Query:   38 PIDESRKGLSIFGFVRFQNTACNGTTR-NGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYLSKGSDSTS----DCSFTICPKHSNICRIRFDFIVFRISDPVSSITNV--GGSIGDCTTDSFSITGENGGSP-VICGTNSGRHMIVDSIATCNMAQXX--XXXXXXXXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPTV--TGTMSKDSYGLGPSSNGIEAKSLVNEKCK-----------GDFLEILSGIPFTSTNQMTVGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQF 403
            P + S K LS+F  + F NT C  ++  NGTCYTS+EC + GG  +G TCAS +      +L CG +SS+N TY    S STS     C +TIC  +S +C++R DF    ++ P ++ T    G  +GDC  D+ +IT   G SP +ICG N+G+HM V +   CN        G      ++ IKVTQFECG     +A    CLQY T Q+G I  + + TS +   +     HLSSQ+Y +CIRR  G C +CY P V  T T +  SYG+G  +        V   C            GD+LEI +  P   T+  T     +ICG  FN A   I   + CSF++PF++    D++E         +N+ + +P  T G    Y  F
Sbjct:    6 PEERSSKQLSMFNVITFPNTVCASSSGFNGTCYTSSECLSLGGSASG-TCASSFGVCCVFSLGCGSSSSQNNTYFIISSFSTSADADPCQYTICKSNSAVCKLRIDFDSMVLAPPYTTTTTADDGIRVGDCLYDTLTITNPGGSSPPIICGYNTGQHMFVPASDGCNALNIDIDTGTTTTTRSWQIKVTQFECG---DMMAPDQDCLQYHTSQTGTIATFNWDTSTT--TVASTQLHLSSQNYNVCIRRARGQCSVCYSPEVTSTTTGTAASYGVGAGTIAAIQTGSVGAICTGITTQPGTLGYGDYLEIANLQPTIGTSGTTT-TGTRICGVIFN-AIANIAHATACSFAIPFKVGVHFDEEESILAATANNLNKAENDPLATAGAGYGYSGF 1163          

Query:   39 IDESR--KGLSIFGFVRFQNTACNGTT-RNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTY-----LSKGSDSTSDCSFTICPKHSNICRIRFDFIVFRISDP--VSSITNV--GGSIGDCTTDSFSITGENGGSP-VICGTNSGRHMIVDSIATCNMAQXX--XXXXXXXXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIP---TVTGTMSKDSYGLGPSSNGIEAKSLVNEKCK---------------GDFLEI-LSGIPFTSTNQMTVGAVNKICGRYFNTADDQIVSIS-VCSFSLPFELRFVTDQDE---MTPETGDAVMNENKEEPRGTV-------GFSLTYKQFPC 405
            ID+S+  K LS+F  V F N+AC  T+  NGTCYT++EC+   G  +G TCAS +      ++ CG +SS+N +Y      S  SDS   C++T C  +S++C++R DF    ++DP  +SS      G  +GDC TD+ +++   G +P +ICGTN+G+HM V +   CN        G       + IK++QF+CG     ++    CLQY T Q+G I ++ +   IS   +     HLS+QDY ICIRR    C ICY P   ++T  ++        S    +  S+    C                GDFLEI  S  P T+    TV A ++ICG  +N A     + S VCSF  PF++    D+DE     P T  A +++ + +P  T        GF LTY Q  C
Sbjct:  163 IDDSKQAKALSVFNIVSFPNSACGATSGYNGTCYTASECTALSGTASG-TCASSFGVCCVFSIACGASSSQNNSYAIITSYSVSSDS-DPCTYTFCKANSDVCKLRIDFDTMVLADPEGISSTAAYTDGPKVGDCATDTLTVSNPGGSAPPIICGTNTGQHMFVPASDNCNKINIDIDTGSTGTTRKWQIKISQFKCG---DAMSPGQDCLQYHTAQTGTIASFNW--DISSTTVSTSQYHLSNQDYNICIRRARKKCEICYTPKIYSITTGIASSYGVGSSSVAATQTASISVATCTGVTTQATSTSTGLGVGDFLEIGNSQAPPTTAG--TVNANSRICGVLWNVASIAGTTQSTVCSFVKPFKILVHFDEDEAIHANPGTATANLDKGENDPLATTGAGYGYSGFWLTYFQNEC 1386          

