Query:    1 LVASRDVKTMEILLEENPCVIGPYVKSPVQCLECFKPIPDVSQAFRCPGCQFPLCGEECSQSKLNHAQDECDQLSGGNLKIQKIPGDNGEKPKKRSKGKKHQETHSMAGSSACNFDYSIITVLRSLRLKERKPEVWNNIMQ-LVDHNHEMAQEGSPTWNLWMTEVIPRLKQFP-GINEQEAL-RFLGIGVTNNANLNLTHGGR---GTSLYPTFARINHQCICNTKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSDPTELGSYLSAFICSKCKSGTVLAQDPLDPESLWICRDCSTSFTVDYLQARLNEILASIDSAHLQTNLIHRYEECLHKFSHTLHPGHQIFTDLNSQLAILYGN-PMYGDLSSWSRPSLDRKIQACQQVLDTNGRVDPGFSAWREKILIELTRTKVHLAQRDLRAGVIGEDKMEEILGEQQFLGIYLGYYRSVL 467
            LVA+RD+K +E++LEE+P VIGPY+ S  QCLECFK +   +    C  C +P C +ECSQ                       P    E    +  G K  E          N  YSIIT LR L L+E KPE WN IM+ ++DHN ++ +     W  +   V+ +++    G  + + L R +G+  TN A+LNL H G+   GT LY  ++ +NH C+CNTK I  +D ++++RAS  I KG++I NQYV+P   T  RR+ +++KWYF+C C RC+DPTE GSYL A +CS CKS  VL  +PL+ ES W C+ CS  + V+Y+   L  +  S++ A       + YE+ L+     LHP H +  +   ++A L GN P         RP+++RK Q C  +L+    VDPGF+ WR +IL ELT+TK++L   D  AG+  + ++ +IL EQQ    YL Y +S+ 
Sbjct:   62 LVATRDIKALEVILEESPLVIGPYISSNNQCLECFKTLD--TSPHSCISCNYPFCSQECSQG----------------------PWHKIECSAFQKYGHKRDEND--------NDFYSIITTLRLLSLQESKPEFWNTIMKDMLDHNSDIQEYTPEKWTSYEETVVKKIQSLTKGNADTDTLTRLIGVIDTNGADLNLPHDGKHGKGTGLYLIYSNLNHSCVCNTKTINFQDRRIEMRASVNISKGEQICNQYVRPNKCTLARRTTIKNKWYFDCCCKRCADPTECGSYLGALLCSSCKS-VVLPINPLETESNWACKGCSKEYDVEYVMGVLISVGESLEEATPYDP--NSYEKILYDTQDLLHPNHYLRIEAELKVAALIGNIPTSSFSKGMPRPAVERKRQCCFHILEVLSLVDPGFNQWRVQILSELTKTKLYLVNIDFNAGLADKVEVFKILQEQQVFQYYLAYNQSIF 500          

Query:    1 LVASRDVKTMEILLEENPCVIGPYVKSPVQCLECFKPIPDVSQAFRCPGCQFPLCGEECSQSKLNHAQDECDQLSGGNLKIQKIPGDNGEKPKKRSKGKKHQETHSMAGSSACNFDYSIITVLRSLRLKERKPEVWNNIMQLVDHNHEMAQEGSPTWNLWMTEVIPRLKQFPG--------------INEQEALRFLGIGVTNNAN---LNLTHGGRGTSLYPTFARINHQCICNTKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSDPTELGSYLSAFICSKCKSGTVLAQDPLDPESLWICRDCSTSFTVDYLQARLNEILASIDSAHLQTNLIHRYEECLHKFSHTLHPGHQIFTDLNSQLAILYGNPMYGDLSSWSRPSLDRKIQACQQVLDTNGRVDPGFSAWREKILIELTRTKVHLAQRDLRAGVIGEDKMEEILG 451
            +VA+RD+  +E++L E P V+GPY K    CL CF+    V  ++ C  C  P+C +EC    L+  + EC      N  I+K                   E H    S AC      +T LR L +K+  P  +  I  L+DH  E         N+ +  +I  LK+                  +++E  R LGI  TN      L    G  G +LYP +  INH C  NT  +K  D  L++R+  PI+KG++I  +YV        RR  ++  W+F+C+C RC D TELG+Y+S   C  CK+G +L  + L+ ES W C +C        +   ++ I + + S   +T  I   EE L+ +   LHP H I  D+   L  +Y         + +RP  +RKIQ C  VL+T GRVDPG++ WR  IL E+    + +++ D     I E +  + L 
Sbjct:  122 MVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRL---VDGSYYCSKCGVPVCDKECEIGDLH--RPECGYFQKNNFVIKK-------------------ENH--YSSQAC------VTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQV-NIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHET--IDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAK-----ETLTRPEKERKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLN 549          

Query:    1 LVASRDVKTMEILLEENPCVIGPYVKSPVQCLECFKPIPDVSQAFRCPGCQFPLCGEECSQSKLNHAQDECDQLSGGNLKIQKIPGDNGEKPKKRSKGKKHQETHSMAGSSACNFDYSIITVLRSLRLKERKPEVWNNIMQLVDHNHE-----MAQEGSPTWNLWMTEVIPRLKQFPGINEQEALRFLGIGVTNNANLNLTHGGRGTSLYPTFARINHQCICNTKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSDPTELGSYLSAFICSKCKSGTVLAQDPLDPESLWICRDCS---TSFTVDYLQARLNEILASIDSAHLQTNLIHRYEECLHKFSHTLHPGHQIFTDLNSQLAILYGNPMYGDLSSWSRPSLDRKIQACQQVLDTNGRVDPGFSAWREKILIELTRTKVHLAQRDLRAGVIGEDKMEEILGE 452
            LVA  D+    ++  E P VIGP   +   CL C   + D    + C  C +P+C   CS S + HA  EC  LS G +K+                        ++      N  Y+ ITVLR+L LK      W   ++   H +E     + Q+ +    ++       LK     ++ E L   G   TN   +    G     LY   + ++H+C  NT+   ++++ + V ++  I+KG+ I   Y +PL  T  RR  L     F C+C RCSDPTE G+YLSAF CS+C  G +L  DPLD +S W C  CS    S TV +    + + L SID  + +       E+ L +++  L   +Q+  ++   L  L+ N    DL +     L RK   C+Q+L    RVDPGFS WR ++L+E+    V L QR L  G I   + ++I  E
Sbjct:  193 LVAKDDISEGSLIFNEPPLVIGPRQLTKAVCLXCHNELKDKKDTYPCRRCTWPMCSRSCSDSPV-HANAECSILSYGGVKV------------------------NIDAFGTANMMYACITVLRALSLK--NDHKWQEYLKFDSHLNERMPTQVYQQVNKEKVVFFIHYF--LKLLSKFSDLEILEACGKLDTNCFEIR-QFGKNLRGLYRIGSIMSHECTPNTRHTFEENYDINVYSTVDIKKGEIICATYTQPLWCTLSRREHLNMSKCFWCRCKRCSDPTEFGTYLSAFSCSEC-GGKMLPLDPLDQKSNWKCEKCSHTLESTTVRHGIESMMDELKSIDRTNPEN-----LEDFLKRYATLLPETNQLTREIQLGLVSLFKNRRNEDLKT---TQLLRKAFMCRQLLTVANRVDPGFSKWRGELLLEMQSANVILGQRALAEGRISNIQAKDIFDE 613          

