IKKbeta, maker-scaffold168_size293125-snap-gene-1.59 (gene) Tigriopus kingsejongensis
Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of IKKbeta vs. L. salmonis genes
Match: EMLSAG00000010753 (supercontig:LSalAtl2s:LSalAtl2s712:509674:515656:1 gene:EMLSAG00000010753 transcript:EMLSAT00000010753 description:"snap_masked-LSalAtl2s712-processed-gene-5.30") HSP 1 Score: 486.878 bits (1252), Expect = 2.238e-158 Identity = 275/664 (41.42%), Postives = 399/664 (60.09%), Query Frame = 0 Query: 98 YVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEED--LPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRNEAG-EIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGMVGEIQAIPK------DRPEDMQMFVKKSLQGLEDLRQI-PLEGR-KEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETLAKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQ 750 ++ + Q SG FG+V VW H+++ LA KKCR G LS REQW EV IL +L HPNV+KS P D EED LPL+ ME+CSGGDLR LN + GL + +VLAI DL SALG+LHNRRIIHRDLKPENVV+ R IYKLIDLGYAK+L QSSLA + VGTLQY+APE ++ +YTKSVDYWSLG ++HEI+TG RPFLP+ PG+WME VE K + IC+ + D + + F F EN++S +L D WL+SLLEW+ RG+NE EI +F DL IL+ R+++V +D NK+D+++ + L +E+ I Q+LL NG +L E L +P +Y + + +KI +P ++S LK+P+++V+ ++ IY+H Y+ QE + ++LI+ LL +K LN ++Q + + E+A+SK++LF+ESL +D EKY+EQ + ITSA+++++W++ E +L ++ +Q+V E+ + EI+ + K D D++ F KSL E L++ P GR E V+++A CLK+RD L+ +F + + + ++ L++F++ VSK QRKRQSD+WKLL+AALQ Sbjct: 7 WILENQSRSGGFGIVSVWVHKENKFRLAXKKCRLGKS--LSTNLREQWINEVAILGQLNHPNVIKSFPPPSDFKDKEEDSSLPLLFMEYCSGGDLRATLNTCENATGLQEVQVLAIISDLTSALGYLHNRRIIHRDLKPENVVIHIEKGRVIYKLIDLGYAKKLDQSSLAQTIVGTLQYLAPEFYMGNKYTKSVDYWSLGLITHEIVTGVRPFLPDYPPGKWMEVVENKNRETICIPELND-ERVEF----FLENNISESLQRDLAQWLQSLLEWDANLRGKNEVSEEITVFSDLNSILNCSRIKIVFLDNSLNKMDFVVENESSVDSLCEIIEKRVHIPKMCQILLTRNGNRLLCLEPFLKEKELGQPLCATVYVTDTRIITDIKEKISSYGFIIPDAVKSALKSPKEKVDFKTKRRIYAHGYYLLRQEEANHENSVVGTRILIVHLLNELKILNNSSQGLLKLFEKAVSKFDLFKESLNYDIEKYKEQATRRQRITSAKIYDSWSKPEPNLE---KQLKYIQQDVASFEKEIININQEIRNLQKSSSFKVDSCPDLKEFCAKSLTLCESLKKFSPSNGRPSESSNVVEMAXLXXICLKRRDEILRKHFTLLNQILIHVNAISSLMPKIEVSKNQLEIFLMAVSKSQRKRQSDVWKLLSAALQ 660
BLAST of IKKbeta vs. L. salmonis genes
Match: EMLSAG00000010271 (supercontig:LSalAtl2s:LSalAtl2s680:142787:148655:-1 gene:EMLSAG00000010271 transcript:EMLSAT00000010271 description:"maker-LSalAtl2s680-augustus-gene-1.23") HSP 1 Score: 112.079 bits (279), Expect = 2.317e-25 Identity = 97/372 (26.08%), Postives = 173/372 (46.51%), Query Frame = 0 Query: 96 GEYV-CQTQ-LGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDL----PLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVV-LQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELF--------LSQEYTKSVDYWSLGFLSHEIMTGRRPFLP---NLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRNEAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKD-LQTWLERDTGIHVGHQLLLMPNGQEI 448 YV C T LG G+ G V ++ +G+ +A+K + + + +E +E ++LQ+++H N+VK LL +EE+ ++ ME C+GG L +L+ P + GL + E L + L++ + L + ++HRDLKP N++ +YKL D G A+EL +S GT +Y+ P+++ + + + +VD WS+G + + TG PF P + KK+ I Q + I + L LSA + + L LLE P++R E F + IL + ++ + +++ Y+ R T+G D +T L T I + ++++ E+ Sbjct: 8 ANYVWCTTSVLGKGATGAVFQGVNKHNGETVAVKTFNQLSHM----RPQEVQMREFEVLQKVKHENIVK-------LLAIEEEQEGRGKVIVMELCTGGSLFNLLDDPENSYGLHEDEWLXVLSHLSAGMNHLRDNNLVHRDLKPGNIMKFIKDDGNIVYKLTDFGAARELEDDQQFVSLYGTEEYLHPDMYERAVLRKTVGKTFGATVDLWSIGVTLYHVATGNLPFRPFGGRRNKETMYHITTKKSSGVISGVQTSENGPIQWSRELPNSCLLSAGIKKHITPLLAGLLEVNPQKRWTFER----FFSQVTWILDKKKLHIYFMNKLTPHRIYLDR--TEGLDTFKTILSEQTEISPDNDMIILFGENEL 362 HSP 2 Score: 93.9745 bits (232), Expect = 8.908e-20 Identity = 58/171 (33.92%), Postives = 97/171 (56.73%), Query Frame = 0 Query: 148 EVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWM 318 EV ++++LEHPN+V + DL +++L + M++ +GG L ++ +H L + ++ AI+ ++ S + +LHN +IHRD+K +NV+L + K+ D G+ + + +F GT ++APE+ Q Y KSVD WSLG L E M R P + +P Q M Sbjct: 1056 EVQVMRKLEHPNLVAFL----DLFLTDKEL-WVVMDYMNGGPLTDVV---LHTI-LNEPQMSAISKEVLSGINYLHNHELIHRDIKSDNVLLSV---KGDVKITDFGFTANVSGDRMRKTFAGTPYWMAPEVVKKQTYGKSVDIWSLGILVIE-MVDRHPPYMDETPLQAM 1213
BLAST of IKKbeta vs. L. salmonis genes
Match: EMLSAG00000008721 (supercontig:LSalAtl2s:LSalAtl2s541:438808:485939:-1 gene:EMLSAG00000008721 transcript:EMLSAT00000008721 description:"maker-LSalAtl2s541-augustus-gene-3.15") HSP 1 Score: 112.464 bits (280), Expect = 2.452e-25 Identity = 69/211 (32.70%), Postives = 109/211 (51.66%), Query Frame = 0 Query: 98 YVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPF 308 Y ++G+G+FGVVH R K+GQ+ A K + + R+E+DI+ L H ++ D EE++ ++ EF SGG+L + + + + + EV+ + + F+H R IIH D+KPENV+ Q T K T KLID G A +L + L GT ++ APE+ + D WS+G LS+ +++G PF Sbjct: 8428 YDILEEIGTGAFGVVHRCRESKTGQVYAAKFIPISHAM-----EKALIRKEIDIMNHLHHNKLINLH----DAYEDEEEM-VLIFEFLSGGELFEKITSEGYT--MSEAEVINYMRQICEGVKFMHERNIIHLDIKPENVMCQ-TSKSTNVKLIDFGLATKLDPNELVKISTGTAEFAAPEIVEREPVGFYTDMWSIGVLSYVLLSGLSPF 8625
BLAST of IKKbeta vs. L. salmonis genes
Match: EMLSAG00000003715 (supercontig:LSalAtl2s:LSalAtl2s1:3290800:3325247:1 gene:EMLSAG00000003715 transcript:EMLSAT00000003715 description:"maker-LSalAtl2s1-augustus-gene-33.19") HSP 1 Score: 107.071 bits (266), Expect = 1.829e-24 Identity = 72/210 (34.29%), Postives = 110/210 (52.38%), Query Frame = 0 Query: 104 LGSGSFGVVHVWRHQKSGQILALK---KCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLP--LMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPF 308 LGSG FG+V+ H+++G+ +A+K K RF + K + EV ILQ + HP VV +L R+ E L + ME G D+ +M+ H L + + + AL LH++ I+H DLKPENV+L KL D G+A+ +G+ S VGT Y+APE+ ++ Y +S+D WS G + + ++G PF Sbjct: 198 LGSGQFGIVYGGVHRQNGEAVAVKVIDKMRFPS------KQEAALKNEVSILQNIHHPGVV-------NLERMFETLERIYVVMEKLKG-DMLEMILSSEHG-RLSERVTKFVVTQILVALKHLHSKNIVHCDLKPENVLLSSNSDFPQVKLCDFGFARIIGEKGFRKSVVGTPAYLAPEVLRNKGYNRSLDMWSTGVIIYVSLSGTFPF 392
BLAST of IKKbeta vs. L. salmonis genes
Match: EMLSAG00000011184 (supercontig:LSalAtl2s:LSalAtl2s760:424402:425388:1 gene:EMLSAG00000011184 transcript:EMLSAT00000011184 description:"augustus_masked-LSalAtl2s760-processed-gene-3.6") HSP 1 Score: 103.219 bits (256), Expect = 4.014e-24 Identity = 71/217 (32.72%), Postives = 115/217 (53.00%), Query Frame = 0 Query: 95 LGEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKML-NMPVHCCGLPQGEVLA--ITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPF 308 L ++ LG G FG V++ R +KS I+ALK F + + Q R+E++I L HP++++ D R+ + +EF S G+L K+L N P+ E LA ++ AL +LH++++IHRD+KPEN++L + K+ D G++ SS + GTL Y++PE+ + + + VD WSLG L E + G+ PF Sbjct: 50 LNDFDIGRPLGKGKFGNVYLAREKKSKFIVALK-VMFKNQLKKANVE-HQLRREIEIQXHLRHPHILRLYGYFYDETRV-----YLILEFASKGELYKLLKNEPLKRFE----ETLAARYIYQMSGALDYLHSKKVIHRDIKPENLLLD---SKGNLKIADFGWSVH-APSSRRGTMCGTLDYLSPEMIEGRSHDEKVDLWSLGILCFEFLVGKPPF 251
BLAST of IKKbeta vs. L. salmonis genes
