIYARAKRLENDFMQYFTSIVEGSDFDDVYSNVKRLISIHSSTKIWVPANE 726
            EI L +G  GLGFSIAGGV N H   D SIY+TK+I              +GGAA  D R+++GD+L+ V +       L+  THE AVTALK   D V L V+K       D+  P               SP      PL        S T + +V D+++ R PR V+LH+   GLGFNIVGGEDGEGIFISFILAGGPAD+ G++R+GD++++VN IDL  ATHE AA ALKNAG +V +   Y P+EY +FEAKIH ++  +M          L+ S+K+SLYVRALFDYD + D G+PS+GLNF FGDI+HV+NASDD+WWQAR++   G    +G+IPS+ R E+K R++ ++V+++     K   K  + +D   + ++G +  ++SYE V Q E+ Y+RPVI+LGP+KDR+ND+LISEFPDKFGSCVPHTTRPKR +EVDGRDYHFV SRE MERDIQ HKFIEAGQYN +LYGTS+ SV+EVAE+GKHCILDVSGNAIKRLQ A L+PI +FI+P+SV  I  +N  ++T+EQ  K Y RA +LE +FM++FT+IV+G   +++Y  VK++I   S   IWV + E
Sbjct:  254 EIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKII--------------EGGAAHKDGRLQIGDKLLAVNSS-----CLEEVTHEHAVTALKNTPDVVYLKVAKPNSVFMNDSFAPPDITNSYSQHMENHISPPSYLSQPLPPVHSGRFSPTPKTTVGDDDVTREPRKVVLHRGTTGLGFNIVGGEDGEGIFISFILAGGPADLCGELRKGDRLVSVNGIDLRGATHEQAAAALKNAGQTVTIVAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHVVNASDDEWWQARQVTAQGEVEEMGVIPSKRRVEKKERARLKTVKFN----SKSREKGDNPDDMLSKGQSGQEEYVLSYEPVSQQEVNYSRPVIILGPMKDRVNDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVVSREQMERDIQEHKFIEAGQYNSHLYGTSVQSVREVAEKGKHCILDVSGNAIKRLQVAMLYPIGIFIKPKSVENIMEMN-KRLTEEQGRKTYDRAMKLEQEFMEHFTAIVQGDTLEEIYDQVKQIIEEQSGPYIWVQSKE 825          

HSP 2 Score: 128.642 bits (322), Expect = 2.091e-29
Identity = 101/285 (35.44%), Postives = 135/285 (47.37%), Query Frame = 0
Query:  108 GPTLPPQFKEELMSKLPEMRHYDPSSSSTMSEASAMPVASNTSTPAPASKV---VIPYEYDEIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPSSPTIGQMHPLDSRTLQRSVSDEELRIPRDVLLHKTAAGLGFNIVGGEDGE------GIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRL 383
            GP+  P  KEE               S    +A+  PV  NT +   A  V      +EY+EI LERG  GLGFSIAGG DNPH G D SI+ITK+IPGGAA+ D RLR              V D ++ V      E  + + TH +AV ALK+    V L V +                      ++S S++ + I     L K   GLGF+I GG   +       I+++ I+ GG A   G+++ GDK+L VN+  L   THE A  ALKN    V L++
Sbjct:  100 GPS--PVVKEESPPSPSTPLSNPYPQSPVSVQANPPPVVVNTESLDSAPYVNGTEADFEYEEITLERGNSGLGFSIAGGTDNPHIGEDPSIFITKVIPGGAAAQDGRLR--------------VNDVILRVN-----EVDVRDVTHSKAVEALKEAGSLVRLYVRR----------------------RKSASEKVMEIK----LIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKLLAVNSSCLEEVTHEHAVTALKNTPDVVYLKV 337          
BLAST of discs large 1 vs. SwissProt
Match: gi|123892312|sp|Q28C55.1|DLG1_XENTR (RecName: Full=Disks large homolog 1)

HSP 1 Score: 588.956 bits (1517), Expect = 0.000e+0
Identity = 305/631 (48.34%), Postives = 409/631 (64.82%), Query Frame = 0
Query:  166 EIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHY------------------------------PSSPTIGQMHPLDSRTLQRSVSDEELRIPRDVLLHKTAAGLGFNIVGGEDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRLLYCPDEYEKFEAKIHSIKSHVM------AGSVLKMSEKKSLYVRALFDYDPSVDEGIPSKGLNFIFGDIIHVINASDDDWWQARKIDPLGNELGVGLIPSRNRWERKMRSKDRSVRWDREGSGKR--------------------------------MGKSKSSNDTDGE--HENGLDTIISYELVQQIEIEYTRPVIVLGPLKDRINDELISEFPDKFGSCVPHTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQAARLFPIAVFIRPQSVSFIKHVNDDQMTKEQCEKIYARAKRLENDFMQYFTSIVEGSDFDDVYSNVKRLISIHSSTKIWVPANE 726
            +I L +G  GLGFSIAGGV N H   D SIY+TK+I              +GGAA  D R+++GD+L+ V         L+  +HE+AVTALK   D V L V+K  T Y                              P  P+ G+  P     L+    D+  R PR V+L +   GLGFNIVGGEDGEGIFISFILAGGPAD+SG++++GD+I++VN +DL  ATHE AA ALKNAG +V +   Y P+EY +FEAKIH ++  +M          L+ S+K+SLYVRALFDYD + D G+PS+GLNF FGDI+HV+NASDD+WWQAR++   G    +G+IPS+ R E+K R++ ++V+++ +  G +                                + +  +SN +D E  +    + ++SYE V Q E+ Y+RPVI+LGP KDR+ND+LISEFP+KFGSCVPHTTRPKR +E+DGRDYHFV SRE ME+DIQ+H+FIEAGQYN +LYGTS+ SVKEVAERGKHCILDVSGNAIKRLQ A+L+PIA+FI+P+SV  I  ++  ++T+EQ  K Y RA +LE +F ++FT+IV+G   +++Y+ +K++I   SST IWVPA E
Sbjct:  318 DIKLVKGPKGLGFSIAGGVGNQHIPGDNSIYVTKII--------------EGGAAHKDGRLQIGDKLLAVNTV-----CLEEVSHEDAVTALKNTSDFVNLKVAKPTTMYMNDNYAPPDITNSYSQQVDNHISPSGFIGHPLPPSPGRYSPAPKGMLE---DDDLTREPRKVVLQRGTTGLGFNIVGGEDGEGIFISFILAGGPADLSGELQKGDRIMSVNGVDLKSATHEQAAAALKNAGQTVTIVAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHVVNASDDEWWQARQVTADGESEEIGVIPSKRRVEKKERARLKTVKFNSKARGDKGQSFNDKRKKNLFSRKFPFYKNKDQSEMETSDVDQHVTSNASDSESSYRGQEEYVLSYEPVNQQEVNYSRPVIILGPTKDRVNDDLISEFPEKFGSCVPHTTRPKRDYEIDGRDYHFVTSREQMEKDIQDHRFIEAGQYNSHLYGTSVQSVKEVAERGKHCILDVSGNAIKRLQIAQLYPIAIFIKPKSVENIIEMS-KRVTEEQGRKTYERAMKLEQEFTEHFTAIVQGDTLEEIYNQIKQIIEEQSSTFIWVPAKE 925          

HSP 2 Score: 140.969 bits (354), Expect = 3.045e-33
Identity = 99/269 (36.80%), Postives = 133/269 (49.44%), Query Frame = 0
Query:  135 STMSEASAMPVASNT--STPAPASKVVIPYEYDEIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPSSPTIGQMHPLDSRTLQRSVSDEELRIPRDVLLHKTAAGLGFNIVGGEDGE------GIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRL-----LYCPDEY 390
            S+  +A+  PV  NT   TPA  +     YEY+EI LERGT GLGFSIAGG DNPH G D SI+ITK+I GGAA+ D RLR              V D ++ V      E  + + TH +AV ALK+    V L V +               P+  + +             D+ L K   GLGF+I GG   +       I+++ I+ GG A   G+++ GDK+L VN + L   +HEDA  ALKN    V L++     +Y  D Y
Sbjct:  190 SSTPQANPPPVIVNTDLETPAYVNGTDAEYEYEEITLERGTSGLGFSIAGGTDNPHIGDDISIFITKIISGGAAAQDGRLR--------------VNDCILRV-----NEVDVHDVTHSKAVEALKEAGSIVRLYVRR-------------RKPVTEKIM-------------DIKLVKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKLLAVNTVCLEEVSHEDAVTALKNTSDFVNLKVAKPTTMYMNDNY 413          

HSP 3 Score: 97.4413 bits (241), Expect = 1.285e-19
Identity = 47/88 (53.41%), Postives = 65/88 (73.86%), Query Frame = 0
Query:    1 MPVCKAEAHRALELLEDYYARLDETDEKELKSAIERVIKIFKSRLFQALLDIQEFYELTLMDEGKSND-IKTTEALEMATRWELTNRP 87
            MPV K +  RAL LLE+Y  +L +T++K+L+ +IERVI IF+S LFQAL+DIQEFYE+TL+D  KS+D  K TE ++    WE ++ P
Sbjct:    1 MPVRKQDTQRALTLLEEYRCKLHQTEDKQLRKSIERVIGIFQSNLFQALIDIQEFYEVTLLDNPKSSDNAKPTEPVQTINTWEYSSLP 88          
BLAST of discs large 1 vs. SwissProt
Match: gi|68052060|sp|Q5PYH7.1|DLG2_DANRE (RecName: Full=Disks large homolog 2; AltName: Full=Postsynaptic density protein 93; Short=PSD-93)

HSP 1 Score: 581.252 bits (1497), Expect = 0.000e+0
Identity = 318/650 (48.92%), Postives = 413/650 (63.54%), Query Frame = 0
Query:  166 EIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPSSP------------------------------------TIGQMHPLDSRTL-----QRSVSDEE------------LRIPRDVLLHKTAAGLGFNIVGGEDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRLLYCPDEYEKFEAKIHSIKSHVMAGSV------LKMSEKKSLYVRALFDYDPSVDEGIPSKGLNFIFGDIIHVINASDDDWWQARKIDPLGNELGVGLIPSRNRWERKMRSKDRSVRWD-REGSGKRMG-------------------KSKSSNDTDGE--HENGLDTIISYELVQQIEIEYTRPVIVLGPLKDRINDELISEFPDKFGSCVP--------HTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQAARLFPIAVFIRPQSVSFIKHVNDDQMTKEQCEKIYARAKRLENDFMQYFTSIVEGSDFDDVYSNVKRLISIHSSTKIWVPANE 726
            EI L +G  GLGFSIAGGV N H   D SIY+TK+I              DGGAA  D R++VGDRL+ V N+      L+  THEEAV  LK   D V L V K  + Y S P                                    + G+  PL    L      R+ S +E            LR PR ++LHK + GLGFNIVGGEDGEGIF+SFILAGGPAD+SG++RRGD+IL+VN IDL  ATHE AA ALK AG +V +   Y P+EY +FEAKIH ++  +M  S+      L+ ++K+SLYVRALFDY+ + D G+PS+GL+F +GDI+HVINASDD+WWQAR++ P G+   +G+IPS+ R ERK R++ ++V+++ + GS    G                   K+K +++ DG     +  + I+SYE V + EI Y RPVI+LGP+KDRIND+LISEFPDKFGSCVP         TTRPKR +EVDGRDYHF+ SRE ME+DIQ HKFIEAGQYNDNLYGTS+ SVK VAERGKHCILDVSGNAIKRLQ A+L+PIA+FI+P+S+  +  +N  ++T+EQ +K Y RA +LE +F +YFT++V+G   +D+Y+  K +I   S   IW+P+ E
Sbjct:  250 EIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKII--------------DGGAAQKDGRLQVGDRLLMVNNY-----TLEEVTHEEAVAILKNTSDVVYLKVGKPTSVYLSDPYGPPDITHSFSPAMENHISSPGNNGTLEYKSSLPPISPGRYSPLPKHLLGEEDINRNPSLDEMEGHRFDSQHFQLREPRKIVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDQILSVNGIDLRGATHEQAAAALKGAGQTVTIIAQYRPEEYGRFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRALFDYERAKDSGLPSQGLSFRYGDILHVINASDDEWWQARRVTPEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGSLDSKGSFSEKRRKNFIFSRKFPFYKNKDADEQDGSDSERSQEELILSYEPVIRQEINYARPVIILGPMKDRINDDLISEFPDKFGSCVPPANSSDQEDTTRPKRDYEVDGRDYHFMASREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVKYVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSIESLMEMN-KRLTEEQAKKTYDRAMKLEQEFGEYFTALVQGDTLEDIYNQCKMVIEEQSGPYIWIPSKE 879          