Query:    1 LVASRDVKTMEILLEENPCVIGPYVKSPVQCLECFKPIPDVSQAFRCPGCQFPLCGEECSQSKLNHAQDECDQLSGGNLKIQKIPGDNGEKPKKRSKGKKHQETHSMAGSSACNFDYSIITVLRSLRLKERKPEVWNNIMQLVDHNHEMAQEGSPTWNLWMTEVIPRLKQFPGINEQEALRF---LGIGVTNNANLNLTHGGRGT------SLYPTFARINHQCICN---TKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSDPTELGSYLSAFICSKCKSGTVLAQDPLDPESLWICRDCSTSFTVDYLQARLNEILASIDSAHLQTNLIHRYEECLHKFSHTLHPGHQIFTDLNSQLAILYGNPMYGDLSSWSRPSLDRKIQACQQVLDTNGRVDPGFSAWREKILIELTRTKVHLAQRDLRAGVIGEDKMEEI 449
            +VA+RD+K  E +L E P   GP   +   CL C+ P+   +Q   C GC FP+C +ECSQ  L H   EC ++   N ++                    Q T    GS      Y+ I+++R+L LK+R P  WN I   + H+   A++    W     + +  +K    I+ ++       LGI + N+  + +   G          ++   +  NH C+ N       +++  K+ ++A   I++G EI++ Y +PL+    R+S+L+   +F+C C RC DPTE+ +Y SA ICSKCK G V++++  +  S W C  C  + + D ++   ++  + I+      + +  +E+ L+K++   HP H    D +  L  +YG     +  S S     RK + C++VL     + PG +  +  ++ EL    V +  R L+ G  G    +EI
Sbjct:   43 MVATRDIKPGETVLMEYPLTFGPGNPNEPICLGCYTPVLK-NQHTECDGCGFPMCSKECSQI-LEHKDFECAEMHNMNFRLDS------------------QNTLKWNGSQESV--YNAISLMRALVLKKRDPARWNLIWMHMSHDE--ARQKDTFWQKKDAKTLEHIKAMMKISPEDYDTIKIILGIFLVNDFEICIPLEGSDEKSSLIRGIFALASMPNHSCVSNCYHNFTCREEGFKMTMKAVVDIKEGDEITHSYTEPLDPIMRRQSLLKIGKFFQCNCIRCRDPTEMSTYSSALICSKCKKGNVISKNCKNINSDWECDSCDLTLSPDSVEQVNSKAKSEIEEMDKNPD-VETHEQFLNKYATIFHPNHVYMIDRSYVLGKMYGRMEGYEPDSLSDDQFMRKKELCERVLKVLNVITPGQTRKKGMMMYELHLPFVIMGNRALQKGPNGNVDPQEI 478          

Query:    1 LVASRDVKTMEILLEENPCVIGPYVKSPVQCLECFKPIPDVSQAFRCPGCQFPLCGEECSQSKLNHAQDECDQLSGGNLKIQKIPGDNGEKPKKRSKGKKHQETHSMAGSSACNFDYSIITVLRSLRLKERKPEVWNNIMQLVDHNHEMAQEGSPTWN-LWMTEVIPRLKQFPGIN--EQEALRFLGIGVTNNANLNLTHGGRGTSLYPTFARINHQCICNTKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSDPTELGSYLSAFICSKCKSGTVLAQDPLDPESLWICRDCSTSFTVDYLQARLNEI---LASIDSAHLQTNLIHRYEECLHKFSHTLHPGHQIFTDLNSQLAILYGNPMYG---DLSSWSRPSLDRKIQACQQVLDTNGRVDPGFSAWREKILIELTRTKVHLAQRDLRAGVIGEDKMEEILGE 452
            L A+RD+K  E++L E P +I P   +P  CL C+ P   V   + CP C +P+C E C  S  +  +       G  +KI         KP                        Y ++ +LR L +KE+  E +  +++L  H  E  + G  + + + M  VI      P     +++ L   GI   N+  + +T      +LY   + + H C+ N       +  + +R + PI+KG+ IS  Y  P+  T  R+  L    +F C+C RC DPTEL ++ S+  C  C +G +++ DP + ES W C  C+   T  ++ A +  I   L S++    +  L       + K S  LHP H    D+   L  + G   YG   ++       L +K + C ++L+   ++ PG S  R  ++ EL       A++    G I  D M+ IL E
Sbjct:   61 LXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAP---VDGRYMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKI----AVTINKPFPL---------------------YEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSP-SQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPAGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSF-----VKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQE 487          

Query:    1 LVASRDVKTMEILLEENPCVIGPYVKSPVQCLECFKPIPDVSQAFRCPGCQFPLCGE-ECSQSKLNHAQDECDQLSGGNLKIQKIPGDNGEKPKKRSKGKKHQETHSMAGSSACNFDYSIITVLRSLRLKERKPEVWNNIMQLVDHNHEMAQEGSPTWNL--WMTEVIPRLKQFPGINE-QEALRFLGIGVTNNANLNLTHGGRGTSLYPTFARINHQCICNTKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSDPTELGSYLSAFIC-------SKCKSGTVLAQDPLDPESLWICRDCSTSFTVDYLQARLNEILASIDSAHLQTNLIHRYEECL-HKFSHTLHPGHQIFTDLNSQLAILYGNPMYGDLSSWSRPSLDRKIQACQQVLDTNGRVDPGFSAWREKILIELTRTKVHLAQRDLRAGVIGEDKMEE 448
            L+ +RD++  E++ EE+P  +GP       CL C+K   +V+    C GC +P+CG  EC ++ + H++ EC  L+  +LK    P  +  KP+K                      Y  +T LR L +KE +P+ W+ +  +  H      E S   N    +  ++ R+K    + +  + +  + +    NA    +H      LYP  A +N  C  NT+    +++  +V A   I KG EI++ Y + L+ T  RR+ L+   YF+CKC RC DPTEL S+ S  +C       SK   G V +++ L+  + WICR C    + + +     ++   I+   L    I  YE  L ++    LHP H I  D    L        Y       R    RK +  + +LD +  + PG+   R  ++ E     + +A  +L      E  +EE
Sbjct:   81 LIVTRDIEPGEVIFEESPITVGPKQFCQPVCLGCYK---NVNGTSICSGCNWPMCGNIECEKAPI-HSKKECALLADCHLK----PIIDLNKPEKDLPI------------------YQFLTALRCLLVKEFRPDNWSILESMESHTELRKNEESYRVNQVNIVKFILERIKYDTTVEDINKCIDVMDV----NAFEIRSHEFSIAGLYPMTAMMNSNCSPNTQNSIDENYICRVMAITRIPKGSEINSTYTRTLSGTLYRRNQLKESKYFDCKCERCCDPTELNSHFSTLLCQAILPSISKTCKGFVYSENSLNTNASWICRACGAVMSHEEVTELTQKLEVEIEKEFLT---IDDYENFLKNRLLKFLHPNHYIIVDFKFILMKALSRAEYDPEIRIQREI--RKKRIIEDILDVHSLITPGYFRIRAMLVSERCMVMMSIAFHNLSNSNKNEIFLEE 505          

Query:  115 FDYSIITVLRSLRLKERKPEVWNNIMQLVDHNHEMAQEGSPTWNLWMTEVIPRLKQFPGINEQEALRFLGIGVTNNANLNLTHGGRGTSLYPTFARINHQCICNTKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSDPTELGSYLSAFICSKCKSGTVLAQDPLDPESLWICRDCSTSFTVDYLQARLNEILASIDSAHLQTNLIHRYEECLHK---FSHTLHPGHQIFTDLNSQLA-ILYGNPMYGDLSSWSRPSLDRKIQACQQVLDTNGRVDPGFSAWREKILIELTRTKVHLAQRDLRAGVI 441
            F+YS I  LR L+LK ++PEVW+ +  L+DH  ++ ++    +   +  ++   K        + LR LGI  TN  N   +   +G  LYPTF+ I+H C  N +    ++H L +RA   I KG+EI+  Y+     T  RR  +++ W F+C C RC DP+E GS LSA  C +C +G +L +   D +S W C +C    +   L    N +L  +   +++  L H   E   K   ++ TL+P + +   LN +L  +L  N  +      +R  L++ +   + +L     ++PG S  R +IL ++ +  + LA+ DL+ G I
Sbjct:  297 FEYSAIFPLRILKLKSKEPEVWSRVNLLMDHVDDLEKDMKSLYEKTVDFILDSCK-LTKYTRSDILRALGIFRTNGVNQGFS---QGFGLYPTFSFISHSCSPNARFQIFENHSLVLRAIQNIPKGEEITISYLPIYQATFRRRIKIKNNWLFDCYCERCKDPSEFGSNLSAVSCKECITGILLPKISTDMKSEWKCSECKYEVSFSSLS---NVML--VFEQNMELFLDHDPLEIQFKIDSWTQTLNPNNYLIFLLNRRLLDVLCTNDNF-----ETREDLEKVLLLARDILKIVDLIEPGLSTTRGRILKQIHKPSLKLAKNDLKDGKI 613          