Match: EMLSAG00000009407 (supercontig:LSalAtl2s:LSalAtl2s5:303399:304469:-1 gene:EMLSAG00000009407 transcript:EMLSAT00000009407 description:"augustus-LSalAtl2s5-processed-gene-3.1") HSP 1 Score: 102.449 bits (254), Expect = 1.079e-23 Identity = 75/243 (30.86%), Postives = 119/243 (48.97%), Query Frame = 0 Query: 94 RLGEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPG----------QWMEQVEKKTK 326 RL ++ + +G+G+F V + +H+ + ALK V L K E + E +IL L HP +V + KD L M + SGG+L L +P L ++ AL +LH++ I++RDLKPEN++L + K+ D G+AK + + L GT +Y+APE+ S+ + ++VD+WSLG L +E++ G PF + G W Q+E TK Sbjct: 43 RLEDFELRETIGTGTFARVCLVKHKFTHAYYALKILSIKDVVRL--KQVEHVKNETNILSELRHPYIVNLVWKYKDPKFL-----YMVFPYISGGELFSYLRT-AGRFNVPTS--LFYISEIVCALEYLHSQSIVYRDLKPENLLLD---RDGHLKITDFGFAKRISDRTWTL--CGTPEYLAPEIIQSKGHNRAVDWWSLGILIYEMLAGYPPFFDDNPFGIYEKILGGKIDWPRQMEPVTK 270
BLAST of IKKbeta vs. L. salmonis genes
Match: EMLSAG00000006879 (supercontig:LSalAtl2s:LSalAtl2s389:561753:579552:-1 gene:EMLSAG00000006879 transcript:EMLSAT00000006879 description:"maker-LSalAtl2s389-snap-gene-5.36") HSP 1 Score: 102.064 bits (253), Expect = 1.970e-22 Identity = 69/215 (32.09%), Postives = 114/215 (53.02%), Query Frame = 0 Query: 95 LGEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYT-KSVDYWSLGFLSHEIMTGRRPF 308 +G+Y +G G+F V + RH +G+ +A+K L+ ++ +EV I++ L+HPN+VK V + E+ L L+ ME+ SGG++ L V + + E A + SA+ + H ++IIHRDLK EN++L K+ D G++ E + +F G+ Y APELF ++Y VD WSLG + + +++G PF Sbjct: 116 IGKYRLLKTIGKGNFAKVKLARHTATGKEVAIKII---DKTQLNPGSLQKLFREVRIMKTLDHPNIVKLFQV----IETEKTLYLV-MEYASGGEVFDYL---VLHGRMKEKEARAKFRQIVSAVQYCHQKKIIHRDLKAENLLLD---SEMNIKIADFGFSNEFIPGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPF 316
BLAST of IKKbeta vs. L. salmonis genes
Match: EMLSAG00000004239 (supercontig:LSalAtl2s:LSalAtl2s222:1379053:1391929:1 gene:EMLSAG00000004239 transcript:EMLSAT00000004239 description:"maker-LSalAtl2s222-augustus-gene-13.20") HSP 1 Score: 101.679 bits (252), Expect = 2.277e-22 Identity = 73/208 (35.10%), Postives = 113/208 (54.33%), Query Frame = 0 Query: 104 LGSGSFGVVHVWRH---QKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPF 308 LG GSFG V + R + SG + A+K + T L + R + ++E DIL +EHP +VK + E L L+ ++F GGDL L+ + + +V +LA AL LH+ II+RDLKPEN++L + D G +KE + A SF GT++Y+APE+ + ++ + D+WS G L +E++TG+ PF Sbjct: 88 LGQGSFGKVFLVRKIEGKDSGTLYAMKVLKKAT---LRFRDRVRTKKERDILAEIEHPFMVKLYYA----FQTEGKLYLI-LDFLRGGDLFTRLSKEIM---FTEEDVKFYLAELALALIHLHSLGIIYRDLKPENLLLDSNGHIAV---TDFGLSKETIEDK-AYSFCGTVEYMAPEIVNRKGHSFAADWWSFGILMYEMLTGQLPF 280 HSP 2 Score: 90.8929 bits (224), Expect = 5.395e-19 Identity = 67/233 (28.76%), Postives = 113/233 (48.50%), Query Frame = 0 Query: 97 EYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRL-EHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDL-RKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTH-KRTIYKLIDLGYAKEL-GQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFL--PNLSPGQWMEQVEK 323 EY + +G GS+ H+ + A+K + + R+ EV+IL R +HPN++ V +D +D + E+ GG+L K+L + + E +I L SA+ +LH ++HRDLKP N++ ++ D G+AK+L + L ++ T Y+APE+ Q Y + D WSLG L H +++G+ PF PN S + ++E+ Sbjct: 436 EYEVKELIGVGSYSECKRCIHKATNVEYAMK--------VIDKSKRDCNSDEVEILLRYGQHPNIISLKDVFED-----KDFAYLIFEYMRGGELLDKILQQEI----FSEREARSIMERLTSAVHYLHQNGVVHRDLKPANILYADKFGDPNTLRICDFGFAKQLRADNGLLMTPCYTANYVAPEVLKQQGYDAACDVWSLGVLLHIMLSGKAPFANGPNDSMEVILSRIEE 651
BLAST of IKKbeta vs. L. salmonis genes
Match: EMLSAG00000005433 (supercontig:LSalAtl2s:LSalAtl2s292:565959:573639:1 gene:EMLSAG00000005433 transcript:EMLSAT00000005433 description:"maker-LSalAtl2s292-augustus-gene-5.11") HSP 1 Score: 95.1301 bits (235), Expect = 1.788e-21 Identity = 65/217 (29.95%), Postives = 110/217 (50.69%), Query Frame = 0 Query: 94 RLGEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGL-PQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLAL-SFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPF 308 +L + + ++G G F VV+ + + + +ALKK + + K R +E+ +LQ+L+HPNVV+ ++ +E + + +E GDL M+ L P+ + + SAL ++H++RI+HRD+KP NV + + KL DLG + +++A S VGT Y++PE + Y D WSLG L +E+ PF Sbjct: 18 KLENFNVEKRIGKGQFSVVYRAKCKVDKRTVALKKVQILE--MMDSKARVDCVKEILLLQQLDHPNVVRYLAS-----FIENNELNIVLELADAGDLSWMIKYFKKSRKLLPEKTIWKYFVQICSALDYMHSKRIMHRDIKPANVFITANGEA---KLGDLGLGRFFSSNTMAAHSLVGTPYYMSPERIHEEGYNFKSDIWSLGCLLYEMAALHSPF 224
BLAST of IKKbeta vs. L. salmonis genes
Match: EMLSAG00000012530 (supercontig:LSalAtl2s:LSalAtl2s922:67995:142257:1 gene:EMLSAG00000012530 transcript:EMLSAT00000012530 description:"maker-LSalAtl2s922-augustus-gene-1.7") HSP 1 Score: 95.5153 bits (236), Expect = 1.475e-20 Identity = 68/210 (32.38%), Postives = 104/210 (49.52%), Query Frame = 0 Query: 104 LGSGSFGVVHVWR-----HQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPF 308 LG G FG V + + ++S + +KK + + + ++ E +I++ + +VK KD L M ME C GG+L +L T + A +LH+R II+RDLKPEN++L T KL+D G+AK+L +F GT +Y+APE+ L++ + S DYWSLG L E++TG PF Sbjct: 356 LGVGGFGRVELVQIAGDPKKRSFALKQMKKYQI-----VETRQQQHIMSEKEIMEESDCHFIVKLFKTFKDRKYL-----YMLMESCLGGELWTILR---DRGNFDDSTTRFYTACVIEAFDYLHSRGIIYRDLKPENLLLDTTG---YVKLVDFGFAKKLQVGRKTWTFCGTPEYVAPEVILNKGHDISADYWSLGVLMFELLTGTPPF 549
BLAST of IKKbeta vs. SwissProt
Match: gi|14285495|sp|Q9QY78.1|IKKB_RAT (RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit beta; Short=I-kappa-B-kinase beta; Short=IKK-B; Short=IKK-beta; Short=IkBKB; AltName: Full=I-kappa-B kinase 2; Short=IKK2; AltName: Full=Nuclear factor NF-kappa-B inhibitor kinase beta; Short=NFKBIKB) HSP 1 Score: 329.717 bits (844), Expect = 5.117e-100 Identity = 246/747 (32.93%), Postives = 382/747 (51.14%), Query Frame = 0 Query: 91 PGTRLGEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLE-EDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRN-EAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFS--------TLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFF--NDIRSKRQEV----NDILGEVNGMVGEIQAIPKDRPEDMQMFVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFN------KKETLAKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQQKQKGDNG-----------RSGNHQSVSSSPMASIPMPQHQGDEASMILYAENQALRAQLQEYMK 804 P G + + +LG+G FG V W +Q +G+ +A+K+CR LS K+R++W E+ I++RL HPNVV + VP+ + L DLPL+ ME+C GGDLR+ LN +CCGL +G +L + D+ASAL +LH RIIHRDLKPEN+VLQ KR I+K+IDLGYAKEL Q SL SFVGTLQY+APEL Q+YT +VDYWS G L+ E +TG RPFLPN P QW +V +K++ DI V + + FP N+L++ LAE E WL+ +L W+P++RG + + G G F+ L +IL+ V ++ + G Y + E + L+T + DTGI Q LL G +LP++ S TL+ +L ++ S M+ + + P+++ L+ P++ ++ + ++ + Q + ++ LL L+ +A ++ +K + F+ S+ D EKY+EQ + ITS ++ AW + E+ + ND++ + + DI+ +G Q D E+ ++ + LR+ P + R E D+ Q+MVR L Q ++ + K + K +L L +V + N D V + Q KRQ +LW LL A + + +G G+ S SS S+P D+ S L AE AL ++L+ ++ Sbjct: 8 PTQTCGAWEMKERLGTGGFGNVIRWHNQVTGEQIAIKQCRQE----LSPKNRDRWCLEIQIMRRLNHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLRRYLNQFENCCGLREGAILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEKRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVDIVVSEDLNGTVKFSSSSPFP-NNLNSVLAERLEKWLQLMLTWQPRQRGVDPQYGPNGCFRALDDILNLKLVHILNM-VTGTIHTYPVMEDESLQSLKTRIREDTGILETDQELLQEAGLVLLPDKPATQCISDSKTNEGLTLDMDLVFLFDNSK-----MSYETQITPRPQPESVSCVLQEPKRNLSFFQMRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMNLLRNNSCLSKMKNAMASTAQQLKAKLDFFKTSIQIDLEKYREQT--EFGITSDKLLLAWREMEQAVEQCGRENDVKVLVERMMALQTDIVDLQRSPMGRKQGGTLDDLEE------QARELYRRLREKPRDQRTEGDS-----QDMVRLLLQAIQSFEKKVRVIYSQLSKTVVCKQKALELLPKVEEVVRLMNED--EKTVVRLQEKRQKELWNLLKIACSKVRGPVSGSPDSMNVSRLSHPGHLMSQPSSACDSLP----DSDKKSEELVAEAHALCSRLESALQ 724
