EMLSAG00000000123, EMLSAG00000000123-682889 (gene) Lepeophtheirus salmonis
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Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of EMLSAG00000000123 vs. GO
Match: - (symbol:Vav "Vav ortholog (H. sapiens)" species:7227 "Drosophila melanogaster" [GO:0005085 "guanyl-nucleotide exchange factor activity" evidence=ISS] [GO:0019992 "diacylglycerol binding" evidence=ISS] [GO:0005575 "cellular_component" evidence=ND] [GO:0008360 "regulation of cell shape" evidence=IMP] [GO:0007155 "cell adhesion" evidence=IMP] [GO:0007015 "actin filament organization" evidence=IMP] [GO:0016477 "cell migration" evidence=IMP] [GO:0007391 "dorsal closure" evidence=IMP] [GO:0030676 "Rac guanyl-nucleotide exchange factor activity" evidence=IDA] [GO:0007424 "open tracheal system development" evidence=IMP] [GO:0032864 "activation of Cdc42 GTPase activity" evidence=IDA] [GO:0007411 "axon guidance" evidence=IMP] [GO:0032863 "activation of Rac GTPase activity" evidence=IDA] [GO:0007520 "myoblast fusion" evidence=IMP] [GO:0031532 "actin cytoskeleton reorganization" evidence=IDA] [GO:0007417 "central nervous system development" evidence=IGI] [GO:0007409 "axonogenesis" evidence=IMP] [GO:0072499 "photoreceptor cell axon guidance" evidence=IMP] [GO:0035011 "melanotic encapsulation of foreign target" evidence=IMP] Pfam:PF00017 InterPro:IPR000219 InterPro:IPR000980 InterPro:IPR001452 InterPro:IPR001715 InterPro:IPR002219 InterPro:IPR028530 Pfam:PF00130 Pfam:PF00307 Pfam:PF00621 PROSITE:PS00479 PROSITE:PS50001 PROSITE:PS50002 PROSITE:PS50010 PROSITE:PS50021 PROSITE:PS50081 SMART:SM00033 SMART:SM00109 SMART:SM00252 SMART:SM00325 SMART:SM00326 InterPro:IPR001849 GO:GO:0007264 Gene3D:2.30.29.30 Gene3D:3.30.505.10 InterPro:IPR011993 SMART:SM00233 PROSITE:PS50003 GO:GO:0046872 GO:GO:0007391 GO:GO:0008360 EMBL:AE014298 GO:GO:0007155 GO:GO:0007417 SUPFAM:SSF50044 GO:GO:0016477 GO:GO:0072499 GO:GO:0031532 Gene3D:1.20.900.10 SUPFAM:SSF48065 Gene3D:1.10.418.10 SUPFAM:SSF47576 GO:GO:0007520 GO:GO:0007015 GO:GO:0030676 GO:GO:0032863 GO:GO:0007424 GO:GO:0035011 eggNOG:NOG326494 KO:K05730 PANTHER:PTHR22826:SF53 GeneTree:ENSGT00740000115307 OrthoDB:EOG78SQH7 EMBL:AF218780 EMBL:AY069536 EMBL:AY095173 EMBL:BT029984 RefSeq:NP_573372.1 RefSeq:NP_728235.1 UniGene:Dm.218 ProteinModelPortal:Q9NHV9 SMR:Q9NHV9 PaxDb:Q9NHV9 PRIDE:Q9NHV9 EnsemblMetazoa:FBtr0074677 EnsemblMetazoa:FBtr0074678 GeneID:32920 KEGG:dme:Dmel_CG7893 UCSC:CG7893-RA CTD:32920 FlyBase:FBgn0040068 InParanoid:Q9NHV9 SignaLink:Q9NHV9 GenomeRNAi:32920 NextBio:781038 Bgee:Q9NHV9 Uniprot:Q9NHV9) HSP 1 Score: 213.772 bits (543), Expect = 1.053e-57 Identity = 202/722 (27.98%), Postives = 319/722 (44.18%), Query Frame = 0
Query: 17 GNTQSFNMVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKR--SSVPGF-----PKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTLLSSKDK-ELIFYKLDELIRLHTEILTGL------NIKGSQVGEIFLRL-NPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK------------------------NSEMIIDI------VIHCLGKIDVVEKT------IKLMQLPRGAQLSDFGRLRKAGEL--TAENSYGARLSDYAFLFDTIILL--CTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHP---NSIPLFHRIVPHPTPHLLFV--CRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGSTNSNASSINNNGLTKCDSVTLPTVINEPLERSESTLSLSPDSKQPSADRVSKLQRETEEELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVRKR 678
G N LW+ECVAWL KVIPP HK Q ++++ +RDGVLLC LV LDPSS+D R P+ + F+C NI LFL +NF + D FEP LY N V+ TLS LS C KV++ + GF P + H ++E IY K+++ + Y+ T E +YQ +CA R S SS S +RD I ELIDTE YL+ L ++ F L ++D+ LIF ++ EL+ +HT+ L L N K ++ ++FL P + +YG++C L ++D++ + K++ + + C+ L L +P QR LK E +ID+ V + +++K I L+Q G+ L +GRL GEL A +L YAF+FD I+++ K +Y +R + + DYR+ Q+ ++ + ++ + F ++ +R+ WRKA+T+A++ +EP H + + TF T+C C++ + G QGYRC+ CQ +HK C I++ G K + V++P P DR + +WFAG+++ +TA+ RL++ +GT+L+R R
Sbjct: 11 GGVAGVNGDLWRECVAWLTRCKVIPPDHKAAQP--DAEIRILAMTLRDGVLLCNLVIHLDPSSLD-PREFNRKPQ------MAQFLCSKNIKLFLDVCHNNFGIR-DADLFEPTMLYDLTNFHRVLITLSKLSQCRKVQQLHPDLIGFNLQLSPTERSH------SDEAIY---KDLHSTTTDNIACNGTG---YDHTNTKEEEVYQDLCA--LHRTSRSQTASS-TSFEQRDYVIRELIDTESNYLDVLTALKTKFMGPLERHLNQDELRLIFPRIRELVDIHTKFLDKLRESLTPNAK-VKMAQVFLDFREPFL--IYGEFCSLLLGAIDYLADVCKKNQIIDQLVQKCERDYNVGKLQLRDILSVPMQRILKYHLLLDKLVKETSPLHDDYRSLERAKEAMIDVSQYINEVKRDSDHLVIIQKVKDSICDIHLLQNGNGSDLLQYGRLLLDGELHIKAHEDQKTKLR-YAFVFDKILIMVKALHIKTGDMQYTYRDSHNLADYRVEQSHSRRTIGRDTRFKYQLLLARKSGKTAFTLYLKSEHERDKWRKALTEAMESLEPPGCQSTDHKMEIYTFDAPTTCRHCSKFLKGRIHQGYRCKVCQISVHKGC------------------ISSTGRCKQNPVSVPP---------------------PVCDR---------------QLSEFNWFAGNMDRETAAHRLENRRIGTYLLRVR 649
BLAST of EMLSAG00000000123 vs. GO
Match: - (symbol:VAV2 "Uncharacterized protein" species:9031 "Gallus gallus" [GO:0005089 "Rho guanyl-nucleotide exchange factor activity" evidence=IEA] [GO:0005154 "epidermal growth factor receptor binding" evidence=IEA] [GO:0005737 "cytoplasm" evidence=IEA] [GO:0005886 "plasma membrane" evidence=IEA] [GO:0007264 "small GTPase mediated signal transduction" evidence=IEA] [GO:0016477 "cell migration" evidence=IEA] [GO:0030032 "lamellipodium assembly" evidence=IEA] [GO:0043552 "positive regulation of phosphatidylinositol 3-kinase activity" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] Pfam:PF00017 Pfam:PF00169 InterPro:IPR000219 InterPro:IPR000980 InterPro:IPR001331 InterPro:IPR001452 InterPro:IPR001715 InterPro:IPR002219 InterPro:IPR028530 Pfam:PF00130 Pfam:PF00621 PRINTS:PR00401 PRINTS:PR00452 PROSITE:PS00479 PROSITE:PS00741 PROSITE:PS50001 PROSITE:PS50002 PROSITE:PS50010 PROSITE:PS50021 PROSITE:PS50081 SMART:SM00033 SMART:SM00109 SMART:SM00252 SMART:SM00325 SMART:SM00326 InterPro:IPR001849 GO:GO:0005886 GO:GO:0005737 GO:GO:0007264 Gene3D:2.30.29.30 Gene3D:3.30.505.10 InterPro:IPR011993 SMART:SM00233 PROSITE:PS50003 GO:GO:0046872 SUPFAM:SSF50044 GO:GO:0016477 GO:GO:0005089 Gene3D:1.20.900.10 SUPFAM:SSF48065 Gene3D:1.10.418.10 SUPFAM:SSF47576 GO:GO:0030032 GO:GO:0032319 InterPro:IPR011511 Pfam:PF07653 InterPro:IPR022613 Pfam:PF11971 GO:GO:0043552 OMA:WFAGNME OrthoDB:EOG73FQKZ TreeFam:TF316171 PANTHER:PTHR22826:SF53 GeneTree:ENSGT00740000115307 EMBL:AADN03007369 Ensembl:ENSGALT00000004255 PRO:PR:F1NG51 Uniprot:F1NG51) HSP 1 Score: 206.453 bits (524), Expect = 3.925e-55 Identity = 155/603 (25.70%), Postives = 281/603 (46.60%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYL-NTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYN--DTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTL-LSSKDKELIFYKLDELIRLHTEILTGLNIK----GSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHC--------------------------------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARLSD-YAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPL----FHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGST 581
M W++C WL + KV+PP H+++ ++ + D +RDGVLLCQL+H+L P S+D+ + + SQ F+C NI FL F L N+D F+P DL+ ++ G VI +S LS + + + FP +E +N++++Y S++E+ + + +DIY+ +D ++IY+ I + Q + + KR+ + E+ +TE KY + L + + + L L L+ +D E IF L++LI++H L +++ GS + ++FL + +YG YC H+ + + + L +R ++ C K + F L L++P QR LK ++ +++ H L KI + +I+ +Q+ +L +FGR + GEL + D Y FLFD ++++C R + Y + +++ +++ P + I F+ I F C+ + W + A+ ++P++ H M TF++ T+C C + G F+QGY C +C A HK+C+ P ++GS+
Sbjct: 1 MEEWRQCGRWLIDCKVLPPNHRVVWP--SAVVFDLAQALRDGVLLCQLLHNLSPGSIDLKDINFRPQMSQ-------FLCLKNIRTFLKVCHDKFGLRNSD--LFDPFDLFDVRDFGKVISAVSRLSFHSIAQTKGIRPFPSEET-----TENDDDVYRSLEELADEHD-------LGEDIYDCVPCEDEGDDIYEDIIRVEVQ----QPMKMGMTEDDKRNCCLLEIQETEAKYYKTLEDIEKNYMNPLKLVLTPQDMEAIFINLEDLIKVHFNFLRAIDVSMMSGGSSLAKVFLEFKERLL-IYGKYCSHMEYAQNTLNHLIANRDDVRQKVEECTLKVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSSDRPEKQQLKEALEAMQDLAMYINEVKRDKETLKKISEFQSSIENLQV----KLEEFGRPKIDGELKVRSIVNHTKQDRYLFLFDKVVIVCKRKGY---NYELKEIIELLFHKM-TDDPMNNKDIKKWSYGFYLIHLQGKQGFQFFCKTEEMKRKWMEQFEMAMSNIKPEKANANHHSFQMYTFEKTTNCKACKMFLRGTFYQGYLCPKCGAGAHKECLEIIPPCKMGSS 567
BLAST of EMLSAG00000000123 vs. GO
Match: - (symbol:Vav2 "vav 2 guanine nucleotide exchange factor" species:10116 "Rattus norvegicus" [GO:0005085 "guanyl-nucleotide exchange factor activity" evidence=ISO] [GO:0005089 "Rho guanyl-nucleotide exchange factor activity" evidence=IEA] [GO:0005154 "epidermal growth factor receptor binding" evidence=IEA;ISO] [GO:0005622 "intracellular" evidence=ISO] [GO:0005737 "cytoplasm" evidence=IEA;ISO] [GO:0005886 "plasma membrane" evidence=IEA;ISO] [GO:0007264 "small GTPase mediated signal transduction" evidence=IEA;ISO] [GO:0016477 "cell migration" evidence=IEA;ISO] [GO:0030031 "cell projection assembly" evidence=ISO] [GO:0030032 "lamellipodium assembly" evidence=IEA;ISO] [GO:0043087 "regulation of GTPase activity" evidence=ISO] [GO:0043552 "positive regulation of phosphatidylinositol 3-kinase activity" evidence=IEA;ISO] [GO:0046872 "metal ion binding" evidence=IEA] Pfam:PF00017 Pfam:PF00169 InterPro:IPR000219 InterPro:IPR000980 InterPro:IPR001331 InterPro:IPR001452 InterPro:IPR001715 InterPro:IPR002219 InterPro:IPR028530 Pfam:PF00130 Pfam:PF00621 PRINTS:PR00401 PRINTS:PR00452 PROSITE:PS00479 PROSITE:PS00741 PROSITE:PS50001 PROSITE:PS50002 PROSITE:PS50010 PROSITE:PS50021 PROSITE:PS50081 SMART:SM00033 SMART:SM00109 SMART:SM00252 SMART:SM00325 SMART:SM00326 InterPro:IPR001849 RGD:1306285 GO:GO:0005886 GO:GO:0005737 GO:GO:0007264 Gene3D:2.30.29.30 Gene3D:3.30.505.10 InterPro:IPR011993 SMART:SM00233 PROSITE:PS50003 GO:GO:0046872 SUPFAM:SSF50044 GO:GO:0016477 GO:GO:0005089 Gene3D:1.20.900.10 SUPFAM:SSF48065 Gene3D:1.10.418.10 SUPFAM:SSF47576 GO:GO:0030032 GO:GO:0032319 InterPro:IPR011511 Pfam:PF07653 InterPro:IPR022613 Pfam:PF11971 GO:GO:0043552 CTD:7410 KO:K05730 OMA:WFAGNME OrthoDB:EOG73FQKZ TreeFam:TF316171 PANTHER:PTHR22826:SF53 GeneTree:ENSGT00740000115307 EMBL:AABR06022030 EMBL:AABR06022031 EMBL:AABR06022032 RefSeq:NP_001100033.2 UniGene:Rn.98555 ProteinModelPortal:D3ZYG0 Ensembl:ENSRNOT00000009893 GeneID:296603 KEGG:rno:296603 UCSC:RGD:1306285 NextBio:35571122 PRO:PR:D3ZYG0 Uniprot:D3ZYG0) HSP 1 Score: 201.83 bits (512), Expect = 1.451e-53 Identity = 177/728 (24.31%), Postives = 304/728 (41.76%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYN--DTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQL-TLLSSKDKELIFYKLDELIRLHTEILTGLNIK----GSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHC--------------------------------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARLSD-YAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPL----FHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCI-------------GDYPCLEVGSTNSNASSINNN---------GLTKCDSVTL-------PTVINEPLERSESTLSLSPDSKQPSADRVSKLQRETEEELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVRKR 678
M W++C WL + KV+PP H+++ ++ + D +RDGVLLCQL+H+L P S+D+ + + SQ F+C NI FL F L E F+P DL+ ++ G VI +S LS + + + FP +E +N++++Y S++E+ + + +DIY+ +D ++IY+ I + Q + L KR + E+ +TE KY L + + L +LS D IF L++LI++H L +++ GS + ++FL + +YG+YC H+ + + L R ++ C K + F L L++P QR LK ++ +++ H L KI + +I+ +Q+ +L +FGR + GEL + D Y FLFD ++++C R + Y + +++ +++ P H I F+ I F C+ + W + A+ ++P + H M TF + T+C C + G F+QGY C RC HK+C+ D P +G + + N D + L P ++ +S S K D + R E I WFAG++ + L+S GT+L+R+R
Sbjct: 1 MEQWRQCGRWLIDCKVLPPNHRVVWP--SAVVFDLAQALRDGVLLCQLLHNLSPGSIDLKDINFRPQMSQ-------FLCLKNIRTFLKVCHDKFGLRNSE-LFDPFDLFDVRDFGKVISAVSRLSLHSIAQSKGIRPFPSEET-----AENDDDVYRSLEELADEHD-------LGEDIYDCVPCEDEGDDIYEDIIKVEVQ----QPMKMGLTEDDKRSCCLLEIQETEAKYYRTLEDIEKNYMGPLRQVLSPVDMATIFINLEDLIKVHHSFLRAIDVSMMAGGSTLAKVFLEFKERLL-IYGEYCSHMEHAQSALNQLLASRDDFRQKVEECTLKVQEGKFKLQDLLVVPMQRVLKYHLLLKELLSHSADRPERQQLKEALEAMQDLAMYINEVKRDKETLKKISEFQCSIENLQV----KLEEFGRPKIDGELKVRSIVNHTKQDRYLFLFDKVVIVCKRKG---YSYELKEVIELLFHKM-TDDPMHNKDIKKWSYGFYLIHLQGKQGFQFFCKTEDMKRKWMEQFEMAMSNIKPDKANANHHSFQMYTFDKTTNCKACKMFLRGTFYQGYLCTRCGVGAHKECLEVIPPCKMSSPADADAPGAGLGPKMVAVQNYHGNPAPPGKPVLTFQTGDVIELLRGDPDSPWWEGRLVQTRKSGYFPSSSVKPCPVDGRPPVGRPPSRE---IDYTAYPWFAGNMERQQTDNLLKSHASGTYLIRER 690
BLAST of EMLSAG00000000123 vs. GO
Match: - (symbol:Vav2 "vav 2 oncogene" species:10090 "Mus musculus" [GO:0001525 "angiogenesis" evidence=IEA] [GO:0005085 "guanyl-nucleotide exchange factor activity" evidence=ISO;IMP] [GO:0005089 "Rho guanyl-nucleotide exchange factor activity" evidence=IEA] [GO:0005154 "epidermal growth factor receptor binding" evidence=IPI] [GO:0005515 "protein binding" evidence=IPI] [GO:0005622 "intracellular" evidence=IMP] [GO:0005737 "cytoplasm" evidence=IDA] [GO:0005886 "plasma membrane" evidence=IDA] [GO:0007264 "small GTPase mediated signal transduction" evidence=IMP] [GO:0016477 "cell migration" evidence=IGI] [GO:0030031 "cell projection assembly" evidence=IGI] [GO:0030032 "lamellipodium assembly" evidence=IGI] [GO:0035023 "regulation of Rho protein signal transduction" evidence=IEA] [GO:0035556 "intracellular signal transduction" evidence=IEA] [GO:0043087 "regulation of GTPase activity" evidence=ISO;IMP] [GO:0043552 "positive regulation of phosphatidylinositol 3-kinase activity" evidence=IGI] [GO:0046872 "metal ion binding" evidence=IEA] Pfam:PF00017 Pfam:PF00169 InterPro:IPR000219 InterPro:IPR000980 InterPro:IPR001331 InterPro:IPR001452 InterPro:IPR001715 InterPro:IPR002219 InterPro:IPR028530 Pfam:PF00130 Pfam:PF00621 PRINTS:PR00401 PRINTS:PR00452 PROSITE:PS00479 PROSITE:PS00741 PROSITE:PS50001 PROSITE:PS50002 PROSITE:PS50010 PROSITE:PS50021 PROSITE:PS50081 SMART:SM00033 SMART:SM00109 SMART:SM00252 SMART:SM00325 SMART:SM00326 InterPro:IPR001849 MGI:MGI:102718 GO:GO:0005829 GO:GO:0005886 GO:GO:0007264 Gene3D:2.30.29.30 Gene3D:3.30.505.10 InterPro:IPR011993 SMART:SM00233 PROSITE:PS50003 GO:GO:0046872 GO:GO:0001525 SUPFAM:SSF50044 GO:GO:0016477 GO:GO:0005089 Gene3D:1.20.900.10 SUPFAM:SSF48065 GO:GO:0005085 Gene3D:1.10.418.10 SUPFAM:SSF47576 GO:GO:0030032 GO:GO:0032319 InterPro:IPR011511 Pfam:PF07653 InterPro:IPR022613 Pfam:PF11971 GO:GO:0043552 CTD:7410 eggNOG:NOG326494 HOVERGEN:HBG018066 KO:K05730 OMA:WFAGNME OrthoDB:EOG73FQKZ TreeFam:TF316171 ChiTaRS:VAV2 PANTHER:PTHR22826:SF53 EMBL:U37017 EMBL:AL731552 EMBL:AL772282 RefSeq:NP_033526.1 UniGene:Mm.179011 ProteinModelPortal:Q60992 SMR:Q60992 IntAct:Q60992 MINT:MINT-85279 STRING:10090.ENSMUSP00000062782 PhosphoSite:Q60992 PaxDb:Q60992 PRIDE:Q60992 DNASU:22325 Ensembl:ENSMUST00000056176 GeneID:22325 KEGG:mmu:22325 UCSC:uc008ixh.1 GeneTree:ENSGT00740000115307 HOGENOM:HOG000234364 InParanoid:Q60992 NextBio:302553 PRO:PR:Q60992 Bgee:Q60992 CleanEx:MM_VAV2 Genevestigator:Q60992 Uniprot:Q60992) HSP 1 Score: 200.29 bits (508), Expect = 4.248e-53 Identity = 152/601 (25.29%), Postives = 268/601 (44.59%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYN--DTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTL-LSSKDKELIFYKLDELIRLHTEILTGLNIK----GSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHC--------------------------------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARLSD-YAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPL----FHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGS 580