Query:    1 LVASRDVKTMEILLEENPCVIGPYVKSPV-QCLECFKPIPDVSQAFRCPGCQFPLCGEECSQSKLNHAQDECDQLSGGNLKIQKIPGDNGEKPKKRSKGKKHQETHSMAGSSACNFDYSIITVLRSLRLKERKPEVWNNIMQLVDHNHEMAQEGSPTWNLWMTEVIPRLKQFPGI----NEQEALRFLGIGVTNNANLNLTH---------GGRGTSLYPTFARINHQCICNTKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSDPTELGSYLSAFICSKC-KSGTVLAQDPLDPESLWICRDCSTSFTVDYLQARLNEILASIDSAHLQTNLIHRYEECLHKFSHTLHPGHQIFTDLNSQLAIL-YGNPMYGDLSSWSRPSLDRKIQACQQVLDTNGRVDPGFSAWREKILIELTRTKVHLA 432
            L  +RDVK  ++++   PCVIGP +  P   CL C   I D   +    GC++PLC  EC +    H+++EC  L       +KI     + P KR +                     I+T+LR   LK+  P ++  ++ L DH  E+ +  S  W      V+  LK+         +QE  R +GI +TN+  L  T          G     LY   + +NH C+ N +++      + V A+ PI     I+  Y+ PL +   R+ IL+   +FECKC RC DPTELG++ S+ +C  C KS +   +D  + E    CRDCS   +        N ++   +  H            L ++   L   H     +   L  L   N     +    +     +   C  VL     +DPG S  R  +L EL   +V LA
Sbjct:   62 LRTARDVKQGDLIISAPPCVIGPRLDYPKPSCLGCH-VILDEKMSLCEGGCEYPLCSSECHRK--FHSEEECKLL-------EKI-----KSPDKRCE---------------------IVTILRFALLKKSNPRIYEKLILLEDHVDEI-KASSTRWKNIEEGVLKHLKEIKSDLDIEEDQELERLVGIWITNSFELERTDQQLFGEKRAGESIQGLYDVPSLMNHSCVGNARLVINSGMYIDVYAAVPISNKAPITFNYISPLEDYDRRQKILKENKFFECKCERCEDPTELGTFSSSLLCQVCKKSPSTRTKDSKNYE----CRDCSEVMSERDAMKIANSLMKGKNKLHRIGKAWVTCIPFLKEYQDILWETHTFIIXIKMXLVXLXXSNXAISQMDENGKKIQIERQSYCNDVLAVQDIIDPGMSLGRGLVLHELHAARVFLA 468          

Query:  142 LVDHNHEMAQEGSPTWNLWMTEVIPRLKQFPGINE----QEALRFLGIGVTNNANLNLTHGGRGTSLYPTFARINHQCICNTK-VIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSDPTELGSYLSAFICSKCKSGTVLAQDPLDPESLWICRDCSTSFTVDYLQARLNEILASIDSAHLQT--NLIHRYEECLHKFSHTLHPGHQIFTDLNSQLAILYGNPMYGDLSSWSRPSLDRKIQACQQVLDTNGRVDPGFSAWREKILIELTRTKV 429
            +VDH  +  ++    W  +   ++  L+   G+ E    +E    +GI   N  +L+  +G RG  LYP  A ++H CI NTK +I++KD+  + RA+  I  G E+++ Y+ PL  T  R++ LR  WYF+C+C RC DPTE  + +S+F C+ C  G V     L  E  W C +C TS  + Y  ++++E LA      L+   +L +  EECL   S  L   H +   L   L   Y +         ++  ++R    CQ +LD    V PG +  R   L EL R  +
Sbjct:    1 MVDHIEDKPKD--IHWKAYQKNIVEYLRLSQGLGERFSSEEINHIIGILDVNAFDLSF-NGSRG--LYPLTALMSHSCISNTKYIIRKKDYVAECRATVRILPGXELTDHYISPLLGTESRQACLRDGWYFDCECSRCLDPTEANTQMSSFHCNSCDIGYV--TKSLRGEE-WACLNCGTSSNIPY--SKISEELAGKVENTLRNIPDLENLLEECL---SMRLSSSHYLVLTLKRYLIYAYKSHTL----ILNQEIMERIKGYCQSLLDVVDMVXPGLTKERGLTLYELVRLHI 278          

Query:   20 VIGPYVKSPVQCLECFKPIPDVSQAFR-CPGCQFPLCGEECSQSKLNHAQDECDQLSGGNLKIQKIPGDNGEKPKKRSKGKKHQETHSMAGSSACNFDYSIITVLRSLRLKERKPEVWNNIMQLVDHNHEMAQEGSPTWNLWMTEVIPRLKQFPGINEQEALRFLGIGVTNNANLNL-THGGRGTSLYPTFARINHQCICNTKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSDPTELGSYLSAFICSKCKSGTVLAQDPLDP--ESLWICRDCSTSFTVDYLQARLN---EILASIDSAHLQTNLIHRYEECLHKFSHTLHPGHQIFTDLNSQLAILYGNP---MYGDLSSWSRPSLDRKIQACQQVLDTNGRVDPGFSAWREKILIELTRTKVHLAQRDLRAGVIGEDKMEEILG 451
            V GP   S + CL C+  I D ++    C  C  PLCG+ C +S+LN  + EC  LS                     +GK+     S+A     +  + ++ VLR L L++  PE W++ + L  H  E          L  +E   R      I  +E L   GI  TN+  + L +  G   ++Y       H CI       + D  L +RAS  ++ G  I+  Y   L  T  RR+ L    +F C C RC DPTE GS++ A  C KC  G +L ++PL+   E+ WIC DC       + +   N   +++  ++S  +     +R+   +  +S  L+  H    D+   L  L G+    + GDLS++    L   I  C  +L    ++ PG S  R   L EL  T     QR L     G+ K EEIL 
Sbjct:  430 VHGPCRDSSIVCLNCYGSIQDENEDISVCSRCGLPLCGQ-CDESELNLHKPECHALSSSK------------------RGKRT----SLALLDNVSLLFEVVLVLRCLHLRD-IPENWSHFLGLTSHVGERRDSELEARALEASEXXIRDIGIE-IPREEVLNICGILDTNSFEIPLPSSPGTIQAIYKIGCLPEHNCIPTGHRCFESDLSLVLRASVDLKAGDHITITYTDSLWPTMERRTHLLYSKHFSCICERCRDPTEKGSFIGALNCLKCGVGRILPENPLEDKNETSWICIDCGYVSPQGFAEDTYNQVAQVIQGMESGEINPEQCNRF---ITLYSKILNSQHAHMLDVKHTLLHLLGHHEGYLLGDLSNYLL-QLKEDIARC--LLQVAEKILPGISRLRGTTLYELYLT---YQQRALNWKGEGK-KQEEILA 836          