BLAST of IKKbeta vs. SwissProt
Match: gi|14285499|sp|O88351.1|IKKB_MOUSE (RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit beta; Short=I-kappa-B-kinase beta; Short=IKK-B; Short=IKK-beta; Short=IkBKB; AltName: Full=I-kappa-B kinase 2; Short=IKK2; AltName: Full=Nuclear factor NF-kappa-B inhibitor kinase beta; Short=NFKBIKB) HSP 1 Score: 329.717 bits (844), Expect = 6.436e-100 Identity = 248/740 (33.51%), Postives = 378/740 (51.08%), Query Frame = 0 Query: 91 PGTRLGEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLE-EDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTD-EIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRN-EAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRVKLT---MPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDL------NDFFNDIRSKRQEVNDILGEVNGMVGEIQAIPKDRPEDMQMFVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFN------KKETLAKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQQKQKGDNGRSGNHQSVS--SSPMASIPMPQH------QGDEASMILYAENQALRAQLQEYMK 804 P G + + +LG+G FG V W +Q +G+ +A+K+CR LS K+R +W E+ I++RL HPNVV + VP+ + L DLPL+ ME+C GGDLR+ LN +CCGL +G VL + D+ASAL +LH RIIHRDLKPEN+VLQ KR I+K+IDLGYAKEL Q SL SFVGTLQY+APEL Q+YT +VDYWS G L+ E +TG RPFLPN P QW +V +K++ DI V ED + + F L N+L++ LAE E WL+ +L W P++RG + + G G F+ L +IL+ V V+ + G Y + E + L+T ++ +TGI Q LL G +LP++ S + N + + L + ++T P+++ L+ P++ ++ + ++ + Q + ++ LL L+ +A ++ +K + F+ S+ D EKY+EQ + ITS ++ AW + E+ + ND + + DI+ +G Q D E+ ++ + LR+ P + R E D+ Q MVR L Q ++ + K + K +L L +V + N D V + Q KRQ +LW LL A K +G S + +VS S P + P + D+ S L AE AL ++L+ ++ Sbjct: 8 PTQTCGAWEMKERLGTGGFGNVIRWHNQATGEQIAIKQCRQE----LSPKNRNRWCLEIQIMRRLNHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLRRYLNQFENCCGLREGAVLTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEKRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVDIVVS--EDLNGAVKFSSSLPFPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPQYGPNGCFRALDDILNLKLVHVLNM-VTGTVHTYPVTEDESLQSLKTRIQENTGILETDQELLQKAGLVLLPDKPATQCISDSKTNEGLTLDMDLVFLLDNSKINYETQITPRPPPESVSCILQEPKRNLSFFQLRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMSLLRNNSCLSKMKNAMASTAQQLKAKLDFFKTSIQIDLEKYKEQT--EFGITSDKLLLAWREMEQAVEQCGRENDVKHLVERMMALQTDIVDLQRSPMGRKQGGTLDDLEE------QARELYRKLREKPRDQRTEGDS-----QEMVRLLLQAIQSFEKKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNEDERT--VVRLQEKRQKELWNLLKIAC-SKVRGPVSGSPDSMNVSRLSHPGQLMSQPSSACDSLPESDKKSEELVAEAHALCSRLESALQ 724
BLAST of IKKbeta vs. SwissProt
Match: gi|14285497|sp|O14920.1|IKKB_HUMAN (RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit beta; Short=I-kappa-B-kinase beta; Short=IKK-B; Short=IKK-beta; Short=IkBKB; AltName: Full=I-kappa-B kinase 2; Short=IKK2; AltName: Full=Nuclear factor NF-kappa-B inhibitor kinase beta; Short=NFKBIKB) HSP 1 Score: 328.176 bits (840), Expect = 1.877e-99 Identity = 237/721 (32.87%), Postives = 373/721 (51.73%), Query Frame = 0 Query: 96 GEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLE-EDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTD-EIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRNEA-GEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFS--------TLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGM---VGEIQAIPKDRPEDMQM--FVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFN------KKETLAKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQQKQKGDNG-----------RSGNHQSVSSSPMASIPMPQHQGDE 783 G + + +LG+G FG V W +Q++G+ +A+K+CR LS ++RE+W E+ I++RL HPNVV + VP+ + L DLPL+ ME+C GGDLRK LN +CCGL +G +L + D+ASAL +LH RIIHRDLKPEN+VLQ +R I+K+IDLGYAKEL Q SL SFVGTLQY+APEL Q+YT +VDYWS G L+ E +TG RPFLPN P QW +V +K++ DI V ED + + F L N+L++ LAE E WL+ +L W P++RG + G G FK L +IL+ V ++ + G Y + E + L+ +++DTGI Q LL G ++P++ S TL+ +L ++ S +T T + P+++ L+ P++ + + ++ + Q + ++ LL L+ +A ++ +K + F+ S+ D EKY EQ + ITS ++ AW + E+ + ++ + EV ++ + + + ++Q P R + + +++ + LR+ P + R E D +Q MVR L Q ++ + K + K +L L +V + N D V + Q KRQ +LW LL A + + +G + G S S+ S+P P + +E Sbjct: 13 GAWEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQE----LSPRNRERWCLEIQIMRRLTHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREGAILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEQRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVDIVVS--EDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPTYGPNGCFKALDDILNLKLVHILNM-VTGTIHTYPVTEDESLQSLKARIQQDTGIPEEDQELLQEAGLALIPDKPATQCISDGKLNEGHTLDMDLVFLFDNSKITYETQISPRPQ-----PESVSCILQEPKRNLAFFQLRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMNLLRNNSCLSKMKNSMASMSQQLKAKLDFFKTSIQIDLEKYSEQT--EFGITSDKLLLAWREMEQAV-----ELCGRENEVKLLVERMMALQTDIVDLQRSPMGRKQGGTLDDLEEQARELYRRLREKPRDQRTEGD-----SQEMVRLLLQAIQSFEKKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNED--EKTVVRLQEKRQKELWNLLKIACSKVRGPVSGSPDSMNASRLSQPGQLMSQPSTASNSLPEPAKKSEE 707
BLAST of IKKbeta vs. SwissProt
Match: gi|75057117|sp|Q95KV0.1|IKKB_BOVIN (RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit beta; Short=I-kappa-B-kinase beta; Short=IKK-B; Short=IKK-beta; Short=IkBKB; AltName: Full=I-kappa-B kinase 2; Short=IKK2; AltName: Full=Nuclear factor NF-kappa-B inhibitor kinase beta; Short=NFKBIKB) HSP 1 Score: 325.479 bits (833), Expect = 1.994e-98 Identity = 246/754 (32.63%), Postives = 386/754 (51.19%), Query Frame = 0 Query: 91 PGTRLGEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLE-EDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTD-EIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRNEA-GEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFS--------TLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGM---VGEIQAIPKDRPEDMQM--FVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFN------KKETLAKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQQKQKGDNGRSGNHQSVSSSPMA----------SIPMPQHQGDEASMILYAENQALRAQ----LQEYMKIQYQ 808 P G + + +LG+G FG V W +Q++G+ +A+K+CR LS ++RE+W E+ I++RL HPNVV + VP+ + L DLPL+ ME+C GGDLRK LN +CCGL +G +L + D+ASAL +LH RIIHRDLKPEN+VLQ +R I+K+IDLGYAKEL Q SL SFVGTLQY+APEL Q+YT +VDYWS G L+ E +TG RPFLPN P QW +V +K++ DI V ED + + F L N+L++ LA+ E WL+ +L W P++RG + G G FK L +IL+ + V+ + G Y + E + L+ + +DTGI Q LL G ++P++ S TL+ +L ++ S +T + + P+++ L+ P++ + + ++ + Q + ++ LL L+ +A ++ +K + F+ S+ D EKY+EQ + ITS ++ AW + E+ + ++ + EV ++ + + + ++Q P R + + +++ + LR+ P + R + D+ Q MVR L Q + + K + K +L L +V + + D M V + Q KRQ +LW LL A K SG+ S+++S ++ + P + E S L AE L Q LQ+ MK Q Q Sbjct: 8 PTQTCGAWEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQE----LSPRNRERWCLEIQIMRRLNHPNVVAARDVPEGMQSLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREGAILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEQRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEMDIVVS--EDLNGAVKFSSSLPHPNNLNSVLAQRLEKWLQLMLMWHPRQRGTDPVYGPNGCFKALDDILNLKLLHVLNM-VTGTLHTYPVTEDESLQSLKARIRQDTGILEEDQELLQEAGLALIPDKPAAQCLSDGKLNEGRTLDMDLVFLFDNSRVTYESQVSPQPQ-----PESVSCILQEPKRNLPFFQLRKVWGQVWHSIQALKEDCSRLQQGQRAAMMNLLRNNSCLSKMKNSMASMSQQLKAKLDFFKTSIQIDLEKYREQT--EFGITSDKLLLAWREMEQAV-----ELCGRENEVKHLVERMMALQTDIVDLQRSPMGRKQGGTLDDLEEQARELYRRLREKPRDQRTDGDS-----QEMVRLLLQAIQGFEKKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMSEDEKM--VVRLQEKRQKELWNLLKIAC---SKVRGPVSGSPDSMNASRLSHPCQLMSQPCTAPDSLPEAAEKSEDLVAEAHTLCTQLENALQDTMKEQDQ 732