HSP 2 Score: 127.102 bits (318), Expect = 6.817e-29
Identity = 96/288 (33.33%), Postives = 134/288 (46.53%), Query Frame = 0
Query:  117 EELMSKLPEMRHYDPSSSSTMSEASAMPVASNTSTPAPASKV---VIPYEYDEIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPSSPTIGQMHPLDSRTLQRSVSDEELRIPRDVLLHKTAAGLGFNIVGGEDGE------GIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRL-----LYCPDEY 390
            E+ +S++  +  Y   S  +  +AS  P+  NT T      V    I YE++EI LERG  GLGFSIAGG DNPH G D  I+ITK+IPGGAA+ D RLRV D      +S +                      +H +AV ALK     V L V +                   R +  +V+        ++ L K   GLGF+I GG   +       I+++ I+ GG A   G+++ GD++L VN   L   THE+A   LKN    V L++     +Y  D Y
Sbjct:  103 EKNLSEIENVHGYVSHSHISPLKASPAPIIVNTDTLESVPYVNGTEIEYEFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNESDV-------------------SEVSHSKAVEALKAAGSIVRLYVRR------------------RRPMLETVT--------EIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYTLEEVTHEEAVAILKNTSDVVYLKVGKPTSVYLSDPY 345          
BLAST of discs large 1 vs. SwissProt
Match: gi|218512007|sp|Q92796.2|DLG3_HUMAN (RecName: Full=Disks large homolog 3; AltName: Full=Neuroendocrine-DLG; AltName: Full=Synapse-associated protein 102; Short=SAP-102; Short=SAP102; AltName: Full=XLMR)

HSP 1 Score: 572.007 bits (1473), Expect = 0.000e+0
Identity = 309/618 (50.00%), Postives = 403/618 (65.21%), Query Frame = 0
Query:  166 EIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSK----------------------GDTH------------------YPSSPTIGQMHPLDSRTLQRSVSDEE--LRIPRDVLLHKTAAGLGFNIVGGEDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRLLYCPDEYEKFEAKIHSIKSHVMAGSV------LKMSEKKSLYVRALFDYDPSVDEGIPSKGLNFIFGDIIHVINASDDDWWQARKIDPLGNELGVGLIPSRNRWERKMRSKDRSVRWDREGSGKRMGKSKSSNDTDGEHENGL---------DTIISYELVQQIEIEYTRPVIVLGPLKDRINDELISEFPDKFGSCVPHTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQAARLFPIAVFIRPQSVSFIKHVNDDQMTKEQCEKIYARAKRLENDFMQYFTSIVEGSDFDDVYSNVKRLISIHSSTKIWVPANE 726
            E+ L +G  GLGFSIAGG+ N H   D SIYITK+I              +GGAA  D R+++GDRL+ V N       L +  HEEAV +LK   D V L V+K                       D H                  YP+ P   Q+ P     + R +  EE   R PR ++LHK + GLGFNIVGGEDGEGIF+SFILAGGPAD+SG++RRGD+IL+VN ++L  ATHE AA ALK AG SV +   Y P+EY +FE+KIH ++  +M  S+      L+ SEK+SLYVRALFDYD + D  +PS+GL+F +GDI+HVINASDD+WWQAR + P G    +G+IPS+ R E+K R++ ++V++       R G  +S+ D  G  ++           D I+SYE V + EI Y RPVI+LGP+KDR+ND+LISEFP KFGSCVPHTTRP+R  EVDG+DYHFV SRE ME+DIQ++KFIEAGQ+NDNLYGTSI SV+ VAERGKHCILDVSGNAIKRLQ A+L+PIA+FI+P+S+  +  +N  Q T EQ  KIY +A +LE +F +YFT+IV+G   +++Y+ +K++I   S   IWVP+ E
Sbjct:  226 EVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKII--------------EGGAAQKDGRLQIGDRLLAVNNT-----NLQDVRHEEAVASLKNTSDMVYLKVAKPGSLHLNDMYAPPDYASTFTALADNHISHNSSLGYLGAVESKVSYPAPP---QVPPTRYSPIPRHMLAEEDFTREPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFH-----ARTGMIESNRDFPGLSDDYYGAKNLKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQ-TYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPE 815          

HSP 2 Score: 112.464 bits (280), Expect = 2.778e-24
Identity = 94/275 (34.18%), Postives = 126/275 (45.82%), Query Frame = 0
Query:  162 YEYDEIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPSSPTIGQMHPLDSRTLQRSVSDEELRIPRDVLLHKTAAGLGFNIVGGEDGE------GIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRL----------LYCPDEY-EKFEAKIHSIKSHVMAGSVLKMSEKKSLY 419
            ++Y+EI+LERG  GLGFSIAGG+DNPH   D  I+ITK+IPGGAA++D RL V D                V   N    E  +    H  AV ALK+    V LVV +     P   TI                        +V L K   GLGF+I GG   +       I+I+ I+ GG A   G+++ GD++L VN  +L    HE+A  +LKN    V L++          +Y P +Y   F A   +  SH  +   L   E K  Y
Sbjct:  127 FKYEEIVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVND---------------CVLRVN----EVDVSEVVHSRAVEALKEAGPVVRLVVRRRQ---PPPETI-----------------------MEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKNTSDMVYLKVAKPGSLHLNDMYAPPDYASTFTALADNHISHNSSLGYLGAVESKVSY 356          
BLAST of discs large 1 vs. SwissProt
Match: gi|2497507|sp|P70175.1|DLG3_MOUSE (RecName: Full=Disks large homolog 3; AltName: Full=Synapse-associated protein 102; Short=SAP-102; Short=SAP102)

HSP 1 Score: 567.77 bits (1462), Expect = 0.000e+0
Identity = 307/627 (48.96%), Postives = 406/627 (64.75%), Query Frame = 0
Query:  166 EIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSK----------------------GDTH------------------YPSSPTIGQMHPLDSRTLQRSVSDEE--LRIPRDVLLHKTAAGLGFNIVGGEDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRLLYCPDEYEKFEAKIHSIKSHVMAGSV------LKMSEKKSLYVRALFDYDPSVDEGIPSKGLNFIFGDIIHVINASDDDWWQARKIDPLGNELGVGLIPSRNRWERKMRSKDRSVRW------------------DREGSGKRMGKSKSSNDTDGEHENGLDTIISYELVQQIEIEYTRPVIVLGPLKDRINDELISEFPDKFGSCVPHTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQAARLFPIAVFIRPQSVSFIKHVNDDQMTKEQCEKIYARAKRLENDFMQYFTSIVEGSDFDDVYSNVKRLISIHSSTKIWVPANE 726
            E+ L +G  GLGFSIAGG+ N H   D SIYITK+I              +GGAA  D R+++GDRL+ V N       L +  HEEAV +LK   D V L V+K                       D H                  YP+ P   Q+ P     + R +  EE   R PR ++LHK + GLGFNIVGGEDGEGIF+SFILAGGPAD+SG++RRGD+IL+VN ++L  ATHE AA ALK AG SV +   Y P+EY +FE+KIH ++  +M  S+      L+ SEK+SLYVRALFDYD + D  +PS+GL+F +GDI+HVINASDD+WWQAR + P G    +G+IPS+ R E+K R++ ++V++                  D  G+    G + +++D++   +   D I+SYE V + EI Y RPVI+LGP+KDR+ND+LISEFP KFGSCVPHTTRP+R  EVDG+DYHFV SRE ME+DIQ++KFIEAGQ+NDNLYGTSI SV+ VAERGKHCILDVSGNAIKRLQ A+L+PIA+FI+P+S+  +  +N  Q T EQ  KI+ +A +LE +F +YFT+IV+G   +++Y+ +K++I   S   IWVP+ E
Sbjct:  244 EVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKII--------------EGGAAQKDGRLQIGDRLLAVNNT-----NLQDVRHEEAVASLKNTSDMVYLKVAKPGSIHLNDMYAPPDYASTFTALADNHISHNSSLGYLGAVESKVTYPAPP---QVPPTRYSPIPRHMLAEEDFTREPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRDFPGLSDDYYGAKNLKGVTSNTSDSESSSKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQ-TYEQANKIFDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPE 847          

HSP 2 Score: 114.39 bits (285), Expect = 6.673e-25
Identity = 114/375 (30.40%), Postives = 159/375 (42.40%), Query Frame = 0
Query:   89 AKGYEGHLSSTAPGGSSRGGPTLPPQFKEELM----------------SKLPEMRHYDP--------SSSSTMSEASAMPVASNTSTPAPASKVVIP---YEYDEIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPSSPTIGQMHPLDSRTLQRSVSDEELRIPRDVLLHKTAAGLGFNIVGGEDGE------GIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRL----------LYCPDEY-EKFEAKIHSIKSHVMAGSVLKMSEKKSLY 419
            + GY G+ S T P   S+ G T  P+ K +L+                   P++    P        ++     +AS  P+  N     P+  V      ++Y+EI+LERG  GLGFSIAGG+DNPH   D  I+ITK+IPGGAA++D RL V D                V   N    E  +    H  AV ALK+    V LVV +     P   TI                        +V L K   GLGF+I GG   +       I+I+ I+ GG A   G+++ GD++L VN  +L    HE+A  +LKN    V L++          +Y P +Y   F A   +  SH  +   L   E K  Y
Sbjct:   48 SSGYGGYSSQTLP---SQAGATPTPRTKAKLIPTGRDVGPVPPKPVPGKSTPKLNGSGPGWWPECTCTNRDWYEQASPAPLLVNPEALEPSLSVNGSDGMFKYEEIVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVND---------------CVLRVN----EVDVSEVVHSRAVEALKEAGPVVRLVVRRRQ---PPPETI-----------------------MEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKNTSDMVYLKVAKPGSIHLNDMYAPPDYASTFTALADNHISHNSSLGYLGAVESKVTY 374          
BLAST of discs large 1 vs. SwissProt
Match: gi|2497508|sp|Q62936.1|DLG3_RAT (RecName: Full=Disks large homolog 3; AltName: Full=PSD-95/SAP90-related protein 1; AltName: Full=Synapse-associated protein 102; Short=SAP-102; Short=SAP102)

HSP 1 Score: 567.385 bits (1461), Expect = 0.000e+0
Identity = 307/627 (48.96%), Postives = 406/627 (64.75%), Query Frame = 0
Query:  166 EIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSK----------------------GDTH------------------YPSSPTIGQMHPLDSRTLQRSVSDEE--LRIPRDVLLHKTAAGLGFNIVGGEDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRLLYCPDEYEKFEAKIHSIKSHVMAGSV------LKMSEKKSLYVRALFDYDPSVDEGIPSKGLNFIFGDIIHVINASDDDWWQARKIDPLGNELGVGLIPSRNRWERKMRSKDRSVRW------------------DREGSGKRMGKSKSSNDTDGEHENGLDTIISYELVQQIEIEYTRPVIVLGPLKDRINDELISEFPDKFGSCVPHTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQAARLFPIAVFIRPQSVSFIKHVNDDQMTKEQCEKIYARAKRLENDFMQYFTSIVEGSDFDDVYSNVKRLISIHSSTKIWVPANE 726
            E+ L +G  GLGFSIAGG+ N H   D SIYITK+I              +GGAA  D R+++GDRL+ V N       L +  HEEAV +LK   D V L V+K                       D H                  YP+ P   Q+ P     + R +  EE   R PR ++LHK + GLGFNIVGGEDGEGIF+SFILAGGPAD+SG++RRGD+IL+VN ++L  ATHE AA ALK AG SV +   Y P+EY +FE+KIH ++  +M  S+      L+ SEK+SLYVRALFDYD + D  +PS+GL+F +GDI+HVINASDD+WWQAR + P G    +G+IPS+ R E+K R++ ++V++                  D  G+    G + +++D++   +   D I+SYE V + EI Y RPVI+LGP+KDR+ND+LISEFP KFGSCVPHTTRP+R  EVDG+DYHFV SRE ME+DIQ++KFIEAGQ+NDNLYGTSI SV+ VAERGKHCILDVSGNAIKRLQ A+L+PIA+FI+P+S+  +  +N  Q T EQ  KI+ +A +LE +F +YFT+IV+G   +++Y+ +K++I   S   IWVP+ E
Sbjct:  244 EVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKII--------------EGGAAQKDGRLQIGDRLLAVNNT-----NLQDVRHEEAVASLKNTSDMVYLKVAKPGSLHLNDMYAPPDYASTFTALADNHISHNSSLGYLGAVESKVTYPAPP---QVPPTRYSPIPRHMLAEEDFTREPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRDFPGLSDDYYGAKNLKGVTSNTSDSESSSKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQ-TYEQANKIFDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPE 847          