Query:    1 LVASRDVKTMEILLEENPCVIGPYVKSP--VQCLECFKPIPDVSQAFRCPG-CQFPLCGEECSQSKLNHAQDECDQLSGGNLKIQKIPGDNGEKPKKRSKGKKHQETHSMAGSSACNFDYSIITVLRSLRL-KERKPEVWNNIMQLVDHNHEMAQEGSPTWNLWMTEVIPRLKQFPGINE---QEALRFLGIGVTNNANLNLTHGGRGT---SLYPTFARINHQCICNTKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSDPTELGSYLSAFICSK--CKSGTVLAQD-PLDPESLWICRDCSTSF----TVDYLQARLNEILASIDSAHLQTNLIHRYEECLHKF 354
            + A+RD+   E++ +E   V GP  +      C+ C + +P     F C   C  P+C E CS S+ + A  EC+                  + + +    + ++ + M+          I+T +R   L KE++         LVD    M       +   + +     + FP  +     +  R +G+  TN        GG  T    L+P  A +NH+C  N     +      VRA+  I KG EI+  Y K L     R   L+   +F C C RC D TE G+YLSA  C +  C+   +  Q   L P+  W C  C   F       Y    LN I   I+S  +Q ++IH   E   +F
Sbjct:   69 VFATRDIAAGELIFQERALVTGPTARKGQLSSCICCHETLPQT--GFLCRHRCTLPVC-ETCSDSEEHQA--ECEHF---------------RRWQPKDVDAEQEQVNPMS--------LRILTAVRVFHLGKEQR--------HLVD---AMQANAERAYRREIIQAAQCFRNFPTTDRVFMDQLFRIVGVLNTNAFEAPCRSGGHETLLRGLFPLTAIMNHECTPNASHYFENGRLAVVRAARDIPKGGEITTTYTKILWGNLTRNIFLKMTKHFACDCVRCHDNTENGTYLSALFCREQGCRGLVIPVQTRTLQPD--WRCITCENVFPHAKMAKYQDFALNTINNRINSCSVQ-DMIHFINELCPRF 397          

Query:    1 LVASRDVKTMEILLEENPCVIGPYVKSPVQ---CLECFKPIP-DVSQAFRCP-GCQFPLCGEECSQSKLNHAQDECDQLSGGNLKIQKIPGDNGEKPKKRSKGKKHQETHSMAGSSACNFDYSIITVLRSLRLKERKPEVWNNIMQLVDHNHEMAQEGSPTWNLWMTEVIPRLKQFPGINEQEALRFLGIGVTNNANLNLTHGGRGTSLYPTFARINHQCICNTKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSDPTELGSYLSAFICSK--CKSGTVLAQD-PLDPESLWICRDCSTSF----TVDYLQARLNEILASIDSAHLQTNLIHRYEECLHKF 354
            + A+R++   E L  E+  ++GP     +    C  C++ IP     A  CP GC  P+C E C  S  +    EC                   K  ++ K  + Q     A          I++V+R   L E   ++   +   +D  +   QE     + +  E  PR +       +    F      + +N++  H     +L+P    +NHQC  N     +    + V A+  I  G EI+  Y K L +T  R+  L    +F CKC RC DPTE G+YLSA  C +  C+   +  Q   L P+  W C  C   F       Y    LN I   I+S  +Q ++IH   E   +F
Sbjct:   56 IFATREIAAGEELFREHTLLVGPTAHRSMNLRTCTLCYRLIPGSTDSAALCPAGCGLPVCSE-CRDSTRHDL--EC-------------------KLFRKWKPLESQRIEPRA--------LRILSVVRCFFLDEASRKLLYAMQANMDRYY--MQEVQRAADCF--EHFPREQDMLDYFYRTICAFNTNAFESRSNVD-GHEVLVRALFPLAGLLNHQCTPNAAHHFENGETIVVCATERIPAGAEITMSYAKLLWSTLARKIFLGMTKHFICKCVRCQDPTENGTYLSALFCREQGCRGLVIPVQTRTLQPD--WRCITCENVFPHAKMAKYQDFALNTINNRINSCSVQ-DMIHFINELCPRF 383          

Query:    1 LVASRDVKTMEILLEENPCVIGPY-VKSPVQCLECFKPIPDVSQAFRCPGCQFP-LCGEECSQSKLNHAQDECDQLSGGNLKIQKIPGDNGEKPKKRSKGKKHQETHSMAGSSACNFDYSIITVLRSLRLKERKPEVWNNIMQLVDHNHEMAQEGSPTWNLWMTEVIPRLKQFPGINEQE-ALRFLGIGVTNNANLNLTHGGRGTSLYPTFARINHQCICNTKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSD-----PTELGSYLSAFICSKCKSGTVLAQDPLDPESLWICRDC 314
            L  +RD +  E++L + P +  P    S  +C  CFK     +   +C  CQ    CG  C +S+    +DEC  L+    + +K          +    +  Q    +  ++  N  YS++  L                   V H  E+ ++    +   M  ++  + QFP ++ +E A  F       ++  +     +G  L+P  + INH C  N  ++ ++   + VRA   I K  EI+  Y++   +T  R+  L+ ++ F C+C RCS+       E  + L  + C+  K    L +DP   E  ++C+ C
Sbjct:   25 LFTARDFRPGEVILSQKPYICVPNNTSSESRCDGCFK----TNNLKKCSACQVVWYCGSSCQKSEWKLHRDECKALTRLEKEKRKFVTPTIRLMVRLYIKRNLQNEKVLPITTTDN--YSLVEAL-------------------VSHMSEIDEKQMLLYA-QMANLVNLILQFPSVDLREIAENFSKFSCNAHSICDSELRPQGIGLFPLVSIINHSCSPNAVLVFEEQMAV-VRAMDNISKDSEITISYIETAGSTLTRQKSLKEQYLFHCQCARCSNFGKPHDIEESAILEGYRCANEKCTGFLLRDP--EEKGFVCQKC 317          

Query:  185 IGVTNNANLNLTHGGRGTSLYPTFARINHQCICNTKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRC 274
            + +T   NLN   G     +YP  A INH C  N +   +  H +++ A   I+KG+++   YV PL+   +RR  LR  + F C CPRC
Sbjct:  325 LNLTGTFNLNQIMG----QVYPLVAHINHSCEPNVRYELEPKHGIKLYARKDIKKGEQLRLTYVNPLHGVTLRRRELRVNYGFLCHCPRC 410          

Query:    1 LVASRDVKTMEILLEEN-PCVIGP------YVKSPVQCLECFKPIPDVSQ-----AFRCPGCQFPLCGEECSQSKLNHAQDECDQLSGGNLKIQKIPGDNGEK-------PKKRSKGKKHQETH-SMAGSSACNFDYSIITVLRSLRLKERKPEVWNNIMQLVDHNHEMAQEGSPTWNLWMTEVIPRLKQFPGINE---QEALRFLGIGVTNNANLNLTHGGRGTSLYPTFARINHQCICNTKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSDPTEL 280
            L A+RD++  E+L  E  P  + P       ++S   C  C   + + S         C GC    C   C Q  + H           N  I+ +  +  E+           S G  H  +    A S   N  +  +  + S R++    +  NNI    D      +E +P   LW       ++ FP   E   +  L +LG       ++N   G     LY  ++ +NH C  N +       +L+V A   I+K +E+   YV PL+  ++RR  LR  W F C C RC+   EL
Sbjct:  130 LYATRDIQQGELLFHEKVPIAMVPPMDKLKLIRSGKSCSMCGVSLSNSSHFTMLHGLDCNGCNSIWCSTNCKQKDITHPY--LKHFGSKNKNIRPMDWNMFERHCQENIFVAAYSIGVIHAASLIDKAQSDEINQQFEALAKI-SQRVRYESSDS-NNIGGTFDAEIGSLKEENPE-PLWKKAFDLFIRTFPDTAEMGYEVFLEYLG-----RFHINQLSG----QLYFLYSFLNHNCEPNVRYDINNKLELKVYARKFIKKDEELVTTYVNPLHGVSLRRRELRVNWGFICNCDRCAKEIEL 418          