Query:   38 PIDESRKGLSIFGFVRFQNTACNGTT-RNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYLSKGSDSTSD----CSFTICPKHSNICRIRFDFIVFRISDPVSSITNV--GGSIGDCTTDSFSITGENGGSP-VICGTNSGRHMIVDSIATCNMAQXXXXXXXXXXA--FDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPTVTGTMSK--DSYGLGPSSNGIEAKSLVNEKCK-----------GDFLEILSGIPFTSTNQMTVGAVNKICGRYFNTAD-DQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTV------------GFSLTYKQFPC 405
            P     K LS+F  V F N AC  +T  NGTCYT++EC+++GG  +G TCAS +       L CG ++++N TY    S STS     CS+T+C +++++C++R DF +  +++P S+ T    G  +GDC  D+ +++   G SP +ICG N+G+HM V + A CN        G       + IKVTQFECG +   +A    CLQYFT Q+G I  + + T+     +     HLS+Q Y IC RR    C +C  P ++ T++K   SYGL   S     KS     C            GD++EI +  P   T      A +++CG  F+ A    I   + C+++ PF++    D+ E    +  A    N  E  G+             GF L Y    C
Sbjct:  222 PNARDGKALSVFNVVTFPNVACGASTGYNGTCYTASECTSKGGTASG-TCASSFGVCCVFNLACGASTTQNNTYAIISSYSTSSDADPCSYTVCKQNADVCKLRIDFDIMVLANPYSTTTAAADGPKVGDCFYDTLTVSNPGGTSPPIICGYNTGQHMFVPASAACNTINIDVDTGTTTTTRKWQIKVTQFECGNQ---MAPEMDCLQYFTAQTGTIATFNWDTT--STTVASTQVHLSNQYYDICFRRVRSYCSLCLSPQISSTIAKIASSYGLSTGSTEATVKSAFGTTCTGVTTQPAKAAYGDYIEIANLQPSIGTTGTITTA-SRLCGTVFSAASIATIAGATACTWAKPFKIGVHFDEGESLVSSEQAAKKFNLGENIGSTNIAAGGDGYGYSGFWLAYWMNAC 1427          

Query:   40 DESR--KGLSIFGFVRFQNTACNGTT-RNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYLSKGSDSTS----DCSFTICPKHSNICRIRFDFIVFRISDP--VSSITNV--GGSIGDCTTDSFSITGENGGSP-VICGTNSGRHMIVDSIATCNMAQXXXXXXXXXXA--FDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPTVTGTMS--KDSYGLGPSSNGIEAKSLVNEKCK-----------GDFLEILSGIPFTSTNQMTVGAVN---KICGRYFNT-ADDQIVSISVCSFSLPFELRFVTDQDE--MTPETGDAVMNENKEE--PRGT-------VGFSLTYKQFPC 405
            D +R  K LS+F  V F N+AC  T+  NGTCYT+ ECS+ GG  +G TCAS +      +++CG +SS N TY    S STS     C++T C  +S++C++R DF    ++ P  VS++ NV  G   G C  DS ++T   G SP +ICG N+G+HM + +  +CN        G       + IKVTQ+ECG  ++ + G   CLQY T  SG I  + + TS S  V  G+  HL++Q Y ICIRR    C +CY P ++ +++    SYG+G SS G + ++ +   C            GD+LEI +  P TS      G VN   +ICG  FNT A  Q    + CS ++PF++    D +E  +    G A  N NK E  P  T        GF L+Y Q  C
Sbjct:  138 DRTRQAKALSVFNVVSFPNSACGATSGYNGTCYTAAECSSLGGTASG-TCASSFGVCCVFSISCGSSSSSNNTYAIISSYSTSTDADPCTYTFCKTNSDVCKLRIDFDTMVLAAPYTVSTVANVDHGVRTGHCGYDSLTVTNPGGQSPPIICGYNTGQHMWIPASDSCNAINIDVDTGTTTTTRKWQIKVTQYECG--NSMMPG-QDCLQYHTAASGSIATFNWDTS-STTVSSGQ-VHLANQAYDICIRRTRSYCSVCYTPYISSSITGIASSYGVGASSTGPKQQAAIATLCTGITTQPAALGFGDYLEIANLQPATSAIASIAGTVNANSRICGAIFNTAASPQTAGATACSHAIPFKVGVHFDDEESFLAGPAGAASPNMNKAENDPAATDGAGYGYSGFWLSYWQNAC 1358          