HSP 2 Score: 115.546 bits (288), Expect = 2.863e-25
Identity = 115/375 (30.67%), Postives = 159/375 (42.40%), Query Frame = 0
Query:   89 AKGYEGHLSSTAPGGSSRGGPTLPPQFKEELM----------------SKLPEMRHYDPS--------SSSTMSEASAMPVASNTSTPAPASKVVIP---YEYDEIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPSSPTIGQMHPLDSRTLQRSVSDEELRIPRDVLLHKTAAGLGFNIVGGEDGE------GIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRL----------LYCPDEY-EKFEAKIHSIKSHVMAGSVLKMSEKKSLY 419
            + GY G+ S T P   S+ G T  P+ K +L+                   P++    PS        +     +AS  P+  N     P+  V      ++Y+EI+LERG  GLGFSIAGG+DNPH   D  I+ITK+IPGGAA++D RL V D                V   N    E  +    H  AV ALK+    V LVV +     P   TI                        +V L K   GLGF+I GG   +       I+I+ I+ GG A   G+++ GD++L VN  +L    HE+A  +LKN    V L++          +Y P +Y   F A   +  SH  +   L   E K  Y
Sbjct:   48 SSGYGGYSSQTLP---SQAGATPTPRTKAKLIPTGRDVGPVPPKPVPGKNTPKLNGSGPSWWPECTCTNRDWYEQASPAPLLVNPEALEPSLSVNGSDGMFKYEEIVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVND---------------CVLRVN----EVDVSEVVHSRAVEALKEAGPVVRLVVRRRQ---PPPETI-----------------------MEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKNTSDMVYLKVAKPGSLHLNDMYAPPDYASTFTALADNHISHNSSLGYLGAVESKVTY 374          
BLAST of discs large 1 vs. SwissProt
Match: gi|2497501|sp|Q62108.1|DLG4_MOUSE (RecName: Full=Disks large homolog 4; AltName: Full=Postsynaptic density protein 95; Short=PSD-95; AltName: Full=Synapse-associated protein 90; Short=SAP-90; Short=SAP90)

HSP 1 Score: 559.681 bits (1441), Expect = 0.000e+0
Identity = 293/611 (47.95%), Postives = 396/611 (64.81%), Query Frame = 0
Query:  154 PASKVVIPYEYDEIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSK------GDTHYPSSPTIGQMHPLDSRTLQRS-------------------------VSDEEL-RIPRDVLLHKTAAGLGFNIVGGEDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRLLYCPDEYEKFEAKIHSIKSHVMAGSV------LKMSEKKSLYVRALFDYDPSVDEGIPSKGLNFIFGDIIHVINASDDDWWQARKIDPLGNELGVGLIPSRNRWERKMRSKDRSVRWDREGSGKRMGKSKSSNDTDGEHENGLDTIISYELVQQIEIEYTRPVIVLGPLKDRINDELISEFPDKFGSCVPHTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQAARLFPIAVFIRPQSVSFIKHVNDDQMTKEQCEKIYARAKRLENDFMQYFTSIVEGSDFDDVYSNVKRLISIHSSTKIWVPANE 726
            PA K++      EI L +G  GLGFSIAGGV N H   D SIY+TK+I              +GGAA  D R+++GD+++ V +       L++  HE+AV ALK   D V L V+K       D++ P   T      LD+     S                         + +E++ R PR +++H+ + GLGFNIVGGEDGEGIFISFILAGGPAD+SG++R+GD+IL+VN +DL  A+HE AAIALKNAG +V +   Y P+EY +FEAKIH ++  +M  S+      L+ + K+  Y+RALFDYD + D G  S+ L+F FGD++HVI+ASD++WWQAR++        +G IPS+ R ER+  S+ ++  W         G S  S   +       D+++SYE V Q+E+ Y RP+I+LGP KDR ND+L+SEFPDKFGSCVPHTTRPKR++E+DGRDYHFV SRE ME+DIQ HKFIEAGQYN +LYGTS+ SV+EVAE+GKHCILDVS NA++RLQAA L PIA+FIRP+S+  +  +N  ++T+EQ  K + RA +LE +F + F++IVEG  F+++Y  VKR+I   S   IWVPA E
Sbjct:  154 PAEKII------EIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKII--------------EGGAAHKDGRLQIGDKILAVNSVG-----LEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFHFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDW---------GSSSGSQGRE-------DSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEIN-KRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARE 722          

HSP 2 Score: 129.028 bits (323), Expect = 1.242e-29
Identity = 99/279 (35.48%), Postives = 136/279 (48.75%), Query Frame = 0
Query:  124 PEMRHYDPSSSSTMSEASAMPVASNTST-PAPASKVVI-----PYEYDEIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPSSPTIGQMHPLDSRTLQRSVSDEELRIPRDVLLHKTAAGLGFNIVGGEDGE------GIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRLLYCPDEY 390
            P + H   S +   ++A++ PV  NT T  AP  ++ +       EY+EI LERG  GLGFSIAGG DNPH G D SI+ITK+IPGGAA+ D RLR              V D ++ V      E  +   TH  AV ALK+    V L V                       ++R    E++    ++ L K   GLGF+I GG   +       I+++ I+ GG A   G+++ GDKIL VN++ L    HEDA  ALKN    V L++    + Y
Sbjct:   20 PPLEH---SPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLR--------------VNDSILFVN-----EVDVREVTHSAAVEALKEAGSIVRLYV-----------------------MRRKPPAEKI---IEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAY 250          
BLAST of discs large 1 vs. nr
Match: gi|1325301983|ref|XP_023332535.1| (disks large 1 tumor suppressor protein-like [Eurytemora affinis])

HSP 1 Score: 723.776 bits (1867), Expect = 0.000e+0
Identity = 360/591 (60.91%), Postives = 448/591 (75.80%), Query Frame = 0
Query:  163 EYDEIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYP----SSPTIGQMHPLDSR-TLQRSVSDEEL-RIPRDVLLHKTAAGLGFNIVGGEDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRLLYCPDEYEKFEAKIHSIKSHVMAGSVLKMSEKKSLYVRALFDYDPSVDEGIPSKGLNFIFGDIIHVINASDDDWWQARKIDPLGNELGVGLIPSRNRWERKMRSKDRSVRW-----DRE---GSGKRMGKSKS-----------SNDTDGEHENGLDTIISYELVQQIEIEYTRPVIVLGPLKDRINDELISEFPDKFGSCVPHTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQAARLFPIAVFIRPQSVSFIKHVNDDQMTKEQCEKIYARAKRLENDFMQYFTSIVEGSDFDDVYSNVKRLISIHSSTKIWVPANEMF 728
            ++  + L +G+ GLGF+IAGG++N H   D  IY+TK              VM+GGAA  D RI VGDRLV VKN P G+F L++C+HEEAV ALK  K+KV LV+SK D HYP     SPT  QM P   +  + RSVS+EEL R PR V L K  AGLGFNIVGGEDGEGIFISFILAGGPADVSGQ++RGD+I +VN IDLS ATHE AA ALK AG++V ++L Y PD+Y KFEAKIHS+K  +++GS+L+MSEKKSLYVR+LFDYDP+ DEGIPS+GL F FGDI+HV NASD+DWWQAR++ P G+E  +GL+PSR RWE+KMRS+ RSV W     DR+     G+++   KS            ND +  H    + + +YE+VQQ++IEYTRPVIVLGPLKDRIND+LISE+P+ FGSCVPHTTRP+R++EVD RDYHFV SRE ME DIQNHKFIEAGQYNDNLYGTSIASVK VAE+GKHCILDVSGNAIKRLQAAR++PIA+F++P+ V+FI  VN  ++++EQ +K + RA RLEN+F++YFT++VEG   D +Y  VK++I  +S+  IWVP+NE F
Sbjct:  262 DFINVELMKGSKGLGFTIAGGINNQHIPGDNGIYVTK--------------VMEGGAAFNDGRIAVGDRLVAVKNLPTGDFYLEDCSHEEAVKALKASKEKVYLVISKVDNHYPFEVSPSPTFTQMDPYKPQYKVPRSVSEEELIRAPRTVSLVKGPAGLGFNIVGGEDGEGIFISFILAGGPADVSGQVKRGDQICSVNGIDLSNATHEAAAQALKGAGNTVHMKLQYKPDDYNKFEAKIHSLKKQIISGSMLRMSEKKSLYVRSLFDYDPTKDEGIPSRGLGFKFGDILHVTNASDEDWWQARRVLPQGDEGEMGLVPSRTRWEKKMRSRHRSVGWRSQTDDRKKYSSLGRKLPFMKSRDEMSSETDATGNDGESLHSKDEEFVPTYEMVQQVQIEYTRPVIVLGPLKDRINDDLISEYPESFGSCVPHTTRPRREYEVDSRDYHFVASREAMEADIQNHKFIEAGQYNDNLYGTSIASVKAVAEKGKHCILDVSGNAIKRLQAARIYPIAIFVKPRDVNFIISVN-KKLSEEQAKKSFDRACRLENEFIEYFTAMVEGETIDGIYEKVKQVIVENSAKNIWVPSNENF 837          

HSP 2 Score: 234.187 bits (596), Expect = 1.743e-62
Identity = 165/418 (39.47%), Postives = 225/418 (53.83%), Query Frame = 0
Query:    1 MPVCKAEAHRALELLEDYYARLDETDEKELKSAIERVIKIFKSRLFQALLDIQEFYELTLMDEGKSNDIKTTEALEMATRWELTNRPFAKGYEGHLSSTAPGGSSRG-----GPTLPPQFKEELMSKLPEMRHYDPSSSSTMS--EASAMPVASNTSTP---------APASKVVIPYEYDEIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVS-KGDTHYPSSPTIGQMHPLDSRTLQRSVSDEELRIPRDVLLHKTAAGLGFNIVGGEDGE------GIFISFILAGGPADVSGQIRRGDKILTVNAID-----LSRATHEDAAIALKNAGSSVALRLLYCPDEY 390
            MPV KAEAHRALELLEDYY RL E DEK+L++AIERVI+IFKSRLFQ+LLDIQEFYELTLMDE KS + KT+EAL+MA+RWE+                 P G S+G       +LP Q ++E++ +L  + +    +S ++S  E    P+  +   P         + ++  +  +EYD+I LERG  GLGFSIAGG DNPH  +D SI+ITK+I GGAA+ D RLRV D               ++T  N   G  V++   H  AV ALK+  + V L V  K  T+  S   I                        +V L K + GLGF I GG + +      GI+++ ++ GG A   G+I  GD+++ V  +      L   +HE+A  ALK +   V L +    + Y
Sbjct:    1 MPVTKAEAHRALELLEDYYTRLSEEDEKQLRAAIERVIRIFKSRLFQSLLDIQEFYELTLMDESKSINTKTSEALQMASRWEV---------------AGPPGQSKGLELGQDISLPDQQRDEMLRQLAHIANEAVPASRSLSRREPVLAPLPVSAPVPVPPPASVPRSVSAAGIENWEYDDISLERGGAGLGFSIAGGTDNPHVPNDNSIFITKIIDGGAAAHDGRLRVND---------------IITHVN---GVCVIE-VPHTAAVDALKRAGNSVHLTVKRKRQTNGTSGDFI------------------------NVELMKGSKGLGFTIAGGINNQHIPGDNGIYVTKVMEGGAAFNDGRIAVGDRLVAVKNLPTGDFYLEDCSHEEAVKALKASKEKVYLVISKVDNHY 360          
BLAST of discs large 1 vs. nr
Match: gi|1227982859|ref|XP_021923054.1| (disks large 1 tumor suppressor protein isoform X3 [Zootermopsis nevadensis])