M W++C WL + KV+PP H+++ ++ + D +RDGVLLCQL+H+L P S+D+ + + SQ F+C NI FL F L E F+P DL+ ++ G VI +S LS + + + FP +E +N++++Y S++E+ + + +DIY+ +D ++IY+ I + Q + + KR + E+ +TE KY L + + L L LS D +F L++LI++H L +++ GS + ++FL + +YG+YC H+ + + L R ++ C + + F L L++P QR LK ++ +++ H L KI + +I+ +Q+ +L +FGR + GEL + D Y FLFD ++++C R + Y + +++ +++ P H I F+ I F C+ + W + A+ ++P + H M TF + T+C C + G F+QGY C RC HK+C+ P ++ S
Sbjct: 1 MEQWRQCGRWLIDCKVLPPNHRVVWP--SAVVFDLAQALRDGVLLCQLLHNLSPGSIDLKDINFRPQMSQ-------FLCLKNIRTFLKVCHDKFGLRNSE-LFDPFDLFDVRDFGKVISAVSRLSLHSIAQSKGIRPFPSEET-----AENDDDVYRSLEELADEHD-------LGEDIYDCVPCEDEGDDIYEDIIKVEVQ----QPMKMGMTEDDKRSCCLLEIQETEAKYYRTLEDIEKNYMGPLRLVLSPADMAAVFINLEDLIKVHHSFLRAIDVSMMAGGSTLAKVFLEFKERLL-IYGEYCSHMEHAQSTLNQLLASREDFRQKVEECTLRVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSADRPERQQLKEALEAMQDLAMYINEVKRDKETLKKISEFQCSIENLQV----KLEEFGRPKIDGELKVRSIVNHTKQDRYLFLFDKVVIVCKRKG---YSYELKEVIELLFHKM-TDDPMHNKDIKKWSYGFYLIHLQGKQGFQFFCKTEDMKRKWMEQFEMAMSNIKPDKANANHHSFQMYTFDKTTNCKACKMFLRGTFYQGYLCTRCGVGAHKECLEVIPPCKMSS 566
BLAST of EMLSAG00000000123 vs. GO
Match: - (symbol:VAV2 "Guanine nucleotide exchange factor VAV2" species:9606 "Homo sapiens" [GO:0001525 "angiogenesis" evidence=IEA] [GO:0005085 "guanyl-nucleotide exchange factor activity" evidence=EXP;TAS] [GO:0005089 "Rho guanyl-nucleotide exchange factor activity" evidence=IEA] [GO:0005154 "epidermal growth factor receptor binding" evidence=IEA] [GO:0005515 "protein binding" evidence=IPI] [GO:0005829 "cytosol" evidence=TAS] [GO:0005886 "plasma membrane" evidence=IEA] [GO:0007165 "signal transduction" evidence=TAS] [GO:0007264 "small GTPase mediated signal transduction" evidence=TAS] [GO:0007411 "axon guidance" evidence=TAS] [GO:0007596 "blood coagulation" evidence=TAS] [GO:0016477 "cell migration" evidence=IEA] [GO:0030032 "lamellipodium assembly" evidence=IEA] [GO:0030168 "platelet activation" evidence=TAS] [GO:0038095 "Fc-epsilon receptor signaling pathway" evidence=TAS] [GO:0038096 "Fc-gamma receptor signaling pathway involved in phagocytosis" evidence=TAS] [GO:0043065 "positive regulation of apoptotic process" evidence=TAS] [GO:0043087 "regulation of GTPase activity" evidence=EXP;TAS] [GO:0043552 "positive regulation of phosphatidylinositol 3-kinase activity" evidence=IEA] [GO:0045087 "innate immune response" evidence=TAS] [GO:0046872 "metal ion binding" evidence=IEA] [GO:0048011 "neurotrophin TRK receptor signaling pathway" evidence=TAS] [GO:0051056 "regulation of small GTPase mediated signal transduction" evidence=TAS] [GO:0097190 "apoptotic signaling pathway" evidence=TAS] Reactome:REACT_604 Pfam:PF00017 Pfam:PF00169 InterPro:IPR000219 InterPro:IPR000980 InterPro:IPR001331 InterPro:IPR001452 InterPro:IPR001715 InterPro:IPR002219 InterPro:IPR028530 Pfam:PF00130 Pfam:PF00307 Pfam:PF00621 PRINTS:PR00401 PRINTS:PR00452 PROSITE:PS00479 PROSITE:PS00741 PROSITE:PS50001 PROSITE:PS50002 PROSITE:PS50010 PROSITE:PS50021 PROSITE:PS50081 SMART:SM00033 SMART:SM00109 SMART:SM00252 SMART:SM00325 SMART:SM00326 InterPro:IPR001849 GO:GO:0005829 GO:GO:0005886 Reactome:REACT_111045 Reactome:REACT_111102 Reactome:REACT_6900 GO:GO:0007411 GO:GO:0038095 GO:GO:0045087 GO:GO:0048011 GO:GO:0007264 GO:GO:0030168 Gene3D:2.30.29.30 Gene3D:3.30.505.10 InterPro:IPR011993 SMART:SM00233 PROSITE:PS50003 GO:GO:0046872 EMBL:CH471090 GO:GO:0097190 GO:GO:0001525 GO:GO:0043065 GO:GO:0038096 SUPFAM:SSF50044 GO:GO:0016477 GO:GO:0005089 Gene3D:1.20.900.10 SUPFAM:SSF48065 GO:GO:0005085 Gene3D:1.10.418.10 SUPFAM:SSF47576 GO:GO:0030032 GO:GO:0032319 PDB:2LNW PDBsum:2LNW InterPro:IPR011511 Pfam:PF07653 EMBL:AL445931 GO:GO:0043552 EMBL:AL590710 EMBL:S76992 EMBL:AL357934 EMBL:BC033187 EMBL:BC132965 EMBL:BC132967 EMBL:BX640754 EMBL:AY563001 PIR:I51940 RefSeq:NP_001127870.1 RefSeq:NP_003362.2 RefSeq:XP_005272270.1 UniGene:Hs.369921 UniGene:Hs.689325 PDB:2DLZ PDB:2DM1 PDB:2LNX PDBsum:2DLZ PDBsum:2DM1 PDBsum:2LNX ProteinModelPortal:P52735 SMR:P52735 BioGrid:113253 DIP:DIP-33088N IntAct:P52735 MINT:MINT-1494337 PhosphoSite:P52735 DMDM:212287930 PaxDb:P52735 PRIDE:P52735 Ensembl:ENST00000371850 Ensembl:ENST00000371851 Ensembl:ENST00000406606 GeneID:7410 KEGG:hsa:7410 UCSC:uc004cer.3 UCSC:uc004ces.3 CTD:7410 GeneCards:GC09M136627 HGNC:HGNC:12658 HPA:HPA003224 MIM:600428 neXtProt:NX_P52735 PharmGKB:PA37281 eggNOG:NOG326494 HOVERGEN:HBG018066 InParanoid:P52735 KO:K05730 OMA:WFAGNME OrthoDB:EOG73FQKZ TreeFam:TF316171 SignaLink:P52735 ChiTaRS:VAV2 EvolutionaryTrace:P52735 GeneWiki:VAV2 GenomeRNAi:7410 NextBio:29012 PRO:PR:P52735 Bgee:P52735 Genevestigator:P52735 PANTHER:PTHR22826:SF53 Uniprot:P52735) HSP 1 Score: 199.904 bits (507), Expect = 7.485e-53 Identity = 177/733 (24.15%), Postives = 310/733 (42.29%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYN--DTQDNYENIYQTICAPKTQRFSLEIFGS-SLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTL-LSSKDKELIFYKLDELIRLHTEILTGLNIK----GSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHC--------------------------------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARLSD-YAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRI-------GQTSPSHPNSIPL-FHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDY-PCLEVGSTNSNASSI----------NNNG---------LTKCDSVTLPTVINEP---------LERSESTLSLSPDSKQPSADRVSKLQRETEEELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVRKR 678
M W++C WL + KV+PP H+++ ++ + D +RDGVLLCQL+H+L P S+D+ + + SQ F+C NI FL F L E F+P DL+ ++ G VI +S LS + + + FP +E +N++++Y S++E+ + + +DIY+ +D ++IY+ I + Q+ + + KR+ + E+ +TE KY L + + L L LS D +F L++LI++H L +++ GS + ++FL + +YG+YC H+ + + + L R ++ C K + F L L++P QR LK ++ +++ H L KI + +I+ +Q+ +L +FGR + GEL + D Y FLFD ++++C R + Y + +++ +++ SH F+ I F C+ + W + A+ ++P + H M TF + T+C C + G F+QGY C +C HK+C+ PC + +AS N +G LT L + +P ++ +S S K D + R E I WFAG++ + L+S GT+L+R+R
Sbjct: 1 MEQWRQCGRWLIDCKVLPPNHRVVWP--SAVVFDLAQALRDGVLLCQLLHNLSPGSIDLKDINFRPQMSQ-------FLCLKNIRTFLKVCHDKFGLRNSE-LFDPFDLFDVRDFGKVISAVSRLSLHSIAQNKGIRPFPSEET-----TENDDDVYRSLEELADEHD-------LGEDIYDCVPCEDGGDDIYEDIIKVEVQQPMIRYMQKMGMTEDDKRNCCLLEIQETEAKYYRTLEDIEKNYMSPLRLVLSPADMAAVFINLEDLIKVHHSFLRAIDVSVMVGGSTLAKVFLDFKERLL-IYGEYCSHMEHAQNTLNQLLASREDFRQKVEECTLKVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSAERPERQQLKEALEAMQDLAMYINEVKRDKETLRKISEFQSSIENLQV----KLEEFGRPKIDGELKVRSIVNHTKQDRYLFLFDKVVIVCKRKG---YSYELKEIIELLFHKMTDDPMNNKDVKKSHGKMWSYGFYLIHLQGKQGFQFFCKTEDMKRKWMEQFEMAMSNIKPDKANANHHSFQMYTFDKTTNCKACKMFLRGTFYQGYMCTKCGVGAHKECLEVIPPCKFTSPADLDASGAGPGPKMVAMQNYHGNPAPPGKPVLTFQTGDVLELLRGDPESPWWEGRLVQTRKSGYFPSSSVKPCPVDGRPPISRPPSRE---IDYTAYPWFAGNMERQQTDNLLKSHASGTYLIRER 700
BLAST of EMLSAG00000000123 vs. GO
Match: - (symbol:VAV1 "Proto-oncogene vav" species:9913 "Bos taurus" [GO:0005089 "Rho guanyl-nucleotide exchange factor activity" evidence=IEA] [GO:0035556 "intracellular signal transduction" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] Pfam:PF00018 Pfam:PF00017 Pfam:PF00169 InterPro:IPR000219 InterPro:IPR000980 InterPro:IPR001331 InterPro:IPR001452 InterPro:IPR001715 InterPro:IPR002219 InterPro:IPR028530 Pfam:PF00130 Pfam:PF00621 PRINTS:PR00401 PRINTS:PR00452 PROSITE:PS00479 PROSITE:PS00741 PROSITE:PS50001 PROSITE:PS50002 PROSITE:PS50010 PROSITE:PS50021 PROSITE:PS50081 SMART:SM00033 SMART:SM00109 SMART:SM00252 SMART:SM00325 SMART:SM00326 InterPro:IPR001849 GO:GO:0007264 Gene3D:2.30.29.30 Gene3D:3.30.505.10 InterPro:IPR011993 SMART:SM00233 PROSITE:PS50003 GO:GO:0046872 SUPFAM:SSF50044 GO:GO:0005089 Gene3D:1.20.900.10 SUPFAM:SSF48065 Gene3D:1.10.418.10 SUPFAM:SSF47576 GO:GO:0032319 InterPro:IPR011511 Pfam:PF07653 InterPro:IPR003096 PRINTS:PR00888 InterPro:IPR022613 Pfam:PF11971 eggNOG:NOG326494 HOVERGEN:HBG018066 KO:K05730 PANTHER:PTHR22826:SF53 EMBL:BC123646 RefSeq:NP_001071542.1 UniGene:Bt.21717 UniGene:Bt.47442 ProteinModelPortal:Q08DN7 SMR:Q08DN7 STRING:9913.ENSBTAP00000050922 PRIDE:Q08DN7 GeneID:617345 KEGG:bta:617345 CTD:7409 HOGENOM:HOG000203247 InParanoid:Q08DN7 NextBio:20900612 Uniprot:Q08DN7) HSP 1 Score: 181.415 bits (459), Expect = 8.337e-47 Identity = 183/729 (25.10%), Postives = 306/729 (41.98%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDA--ETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGL-----NIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIH----------------------CLGKIDVVEKTIKLM---QLP---RGAQLSDFGRLRKAGELTAEN-SYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPLFHRIV-----PHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDY-PCLEVGSTNSNA------------SSINNNGLTKCDSVTLPTVINEPLERSESTLSLSP----------------DSKQPSADRVSKLQRETEEELINIPVERQS---WFAGDLNPKTASVRLQSLPVGTFLVRKR 678
M LW++C WL +V+PP H++ T +++ + +RDGVLLCQL+++L P ++++ V SQ F+C NI FL F L E FE DL+ Q+ G VI TLSALS + + FP +E +E+IYS + + D E E +YD + + + YE++ ++ P + + KR + E+ TE+KY + L ++ F L L +D E+IF +++L+R+HT L + N S + ++F++ +YG YC + + + + ++ +L C +A F L L++P QR LK ++ ++V H C+ ++ +T++ + QL L+ +GR + GEL + +++ YAFL D +L+C R Y + V + +++ S ++ H + L F R + W + A+ + P+ GH M +F+E TSC C ++ G F+QGYRCQRC+A HK+C+G PC G S N GL K + + P L L+P + + S + V + ++ P + S W+AG + A L + GTFLVR+R
Sbjct: 1 MELWRQCTHWLIQCRVLPPSHRV--TWDGAQVCELAQALRDGVLLCQLLNNLLPHAINLREVNLRPQMSQ-------FLCLKNIRTFLSTCYEKFGLKRSE-LFEAFDLFDVQDFGKVIYTLSALSWTPIAQNKGIMPFPTEES------VGDEDIYSGLSDQIDDTVEEDEDLYDCVENE-EAEGDEVYEDLMRSEPVPMPPKMT---------EYDKRCCCLREIQQTEEKYTDTLGSIQQHFMKPLQRFLKPQDVEIIFINIEDLLRVHTHFLKEMKEALANPGASTLYQVFIKYKERFL-IYGRYCSQVESASKHLDRVATAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQDAMEKDNLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLAHYGRPKIDGELKITSVERRSKMDRYAFLLDKALLICKRRG---DTYDLKDFVNLHSFQVRDDSSGERDNKKWTHMFLLIEDQGAQGYELFFKTRELKKK--WMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCQRCRAPAHKECLGRVPPCGRHGQDYSGTMKKDKPHRRAQDKKRNELGLPKMEVCQEYYGLPPPPGAIGPFLRLNPGDIVELTKAEAEQNWWEGRNISTNEVGWFPCNRVKPYVHGPPQDLSVHLWYAGPMERAGAESILTNRSDGTFLVRQR 697
BLAST of EMLSAG00000000123 vs. GO
Match: - (symbol:Vav1 "Proto-oncogene vav" species:10116 "Rattus norvegicus" [GO:0005089 "Rho guanyl-nucleotide exchange factor activity" evidence=IEA] [GO:0043087 "regulation of GTPase activity" evidence=TAS] [GO:0046872 "metal ion binding" evidence=IEA] Pfam:PF00018 Pfam:PF00017 Pfam:PF00169 InterPro:IPR000219 InterPro:IPR000980 InterPro:IPR001331 InterPro:IPR001452 InterPro:IPR001715 InterPro:IPR002219 InterPro:IPR028530 Pfam:PF00130 Pfam:PF00621 PRINTS:PR00401 PRINTS:PR00452 PROSITE:PS00479 PROSITE:PS00741 PROSITE:PS50001 PROSITE:PS50002 PROSITE:PS50010 PROSITE:PS50021 PROSITE:PS50081 SMART:SM00033 SMART:SM00109 SMART:SM00252 SMART:SM00325 SMART:SM00326 InterPro:IPR001849 RGD:3951 GO:GO:0007264 Gene3D:2.30.29.30 Gene3D:3.30.505.10 InterPro:IPR011993 SMART:SM00233 PROSITE:PS50003 GO:GO:0046872 SUPFAM:SSF50044 GO:GO:0005089 Gene3D:1.20.900.10 SUPFAM:SSF48065 GO:GO:0005085 Gene3D:1.10.418.10 SUPFAM:SSF47576 GO:GO:0032319 InterPro:IPR011511 Pfam:PF07653 InterPro:IPR003096 PRINTS:PR00888 GO:GO:0048468 InterPro:IPR022613 Pfam:PF11971 GO:GO:0002768 HOVERGEN:HBG018066 PANTHER:PTHR22826:SF53 EMBL:U39476 UniGene:Rn.48861 ProteinModelPortal:P54100 SMR:P54100 PRIDE:P54100 Genevestigator:P54100 Uniprot:P54100) HSP 1 Score: 181.03 bits (458), Expect = 1.412e-46 Identity = 157/593 (26.48%), Postives = 264/593 (44.52%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDA--ETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGLNIKGSQVG-----EIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIH----------------------CLGKIDVVEKTIKLM---QLP---RGAQLSDFGRLRKAGELTAENSYGARLSD-YAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPLFHRIV-----PHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYP 574
M LW++C WL +V+PP H++ T +++ + +RDGVLLCQL+++L P ++++ V SQ F+C NI FL F L E FE DL+ Q+ G VI TLSALS + + FP ++ L +E+IYS + + D E E +YD + + + YE++ ++ P + + KR + E+ TE+KY + L ++ F L L +D E IF ++EL+ +HT L L S G ++F++ +YG YC + ++ + + ++ +L C +A F L L++P QR LK ++ ++V H C+ ++ +T++ + QL L+++GR + GEL + +D YAFL D +L+C R Y + +V + +++ S ++ H + L F R + W + A+ + P+ GH M +F+E TSC C ++ G F+QGYRC RC+A HK+C+G P
Sbjct: 1 MELWRQCTHWLIQCRVLPPSHRV--TWEGAQVCELAQALRDGVLLCQLLNNLLPHAINLREVNLRPQMSQ-------FLCLKNIRTFLSTCCEKFGLKRSE-LFEAFDLFDVQDFGKVIYTLSALSWTPIAQNKGIMPFPTEDSALG-----DEDIYSGLSDQIDDTAEEDEDLYDCVENE-EAEGDEIYEDLMRSESVPTPPKMT---------EYDKRCCCLREIQQTEEKYTDTLGSIQQHFMKPLQRFLKPQDMETIFVNIEELLSVHTHFLKELKDALSGPGATMLYQVFIKYKERFL-VYGRYCSQVESAIKHLDQVATAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQDTTEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLANYGRPKIDGELKITSVERRSKTDRYAFLLDKALLICKRRG---DSYDLKASVNLHSFQVRDDSSGERDNKKWSHMFLLIEDQGAQGYELFFKTRELKKK--WMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCYRCRAPAHKECLGRVP 562
BLAST of EMLSAG00000000123 vs. GO
Match: - (symbol:Vav1 "vav 1 guanine nucleotide exchange factor" species:10116 "Rattus norvegicus" [GO:0002768 "immune response-regulating cell surface receptor signaling pathway" evidence=IEP] [GO:0005085 "guanyl-nucleotide exchange factor activity" evidence=ISO;TAS] [GO:0005089 "Rho guanyl-nucleotide exchange factor activity" evidence=IEA;ISO] [GO:0005622 "intracellular" evidence=ISO] [GO:0006909 "phagocytosis" evidence=IEA;ISO] [GO:0006955 "immune response" evidence=IEA;ISO] [GO:0007186 "G-protein coupled receptor signaling pathway" evidence=ISO] [GO:0007229 "integrin-mediated signaling pathway" evidence=IEA;ISO] [GO:0030217 "T cell differentiation" evidence=ISO] [GO:0030593 "neutrophil chemotaxis" evidence=ISO] [GO:0030676 "Rac guanyl-nucleotide exchange factor activity" evidence=IEA;ISO] [GO:0032314 "regulation of Rac GTPase activity" evidence=ISO] [GO:0032855 "positive regulation of Rac GTPase activity" evidence=ISO] [GO:0035556 "intracellular signal transduction" evidence=IEA;ISO] [GO:0042110 "T cell activation" evidence=IEA;ISO] [GO:0043087 "regulation of GTPase activity" evidence=ISO;TAS] [GO:0045785 "positive regulation of cell adhesion" evidence=IEA;ISO] [GO:0046872 "metal ion binding" evidence=IEA] [GO:0048468 "cell development" evidence=TAS] [GO:0072593 "reactive oxygen species metabolic process" evidence=ISO] Pfam:PF00018 Pfam:PF00017 Pfam:PF00169 InterPro:IPR000219 InterPro:IPR000980 InterPro:IPR001331 InterPro:IPR001452 InterPro:IPR001715 InterPro:IPR002219 InterPro:IPR028530 Pfam:PF00130 Pfam:PF00621 PRINTS:PR00401 PRINTS:PR00452 PROSITE:PS00479 PROSITE:PS00741 PROSITE:PS50001 PROSITE:PS50002 PROSITE:PS50010 PROSITE:PS50021 PROSITE:PS50081 SMART:SM00033 SMART:SM00109 SMART:SM00252 SMART:SM00325 SMART:SM00326 InterPro:IPR001849 RGD:3951 GO:GO:0007264 Gene3D:2.30.29.30 Gene3D:3.30.505.10 InterPro:IPR011993 SMART:SM00233 PROSITE:PS50003 GO:GO:0046872 SUPFAM:SSF50044 GO:GO:0005089 Gene3D:1.20.900.10 SUPFAM:SSF48065 GO:GO:0005085 Gene3D:1.10.418.10 SUPFAM:SSF47576 GO:GO:0032319 InterPro:IPR011511 Pfam:PF07653 InterPro:IPR003096 PRINTS:PR00888 GO:GO:0048468 InterPro:IPR022613 Pfam:PF11971 GO:GO:0002768 HOVERGEN:HBG018066 PANTHER:PTHR22826:SF53 EMBL:U39476 UniGene:Rn.48861 ProteinModelPortal:P54100 SMR:P54100 PRIDE:P54100 Genevestigator:P54100 Uniprot:P54100) HSP 1 Score: 181.03 bits (458), Expect = 1.412e-46 Identity = 157/593 (26.48%), Postives = 264/593 (44.52%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDA--ETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGLNIKGSQVG-----EIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIH----------------------CLGKIDVVEKTIKLM---QLP---RGAQLSDFGRLRKAGELTAENSYGARLSD-YAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPLFHRIV-----PHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYP 574
M LW++C WL +V+PP H++ T +++ + +RDGVLLCQL+++L P ++++ V SQ F+C NI FL F L E FE DL+ Q+ G VI TLSALS + + FP ++ L +E+IYS + + D E E +YD + + + YE++ ++ P + + KR + E+ TE+KY + L ++ F L L +D E IF ++EL+ +HT L L S G ++F++ +YG YC + ++ + + ++ +L C +A F L L++P QR LK ++ ++V H C+ ++ +T++ + QL L+++GR + GEL + +D YAFL D +L+C R Y + +V + +++ S ++ H + L F R + W + A+ + P+ GH M +F+E TSC C ++ G F+QGYRC RC+A HK+C+G P
Sbjct: 1 MELWRQCTHWLIQCRVLPPSHRV--TWEGAQVCELAQALRDGVLLCQLLNNLLPHAINLREVNLRPQMSQ-------FLCLKNIRTFLSTCCEKFGLKRSE-LFEAFDLFDVQDFGKVIYTLSALSWTPIAQNKGIMPFPTEDSALG-----DEDIYSGLSDQIDDTAEEDEDLYDCVENE-EAEGDEIYEDLMRSESVPTPPKMT---------EYDKRCCCLREIQQTEEKYTDTLGSIQQHFMKPLQRFLKPQDMETIFVNIEELLSVHTHFLKELKDALSGPGATMLYQVFIKYKERFL-VYGRYCSQVESAIKHLDQVATAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQDTTEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLANYGRPKIDGELKITSVERRSKTDRYAFLLDKALLICKRRG---DSYDLKASVNLHSFQVRDDSSGERDNKKWSHMFLLIEDQGAQGYELFFKTRELKKK--WMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCYRCRAPAHKECLGRVP 562
BLAST of EMLSAG00000000123 vs. GO
Match: - (symbol:Vav1 "vav 1 oncogene" species:10090 "Mus musculus" [GO:0005085 "guanyl-nucleotide exchange factor activity" evidence=ISO] [GO:0005089 "Rho guanyl-nucleotide exchange factor activity" evidence=IGI] [GO:0005515 "protein binding" evidence=IPI] [GO:0005622 "intracellular" evidence=IMP] [GO:0005911 "cell-cell junction" evidence=IDA] [GO:0006909 "phagocytosis" evidence=IGI] [GO:0006955 "immune response" evidence=IMP] [GO:0007186 "G-protein coupled receptor signaling pathway" evidence=IGI] [GO:0007229 "integrin-mediated signaling pathway" evidence=IGI] [GO:0007264 "small GTPase mediated signal transduction" evidence=IEA] [GO:0030217 "T cell differentiation" evidence=IGI;TAS] [GO:0030593 "neutrophil chemotaxis" evidence=IGI] [GO:0030676 "Rac guanyl-nucleotide exchange factor activity" evidence=IGI] [GO:0032314 "regulation of Rac GTPase activity" evidence=IGI] [GO:0032855 "positive regulation of Rac GTPase activity" evidence=IGI] [GO:0035023 "regulation of Rho protein signal transduction" evidence=IEA] [GO:0035556 "intracellular signal transduction" evidence=IMP] [GO:0042110 "T cell activation" evidence=IMP] [GO:0043087 "regulation of GTPase activity" evidence=ISO;IGI] [GO:0045785 "positive regulation of cell adhesion" evidence=IGI] [GO:0046872 "metal ion binding" evidence=IEA] [GO:0072593 "reactive oxygen species metabolic process" evidence=IGI] Pfam:PF00018 Pfam:PF00017 Pfam:PF00169 InterPro:IPR000219 InterPro:IPR000980 InterPro:IPR001331 InterPro:IPR001452 InterPro:IPR001715 InterPro:IPR002219 InterPro:IPR028530 Pfam:PF00130 Pfam:PF00621 PRINTS:PR00401 PRINTS:PR00452 PROSITE:PS00479 PROSITE:PS00741 PROSITE:PS50001 PROSITE:PS50002 PROSITE:PS50010 PROSITE:PS50021 PROSITE:PS50081 SMART:SM00033 SMART:SM00109 SMART:SM00252 SMART:SM00325 SMART:SM00326 InterPro:IPR001849 MGI:MGI:98923 GO:GO:0005829 GO:GO:0007264 GO:GO:0006955 GO:GO:0006909 Gene3D:2.30.29.30 Gene3D:3.30.505.10 InterPro:IPR011993 SMART:SM00233 PROSITE:PS50003 GO:GO:0035556 GO:GO:0046872 SUPFAM:SSF50044 Gene3D:1.20.900.10 SUPFAM:SSF48065 Gene3D:1.10.418.10 SUPFAM:SSF47576 GO:GO:0007229 GO:GO:0045785 GO:GO:0030676 InterPro:IPR011511 Pfam:PF07653 InterPro:IPR003096 PRINTS:PR00888 InterPro:IPR022613 Pfam:PF11971 GO:GO:0030217 PDB:1GCQ PDBsum:1GCQ PDB:2VRW PDBsum:2VRW eggNOG:NOG326494 HOVERGEN:HBG018066 KO:K05730 TreeFam:TF316171 PANTHER:PTHR22826:SF53 HOGENOM:HOG000234364 CTD:7409 OMA:SHRVTWD EMBL:X64361 EMBL:AK088586 EMBL:M59833 PIR:A61187 RefSeq:NP_035821.3 UniGene:Mm.248172 PDB:1F5X PDB:1GCP PDB:1K1Z PDB:2KBT PDBsum:1F5X PDBsum:1GCP PDBsum:1K1Z PDBsum:2KBT ProteinModelPortal:P27870 SMR:P27870 BioGrid:204500 DIP:DIP-31010N IntAct:P27870 MINT:MINT-85069 PhosphoSite:P27870 PaxDb:P27870 PRIDE:P27870 Ensembl:ENSMUST00000005889 GeneID:22324 KEGG:mmu:22324 UCSC:uc008dep.2 InParanoid:P27870 EvolutionaryTrace:P27870 NextBio:302549 PRO:PR:P27870 ArrayExpress:P27870 Bgee:P27870 CleanEx:MM_VAV1 Genevestigator:P27870 Uniprot:P27870) HSP 1 Score: 179.489 bits (454), Expect = 4.540e-46 Identity = 157/593 (26.48%), Postives = 262/593 (44.18%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDA--ETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGLNIKGSQVG-----EIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIH----------------------CLGKIDVVEKTIKLM---QLP---RGAQLSDFGRLRKAGELTAENSYGARLSD-YAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPLFHRIV-----PHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYP 574
M LW++C WL +V+PP H++ T +++ + +RDGVLLCQL+++L P ++++ V SQ F+C NI FL F L E FE DL+ Q+ G VI TLSALS + + FP ++ L N+E+IYS + + D E E +YD + + + YE++ + P + + KR + E+ TE+KY + L ++ F L L +D E IF ++EL +HT L L + G ++F++ +YG YC + + + + ++ +L C +A F L L++P QR LK ++ ++V H C+ ++ +T++ + QL L+++GR + GEL + +D YAFL D +L+C R Y + +V + +++ S ++ H + L F R + W + A+ + P+ GH M +F+E TSC C ++ G F+QGYRC RC+A HK+C+G P
Sbjct: 1 MELWRQCTHWLIQCRVLPPSHRV--TWEGAQVCELAQALRDGVLLCQLLNNLLPQAINLREVNLRPQMSQ-------FLCLKNIRTFLSTCCEKFGLKRSE-LFEAFDLFDVQDFGKVIYTLSALSWTPIAQNKGIMPFPTEDSAL-----NDEDIYSGLSDQIDDTAEEDEDLYDCVENE-EAEGDEIYEDLMRLESVPTPPKMT---------EYDKRCCCLREIQQTEEKYTDTLGSIQQHFMKPLQRFLKPQDMETIFVNIEELFSVHTHFLKELKDALAGPGATTLYQVFIKYKERFL-VYGRYCSQVESASKHLDQVATAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQDATEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLANYGRPKIDGELKITSVERRSKTDRYAFLLDKALLICKRRG---DSYDLKASVNLHSFQVRDDSSGERDNKKWSHMFLLIEDQGAQGYELFFKTRELKKK--WMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCYRCRAPAHKECLGRVP 562
BLAST of EMLSAG00000000123 vs. GO
Match: - (symbol:vav3b "vav 3 guanine nucleotide exchange factor b" species:7955 "Danio rerio" [GO:0005085 "guanyl-nucleotide exchange factor activity" evidence=IEA] [GO:0035556 "intracellular signal transduction" evidence=IEA] [GO:0005089 "Rho guanyl-nucleotide exchange factor activity" evidence=IEA] [GO:0035023 "regulation of Rho protein signal transduction" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] Pfam:PF00017 Pfam:PF00169 InterPro:IPR000219 InterPro:IPR000980 InterPro:IPR001331 InterPro:IPR001452 InterPro:IPR001715 InterPro:IPR002219 InterPro:IPR028530 Pfam:PF00130 Pfam:PF00621 PRINTS:PR00452 PROSITE:PS00479 PROSITE:PS00741 PROSITE:PS50001 PROSITE:PS50002 PROSITE:PS50010 PROSITE:PS50021 PROSITE:PS50081 SMART:SM00033 SMART:SM00109 SMART:SM00252 SMART:SM00325 SMART:SM00326 InterPro:IPR001849 ZFIN:ZDB-GENE-070912-251 GO:GO:0007264 Gene3D:2.30.29.30 Gene3D:3.30.505.10 InterPro:IPR011993 SMART:SM00233 PROSITE:PS50003 GO:GO:0046872 SUPFAM:SSF50044 GO:GO:0005089 Gene3D:1.20.900.10 SUPFAM:SSF48065 Gene3D:1.10.418.10 SUPFAM:SSF47576 GO:GO:0032319 InterPro:IPR011511 Pfam:PF07653 InterPro:IPR003096 PRINTS:PR00888 InterPro:IPR022613 Pfam:PF11971 eggNOG:NOG326494 HOVERGEN:HBG018066 KO:K05730 OrthoDB:EOG73FQKZ TreeFam:TF316171 PANTHER:PTHR22826:SF53 GeneTree:ENSGT00740000115307 HOGENOM:HOG000234364 OMA:DPGLPKM EMBL:BX510321 EMBL:CR788310 EMBL:CT027695 RefSeq:NP_001119865.1 UniGene:Dr.10031 ProteinModelPortal:B0S6C8 SMR:B0S6C8 STRING:7955.ENSDARP00000102453 Ensembl:ENSDART00000110059 GeneID:559145 KEGG:dre:559145 CTD:559145 NextBio:20882815 ArrayExpress:B0S6C8 Uniprot:B0S6C8) HSP 1 Score: 176.792 bits (447), Expect = 2.551e-45 Identity = 143/589 (24.28%), Postives = 256/589 (43.46%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGL-----NIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIV--------------------------------IHCLGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARLSD-YAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHP--NSIPLFHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIG 571
M W++C WL N KV+P H++ T ++++ D +RDGVLLCQL+++L P ++++ + SQ F+C NI FL A F + + FE DL+ ++ G VI+TLS LS+ ++S + FP +E E+IY + ++ + E +YD DI + + YE++ +T A + + ++I R + E+ TE KY E L + F L + + D + +F + +L+++H ++ + N + +IF+ + LYG YC H+ ++ + + KE +R +L C +A F L L++P QR LK ++ ++V + L +ID +++I+ + L +GR + GE+ ++ R D + FLFD +++C R Y + + + ++I F+ F+ + ++ W A+ + P+ H M TF+ T+C C ++ GIF QGY C +C HK C+G
Sbjct: 1 MEYWRQCSLWLINCKVLPRNHRV--TADSAQVFDLAQTLRDGVLLCQLLNNLRPDTINLKEINLRPQMSQ-------FLCLKNIRTFLSACCEEFGMKKSD-LFEAFDLFDVRDFGKVIDTLSKLSYTPVAQQSGIRSFPTEES------TENEDIYIHLADLIDEELEEDVYDPVYGDI--EGGEVYEDLMRTEAAKQAE---VDI----------RSCCLLEIKQTEAKYTETLETIEKYFMIPLMKFIPATDIDKVFINIPDLVKVHKGLMGEIQDCVQNKNAENLHQIFITYKDRLL-LYGKYCSHVESAISLLDFICKEKEGVRLKLEECSKRANNGKFTLRDLLVVPMQRVLKYPLLLQELVKYTNDGPEKSNLRIALDAMRDLAQYVNEVKRDVETLREIDQYQRSIENLN----QSLLSYGRPKGDGEVRLVSNLDKRRQDRHIFLFDAAVIICKRRG---DNYEMKEVIDLSHFKITNNLADKDCRKWSSGFYLTHQQGQSGFEFLFKTKELKKKWLDQFEMAISNIRPENATFNSHHFRMHTFERATTCSSCRMLLRGIFNQGYLCPKCGNGAHKGCLG 550
BLAST of EMLSAG00000000123 vs. C. finmarchicus
Match: gi|592819420|gb|GAXK01135148.1| (TSA: Calanus finmarchicus comp240255_c1_seq3 transcribed RNA sequence) HSP 1 Score: 185.652 bits (470), Expect = 4.201e-53 Identity = 100/173 (57.80%), Postives = 126/173 (72.83%), Query Frame = 0
Query: 26 LWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGD--AETEYIY 196
LWKEC+AWL FKVIP GH +L T + D V L+RDGV+LCQLVH LDPSSVDMT+V+Y++PE++ + SDF+CR+NIFLFL+A V+NF L+TD+HFFEP LY ++I V+ TLSALSH K S + GFPKKEK L KKI+NEE IY S++ Y + E IY
Sbjct: 26 LWKECLAWLDKFKVIPRGHPVLAT--GAGPHDLVLLLRDGVILCQLVHCLDPSSVDMTQVVYASPEAE---AVSDFVCRNNIFLFLYAAVNNFQLDTDDHFFEPTALYQYKDISKVLRTLSALSHSTKFLASQISGFPKKEKKLEKKIQNEEQIYDSLRNYYNTVLSNNESIY 529
BLAST of EMLSAG00000000123 vs. C. finmarchicus
Match: gi|592819422|gb|GAXK01135146.1| (TSA: Calanus finmarchicus comp240255_c1_seq1 transcribed RNA sequence) HSP 1 Score: 179.874 bits (455), Expect = 6.771e-50 Identity = 100/284 (35.21%), Postives = 154/284 (54.23%), Query Frame = 0
Query: 339 EKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHC--------------------------------------------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQT-SPSHPNSIPLFHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLE 577
E+ +PKL+ +L CQ KA+ + FPL +H++LPFQR LK M+ +I+ H L ++ VE+TIK M LP GA+L DFGRLR+AG+L + G + +DY FL DTI+++C +P +Q RYRF++A+K+++YR+ +T + N+I LFHR+ P ++ + +++ + ++W KA+ ++D + P EN H L MT C C + G+ QGYRC+ C A+LHK CI D C E
Sbjct: 33 EQRNPKLKKELNKCQIKAK-SPFPLCAHIVLPFQRLLKYHIMLAEILKHTPETHEEYLDLELAHNHMKNFNSEVNEAKREQEDNEKQMIQDEKDLAILENVERTIKSMHLPNGAKLKDFGRLRRAGDLKVLSVSGDQ-TDYVFLLDTIMVMCNKPSIMQQRYRFKSALKLKEYRVEETRGGTAQNTIRLFHRMNLLSQP-IILLAKSSIELDLWLKALLTSMDFLYPSENKGSRHDLIMTNLP-ALECTACKKKFLGMIAQGYRCRGCHAILHKSCIPDLMCRE 872
BLAST of EMLSAG00000000123 vs. C. finmarchicus
Match: gi|592819430|gb|GAXK01135138.1| (TSA: Calanus finmarchicus comp240255_c0_seq2 transcribed RNA sequence) HSP 1 Score: 147.902 bits (372), Expect = 1.372e-39 Identity = 72/180 (40.00%), Postives = 114/180 (63.33%), Query Frame = 0
Query: 389 LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQT-SPSHPNSIPLFHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHK 567