Query:   41 ESRKGLSIFGFVRFQNTACNGTT-RNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYLSKGSDSTS----DCSFTICPKHSNICRIRFDFIVFRISDP--VSSITNV--GGSIGDCTTDSFSITGENGGSP-VICGTNSGRHMIVDSIATCNMAQXXXXXXXXXXA--FDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPTVTGTMS--KDSYGLGPSSNGIEAKSLVNEKCK-----------GDFLEILSGIPFTSTNQMTVGAVN---KICGRYFNT-ADDQIVSISVCSFSLPFELRFVTDQDE--MTPETGDAVMNENKEE--PRGT-------VGFSLTYKQFPC 405
            +  K LSIF  V F N+AC  T+  NGTCYT+ ECS+ GG  +G TCAS +      +++CG +SS N TY    S STS     C++T C  +S++C++R DF    ++ P  VS++ NV  G   G C  DS ++T   G SP +ICG N+G+HM + +  +CN        G       + IKVTQ+ECG  ++ + G   CLQY T  SG I  + + TS S  V  G+  HL++Q Y ICIRR    C +CY P ++ +++    SYG+G SS G + ++ +   C            GD+LEI +  P TS      G VN   +ICG  FNT A  Q    + CS ++PF++    D +E  +    G A  N NK E  P  T        GF L+Y Q  C
Sbjct:  234 KQAKALSIFNVVTFPNSACGATSGYNGTCYTAAECSSLGGTASG-TCASSFGVCCVFSISCGSSSSSNNTYAIISSYSTSTDADPCTYTFCKTNSDVCKLRIDFDTMVLAAPYTVSTVANVDHGVRTGHCGYDSLTVTNPGGQSPPIICGYNTGQHMWIPASDSCNAINIDVDTGTTTTTRKWQIKVTQYECG--NSMMPG-QDCLQYHTAASGSIATFNWDTS-STTVSSGQ-VHLANQAYDICIRRTRSYCSVCYTPYISSSITGIASSYGVGASSTGPKQQAAIATLCTGITTQPAALGFGDYLEIANLQPATSAIASIAGTVNANSRICGAIFNTAASPQTAGATACSHAIPFKVGVHFDDEESFLAGPAGAASPNMNKAENDPAATDGAGYGYSGFWLSYWQNAC 1445          

Query:   39 IDESR--KGLSIFGFVRFQNTACNGTT-RNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTY-----LSKGSDSTSDCSFTICPKHSNICRIRFDFIVFRISDP--VSSITNV--GGSIGDCTTDSFSITGENGGSP-VICGTNSGRHMIVDSIATCNMAQXX--XXXXXXXXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIP---TVTGTMSKDSYGLGPSSNGIEAKSLVNEKCK---------------GDFLEI-LSGIPFTSTNQMTVGAVNKICGRYFNTADDQIVSIS-VCSFSLPFELRFVTDQDE---MTPETGDAVMNENKEEPRGTV-------GFSLTYKQFPC 405
            +D+S+  K LS+F  V F N+AC  T+  NGTCYT++EC+   G  +G TCAS +      ++ CG +SS+N +Y      S  SDS   C++T C  +S++C++R DF    ++DP  +SS      G  +GDC TD+ +++   G +P +ICGTN+G+HM V +   CN        G       + IK++QF+CG     ++    CLQY T Q+G I ++ +   IS   +     HLS+QDY ICIRR    C ICY P   ++T  ++        S    +  S+    C                GDFLEI  S  P T+    TV A ++ICG  +N A     + S VCSF  PF++    D+DE     P T  A +++ + +P  T        GF LTY Q  C
Sbjct:  149 VDDSKQAKALSVFNIVSFPNSACGATSGYNGTCYTASECTALSGTASG-TCASSFGVCCVFSIACGASSSQNNSYAIITSYSVSSDS-DPCTYTFCKANSDVCKLRIDFDTMVLADPEGISSTAAYTDGPKVGDCATDTLTVSNPGGSAPPIICGTNTGQHMFVPASDNCNKINIDIDTGSTGTTRKWQIKISQFKCG---DAMSPGQDCLQYHTAQTGTIASFNW--DISSTTVSTSQYHLSNQDYNICIRRARKKCEICYTPKIYSITTGIASSYGVGSSSVAATQTASISVATCTGVTTQATSTSTGLGVGDFLEIGNSQAPPTTAG--TVNANSRICGVLWNVASIAGTTQSTVCSFVKPFKILVHFDEDEAIHANPGTATANLDKGENDPLATTGAGYGYSGFWLTYFQNEC 1372          