Query:  134 EVWNNIMQLVDHNHEMAQEGSPTWNLWMTEVIPRLKQFP-GINEQEALRFLGIGVTNNANLNLTHGGRGTSLYPTFARINHQCICNTKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRC 274
            ++ +NI +L +   E  ++ + T+  +M E I    Q P   +  EA  F  +   +    N      G  LYP+ + +NH C  N  ++    H L +RA   IE G+E++  Y+  L  +  RR  LR ++ FEC C RC
Sbjct:  128 DLESNISKLTEDKKEGLRQLAMTFQHFMREEIQDASQLPPSFDLFEA--FAKVICNSFTICNAEMQEVGVGLYPSMSLLNHSCDPNCSIVFNGPH-LLLRAVREIEAGEELTICYLDMLMTSEERRKQLRDQYCFECDCIRC 266          

Query:  134 EVWNNIMQLVDHNHEMAQEGSPTWNLWMTEVIPRLKQFP-GINEQEALRFLGIGVTNNANLNLTHGGRGTSLYPTFARINHQCICNTKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRC 274
            ++ +NI +L +   E  ++   T+  +M E I    Q P   +  EA  F  +   +    N      G  LYP+ + +NH C  N  ++    H L +RA   IE G+E++  Y+  L  +  RR  LR ++ FEC C RC
Sbjct:  128 DLESNINKLTEDKKEGLRQLVMTFQHFMREEIQDASQLPPAFDLFEA--FAKVICNSFTICNAEMQEVGVGLYPSISLLNHSCDPNCSIVFNGPH-LLLRAVRDIEVGEELTICYLDMLMTSEERRKQLRDQYCFECDCFRC 266          

Query:  201 GTSLYPTFARINHQCICNTKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCS----DPT-----ELGSYLSAFICSKCK-SGTVLAQDPLDPESL 308
            G ++ P+ +  NH CI N + ++     +  ++  PI+KG +I+  Y+    +T  RR  L+  +YF C+CPRC+    DPT      L +++S F C + K +G   ++  L  +SL
Sbjct:  265 GMAVSPSSSYFNHSCIPNCESVRDG-SDMTFKSLFPIKKGDQINISYLALDKSTKRRRDYLKFGYYFHCQCPRCNSTDIDPTGKLEDSLDNWISKFYCHQKKCTGLYYSKLKLSLQSL 381          

Query:  201 GTSLYPTFARINHQCICNTKVIKQKDHKLQVRASGPIEKGQEISNQYV--KPLNNTAIRRSILRSKWYFECKCPRCSDPTE---LGSYLSAFICSKCKSGTVLAQDPLDPESLWIC--RDCSTS-FTVDYLQARLNEI 330
             T ++P  + +NH C  NT V         +RAS  I KGQEI + Y   K     A R+  LRS+++F+C CP C         G    AF C+ C +       P+  + +  C  R C+ S  + D+L +RL ++
Sbjct:  528 ATGIFPVISLLNHSCSPNTSV-SFISTVATIRASQRIRKGQEILHCYGPHKSRMGVAERQQKLRSQYFFDCACPACQTEAHRMAAGPRWEAFCCNSCGA-------PMQGDDVLRCGSRSCAESAVSRDHLVSRLQDL 657          

Query:  162 TEVIPRLKQFPGINEQEALRFLG--IGVTNNANLNLTHG----GRGTSLYPTFARINHQCICNTKVI---------KQKDH---KLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSDPTELGSYLSAFICSK-----CKSGTVLAQDPLDP-----------ESLWICRDCSTSFTVDYLQARLNEI-LASIDSAHLQTNLIHRYEECLHKFSHTLHPGHQIFTDLNSQLAILYGNPMYGDLSSW 387
             +V   L+ +P  ++Q +++++    GV N     L+        G  ++P    +NH C  N  VI         K   H   ++++RA G I +G+E++  Y+  L+ +  RR  L+ ++YF+C C  C    +   +L+A    K      K     ++D L+            E + +CR+C       +    L  + L SI S  L  + +  YEE  H     +    +++   N+QL +     M   L++W
Sbjct:  149 VDVDTFLQYWPPQSQQFSMQYISHIFGVINCNGFTLSDQRGLQAVGVGIFPNLGLVNHDCWPNCTVIFNNGNHEAVKSMFHTQMRIELRALGKISEGEELTVSYIDFLHLSEERRRQLKKQYYFDCSCEHCQKGLKDDLFLAAKEDPKPSQEVVKEMIQFSKDTLEKIDKARSEGLYHEVVKLCRECLEKQEPVFADTNLYVLRLLSIASEVL--SYLQAYEEASHYARRMVDGYMKLYHHNNAQLGMAV---MRAGLTNW 404          

Query:    1 LVASRDVKTMEILLEENPCVIGPYVKSPVQCLECFKPIPDVSQAFRCPGCQFPLCGEECSQSKLNHAQDECDQLSGGNLKIQKIPGDNGEKPKKRSKGKKHQETHSMAGSSACNFDYSIITVLRSLRLKERKPEVWNNIMQ-LVDHNHEMAQEGSPTWNLWMTEVIPRLKQFP-GINEQEAL-RFLGIGVTNNANLNLTHGGR---GTSLYPTFARINHQCICNTKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSDPTELGSYLSAFICSKCKSGTVLAQDPLDPESLWICRDCSTSFTVDYLQARLNEILASIDSAHLQTNLIHRYEECLHKFSHTLHPGHQIFTDLNSQLAILYGN-PMYGDLSSWSRPSLDRKIQACQQVLDTNGRVDPGFSAWREKILIELTRTKVHLAQRDLRAGVIGEDKMEEILGEQQFLGIYLGYYRSVL 467
            LVA+RD+K +E++LEE+P VIGPY+ S  QCLECFK +   +    C  C +P C +ECSQ                       P    E    +  G K  E          N  YSIIT LR L L+E KPE WN IM+ ++DHN ++ +     W  +   V+ +++    G  + + L R +G+  TN A+LNL H G+   GT LY  ++ +NH C+CNTK I  +D ++++RAS  I KG++I NQYV+P   T  RR+ +++KWYF+C C RC+DPTE GSYL A +CS CKS  VL  +PL+ ES W C+ CS  + V+Y+   L  +  S++ A       + YE+ L+     LHP H +  +   ++A L GN P         RP+++RK Q C  +L+    VDPGF+ WR +IL ELT+TK++L   D  AG+  + ++ +IL EQQ    YL Y +S+ 
Sbjct:   62 LVATRDIKALEVILEESPLVIGPYISSNNQCLECFKTLD--TSPHSCISCNYPFCSQECSQG----------------------PWHKIECSAFQKYGHKRDEND--------NDFYSIITTLRLLSLQESKPEFWNTIMKDMLDHNSDIQEYTPEKWTSYEETVVKKIQSLTKGNADTDTLTRLIGVIDTNGADLNLPHDGKHGKGTGLYLIYSNLNHSCVCNTKTINFQDRRIEMRASVNISKGEQICNQYVRPNKCTLARRTTIKNKWYFDCCCKRCADPTECGSYLGALLCSSCKS-VVLPINPLETESNWACKGCSKEYDVEYVMGVLISVGESLEEATPYDP--NSYEKILYDTQDLLHPNHYLRIEAELKVAALIGNIPTSSFSKGMPRPAVERKRQCCFHILEVLSLVDPGFNQWRVQILSELTKTKLYLVNLDFNAGLADKVEVFKILQEQQVFQYYLAYNQSIF 500          