HSP 1 Score: 647.121 bits (1668), Expect = 0.000e+0
Identity = 329/626 (52.56%), Postives = 429/626 (68.53%), Query Frame = 0
Query:  166 EIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPS---------------------SPTIGQMHPLDSRTLQRSVSDEEL-RIPRDVLLHKTAAGLGFNIVGGEDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRLLYCPDEYEKFEAKIHSIKSH----VMAGSVLKMSEKKSLYVRALFDYDPSVDEGIPSKGLNFIFGDIIHVINASDDDWWQARKIDPLGNELGVGLIPSRNRWERKMRSKDRSVRWDREGSGKRM----------------------GKSKSSNDTDGEH---------------ENGLDTIISYELVQQIEIEYTRPVIVLGPLKDRINDELISEFPDKFGSCVPHTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQAARLFPIAVFIRPQSVSFIKHVNDDQMTKEQCEKIYARAKRLENDFMQYFTSIVEGSDFDDVYSNVKRLISIHSSTKIWVPANEMF 728
            EI L +GT GLGFSIAGG+ N H   D  IY+TK              +MDGGAA  D R++VGD+LV V+N P GE  L+N THEEAV  LK  +++VVL+V+K +T Y                       S ++     L + T  R+VS+E++ R  R V+L K   GLGFNIVGGEDGEGIF+SFILAGGPAD+SG++RRGD+IL+VN I+L  ATHE+AA ALK AG +V +   Y P+EY +FEAKIH +K      +M+G++++ S+K+SLYVRALFDYDP  D+G+PS+GL F +GDI+HV NASDD+WWQAR++   G E G+G++PS+ RWERK R++DR+V++    +G  +                       KSK     DG                 E G +T++SYE VQQ++I+YTRPVI+LGPLKDR+ND+LISEFPDKFGSCVPHTTRPKR++EVDGRDYHFV SRE MERDIQNH FIEAGQYNDNLYGTS+ASV++VAE+GKHCILDVSGNAIKRLQ A+LFPIA+FI+P+SV  I  +N  +MT+EQ +K + RA ++E +F +YFT++V+G   +D+Y  VK +I   +   IWVP+ +  
Sbjct:  373 EIELLKGTKGLGFSIAGGIGNQHIPGDNGIYVTK--------------IMDGGAAQIDGRLQVGDKLVAVRNTPVGEKNLENVTHEEAVATLKATQERVVLLVAKPETAYMPPPPDVSSTPPPPPPLATPVPYSDSLNASMALQAST-PRAVSEEDISREVRTVVLGKGNTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDQILSVNGINLRSATHEEAAQALKGAGQTVTIVAQYRPEEYNRFEAKIHDLKQQMSQQIMSGTLMRTSQKRSLYVRALFDYDPIKDDGLPSRGLPFRYGDILHVTNASDDEWWQARRVLSSGEEEGMGIVPSKRRWERKQRARDRTVKFQGHAAGGVILDKQCTLDRKKKNFSFSRKFPFMKSKDDKSEDGSDQEPFMLCYTQDDTHTEGGEETVLSYEAVQQLQIQYTRPVIILGPLKDRVNDDLISEFPDKFGSCVPHTTRPKREYEVDGRDYHFVASREQMERDIQNHLFIEAGQYNDNLYGTSVASVRDVAEKGKHCILDVSGNAIKRLQVAQLFPIAIFIKPKSVDSIMEMN-KRMTEEQAKKTFERAMKMEQEFGEYFTAVVQGDTPEDIYVKVKEVIQEQAGPTIWVPSKDQL 982          

HSP 2 Score: 126.716 bits (317), Expect = 3.468e-26
Identity = 88/231 (38.10%), Postives = 119/231 (51.52%), Query Frame = 0
Query:  162 YEYDEIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPSSPTIGQMHPLDSRTLQRSVSDEELRIPRDVLLHKTAAGLGFNIVGGEDGE------GIFISFILAGGPADVSGQIRRGDKILTVNAI-----DLSRATHEDAAIALKNAGSSVAL 381
            +EY+EI+LERG  GLGFSIAGG DNPH G DT+I+ITKLIPGGAA+ D RLRV        D+ ++V D  VT+   P          H  AV ALK+  ++V L V +  T            P + R L+             + L K   GLGF+I GG   +      GI+++ I+ GG A + G+++ GDK++ V        +L   THE+A   LK     V L
Sbjct:  273 WEYEEIVLERGGAGLGFSIAGGTDNPHIGDDTAIFITKLIPGGAAAADGRLRV-------NDTILQVND--VTLVEVP----------HAAAVDALKRAGNEVRLYVRRRRT------------PGNMRLLE-------------IELLKGTKGLGFSIAGGIGNQHIPGDNGIYVTKIMDGGAAQIDGRLQVGDKLVAVRNTPVGEKNLENVTHEEAVATLKATQERVVL 459          
BLAST of discs large 1 vs. nr
Match: gi|333033759|dbj|BAK23256.1| (discs large 1 [Gryllus bimaculatus])

HSP 1 Score: 644.81 bits (1662), Expect = 0.000e+0
Identity = 327/624 (52.40%), Postives = 438/624 (70.19%), Query Frame = 0
Query:  166 EIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHY-PSSPTIGQMHPLD---------------SRTLQ----RSVSDEEL-RIPRDVLLHKTAAGLGFNIVGGEDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRLLYCPDEYEKFEAKIHSIKSH----VMAGSVLKMSEKKSLYVRALFDYDPSVDEGIPSKGLNFIFGDIIHVINASDDDWWQARKIDPLGNELGVGLIPSRNRWERKMRSKDRSVRW---------DREGSGKRMGKS---------------KSSNDTDGE-----------HENGLD-TIISYELVQQIEIEYTRPVIVLGPLKDRINDELISEFPDKFGSCVPHTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQAARLFPIAVFIRPQSVSFIKHVNDDQMTKEQCEKIYARAKRLENDFMQYFTSIVEGSDFDDVYSNVKRLISIHSSTKIWVPANEMF 728
            EI L +G+ GLGFSIAGG+ N H   D  IY+TK              +MDGGAA  D R+ VGD+LV V+N P G+  L+N THEEAV  LK  +++VVL+V+K +++Y P  P +    P                 S TL     R+VS+E++ R  R V+L+K + GLGFNIVGGEDGEGIF+SFILAGGPAD+SG++RRGD+IL+VN ++L  ATHE+AA ALK AG +V +   Y P+EY +FE+KIH +K      +M+G++++ S+K+SLYVRALFDYDP+ D+G+PS+GL F +GDI+HV NASDD+WWQAR++   G E G+G++PS+ RWERK R++DR+V++         D++ +  R  K+               KS + +D E           H  G + T++SYE VQQ++I+YTRPVI+LGPLKDR+ND+LISEFPDKFGSCVPHTTRPKR++EVDGRDYHFV SRE MERDIQNH FIEAGQYNDNLYGTS+ASV+EVAE+GKHCILDVSGNAIKRLQ A+LFP+A+FI+P+S+  I  +N  +MT+EQ +K + RA ++E +F +YFT++V+G   +D+Y  VK +I   +   IWVP+ +  
Sbjct:  274 EIELVKGSKGLGFSIAGGIGNQHIPGDNGIYVTK--------------IMDGGAAQIDGRLVVGDKLVAVRNTPHGDKNLENVTHEEAVATLKATQERVVLLVAKPESNYMPPPPDVSNTPPPPPPIEPQIPYSDSHNTSMTLPASTPRAVSEEDVSREVRTVVLNKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDQILSVNGVNLRNATHEEAAQALKGAGQTVTIVAQYKPEEYNRFESKIHDLKQQMSQQIMSGTLMRTSQKRSLYVRALFDYDPNKDDGLPSRGLPFRYGDILHVTNASDDEWWQARRVLATGEEEGMGIVPSKRRWERKQRARDRTVKFQGHVPGVILDKQSTLDRKKKNFSFSRKFPFMKSKDDKSEDGSDQEPFMLCYTQDDTHTEGAEETVLSYEAVQQMQIQYTRPVIILGPLKDRVNDDLISEFPDKFGSCVPHTTRPKREYEVDGRDYHFVASREQMERDIQNHLFIEAGQYNDNLYGTSVASVREVAEKGKHCILDVSGNAIKRLQVAQLFPVAIFIKPKSIDSIMEMN-KRMTEEQAKKTFERAMKMEQEFGEYFTAVVQGDTPEDIYMKVKEVIQEQAGPTIWVPSKDQL 882          

HSP 2 Score: 223.402 bits (568), Expect = 1.959e-58
Identity = 160/416 (38.46%), Postives = 215/416 (51.68%), Query Frame = 0
Query:    1 MPVCKAEAHRALELLEDYYARLDETDEKELKSAIERVIKIFKSRLFQALLDIQEFYELTLMDEGKSNDIKTTEALEMATRWELTNRPFAKGY---EGHLSSTAPGG------SSRGGPTLPPQFKEELMSKLPEMRHYDPSSSSTMSEASAMPVASNTSTPA----PASKVVIP-----------YEYDEIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPSSPTIGQMHPLDSRTLQRSVSDEELRIPRDVLLHKTAAGLGFNIVGGEDGE------GIFISFILAGGPADVSGQIRRGDKILTVNAI-----DLSRATHEDAAIALKNAGSSVAL 381
            MPV K +AHRALELLEDY+ +L +  +K+L+ AIERVI+IFKSRLFQALLDIQEFYELTL+D+ KS   KT E + +A +WE ++ P    Y   +G   S  PG       +   GP   P   +EL    P+            ++   M + SN S        A   ++P           +E++EI+LERG  GLGFSIAGG DNPH G DT+IYITKLIPGGAA+ D RLRV        D+ ++V D  VTV + P          H  AV ALK+  ++V L V +     PS  T+ ++                        L K + GLGF+I GG   +      GI+++ I+ GG A + G++  GDK++ V        +L   THE+A   LK     V L
Sbjct:    1 MPVRK-QAHRALELLEDYHEKLTKPQDKQLRLAIERVIRIFKSRLFQALLDIQEFYELTLLDDTKSIQQKTAETIRIANKWEASDGPITPTYGNNDGAPDSRLPGSMLPLSPAFLAGPDRRPLSPDELQLAFPQ-----------RNDTGRMLIKSNDSWQGHDSDQAHTPLLPGDNKHVNGDGEWEFEEIVLERGGAGLGFSIAGGTDNPHIGDDTAIYITKLIPGGAAAADGRLRV-------NDTILQVND--VTVVDVP----------HAAAVDALKRAGNEVRLYVRR--RRQPSHVTLLEIE-----------------------LVKGSKGLGFSIAGGIGNQHIPGDNGIYVTKIMDGGAAQIDGRLVVGDKLVAVRNTPHGDKNLENVTHEEAVATLKATQERVVL 360          
BLAST of discs large 1 vs. nr
Match: gi|1284992693|ref|XP_023022488.1| (disks large 1 tumor suppressor protein isoform X4 [Leptinotarsa decemlineata])