L ++ VE+TIK M LP GA+L DFGRLR+AG+L + G + +DY FL DTI+++C +P +Q RYRF++A+K+++YR+ +T + N+I LFHR+ P ++ + +++ + ++W KA+ ++D + P EN H L MT C C + G+ QGYRC+ C A+LHK
Sbjct: 73 LAILENVERTIKSMHLPNGAKLKDFGRLRRAGDLKVLSVSGDQ-TDYVFLLDTIMVMCNKPSIMQQRYRFKSALKLKEYRVEETRGGTAQNTIRLFHRMNLLSQP-IILLAKSSIELDLWLKALLTSMDFLYPSENKGSRHDLIMTNL-PALECTACKKKFLGMIAQGYRCRGCHAILHK 603
BLAST of EMLSAG00000000123 vs. C. finmarchicus
Match: gi|592819421|gb|GAXK01135147.1| (TSA: Calanus finmarchicus comp240255_c1_seq2 transcribed RNA sequence) HSP 1 Score: 139.813 bits (351), Expect = 1.422e-36 Identity = 95/209 (45.45%), Postives = 125/209 (59.81%), Query Frame = 0
Query: 129 PEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGD--AETEYIYDSFAKDIYN-----DTQDN-YENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQL-TLLSSKDKELIFYKLDELIRLHTEILTGLNIKGSQVGEIFLRLNPIIARLYGDYCVHL 328
P LY ++I V+ TLSALSH K S + GFPKKEK L KKI+NEE IY S++ Y + E IY D + + DN Y++IYQTIC+P+ R SL+I S KSKR+ PI E +TEDKYL NLIMVRD F Q+ LL E+IF++L ELI LH++IL L + S +G++ L+ +Y DYC +L
Sbjct: 3 PTALYQYKDISKVLRTLSALSHSTKFLASQISGFPKKEKKLEKKIQNEEQIYDSLRNYYNTVLSNNESIYSPQKVDPKSPIKEAEIPDNIYDDIYQTICSPRKSRMSLDI---SFSKKSKREYPIKEFSETEDKYLANLIMVRDNFLSQMQNLLQPNMVEIIFFRLHELITLHSDILLDLKKRKSNIGQVILKYRQDF-EVYKDYCTNL 617
BLAST of EMLSAG00000000123 vs. C. finmarchicus
Match: gi|592819431|gb|GAXK01135137.1| (TSA: Calanus finmarchicus comp240255_c0_seq1 transcribed RNA sequence) HSP 1 Score: 107.842 bits (268), Expect = 2.543e-25 Identity = 66/196 (33.67%), Postives = 98/196 (50.00%), Query Frame = 0
Query: 271 TLLSSKDKELIFYKLDELIRLHTEILTGLNIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHC--------------------------------------------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGEL 422
LL E+IF++L ELI LH++IL L + S +G++ L+ +Y DYC +L + + E+ +PKL+ +L CQ KA+ + FPL +H++LPFQR LK M+ +I+ H L ++ VE+TIK M LP GA+L DFGRLR+AG+L
Sbjct: 23 NLLQPNMVEIIFFRLHELITLHSDILLDLKKRKSNIGQVILKYRQDF-EVYKDYCTNLSHAQAVLEAEEQRNPKLKKELNKCQIKAK-SPFPLCAHIVLPFQRLLKYHIMLAEILKHTPETHEEYLDLELAHNHMKNFNSEVNEAKREQEDNEKQMIQDEKDLAILENVERTIKSMHLPNGAKLKDFGRLRRAGDL 604
BLAST of EMLSAG00000000123 vs. C. finmarchicus
Match: gi|592819418|gb|GAXK01135150.1| (TSA: Calanus finmarchicus comp240255_c1_seq5 transcribed RNA sequence) HSP 1 Score: 104.76 bits (260), Expect = 8.090e-25 Identity = 72/150 (48.00%), Postives = 91/150 (60.67%), Query Frame = 0
Query: 129 PEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGD--AETEYIYDSFAKDIYN-----DTQDN-YENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQL 270
P LY ++I V+ TLSALSH K S + GFPKKEK L KKI+NEE IY S++ Y + E IY D + + DN Y++IYQTIC+P+ R SL+I S KSKR+ PI E +TEDKYL NLIMVR+ F Q+
Sbjct: 2 PTALYQYKDISKVLRTLSALSHSTKFLASQISGFPKKEKKLEKKIQNEEQIYDSLRNYYNTVLSNNESIYSPQKVDPKSPIKEAEIPDNIYDDIYQTICSPRKSRMSLDI---SFSKKSKREYPIKEFSETEDKYLANLIMVRENFLSQM 442
BLAST of EMLSAG00000000123 vs. C. finmarchicus
Match: gi|592819426|gb|GAXK01135142.1| (TSA: Calanus finmarchicus comp240255_c0_seq6 transcribed RNA sequence) HSP 1 Score: 71.633 bits (174), Expect = 1.825e-13 Identity = 44/128 (34.38%), Postives = 62/128 (48.44%), Query Frame = 0
Query: 339 EKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHC--------------------------------------------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGEL 422
E+ +PKL+ +L CQ KA+ + FPL +H++LPFQR LK M+ +I+ H L ++ VE+TIK M LP GA+L DFGRLR+AG+L
Sbjct: 10 EQRNPKLKKELNKCQIKAK-SPFPLCAHIVLPFQRLLKYHIMLAEILKHTPETHEEYLDLELAHNHMKNFNSEVNEAKREQEDNEKQMIQDEKDLAILENVERTIKSMHLPNGAKLKDFGRLRRAGDL 390
BLAST of EMLSAG00000000123 vs. C. finmarchicus
Match: gi|592819427|gb|GAXK01135141.1| (TSA: Calanus finmarchicus comp240255_c0_seq5 transcribed RNA sequence) HSP 1 Score: 71.633 bits (174), Expect = 1.971e-13 Identity = 44/128 (34.38%), Postives = 62/128 (48.44%), Query Frame = 0
Query: 339 EKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHC--------------------------------------------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGEL 422
E+ +PKL+ +L CQ KA+ + FPL +H++LPFQR LK M+ +I+ H L ++ VE+TIK M LP GA+L DFGRLR+AG+L
Sbjct: 22 EQRNPKLKKELNKCQIKAK-SPFPLCAHIVLPFQRLLKYHIMLAEILKHTPETHEEYLDLELAHNHMKNFNSEVNEAKREQEDNEKQMIQDEKDLAILENVERTIKSMHLPNGAKLKDFGRLRRAGDL 402
BLAST of EMLSAG00000000123 vs. C. finmarchicus
Match: gi|592920823|gb|GAXK01037552.1| (TSA: Calanus finmarchicus comp362769_c0_seq2 transcribed RNA sequence) HSP 1 Score: 66.2402 bits (160), Expect = 1.018e-11 Identity = 38/132 (28.79%), Postives = 67/132 (50.76%), Query Frame = 0
Query: 438 LFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIG-------QTSPSHPNSIPLFHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQ 562
+FD ++L+C + + Y F+ +K++DY++ T S L H+ H + LF R ++ W +AI +A + P + H M TF + +SC C++++ G+F+QGY CQ+CQ
Sbjct: 1 VFDKMLLICKQTR--GDHYSFKEGLKVQDYKVQDVSLRRLSTDARWAYSFMLVHKENLHA--YTLFA-RTEEEKNKWIEAIKEAQNNEVPSQRFNSTHDPLMHTFDKPSSCQYCHKLLKGLFYQGYLCQKCQ 381
BLAST of EMLSAG00000000123 vs. C. finmarchicus
Match: gi|592819423|gb|GAXK01135145.1| (TSA: Calanus finmarchicus comp240255_c0_seq9 transcribed RNA sequence) HSP 1 Score: 65.855 bits (159), Expect = 1.117e-11 Identity = 38/68 (55.88%), Postives = 47/68 (69.12%), Query Frame = 0
Query: 121 NTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYG 188
+TD+HFFEP LY ++I V+ TLSALSH K S + GFPKKEK L KKI+NEE IY S++ Y
Sbjct: 2 DTDDHFFEPTALYQYKDISKVLRTLSALSHSTKFLASQISGFPKKEKKLEKKIQNEEQIYDSLRNYYN 205
BLAST of EMLSAG00000000123 vs. L. salmonis peptides
Match: EMLSAP00000000123 (pep:novel supercontig:LSalAtl2s:LSalAtl2s101:528275:535129:-1 gene:EMLSAG00000000123 transcript:EMLSAT00000000123 description:"snap_masked-LSalAtl2s101-processed-gene-5.13") HSP 1 Score: 1410.59 bits (3650), Expect = 0.000e+0 Identity = 679/679 (100.00%), Postives = 679/679 (100.00%), Query Frame = 0
Query: 1 MDRFCEINPDDRLRIGGNTQSFNMVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTLLSSKDKELIFYKLDELIRLHTEILTGLNIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHCLGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPLFHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGSTNSNASSINNNGLTKCDSVTLPTVINEPLERSESTLSLSPDSKQPSADRVSKLQRETEEELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVRKRK 679
MDRFCEINPDDRLRIGGNTQSFNMVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTLLSSKDKELIFYKLDELIRLHTEILTGLNIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHCLGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPLFHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGSTNSNASSINNNGLTKCDSVTLPTVINEPLERSESTLSLSPDSKQPSADRVSKLQRETEEELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVRKRK
Sbjct: 1 MDRFCEINPDDRLRIGGNTQSFNMVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTLLSSKDKELIFYKLDELIRLHTEILTGLNIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHCLGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPLFHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGSTNSNASSINNNGLTKCDSVTLPTVINEPLERSESTLSLSPDSKQPSADRVSKLQRETEEELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVRKRK 679
BLAST of EMLSAG00000000123 vs. L. salmonis peptides
Match: EMLSAP00000003826 (pep:novel supercontig:LSalAtl2s:LSalAtl2s2071:1578:3887:1 gene:EMLSAG00000003826 transcript:EMLSAT00000003826 description:"maker-LSalAtl2s2071-snap-gene-0.3") HSP 1 Score: 114.005 bits (284), Expect = 2.471e-27 Identity = 93/345 (26.96%), Postives = 160/345 (46.38%), Query Frame = 0
Query: 176 EENIYSSMKEIYGDAETEYIY-----DSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTLLSSKDKELIFYKLDELIRLHTEILTGL--NIKG---SQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNS------------------------EMIIDIVIHC---------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGEL---TAENSYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSP 474
EE IY ++++I + + + Y + Y+ D E IYQ +C+ ++ + E+ +++ K KRD I E+I+TE Y++ L M+R F +T + DK++IF + EL H L I+G ++GE+FL + YG+YC LP+S D + + K D +R + + + F L L +P QR LK E ++D+ + L I +E +I +P G +L D+GRLRK GEL + ++ G + F+FD ++L+C +P H Y ++ ++K+ DY++ P
Sbjct: 42 EEQIYRTLEDIINEDKYQEFYFKHHGAAGKSHYYSGEDDKEEGIYQDLCSLQSLKIRAEL---NIQPKEKRDYCIKEIIETESNYVDVLNMLRKNFIKTITKMRDTDKKIIFMNIIELGDTHAGFYQNLCDVIRGKSCKKIGEVFLEYKTRFLK-YGEYCSCLPKSQDVLDNVMK-DEXVREXIALYEKSVKDGKFRLRDLLAVPMQRILKYHLLLKGLLDTTKPTHEEYRIIQQAYESMLDVSDYINEVKRDSEQLHIIKEIEASINDWNMPDGYELKDYGRLRKDGELKVHSHDSHAGKTKLRFVFIFDKVMLMC-KPARGDH-YSYKDSLKLADYKVQDERP 379
BLAST of EMLSAG00000000123 vs. L. salmonis peptides
Match: EMLSAP00000009074 (pep:novel supercontig:LSalAtl2s:LSalAtl2s56:477026:514584:1 gene:EMLSAG00000009074 transcript:EMLSAT00000009074 description:"maker-LSalAtl2s56-snap-gene-5.8") HSP 1 Score: 63.5438 bits (153), Expect = 1.140e-10 Identity = 67/255 (26.27%), Postives = 116/255 (45.49%), Query Frame = 0
Query: 238 KSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTLLSSKDKELIFYKLDELIRLHTEI----LTGLNIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKE-DPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIV----IHC------------LGKIDVVEKT---IKLMQLPRGAQLSDFGRL--RKAGELTAENSYGARL-------SDYAFLFDTIILLCTRPKWLQHRYRFR 459
K++R+ I+EL+ TE +Y+ +L V +RD+L + ++K +IF LDE+ H+ I L + + + F + LY YC ++P + + L E P + L+ CQ +A PL+S+L+ P QR K M+ D+V + C L I VV + + + LP+ +S G L ++T+EN +++ + FL+D IL+C Y+F+
Sbjct: 339 KTRRENIISELLSTESRYVSDLESVLLNYRDKLVIANNK-ANIIFGNLDEIHDFHSNILYPDLERCGVXPAAIARTFSACCQDLKTLYCAYCQNMPSARQAVAELGGEATPSI---LYQCQTEA-GHQLPLSSYLLKPMQRLTKYQLMLRDLVESSNVVCGKEDLDDALSSLLNVIKVVNDSLNEVNIKGLPKA--VSPLGSLVAHDVFQVTSENKSQSQILFRNRSQRRHVFLYDNHILICKPVNEKTQNYQFK 586
BLAST of EMLSAG00000000123 vs. SwissProt
Match: gi|21759460|sp|Q9NHV9.2|VAV_DROME (RecName: Full=Protein vav; Short=DroVav; Short=dVAV) HSP 1 Score: 213.772 bits (543), Expect = 2.766e-58 Identity = 202/722 (27.98%), Postives = 319/722 (44.18%), Query Frame = 0
Query: 17 GNTQSFNMVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKR--SSVPGF-----PKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTLLSSKDK-ELIFYKLDELIRLHTEILTGL------NIKGSQVGEIFLRL-NPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK------------------------NSEMIIDI------VIHCLGKIDVVEKT------IKLMQLPRGAQLSDFGRLRKAGEL--TAENSYGARLSDYAFLFDTIILL--CTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHP---NSIPLFHRIVPHPTPHLLFV--CRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGSTNSNASSINNNGLTKCDSVTLPTVINEPLERSESTLSLSPDSKQPSADRVSKLQRETEEELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVRKR 678
G N LW+ECVAWL KVIPP HK Q ++++ +RDGVLLC LV LDPSS+D R P+ + F+C NI LFL +NF + D FEP LY N V+ TLS LS C KV++ + GF P + H ++E IY K+++ + Y+ T E +YQ +CA R S SS S +RD I ELIDTE YL+ L ++ F L ++D+ LIF ++ EL+ +HT+ L L N K ++ ++FL P + +YG++C L ++D++ + K++ + + C+ L L +P QR LK E +ID+ V + +++K I L+Q G+ L +GRL GEL A +L YAF+FD I+++ K +Y +R + + DYR+ Q+ ++ + ++ + F ++ +R+ WRKA+T+A++ +EP H + + TF T+C C++ + G QGYRC+ CQ +HK C I++ G K + V++P P DR + +WFAG+++ +TA+ RL++ +GT+L+R R
Sbjct: 11 GGVAGVNGDLWRECVAWLTRCKVIPPDHKAAQP--DAEIRILAMTLRDGVLLCNLVIHLDPSSLD-PREFNRKPQ------MAQFLCSKNIKLFLDVCHNNFGIR-DADLFEPTMLYDLTNFHRVLITLSKLSQCRKVQQLHPDLIGFNLQLSPTERSH------SDEAIY---KDLHSTTTDNIACNGTG---YDHTNTKEEEVYQDLCA--LHRTSRSQTASS-TSFEQRDYVIRELIDTESNYLDVLTALKTKFMGPLERHLNQDELRLIFPRIRELVDIHTKFLDKLRESLTPNAK-VKMAQVFLDFREPFL--IYGEFCSLLLGAIDYLADVCKKNQIIDQLVQKCERDYNVGKLQLRDILSVPMQRILKYHLLLDKLVKETSPLHDDYRSLERAKEAMIDVSQYINEVKRDSDHLVIIQKVKDSICDIHLLQNGNGSDLLQYGRLLLDGELHIKAHEDQKTKLR-YAFVFDKILIMVKALHIKTGDMQYTYRDSHNLADYRVEQSHSRRTIGRDTRFKYQLLLARKSGKTAFTLYLKSEHERDKWRKALTEAMESLEPPGCQSTDHKMEIYTFDAPTTCRHCSKFLKGRIHQGYRCKVCQISVHKGC------------------ISSTGRCKQNPVSVPP---------------------PVCDR---------------QLSEFNWFAGNMDRETAAHRLENRRIGTYLLRVR 649
BLAST of EMLSAG00000000123 vs. SwissProt
Match: gi|2494862|sp|Q60992.1|VAV2_MOUSE (RecName: Full=Guanine nucleotide exchange factor VAV2; Short=VAV-2) HSP 1 Score: 200.29 bits (508), Expect = 2.711e-53 Identity = 152/601 (25.29%), Postives = 268/601 (44.59%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYN--DTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTL-LSSKDKELIFYKLDELIRLHTEILTGLNIK----GSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHC--------------------------------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARLSD-YAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPL----FHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGS 580
M W++C WL + KV+PP H+++ ++ + D +RDGVLLCQL+H+L P S+D+ + + SQ F+C NI FL F L E F+P DL+ ++ G VI +S LS + + + FP +E +N++++Y S++E+ + + +DIY+ +D ++IY+ I + Q + + KR + E+ +TE KY L + + L L LS D +F L++LI++H L +++ GS + ++FL + +YG+YC H+ + + L R ++ C + + F L L++P QR LK ++ +++ H L KI + +I+ +Q+ +L +FGR + GEL + D Y FLFD ++++C R + Y + +++ +++ P H I F+ I F C+ + W + A+ ++P + H M TF + T+C C + G F+QGY C RC HK+C+ P ++ S
Sbjct: 1 MEQWRQCGRWLIDCKVLPPNHRVVWP--SAVVFDLAQALRDGVLLCQLLHNLSPGSIDLKDINFRPQMSQ-------FLCLKNIRTFLKVCHDKFGLRNSE-LFDPFDLFDVRDFGKVISAVSRLSLHSIAQSKGIRPFPSEET-----AENDDDVYRSLEELADEHD-------LGEDIYDCVPCEDEGDDIYEDIIKVEVQ----QPMKMGMTEDDKRSCCLLEIQETEAKYYRTLEDIEKNYMGPLRLVLSPADMAAVFINLEDLIKVHHSFLRAIDVSMMAGGSTLAKVFLEFKERLL-IYGEYCSHMEHAQSTLNQLLASREDFRQKVEECTLRVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSADRPERQQLKEALEAMQDLAMYINEVKRDKETLKKISEFQCSIENLQV----KLEEFGRPKIDGELKVRSIVNHTKQDRYLFLFDKVVIVCKRKG---YSYELKEVIELLFHKM-TDDPMHNKDIKKWSYGFYLIHLQGKQGFQFFCKTEDMKRKWMEQFEMAMSNIKPDKANANHHSFQMYTFDKTTNCKACKMFLRGTFYQGYLCTRCGVGAHKECLEVIPPCKMSS 566
BLAST of EMLSAG00000000123 vs. SwissProt