Query:    2 VASRDVKTMEILLEENPCVIGPYVKSPVQCLECFKPIPDVSQAFRCPGCQFPLCGEECSQSKLNHAQDECDQLSGGNLKIQKIPGDNGEKPKKRSKGKKHQETHSMAGSSACNFDYSIITVLRSLRLKERKPEVWNNIMQLVDHNHEMAQEGSPTWNLWMTEVIPRLKQF--PGINEQEALRFLGIGVTNNANLNLTHG-GRGTSLYPTFARINHQCICNTKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSDPTELGSYLSAFICSKCK-SGTVLAQDPLDPESLWICRDCSTSFTVDYLQARLNEILASIDSAHLQTNLIHRYEECLHKFSHTLHPGHQIFTDLNSQLAILYGNPMYGDLSSWSRPSLDRKIQACQQVLDTNGRVDPGFSAWREKILIELTRTKVHLAQRDLRAGVIGEDKMEEILGEQQFLGIYLGYYRSVLF 468
            VA  D++ ME+++ E     GPY KS  QCL C +       ++ CPGC+FPLC  EC++ +      EC   S    K                      +  ++   S C   Y+ I V+R   L++  P  ++ +M+   H      E           V+  L +     ++  E  + LG   TN+ ++ L  G GR    YPT+A INH C  NT  ++  D  ++VRA   I KG+EIS QY+  +  T IRR +L  KW FEC C RC+DPTE G+YLSA +C   K  G VL  DP D  S W CR C+T      +   +  I + ID+       I+ YE+ +  +S+ LHP H +   +  +L+ILYGN     L S +RP LDRKIQ C +VLD   ++ PG S+ + KIL EL +T++   +RD+  G++     E IL  ++ L  YL  Y++  F
Sbjct:   54 VAVCDIQPMELIVTEQAVSTGPYTKSIPQCLGCCR---TSCLSYLCPGCRFPLCQVECAEGQ---HMVECKLFSKAGFK---------------------AKIENLTRESPC---YAAIAVIRLFYLRDSNPSAFDQLMKFEHHKERRRLEDLQLTQYHTKYVVDFLIKVCKLKVSASEIFQVLGAMFTNSLDIELPKGYGRENGFYPTYAYINHSCRSNTVTVRFPDKHIEVRAQTLIRKGEEISTQYLDSIKPTFIRRPMLEKKWLFECNCARCTDPTEGGTYLSALLCRTGKCGGAVLPLDPTDGSSEWRCRKCNTEIDTSLVIKIVTSISSQIDNPSPGVQPIYFYEKLISLYSNILHPSHYLNYQMKERLSILYGNIPGFLLKSMTRPQLDRKIQVCLEVLDVQNKLYPGHSSIKIKILGELNKTRLCTVKRDVDHGILLRVCYENILRSEEDLKKYLQLYKTKFF 494          

Query:    1 LVASRDVKTMEILLEENPCVIGPYVKSPVQCLECFKPIPDVSQAFRCPGCQFPLCGEECSQSKLNHAQDECDQLSGGNLKIQKIPGDNGEKPKKRSKGKKHQETHSMAGSSACNFDYSIITVLRSLRLKERKPEVWNNIMQLVDHNHEMAQEGSP-TWNLWMTEVIPRLKQFPGINEQEALRFLGIGVTNNANLNL--THGGRGTSLYPTFARINHQCICNTKVIKQKD-HKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSDPTELGSYLSAFIC--SKCKSGTVLAQDPLDPESLWICRDCSTSFTVDYLQARLNEILASIDSAHLQTNLIHRYEECLHKFSHTLHPGHQIFTDLNSQLAILYGNPMYGDLSSWSRPSLDRKIQACQQVLDTNGRVDPGFSAWREKILIELTRTKV-HLAQRDLRAGVIGEDKMEEIL 450
            LVA++D    +++    P  +GP V+S VQC+ C   + D      C  C  P+C  +C + +  H Q EC  L       QKI          R   K  Q   ++  +   N   +++T+ R   LK R P  WN +  L+DH+      G+P  W   +      L + P   E E  R  GI  TN ANL+L  THG RG  +YP FA +NH C+CN++ ++  + H + V+A   IE G+EIS  Y+KP   T  RR  L +KW F C C RCSDP+ELG++    +C   +C  G +L   PL+  S W C+DC T F+   +   L + L  ++SA      + R EE +      L+  H +   +  +L + Y +   G+    SRP LDR IQ  + +L    R DPG S  R +IL E+  + +     +D + GVI  +K++  +
Sbjct:   54 LVATKDYSPGDVVFALKPATLGPCVRSQVQCVNCLMVLHD---KMTCSKCSLPVCDTKCERGE--HHQAECQVL-------QKI----------RDGLKDQQGGRNLYKAEIKNLTSAVMTI-RLFSLKWRDPGTWNLVSMLMDHD------GNPELWKSILQAYKSILIKDPRFEENELKRVFGIQCTNGANLHLPPTHG-RGVGVYPIFALLNHSCMCNSETLESAESHSVVVKARFKIETGEEISTCYLKPEQATFARRQFLFNKWNFWCSCRRCSDPSELGAFSGGMVCLNGRC-GGLLLPCSPLEEISPWFCQDCRTQFSWHQISNILEQTLLEVESAG-SGGSVERLEELIFTLRQYLYHTHYMLIQVEQRLLLQYWDRSKGNKEKISRPVLDRIIQLSKNILVQQERTDPGESRQR-RILEEIYYSSILERGCKDFKLGVITREKLQNFI 477          

Query:    1 LVASRDVKTMEILLEENPCVIGPYVKSPVQCLECFKPIPDVSQAFRCPGCQFPLCGEECSQSKLNHAQDECDQLSGGNLKIQKIPGDNGEKPKKRSKGKKHQETHSMAGSSACNFDYSIITVLRSLRLKERKPEVWNNIMQLVDHNHEMAQEGSPTWNLWMTEVIPRLKQFPGI----NEQEALRFLGIGVTNNANLNLTHGGRG--TSLYPTFARINHQCICNTK-VIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSDPTELGSYLSAFICSKCKSGTVLAQDPLDP-ESLWICRDCSTSFTVDYLQARLNEILASIDSAHLQTNLIHRYEECLHKFSHTLHPGHQIFTDLNSQLAILYGNPMYGDLSSWSRPSLDRKIQACQQVLDTNGRVDPGFSAWREKILIELTRTKVHLAQRDLRAG 439
            LVA+R++K  EI+  EN  ++GP       CL+CF  +  V+  FRCPGC FP C E+C++S  + A  EC  LS     I                        S+   S  +  Y  IT LR + LK  +P+++     LV HN    Q  +  W ++   ++  L+   G+    +E+E     G+   N   + L    R     L+P  + ++H+C+ NT  VI    +++ VRAS PI+KG+++   Y  PL+ T  RRS+LR    FEC CPRCSDPTE  ++LSA  C +C  G +L   PL+  E+ W C  CS       +   ++++    +  ++    + + EE L + + +LHP H +FT +   L+ LYG      L++ +   L+RK+  CQQ+L     V+PG +  R   L EL    + LA+R   AG
Sbjct:   61 LVATRNLKPGEIIFGENATIVGPKQGCRPCCLKCFTSLDSVASLFRCPGCNFPFCQEQCAKSPEHEA--ECVVLSRARSCI------------------------SINDMSKSHPVYQCITPLRCILLKSTQPKLFEAFSGLVHHNDLRRQ--TQMWRIYQVNIVQFLRNVCGLANQFSEEEIHAACGVLDVNAFEIRLPGSKRQQVLGLFPIASMMSHRCVSNTHHVIDSNTYEMTVRASVPIKKGEQLFTTYTLPLDGTNDRRSVLRQSKMFECDCPRCSDPTECLTFLSALRCPRCPIGIMLPIRPLEENETEWQCSPCSYQLDAADVTQLIDQLKEEFE--NIGPKDVEKLEEFLSRHASSLHPNHFLFTSVRQSLSQLYGRDERYLLNTLTMEQLERKVSICQQLLSVADVVEPGLTRLRGVTLYELYAPMLLLAKRTYEAG 477          