Query:   38 PIDESRKGLSIFGFVRFQNTACNGTT-RNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYLSKGSDSTSD----CSFTICPKHSNICRIRFDFIVFRISDPVSSITNV--GGSIGDCTTDSFSITGENGGSP-VICGTNSGRHMIVDSIATCNMAQXXXXXXXXXXA--FDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPTVTGTMSK--DSYGLGPSSNGIEAKSLVNEKCK-----------GDFLEILSGIPFTSTNQMTVGAVNKICGRYFNTAD-DQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTV------------GFSLTYKQFPC 405
            P     K LS+F  V F N AC  +T  NGTCYT++EC+++GG  +G TCAS +       L CG ++++N TY    S STS     CS+T+C +++++C++R DF +  +++P S+ +    G  +GDC  D+ +++   G SP +ICG N+G+HM V + A CN        G       + IKVTQFECG +   +A    CLQYFT Q+G I  + + T+     +     HLS+Q Y IC RR    C +C  P ++ T++K   SYGL   S     KS     C            GD++EI +  P   T      A +++CG  F+ A    I   + C+++ PF++    D+ E    +  A    N  E  G+             GF L Y    C
Sbjct:  134 PNARDGKALSVFNVVTFPNVACGASTGYNGTCYTASECTSKGGTASG-TCASSFGVCCVFNLACGASTTQNNTYAIISSYSTSSDADPCSYTVCKQNADVCKLRIDFDIMVLANPYSTTSAATDGPKVGDCFYDTLTVSNPGGTSPPIICGYNTGQHMFVPASAACNTINIDVDTGTTTTTRKWQIKVTQFECGNQ---MAPEMDCLQYFTAQTGTIATFNWDTT--STTVASTQVHLSNQYYDICFRRVRSYCSLCLSPQISSTIAKIASSYGLSTGSTEATVKSAFGTTCTGVTTQPAKAAYGDYIEIANLQPSIGTTGTITTA-SRLCGTVFSAASIATIAGATACTWAKPFKIGVHFDEGESLVSSEQAAKKFNLGENIGSTNIAAGGDGYGYSGFWLAYWMNAC 1339          

Query:   38 PIDESRKGLSIFGFVRFQNTACNGTT-RNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYLSKGSDSTSD----CSFTICPKHSNICRIRFDFIVFRISDPVSSITNV--GGSIGDCTTDSFSITGENGGSP-VICGTNSGRHMIVDSIATCNMAQXXXXXXXXXXA--FDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPTVTGTMSK--DSYGLGPSSNGIEAKSLVNEKCK-----------GDFLEILSGIPFTSTNQMTVGAVNKICGRYF 344
            P     K LS+F  V F N AC  +T  NGTCYT++EC+++GG  +G TCAS +       L CG ++++N TY    S STS     CS+T+C +++++C++R DF +  +++P S+ +    G  +GDC  D+ +++   G SP +ICG N+G+HM V + A CN        G       + IKVTQFECG +   +A    CLQYFT Q+G I  + + T+     +     HLS+Q Y IC RR    C +C  P ++ T++K   SYGL   S     KS     C            GD++EI +  P   T      A +++CG  F
Sbjct:  134 PNARDGKALSVFNVVTFPNVACGASTGYNGTCYTASECTSKGGTASG-TCASSFGVCCVFNLACGASTTQNNTYAIISSYSTSSDADPCSYTVCKQNADVCKLRIDFDIMVLANPYSTTSAATDGPKVGDCFYDTLTVSNPGGTSPPIICGYNTGQHMFVPASAACNTINIDVDTGTTTTTRKWQIKVTQFECGNQ---MAPEMDCLQYFTAQTGTIATFNWDTT--STTVASTQVHLSNQYYDICFRRVRSYCSLCLSPQISSTIAKIASSYGLSTGSTEATVKSAFGTTCTGVTTQPAKAAYGDYIEIANLQPSIGTTGTITTA-SRLCGTVF 1117          