Match: gi|212287930|sp|P52735.2|VAV2_HUMAN (RecName: Full=Guanine nucleotide exchange factor VAV2; Short=VAV-2) HSP 1 Score: 199.904 bits (507), Expect = 4.923e-53 Identity = 177/733 (24.15%), Postives = 310/733 (42.29%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYN--DTQDNYENIYQTICAPKTQRFSLEIFGS-SLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTL-LSSKDKELIFYKLDELIRLHTEILTGLNIK----GSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHC--------------------------------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARLSD-YAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRI-------GQTSPSHPNSIPL-FHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDY-PCLEVGSTNSNASSI----------NNNG---------LTKCDSVTLPTVINEP---------LERSESTLSLSPDSKQPSADRVSKLQRETEEELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVRKR 678
M W++C WL + KV+PP H+++ ++ + D +RDGVLLCQL+H+L P S+D+ + + SQ F+C NI FL F L E F+P DL+ ++ G VI +S LS + + + FP +E +N++++Y S++E+ + + +DIY+ +D ++IY+ I + Q+ + + KR+ + E+ +TE KY L + + L L LS D +F L++LI++H L +++ GS + ++FL + +YG+YC H+ + + + L R ++ C K + F L L++P QR LK ++ +++ H L KI + +I+ +Q+ +L +FGR + GEL + D Y FLFD ++++C R + Y + +++ +++ SH F+ I F C+ + W + A+ ++P + H M TF + T+C C + G F+QGY C +C HK+C+ PC + +AS N +G LT L + +P ++ +S S K D + R E I WFAG++ + L+S GT+L+R+R
Sbjct: 1 MEQWRQCGRWLIDCKVLPPNHRVVWP--SAVVFDLAQALRDGVLLCQLLHNLSPGSIDLKDINFRPQMSQ-------FLCLKNIRTFLKVCHDKFGLRNSE-LFDPFDLFDVRDFGKVISAVSRLSLHSIAQNKGIRPFPSEET-----TENDDDVYRSLEELADEHD-------LGEDIYDCVPCEDGGDDIYEDIIKVEVQQPMIRYMQKMGMTEDDKRNCCLLEIQETEAKYYRTLEDIEKNYMSPLRLVLSPADMAAVFINLEDLIKVHHSFLRAIDVSVMVGGSTLAKVFLDFKERLL-IYGEYCSHMEHAQNTLNQLLASREDFRQKVEECTLKVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSAERPERQQLKEALEAMQDLAMYINEVKRDKETLRKISEFQSSIENLQV----KLEEFGRPKIDGELKVRSIVNHTKQDRYLFLFDKVVIVCKRKG---YSYELKEIIELLFHKMTDDPMNNKDVKKSHGKMWSYGFYLIHLQGKQGFQFFCKTEDMKRKWMEQFEMAMSNIKPDKANANHHSFQMYTFDKTTNCKACKMFLRGTFYQGYMCTKCGVGAHKECLEVIPPCKFTSPADLDASGAGPGPKMVAMQNYHGNPAPPGKPVLTFQTGDVLELLRGDPESPWWEGRLVQTRKSGYFPSSSVKPCPVDGRPPISRPPSRE---IDYTAYPWFAGNMERQQTDNLLKSHASGTYLIRER 700
BLAST of EMLSAG00000000123 vs. SwissProt
Match: gi|122132317|sp|Q08DN7.1|VAV_BOVIN (RecName: Full=Proto-oncogene vav) HSP 1 Score: 181.415 bits (459), Expect = 6.711e-47 Identity = 183/729 (25.10%), Postives = 306/729 (41.98%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDA--ETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGL-----NIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIH----------------------CLGKIDVVEKTIKLM---QLP---RGAQLSDFGRLRKAGELTAEN-SYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPLFHRIV-----PHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDY-PCLEVGSTNSNA------------SSINNNGLTKCDSVTLPTVINEPLERSESTLSLSP----------------DSKQPSADRVSKLQRETEEELINIPVERQS---WFAGDLNPKTASVRLQSLPVGTFLVRKR 678
M LW++C WL +V+PP H++ T +++ + +RDGVLLCQL+++L P ++++ V SQ F+C NI FL F L E FE DL+ Q+ G VI TLSALS + + FP +E +E+IYS + + D E E +YD + + + YE++ ++ P + + KR + E+ TE+KY + L ++ F L L +D E+IF +++L+R+HT L + N S + ++F++ +YG YC + + + + ++ +L C +A F L L++P QR LK ++ ++V H C+ ++ +T++ + QL L+ +GR + GEL + +++ YAFL D +L+C R Y + V + +++ S ++ H + L F R + W + A+ + P+ GH M +F+E TSC C ++ G F+QGYRCQRC+A HK+C+G PC G S N GL K + + P L L+P + + S + V + ++ P + S W+AG + A L + GTFLVR+R
Sbjct: 1 MELWRQCTHWLIQCRVLPPSHRV--TWDGAQVCELAQALRDGVLLCQLLNNLLPHAINLREVNLRPQMSQ-------FLCLKNIRTFLSTCYEKFGLKRSE-LFEAFDLFDVQDFGKVIYTLSALSWTPIAQNKGIMPFPTEES------VGDEDIYSGLSDQIDDTVEEDEDLYDCVENE-EAEGDEVYEDLMRSEPVPMPPKMT---------EYDKRCCCLREIQQTEEKYTDTLGSIQQHFMKPLQRFLKPQDVEIIFINIEDLLRVHTHFLKEMKEALANPGASTLYQVFIKYKERFL-IYGRYCSQVESASKHLDRVATAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQDAMEKDNLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLAHYGRPKIDGELKITSVERRSKMDRYAFLLDKALLICKRRG---DTYDLKDFVNLHSFQVRDDSSGERDNKKWTHMFLLIEDQGAQGYELFFKTRELKKK--WMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCQRCRAPAHKECLGRVPPCGRHGQDYSGTMKKDKPHRRAQDKKRNELGLPKMEVCQEYYGLPPPPGAIGPFLRLNPGDIVELTKAEAEQNWWEGRNISTNEVGWFPCNRVKPYVHGPPQDLSVHLWYAGPMERAGAESILTNRSDGTFLVRQR 697
BLAST of EMLSAG00000000123 vs. SwissProt
Match: gi|1718102|sp|P54100.1|VAV_RAT (RecName: Full=Proto-oncogene vav; AltName: Full=p95) HSP 1 Score: 181.03 bits (458), Expect = 1.139e-46 Identity = 157/593 (26.48%), Postives = 264/593 (44.52%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDA--ETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGLNIKGSQVG-----EIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIH----------------------CLGKIDVVEKTIKLM---QLP---RGAQLSDFGRLRKAGELTAENSYGARLSD-YAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPLFHRIV-----PHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYP 574
M LW++C WL +V+PP H++ T +++ + +RDGVLLCQL+++L P ++++ V SQ F+C NI FL F L E FE DL+ Q+ G VI TLSALS + + FP ++ L +E+IYS + + D E E +YD + + + YE++ ++ P + + KR + E+ TE+KY + L ++ F L L +D E IF ++EL+ +HT L L S G ++F++ +YG YC + ++ + + ++ +L C +A F L L++P QR LK ++ ++V H C+ ++ +T++ + QL L+++GR + GEL + +D YAFL D +L+C R Y + +V + +++ S ++ H + L F R + W + A+ + P+ GH M +F+E TSC C ++ G F+QGYRC RC+A HK+C+G P
Sbjct: 1 MELWRQCTHWLIQCRVLPPSHRV--TWEGAQVCELAQALRDGVLLCQLLNNLLPHAINLREVNLRPQMSQ-------FLCLKNIRTFLSTCCEKFGLKRSE-LFEAFDLFDVQDFGKVIYTLSALSWTPIAQNKGIMPFPTEDSALG-----DEDIYSGLSDQIDDTAEEDEDLYDCVENE-EAEGDEIYEDLMRSESVPTPPKMT---------EYDKRCCCLREIQQTEEKYTDTLGSIQQHFMKPLQRFLKPQDMETIFVNIEELLSVHTHFLKELKDALSGPGATMLYQVFIKYKERFL-VYGRYCSQVESAIKHLDQVATAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQDTTEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLANYGRPKIDGELKITSVERRSKTDRYAFLLDKALLICKRRG---DSYDLKASVNLHSFQVRDDSSGERDNKKWSHMFLLIEDQGAQGYELFFKTRELKKK--WMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCYRCRAPAHKECLGRVP 562
BLAST of EMLSAG00000000123 vs. SwissProt
Match: gi|137483|sp|P27870.1|VAV_MOUSE (RecName: Full=Proto-oncogene vav; AltName: Full=p95vav) HSP 1 Score: 179.489 bits (454), Expect = 3.644e-46 Identity = 157/593 (26.48%), Postives = 262/593 (44.18%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDA--ETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGLNIKGSQVG-----EIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIH----------------------CLGKIDVVEKTIKLM---QLP---RGAQLSDFGRLRKAGELTAENSYGARLSD-YAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPLFHRIV-----PHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYP 574
M LW++C WL +V+PP H++ T +++ + +RDGVLLCQL+++L P ++++ V SQ F+C NI FL F L E FE DL+ Q+ G VI TLSALS + + FP ++ L N+E+IYS + + D E E +YD + + + YE++ + P + + KR + E+ TE+KY + L ++ F L L +D E IF ++EL +HT L L + G ++F++ +YG YC + + + + ++ +L C +A F L L++P QR LK ++ ++V H C+ ++ +T++ + QL L+++GR + GEL + +D YAFL D +L+C R Y + +V + +++ S ++ H + L F R + W + A+ + P+ GH M +F+E TSC C ++ G F+QGYRC RC+A HK+C+G P
Sbjct: 1 MELWRQCTHWLIQCRVLPPSHRV--TWEGAQVCELAQALRDGVLLCQLLNNLLPQAINLREVNLRPQMSQ-------FLCLKNIRTFLSTCCEKFGLKRSE-LFEAFDLFDVQDFGKVIYTLSALSWTPIAQNKGIMPFPTEDSAL-----NDEDIYSGLSDQIDDTAEEDEDLYDCVENE-EAEGDEIYEDLMRLESVPTPPKMT---------EYDKRCCCLREIQQTEEKYTDTLGSIQQHFMKPLQRFLKPQDMETIFVNIEELFSVHTHFLKELKDALAGPGATTLYQVFIKYKERFL-VYGRYCSQVESASKHLDQVATAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQDATEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLANYGRPKIDGELKITSVERRSKTDRYAFLLDKALLICKRRG---DSYDLKASVNLHSFQVRDDSSGERDNKKWSHMFLLIEDQGAQGYELFFKTRELKKK--WMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCYRCRAPAHKECLGRVP 562
BLAST of EMLSAG00000000123 vs. SwissProt
Match: gi|13124807|sp|P15498.4|VAV_HUMAN (RecName: Full=Proto-oncogene vav) HSP 1 Score: 176.407 bits (446), Expect = 4.205e-45 Identity = 183/729 (25.10%), Postives = 310/729 (42.52%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDA--ETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHT----EILTGLNIKGS-QVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIH----------------------CLGKIDVVEKTIKLM---QLP---RGAQLSDFGRLRKAGELTAEN-SYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPLFHRIV-----PHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDY-PCLEVGST------------NSNASSINNNGLTKCDSVTLPTVINEPLERSESTLSLSPD-----SKQPSADRVSKLQRETEEELINIPVER--------------QSWFAGDLNPKTASVRLQSLPVGTFLVRKR 678
M LW++C WL +V+PP H++ T +++ + +RDGVLLCQL+++L P ++++ V SQ F+C NI FL F L E FE DL+ Q+ G VI TLSALS + + FP +E+ + +E+IYS + + D E E +YD + N+ + E IY+ + +++ S+ + KR + E+ TE+KY + L ++ F L L +D E+IF +++L+R+HT E+ L G+ + ++F++ +YG YC + + + + ++ +L C +A F L L++P QR LK ++ ++V H C+ ++ +T++ + QL L+ +GR + GEL + +++ YAFL D +L+C R Y + V + +++ S ++ H + L F R + W + A+ + P+ GH M +F+E TSC C ++ G F+QGYRC RC+A HK+C+G PC G + N GL K + + P L L+P +K + + + + E+ P R W+AG + A L + GTFLVR+R
Sbjct: 1 MELWRQCTHWLIQCRVLPPSHRV--TWDGAQVCELAQALRDGVLLCQLLNNLLPHAINLREVNLRPQMSQ-------FLCLKNIRTFLSTCCEKFGLKRSE-LFEAFDLFDVQDFGKVIYTLSALSWTPIAQNRGIMPFPTEEESVG-----DEDIYSGLSDQIDDTVEEDEDLYDC----VENEEAEGDE-IYEDLM--RSEPVSMP---PKMTEYDKRCCCLREIQQTEEKYTDTLGSIQQHFLKPLQRFLKPQDIEIIFINIEDLLRVHTHFLKEMKEALGTPGAANLYQVFIKYKERFL-VYGRYCSQVESASKHLDRVAAAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQEAMEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLAHYGRPKIDGELKITSVERRSKMDRYAFLLDKALLICKRRG---DSYDLKDFVNLHSFQVRDDSSGDRDNKKWSHMFLLIEDQGAQGYELFFKTRELKKK--WMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCHRCRASAHKECLGRVPPCGRHGQDFPGTMKKDKLHRRAQDKKRNELGLPKMEVFQEYYGLPPPPGAIGPFLRLNPGDIVELTKAEAEQNWWEGRNTSTNEIGWFPCNRVKPYVHGPPQDLSVHLWYAGPMERAGAESILANRSDGTFLVRQR 698
BLAST of EMLSAG00000000123 vs. SwissProt
Match: gi|51338829|sp|Q9R0C8.2|VAV3_MOUSE (RecName: Full=Guanine nucleotide exchange factor VAV3; Short=VAV-3) HSP 1 Score: 175.637 bits (444), Expect = 5.774e-45 Identity = 144/591 (24.37%), Postives = 256/591 (43.32%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDA---ETEYIYDSFAKDIYNDTQDNYENIYQTICA--PKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGL-----NIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHCLGKIDVVEKTIKLMQLPRGAQLSD----------------------------FGRLRKAGELTAEN-SYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPL---FHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIG 571
M WK+C WL + KV+PP H++ T ++++ D +RDGVLLCQL+++L P S+++ + SQ F+C NI FL A F + E FE DL+ ++ G VIETLS LS + + FP +E N+E+IY + ++ + + E +YD + ++ + YE++ + A PK+Q + R + E+ TE+KY E L + F L L++ + + +F + +L+++H ++ + N + ++F+ + +YG YC + ++ + + K ++ +L C +A F L L++P QR LK ++ ++V H ++ + L + AQ + FGR + GE+ + + FLFD +++C R Y + + ++ Y+I + + F+ I L F C+ ++ W + A+ + P H M TF TSC C ++ G F+QGY C +C A HK+C+G
Sbjct: 1 MEPWKQCAQWLIHSKVLPPNHRV--TWDSAQVFDLAQTLRDGVLLCQLLNNLRPHSINLKEINLRPQMSQ-------FLCLKNIRTFLAACCDTFGMRKSE-LFEAFDLFDVRDFGKVIETLSRLSRTPIALATGIRPFPTEES------INDEDIYKGLPDLIDETRVEDEEDLYDCVYGE--DEGGEVYEDLMKAEEAQQPKSQENDI------------RSCCLAEIRQTEEKYTETLESIEKYFMAPLKRFLTAAEFDSVFINIPDLVKVHRSLMQEIHDSIVNKDDQNLYQVFINYKERLV-IYGQYCSGVESAISNLDYISKTKEDVKLKLEECSKRANNGKFTLRDLLVVPMQRVLKYHLLLQELVKHTHDPMEKANLKLALDAMKDLAQYVNEVKRDNETLREIKQFQLSIENLNQPVLLFGRPQGDGEIRITTLDKHTKQERHIFLFDLAVIVCKRKG---DNYEMKEIIDLQQYKIANNPTTDKENKKWSYGFYLIHTQGQNGLEFYCKTKDLKKKWLEQFEMALSNIRPDYADSNFHDFKMHTFTRVTSCRVCQMLLRGTFYQGYLCFKCGAKAHKECLG 557
BLAST of EMLSAG00000000123 vs. SwissProt
Match: gi|12643372|sp|Q9UKW4.1|VAV3_HUMAN (RecName: Full=Guanine nucleotide exchange factor VAV3; Short=VAV-3) HSP 1 Score: 169.859 bits (429), Expect = 6.123e-43 Identity = 142/589 (24.11%), Postives = 248/589 (42.11%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDA---ETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGL-----NIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHCLGKIDVVEKTIKLMQLPRGAQLSD----------------------------FGRLRKAGELTAEN-SYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPL---FHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIG 571
M WK+C WL + KV+P H++ T ++++ D +RDGVLLCQL+++L S+++ + SQ F+C NI FL A F + E FE DL+ ++ G VIETLS LS + + FP +E N+E+IY + ++ + + E +YD +Y +D +Y+ + + E R + E+ TE+KY E L + F L L++ + + +F + EL++LH ++ + N + ++F+ + +YG YC + ++ + + K ++ +L C +A F L L++P QR LK ++ ++V H + + L + AQ + FGR + GE+ + + FLFD +++C R Y + + ++ Y+I + + F+ I L F C+ ++ W + A+ + P H M TF TSC C ++ G F+QGY C +C A HK+C+G
Sbjct: 1 MEPWKQCAQWLIHCKVLPTNHRV--TWDSAQVFDLAQTLRDGVLLCQLLNNLRAHSINLKEINLRPQMSQ-------FLCLKNIRTFLTACCETFGMRKSE-LFEAFDLFDVRDFGKVIETLSRLSRTPIALATGIRPFPTEES------INDEDIYKGLPDLIDETLVEDEEDLYDC----VYG--EDEGGEVYEDLMKAE------EAHQPKCPENDIRSCCLAEIKQTEEKYTETLESIEKYFMAPLKRFLTAAEFDSVFINIPELVKLHRNLMQEIHDSIVNKNDQNLYQVFINYKERLV-IYGQYCSGVESAISSLDYISKTKEDVKLKLEECSKRANNGKFTLRDLLVVPMQRVLKYHLLLQELVKHTTDPTEKANLKLALDAMKDLAQYVNEVKRDNETLREIKQFQLSIENLNQPVLLFGRPQGDGEIRITTLDKHTKQERHIFLFDLAVIVCKRKG---DNYEMKEIIDLQQYKIANNPTTDKENKKWSYGFYLIHTQGQNGLEFYCKTKDLKKKWLEQFEMALSNIRPDYADSNFHDFKMHTFTRVTSCKVCQMLLRGTFYQGYLCFKCGARAHKECLG 557
BLAST of EMLSAG00000000123 vs. SwissProt
Match: gi|115305910|sp|Q45FX5.1|VAV_CAEEL (RecName: Full=Protein vav-1) HSP 1 Score: 153.68 bits (387), Expect = 1.516e-37 Identity = 161/667 (24.14%), Postives = 269/667 (40.33%), Query Frame = 0
Query: 26 LWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLN-TDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENI--YQTICAPKT-----QRFSLEIFGSSLKSKS--------------KRDLPINELIDTEDKYL-ENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGLN--IKGS--------------------QVGEIFLRL-NPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQL--FTCQAKARPTTFPLTSHLILPFQRFLK------------------------NSEMIIDIV---------IHCLGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENS----YGARLSDYAFLFDTIILLC-----------TRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPLFHRIVPH------------PTPHLLFVCRNAADREVWRKAITDAVDVVEPKENA-ERGHVLAMTTF----KEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEV 578
LW C WL + KV L T N + +F +++RDG+LLC+L ++L P+ +D +++ + S F+C +NI F A+ Y N D F EDLY V++TLS LSH + V FP + N + S+ E D E IY DN EN+ +TI P T ++ S +++ + ++ KR+ I EL DTE Y+ + L+ + F + L ++ + D +IF ++E+ LHT +L L +K + +GE+F++ + +A YG YC +LP S L K + + + T Q + F + L +PFQR K E++ D+ + + ID +E++I + +P +L D+GR+ GE+ S G Y FLFD +I++C T + + ++ A + + I + + S R + L F +N A R W A+ + V P + + H +A +F K +C C+++M G+ +QGY+C+ C +HK+C+G C V