HSP 1 Score: 637.491 bits (1643), Expect = 0.000e+0
Identity = 327/626 (52.24%), Postives = 425/626 (67.89%), Query Frame = 0
Query:  166 EIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPS-------SPTIG---------QMHPLDSRTLQ--------RSVSDEEL-RIPRDVLLHKTAAGLGFNIVGGEDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRLLYCPDEYEKFEAKIHSIKSH----VMAGSVLKMSEKKSLYVRALFDYDPSVDEGIPSKGLNFIFGDIIHVINASDDDWWQARKIDPLGNELGVGLIPSRNRWERKMRSKDRSVRW--------------DR----------------------EGSGKRMGKSKSSNDTDGEHENGLDTIISYELVQQIEIEYTRPVIVLGPLKDRINDELISEFPDKFGSCVPHTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQAARLFPIAVFIRPQSVSFIKHVNDDQMTKEQCEKIYARAKRLENDFMQYFTSIVEGSDFDDVYSNVKRLISIHSSTKIWVPANE 726
            EI L +G  GLGFSIAGG+ N H   D  IY+TK              VMDGGAA  D R+ VGD+LV V++   GE  L+N THE+AV  LK  +D+VVLVV+K D  + +       SP +           MH + S  L         R+VS E++ R  R ++LHK  +GLGFNIVGGEDGEGIFISFILAGGPAD  G++RRGD+I++VN ++L  ATHE+AA+ALK    +V + + Y P+EY +FEAKIH +K      V  G++L+ S+K+SLYVRALFDYDP  D+G+PS+GL F +GDI+HV NASDD+WWQAR++   G+E G+G++PS+ RWERK R++DRSV++              DR                      +GS +    S   ND +   + G + ++SYE VQQ++I YTRPVI+LGPLKDRIND+LISEFPDKFGSCVPHTTR KR++EVDGRDYHFV SRE ME+DIQNH FIEAGQYNDNLYGTS+ASV+EVA++GKHCILDVSGNAIKRLQ A+L+PIA+FI+P+SV  I  +N  +M +EQ +K + RA ++E +F +YFT++V+G   +D+Y+ VK +I   S  KIWVP  E
Sbjct:  317 EIELVKGNKGLGFSIAGGIGNQHIPGDNGIYVTK--------------VMDGGAAQVDGRLLVGDKLVAVRDAVKGEVNLENVTHEDAVATLKTTQDRVVLVVAKPDITFNAPASDASYSPQLSTKASHGYADSMHSVHSSNLTLHHPPSTPRAVSAEDITRDVRSIVLHKGGSGLGFNIVGGEDGEGIFISFILAGGPADQCGELRRGDQIISVNGVNLRNATHEEAALALKGTNQTVNIVVQYRPEEYNRFEAKIHDLKQQMANPVTGGTLLRTSQKRSLYVRALFDYDPMKDDGLPSRGLAFHYGDILHVTNASDDEWWQARRVLNTGDEQGMGIVPSKRRWERKQRARDRSVKFQGHMPNILEKQSTLDRKKKNFSFSRKFPFMKSKDDKSEDGSDQEQTPSDQPNDNEKPPQCGEENVLSYEPVQQLQINYTRPVIILGPLKDRINDDLISEFPDKFGSCVPHTTRAKREYEVDGRDYHFVSSREQMEKDIQNHLFIEAGQYNDNLYGTSVASVREVADKGKHCILDVSGNAIKRLQVAQLYPIAIFIKPKSVESIMEMN-KRMNEEQAKKTFERAVKMEQEFGEYFTAVVQGDTPEDIYNEVKEVIEEQSGPKIWVPTKE 927          

HSP 2 Score: 123.25 bits (308), Expect = 3.149e-25
Identity = 88/238 (36.97%), Postives = 117/238 (49.16%), Query Frame = 0
Query:  162 YEYDEIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPSSPTIGQMHPLDSRTLQRSVSDEELRIPRDVLLHKTAAGLGFNIVGGEDGE------GIFISFILAGGPADVSGQIRRGDKILTV-----NAIDLSRATHEDAAIALKNAGSSVALRLLYCPD 388
            +EY+EIILERG  GLGFSIAGG DNPH G DT+IYITKLIPGGAAS              AD R+ V D +++V + P    V+D   H  AV ALKK  + V L + +                                   ++ L K   GLGF+I GG   +      GI+++ ++ GG A V G++  GDK++ V       ++L   THEDA   LK     V L ++  PD
Sbjct:  217 WEYEEIILERGGSGLGFSIAGGTDNPHIGDDTAIYITKLIPGGAAS--------------ADGRLLVNDSILSVNDVP----VID-VPHALAVDALKKAGNTVKLCIRRRRQPRNMRLM-------------------------EIELVKGNKGLGFSIAGGIGNQHIPGDNGIYVTKVMDGGAAQVDGRLLVGDKLVAVRDAVKGEVNLENVTHEDAVATLKTTQDRVVL-VVAKPD 409          

HSP 3 Score: 120.168 bits (300), Expect = 3.360e-24
Identity = 58/92 (63.04%), Postives = 71/92 (77.17%), Query Frame = 0
Query:    1 MPVCKAEAHRALELLEDYYARLDETDEKELKSAIERVIKIFKSRLFQALLDIQEFYELTLMDEGKSNDIKTTEALEMATRWELTNRPFAKGY 92
            MPV K EAHRALELLEDY+++L +  +K+L+ AIERVI+IFKSRLFQALLDIQEFYELTL+DE KS   KT E + +A +WE  + P    Y
Sbjct:    1 MPVRKQEAHRALELLEDYHSKLIKPQDKQLRLAIERVIRIFKSRLFQALLDIQEFYELTLLDENKSVQEKTAETIRIANKWEANDGPIIPPY 92          
BLAST of discs large 1 vs. nr
Match: gi|1008428398|ref|XP_015840483.1| (PREDICTED: disks large 1 tumor suppressor protein isoform X5 [Tribolium castaneum])

HSP 1 Score: 637.106 bits (1642), Expect = 0.000e+0
Identity = 329/624 (52.72%), Postives = 427/624 (68.43%), Query Frame = 0
Query:  166 EIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHY--PSSPT----------------------IGQMHPLDSRTLQRSVSDEEL-RIPRDVLLHKTAAGLGFNIVGGEDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRLLYCPDEYEKFEAKIHSIK---SHVMAGSVLKMSEKKSLYVRALFDYDPSVDEGIPSKGLNFIFGDIIHVINASDDDWWQARKIDPLGNELGVGLIPSRNRWERKMRSKDRSVRW--------DREGSGKRMGKS----------KSSNDT-----------------DGEHENGLDTIISYELVQQIEIEYTRPVIVLGPLKDRINDELISEFPDKFGSCVPHTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQAARLFPIAVFIRPQSVSFIKHVNDDQMTKEQCEKIYARAKRLENDFMQYFTSIVEGSDFDDVYSNVKRLISIHSSTKIWVPANE 726
            EI L +G  GLGFSIAGG+ N H   D  IY+TK              VM+GGAA  D R+ VGD+LV V++   GE  L+N THE+AVT LK  +D+VVLVV+K D+ +  P+S T                      +   HP  +    R+VS E++ R  R V+L K  +GLGFNIVGGEDGEGIFISFILAGGPAD+SG++RRGD+IL+VN ++L  ATHE+AA  LK   S+V + + Y P+EY +FEAKIH +K   SH + G++L+ S+K+SLYVRALFDYDP  D+G+PS+GL F +GDI+HV NASDD+WWQAR++   G+E G+G++PS+ RWERK R++DRSV++        D++ +  R  K+          KS +D                  D   E   + ++SYE VQQ+ I YTRPVI+LGPLKDRIND+LISEFPDKFGSCVPHTTRPKR++EVD RDYHFV SRE ME+DIQNH FIEAGQYNDNLYGTS+ASV+EVA++GKHCILDVSGNAIKRLQ A+LFPIA+FI+P+SV  I  +N  +MT+EQ +K + R+ ++E +F +YFT++V+G   +D+Y  VK +I   S   IWVP  E
Sbjct:  357 EIELVKGNKGLGFSIAGGIGNQHIPGDNGIYVTK--------------VMEGGAAQVDGRLLVGDKLVAVRDAVKGEVNLENVTHEDAVTTLKTTQDRVVLVVAKPDSAFNAPASDTSYSPQLSTKASNAYPESIHSSNLALHHPPST---PRAVSQEDVSREVRTVILQKGGSGLGFNIVGGEDGEGIFISFILAGGPADLSGELRRGDQILSVNGVNLRNATHEEAAQTLKGTSSTVTMVVQYRPEEYNRFEAKIHDLKQQISHPVTGTLLRTSQKRSLYVRALFDYDPMKDDGLPSRGLAFHYGDILHVTNASDDEWWQARRVLNTGDEQGMGIVPSKRRWERKQRARDRSVKFQGHMPNIMDKQSTLDRKKKNFSFSRKFPFMKSKDDKSEDGSDQEPFMLCYTQEDANAEGNEENVLSYEPVQQMAINYTRPVIILGPLKDRINDDLISEFPDKFGSCVPHTTRPKREYEVDARDYHFVSSREQMEKDIQNHLFIEAGQYNDNLYGTSVASVREVADKGKHCILDVSGNAIKRLQVAQLFPIAIFIKPKSVESIMEMN-KRMTEEQAKKTFERSLKMEQEFGEYFTAVVQGDTPEDIYEQVKEVIKEQSGPTIWVPTKE 962          

HSP 2 Score: 120.168 bits (300), Expect = 3.679e-24
Identity = 85/231 (36.80%), Postives = 107/231 (46.32%), Query Frame = 0
Query:  162 YEYDEIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPSSPTIGQMHPLDSRTLQRSVSDEELRIPRDVLLHKTAAGLGFNIVGGEDGE------GIFISFILAGGPADVSGQIRRGDKILTV-----NAIDLSRATHEDAAIALKNAGSSVAL 381
            +EY+EIILERG  GLGFSIAGG DNPH G DT+IYITKLIPGGAAS D RLRV D   +  D  +                       H  AV ALKK  + V L V +                                   ++ L K   GLGF+I GG   +      GI+++ ++ GG A V G++  GDK++ V       ++L   THEDA   LK     V L
Sbjct:  257 WEYEEIILERGGAGLGFSIAGGTDNPHIGDDTAIYITKLIPGGAASADGRLRVNDSILSVNDVPVVD-------------------VPHASAVEALKKAGNTVKLCVRRRRQPRNMRLM-------------------------EIELVKGNKGLGFSIAGGIGNQHIPGDNGIYVTKVMEGGAAQVDGRLLVGDKLVAVRDAVKGEVNLENVTHEDAVTTLKTTQDRVVL 443          
BLAST of discs large 1 vs. nr
Match: gi|1284992695|ref|XP_023022564.1| (disks large 1 tumor suppressor protein isoform X5 [Leptinotarsa decemlineata])

HSP 1 Score: 636.336 bits (1640), Expect = 0.000e+0
Identity = 327/625 (52.32%), Postives = 427/625 (68.32%), Query Frame = 0
Query:  166 EIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPS-------SPTIG---------QMHPLDSRTLQ--------RSVSDEEL-RIPRDVLLHKTAAGLGFNIVGGEDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRLLYCPDEYEKFEAKIHSIKSH----VMAGSVLKMSEKKSLYVRALFDYDPSVDEGIPSKGLNFIFGDIIHVINASDDDWWQARKIDPLGNELGVGLIPSRNRWERKMRSKDRSVRW--------DREGSGKRMGKS----------KSSNDT-----------------DGEHENGLDTIISYELVQQIEIEYTRPVIVLGPLKDRINDELISEFPDKFGSCVPHTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQAARLFPIAVFIRPQSVSFIKHVNDDQMTKEQCEKIYARAKRLENDFMQYFTSIVEGSDFDDVYSNVKRLISIHSSTKIWVPANE 726
            EI L +G  GLGFSIAGG+ N H   D  IY+TK              VMDGGAA  D R+ VGD+LV V++   GE  L+N THE+AV  LK  +D+VVLVV+K D  + +       SP +           MH + S  L         R+VS E++ R  R ++LHK  +GLGFNIVGGEDGEGIFISFILAGGPAD  G++RRGD+I++VN ++L  ATHE+AA+ALK    +V + + Y P+EY +FEAKIH +K      V  G++L+ S+K+SLYVRALFDYDP  D+G+PS+GL F +GDI+HV NASDD+WWQAR++   G+E G+G++PS+ RWERK R++DRSV++        +++ +  R  K+          KS +D                  D   E G + ++SYE VQQ++I YTRPVI+LGPLKDRIND+LISEFPDKFGSCVPHTTR KR++EVDGRDYHFV SRE ME+DIQNH FIEAGQYNDNLYGTS+ASV+EVA++GKHCILDVSGNAIKRLQ A+L+PIA+FI+P+SV  I  +N  +M +EQ +K + RA ++E +F +YFT++V+G   +D+Y+ VK +I   S  KIWVP  E
Sbjct:  317 EIELVKGNKGLGFSIAGGIGNQHIPGDNGIYVTK--------------VMDGGAAQVDGRLLVGDKLVAVRDAVKGEVNLENVTHEDAVATLKTTQDRVVLVVAKPDITFNAPASDASYSPQLSTKASHGYADSMHSVHSSNLTLHHPPSTPRAVSAEDITRDVRSIVLHKGGSGLGFNIVGGEDGEGIFISFILAGGPADQCGELRRGDQIISVNGVNLRNATHEEAALALKGTNQTVNIVVQYRPEEYNRFEAKIHDLKQQMANPVTGGTLLRTSQKRSLYVRALFDYDPMKDDGLPSRGLAFHYGDILHVTNASDDEWWQARRVLNTGDEQGMGIVPSKRRWERKQRARDRSVKFQGHMPNILEKQSTLDRKKKNFSFSRKFPFMKSKDDKSEDGSDQEPFMLCYTQEDANAEGGEENVLSYEPVQQLQINYTRPVIILGPLKDRINDDLISEFPDKFGSCVPHTTRAKREYEVDGRDYHFVSSREQMEKDIQNHLFIEAGQYNDNLYGTSVASVREVADKGKHCILDVSGNAIKRLQVAQLYPIAIFIKPKSVESIMEMN-KRMNEEQAKKTFERAVKMEQEFGEYFTAVVQGDTPEDIYNEVKEVIEEQSGPKIWVPTKE 926          