Query:   40 DESRKGLSIFGFVRFQNTACNGTT--RNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGG-TSSENCTY-----LSKGSDSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSS-----ITNVGGS-IGDCTTDSFSITGENGGS-PVICGTNSGRHMIVDSIATCNM--AQXXXXXXXXXXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPTV------TGTMSKDSYGLGPSSNGIEAKSLVNEKCKGDFLEILSG---IPFTSTNQMTVGAVNKICGRYFNTA-------DDQIVSISVCSFSLPFELRFVTDQDEMT-PETG--DAVMNENKEEPRGTVGFSLTY 400
              + K LS+F  V+F NTAC  +T  RNGTCYTS+ECS +GG  +G +CAS +        TCGG +SSEN TY     LSKGS     C  TIC   S +C++R DF  F +++PV+S      T V  + IG C TDSFS+T   G S P ICGTN+G+HM + +   CN+  A        +  AF IKVTQ EC    +  A PSGC QYFTG +G IE Y +  +   L        L++QDY ICIR E   C ICY  T        G  +  S G+  ++ G     L+      D + I +G    P T       GA+     RY  TA          I + +VCS   PF++   +D  E   P      AV+  N       +GFS++Y
Sbjct:  163 QRAEKALSVFTVVKFPNTACASSTTGRNGTCYTSSECSAKGGTSSG-SCASSFGVCCIFEKTCGGGSSSENSTYFTSSALSKGSS----CGLTICKSDSTVCQLRLDFETFVLNNPVTSTVVTIATPVAANRIGSCDTDSFSVTVPGGKSPPAICGTNTGQHMYIPASDQCNVLNANIGSASTASTSAFTIKVTQVEC---TSKRAAPSGCTQYFTGSTGTIETYNYNAAAGVL--------LANQDYSICIRTERTYCSICYWSTSFKLSVPKGDAAIASLGV-DTNCGAAGNVLIANGGAFDHIVIPAGQCNTPATGA-PAAQGAIAVTADRYCGTALYCLGTAAATIATATVCSNQKPFKISLESDGLEYAFPAAAGEGAVVGNN-------IGFSISY 1293          

Query:   40 DESRKGLSIFGFVRFQNTACNGTT--RNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGG-TSSENCTY-----LSKGSDSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSS-----ITNVGGS-IGDCTTDSFSITGENGGS-PVICGTNSGRHMIVDSIATCNM--AQXXXXXXXXXXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPT 283
              + K LS+F  V+F NTAC  +T  RNGTCYTS+ECS +GG  +G +CAS +        TCGG +SSEN TY     LSKGS     C  TIC   S +C++R DF  F +++PV+S      T V  + IG C TDSFS+T   G S P ICGTN+G+HM + +   CN+  A        +  AF IKVTQ EC    +  A PSGC QYFTG +G IE Y +  +   L        L++QDY ICIR E   C ICY  T
Sbjct:  541 QRAEKALSVFTVVKFPNTACASSTTGRNGTCYTSSECSAKGGTSSG-SCASSFGVCCIFEKTCGGGSSSENSTYFTSSALSKGSS----CGLTICKSDSTVCQLRLDFETFVLNNPVTSTVVTIATPVAANRIGSCDTDSFSVTVPGGKSPPAICGTNTGQHMYIPASDQCNVLNANIGSASTASTSAFTIKVTQVEC---TSKRAAPSGCTQYFTGSTGTIETYNYNAAAGVL--------LANQDYSICIRTERTYCSICYWST 1290          

Query:    1 MVIFKFNQFKYITMERFSHLWKMLFLISFMAFACQCSPIDESRKGLSIFGFVRFQNTACNGTTRNGTCYTSNECSTRGGLPAGDTCASGYVTLTCGGTSSENCTYLSKGSDSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVDSIATCNMAQFFFGGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPTVTGTMSKDSYGLGPSSNGIEAKSLVNEKCKGDFLEILSGIPFTSTNQMTVGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
            MVIFKFNQFKYITMERFSHLWKMLFLISFMAFACQCSPIDESRKGLSIFGFVRFQNTACNGTTRNGTCYTSNECSTRGGLPAGDTCASGYVTLTCGGTSSENCTYLSKGSDSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVDSIATCNMAQFFFGGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPTVTGTMSKDSYGLGPSSNGIEAKSLVNEKCKGDFLEILSGIPFTSTNQMTVGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC
Sbjct:    1 MVIFKFNQFKYITMERFSHLWKMLFLISFMAFACQCSPIDESRKGLSIFGFVRFQNTACNGTTRNGTCYTSNECSTRGGLPAGDTCASGYVTLTCGGTSSENCTYLSKGSDSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVDSIATCNMAQFFFGGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPTVTGTMSKDSYGLGPSSNGIEAKSLVNEKCKGDFLEILSGIPFTSTNQMTVGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405          