BLAST of IKKbeta vs. SwissProt
Match: gi|14285502|sp|Q60680.1|IKKA_MOUSE (RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit alpha; Short=I-kappa-B kinase alpha; Short=IKK-A; Short=IKK-alpha; Short=IkBKA; Short=IkappaB kinase; AltName: Full=Conserved helix-loop-helix ubiquitous kinase; AltName: Full=I-kappa-B kinase 1; Short=IKK1; AltName: Full=Nuclear factor NF-kappa-B inhibitor kinase alpha; Short=NFKBIKA) HSP 1 Score: 322.013 bits (824), Expect = 3.656e-97 Identity = 220/684 (32.16%), Postives = 359/684 (52.49%), Query Frame = 0 Query: 91 PGTRLGE---YVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCED-TDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRNEAGEIGI-------FKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQ----KSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGMVGEIQAIPKDRPED--MQMFVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETL----AKVFSLVRLAQVNVDALIE--NLDLFMIQVSKCQRKRQSDLWKLLAAALQQ 751 PG R G + + +LG+G FG V +++H++ +A+K CR LS K+RE+W E+ I+++L+H NVVK+ VP++L L D+PL+ ME+CSGGDLRK+LN P +CCGL + ++L++ D+ S + +LH +IIHRDLKPEN+VLQ +TI+K+IDLGYAK++ Q SL SFVGTLQY+APELF ++ YT +VDYWS G + E + G RPFL +L P W E+++KK + C+ CE+ T E+ F HL NSL + + E ESWL+ +L W+P++RG G I + F + IL+ V ++ + + ++L LQ+ +ER+TGI+ G Q LL G + P + P + +R C S + L K ++L C+ ++ L + +++ A + S Q + +L LL +L + ++ +K E F++S+ D E+Y EQ+ I+S +M +AW + E + + D + ++ + E+Q P R + M+ ++++ + L+ P + T ++ + +V ++ +DR L++ F L K+ L+ +V + + E N +FM Q KRQ ++W LL A Q Sbjct: 5 PGLRPGAGGPWEMRERLGTGGFGNVSLYQHRELDLKIAIKSCRLE----LSSKNRERWCHEIQIMKKLDHANVVKACDVPEELNFLINDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGKTIHKIIDLGYAKDVDQGSLCTSFVGTLQYLAPELFENKPYTATVDYWSFGTMVFECIAGYRPFLHHLQPFTWHEKIKKKDPK--CIFACEEMTGEVRFSSHLPQPNSLCSLIVEPMESWLQLMLNWDPQQRG----GPIDLTLKQPRCFALMDHILNLKIVHILNMT-SAKIISFLLPCDESLHSLQSRIERETGINTGSQELLSETGISLDPRK---PASQCVLDGVR--GCDSYMVYLFDKSKTVYEGPFASRSLSDCVNYIVQDSKIQLPIIQLRKVWAEAVHYVSGLKEDYSRLFQGQRAAMLSLLRYNANLTKMKNTLISASQQLKAKLEFFRKSIQLDLERYSEQMTYG--ISSEKMLKAWKEMEEKAIHYSE--VGVIGYLEDQIMSLHTEIMELQKSPYGRRQGDLMESLEQRAIDLYKQLKHRPPDHLYSDST--EMVKIIVHTVQSQDRVLKELFGHLSKLLGCKQKIIDLLPKVEVALSNIKEADNTVMFM------QGKRQKEIWHLLKIACTQ 660
BLAST of IKKbeta vs. SwissProt
Match: gi|317373368|sp|O15111.2|IKKA_HUMAN (RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit alpha; Short=I-kappa-B kinase alpha; Short=IKK-A; Short=IKK-alpha; Short=IkBKA; Short=IkappaB kinase; AltName: Full=Conserved helix-loop-helix ubiquitous kinase; AltName: Full=I-kappa-B kinase 1; Short=IKK1; AltName: Full=Nuclear factor NF-kappa-B inhibitor kinase alpha; Short=NFKBIKA; AltName: Full=Transcription factor 16; Short=TCF-16) HSP 1 Score: 317.775 bits (813), Expect = 1.140e-95 Identity = 225/735 (30.61%), Postives = 375/735 (51.02%), Query Frame = 0 Query: 91 PGTRLGE---YVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCED-TDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRNEAGEIGI-------FKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQ----KSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGMVGEIQAIPKDRPED--MQMFVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETL----AKVFSLVRLAQVNVDALIE--NLDLFMIQVSKCQRKRQSDLWKLLAAALQQKQKGDNGRSGNHQSVSSSPMASIPMPQHQGDEA-SMILYAENQALRAQLQE 801 PG R G + + +LG+G FG V +++H++ +A+K CR LS K+RE+W E+ I+++L H NVVK+ VP++L L D+PL+ ME+CSGGDLRK+LN P +CCGL + ++L++ D+ S + +LH +IIHRDLKPEN+VLQ + I+K+IDLGYAK++ Q SL SFVGTLQY+APELF ++ YT +VDYWS G + E + G RPFL +L P W E+++KK + C+ CE+ + E+ F HL NSL + + E E+WL+ +L W+P++RG G + + F + IL+ V ++ + + ++L LQ+ +ER+TGI+ G Q LL G + P + P + +R C S + L K ++L C+ ++ L + +++ A + S Q + +L LL +L + ++ +K E F +S+ D E+Y EQ+ I+S +M +AW + E + + D + ++ + E+Q P R + M+ ++++ + L+ P + T ++ + +V ++ +DR L++ F L K+ L+ +V + + E N +FM Q KRQ ++W LL A Q S +V+ A +P + D + S ++ ++ AQ+ E Sbjct: 5 PGLRPGAGGPWEMRERLGTGGFGNVCLYQHRELDLKIAIKSCRLE----LSTKNRERWCHEIQIMKKLNHANVVKACDVPEELNILIHDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGKIIHKIIDLGYAKDVDQGSLCTSFVGTLQYLAPELFENKPYTATVDYWSFGTMVFECIAGYRPFLHHLQPFTWHEKIKKKDPK--CIFACEEMSGEVRFSSHLPQPNSLCSLVVEPMENWLQLMLNWDPQQRG----GPVDLTLKQPRCFVLMDHILNLKIVHILNMT-SAKIISFLLPPDESLHSLQSRIERETGINTGSQELLSETGISLDPRK---PASQCVLDGVR--GCDSYMVYLFDKSKTVYEGPFASRSLSDCVNYIVQDSKIQLPIIQLRKVWAEAVHYVSGLKEDYSRLFQGQRAAMLSLLRYNANLTKMKNTLISASQQLKAKLEFFHKSIQLDLERYSEQMTYG--ISSEKMLKAWKEMEEKAIHYAE--VGVIGYLEDQIMSLHAEIMELQKSPYGRRQGDLMESLEQRAIDLYKQLKHRPSDHSYSDST--EMVKIIVHTVQSQDRVLKELFGHLSKLLGCKQKIIDLLPKVEVALSNIKEADNTVMFM------QGKRQKEIWHLLKIACTQSSARSLVGSSLEGAVTPQTSAWLPPTSAEHDHSLSCVVTPQDGETSAQMIE 711
BLAST of IKKbeta vs. SwissProt
Match: gi|75073791|sp|Q95KV1.1|IKKA_BOVIN (RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit alpha; Short=I-kappa-B kinase alpha; Short=IKK-A; Short=IKK-alpha; Short=IkBKA; AltName: Full=I-kappa-B kinase 1; Short=IKK1; AltName: Full=Nuclear factor NF-kappa-B inhibitor kinase alpha; Short=NFKBIKA) HSP 1 Score: 312.768 bits (800), Expect = 8.203e-94 Identity = 214/685 (31.24%), Postives = 356/685 (51.97%), Query Frame = 0 Query: 91 PGTRLGE---YVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCED-TDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRNEAGEIGI-------FKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQ----KSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGMVGEIQAIPKDRPED--MQMFVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNK-------KETLAKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQQ 751 PG R G + + +LG+G FG V +++H++ +A+K CR LS K+RE+W E+ I+++L H NVVK+ VP++L L D+PL+ ME+CSGGDLRK+LN P +CCGL + ++L++ D+ S + +LH +IIHRDLKPEN+VLQ + ++K+IDLGYAK++ Q SL SFVGTLQY+APELF ++ YT +VDYWS G + E + G RPFL +L P W E+++KK + C+ CE+ T E+ F HL NSL + + E E+WL+ +L W+P++RG G + + F + IL+ V ++ + + ++L LQ+ +ER+TGI+ G Q LL G + P + P + +R C S + L K ++L C+ ++ L + +++ A + S Q + +L LL +L + ++ +K E F +S+ D E+Y EQ+ I+S +M +AW + E + + D + ++ + E+Q P R + M+ ++++ + L+ P + T ++ + +V ++ +DR L++ F K+ + + V +A N+ ++ +FM Q KRQ ++W LL A Q Sbjct: 5 PGLRPGAGGPWEMRERLGTGGFGNVCLYQHRELDLKIAIKSCRLE----LSTKNRERWCHEIQIMKKLNHANVVKACDVPEELNFLINDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGKIMHKIIDLGYAKDVDQGSLCTSFVGTLQYLAPELFENKPYTATVDYWSFGTMVFECIAGYRPFLHHLQPFTWHEKIKKKDPK--CIFACEEMTGEVRFSSHLPQPNSLCSLIVEPMENWLQLMLNWDPQQRG----GPVDLTLKQPRCFVLMDHILNLKIVHILNMT-SAKIISFLLPPDESLHSLQSRIERETGINTGSQELLSEMGISLDPRK---PASQCVLDGVR--GCDSYMVYLFDKSKTVYEGPFASRSLSDCVNYIVQDSKIQLPIIQLRKVWAEAVHYVSGLKEDYSRLFQGQRAAMLSLLRYNTNLTKMKNTLISASQQLKAKLEFFHKSIQLDLERYSEQMTYG--ISSEKMLKAWKEMEEKAIHYAE--VGVIGYLEDQIMSLHTEIMELQKSPYGRRQGDLMESLEQRAIDLYKQLKHRPSDHSYSDST--EMVKIIVHTVQSQDRVLKELFGHLSKLLGCKQKIIDLLPKVEMALSNIKE-ADSTVMFM------QGKRQKEIWHLLKIACTQ 660