HSP 2 Score: 123.635 bits (309), Expect = 2.664e-25
Identity = 88/238 (36.97%), Postives = 117/238 (49.16%), Query Frame = 0
Query:  162 YEYDEIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPSSPTIGQMHPLDSRTLQRSVSDEELRIPRDVLLHKTAAGLGFNIVGGEDGE------GIFISFILAGGPADVSGQIRRGDKILTV-----NAIDLSRATHEDAAIALKNAGSSVALRLLYCPD 388
            +EY+EIILERG  GLGFSIAGG DNPH G DT+IYITKLIPGGAAS              AD R+ V D +++V + P    V+D   H  AV ALKK  + V L + +                                   ++ L K   GLGF+I GG   +      GI+++ ++ GG A V G++  GDK++ V       ++L   THEDA   LK     V L ++  PD
Sbjct:  217 WEYEEIILERGGSGLGFSIAGGTDNPHIGDDTAIYITKLIPGGAAS--------------ADGRLLVNDSILSVNDVP----VID-VPHALAVDALKKAGNTVKLCIRRRRQPRNMRLM-------------------------EIELVKGNKGLGFSIAGGIGNQHIPGDNGIYVTKVMDGGAAQVDGRLLVGDKLVAVRDAVKGEVNLENVTHEDAVATLKTTQDRVVL-VVAKPD 409          

HSP 3 Score: 120.168 bits (300), Expect = 3.568e-24
Identity = 58/92 (63.04%), Postives = 71/92 (77.17%), Query Frame = 0
Query:    1 MPVCKAEAHRALELLEDYYARLDETDEKELKSAIERVIKIFKSRLFQALLDIQEFYELTLMDEGKSNDIKTTEALEMATRWELTNRPFAKGY 92
            MPV K EAHRALELLEDY+++L +  +K+L+ AIERVI+IFKSRLFQALLDIQEFYELTL+DE KS   KT E + +A +WE  + P    Y
Sbjct:    1 MPVRKQEAHRALELLEDYHSKLIKPQDKQLRLAIERVIRIFKSRLFQALLDIQEFYELTLLDENKSVQEKTAETIRIANKWEANDGPIIPPY 92          
BLAST of discs large 1 vs. nr
Match: gi|1183238578|ref|XP_020710840.1| (disks large 1 tumor suppressor protein isoform X9 [Athalia rosae])

HSP 1 Score: 636.336 bits (1640), Expect = 0.000e+0
Identity = 333/620 (53.71%), Postives = 431/620 (69.52%), Query Frame = 0
Query:  166 EIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPSSPTI-------------GQMHPLDSRTLQ-------------------RSVSDEEL-RIPRDVLLHKTAAGLGFNIVGGEDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRLLYCPDEYEKFEAKIHSIKSHV-----MAGSVLKMSEKKSLYVRALFDYDPSVDEGIPSKGLNFIFGDIIHVINASDDDWWQARKIDPLGNELGVGLIPSRNRWERKMRSKDRSVRW--------DREGSGKR------------MGKSKSSNDTDG-EHENGLDTIISYELVQQIEIEYTRPVIVLGPLKDRINDELISEFPDKFGSCVPHTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQAARLFPIAVFIRPQSVSFIKHVNDDQMTKEQCEKIYARAKRLENDFMQYFTSIVEGSDFDDVYSNVKRLISIHSSTKIWVPANE 726
            EI L +G  GLGFSIAGG+ N H   D  IY+TK              +MDGGAA  D R+ VGD+LV V+N   G+  L+N THEEAV  LK  +D+VVL+V+K +   P  P+              G +  L++ +L                    R+VS E++ R  R VLL+K  +GLGFNIVGGEDGEGIFISFILAGGPAD+SG++RRGD+IL+VN I+L  ATHE+AA ALK  G +V + + Y P++Y +FEAKIH +K  +     M G++++ S+KKSLYVRALFDYDP+ D+G+PS+GL F +G+I+HV NASDD+WWQAR++ P G E G+G+IPSR RWERK R++DRSV++        D++ +  R              KSK     DG + E   +T++SYE VQQ+ I+YTRPVI+LGPLKDRIND+LISEFPDKFGSCVPHTTR KR++EVDGRDYHFV SRE MERDIQNH FIEAGQYNDNLYGTS+ASV+EVAE+GKHCILDVSGNAIKRLQ A+L+PIA+FI+P+SV  +  +N  +MT+EQ +K Y RA ++E +F +YFT++V+G   +D+Y  VK +IS  S   IWVP+ +
Sbjct:  377 EIELIKGNKGLGFSIAGGIGNQHIPGDNGIYVTK--------------IMDGGAAQVDGRLIVGDKLVAVRNTLQGDKNLENVTHEEAVATLKATQDRVVLLVAKPEGVLPPPPSASELSLSPQPRKQNGSVSALENNSLAYSQESRHASSLALHTASTPRAVSQEDISREVRTVLLNKGTSGLGFNIVGGEDGEGIFISFILAGGPADLSGELRRGDQILSVNGINLRTATHEEAAAALKGTGQTVTIVVQYKPEDYNRFEAKIHDLKQQISQQNMMTGTLMRTSQKKSLYVRALFDYDPNKDDGLPSRGLAFKYGEILHVTNASDDEWWQARRVTPQGEEEGLGIIPSRRRWERKQRARDRSVKFQGHMPVILDKQSTLDRKKKNFSFSRKFPFMKSKDDKSEDGSDQERSEETVLSYEAVQQLAIQYTRPVIILGPLKDRINDDLISEFPDKFGSCVPHTTRSKREYEVDGRDYHFVGSREQMERDIQNHLFIEAGQYNDNLYGTSVASVREVAEKGKHCILDVSGNAIKRLQVAQLYPIAIFIKPKSVESVMEMN-KRMTEEQAKKTYERALKMEQEFGEYFTAVVQGDTPEDIYLKVKEVISEQSGPSIWVPSRD 981          

HSP 2 Score: 127.487 bits (319), Expect = 1.756e-26
Identity = 91/231 (39.39%), Postives = 119/231 (51.52%), Query Frame = 0
Query:  162 YEYDEIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPSSPTIGQMHPLDSRTLQRSVSDEELRIPRDVLLHKTAAGLGFNIVGGEDGE------GIFISFILAGGPADVSGQIRRGDKILTVNAI-----DLSRATHEDAAIALKNAGSSVAL 381
            +EY+EIILERG  GLGFSIAGG DNPH G+DT+IYITKLIPGGAAS D RLRV        D+ ++V D   +V + P          H  AV ALK+  + V L V +                      +RS S+  L    ++ L K   GLGF+I GG   +      GI+++ I+ GG A V G++  GDK++ V        +L   THE+A   LK     V L
Sbjct:  277 WEYEEIILERGGAGLGFSIAGGTDNPHIGNDTAIYITKLIPGGAASADGRLRV-------NDTILQVND--ASVVDVP----------HATAVDALKRAGNTVKLYVRR----------------------RRSASNTRL---LEIELIKGNKGLGFSIAGGIGNQHIPGDNGIYVTKIMDGGAAQVDGRLIVGDKLVAVRNTLQGDKNLENVTHEEAVATLKATQDRVVL 463          
BLAST of discs large 1 vs. nr
Match: gi|1008428396|ref|XP_015840482.1| (PREDICTED: disks large 1 tumor suppressor protein isoform X4 [Tribolium castaneum])

HSP 1 Score: 636.336 bits (1640), Expect = 0.000e+0
Identity = 329/628 (52.39%), Postives = 428/628 (68.15%), Query Frame = 0
Query:  166 EIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHY--PSSPT----------------------IGQMHPLDSRTLQRSVSDEEL-RIPRDVLLHKTAAGLGFNIVGGEDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRLLYCPDEYEKFEAKIHSIK---SHVMAGSVLKMSEKKSLYVRALFDYDPSVDEGIPSKGLNFIFGDIIHVINASDDDWWQARKIDPLGNELGVGLIPSRNRWERKMRSKDRSVRW--------DREGSGKRMGKS---------------KSSNDTDGEHENGL----------------DTIISYELVQQIEIEYTRPVIVLGPLKDRINDELISEFPDKFGSCVPHTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQAARLFPIAVFIRPQSVSFIKHVNDDQMTKEQCEKIYARAKRLENDFMQYFTSIVEGSDFDDVYSNVKRLISIHSSTKIWVPANE 726
            EI L +G  GLGFSIAGG+ N H   D  IY+TK              VM+GGAA  D R+ VGD+LV V++   GE  L+N THE+AVT LK  +D+VVLVV+K D+ +  P+S T                      +   HP  +    R+VS E++ R  R V+L K  +GLGFNIVGGEDGEGIFISFILAGGPAD+SG++RRGD+IL+VN ++L  ATHE+AA  LK   S+V + + Y P+EY +FEAKIH +K   SH + G++L+ S+K+SLYVRALFDYDP  D+G+PS+GL F +GDI+HV NASDD+WWQAR++   G+E G+G++PS+ RWERK R++DRSV++        D++ +  R  K+               KS + +D EH                    + ++SYE VQQ+ I YTRPVI+LGPLKDRIND+LISEFPDKFGSCVPHTTRPKR++EVD RDYHFV SRE ME+DIQNH FIEAGQYNDNLYGTS+ASV+EVA++GKHCILDVSGNAIKRLQ A+LFPIA+FI+P+SV  I  +N  +MT+EQ +K + R+ ++E +F +YFT++V+G   +D+Y  VK +I   S   IWVP  E
Sbjct:  357 EIELVKGNKGLGFSIAGGIGNQHIPGDNGIYVTK--------------VMEGGAAQVDGRLLVGDKLVAVRDAVKGEVNLENVTHEDAVTTLKTTQDRVVLVVAKPDSAFNAPASDTSYSPQLSTKASNAYPESIHSSNLALHHPPST---PRAVSQEDVSREVRTVILQKGGSGLGFNIVGGEDGEGIFISFILAGGPADLSGELRRGDQILSVNGVNLRNATHEEAAQTLKGTSSTVTMVVQYRPEEYNRFEAKIHDLKQQISHPVTGTLLRTSQKRSLYVRALFDYDPMKDDGLPSRGLAFHYGDILHVTNASDDEWWQARRVLNTGDEQGMGIVPSKRRWERKQRARDRSVKFQGHMPNIMDKQSTLDRKKKNFSFSRKFPFMKSKDDKSEDGSDQEHSPSATPNSANDNERNPSCNEENVLSYEPVQQMAINYTRPVIILGPLKDRINDDLISEFPDKFGSCVPHTTRPKREYEVDARDYHFVSSREQMEKDIQNHLFIEAGQYNDNLYGTSVASVREVADKGKHCILDVSGNAIKRLQVAQLFPIAIFIKPKSVESIMEMN-KRMTEEQAKKTFERSLKMEQEFGEYFTAVVQGDTPEDIYEQVKEVIKEQSGPTIWVPTKE 966          