Sbjct: 39 LWIGCARWLRDMKV-------LTTDKNGTMLEFASVLRDGILLCRLANTLVPNGIDQKKIMRT-------NQPSPFLCCNNINYF--AMFCKTYFNLEDADLFTAEDLYYMNGFQKVLKTLSFLSHTKESLSRGVDPFPDTD--------NNQEGTSNGSEFEDDVE-----------IYQSLHDNIENVDPNRTIYGPITSADPEEQQSEQLYDRIVTNRKPSMNENDLQNTPTLKRNRCIRELYDTEKNYVAQALVTIIKTFYEPLKGIIPTSDYNIIFGNIEEINVLHTALLADLEYPVKVALGLSDATPPRPISLNECVPQTIGEVFIKYRDQFLA--YGKYCSNLPDSRKLSNELLKTNEFISRNINELTAQGNCK---FGMNDLLCVPFQRLTKYPLLLKELQKKTDLASPDRKSLEEAVEVMEDVCNYINEESRDTNAIKVIDEIEQSITDLSMPLNVKLHDYGRVNLDGEVKMAESTLTQAGKPKQRYIFLFDKVIVVCKAANKVMAAKTTGASARTNTFTYKNAYVMSELTIDKNASLDVKSGGTITRRTQYVIIMTRDRNENNEITQLTFYFKNEATRNNWMTALLLSKSNVSPTDYLRDTNHKVAFHSFRVDVKNPATCDVCDKLMKGLQYQGYKCESCNMSMHKECLGLKKCEAV 665
BLAST of EMLSAG00000000123 vs. Select Arthropod Genomes
Match: AAN09485.1 (Vav guanine nucleotide exchange factor, isoform B [Drosophila melanogaster]) HSP 1 Score: 213.772 bits (543), Expect = 1.341e-58 Identity = 202/722 (27.98%), Postives = 319/722 (44.18%), Query Frame = 0
Query: 17 GNTQSFNMVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKR--SSVPGF-----PKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTLLSSKDK-ELIFYKLDELIRLHTEILTGL------NIKGSQVGEIFLRL-NPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK------------------------NSEMIIDI------VIHCLGKIDVVEKT------IKLMQLPRGAQLSDFGRLRKAGEL--TAENSYGARLSDYAFLFDTIILL--CTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHP---NSIPLFHRIVPHPTPHLLFV--CRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGSTNSNASSINNNGLTKCDSVTLPTVINEPLERSESTLSLSPDSKQPSADRVSKLQRETEEELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVRKR 678
G N LW+ECVAWL KVIPP HK Q ++++ +RDGVLLC LV LDPSS+D R P+ + F+C NI LFL +NF + D FEP LY N V+ TLS LS C KV++ + GF P + H ++E IY K+++ + Y+ T E +YQ +CA R S SS S +RD I ELIDTE YL+ L ++ F L ++D+ LIF ++ EL+ +HT+ L L N K ++ ++FL P + +YG++C L ++D++ + K++ + + C+ L L +P QR LK E +ID+ V + +++K I L+Q G+ L +GRL GEL A +L YAF+FD I+++ K +Y +R + + DYR+ Q+ ++ + ++ + F ++ +R+ WRKA+T+A++ +EP H + + TF T+C C++ + G QGYRC+ CQ +HK C I++ G K + V++P P DR + +WFAG+++ +TA+ RL++ +GT+L+R R
Sbjct: 11 GGVAGVNGDLWRECVAWLTRCKVIPPDHKAAQP--DAEIRILAMTLRDGVLLCNLVIHLDPSSLD-PREFNRKPQ------MAQFLCSKNIKLFLDVCHNNFGIR-DADLFEPTMLYDLTNFHRVLITLSKLSQCRKVQQLHPDLIGFNLQLSPTERSH------SDEAIY---KDLHSTTTDNIACNGTG---YDHTNTKEEEVYQDLCA--LHRTSRSQTASS-TSFEQRDYVIRELIDTESNYLDVLTALKTKFMGPLERHLNQDELRLIFPRIRELVDIHTKFLDKLRESLTPNAK-VKMAQVFLDFREPFL--IYGEFCSLLLGAIDYLADVCKKNQIIDQLVQKCERDYNVGKLQLRDILSVPMQRILKYHLLLDKLVKETSPLHDDYRSLERAKEAMIDVSQYINEVKRDSDHLVIIQKVKDSICDIHLLQNGNGSDLLQYGRLLLDGELHIKAHEDQKTKLR-YAFVFDKILIMVKALHIKTGDMQYTYRDSHNLADYRVEQSHSRRTIGRDTRFKYQLLLARKSGKTAFTLYLKSEHERDKWRKALTEAMESLEPPGCQSTDHKMEIYTFDAPTTCRHCSKFLKGRIHQGYRCKVCQISVHKGC------------------ISSTGRCKQNPVSVPP---------------------PVCDR---------------QLSEFNWFAGNMDRETAAHRLENRRIGTYLLRVR 649
BLAST of EMLSAG00000000123 vs. Select Arthropod Genomes
Match: AAF48943.3 (Vav guanine nucleotide exchange factor, isoform A [Drosophila melanogaster]) HSP 1 Score: 213.772 bits (543), Expect = 1.341e-58 Identity = 202/722 (27.98%), Postives = 319/722 (44.18%), Query Frame = 0
Query: 17 GNTQSFNMVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKR--SSVPGF-----PKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTLLSSKDK-ELIFYKLDELIRLHTEILTGL------NIKGSQVGEIFLRL-NPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK------------------------NSEMIIDI------VIHCLGKIDVVEKT------IKLMQLPRGAQLSDFGRLRKAGEL--TAENSYGARLSDYAFLFDTIILL--CTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHP---NSIPLFHRIVPHPTPHLLFV--CRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGSTNSNASSINNNGLTKCDSVTLPTVINEPLERSESTLSLSPDSKQPSADRVSKLQRETEEELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVRKR 678
G N LW+ECVAWL KVIPP HK Q ++++ +RDGVLLC LV LDPSS+D R P+ + F+C NI LFL +NF + D FEP LY N V+ TLS LS C KV++ + GF P + H ++E IY K+++ + Y+ T E +YQ +CA R S SS S +RD I ELIDTE YL+ L ++ F L ++D+ LIF ++ EL+ +HT+ L L N K ++ ++FL P + +YG++C L ++D++ + K++ + + C+ L L +P QR LK E +ID+ V + +++K I L+Q G+ L +GRL GEL A +L YAF+FD I+++ K +Y +R + + DYR+ Q+ ++ + ++ + F ++ +R+ WRKA+T+A++ +EP H + + TF T+C C++ + G QGYRC+ CQ +HK C I++ G K + V++P P DR + +WFAG+++ +TA+ RL++ +GT+L+R R
Sbjct: 11 GGVAGVNGDLWRECVAWLTRCKVIPPDHKAAQP--DAEIRILAMTLRDGVLLCNLVIHLDPSSLD-PREFNRKPQ------MAQFLCSKNIKLFLDVCHNNFGIR-DADLFEPTMLYDLTNFHRVLITLSKLSQCRKVQQLHPDLIGFNLQLSPTERSH------SDEAIY---KDLHSTTTDNIACNGTG---YDHTNTKEEEVYQDLCA--LHRTSRSQTASS-TSFEQRDYVIRELIDTESNYLDVLTALKTKFMGPLERHLNQDELRLIFPRIRELVDIHTKFLDKLRESLTPNAK-VKMAQVFLDFREPFL--IYGEFCSLLLGAIDYLADVCKKNQIIDQLVQKCERDYNVGKLQLRDILSVPMQRILKYHLLLDKLVKETSPLHDDYRSLERAKEAMIDVSQYINEVKRDSDHLVIIQKVKDSICDIHLLQNGNGSDLLQYGRLLLDGELHIKAHEDQKTKLR-YAFVFDKILIMVKALHIKTGDMQYTYRDSHNLADYRVEQSHSRRTIGRDTRFKYQLLLARKSGKTAFTLYLKSEHERDKWRKALTEAMESLEPPGCQSTDHKMEIYTFDAPTTCRHCSKFLKGRIHQGYRCKVCQISVHKGC------------------ISSTGRCKQNPVSVPP---------------------PVCDR---------------QLSEFNWFAGNMDRETAAHRLENRRIGTYLLRVR 649
BLAST of EMLSAG00000000123 vs. Select Arthropod Genomes
Match: gb|KFM71930.1| (Guanine nucleotide exchange factor VAV2, partial [Stegodyphus mimosarum]) HSP 1 Score: 208.379 bits (529), Expect = 4.752e-57 Identity = 163/593 (27.49%), Postives = 276/593 (46.54%), Query Frame = 0
Query: 25 VLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYD-SFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENL-IMVRDVFRDQLTLLSSKDKELIFYKLDELIRLHT----EILTGLNIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNS------------------------EMIIDIVIH---------CLGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARLSD-YAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTS--PSHPNSIPL-FHRIVPHPT--PHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGD 572
LW+EC WL +V+ P H++ T ++++ D V +RDGVLLCQL++ L +D+ + SQ F+C NI FL + F + + + FEP L+ C + G V+ TLS LS +K + + + GFP K+ N+E IY +++EI E + + F + + E+IY+ +C T R ++ KRD I ELI+TE Y+E L ++++ R ++L++ +++IF + EL +HT E+ ++ E FL +YG+YC +LP + + + L + + + CQ +A F L L +P QR LK E ++D+ + L I ++ +I + +P +L D+GRL K GEL ++ RL + Y F+FD ++L+C + Q Y ++ A+ + DY++ + P N F+ ++ H L + + W +AI A+D V P H+ M +F + T+C C +++ G+F+QGY C C +HK CI D
Sbjct: 4 TLWRECADWLIKQQVLLPDHRV--TWPSAQVIDLVYTLRDGVLLCQLLNKLVIGCIDLKEISLRPQMSQ-------FLCLKNIRTFLQTCQNVFNIPSAD-LFEPAMLFDCTDFGKVLHTLSVLSKTDKAQAAGIKGFPSVIKN--HDYYNDE-IYRNLEEIANHNEEDTMVPLEFP---ISPRRSKEEDIYEDLCY-VTLRMREVSASQTVHPVEKRDYCIKELIETEKNYIEALNMIIKHFVRPLKSVLTADVRKVIFMNIKELAEIHTGFHSELYKACTSSHYKISECFLHWKDKFI-VYGEYCSNLPAAQERVEDLCNKSEVVNQAILRCQQEANGGKFKLRDLLSVPMQRILKYHLLLKELIRNTPKTHDDYFSLQKALEAMLDLAQYINEVKRDNETLQIIRDIQASITDLHMPDDLELKDYGRLLKDGELKIKSHDDHRLKNRYVFIFDKVMLMCKSTRGEQ--YSYKEALVLLDYKVEDVANTPKAGNRDKWSFYWLLAHKQNKTALTMYAKTEEMKRKWIEAIEKALDNVMPAALRSTDHIFQMHSFDKPTTCTECEKLLRGLFYQGYLCSVCGVAVHKDCIED 576
BLAST of EMLSAG00000000123 vs. Select Arthropod Genomes
Match: XP_006568541.1 (PREDICTED: protein vav isoform X2 [Apis mellifera]) HSP 1 Score: 203.756 bits (517), Expect = 4.444e-55 Identity = 164/605 (27.11%), Postives = 266/605 (43.97%), Query Frame = 0
Query: 19 TQSFNMVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICA---------PKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGLNIK--GSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK-------------------------NSEMIIDIVIH---------CLGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARL-SDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHP---NSIPLFHRIVPHPTPHLLFV--CRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIG 571
+ S N W ECV WL + HK P + + D +RDGVLLC L++++DP +DM V +Q F+C NI +FL A + F L TD FEP L+ + V+ TLSALS+C +++R + GF +++E+IY ++ G T + K D ++ +YQ + P T++ ++ KRD I EL++TE Y + L + F L+ LL +D IF+ + EL +H + L G+ + ++FL +YGDYC +L + + + + + ++ CQ +A F L L +P QR LK E+++DI + L I ++ +I +P QL DFGRL + GEL + RL + Y F+F+ ++L+C + Q Y +R +++ DYR+ + +S + ++ H + + R +++W KA+ DA+D V P H +TTF SC C + + G FQGYRC+ C +HK+CI
Sbjct: 6 SSSDNGSGWHECVKWLTRCGALRADHKA-NWPEATAV-DLAYTLRDGVLLCNLLNTVDPGCIDMKDVNQKPQMAQ-------FLCLRNIKVFLSACSTIFGL-TDSELFEPSMLFDLSDFLRVLRTLSALSNCPRLRRKGILGFSISHG------RSQEDIYKDLQSA-GAGPTTGVGTFTMKPKVMDVDES--QVYQELLCFSSNSQHDWPSTEK------DGAISGGEKRDYVIQELVETERNYSDVLNSLLKYFARPLSSLLRPEDSTRIFFGIKELAEIHAGFHSQLRKARTGAALAQVFLDWREKFL-IYGDYCANLTLAQNTLQEACARNELVNQEVIRCQQEANNGKFKLRDILSVPMQRVLKYHLLLDKLVEETPCDWLEDRRQLAKAREVMVDIAQYINEVKRDSDTLDIIRDIQASIIDWDVPEDTQLKDFGRLLRDGELKVKAHGDQRLKARYVFVFEQVVLICKAGRGEQ--YCYRETLRLDDYRLEDHTGRRTLGRDSRWSYQWLLVHKQEYTAYTLHARTEEQKQMWMKALQDAMDNVNPAACRNTNHKFKLTTFNTPRSCQRCGKFLKGRIFQGYRCEACCYAVHKQCIA 582
BLAST of EMLSAG00000000123 vs. Select Arthropod Genomes
Match: XP_006568540.1 (PREDICTED: protein vav isoform X1 [Apis mellifera]) HSP 1 Score: 202.986 bits (515), Expect = 9.470e-55 Identity = 167/617 (27.07%), Postives = 267/617 (43.27%), Query Frame = 0
Query: 19 TQSFNMVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDT------------QDNY---------ENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGLNIK--GSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK-------------------------NSEMIIDIVIH---------CLGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARL-SDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHP---NSIPLFHRIVPHPTPHLLFV--CRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIG 571
+ S N W ECV WL + HK P + + D +RDGVLLC L++++DP +DM V +Q F+C NI +FL A + F L TD FEP L+ + V+ TLSALS+C +++R + GF +++E+IY ++ E E F + N+ +D Y E IYQ +C+ ++ KRD I EL++TE Y + L + F L+ LL +D IF+ + EL +H + L G+ + ++FL +YGDYC +L + + + + + ++ CQ +A F L L +P QR LK E+++DI + L I ++ +I +P QL DFGRL + GEL + RL + Y F+F+ ++L+C + Q Y +R +++ DYR+ + +S + ++ H + + R +++W KA+ DA+D V P H +TTF SC C + + G FQGYRC+ C +HK+CI
Sbjct: 6 SSSDNGSGWHECVKWLTRCGALRADHKA-NWPEATAV-DLAYTLRDGVLLCNLLNTVDPGCIDMKDVNQKPQMAQ-------FLCLRNIKVFLSACSTIFGL-TDSELFEPSMLFDLSDFLRVLRTLSALSNCPRLRRKGILGFSISHG------RSQEDIYKDLQSAGAGREDEDRRRRFRRREGNEAGGGGDNEDPVEEEDGYGAYCSHAQSEEIYQDLCSLHLPPPPSVAQDGAISGGEKRDYVIQELVETERNYSDVLNSLLKYFARPLSSLLRPEDSTRIFFGIKELAEIHAGFHSQLRKARTGAALAQVFLDWREKFL-IYGDYCANLTLAQNTLQEACARNELVNQEVIRCQQEANNGKFKLRDILSVPMQRVLKYHLLLDKLVEETPCDWLEDRRQLAKAREVMVDIAQYINEVKRDSDTLDIIRDIQASIIDWDVPEDTQLKDFGRLLRDGELKVKAHGDQRLKARYVFVFEQVVLICKAGRGEQ--YCYRETLRLDDYRLEDHTGRRTLGRDSRWSYQWLLVHKQEYTAYTLHARTEEQKQMWMKALQDAMDNVNPAACRNTNHKFKLTTFNTPRSCQRCGKFLKGRIFQGYRCEACCYAVHKQCIA 603
BLAST of EMLSAG00000000123 vs. Select Arthropod Genomes
Match: gb|EEZ97169.2| (Protein vav-like Protein [Tribolium castaneum]) HSP 1 Score: 189.119 bits (479), Expect = 4.872e-50 Identity = 168/618 (27.18%), Postives = 268/618 (43.37%), Query Frame = 0
Query: 23 NMVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEI---LTGLNIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK--------------NSEMIIDI------VIHCLGKIDVVEKTIKLMQLPRGAQ-------------LSDFGRLRKAGELTAENSYGARLSD-YAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPL-----FHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGSTNSNASS-INNNGLTKC 596
N LWKEC WL + ++ H+ P ++ ++D ++RDGVLLC+L++ + P +DM V +Q F+ HNI LFL V +F L D+ F+P L+ N V+ TLS LS + ++S++ GF + K K E+ IY S+K + + D IY+ E IYQ +CA + + F KRD I EL+DTE Y+E L ++ F L + +D E++FYK+ +L +H LT G ++ IF+ +YG YC +L R+ + + L D A + + + F L L +P QR LK N E D+ ++ G I+ + + + + + Q L ++GRL K GE+ + ++ + Y F+FD IL+C + K Q + FR + I +Y + T S FH + R ++ KAI DA+D + P H + TF C+ C++ + G+ +QGY+C C +HK CI GS N +++S + NG C
Sbjct: 12 NDELWKECSKWLTRWGMLRADHRA-NWP-DACIADLANILRDGVLLCKLLNKISPGCIDMKNVNLKPAMAQ-------FLSLHNIELFLKTCVISFGL-KDQDLFDPLVLFELTNFHKVLCTLSKLSLTKEAQKSNILGFTAQ----GVKTKEEDVIYQSLKSVEMPTNARGMNDP----IYDVAG---EEIYQDLCALRPVNEQPQTF-------EKRDFVIKELLDTEKNYVEVLAKLKRNFMKPLANQMKPQDHEVVFYKIYDLHEIHLAFYRELTRFRDPGFRLSSIFMNWRERFL-VYGGYCANLTRATNLLQELCDCDENFNATIVAYEKEDNNGRFKLRDVLSVPMQRILKYHLLLEKLIENTDPNDEECNDLRRAREAMLDVAGFINEAARDSEHLAVIQNLQENIVEWYRSPDHRLVNYGRLIKDGEMKIKAHDDQKIRNRYVFIFDKCILICKQIKVRQ--FAFRNIINISEYHVDDTHNRAVLSRDARFCYHFHLVKNDNVMVYTIFVRTLELKQQMIKAINDALDNIHPAAIKRTNHTFELQTFNGPVQCFHCSKYLRGLIYQGYKCGVCGIGVHKHCIAHSG--RCGSHNHHSTSDLVMNGADAC 596
BLAST of EMLSAG00000000123 vs. Select Arthropod Genomes
Match: EAA14588.5 (AGAP010292-PA, partial [Anopheles gambiae str. PEST]) HSP 1 Score: 189.119 bits (479), Expect = 5.193e-50 Identity = 162/595 (27.23%), Postives = 266/595 (44.71%), Query Frame = 0
Query: 26 LWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSS-VPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQL-TLLSSKDKELIFYKLDELIRLHTEILTGLN---IKGSQV--GEIFLRL-NPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK------------------------NSEMIIDIVIHC---------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARLSD-YAFLFDTIILLC--TRPKWLQHRYRFRTAVKIRDYRIGQTSPSHP---NSIPLFHRIVPHPTPHLLFV--CRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIG 571
LW+EC AWL +IP H+ +S + ++RDGVLLC L + DPSS D + P+ + F+C NI LFL A +NF L + FEP LY N V+ TLS LS C KV+ ++ +PGF ++ +++IY K+++ Y S +++ E +YQ +C+ Q S SS + +RD I EL+DTE YLE L ++ +F L LLS ++ IF + EL+ +H + L L+ GS++ FL P + +YG+YC + +++ + K+ + + Q + L L +P QR LK E ++D+ + L I V+++I + LP G L +GRL G+L + ++ YAF+F+ +++L + K + +Y FR A + DYRI + + + ++ T F + +RE W++A A++ +EP H + TF C C++ + G QGYRC+ C+ ++H+ CI
Sbjct: 15 LWRECAAWLTRCNIIPNDHR--ANHLDSDIKVLATILRDGVLLCNLANFFDPSSFD-RKDFNRKPQ------MAHFLCIQNIKLFLEACKTNFGLK-EADLFEPTMLYDLTNFHRVLLTLSKLSTCRKVQTATNIPGFITHSVQ-TERTSLDDDIY---KDLHASTSNPVEYCS-----HDEHDMKVEEVYQDLCS--IQNASRNQVSSSSNNLEQRDFVIKELLDTEKNYLEALNALKYIFMQPLEKLLSKEEIRAIFPCIRELVEIHNKFLDRLHEAVCPGSKLKLSTTFLEFREPFL--IYGEYCSSMTSAVETLREACKKSNTVEQTVLQSQKEHSDGRLQLRDILSVPMQRILKYHLLLDKLVQETVPTHDDFRGLERAKEAMVDVAQYSNEVKRDSEHLIVIQKVKESISDLNLPNGNNLEQYGRLLLDGDLNIKAHEDQKMKHRYAFVFEKVMILVKNSNTKIGEAQYSFREAHNLLDYRIEILNSRRTLGRDGRLKYSLLLARKTQATAFTLYMKTEEEREKWKRAFETAMETLEPVGCKNTDHKFVIHTFDTPVICRHCSKFLKGKIHQGYRCKVCEIVVHRGCIS 586
BLAST of EMLSAG00000000123 vs. Select Arthropod Genomes