BLAST of IKKbeta vs. SwissProt
Match: gi|82233772|sp|Q5ZJB4.1|IKKA_CHICK (RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit alpha; Short=I kappa-B kinase alpha; Short=IKK-A; Short=IKK-alpha; Short=IkBKA; Short=IkappaB kinase; AltName: Full=Conserved helix-loop-helix ubiquitous kinase; AltName: Full=Nuclear factor NF-kappa-B inhibitor kinase alpha; Short=NFKBIKA) HSP 1 Score: 312.768 bits (800), Expect = 1.335e-93 Identity = 217/680 (31.91%), Postives = 360/680 (52.94%), Query Frame = 0 Query: 91 PGTRLGEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRN---EAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRV------KLTMPKTLESCLKNPRKEVNRSLQKSIYSHA--YFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFN--DIRSKRQEVNDILGEVNGMVGEIQAIPKDR--PEDMQMFVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETL----AKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQQ 751 P G + + +LG+G FG V +++HQ +G +A+K CR LS K++++W E+DI+++L HPNVV++ VP+++ L D+PL+ ME+CSGGDLRK+LN P +CCGL + ++L++ D+ S + +LH RIIHRDLKPEN+VLQ + I+K+IDLGYAK+L Q SL SFVGTLQY+APELF ++ Y+ +VDYWS G + E + G RPFL NL P W E+++KK + I + E E+ F HL +S+ + + E ESWL+ +L W+P++RG E F + IL+ V ++ + + ++L LQ +E +TGI G+Q LL+ G + P + P + +R Y + + DK K V ++ + + +++ + ++ + +++ A Y +E+ L Q +L L NN A Q+ +A K E F +S+ D E+Y +Q+ I+S +M +AW + E + DI +++ + E+ E+Q P R E M+ ++++ + L+ P + T D+ + +V+ ++ +DR L++ F L K+ L+ +V ++ + E + M + Q KRQ ++W LL A Q Sbjct: 22 PAGGCGPWEMRDRLGTGGFGNVCLYQHQDTGARVAIKSCRLE----LSVKNKDRWCHEIDIMKKLNHPNVVRACEVPEEMNFLVNDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIQYLHENRIIHRDLKPENIVLQDEGGKIIHKIIDLGYAKDLDQGSLCTSFVGTLQYLAPELFENKSYSVTVDYWSFGTMVFECIAGFRPFLHNLQPFTWHEKIKKKDPKHIFASE-EMNGEVRFSTHLPQPHSICSLIVEPMESWLQLMLNWDPEQRGGGLDPETNSPKCFLLMDHILNLKIVHILNM-TSAKIVSFLLHPEESLHFLQNRIESETGISTGNQELLLETGICLDPRK---PASQCVIDGVRGWDSYM----VYLFDKSKTVYDGPFASRSLSECVNYIVQDSKIQLPIPQLRKVWAEAVHYVIGLKEDYSRLFQGQRAAMLSLLRYNANLIKMKNNMVSASQQLKA--KLEFFHQSIRLDLERYSDQMA--YGISSEKMLKAWKEMEEKASHCAQAEDIGYLDEQIMALHTEIV----ELQKSPYARRQGEVMESLEQRAIDLYKQLKTRPPDHAYSDST--DMVKIIVQTVQSQDRVLKELFGHLSKLLGCKQKIIDLLPKIEVALNNIKEADNSEM----QMQGKRQREIWHLLKIACTQ 674
BLAST of IKKbeta vs. SwissProt
Match: gi|82183996|sp|Q6GM53.1|IKKA_XENLA (RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit alpha; Short=I kappa-B kinase alpha; Short=IKK-A; Short=IKK-alpha; Short=IkBKA; AltName: Full=Conserved helix-loop-helix ubiquitous kinase; AltName: Full=Nuclear factor NF-kappa-B inhibitor kinase alpha; Short=NFKBIKA) HSP 1 Score: 301.597 bits (771), Expect = 1.559e-89 Identity = 211/677 (31.17%), Postives = 361/677 (53.32%), Query Frame = 0 Query: 89 ISPGTRLGEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRN-EAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRV------KLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGMVGEIQAIPKDRPEDMQMFVKKSLQ--GLEDLRQI-PLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETL----AKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQQ 751 + G G + + +LG+G FG V +++++++G++ A+K CR LS K++E+W QE+ I++RL HPNVVK+ VP ++ L D+P + ME+C+GGDLRK+LN P +CCGL + +VL + D+ S + +LH RIIHRDLKPEN+VLQ + +T++K+IDLGYAK+L Q SL SFVGTLQY+APELF ++ Y+ +VDYWS G ++ E + G RPFL N+ P W E+++KK + I ++ E + EI F L N+L + + + E+WL+ LL W+P +RG + G F + +I S V ++ + + L+ LQ+ +ER+TGI +Q LL+ G + P + P + ++ Y + + DK K V ++ + L +++ + ++ + +++ A + S Q + +L LL +L + ++ +K + F+ S+ D E+Y +Q+ I+S +M AW + E F K E++ + + G+ EI + + Q V + L+ +E +Q+ P K ++ + +V+ ++ +DR L++ F L K+ L+ ++ V+ I+ D ++Q+ Q KRQ ++W LL A Q Sbjct: 6 VQHGAVCGPWDMKDRLGTGGFGNVCLYQNRETGELKAIKSCRLE----LSVKNKERWCQEIQIMKRLNHPNVVKACDVPPEMDFLVNDVPHLAMEYCAGGDLRKLLNKPENCCGLKESQVLNLISDIGSGIQYLHENRIIHRDLKPENIVLQECNGKTVHKIIDLGYAKDLDQGSLCTSFVGTLQYLAPELFENKPYSVTVDYWSFGTMAFECIAGFRPFLHNMQPFTWHEKIKKKDHKHIYAYE-EMSGEIRFSTSLPEPNNLCSIIVDKIETWLQLLLNWDPVQRGGGIDCGRPRCFMLMDQIFSLKIVHILNMT-SAKIHSFHLQPEESLHTLQSRIERETGISTCNQELLLEMGVSLDPRK---PASQCVIDGVKGWDSYM----VYLFDKSKTVYEGPFQSRSLSECLNYIVQDSKVQLPIPQLRKVWAEAVHYVSGLKEDYSRLFQGQRAAMLSLLRFNTNLTKMKNTMVSASQQLDAKLQFFKRSIEIDLERYSDQMA--YGISSEKMLRAWKEMEDKAVCF-----GKAGEIHFLDETIMGLHTEIVELQRSPCARRQGDVMEHLEQRAMELYKQLKPRSPDKAYSDSTEMVKILVQTVQGQDRVLKELFGHLSKLLGCKQKIIDLLPQIEMTVNN-IKEADSSLMQM---QAKRQREIWHLLKIACTQ 658
BLAST of IKKbeta vs. SwissProt
Match: gi|119371145|sp|Q4G3H4.1|IKKA_DANRE (RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit alpha; Short=I kappa-B kinase alpha; Short=IKK-A; Short=IKK-alpha; Short=IkBKA; Short=IkappaB kinase; AltName: Full=Conserved helix-loop-helix ubiquitous kinase; AltName: Full=I-kappa-B kinase 1; Short=IKK1; AltName: Full=Nuclear factor NF-kappa-B inhibitor kinase alpha; Short=NFKBIKA) HSP 1 Score: 300.442 bits (768), Expect = 5.336e-89 Identity = 227/739 (30.72%), Postives = 382/739 (51.69%), Query Frame = 0 Query: 96 GEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLE-EDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTD-EIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRG---RNEAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKG-KDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLR-----IIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGMVGEIQAIPKDRPEDMQMFVKKSLQ--GLEDLRQI--------PLEGRKEKDTVLDVAQNMVRCLKQRDRNLQD-YFNKKETLAKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLA-AALQQKQKGDNGRSGNHQSVSSS------------PMASIPMPQHQGDEASMILYAENQALRAQL 799 G +V + +LG+G FG V+++++Q++ + +A+K CR L+ K++++W + + I+++L+H NVV + VP++++ + DLPL+ ME+CS GDLRK+L+ P +CCGL + EVL++ D+ S + +LH +IIHRDLKPEN+VLQ + + ++K+IDLGYAK+L Q SL SFVGTLQY+APELF + YT +VD+WS G + E G RPFL NL P QW +V K +DI ED + E+ F HL N+LS TL E E L+ +L+W+P +RG ++ + F L +ILS V + ++ ++ L +G LQ +E +T I + +Q LL G P + P + +R I+Y + M R T+P+++ ++ + ++ S K ++ A + Q + +L LL +L + ++ +K + F+ S+ +D EKY +Q++ I+S +M +AW+++E F ++ E+ + E+ + EI + + Q V + LQ +E +Q+ P G + ++ V +V+ ++ +DR L+D Y + + L ++ L ++ +E + V + Q KRQ + W LL A Q + +SG S S+ PM S+ +P H+GD + +L ENQ QL Sbjct: 13 GSWVMKERLGTGGFGHVYLYQNQETSEKIAVKLCRLE----LNSKNKDRWSRGIQIMKKLKHLNVVTAKDVPEEMMHIALNDLPLLAMEYCSKGDLRKLLSKPENCCGLKESEVLSLLNDVGSGIQYLHENKIIHRDLKPENIVLQEINGKLVHKIIDLGYAKDLDQGSLCTSFVGTLQYLAPELFEGKSYTVTVDFWSFGTMIFECCCGFRPFLHNLQPVQWTSKVRNKGPKDIMA--VEDMNGEVRFSTHLPYPNNLSRTLLEPLEGLLQLMLKWDPVQRGLGLNTDSKQPQCFVLLDQILSMKVVHI--LNMTTTQVHSFLLSPDEGLHSLQQRIENETKIELLNQDLLQETGVMSDPRK---PAAQCVLDGVRGWDSYIVYLFDKSLTKYMGPLTAR---TLPESVNFIVRETKTQLPLSTLKKVWGEAVSYICGLREDYSRLFQGQRAAMLSLLRFNTNLTRYKNMMFSFSQQLKAKLDFFKTSIQYDLEKYSDQMQ--YGISSEKMLKAWHENEERAAAF-----AQVAEIGHLDEEIMALHSEIVELQRSPYARRQGDVMEQLQEKAIELYKQLKAKCKMPDPQHGYSDSSEMVKV---IVQTVQNQDRVLRDLYAHLSKILLSKQKIIDLFP-KIERTLECIKEADTTVMQMQIKRQREFWHLLKIACAQNTTRSSVSQSGEMPSSLSTWNQTQAQCSSRLPM-SLQVP-HEGDSVNHLL-EENQRYLTQL 723
BLAST of IKKbeta vs. nr