HSP 2 Score: 120.168 bits (300), Expect = 3.445e-24
Identity = 85/231 (36.80%), Postives = 107/231 (46.32%), Query Frame = 0
Query:  162 YEYDEIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPSSPTIGQMHPLDSRTLQRSVSDEELRIPRDVLLHKTAAGLGFNIVGGEDGE------GIFISFILAGGPADVSGQIRRGDKILTV-----NAIDLSRATHEDAAIALKNAGSSVAL 381
            +EY+EIILERG  GLGFSIAGG DNPH G DT+IYITKLIPGGAAS D RLRV D   +  D  +                       H  AV ALKK  + V L V +                                   ++ L K   GLGF+I GG   +      GI+++ ++ GG A V G++  GDK++ V       ++L   THEDA   LK     V L
Sbjct:  257 WEYEEIILERGGAGLGFSIAGGTDNPHIGDDTAIYITKLIPGGAASADGRLRVNDSILSVNDVPVVD-------------------VPHASAVEALKKAGNTVKLCVRRRRQPRNMRLM-------------------------EIELVKGNKGLGFSIAGGIGNQHIPGDNGIYVTKVMEGGAAQVDGRLLVGDKLVAVRDAVKGEVNLENVTHEDAVTTLKTTQDRVVL 443          
BLAST of discs large 1 vs. nr
Match: gi|1070597704|ref|XP_018396091.1| (PREDICTED: disks large 1 tumor suppressor protein isoform X7 [Cyphomyrmex costatus])

HSP 1 Score: 635.18 bits (1637), Expect = 0.000e+0
Identity = 330/625 (52.80%), Postives = 425/625 (68.00%), Query Frame = 0
Query:  166 EIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSK--------------GDTHYPSSP--TIGQMHPLDSRTLQ---------------------RSVSDEEL-RIPRDVLLHKTAAGLGFNIVGGEDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRLLYCPDEYEKFEAKIHSIK-----SHVMAGSVLKMSEKKSLYVRALFDYDPSVDEGIPSKGLNFIFGDIIHVINASDDDWWQARKIDPLGNELGVGLIPSRNRWERKMRSKDRSVRW--------DREGSGKR------------MGKSKSSNDTDG-EHENGLDTIISYELVQQIEIEYTRPVIVLGPLKDRINDELISEFPDKFGSCVPHTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQAARLFPIAVFIRPQSVSFIKHVNDDQMTKEQCEKIYARAKRLENDFMQYFTSIVEGSDFDDVYSNVKRLISIHSSTKIWVPANE 726
            EI L +G  GLGFSIAGG+ N H   D  IY+TK              +MDGGAA  D R+ VGD+LV VKN   G+  L+N THEEAV  LK  +D+VVL+VSK               D    S P    G +  +++ T                       R+VS E++ R  R V+L+K + GLGFNIVGGEDGEGIFISFILAGGPAD+SG++RRGD+IL+VN I+L  ATHE+AA  LK    +V + + Y P++Y +FEAKI  +K      +VM G++++ S+KKSLYVRALFDYDP+ D+G+PS+GL F +G+I+HV NASDD+WWQAR++ P G E G+G+IPSR RWERK R++DRSV++        D++ +  R              KSK     DG + E   + ++SYE VQQ+ I+YTRPVIVLGPLKDRIND+LISEFPDKFGSCVPHTTR +R++EVDGRDYHFV SRE MERDIQNH FIEAGQYNDNLYGTS+ASV+EVAE+GKHCILDVSGNAIKRLQ A+L+PIA+FI+P+SV  +  +N  +MT+EQ +K Y RA ++E +F +YFT++V+G   +++Y  VK +IS  S   IWVP  +
Sbjct:  343 EIELIKGNKGLGFSIAGGIGNQHIPGDNGIYVTK--------------IMDGGAAQVDGRLVVGDKLVAVKNALQGDKNLENVTHEEAVAILKATQDRVVLLVSKTESGIIPPPPPPVATDNSLSSQPRKQNGSVSAMENNTAALPYSQESRHASSLALHGTGTPRAVSQEDVSREVRTVVLNKGSPGLGFNIVGGEDGEGIFISFILAGGPADLSGELRRGDQILSVNGINLRTATHEEAAAVLKGTSQTVTIVVQYKPEDYNRFEAKIQDLKQQISQQNVMTGTLMRTSQKKSLYVRALFDYDPNKDDGLPSRGLAFRYGEILHVTNASDDEWWQARRVTPQGEEEGLGIIPSRRRWERKQRARDRSVKFQGHMPVILDKQSTLDRKKKNFSFSRKFPFMKSKDDKSEDGSDQERSEENVLSYEAVQQLTIQYTRPVIVLGPLKDRINDDLISEFPDKFGSCVPHTTRSRREYEVDGRDYHFVASREQMERDIQNHLFIEAGQYNDNLYGTSVASVREVAEKGKHCILDVSGNAIKRLQVAQLYPIAIFIKPKSVESVMEMN-KRMTEEQAKKTYERALKMEQEFGEYFTAVVQGDTPEEIYVKVKEVISEQSGPNIWVPCRD 952          

HSP 2 Score: 119.783 bits (299), Expect = 4.818e-24
Identity = 88/231 (38.10%), Postives = 119/231 (51.52%), Query Frame = 0
Query:  162 YEYDEIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPSSPTIGQMHPLDSRTLQRSVSDEELRIPRDVLLHKTAAGLGFNIVGGEDGE------GIFISFILAGGPADVSGQIRRGDKILTV-NAI----DLSRATHEDAAIALKNAGSSVAL 381
            ++Y++IILERG  GLGFSIAGG DNPH G+DT+IYITKLIPGGAA+ D RLRV        D+ ++V D  V+V + P          H  AV ALK+  + V L +                         R     +L    ++ L K   GLGF+I GG   +      GI+++ I+ GG A V G++  GDK++ V NA+    +L   THE+A   LK     V L
Sbjct:  246 WDYEDIILERGGAGLGFSIAGGTDNPHYGNDTAIYITKLIPGGAAAADGRLRV-------NDTILQVND--VSVVDVP----------HAAAVDALKRAGNTVKLYI-------------------------RRRKHTQL---MEIELIKGNKGLGFSIAGGIGNQHIPGDNGIYVTKIMDGGAAQVDGRLVVGDKLVAVKNALQGDKNLENVTHEEAVAILKATQDRVVL 429          

HSP 3 Score: 116.316 bits (290), Expect = 5.200e-23
Identity = 59/97 (60.82%), Postives = 74/97 (76.29%), Query Frame = 0
Query:    6 AEAHRALELLEDYYARLDETDEKELKSAIERVIKIFKSRLFQALLDIQEFYELTLMDEGKSNDIKTTEALEMATRWELTNRP----FAKGYEGHLSS 98
            AEAHRALELLEDY+A+L    +K+L+ AIERVI+IFKSRLFQALLDIQEFYELTL+DE KS   KT E + +A +WE ++ P    FA+  +G  S+
Sbjct:   34 AEAHRALELLEDYHAKLTRPQDKQLRLAIERVIRIFKSRLFQALLDIQEFYELTLLDESKSVQQKTAETIRIADKWEASDGPITPTFAQNEDGPASA 130          
BLAST of discs large 1 vs. nr
Match: gi|1183238574|ref|XP_020710839.1| (disks large 1 tumor suppressor protein isoform X8 [Athalia rosae])

HSP 1 Score: 632.484 bits (1630), Expect = 0.000e+0
Identity = 335/633 (52.92%), Postives = 433/633 (68.40%), Query Frame = 0
Query:  166 EIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPSSPTI-------------GQMHPLDSRTLQ-------------------RSVSDEEL-RIPRDVLLHKTAAGLGFNIVGGEDGEGIFISFILAGGPADVSGQIRRGDKILTVNAIDLSRATHEDAAIALKNAGSSVALRLLYCPDEYEKFEAKIHSIKSHV-----MAGSVLKMSEKKSLYVRALFDYDPSVDEGIPSKGLNFIFGDIIHVINASDDDWWQARKIDPLGNELGVGLIPSRNRWERKMRSKDRSVRW--------DREGSGKR------------MGKSKSSNDTDG----------EHEN----GLDTIISYELVQQIEIEYTRPVIVLGPLKDRINDELISEFPDKFGSCVPHTTRPKRQFEVDGRDYHFVQSRETMERDIQNHKFIEAGQYNDNLYGTSIASVKEVAERGKHCILDVSGNAIKRLQAARLFPIAVFIRPQSVSFIKHVNDDQMTKEQCEKIYARAKRLENDFMQYFTSIVEGSDFDDVYSNVKRLISIHSSTKIWVPANE 726
            EI L +G  GLGFSIAGG+ N H   D  IY+TK              +MDGGAA  D R+ VGD+LV V+N   G+  L+N THEEAV  LK  +D+VVL+V+K +   P  P+              G +  L++ +L                    R+VS E++ R  R VLL+K  +GLGFNIVGGEDGEGIFISFILAGGPAD+SG++RRGD+IL+VN I+L  ATHE+AA ALK  G +V + + Y P++Y +FEAKIH +K  +     M G++++ S+KKSLYVRALFDYDP+ D+G+PS+GL F +G+I+HV NASDD+WWQAR++ P G E G+G+IPSR RWERK R++DRSV++        D++ +  R              KSK     DG          E+EN      +T++SYE VQQ+ I+YTRPVI+LGPLKDRIND+LISEFPDKFGSCVPHTTR KR++EVDGRDYHFV SRE MERDIQNH FIEAGQYNDNLYGTS+ASV+EVAE+GKHCILDVSGNAIKRLQ A+L+PIA+FI+P+SV  +  +N  +MT+EQ +K Y RA ++E +F +YFT++V+G   +D+Y  VK +IS  S   IWVP+ +
Sbjct:  377 EIELIKGNKGLGFSIAGGIGNQHIPGDNGIYVTK--------------IMDGGAAQVDGRLIVGDKLVAVRNTLQGDKNLENVTHEEAVATLKATQDRVVLLVAKPEGVLPPPPSASELSLSPQPRKQNGSVSALENNSLAYSQESRHASSLALHTASTPRAVSQEDISREVRTVLLNKGTSGLGFNIVGGEDGEGIFISFILAGGPADLSGELRRGDQILSVNGINLRTATHEEAAAALKGTGQTVTIVVQYKPEDYNRFEAKIHDLKQQISQQNMMTGTLMRTSQKKSLYVRALFDYDPNKDDGLPSRGLAFKYGEILHVTNASDDEWWQARRVTPQGEEEGLGIIPSRRRWERKQRARDRSVKFQGHMPVILDKQSTLDRKKKNFSFSRKFPFMKSKDDKSEDGSDQERSPTTPENENDPMRSEETVLSYEAVQQLAIQYTRPVIILGPLKDRINDDLISEFPDKFGSCVPHTTRSKREYEVDGRDYHFVGSREQMERDIQNHLFIEAGQYNDNLYGTSVASVREVAEKGKHCILDVSGNAIKRLQVAQLYPIAIFIKPKSVESVMEMN-KRMTEEQAKKTYERALKMEQEFGEYFTAVVQGDTPEDIYLKVKEVISEQSGPSIWVPSRD 994          