Match: EEB17268.1 (protein vav, putative [Pediculus humanus corporis]) HSP 1 Score: 178.333 bits (451), Expect = 2.022e-46 Identity = 161/603 (26.70%), Postives = 263/603 (43.62%), Query Frame = 0
Query: 27 WKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSL-KSKSKRDLPINELIDTEDKYLENLI-MVRDVFRDQLTLLSSKDKELIFYKLDELIRLHTEILTGLNIKGSQVGEIFLRLNPIIAR------LYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK------------------------NSEMIIDIVIH---------CLGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGEL--TAENSYGARLSDYAFLFDTIILLCTRPKW-LQHRYRFRTAVKIRDYRIGQTSPS--HPNSIPLFHRIVPHPTPHLLFVC--RNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGST 581
W+EC WL ++ H + +K D +RDGV+LC L++ ++P +D V SQ R + F R F FL F L + F+P L+ + V++TLS LS K K+ ++ GF L K + + +Y + + Y S ++ N E IY +C+ R SL+ S+L S KRD INELI+TE YL+ L + R R +++ +D ++IF + EL +H LT L S G+I RL+ + +YGDY +L + + I L + ++ CQ +A F L L +P QR LK E ++D+ + L + +E++I +P L D+GRL GEL A N ++ Y F+FD ++++C K L +Y +R ++++ +Y+I ++ + + H + C R ++ + AI++A+D +EP H M TF+ T+C C++ + G +QGY+C++C HK CI C GST
Sbjct: 8 WRECADWLTRCGILRSDH--IANGAEAKARDLAVTLRDGVILCNLLNDIEPGCIDTKDV------SQKPRLSQVF--RVTTFFFLQTSHDTFGLKESD-LFDPVVLFDLTDFVKVLQTLSKLSLSPKFKKKNISGFS-----LIKHRSSHDELYKDLIHSNVLRAEDAEYSSHHVNMRN------EEIYHDLCS--INRISLQQIPSALPASLEKRDYVINELIETERNYLDVLGGLQRSFMRPLASIIREEDFKIIFAHIKELYEIHGVFLTQLRKAASPHGKI--RLSEVFLSFREKFLIYGDYIANLTNAQNLIQDLCGRSEMINNEVENCQQEANNGKFKLRDILSVPMQRILKYHLLLDKLVSETQMNHEDYRGLERAKEAMVDVAQYINEVKRDSDALAILAYIEQSISDWHMPPDFTLKDYGRLILDGELRIKAHNDQKQKVR-YVFVFDRVMVMCKALKTILGDQYCYRESLRLDEYKIQDIEKKILTRDARWSYQWYLVHRAELTAYTCYSRTEEFKKKFMNAISEALDNIEPSVCRNTEHNFKMFTFESPTTCSHCSKFLKGKIYQGYQCEKCHINCHKICIP--YCGRCGST 581
BLAST of EMLSAG00000000123 vs. Select Arthropod Genomes
Match: EFX75144.1 (hypothetical protein DAPPUDRAFT_323685 [Daphnia pulex]) HSP 1 Score: 178.333 bits (451), Expect = 2.235e-46 Identity = 177/718 (24.65%), Postives = 301/718 (41.92%), Query Frame = 0
Query: 15 IGGNTQSFNMVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKS-KRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGLNIKGSQVGE------IFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK--------------NSEMIIDIVIHCLGKIDVVEKT------IKLMQLPRGAQLS-------------DFGRLRKAGEL---TAENSYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNS-------IPLFHRIV----PHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGSTNS-NASSINNNGLTKCDSVTLPTVINEPLERSESTLSLSPDSKQPSADRVSKLQRETEEELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVR 676
+ G++Q + LW+ECV WL K++ Q P NS+L F IRDG +LC L+ LDP+++D V SQ ++ NI LFL A + F L D FEP L+ + G V+ TLS LS C+KV + + GFP + +++ ++ IY +++I E +Y ++A ENIY+ +C+ S + + KR+ I EL+++E +Y+E L M++ F L+ +L +K+ +F+ ++EL +HT + + L IK +FL +YG C +L + I ++ ++ CQ +A L + LP QR LK + E D+ + +D+ + T ++ Q+ + Q S ++GRL K GEL + E S A+ + Y FLF+ +Y F+ + + +++ HP S I H+ + + T + L+ ++A + W A ++ ++ + P E+ H TF SC+ C +++ G F QGYRC +C +H++C+G TNS +T P + LER WF+G++ A L++ P+GT+L+R
Sbjct: 1 MAGSSQ--RVPLWRECVDWLDRLKILRSD----QFPPNSELIHFGQCIRDGFILCYLITKLDPNALDFHDVCQRTQMSQ-------YMSLKNIRLFLRACRNKFDL-ADSDLFEPAMLFDYTDFGKVLRTLSKLSKCSKVTQKGIEGFPAVD---SRQYVEDDEIYRRLEDI-DQQEDQYCEYNYAV--------TGENIYEELCSVGEHNKSPQTHHPFPQPPVVKREYSIRELVESEKRYIEALSMIKTNFIVPLSSVLREDEKKCVFHGIEELHEIHTGLYSDL-IKACTTNNTIKLHMVFLNWKDKFL-IYGSICSNLSSARRAIKSAICRSREVAEKIERCQREASEVALNLEDLITLPMQRLLKYPLLLGNLCKHTEKSHEDYHDLQLAYEAMVDIADYTNESTRDYEMRQIIKDVQASISNWNTMENCDLVEYGRLIKDGELKMRSHEESRNAK-TRYVFLFNX-----------GDQYSFKLFLSLEKFKL----EDHPTSRNQNGREIRWSHQWLLVDNQNKTAYTLYA-KSAEAKNKWIGAFSETLEKLNPAESWGSDHNYEFHTFSNSISCHFCKKLLKGSFLQGYRCNKCSVSVHRECLG-------SMTNSCGVPIPPPRPRQIGAKLTSPAFHHIDLER-------------------------------------YPWFSGEMTRTAAEAVLRNTPLGTYLLR 629
BLAST of EMLSAG00000000123 vs. Select Arthropod Genomes
Match: XP_006568542.1 (PREDICTED: protein vav isoform X3 [Apis mellifera]) HSP 1 Score: 139.043 bits (349), Expect = 1.932e-33 Identity = 106/403 (26.30%), Postives = 175/403 (43.42%), Query Frame = 0
Query: 212 ENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGLNIK--GSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK-------------------------NSEMIIDIVIH---------CLGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARL-SDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHP---NSIPLFHRIVPHPTPHLLFV--CRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIG 571
E IYQ +C+ ++ KRD I EL++TE Y + L + F L+ LL +D IF+ + EL +H + L G+ + ++FL +YGDYC +L + + + + + ++ CQ +A F L L +P QR LK E+++DI + L I ++ +I +P QL DFGRL + GEL + RL + Y F+F+ ++L+C + Q Y +R +++ DYR+ + +S + ++ H + + R +++W KA+ DA+D V P H +TTF SC C + + G FQGYRC+ C +HK+CI
Sbjct: 69 EEIYQDLCSLHLPPPPSVAQDGAISGGEKRDYVIQELVETERNYSDVLNSLLKYFARPLSSLLRPEDSTRIFFGIKELAEIHAGFHSQLRKARTGAALAQVFLDWREKFL-IYGDYCANLTLAQNTLQEACARNELVNQEVIRCQQEANNGKFKLRDILSVPMQRVLKYHLLLDKLVEETPCDWLEDRRQLAKAREVMVDIAQYINEVKRDSDTLDIIRDIQASIIDWDVPEDTQLKDFGRLLRDGELKVKAHGDQRLKARYVFVFEQVVLICKAGRGEQ--YCYRETLRLDDYRLEDHTGRRTLGRDSRWSYQWLLVHKQEYTAYTLHARTEEQKQMWMKALQDAMDNVNPAACRNTNHKFKLTTFNTPRSCQRCGKFLKGRIFQGYRCEACCYAVHKQCIA 468
BLAST of EMLSAG00000000123 vs. nr
Match: gi|669193707|gb|AII16559.1| (vav 2 oncoprotein, partial [Paracyclopina nana]) HSP 1 Score: 619.387 bits (1596), Expect = 0.000e+0 Identity = 345/717 (48.12%), Postives = 453/717 (63.18%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDI-YNDTQDNY--ENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTLLSSKDKELIFYKLDELIRLHTEILTGLNI-KGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK--------------------NSEMIIDIVIHCLGKID------------------------VVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNS--------IPLFHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGSTNSNASSINNNGLTKCDSVTLPTVINEPLERSESTLSLSPDS----KQPSADR--VSKLQRETEEELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVRKR 678
M L +E AWL +FK+IPPG L+ N+ LSD +A++RDGV+LCQLVHSLDPSSV+M +VI E +GRS SDF+CR+NIFLFLHA V+NF L ++ F PEDLY C++IG V TLS LSH KV +S PGFPKKEK L K++KNE + Y +++++YG+A TEYIYDSFA I D +D Y E+IYQTI P+ R SL KSKR PI+EL+ TEDKYLENLIMVRDVFR++LT+++ +DK +IFY LD+LI LH++IL GL K +G++FLRL P I LYG YCVHLP +M + L + L+ Q+ CQA A P+TFPL+SHL++PFQRFLK N + +D +I +++ V TIKLM++ G L ++GRLR+AG++ + +G R+ DYAFLFD +I+LC RPKWLQHRYRFR A+KIRD + P H + LF + L V R+AADRE W AI A+D V P EN+++GHV+ +TTF E T C+ C +++ G FFQGY+C RCQA +HK C+ D CLEVG+ L K +S+ LPT + E LERS STLSL+P S K+ S R V +LQ E ++P++ Q W+AG+L+ KTAS RL+SLPVGTFL+RKR
Sbjct: 1 MELHREISAWLDHFKLIPPGSPALRP--NASLSDVIAVLRDGVVLCQLVHSLDPSSVEMHKVIC---EDGSGRSVSDFLCRNNIFLFLHAAVANFEL-SEGQLFHPEDLYQCRDIGKVFRTLSELSHTPKVLKSGAPGFPKKEKQLYKRLKNERSNYEALEQMYGEAGTEYIYDSFASKIRLRDQEDLYYNEDIYQTIFPPRQPRLSLADISFGGTKKSKRSAPIHELLTTEDKYLENLIMVRDVFREKLTIMNIQDKNIIFYLLDDLILLHSDILFGLKTPKKDDIGKVFLRLLPRITHLYGCYCVHLPMAMAHLEHLSQNYAPLKKQILECQAHANPSTFPLSSHLVIPFQRFLKYHLLLQEILKRTPDDHPDYVNLRLAVDEMIKAGEQVNEKKREQEEADQQDTKDEADMRLILSVSSTIKLMKMENGLNLLNYGRLRRAGDIVSYTDHG-RVGDYAFLFDLMIVLCHRPKWLQHRYRFREAIKIRDNFL--EPPIHHQQQQGQDVFCLRLFSKADARRVT-LTLVSRSAADREAWFDAILTAMDTVNPSENSQQGHVIQLTTFTEPTECFQCGKLLRGRFFQGYKCLRCQACMHKVCLADCACLEVGAP-----------LKKSNSLMLPTAMPESLERSTSTLSLAPSSENGNKRHSQIREVVQELQFNAIREQESLPLDEQPWYAGELDVKTASDRLESLPVGTFLIRKR 696
BLAST of EMLSAG00000000123 vs. nr
Match: gi|919059922|ref|XP_013411705.1| (PREDICTED: proto-oncogene vav-like isoform X6 [Lingula anatina]) HSP 1 Score: 229.18 bits (583), Expect = 1.296e-60 Identity = 167/599 (27.88%), Postives = 284/599 (47.41%), Query Frame = 0
Query: 26 LWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICA------PKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQL-TLLSSKDKELIFYKLDELIRLHTEILTGLN-----IKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNS------------------------EMIIDIVIHC---------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARL-SDYAFLFDTIILLC---TRPKWL-QHRYRFRTAVKIRDYRIGQTSPS-HPNSIPLFHRIVPHPTPHLL---FVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCI 570
LW+ C WL +++P H+++ N+++ D +RDGVLLC L+++L P +VDM SQ F+C NI FL + F L + F+ DL+ ++ V+ TLS LS S + GFP+ I+ E + Y++++E+ + E IY + ++ + IY+ +C+ + + + + K+KR+ + ELI+TE Y+E L M++ F L ++ S + ELIF ++ L +HT + L+ +G+ F++ P + LYGD+C +LP++ + I L +++ +R + CQ KA F L L +P QR LK E + D+ ++ L I ++ +I +Q+P L D+GRL K GEL ++ RL + Y FLFD ++L+C T K+L Y ++ A+ + +R+ + P+ P S H + + + F + + W AI A+D P E+GH MTTF+E +C C +++ G+F+QGY C RC+ +HK+CI
Sbjct: 6 LWRLCADWLIRCEILPRDHRVMFP--NAEIFDLAQTLRDGVLLCHLLNTLSPGAVDMKDFSQRPQMSQ-------FLCLKNIRTFLQTCKNKFGLRESD-LFDSYDLFDVKDFAKVLNTLSKLSKSELALASGIDGFPQDNS----SIQVEHDYYNTLEELATELPDEDIYSAVTT-----VEEGEQEIYEDLCSLRGRTTRRRKERERDQLEQGFEPKTKREHCLKELIETEKNYVEALQMIKTFFIHPLKNIIPSPNHELIFKHIEGLGNIHTAFQSDLHQAVRRSSAQALGDCFIKYKPQLL-LYGDFCSNLPQAQERIDDLCRKNEIIRVAVEECQRKANEGKFRLRDLLSVPVQRVLKYHLLLKELIKQTDKKSPDRTFLEKALEAMQDLSLYVNEVKRDNEQLQLIQEIQDSIVDLQMPEKTSLKDYGRLLKDGELKIKSHEDNRLKTRYIFLFDKVMLMCKSRTMEKFLWGETYSYKNALVLAQHRVEEGVPAGRPRSEKWGHVFLLSENKNSVAYNFYAKTEEMKMKWVDAIKMALDNTNPANAREKGHDFIMTTFEEPQTCSECKKLLRGVFYQGYNCHRCKQSVHKECI 584
BLAST of EMLSAG00000000123 vs. nr
Match: gi|391339789|ref|XP_003744229.1| (PREDICTED: protein vav [Galendromus occidentalis]) HSP 1 Score: 226.868 bits (577), Expect = 4.095e-60 Identity = 192/724 (26.52%), Postives = 316/724 (43.65%), Query Frame = 0
Query: 25 VLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNY------ENIYQTIC-----APKTQRFSLEIFGSSLKSK-SKRDLPINELIDTEDKYLENLIMVRDVFRDQL-TLLSSKDKELIFYKLDELIRLHTEILTGLNIKG----SQVGEIFLRL-NPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK--------------------NSEMIIDIVIHCLGKIDVVEKTIKLMQ-------------LPRGAQLSDFGRLRKAGELTAENSYGARLSD-YAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPLFHRIVPHPTPHLLFV-------------CRNAADREVWRKAITDAVDVVEPKENAERGHV-LAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGSTNSNASSINNNGLTKCDSVTLPTVINEP-LERSESTLSLSPDS-----KQPSADRVSKLQRETEEELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVR 676
VLW+E V WL + ++IP H++ T ++++ + +RDGV+LC L L P +D + SQ F+C NI FL A+ + F + + FEPE L+ + V+ +LS LS+ + + V GF K + N E Y + D T + SF + N + E IY IC APK + I L+ KRDL I EL++TE Y++ L M+R F+ L +S D +IF + L +HT +L L++ ++ E FLR N +I +YG+YC + PR+ + L ++ + + CQ + + L + L +P QR LK E +D ++ I+ V++ +++Q LP+ L D+GRL K GE+ ++ + + Y F+FD ++LLC K Q Y ++ A+ + YR+ P + +V + F+ + D+ W + I A+D ++P + H L MTTF+ + C CN++M GIF+QGY C RC +LH+ CI ++ S S S LP +N P + + + + ++ + V + EE+ + ++ WFAG ++ + A L+ P GTFLVR
Sbjct: 18 VLWREAVRWLVDLEMIPSDHRV--TWPDARVENLAYTLRDGVVLCNLALKLHPGCMDHKDMSLRPQMSQ-------FLCNKNIRAFLQALTNTFGITSPMDLFEPEMLFEYTDFKQVLHSLSVLSNSPEATKFGVKGFTA-----PKSVGNSE--YYNQSVFLKD--TPHNGTSFDTNGLNGHGPKHPRVTEEEEIYHKICVAPRSAPKPKTSERVIMIPILQVPLEKRDLCIQELLETEKNYIQALQMIRKKFQQPLEQAMSRDDAGVIFKHIRTLSDVHTGLLADLHVANQVPNGRISECFLRWKNSLI--IYGEYCSNYPRAQQLLQELLAKNDAVAQAIDKCQRETNDGRYQLNTLLCVPIQRVLKYHLLLKELVKNTLPQHDDYLGLEKALDAMLDLSAYINEVKRDSEMLQIIADIQNSITDYNLPKNVNLRDYGRLLKDGEVKVKSHKDQGVKNRYVFVFDQMLLLCKATKGDQ--YVYKEAISLSTYRVEDCQPMSGAASSSNSALVNAKSWQFQFLLVHLDQKTAYTIATKTLDDKLKWMEGIQKALDNLDPPAARQTDHERLDMTTFQAPSYCSHCNKLMKGIFYQGYSCSRCNKILHRDCIQHSKVCQIQSAAS--------------STPLPLSLNSPTIAVARNVIDVTRKVSVVLWEGRLGHNVGFFPAQYVEEIGQMNLDEHPWFAGTMSRERAEATLEPCPQGTFLVR 705
BLAST of EMLSAG00000000123 vs. nr
Match: gi|1101353468|ref|XP_018902786.1| (PREDICTED: protein vav isoform X2 [Bemisia tabaci]) HSP 1 Score: 223.402 bits (568), Expect = 3.111e-59 Identity = 197/701 (28.10%), Postives = 305/701 (43.51%), Query Frame = 0
Query: 26 LWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKS--KRDLPINELIDTEDKYLENLIMVRDVF-RDQLTLLSSKDKELIFYKLDELIRLHTEILTGLNIKGS-----QVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK------------------------NSEMIIDIVIH---------CLGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGEL--TAENSYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRI---GQTSPSHPNSIPLFHRIVPHPTPHLLFV--CRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGSTNSNASSINNNGLTKCDSVTLPTVINEPLERSESTLSLSPDSKQPSADRVSKLQRETEEELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVRKR 678
+W+EC +WL V+ P HK + P + + D +RDGVLLC L+ SLDP +DM V +Q F+C NI +FL A ++Y + FEP L+ + VI TLS LS+C K ++ ++PGF H + + ++E+IY ++ D +Y DT + E IYQ +C+ Q+ + + S + KRD INEL++TE Y++ L ++ F R +L D +IF+ + EL +H L+ L + ++ E FL +YGDYC +L + D I + + + CQ +A F L L +P QR LK E +ID+ + L + ++ +I L +L DFGRL K GEL A N ++ Y F+FD +IL+C K Q Y F+ ++ +RDY+I G H S +H + + R ++ W KAI DA D +EP H +M TF+ T+C C++ + GI +QGYRC +C HK+C I+ G LP PL S+ ++ P + P S ++ + + + WF G + +TA L+ GTFL+R R
Sbjct: 5 VWRECASWLTRCGVLRPDHKA-KWP-EADIFDLALTLRDGVLLCNLISSLDPGCIDMKDVNQKPQLAQ-------FLCLRNIKVFLQA-CHDYYGLPESDLFEPLMLFDFTDFYRVIHTLSKLSNCPKFQKKNIPGF---SVHRPRTL-SQEDIYRNLNST-EDVSPRGAIGGEQYSMY-DTHAHNEEIYQDLCSIDKQKATNGTHVPTPISHNLEKRDYVINELVETEKNYVDVLGTLQKCFIRPLQNVLKDDDFRVIFWGIKELAEIHGGFLSQLRKATTPNSMIKLSETFLNWREKFL-IYGDYCANLTTAQDKIQEICNRSENINQLIQVCQEEANNNKFKLRDILSVPMQRILKYHLLLDKLISETQPNHEDYRGLERAKEAMIDVAQYINEVKKDSDTLQIMADIQASITDWSLAENMELRDFGRLIKDGELRIKAHNDQKVKVR-YVFIFDQVILMCKALKGDQ--YCFKESLMLRDYKIEDAGSKRILHRESRWNYHWFLLRKGERFAYTMYARTEELKKKWIKAIQDAFDNIEPSACRNTDHKFSMHTFERPTTCSHCSKFLKGIIYQGYRCDKCYLAAHKQC------------------ISFTGRCGLKPPQLPARHASPL--SDPLVAELPQAVPPLPSDWSWSPAQSSDHGLTDYL----WFVGSMGRETAERLLEWQMDGTFLLRIR 661
BLAST of EMLSAG00000000123 vs. nr
Match: gi|919059920|ref|XP_013411704.1| (PREDICTED: proto-oncogene vav-like isoform X5 [Lingula anatina]) HSP 1 Score: 224.172 bits (570), Expect = 6.238e-59 Identity = 166/599 (27.71%), Postives = 283/599 (47.25%), Query Frame = 0
Query: 26 LWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICA------PKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQL-TLLSSKDKELIFYKLDELIRLHTEILTGLN-----IKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNS------------------------EMIIDIVIHC---------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARL-SDYAFLFDTIILLC---TRPKWL-QHRYRFRTAVKIRDYRIGQTSPS-HPNSIPLFHRIVPHPTPHLL---FVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCI 570