Match: gi|1325307975|ref|XP_023335608.1| (inhibitor of nuclear factor kappa-B kinase subunit beta-like isoform X1 [Eurytemora affinis] >gi|1325307977|ref|XP_023335609.1| inhibitor of nuclear factor kappa-B kinase subunit beta-like isoform X1 [Eurytemora affinis]) HSP 1 Score: 459.914 bits (1182), Expect = 3.186e-147 Identity = 273/667 (40.93%), Postives = 391/667 (58.62%), Query Frame = 0 Query: 97 EYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRNEAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGMVGEI--QAIPKDRPED--MQMFVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETLAKVFSLVRLAQVNVDALIENLDLFMIQVS---------KCQRKRQSDLWKLLAAALQ 750 E+VC+ QLGSG FG+VHVWR+ + Q ALKK +FG++ L+ +H+ QW QEVDI+ RL+H NVV+ S+P L DLP +CME+C GDLR++LN +C GL + ++L + D+ SALG+LHNRRIIHRDLKPENVVL+ T R +YKLIDLGYAKELG SSLA SFVGTLQY+APELFL Q+YTKSVDYWSLG L HEI+TG+RPFLP+LSPGQW++ VE+K + I V + D +I ++E+L PE +S LA E WLRSLL+W +RRGR+ G + +F L +IL R+ V + R Y LQ + DT I +QLLL +G +I E+ L F+ E L I S L +++++K V+ +P ++ L++ ++ V K + H Y F +QE R LK L ++ T I+D + +Q +R + E F SL HD +Y EQ +K ITS +M E+WN S D+ + +R++ + + + + E+ + D P D ++ +SL+ + LR+ R + T ++AQ +VR L++RD+ L + L +L ++ VD+L N ++ S K Q +RQSD+W LLAAA++ Sbjct: 4 EWVCENQLGSGGFGIVHVWRNILTNQKYALKKFKFGSETLLTARHKTQWCQEVDIMLRLDHMNVVRCYSIPPGLDPGSTDLPSLCMEYCESGDLRRLLNKIENCRGLLESQILPVLNDVTSALGYLHNRRIIHRDLKPENVVLKSTQTRMVYKLIDLGYAKELGVSSLAKSFVGTLQYVAPELFLEQDYTKSVDYWSLGLLCHEIVTGQRPFLPHLSPGQWVDHVEQKLQNHIAVLETVD-GKIVYQENLVPETRISRKLALRLEDWLRSLLDWSAERRGRDTHGNVVVFTQLNKILREKRLDVFNL-RNKTVHCYAAETSFSFNHLQAQILADTNISAENQLLLTDHGYKITREDD-LDQFT--EAELPIFLVDMSSMSLKLSEQLKCVQFQIPVLVQQFLRDTKRSVQDYHLKLMNVHGYHFIAQECRTHELMAIGLKTLFSYIKTEIQDF--STLTFSQDLQRLEANMEFFTSSLNHDLSRYDEQAQKKDRITSVKMIESWNSSRTDILSSLDTLRTRTCILEESIKTAETGIREVERETTILDPPSDPALKELEGRSLRLYDGLRRERASNRVDT-TPREIAQIVVRMLRRRDQLLN---------STCSLLCKLRRLVVDSLDINQAAGVVSTSFQTLGESLIKAQTRRQSDIWTLLAAAIK 653
BLAST of IKKbeta vs. nr
Match: gi|341650458|gb|AEK86518.1| (IKKbeta [Litopenaeus vannamei]) HSP 1 Score: 434.491 bits (1116), Expect = 5.461e-137 Identity = 255/726 (35.12%), Postives = 400/726 (55.10%), Query Frame = 0 Query: 104 LGSGSFGVVHVWRHQKSGQILALKKCRFGT-----DVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGR----NEAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGMVGEIQAIPKDRPEDMQMFVKKSLQGLED----LRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETLAKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLL-------------AAALQQKQKGDNGRSGNHQSVSSSPMASIPMPQHQGDEASMILYAENQALRAQLQEYM 803 LG+G FG V +WRH +G+ +ALKKCR+GT + L+ KH E+W +EV+I+ RL H VV+ VP +L + DLP++CME+CSGGDLRK+LN P +CCGL + V + D+ A+ +LH+ RIIHRDLKPEN+VLQ +T+YKLIDLGYAKEL QSS+ SFVGTLQY+APELFLS+ YT +VDYWSLG ++HEI+TG RPFLPN++P +WM++V K +CV++ + EI F H+FPE +S L E WLR +LEW+P RG+ + A + F + +IL++ ++V VD L+Y + E T ++Q W+ RD+G+ V Q L+P GQ P + ++ + + ++Y ++ G+T +V P +E+ L+ PR V Q+ +++HA FF +E R Q+ KV +L L++ L Q++ + ++ LF E+L D + Y EQ +TS +++ W + + + + Q++ L +N + E+Q P R + L ED LR+ E R D+ + +++ L++RDR QD + E ++ S V ++A++++ +S Q++RQ D+WK++ A +Q Q N + S + ++S+ + + S + AEN+A R Q+ E + Sbjct: 19 LGTGGFGTVTLWRHNDTGETIALKKCRWGTPGTGTENILTPKHVERWEKEVEIMNRLNHQAVVRCFPVPDELTGPQGDLPMLCMEYCSGGDLRKVLNKPENCCGLREAAVRSCIRDMTEAVAYLHSMRIIHRDLKPENIVLQDVDGKTVYKLIDLGYAKELEQSSVCTSFVGTLQYLAPELFLSKRYTCTVDYWSLGLVTHEIITGIRPFLPNMTPVEWMKRVRTKQSHHVCVYEGRN-GEIQFSSHMFPECHISQPLRTRIEEWLRIMLEWDPVLRGQVLDEDSAKQFVAFNMINDILNKKMIKVFVVDL-CRLLEYEVTESTSLSEVQQWVARDSGVLVDDQRPLLPRGQPPDPTRPAIQCWAPPDEDEWLLYIFAE--GMTRP----QVPPHFPPLVEAMLREPRTAVEYQTQRRMWAHAVFFLHREARLLTLLTQAQKVSMLHLMSGHAQLTKTGQRMLSDIAKLQARHHLFMEALNTDLDYYDEQASSG-RLTSEKLYSGWREMGEVTLRQVHAVVERVQQLEGSLTALNTRILELQCSPFARARAIDSL-DSVLTAGEDHYCNLRRRNKEQRATPHDNTDMCKLLLQALRKRDRLQQDLYKHVEKQSECCSEVAALSSPLEAVLQDAARTAQHISSLQKQRQKDIWKIMEIAINHSRTVGTAAGMVQAPQPVPNASQLPKKPPSPAVLSSLNNLLEKSKKESDAIIAENRAXRCQMVEML 734
BLAST of IKKbeta vs. nr
Match: gi|1228009951|ref|XP_021936901.1| (inhibitor of nuclear factor kappa-B kinase subunit alpha-like isoform X1 [Zootermopsis nevadensis] >gi|646699581|gb|KDR10135.1| Inhibitor of nuclear factor kappa-B kinase subunit alpha [Zootermopsis nevadensis]) HSP 1 Score: 432.565 bits (1111), Expect = 4.075e-136 Identity = 257/681 (37.74%), Postives = 395/681 (58.00%), Query Frame = 0 Query: 95 LGEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRG----RNEAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEI-LPEESL---LPMFSTLEPNLRIIYCY--SSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGMVGEIQAIPKDRPEDMQMFVKKSLQG---LEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQD-YFNKKETLAKVFSL-VRLAQV--NVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQQKQKGDNG 758 + +V + LGSG FG V +WRH+ +++ALKKCR GTD L+EKH+E+W +EV+I+QRL HPNVVK+++VP DL L LPLMCMEFCS GDLR++LN +CCGL + EV ++ D+ SA+ +LH+ +I HRDLKPEN+VLQ R +YKLIDLGYAKEL QSS+ SFVGTLQY+APELF+S+ Y SVDYWSLG +SHE++TG RPFLPN++P WM V +K+ DIC ++ ED I F + LF +N +S+ L E WL+ LLEW+ +RG RN+ +I +F + +ILS+ + V V N L Y + + T LQTW+ERDT I V Q LL+ +GQ + +E+ +P + ++Y Y SL I+ ++P+T+ ++ PR +V QK ++HA FF QE F Q+ +V +L +++ LN Q + ++ ++ +L ESL D ++Q KK + S ++ +W++ + ++ ++ NG ++Q P + D ++ + +G + LR+ P E R E+ +++ + + CLK RD+ L+D FN L +V + + + Q+ +++ ++ ++ +++ + Q RQ D+W LQ Q NG Sbjct: 12 VANWVRERVLGSGGFGQVTLWRHKTKDEMIALKKCRTGTDAILTEKHKERWSKEVEIMQRLNHPNVVKAIAVPPDLAVLRSKLPLMCMEFCSKGDLRQVLNRSENCCGLCEAEVRSLISDVKSAVQYLHSMKITHRDLKPENIVLQQEEDRIVYKLIDLGYAKELDQSSICTSFVGTLQYLAPELFMSKTYNYSVDYWSLGLVSHEVITGVRPFLPNMAPVSWMTHVREKSSDDICAYKAED-GTIVFSKELFLQNHISSCLKCYVEKWLKLLLEWDAAKRGRILNRNKELQIVVFDLIEDILSKKIINVFSVPSYQN-LSYEIDDSTAVSTLQTWIERDTRIPVQEQELLLSSGQPFDISKEACQCWVPQTLNNQNVNTMVYVYHRGSLA-------IQNFAPSVPQTVSKMMEEPRNKVEFVHQKRAWAHAVFFLQQEMELYHAFLQAYRVKMLHVISSNAKLNEQTQAVVSHLQQVEAQLQLILESLHFD----EDQAKK-IGFFSEEVMHSWSKMNASVGRRIAKLKEIVSQLESKCDVANGKTMDLQRNPYTKMADHEVLMSLLEEGQKRYDSLRRRPKENRYEQTDNVEMVKIVYNCLKHRDKLLRDKTFNAH--LQQVIDVQMEIEQLWNPLNSSVQVINKVQMELKQTQLDRQHDIW------LQMTQDSCNG 670
BLAST of IKKbeta vs. nr
Match: gi|1350353424|gb|AVI10168.1| (inhibitor of nuclear factor kappa-B kinase beta [Scylla paramamosain]) HSP 1 Score: 431.024 bits (1107), Expect = 1.361e-135 Identity = 258/737 (35.01%), Postives = 406/737 (55.09%), Query Frame = 0 Query: 104 LGSGSFGVVHVWRHQKSGQILALKKCRFGT-----DVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRNEAGEIG-----IFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDF----FNDIRSKRQEVNDILGEVNGMVGEIQAIPKDRP---EDMQMFVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETLAKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQQKQKGDNGRSGNHQSVSSSPMASIPMPQH--------------------QGDEASMILYAENQALRAQLQEYM 803 LG+G FG V +WRH +G+ +ALKKCR+GT + L+ KH E+W +EV+I+ RL H VV+ VP +L DLP++CME+CS GDLRK+LN P +CCGL + V A D+ A+ +LH+ RIIHRDLKPEN+VLQ + +YKLIDLGYAKEL SS+ SFVGTLQY+APELFLS+ YT +VDYWSLG ++HEI+TG RPFLPN++P +WM++V K ICV++ + D + F H+FPE+ +S+ E WLR +LEWEP RG+ + GE G F + +IL++ ++V VD L+Y + E + ++Q W+ +D+G+ + Q L+P GQ P + ++ + + ++Y ++ G+T +V P +E+ L+ PR V+ Q+ ++SHA FF +E R Q+ KV +L L++ L Q++ + ++ LF E+L D + Y EQ +TS +++ W RD+ + + + + Q++ L +N + E+Q P R + ++ + + +R+ E R D+ + +++ L++RDR QD F E ++ S V ++ ++E+ +S Q++RQ D+WK++ A+ ++ RS + S + M IP +H G EA I+ AEN+ALR Q+ E + Sbjct: 21 LGTGGFGTVTLWRHTDTGETIALKKCRWGTPGTGTENILTPKHVERWEKEVEIMNRLSHSAVVRCFQVPAELTGPPGDLPMLCMEYCSLGDLRKVLNKPENCCGLREASVRACIRDITEAVAYLHSMRIIHRDLKPENIVLQDVDGKIVYKLIDLGYAKELDHSSVCTSFVGTLQYLAPELFLSKRYTCTVDYWSLGLVTHEIITGVRPFLPNMTPVEWMKRVRTKQSNHICVYEGRNGD-VQFSAHMFPESHISSPFRLRLEEWLRVMLEWEPGVRGQVQ-GEDGSKKVLAFTMINDILNKKMIKVFVVDLCC-LLEYEVTESSSLSEVQKWVAQDSGVAIEDQRPLLPRGQPPDPTRPAIQCWAPPDEDEWLLYIFAE--GMTRP----QVPPHFPPLVEAMLREPRTTVDYQTQRRMWSHAMFFLQREARLLALLMQAQKVSMLHLMSGHAQLTKTGQRMLSDIAKLQARHHLFMEALNTDLDYYDEQASSG-RLTSEKLYSGW----RDMGEITLRQVHVVVERVQQLEGSLTALNTRILELQCSPFARARSNDTLENIISAGEELYCTMRRRNKEQRATAHDNTDMCKLLLQALRKRDRLQQDLFKHIEKQSECCSEVAELSSPLETVLEDAARTAQHISSLQKQRQKDIWKIMEIAI------NHSRSVGNPSSLPANMQPIPNAKHLAKKPPSPAALSSLSALLEKSGKEADAII-AENRALRCQMVEML 736