Query:    1 LVASRDVKTMEILLEENPCVIGPYVKSPVQCLECFK----PIPDVSQAFRCPGCQFPLCGEECSQSKLNHAQDECDQLSGGNLKIQKIPGDNGEKPKKRSKGKKHQETHSMAGSSACNFDYSIITVLRSLRLKERKPEVWNNIMQLVDHNHEMAQEGSPTWNLWMTEVIPRLKQFPGINE---QEALRFLGIGVTNNANLNLTHGGRGT-SLYPTFARINHQCICNTKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSDPTELGSYLSAFICSKCKSGTVLAQDPLDPESLWICRDCSTSFTVDYLQARLNEILASIDSAHLQTNLIHRYEECLHKFSHTLHPGHQIFTDLNSQLAILYGNPMYGDLSSWSRPSLDRKIQACQQVLDTNGRVDPGFSAWREKILIELTRTKVHLAQRDLRAGVIGEDKMEEILGE 452
            L A+RD+K  EI L E P + GP V S   CL C +    P+P     ++C  C +PLCG +C  S   H  DEC+ +S    K  KI  D    P K   GKK                Y +I  LR + L+ + PE +    QL DH +E  +  +P + +    ++  +K   G +E    E LR      TN   +     G+   ++Y   A I+H C+ N +       ++   A   I KG+ I+  Y +PL +T +RR  L     FEC C RC DP ELG++  A +CS+CK G +++ DPLD  +LW C+ C        +      +L  I+S  L       +EE LH++  TLH  +     +   L  LYGN     +   +  ++ RK++ CQ++L+    +D G+S +R  +L++L    V  A+R+  +G++ +  ++E L E
Sbjct:   59 LRATRDIKKGEIFLREKPFIYGPKVASAPTCLGCHRSLPNPVPPQKNFYKCSRCSWPLCGPQCENSA--HHIDECELMSARKFK-AKIDFD----PTKEGTGKKESA-------------YCVILPLRCILLRNKNPEAFARFAQLEDHLNE--RMNTPLYRILSANLLTFIKTIMGFSEWSDDEVLRVAARLDTNTFEVRQAAAGQKLRAIYTNAAMISHDCVSNARHTFDDQMQILFIAKQKIAKGEIIATSYTQPLKSTLMRRQHLSQAKCFECTCARCKDPEELGTFAGAILCSRCKVGKIISTDPLDNGALWKCQLCPHEIPAKQINWGNGAMLKEIES--LNKMSPRAFEEFLHRYRDTLHEKNTHVLQVKYALTQLYGNAPGFQMHEMNDAAVKRKVELCQELLEVAEILDGGWSIFRGNLLLDLQEALVVQAKREFESGLLTKANVQEKLTE 494          

Query:    1 LVASRDVKTMEILLEENPCVIGPYVKSPVQCLECFK----PIPDVSQAFRCPGCQFPLCGEECSQSKLNHAQDECDQLSGGNLKIQKIPGDNGEKPKKRSKGKKHQETHSMAGSSACNFDYSIITVLRSLRLKERKPEVWNNIMQLVDHNHEMAQEGSPTWNLWMTEVIPRLKQFPGINE---QEALRFLGIGVTNNANL-NLTHGGRGTSLYPTFARINHQCICNTKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSDPTELGSYLSAFICSKCKSGTVLAQDPLDPESLWICRDCSTSFTVDYLQARLNEILASIDSAHLQTNLIHRYEECLHKFSHTLHPGHQIFTDLNSQLAILYGNPMYGDLSSWSRPSLDRKIQACQQVLDTNGRVDPGFSAWREKILIELTRTKVHLAQRDLRAGVIGEDKMEEILGE 452
            L A+RD+K  EI L E P + GP V S   CL C +    P P  +  ++C  C +PLCG +C +S   H  DEC+ ++      +K        P K   GKK                Y +I  LR + LK + PE +    QL DH +E  ++ +P + +    ++  +K   G +E   ++ LR      TN   +  +  G +  ++YP  A I+H C+ N +        +   A   I KG+ I+  Y +PL  T +RR  L     FEC C RCSDP EL ++  A +CSKCK G +++ +PLD  +LW C+ C        +      ++  I+S + ++  +  +EE LH++  TLH  +     +   L  LYGN     +   +  ++ RK++ CQ++LD    +D GFS +R  +L++L    V  A+R+   G++ +  ++E L E
Sbjct:   59 LRATRDIKKGEIFLREKPFIYGPKVASAPTCLGCHRTLQAPEPPQTNFYKCTRCSWPLCGPQCERS--THHIDECELMTA-----RKFNAKIDYNPNKEQTGKKESA-------------YCVILPLRCILLKNKNPEAFARFSQLEDHLNE--RKDTPLYKILGANLLTFIKTVMGFSEWSDEDVLRVAARLDTNAFEVRQVATGQKLRAIYPNAAMISHDCVSNARHTFDAQMHILFIAKQKIAKGEIIATSYTQPLKCTLMRRQHLLQTKCFECTCKRCSDPEELSTFAGAILCSKCKIGKIISTNPLDNAALWKCQLCPHEIPAKQINWGNGAMVKEIESLNKKSPRV--FEEFLHRYRDTLHEKNTHVLQVKYALTQLYGNAPGFQMHEMNDAAVKRKVELCQELLDIADILDGGFSIFRGNLLLDLQEALVVQAKREFEQGLLTKTNVQEKLAE 494          

Query:    1 LVASRDVKTMEILLEENPCVIGPYVKSPVQCLECFK----PIPDVSQAFRCPGCQFPLCGEECSQSKLNHAQDECDQLSGGNLKIQKIPGDNGEKPKKRSKGKKHQETHSMAGSSACNFDYSIITVLRSLRLKERKPEVWNNIMQLVDHNHEMAQEGSPTWNLWMTEVIPRLKQFPGINE---QEALRFLGIGVTNNANLNLTHGGRGT-SLYPTFARINHQCICNTKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSDPTELGSYLSAFICSKCKSGTVLAQDPLDPESLWICRDCSTSFTVDYLQARLNEILASIDSAHLQTNLIHRYEECLHKFSHTLHPGHQIFTDLNSQLAILYGNPMYGDLSSWSRPSLDRKIQACQQVLDTNGRVDPGFSAWREKILIELTRTKVHLAQRDLRAGVIGEDKMEEILGE 452
            L A+RD+K  EI L E P + GP V S   CL C +    P+P     ++C  C +PLCG +C  S  +H  DEC+ +S    K  KI  D    P K   GKK                Y +I  LR + L+ + PE +    QL D+ +E  +  +P + +    ++  +K   G +E    E LR      TN   +     G+   ++Y   A I+H C+ N +       ++   A   I KG+ I+  Y +PL +T +RR  L     FEC C RC DP ELG++  A +CS+CK G +++ DPLD  +LW C+ C        +      +L  I+S  L       +EE LH++  TLH  +     +   L  LYGN     +   +  ++ RK++ CQ++L+    +D G+S +R  +L++L    V  A+R+   G++ +  ++E L E
Sbjct:   59 LRATRDIKKGEIFLREKPFIYGPKVASTPTCLGCHRSLPNPVPPQKNFYKCSRCSWPLCGPQCENS--SHHIDECELMSARKFK-AKIDFD----PTKEGTGKKESA-------------YCVILPLRCILLRNKNPEAFARFAQLEDNLNE--RLNTPLYRILSANLLTFIKTIMGFSEWSDDEVLRVAARLDTNTFEVRQAAAGQKLRAIYTNAAMISHDCVSNARHTFDDQMQILFIAKQKIAKGEIIATSYTQPLKSTLMRRQHLSQAKCFECTCARCKDPEELGTFAGAILCSRCKVGKIISTDPLDNGALWKCQLCPHEIPAKQINWGNGAMLKEIES--LNKTSPRAFEEFLHRYRDTLHEKNTHVLQVKYALTQLYGNAPGFQMHEMNDAAVKRKVELCQELLEVADILDGGWSIFRGNLLLDLQEALVVQAKREFERGLLTKANVQEKLTE 494          