LW+ C WL +++P H+++ N+++ D +RDGVLLC L+++L P +VDM SQ F+C NI FL + F L + F+ DL+ ++ V+ TLS LS S + GFP L++ E++Y ++++ + E IY + ++ + IY+ +C+ + + + + K+KR+ + ELI+TE Y+E L M++ F L ++ S + ELIF ++ L +HT + L+ +G+ F++ P + LYGD+C +LP++ + I L +++ +R + CQ KA F L L +P QR LK E + D+ ++ L I ++ +I +Q+P L D+GRL K GEL ++ RL + Y FLFD ++L+C T K+L Y ++ A+ + +R+ + P+ P S H + + + F + + W AI A+D P E+GH MTTF+E +C C +++ G+F+QGY C RC+ +HK+CI
Sbjct: 6 LWRLCADWLIRCEILPRDHRVMFP--NAEIFDLAQTLRDGVLLCHLLNTLSPGAVDMKDFSQRPQMSQ-------FLCLKNIRTFLQTCKNKFGLRESD-LFDSYDLFDVKDFAKVLNTLSKLSKSELALASGIEGFPPD--RLSRVPSPVEDVYRTLEDRACELPDEDIYSAVTT-----VEEGEQEIYEDLCSLRGRTTRRRKERERDQLEQGFEPKTKREHCLKELIETEKNYVEALQMIKTFFIHPLKNIIPSPNHELIFKHIEGLGNIHTAFQSDLHQAVRRSSAQALGDCFIKYKPQLL-LYGDFCSNLPQAQERIDDLCRKNEIIRVAVEECQRKANEGKFRLRDLLSVPVQRVLKYHLLLKELIKQTDKKSPDRTFLEKALEAMQDLSLYVNEVKRDNEQLQLIQEIQDSIVDLQMPEKTSLKDYGRLLKDGELKIKSHEDNRLKTRYIFLFDKVMLMCKSRTMEKFLWGETYSYKNALVLAQHRVEEGVPAGRPRSEKWGHVFLLSENKNSVAYNFYAKTEEMKMKWVDAIKMALDNTNPANAREKGHDFIMTTFEEPQTCSECKKLLRGVFYQGYNCHRCKQSVHKECI 586
BLAST of EMLSAG00000000123 vs. nr
Match: gi|939246093|ref|XP_014242445.1| (PREDICTED: protein vav isoform X1 [Cimex lectularius]) HSP 1 Score: 221.861 bits (564), Expect = 9.283e-59 Identity = 191/716 (26.68%), Postives = 329/716 (45.95%), Query Frame = 0
Query: 26 LWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTIC-----------APKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENL-IMVRDVFRDQLTLLSSKDKELIFYKLDELIRLHTEILTGLNIK---------GSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK------------------------NSEMIIDIVIHCLGKIDVVEKTIKLMQ---------LPRGAQLSDFGRLRKAGELTAENSYGARLS-DYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTS---PSHPNSIPLFHRIV---PHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGSTNSNASSINNNGLTKCDSVTLPTVINEPLERSESTLSLSPDSKQPSADRVSKLQRETEE--ELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVRKR 678
LW++CV+WL V+ P H+ P ++ L+D +RDGVLLC +H+L+P+S++M V SQ F+C NI F++A +F + + FEP L+ ++ VI TLS LS+ K++R ++ GF + + ++E+IY ++ G+ + S + + DTQ E IYQ +C AP T S E KRD INEL++TE Y++ L +++ R +++ D + IF + EL +H G +I+ G ++ E FL +YG+YC +L ++ I + + + + +L CQ +A F L L +P QR LK E ++D+ + + ++ T+++M + +L++FGRL K G+L ++ + ++ Y F+FD +++LC K ++ +Y F+ + + D+++ S H ++ +H + T + L+ R + W KAI DA+D +EP H +M TF + T+C C++ + GI FQGY+C++C HK CI N G +C S P + P ++ E LS+ P + ++D + R + EL+ WF G++ + AS L+S GT+L+R R
Sbjct: 5 LWRDCVSWLTRCGVLRPDHRA-NWP-DATLTDLAYTLRDGVLLCNFLHNLEPASIEMKDVNQKPQFSQ-------FLCLRNIKTFINACHYHFGMKESD-LFEPSMLFELTDLYRVIHTLSKLSNSPKLQRHNIEGFSIHKP----RTLSQEDIYRNLNSSGGEEGACAVDKSCVEFAHYDTQIRNEEIYQDLCCIDKHSTPVIYAPTTINHSFE----------KRDYVINELVETEKNYIDVLNTLLKHFIRPLTSIIKDDDMKTIFGGIKELYEIHM----GFHIQLLKAVTPGSGFKLSEAFLNWREQFL-VYGEYCANLTKAQSRIVEISRNEI-VNQKLIKCQQEANNGKFKLRDILSVPMQRILKYHLLLEKLISETQPNHEDFRGLERAREAMVDVAQY-INEVKRDSDTLQIMADIEESITDWESKQTKLTNFGRLLKDGDLRIKDHHIQKIKPRYVFIFDRVMILC---KAVRDQYSFKACLSLADFKVEDASCRKTLHRDARWNYHWYLVRKSESTAYTLYA-RTEDLKRKWIKAIQDALDNIEPAGCRSTDHNFSMHTFDKPTTCTHCSKFLKGIIFQGYKCEKCNLAAHKMCIV------------------NTG--RCGSRQPPELPPRP-DKPEQELSVHPIVPKSTSDVFPESCRTWTDHGELVEY-----LWFVGEMGREKASRLLESQVDGTYLLRIR 659
BLAST of EMLSAG00000000123 vs. nr
Match: gi|919059917|ref|XP_013411703.1| (PREDICTED: proto-oncogene vav-like isoform X4 [Lingula anatina]) HSP 1 Score: 221.09 bits (562), Expect = 8.991e-58 Identity = 167/616 (27.11%), Postives = 286/616 (46.43%), Query Frame = 0
Query: 26 LWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGD----------AETEYIYDSFA--------KDIYN---DTQDNYENIYQTICA------PKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQL-TLLSSKDKELIFYKLDELIRLHTEILTGLN-----IKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNS------------------------EMIIDIVIHC---------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARL-SDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPS-HPNSIPLFHRIVPHPTPHLL---FVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCI 570
LW+ C WL +++P H+++ N+++ D +RDGVLLC L+++L P +VDM SQ F+C NI FL + F L + F+ DL+ ++ V+ TLS LS S + GFP+ I+ E + Y++++E+ + E +Y + +DIY+ ++ + IY+ +C+ + + + + K+KR+ + ELI+TE Y+E L M++ F L ++ S + ELIF ++ L +HT + L+ +G+ F++ P + LYGD+C +LP++ + I L +++ +R + CQ KA F L L +P QR LK E + D+ ++ L I ++ +I +Q+P L D+GRL K GEL ++ RL + Y FLFD ++L+C K Y ++ A+ + +R+ + P+ P S H + + + F + + W AI A+D P E+GH MTTF+E +C C +++ G+F+QGY C RC+ +HK+CI
Sbjct: 6 LWRLCADWLIRCEILPRDHRVMFP--NAEIFDLAQTLRDGVLLCHLLNTLSPGAVDMKDFSQRPQMSQ-------FLCLKNIRTFLQTCKNKFGLRESD-LFDSYDLFDVKDFAKVLNTLSKLSKSELALASGIDGFPQDNS----SIQVEHDYYNTLEELATGFPPDRLSRVPSPVEDVYRTLEDRACELPDEDIYSAVTTVEEGEQEIYEDLCSLRGRTTRRRKERERDQLEQGFEPKTKREHCLKELIETEKNYVEALQMIKTFFIHPLKNIIPSPNHELIFKHIEGLGNIHTAFQSDLHQAVRRSSAQALGDCFIKYKPQLL-LYGDFCSNLPQAQERIDDLCRKNEIIRVAVEECQRKANEGKFRLRDLLSVPVQRVLKYHLLLKELIKQTDKKSPDRTFLEKALEAMQDLSLYVNEVKRDNEQLQLIQEIQDSIVDLQMPEKTSLKDYGRLLKDGELKIKSHEDNRLKTRYIFLFDKVMLMC---KSRGETYSYKNALVLAQHRVEEGVPAGRPRSEKWGHVFLLSENKNSVAYNFYAKTEEMKMKWVDAIKMALDNTNPANAREKGHDFIMTTFEEPQTCSECKKLLRGVFYQGYNCHRCKQSVHKECI 603
BLAST of EMLSAG00000000123 vs. nr
Match: gi|919059913|ref|XP_013411701.1| (PREDICTED: proto-oncogene vav-like isoform X2 [Lingula anatina]) HSP 1 Score: 221.09 bits (562), Expect = 9.984e-58 Identity = 169/620 (27.26%), Postives = 289/620 (46.61%), Query Frame = 0
Query: 26 LWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGD----------AETEYIYDSFA--------KDIYN---DTQDNYENIYQTICA------PKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQL-TLLSSKDKELIFYKLDELIRLHTEILTGLN-----IKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNS------------------------EMIIDIVIHC---------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARL-SDYAFLFDTIILLC---TRPKWL-QHRYRFRTAVKIRDYRIGQTSPS-HPNSIPLFHRIVPHPTPHLL---FVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCI 570
LW+ C WL +++P H+++ N+++ D +RDGVLLC L+++L P +VDM SQ F+C NI FL + F L + F+ DL+ ++ V+ TLS LS S + GFP+ I+ E + Y++++E+ + E +Y + +DIY+ ++ + IY+ +C+ + + + + K+KR+ + ELI+TE Y+E L M++ F L ++ S + ELIF ++ L +HT + L+ +G+ F++ P + LYGD+C +LP++ + I L +++ +R + CQ KA F L L +P QR LK E + D+ ++ L I ++ +I +Q+P L D+GRL K GEL ++ RL + Y FLFD ++L+C T K+L Y ++ A+ + +R+ + P+ P S H + + + F + + W AI A+D P E+GH MTTF+E +C C +++ G+F+QGY C RC+ +HK+CI
Sbjct: 6 LWRLCADWLIRCEILPRDHRVMFP--NAEIFDLAQTLRDGVLLCHLLNTLSPGAVDMKDFSQRPQMSQ-------FLCLKNIRTFLQTCKNKFGLRESD-LFDSYDLFDVKDFAKVLNTLSKLSKSELALASGIDGFPQDNS----SIQVEHDYYNTLEELATGFPPDRLSRVPSPVEDVYRTLEDRACELPDEDIYSAVTTVEEGEQEIYEDLCSLRGRTTRRRKERERDQLEQGFEPKTKREHCLKELIETEKNYVEALQMIKTFFIHPLKNIIPSPNHELIFKHIEGLGNIHTAFQSDLHQAVRRSSAQALGDCFIKYKPQLL-LYGDFCSNLPQAQERIDDLCRKNEIIRVAVEECQRKANEGKFRLRDLLSVPVQRVLKYHLLLKELIKQTDKKSPDRTFLEKALEAMQDLSLYVNEVKRDNEQLQLIQEIQDSIVDLQMPEKTSLKDYGRLLKDGELKIKSHEDNRLKTRYIFLFDKVMLMCKSRTMEKFLWGETYSYKNALVLAQHRVEEGVPAGRPRSEKWGHVFLLSENKNSVAYNFYAKTEEMKMKWVDAIKMALDNTNPANAREKGHDFIMTTFEEPQTCSECKKLLRGVFYQGYNCHRCKQSVHKECI 610
BLAST of EMLSAG00000000123 vs. nr
Match: gi|919059915|ref|XP_013411702.1| (PREDICTED: protein vav-like isoform X3 [Lingula anatina]) HSP 1 Score: 220.705 bits (561), Expect = 1.071e-57 Identity = 169/620 (27.26%), Postives = 289/620 (46.61%), Query Frame = 0
Query: 26 LWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGD----------AETEYIYDSFA--------KDIYN---DTQDNYENIYQTICA------PKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQL-TLLSSKDKELIFYKLDELIRLHTEILTGLN-----IKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNS------------------------EMIIDIVIHC---------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARL-SDYAFLFDTIILLC---TRPKWL-QHRYRFRTAVKIRDYRIGQTSPS-HPNSIPLFHRIVPHPTPHLL---FVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCI 570
LW+ C WL +++P H+++ N+++ D +RDGVLLC L+++L P +VDM SQ F+C NI FL + F L + F+ DL+ ++ V+ TLS LS S + GFP+ I+ E + Y++++E+ + E +Y + +DIY+ ++ + IY+ +C+ + + + + K+KR+ + ELI+TE Y+E L M++ F L ++ S + ELIF ++ L +HT + L+ +G+ F++ P + LYGD+C +LP++ + I L +++ +R + CQ KA F L L +P QR LK E + D+ ++ L I ++ +I +Q+P L D+GRL K GEL ++ RL + Y FLFD ++L+C T K+L Y ++ A+ + +R+ + P+ P S H + + + F + + W AI A+D P E+GH MTTF+E +C C +++ G+F+QGY C RC+ +HK+CI
Sbjct: 6 LWRLCADWLIRCEILPRDHRVMFP--NAEIFDLAQTLRDGVLLCHLLNTLSPGAVDMKDFSQRPQMSQ-------FLCLKNIRTFLQTCKNKFGLRESD-LFDSYDLFDVKDFAKVLNTLSKLSKSELALASGIDGFPQDNS----SIQVEHDYYNTLEELATGFPPDRLSRVPSPVEDVYRTLEDRACELPDEDIYSAVTTVEEGEQEIYEDLCSLRGRTTRRRKERERDQLEQGFEPKTKREHCLKELIETEKNYVEALQMIKTFFIHPLKNIIPSPNHELIFKHIEGLGNIHTAFQSDLHQAVRRSSAQALGDCFIKYKPQLL-LYGDFCSNLPQAQERIDDLCRKNEIIRVAVEECQRKANEGKFRLRDLLSVPVQRVLKYHLLLKELIKQTDKKSPDRTFLEKALEAMQDLSLYVNEVKRDNEQLQLIQEIQDSIVDLQMPEKTSLKDYGRLLKDGELKIKSHEDNRLKTRYIFLFDKVMLMCKSRTMEKFLWGETYSYKNALVLAQHRVEEGVPAGRPRSEKWGHVFLLSENKNSVAYNFYAKTEEMKMKWVDAIKMALDNTNPANAREKGHDFIMTTFEEPQTCSECKKLLRGVFYQGYNCHRCKQSVHKECI 610
BLAST of EMLSAG00000000123 vs. nr
Match: gi|919059910|ref|XP_013411700.1| (PREDICTED: proto-oncogene vav-like isoform X1 [Lingula anatina]) HSP 1 Score: 220.705 bits (561), Expect = 1.224e-57 Identity = 169/620 (27.26%), Postives = 289/620 (46.61%), Query Frame = 0
Query: 26 LWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGD----------AETEYIYDSFA--------KDIYN---DTQDNYENIYQTICA------PKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQL-TLLSSKDKELIFYKLDELIRLHTEILTGLN-----IKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNS------------------------EMIIDIVIHC---------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARL-SDYAFLFDTIILLC---TRPKWL-QHRYRFRTAVKIRDYRIGQTSPS-HPNSIPLFHRIVPHPTPHLL---FVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCI 570
LW+ C WL +++P H+++ N+++ D +RDGVLLC L+++L P +VDM SQ F+C NI FL + F L + F+ DL+ ++ V+ TLS LS S + GFP+ I+ E + Y++++E+ + E +Y + +DIY+ ++ + IY+ +C+ + + + + K+KR+ + ELI+TE Y+E L M++ F L ++ S + ELIF ++ L +HT + L+ +G+ F++ P + LYGD+C +LP++ + I L +++ +R + CQ KA F L L +P QR LK E + D+ ++ L I ++ +I +Q+P L D+GRL K GEL ++ RL + Y FLFD ++L+C T K+L Y ++ A+ + +R+ + P+ P S H + + + F + + W AI A+D P E+GH MTTF+E +C C +++ G+F+QGY C RC+ +HK+CI
Sbjct: 6 LWRLCADWLIRCEILPRDHRVMFP--NAEIFDLAQTLRDGVLLCHLLNTLSPGAVDMKDFSQRPQMSQ-------FLCLKNIRTFLQTCKNKFGLRESD-LFDSYDLFDVKDFAKVLNTLSKLSKSELALASGIDGFPQDNS----SIQVEHDYYNTLEELATGFPPDRLSRVPSPVEDVYRTLEDRACELPDEDIYSAVTTVEEGEQEIYEDLCSLRGRTTRRRKERERDQLEQGFEPKTKREHCLKELIETEKNYVEALQMIKTFFIHPLKNIIPSPNHELIFKHIEGLGNIHTAFQSDLHQAVRRSSAQALGDCFIKYKPQLL-LYGDFCSNLPQAQERIDDLCRKNEIIRVAVEECQRKANEGKFRLRDLLSVPVQRVLKYHLLLKELIKQTDKKSPDRTFLEKALEAMQDLSLYVNEVKRDNEQLQLIQEIQDSIVDLQMPEKTSLKDYGRLLKDGELKIKSHEDNRLKTRYIFLFDKVMLMCKSRTMEKFLWGETYSYKNALVLAQHRVEEGVPAGRPRSEKWGHVFLLSENKNSVAYNFYAKTEEMKMKWVDAIKMALDNTNPANAREKGHDFIMTTFEEPQTCSECKKLLRGVFYQGYNCHRCKQSVHKECI 610
BLAST of EMLSAG00000000123 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold693_size110418-snap-gene-0.23 (protein:Tk06977 transcript:maker-scaffold693_size110418-snap-gene-0.23-mRNA-1 annotation:"hypothetical protein YQE_10749 partial") HSP 1 Score: 97.0561 bits (240), Expect = 4.861e-21 Identity = 63/201 (31.34%), Postives = 100/201 (49.75%), Query Frame = 0
Query: 26 LWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEI----------YGDAETEYIYDSFAKDIYNDTQDNYENIYQ 216
LWK+C WL ++P H++ T ++K+ D +RDGVLLC + +LD SS+D+ +Q F+C NI LFL + + F L + F P LY + V+ TLS LS+C K K V GFP++ K + ++EE IY +++++ Y E Y + Y++ Q + E+IY+
Sbjct: 169 LWKQCADWLCRMDILPNNHRI--TWPDAKIQDLAYTLRDGVLLCHIAKALDESSLDLHSAHLRPQMAQ-------FLCLKNIRLFLQSCLDKFGLEETD-LFHPTMLYDYSDFARVLHTLSKLSNCAKAKAKEVNGFPQQYKEPS---QDEEQIYRTLEDMVNEDNYKAFYYDHHGAESAYGKMNRPYYSEGQKD-EDIYE 355 HSP 2 Score: 78.5666 bits (192), Expect = 2.891e-15 Identity = 53/202 (26.24%), Postives = 90/202 (44.55%), Query Frame = 0
Query: 305 QVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHC---------------------------------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAE--NSYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQ 471
++GEIF+ + YGDYC LP++ + + L + +R ++ C+ A F L L +P QR LK ++ +++ + LG I+ +E +I LP G L D+GRL GEL + ++ G + F+FD IIL+C + Y ++ ++K+ DYR+ Q
Sbjct: 359 KIGEIFIEYKKRFLK-YGDYCSDLPKAQEALDALLNKAENVRDEITQCEQNANEGKFRLRDLLAVPMQRILKYHLLLRELLSNTPSTHEEHHTLKQAYEAMLDVSDFINEVKRDSEQLGIINEIESSITDWNLPEGVCLKDYGRLLSDGELKVQSHDTNGKTKLRFVFVFDKIILMCKATR--GDHYAYKNSLKLSDYRVEQ 557 The following BLAST results are available for this feature:
BLAST of EMLSAG00000000123 vs. GO
Analysis Date: 2014-04-02 (Blast vs. GO) Total hits: 25
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BLAST of EMLSAG00000000123 vs. C. finmarchicus
Analysis Date: 2014-05-09 (TblastN vs C. finmarchicus TSA) Total hits: 25
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BLAST of EMLSAG00000000123 vs. L. salmonis peptides
Analysis Date: 2014-05-10 (Blastp vs. self) Total hits: 3
BLAST of EMLSAG00000000123 vs. SwissProt
Analysis Date: 2017-02-10 (Blastp vs. SwissProt) Total hits: 13
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BLAST of EMLSAG00000000123 vs. Select Arthropod Genomes
Analysis Date: 2017-02-20 (Blastp vs. Selected Arthropods) Total hits: 23
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BLAST of EMLSAG00000000123 vs. nr
Analysis Date: 2017-02-20 (Blastp vs. NR (2/2017)) Total hits: 25
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BLAST of EMLSAG00000000123 vs. Tigriopus kingsejongenis genes
Analysis Date: 2018-04-18 (Blastp vs. Tigriopus kingsejongensis proteins) Total hits: 1
Alignments
The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Cross References
External references for this gene
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at LSalAtl2s101:528275..535129- Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>EMLSAG00000000123-682889 ID=EMLSAG00000000123-682889|Name=EMLSAG00000000123|organism=Lepeophtheirus salmonis|type=gene|length=6855bp|location=Sequence derived from alignment at LSalAtl2s101:528275..535129- (Lepeophtheirus salmonis)back to top Add to Basket
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