BLAST of IKKbeta vs. nr
Match: gi|1339046424|ref|XP_023711368.1| (inhibitor of nuclear factor kappa-B kinase subunit alpha [Cryptotermes secundus] >gi|1339046426|ref|XP_023711369.1| inhibitor of nuclear factor kappa-B kinase subunit alpha [Cryptotermes secundus] >gi|1330905953|gb|PNF29865.1| hypothetical protein B7P43_G09538 [Cryptotermes secundus]) HSP 1 Score: 426.402 bits (1095), Expect = 1.058e-133 Identity = 247/663 (37.25%), Postives = 373/663 (56.26%), Query Frame = 0 Query: 104 LGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGR----NEAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPN------LRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGMVGEIQ---AIPKDRPEDMQMFVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETLAKVFSLVRLAQVNVDALIENL-----------DLFMIQVSKCQRKRQSDLW 742 LGSG FG V +WRH+ +++ALKKCR GTD L+EKH+E+W +EV+I+QRL+HPNVVK+++VP DL L LPLMCMEFCS GDLR++LN +CCGL + EV + D+ SA+ +LH+ +I HRDLKPEN+VLQ + +YKLIDLGYAKEL QSS+ SFVGTLQY+APELF+S+ Y SVDYWSLG +SHE++TG RPFLPN++P WM V +K+ DIC +Q +D I F + LF +N +S++L E WL SLLEW+ +RGR N+ EI +F + +ILS+ V + V L Y + + T LQ W++RDTG+ V Q LL+P+GQ + + +P+ + ++ + SL I +V ++P T+ +++PR V QK ++HA FF QE F ++ +V +L ++ LN Q + + ++ +++ LF +SL + E K + + +W L+ ++ ++ VN ++Q I +D E + ++ + ++LR+ P E R+E+ +++ + + CLK RD+ L D F V+V A IE L + +++ + Q RQ D+W Sbjct: 18 LGSGGFGQVTLWRHKTKDEMIALKKCRTGTDALLTEKHKERWSKEVEIMQRLDHPNVVKAIAVPPDLAVLRSKLPLMCMEFCSKGDLRQVLNRSENCCGLCEAEVRLLISDVKSAVQYLHSMKITHRDLKPENIVLQQVKDKIVYKLIDLGYAKELDQSSICTSFVGTLQYLAPELFMSKTYNYSVDYWSLGLVSHEVITGVRPFLPNMAPVSWMTHVREKSSDDICAYQAQD-GSIVFSKELFHQNHISSSLKYHMEKWLTSLLEWDAAKRGRAINKNKELEIVVFDMIEDILSKKIVNIFSVP-TYQHLSYEVDDSTAISTLQLWMKRDTGVPVEQQELLLPSGQPFDMTKEACQCWVPPDPHNQSSKPMVYLFLHGSLA-------IGKVTPSIPVTVGKMMEDPRHRVEYIHQKRAWAHAVFFLRQEMELYQTFMEAYRVKMLHIILNNARLNEQAQAVVSRLQQVEAQFHLFIDSL-----HFDEDEAKRIDFFPEHIVHSWTTVSSALSVRMAKLKEVVSQLQSKCDVVNSRTIDLQRNTCIKRDH-EVLVSLLETGQKRYDNLRRRPKESRQERTDNVEMVKVVYNCLKHRDKLLND---------NAFDTHLQQVVDVQAEIEQLWNPLRSSLQVMNKVQMELRQMQLDRQRDIW 656
BLAST of IKKbeta vs. nr
Match: gi|1355995747|gb|PRD35841.1| (chuk [Nephila clavipes]) HSP 1 Score: 395.586 bits (1015), Expect = 7.049e-122 Identity = 231/694 (33.29%), Postives = 384/694 (55.33%), Query Frame = 0 Query: 91 PGTRLGEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDE-IHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRNEAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGMVGEIQAIPKDRPEDMQMFV---KKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETLAKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQQKQKGDNGRSGNHQSVSSSPMASIPMPQHQ 780 P +G++ + LG+G FG V +WR++ S + +ALK+CR+G D ++ KHR +W+ EVD++ RL HPNVV +++VP +L ++PL+ ME+CS GDLRK+LN P +CCGL + V I ++SA+ +LH+ RIIHRDLKPEN+V+Q + TIYKLIDLGYAKEL Q S SFVGTLQY+APELF+SQ+YT +VDYWSLG L+HEI+TG+RPFLP+ SP +W+ + K K + D D+ I F + + P + + + D E WL+++LEW+PK+RG+ E+G F L + + V CVD +I+ E +D LE++T I V Q + P+G +E + S +E I++ ++ + + I +P +E+ ++NP +VN Q++I+S A + S QE+ Q+ K ++ LLT+ + + ++ + + ++K LF+ SL D + Y++Q ++ ++ + E W + +L + +R K + + E+Q P R + F +K L +LR+ + R+ +++ + + CL+ +D + + ++ + + L++ + + Q+ Q KRQ LWK++ A +++ Q + RS + +SSSP +P+ Q Sbjct: 6 PVEEIGQWKKEKVLGAGGFGYVVLWRNKISNETIALKECRWGHDPMMTPKHRSRWKLEVDMMSRLNHPNVVTAIAVPPELDVPATEMPLLAMEYCSNGDLRKLLNKPENCCGLKEMHVRLIMKHISSAVNYLHSLRIIHRDLKPENIVIQDQNGNTIYKLIDLGYAKELDQGSFCTSFVGTLQYLAPELFMSQKYTCTVDYWSLGLLTHEIITGQRPFLPDKSPAEWIPII--KGKNSTVIRAYLDADKNIIFSDEIAPFHHICSIFKTDVERWLQTMLEWDPKKRGKYESG--SAFNLLETMFQKKISHVFCVDTLTLH-SFIINETMSLEDFYKELEKETKIPVSQQEIFSPDGHSSELKEGVSQFVSDMEEEETIVFLFNK--NESQSSMITSSSTVIPSDVENMMRNPHDKVNYQQQRNIWSQAVYLSQQESSLINKLIQAFKANLMSLLTKASYVRKSISRMTAEMNKLLAKCSLFKSSLEQDIKSYEKQ-SQNGGFSAETLLEDWKSNFENLKK-VDILRQKIVNLEACTSNIATRTAELQKSPYVRSKQSTSFEDVHQKILNSFAELRKRSSDERRIPHDNVEIVRLLCLCLQHSHTLTEDVIIHIKIVKQIKRDIDDCLPQIGNLLKEISDWEFQIDSWQSKRQQALWKVINALIEKAQHAE--RSISPLVLSSSPQT---LPKRQ 685
BLAST of IKKbeta vs. nr
Match: gi|1325307979|ref|XP_023335610.1| (inhibitor of nuclear factor kappa-B kinase subunit beta-like isoform X2 [Eurytemora affinis]) HSP 1 Score: 390.193 bits (1001), Expect = 4.032e-121 Identity = 242/610 (39.67%), Postives = 348/610 (57.05%), Query Frame = 0 Query: 154 RLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRNEAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGMVGEI--QAIPKDRPED--MQMFVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETLAKVFSLVRLAQVNVDALIENLDLFMIQVS---------KCQRKRQSDLWKLLAAALQ 750 RL+H NVV+ S+P L DLP +CME+C GDLR++LN +C GL + ++L + D+ SALG+LHNRRIIHRDLKPENVVL+ T R +YKLIDLGYAKELG SSLA SFVGTLQY+APELFL Q+YTKSVDYWSLG L HEI+TG+RPFLP+LSPGQW++ VE+K + I V + D +I ++E+L PE +S LA E WLRSLL+W +RRGR+ G + +F L +IL R+ V + R Y LQ + DT I +QLLL +G +I E+ L F+ E L I S L +++++K V+ +P ++ L++ ++ V K + H Y F +QE R LK L ++ T I+D + +Q +R + E F SL HD +Y EQ +K ITS +M E+WN S D+ + +R++ + + + + E+ + D P D ++ +SL+ + LR+ R + T ++AQ +VR L++RD+ L + L +L ++ VD+L N ++ S K Q +RQSD+W LLAAA++ Sbjct: 3 RLDHMNVVRCYSIPPGLDPGSTDLPSLCMEYCESGDLRRLLNKIENCRGLLESQILPVLNDVTSALGYLHNRRIIHRDLKPENVVLKSTQTRMVYKLIDLGYAKELGVSSLAKSFVGTLQYVAPELFLEQDYTKSVDYWSLGLLCHEIVTGQRPFLPHLSPGQWVDHVEQKLQNHIAVLETVD-GKIVYQENLVPETRISRKLALRLEDWLRSLLDWSAERRGRDTHGNVVVFTQLNKILREKRLDVFNL-RNKTVHCYAAETSFSFNHLQAQILADTNISAENQLLLTDHGYKITREDD-LDQFT--EAELPIFLVDMSSMSLKLSEQLKCVQFQIPVLVQQFLRDTKRSVQDYHLKLMNVHGYHFIAQECRTHELMAIGLKTLFSYIKTEIQDF--STLTFSQDLQRLEANMEFFTSSLNHDLSRYDEQAQKKDRITSVKMIESWNSSRTDILSSLDTLRTRTCILEESIKTAETGIREVERETTILDPPSDPALKELEGRSLRLYDGLRRERASNRVDT-TPREIAQIVVRMLRRRDQLLN---------STCSLLCKLRRLVVDSLDINQAAGVVSTSFQTLGESLIKAQTRRQSDIWTLLAAAIK 595
BLAST of IKKbeta vs. nr