HSP 2 Score: 127.872 bits (320), Expect = 1.243e-26
Identity = 91/231 (39.39%), Postives = 119/231 (51.52%), Query Frame = 0
Query:  162 YEYDEIILERGTYGLGFSIAGGVDNPHAGSDTSIYITKLIPGGAASLDKRLRVMDGGAAAADSRIEVGDRLVTVKNFPGGEFVLDNCTHEEAVTALKKCKDKVVLVVSKGDTHYPSSPTIGQMHPLDSRTLQRSVSDEELRIPRDVLLHKTAAGLGFNIVGGEDGE------GIFISFILAGGPADVSGQIRRGDKILTVNAI-----DLSRATHEDAAIALKNAGSSVAL 381
            +EY+EIILERG  GLGFSIAGG DNPH G+DT+IYITKLIPGGAAS D RLRV        D+ ++V D   +V + P          H  AV ALK+  + V L V +                      +RS S+  L    ++ L K   GLGF+I GG   +      GI+++ I+ GG A V G++  GDK++ V        +L   THE+A   LK     V L
Sbjct:  277 WEYEEIILERGGAGLGFSIAGGTDNPHIGNDTAIYITKLIPGGAASADGRLRV-------NDTILQVND--ASVVDVP----------HATAVDALKRAGNTVKLYVRR----------------------RRSASNTRL---LEIELIKGNKGLGFSIAGGIGNQHIPGDNGIYVTKIMDGGAAQVDGRLIVGDKLVAVRNTLQGDKNLENVTHEEAVATLKATQDRVVL 463          
The following BLAST results are available for this feature:
BLAST of discs large 1 vs. L. salmonis genes
Analysis Date: 2018-04-19 (T. kinsejongensis vs L. Salmonis peptides)
Total hits: 17
Match NameE-valueIdentityDescription
EMLSAG000000009354.773e-15762.90supercontig:LSalAtl2s:LSalAtl2s1165:38108:40629:1 ... [more]
EMLSAG000000055865.040e-15749.01supercontig:LSalAtl2s:LSalAtl2s2:2091985:2095229:1... [more]
EMLSAG000000066674.555e-4028.70supercontig:LSalAtl2s:LSalAtl2s36:1323669:1338125:... [more]
EMLSAG000000014231.181e-3228.85supercontig:LSalAtl2s:LSalAtl2s1244:119229:120542:... [more]
EMLSAG000000010199.888e-2226.25supercontig:LSalAtl2s:LSalAtl2s116:953600:1003455:... [more]
EMLSAG000000009343.393e-2032.97supercontig:LSalAtl2s:LSalAtl2s1165:19602:26919:1 ... [more]
EMLSAG000000109365.565e-2030.00supercontig:LSalAtl2s:LSalAtl2s731:6608:7319:-1 ge... [more]
EMLSAG000000130502.116e-1930.63supercontig:LSalAtl2s:LSalAtl2s9:449519:463146:1 g... [more]
EMLSAG000000079262.965e-1930.14supercontig:LSalAtl2s:LSalAtl2s468:58567:60615:1 g... [more]
EMLSAG000000074926.092e-1628.92supercontig:LSalAtl2s:LSalAtl2s430:139689:146390:-... [more]

Pages

back to top
BLAST of discs large 1 vs. SwissProt
Analysis Date: 2018-04-19 (T. kingejongensis peptided Blastp vs. SwissProt)
Total hits: 25
Match NameE-valueIdentityDescription
gi|223590196|sp|Q12959.2|DLG1_HUMAN1.412e-5152.32RecName: Full=Disks large homolog 1; AltName: Full... [more]
gi|59797853|sp|Q811D0.1|DLG1_MOUSE6.802e-5651.38RecName: Full=Disks large homolog 1; AltName: Full... [more]
gi|2497505|sp|Q62696.1|DLG1_RAT3.779e-5351.63RecName: Full=Disks large homolog 1; AltName: Full... [more]
gi|68052302|sp|Q5PYH5.1|DLG1L_DANRE2.091e-2951.85RecName: Full=Discs large homolog 1-like protein; ... [more]
gi|123892312|sp|Q28C55.1|DLG1_XENTR3.045e-3348.34RecName: Full=Disks large homolog 1[more]
gi|68052060|sp|Q5PYH7.1|DLG2_DANRE6.817e-2948.92RecName: Full=Disks large homolog 2; AltName: Full... [more]
gi|218512007|sp|Q92796.2|DLG3_HUMAN2.778e-2450.00RecName: Full=Disks large homolog 3; AltName: Full... [more]
gi|2497507|sp|P70175.1|DLG3_MOUSE6.673e-2548.96RecName: Full=Disks large homolog 3; AltName: Full... [more]
gi|2497508|sp|Q62936.1|DLG3_RAT2.863e-2548.96RecName: Full=Disks large homolog 3; AltName: Full... [more]
gi|2497501|sp|Q62108.1|DLG4_MOUSE1.242e-2947.95RecName: Full=Disks large homolog 4; AltName: Full... [more]

Pages

back to top
BLAST of discs large 1 vs. nr
Analysis Date: 2018-05-15 (T. kingsejongensis proteins Blastp vs. NR)
Total hits: 25
Match NameE-valueIdentityDescription
gi|1325301983|ref|XP_023332535.1|1.743e-6260.91disks large 1 tumor suppressor protein-like [Euryt... [more]
gi|1227982859|ref|XP_021923054.1|3.468e-2652.56disks large 1 tumor suppressor protein isoform X3 ... [more]
gi|333033759|dbj|BAK23256.1|1.959e-5852.40discs large 1 [Gryllus bimaculatus][more]
gi|1284992693|ref|XP_023022488.1|3.149e-2552.24disks large 1 tumor suppressor protein isoform X4 ... [more]
gi|1008428398|ref|XP_015840483.1|3.679e-2452.72PREDICTED: disks large 1 tumor suppressor protein ... [more]
gi|1284992695|ref|XP_023022564.1|2.664e-2552.32disks large 1 tumor suppressor protein isoform X5 ... [more]
gi|1183238578|ref|XP_020710840.1|1.756e-2653.71disks large 1 tumor suppressor protein isoform X9 ... [more]
gi|1008428396|ref|XP_015840482.1|3.445e-2452.39PREDICTED: disks large 1 tumor suppressor protein ... [more]
gi|1070597704|ref|XP_018396091.1|4.818e-2452.80PREDICTED: disks large 1 tumor suppressor protein ... [more]
gi|1183238574|ref|XP_020710839.1|1.243e-2652.92disks large 1 tumor suppressor protein isoform X8 ... [more]

Pages

back to top
Alignments
The following features are aligned
Aligned FeatureFeature TypeAlignment Location
scaffold356_size197960supercontigscaffold356_size197960:169718..172156 -
Analyses
This gene is derived from or has results from the following analyses
Analysis NameDate Performed
maker2018-02-12 .496401
T. kinsejongensis vs L. Salmonis peptides2018-04-19
T. kingejongensis peptided Blastp vs. SwissProt2018-04-19
T. kingsejongensis proteins Blastp vs. NR2018-05-15
Properties
Property NameValue
Note-
Relationships

The following mRNA feature(s) are a part of this gene:

Feature NameUnique NameSpeciesType
maker-scaffold356_size197960-snap-gene-0.36-mRNA-1maker-scaffold356_size197960-snap-gene-0.36-mRNA-1Tigriopus kingsejongensismRNA


Sequences
The following sequences are available for this feature:

gene from alignment at scaffold356_size197960:169718..172156-

Legend: mRNA
Hold the cursor over a type above to highlight its positions in the sequence below.
>maker-scaffold356_size197960-snap-gene-0.36 ID=maker-scaffold356_size197960-snap-gene-0.36|Name=discs large 1|organism=Tigriopus kingsejongensis|type=gene|length=2439bp|location=Sequence derived from alignment at scaffold356_size197960:169718..172156- (Tigriopus kingsejongensis)
ATGCCCGTGTGTAAAGCGGAGGCCCATAGAGCCTTGGAGCTCCTAGAGGA CTACTACGCCCGCTTGGATGAGACGGACGAAAAGGAGCTCAAATCAGCCA TTGAGCGCGTGATTAAGATCTTCAAGTCCAGGCTCTTCCAGGCCTTGCTG GATATTCAAGAGTTCTACGAGTTGACGTTGATGGATGAAGGCAAGTCCAA CGACATCAAGACGACAGAAGCTTTGGAAATGGCCACCCGTTGGGAGCTCA CCAACCGACCTTTCGCCAAAGGCTACGAGGGACATCTCTCCAGCACGGCT CCTGGAGGATCCTCCCGCGGTGGTCCCACTCTGCCCCCTCAGTTTAAGGA GGAGCTCATGAGCAAGTTGCCCGAAATGCGCCATTACGACCCATCCTCCA GCTCGACCATGTCCGAGGCATCGGCCATGCCCGTGGCGAGCAATACTTCT ACGCCTGCCCCAGCCTCCAAGGTCGTCATACCCTACGAATACGACGAGAT CATCCTGGAGCGTGGGACCTACGGACTGGGCTTCTCCATAGCTGGTGGGG TGGACAATCCACATGCCGGCAGCGACACCTCCATTTATATTACCAAGCTC ATCCCCGGTGGGGCGGCCTCCTTGGACAAGCGCCTACGCGTGGGGGACAT CATCCTCAAGGTCAGCGACGTCAGTGTGGTCAATGTGTCCCACAGTGTGT CCGTGGAGGCGCTCAAGCGAGCGGGCAATCGAGTGGTGCTCTCCATCAAG CGCAAGCTCACCCAGATCAAAGACAACGAGGAGCTCCTCGAAGTTGAGCT CCTCAAAGGCAACAAAGGGCTGGGCTTTACCATAGCGGGCGGGATCGGCA ACCAGCACATCCCGGGCGACAACGGCATTTACGTGACCAAGGTCATGGAC GGCGGAGCGGCGGCCGCCGATTCCCGCATCGAGGTGGGCGATCGCCTCGT CACGGTCAAGAACTTCCCGGGTGGCGAGTTCGTTCTAGATAATTGCACCC ACGAGGAGGCGGTCACTGCCCTCAAGAAGTGCAAGGACAAGGTGGTCCTG GTGGTGAGCAAAGGCGACACCCACTACCCCTCGTCGCCCACGATCGGTCA AATGCACCCGTTGGACAGCCGGACCCTCCAGCGATCGGTCTCGGACGAGG AGCTCCGTATTCCCCGCGATGTCCTTCTCCACAAGACTGCCGCGGGTTTG GGCTTCAACATTGTGGGCGGAGAGGACGGCGAGGGGATCTTCATCTCGTT CATCCTGGCTGGAGGTCCGGCCGATGTGAGTGGACAGATCCGGAGGGGCG ACAAGATCCTCACTGTCAACGCCATCGACCTGAGTCGAGCCACCCACGAG GATGCCGCCATTGCCTTAAAGAACGCCGGCTCGAGTGTCGCCCTCCGACT GCTCTACTGTCCGGACGAATACGAAAAGTTCGAGGCCAAGATCCATTCCA TTAAGAGCCATGTCATGGCTGGAAGTGTGCTGAAAATGTCAGAAAAGAAG AGCTTGTACGTGCGAGCCCTCTTCGACTACGATCCGAGTGTGGACGAGGG CATCCCTTCCAAAGGCTTGAACTTCATCTTTGGCGACATCATCCATGTCA TCAATGCCTCGGACGACGACTGGTGGCAAGCCCGCAAGATCGATCCCCTG GGCAACGAGTTGGGCGTGGGTCTCATTCCGAGCCGGAACCGGTGGGAGCG GAAGATGCGGTCCAAGGACCGCAGCGTCCGATGGGACCGCGAGGGATCCG GCAAGCGGATGGGCAAGAGCAAGTCTTCCAACGACACCGATGGCGAGCAC GAAAACGGCCTGGACACGATCATCTCCTACGAGCTGGTCCAGCAAATCGA AATCGAGTACACCCGTCCCGTCATCGTGCTGGGCCCGCTCAAGGATCGGA TCAACGACGAGCTCATCTCCGAGTTCCCCGATAAGTTTGGATCCTGCGTC CCCCACACCACCCGCCCCAAGCGCCAGTTCGAGGTCGACGGACGAGATTA CCACTTTGTCCAGTCTCGCGAGACCATGGAGCGGGACATCCAGAACCACA AGTTCATCGAGGCCGGACAGTACAACGACAACCTCTACGGCACCTCCATC GCCTCCGTGAAGGAGGTGGCGGAGCGGGGCAAGCACTGCATCCTGGACGT GAGTGGGAACGCCATCAAGCGCCTCCAGGCTGCCCGCCTCTTCCCCATTG CCGTCTTCATCCGGCCTCAGAGCGTCTCCTTCATCAAGCATGTCAATGAT GATCAGATGACCAAAGAGCAGTGTGAGAAGATCTACGCCCGGGCGAAGCG TCTGGAAAATGACTTCATGCAATACTTTACATCCATCGTGGAGGGTAGTG ATTTCGATGATGTCTATAGCAATGTGAAGCGACTCATTAGTATTCATTCG TCGACCAAGATCTGGGTTCCGGCCAATGAAATGTTCTAA
back to top
Synonyms
The feature 'discs large 1' has the following synonyms
Synonym
Tk00538
Add to Basket