Query:    1 LVASRDVKTMEILLEENPCVIGPYVKSPVQCLECFKPIPDVSQAFRCPGCQFPLCGEECSQSKLNHAQDECDQLSGGNLKIQKIPGDNGEKPKKRSKGKKHQETHSMAGSSACNFDYSIITVLRSLRLKERKPEVWNNIMQLVDHNHEMAQEGSPTWNLWMTEVIPRLKQFPGINE----QEALRFLGIGVTNNANLNLTHGGRGTSLYPTFARINHQCICN-TKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSDPTELGSYLSAFICSKCKSGTVLAQDPLDPESLWICRDCSTSFTVDYLQARLNEILASIDSAHLQTNL-------IHRYEECLHKFSHTLHPGHQIFTDLNSQLAILYGNPMYGDLSSWSRPSLDRKIQACQQVLDTNGRVDPGFSAWREKILIELTRTKVHLAQRDLRAGVIGEDKMEEILGE 452
            LVA++D+ + E++  + P  +GP   +P  CL C+ P+ +      C  C +P+C EEC +S   HA  EC+  S   +K Q +       P+                          IT LR L  KE+ P+ W   +++++  H   ++  PTW      +   L  +  + +    +   +  GI   N+  +    G    +LYP  A   H C+ N    I Q D+++QVRA+ P+++G+ ++  Y   L+ T +RR  L    +FEC C RC+DPTELG++LS   CSKC +G +LA +PLD E+ W C D +  F      A + ++LA + S   Q ++       I + E  ++K+    HP H +   L   LA LYG      +       L+RK + C+ VL T   + PG +  R  +L EL    + LA+ +  AG+I ++K++E L E
Sbjct:   20 LVANKDLVSGELIFTDTPFAVGPKPDTPPLCLSCYCPVENT----LCSACGWPVCSEECGKSP-AHA-GECEVFSAVKVKFQTVEDWTVSAPQ-----------------------LDCITPLRILLAKEKDPDRWQRELEVME-THTKERKERPTWGADQVNIADFLVDYCKLGDRFDRELVQKVCGILEVNSVEIPSRGGFSIRALYPQLAIAAHNCVPNIVHTILQNDYQVQVRAAVPLKQGETLNICYTHSLSPTIVRRDFLLESKFFECDCARCADPTELGTHLSTLKCSKCDNGVILATNPLDNEAPWTCTDKNCGFKTS--GAAMRKMLAVVQSEIDQLDMMEPGPAAIEQREATINKYKSVFHPRHSLLLSLKHTLAQLYGRVEGYSIDELPDLMLERKAEFCRLVLSTLDVIMPGETRMRGMMLYELHAPLMFLARNEFSAGLITQEKLKEKLQE 451          

Query:    1 LVASRDVKTMEILLEENPCVIGPYVKSPVQCLECFKPIPD----VSQAFRCPGCQFPLCGEECSQSKLNHAQDECDQLSGGNLKIQKIPGDNGEKPKKRSKGKKHQETHSMAGSSACNFDYSIITVLRSLRLKERKPEVWNNIMQLVDHNHEMAQEGSPTWNLWMTEVIPRLKQFPGINE---QEALRFLGIGVTNNANLNLTHGGRGT-SLYPTFARINHQCICNTKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSDPTELGSYLSAFICSKCKSGTVLAQDPLDPESLWICRDCSTSFTVDYLQARLNEILASIDSAHLQTNLIHRYEECLHKFSHTLHPGHQIFTDLNSQLAILYGNPMYGDLSSWSRPSLDRKIQACQQVLDTNGRVDPGFSAWREKILIELTRTKVHLAQRDLRAGVIGEDKMEEILGE 452
            L A+RD+K  EI L E P + GP V S   CL C + +P+     +  ++C  C +PLCG +C +S L+   DEC+ ++    K  KI  D    P K   GKK                Y +I  LR + L+ + PE +    QL DH +E  +  +P + +    ++  +K   G +E    + LR      TN   +     G+   S+Y   A I+H C+ N +       ++   A   I KG+ I+  Y +PL  T +RR  L     FEC C RC DP ELG++  A +CS+CK G +++ +PLD  +LW C+ C        +      +L  I+S + Q+     +EE LH++  TLH  +     +   L  LYGN     +   +  ++ RK++ CQ++L+    +D G S +R  +L++L    V  A+R+   G++ +  ++E L E
Sbjct:   59 LRATRDIKKGEIFLREKPFIYGPKVASAPTCLGCHRSLPNPVSPKNNFYKCSRCSWPLCGPQCEKSSLH--IDECELMAARKFK-AKIDYD----PTKEGTGKKESA-------------YCVILPLRCILLRNKNPEAFARFAQLEDHLNE--RINTPLYKILSANLLTFIKTIMGFSEWSDDDVLRIAARLDTNTFEVRQAATGQKLRSIYTHAAMISHDCVSNARHTFDDQMQILFIAKQKIAKGEVIATSYTQPLKCTLMRRQHLSQAKCFECTCARCKDPEELGTFAGAILCSRCKIGKIISTNPLDNGALWKCQLCPHEIPAKQINWGNGAMLKEIESLNKQSP--RAFEEFLHRYRDTLHEKNTHMLQVKYALTQLYGNAPGFQMHEMNDAAVKRKVELCQELLEVAEILDGGASIFRGNLLLDLQEALVVQAKREFEKGLLTKANVQEKLTE 494          

Query:    1 LVASRDVKTMEILLEENPCVIGPYVKSPVQCLECFKPIPDVSQAFRCPGCQFPLCGEECSQSKLNHAQDECDQLSGGNLKIQKIPGDNGEKPKKRSKGKKHQETHSMAGSSACNFDYSIITVLRSLRLKERKPEVWNNIMQLVDHNHEMAQEGSPTW-NLWMTEVIPRL-KQFPG--INEQEALRFLGIGVTNNANLNLTHGGRGTSLYPTFARINHQCICNTKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSDPTELGSYLSAFICSKCKSGTVLAQDPLDPESLWICRDCSTSFTVDYLQARLNEILASIDSAH------LQTNLIHRYEECLHKFSHTLHPGHQIFTDLNSQLAILYGNPMYGDLSSWSRPSLDRKIQACQQVLDTNGRVDPGFSAWREKILIELTRTKVHLAQRDLR 437
            LVA+ D+K  E++L+E P V+ P + S   CLEC +   +   A  C  C+FP+C +EC Q   NH Q EC  L+        +P     KP +RS                 N  +++I V+R L L+E  P++ +    L+DH  ++  +GSP   N+W    + +L ++ P     +++ LR +G+  TN+    +   GRG +LYPTF+  NH CICN++     D  + +RA   I KG EI+ QY+ PL  T  RR  +R  W+F C C RC+DPTE G++LS  IC  C+   VL  +PLD E+ W C  CS   T   +QA +N + A +DS        LQT            ++  LH  H +F  L   +           L   +R  L+ ++   +Q +     +DPG +  R +++      K+ LA  DL+
Sbjct:   59 LVATADIKPGEVILQEYPAVVAPSLVSATVCLECLR---NWQGANLCSKCKFPVCNKECEQGT-NHKQ-ECSVLA-------LLPTAPTFKPDERS-----------------NPAFALIGVIRFLFLQE-NPDLADRTSLLMDHVDDI--KGSPDLLNMWEGTAVQQLVRELPNSKYTKEDVLRAVGVLHTNS----VAGMGRGHALYPTFSLTNHSCICNSRFQIYPDRSILLRAQVSIPKGSEITTQYLTPLIGTMPRRQKIRKNWFFSCICDRCADPTEKGTFLSGIICQSCQD-IVLPANPLDYETTWKCMKCSVETTGATVQALMNSLQADLDSTDPADFDALQTK--------RKNWAKVLHQNHYLFLQLKRNILGCLKMLPEARLEQQNRKRLELQVALAEQNIQVFDVLDPGLTILRGRMIQHCNGPKLQLANMDLK 460