Match: gi|1316175393|ref|XP_023233196.1| (inhibitor of nuclear factor kappa-B kinase subunit alpha-like [Centruroides sculpturatus] >gi|1316175395|ref|XP_023233197.1| inhibitor of nuclear factor kappa-B kinase subunit alpha-like [Centruroides sculpturatus] >gi|1316175397|ref|XP_023233198.1| inhibitor of nuclear factor kappa-B kinase subunit alpha-like [Centruroides sculpturatus]) HSP 1 Score: 390.963 bits (1003), Expect = 5.305e-120 Identity = 239/723 (33.06%), Postives = 396/723 (54.77%), Query Frame = 0 Query: 89 ISPGTRLGEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRNEAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRS-KRQEVNDILGEVNGMVGEIQAIPKDR---PEDMQMFVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETLAKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQQKQKGDNGRSGNHQSV----SSSPMASIPMPQHQGDEASMILYAENQALRAQLQEYM 803 + GT + ++ LG G FG+V +W+ + S + +ALK+CR+G D ++ KH+ +W+ EVDI++RL HPNVVK++ VP L E +LPL+ ME+CSGGDLRK+L+ +CCGL + EV + +A+A+ +LH++RIIHRDLKPEN+VLQ + IYKLIDLGYAKEL Q SL SFVGTLQY+APELF+ +Y+ +VDYWS G ++HE++TG+RPFLP+++ QWM+ V KTK I ++ ++ F E L P ++ +D E WL+ +L+W P RRGR G++ ++ L +IL++ ++V C + + + +++Q E +TGI Q +L+PNG P ++ + +++ E I++ L+ ++ KL +P + ++PR ++ LQKS ++ A + E Q+ K+ + +++ KIA +K +K E F+ SL D +KY+EQ + + ITS +M + W +S + F N +R E+N ++ + E Q P + P+ ++ +K L L++ E R +++ Q + ++Q+D+ L D F+ L ++ + Q +++L + F +V Q RQ+DLW +L + K K +S ++Q V S + +AS +A + A N + Y+ Sbjct: 8 VEVGTEIDGWIRGPILGHGGFGMVILWKKKDSTETIALKQCRWGHDAMMTPKHKHRWKLEVDIMKRLSHPNVVKALEVPPALDVPETELPLLAMEYCSGGDLRKVLSKSENCCGLNEREVKNLIKHIAAAIKYLHSQRIIHRDLKPENIVLQEMDNKIIYKLIDLGYAKELDQGSLCTSFVGTLQYLAPELFMQNKYSNTVDYWSFGLVAHEVITGQRPFLPHMNTPQWMQHVSNKTKNHIGA-ILDEEGKVMFVEELSPFVKITNIFKKDMEMWLKLMLDWNPFRRGR--EGDMTTYELLDQILNKKVIQVFCTE-SCRLFALEVEDNVSLEEIQVLFESETGIPKNEQEILLPNGSFPDPNKNAVQLWTNPEEGESIVF----LSKKCNFNEFSGTKLCIPPLVARMTRSPRLTMDYELQKSAWTQALYLCHNERTVCQKLLQAYKINVEHIVSINSVTYKAMSKIAIEKNCLSAKVEFFKISLEKDLKKYEEQARNN-GITSNKMHDKWKKSFDLIEKFENLLRKIAHLEINSANAKIKTV--EFQKNPYNHLVLPKHLEDIYQKILDAYHRLKRKTQEQRNIPSDNVEMVQLVCSYIQQKDKVLGDIFSSLVNLKQMKKDIIELQPKLESLALEIQEFSKEVQTAQLMRQNDLWTILEYTI-DKLKMTMPQSSSNQRVTERHSQTSLASFSQQNSFHPQAEPMTSANNSYMDQSYANYL 718
BLAST of IKKbeta vs. nr
Match: gi|1067099801|ref|XP_018011979.1| (PREDICTED: inhibitor of nuclear factor kappa-B kinase subunit beta-like [Hyalella azteca]) HSP 1 Score: 387.497 bits (994), Expect = 2.737e-119 Identity = 247/729 (33.88%), Postives = 375/729 (51.44%), Query Frame = 0 Query: 98 YVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGT-------DVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRNEAG------EIGIFKDLGEILSR--VRVRVVCVDRGGNKLDYILREVTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRVKLTMPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDILGEVNGMVGEIQAIP---KDRPEDMQMFVKKSLQGL--EDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETLAKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQQKQKGDNGRSGN---HQSVSSSPMASIPMPQHQGDEASMILYAENQALRAQLQEYM 803 +V + LG+G FG V +W+++ SG+ +ALKKCR+G + LS +H+E+W++EV I+ RLEHP VV VP +L DLP++CME+CSGGDLRK+LN P +CCGL + V + DL A+ +LH++RIIHRDLKPEN+VLQ +T YKLIDLGYAKEL +S+ SFVGTLQY+APELFLS+ Y+ +VDYWSLG + HEI+TG RPFLPN+SP +WM++V K ICV++ D IHF E +F EN +S L E+WL+ +LEWEP RRG+ E ++ F + +L++ + V VVC VT +D WL ++V L P + P F TL +E L++PR V +LQ+ ++ H+ +F +EN+ + K+ +L LL+R ++ Q++ + ++ LF E+L D + Y Q + +TS + + AW + K Q ++ L +N V E+ P P D + S + L R+ E + D+ + + +++ L++RDR QD + E S V V ++ L+ ++ +S Q+ RQ D+WK++A + G G P+ ++ + Q E + + AEN+ALR Q+ E + Sbjct: 28 WVKEKVLGTGGFGTVTLWKNENSGETVALKKCRWGNTGSPASPETLLSPEHKERWQKEVQIMLRLEHPCVVSCFPVPSELEGGPGDLPILCMEYCSGGDLRKLLNRPENCCGLREVVVRSCLKDLTEAVAYLHSQRIIHRDLKPENIVLQENEGQTRYKLIDLGYAKELEYTSVCTSFVGTLQYLAPELFLSKRYSCTVDYWSLGLVVHEIVTGVRPFLPNMSPVEWMKRVRSKKSCHICVYEGRSGD-IHFSERMFDENHISKPLKSGLEAWLQLMLEWEPARRGQVEGAKPDDKKQVVAFTRMAALLNKKIIGVLVVC-------------GVTNEED--DWL-----LYVFSTCALTPQ---------VAPHFPTL--------------------------------VEEMLRSPRALVEHALQRRMWCHSLYFLYRENKLLSALISAQKIAMLHLLSRHAEVTRCGQRVLNDIAKLQARHHLFMEALNTDLDHYTSQSPQ-ARVTSEKAYGAWRGGGEATLSAVHAAVDKTQRLDAALTALNTKVMELNGSPFSCAKTPTDTLDTIVSSCEELYVSLRRRSRDERSRPHDSTA-MCKLLLQALRKRDRLYQDLYTHIEKQWSCLSEVTALAVPLEELLADIARAAQTISSLQQHRQDDIWKIMAIVASHSRGNVAGAPGGDLPRAPAPPQPLTNLALLLEQSSEQTDNIIAENRALRCQMVELL 692
BLAST of IKKbeta vs. nr
Match: gi|321470783|gb|EFX81758.1| (hypothetical protein DAPPUDRAFT_317376 [Daphnia pulex]) HSP 1 Score: 381.333 bits (978), Expect = 3.460e-117 Identity = 241/729 (33.06%), Postives = 389/729 (53.36%), Query Frame = 0 Query: 95 LGEYVCQTQLGSGSFGVVHVWRHQKSGQILALKKCRFGTDVCLSEKHREQWRQEVDILQRLEHPNVVKSMSVPKDLLRLEEDLPLMCMEFCSGGDLRKMLNMPVHCCGLPQGEVLAITGDLASALGFLHNRRIIHRDLKPENVVLQPTHKRTIYKLIDLGYAKELGQSSLALSFVGTLQYIAPELFLSQEYTKSVDYWSLGFLSHEIMTGRRPFLPNLSPGQWMEQVEKKTKRDICVHQCEDTDEIHFEEHLFPENSLSATLAEDFESWLRSLLEWEPKRRGRN-------EAGEIGIFKDLGEILSRVRVRVVCVDRGGNKLDYILRE--VTKGKDLQTWLERDTGIHVGHQLLLMPNGQEILPEESLLPMFSTLEPNLRIIYCYSSLTGLTMADKIKRVKLT--MPKTLESCLKNPRKEVNRSLQKSIYSHAYFFSSQENRQSLDFDQSLKVLILFLLTRIKDLNGNNQKIAQQKERAISKWELFQESLIHDREKYQEQVKKDVHITSAQMFEAWNQSERDLNDFFNDIRSKRQEVNDI-------LGEVNGMVGEIQAIPKDRPEDMQMFVKKSLQGLEDLRQIPLEGRKEKDTVLDVAQNMVRCLKQRDRNLQDYFNKKETLAKVFSLVRLAQVNVDALIENLDLFMIQVSKCQRKRQSDLWKLLAAALQQKQKGDNGRSGNHQSVSSSPMASIPMPQHQGDEA--SMILYAENQALRAQLQEYM 803 GE+ + LGSG+FG V + ++++G+ +A+KK + W +E+DIL L+HP +V S+ VP DL L D P++CME+C+GGDLR++LN P +CCG+P+ +VL I D++SA+ +LH+ +++HRD+KPENVV+Q T ++ YKLIDLG AK L + SL + VGTLQY+APELF ++Y +VDYWSLG + HE +TG RP LP P WM+ E+KT DIC++ + EI F + LF EN LS+ + E WL+ +LEW P RGR+ G I F L ++L+ V + V+ G L YI+ + VT + + W+ERDTGI +QLL++P G +S F + E L + +S + KLT P+ LE+ L NPR+E +QK +++ + FF + ++ + +LK+ ++ R L I A+S+ +LF SL D+ Y+ Q ++ + S + E WN+ E L++ +++S+ + + + E + G A P ++ +L+ DL++ E +++ + + + + +V+ K R + D F + + K + V + L +D F Q+ Q RQ+D+W LL A+ Q+ + S + +IP + DEA SM++ ENQ+LR Q+Q+ + Sbjct: 13 FGEWKLERLLGSGAFGKVLLMINRQTGEKIAVKKIHRDSPFVADNN----WDKELDILHHLKHPGIVASLPVPPDLRSLSCDAPILCMEYCNGGDLRQVLNKPANCCGIPEMDVLDILRDISSAVVYLHSVKVVHRDIKPENVVIQQTEEKKFYKLIDLGMAKNLNKQSLCHTLVGTLQYLAPELFSCEKYNNTVDYWSLGVVIHECITGVRPVLPGQPPVVWMQHAERKTHSDICIYS-HPSGEIVFSQKLFKENHLSSVVQAQMEEWLKLMLEWNPAMRGRHWVPDASRPPGPIVAFGLLEKVLTTEVVSIFWVE-GLALLSYIVSDDNVTM-ETIHEWIERDTGISPRYQLLVLPRGYASDSGKSARQFFGSEE--LGNVCLFSKFNDGS------ECKLTQVYPEFLETMLANPREEFEYRIQKRMWAQSVFFINHQSTLYRKLNHALKIHSTYMTVRASLLKQQTDFINGALRHAVSRHDLFTSSLKQDQYNYKLQAQRG-GLPSCTLLEKWNKEEFTLSNKLAELQSRCTTLEQVVQRTVSGVAEAAKLAGVFLAKPSVALDNCSQL---ALELYSDLQKRSAEQKQQMENNVAMTKVVVKAFKNRSQLFTDCFTQIRVVEKASADVDSFLPQLIVLKNEIDQFQDQIFVFQTSRQNDVWTLLERAVTLWQR--TSMINQPHAASEPSLLNIPSLSLREDEARESMVVIQENQSLRYQIQDTL 720 The following BLAST results are available for this feature:
BLAST of IKKbeta vs. L. salmonis genes
Analysis Date: 2018-04-19 (T. kinsejongensis vs L. Salmonis peptides) Total hits: 25
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BLAST of IKKbeta vs. SwissProt
Analysis Date: 2018-04-19 (T. kingejongensis peptided Blastp vs. SwissProt) Total hits: 25
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BLAST of IKKbeta vs. nr
Analysis Date: 2018-05-15 (T. kingsejongensis proteins Blastp vs. NR) Total hits: 25
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The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at scaffold168_size293125:130449..133368+ Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>maker-scaffold168_size293125-snap-gene-1.59 ID=maker-scaffold168_size293125-snap-gene-1.59|Name=IKKbeta|organism=Tigriopus kingsejongensis|type=gene|length=2920bp|location=Sequence derived from alignment at scaffold168_size293125:130449..133368+ (Tigriopus kingsejongensis)back to top Synonyms
The feature 'IKKbeta' has the following synonyms
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