Query:   37 SPIDESRKGLSIFGFVRFQNTACNGTTRNGTCYTSNECSTRGGLPAGDTCASGYVT-----LTCGGTSSENCTYLSKGSDSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVDSIATCNMAQFFFGGGFNNXA----FDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPTVTGTMSKDSYGLGPSSNGIEAKSLVNEKCKGDFLEILSGIPFTSTNQMTVGA--VNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
            SP + +R    IF  ++F+N  C   +  GTCYTS ECS+RGG  AG +CASGY T     L CGGT+SEN TYL   S  T+DC++TIC   +N+CRIR DF+ F I+ P  +  N   S G+C TDSF+++G  GGSPVICG N+G+HMIV++  TCN A  FF  G N       + I VTQ+ECG E     GP GCLQY T  SG ++++ + T  +       A HL+ QDY +C RR  GNCRICY  TV   +  +++GL  S++  +AKS  N  C  DF+EI +G+  T     T+ A  V + CGR+ NT  +   + +VCSFSLPF  RFVTD  E     G A + E K +P G +G+ + YKQ  C
Sbjct:   31 SPPNRARL---IFNIIKFENDPCGTGSMVGTCYTSEECSSRGGT-AGGSCASGYGTCCVFSLGCGGTTSENSTYLEVTS-RTTDCAYTICRCSTNVCRIRLDFLNFVINGPEMADDNPN-SYGNCNTDSFTVSGNQGGSPVICGFNTGQHMIVEAQDTCNTA--FFNIGDNTAGVTRTWSINVTQYECGDE---FGGPPGCLQYLTSTSGFVQSFNYNTRTT-------AVHLADQDYNVCFRRAPGNCRICY-ATVNEGVDIETFGLSISTDAAQAKSGTNTDCSTDFIEIPAGVRETDLTLATLPANTVFRNCGRFLNTKRNLKATTTVCSFSLPFRFRFVTDTTEAL-AAGGANVKETKLDPSGVIGYKMFYKQMAC 390          

Query:   41 ESRKG--LSIFGFVRFQNTACNGTTRNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYLSKGSDSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVDSIATCNMAQFFFG-GGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPTVTGTMSKDSYGLGPSSNGIEAKSLVNEKCKGDFLEILSGIPFTSTNQMTVGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
            +SR G  L +F  VRFQN  C      GTCYT  EC++RGG   G  CA GY      T  C   SSEN TYL+  + S   CS+ IC  +  +CR+RFDFI F ++ PV +    G SIGDCTTD FS+T  NGGSPVICGTN+G+H+IVD+   CN+A F  G   F+  +++++VTQ+ C  ++++  GP GCLQYFT  +GVI ++ FP++       G  THLS+Q Y  C RR T  C IC+ PT TG  + +S+G+  S+      S     C GD++ I        ++   +   N++CG   +T   + VS ++C+   PF + F TD DE T     +  NE K  P GTVGFSL+Y Q  C
Sbjct:   33 QSRGGKLLPLFNIVRFQNKPCGAGPLRGTCYTDKECNSRGGSNGG-PCAGGYGICCTFTPECXSQSSENLTYLTNNNPSAGPCSYRICKNNDWVCRLRFDFIDFTMAQPVLTRAGEGSSIGDCTTDQFSVTSANGGSPVICGTNTGQHIIVDASQDCNVATFVVGPQPFSGRSWNVRVTQYSCN-DESSPGGPPGCLQYFTEPTGVISSFNFPSNEKNANTFGTPTHLSNQMYTSCFRRNTNKCSICFTPTYTGG-AIESFGVSESTIKNGPGSGSGSDCTGDYIVINGARQPDESHLSAIENSNRLCGXILHTLRKKKVSTTICTEDTPFRISFKTDDDENTLGKTQST-NEVKGTPSGTVGFSLSYFQRDC 401          

Query:   40 DESRKGLSIFGFVRFQNTACNGTTRNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYLSK------GSDSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGG--------SIGDCTTD--SFSITGENGGSPVICGTNSGRHMIVDSIATCNMAQFFFGGGFN-NXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPTV------TGTMSKDSYGLGPSSNGIEAKSLVNEKCKGDFLEILSGIPFTSTNQMTVGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQ-DEMTPETGD-AVMNENKEEPRGTVGFSLTYKQFPC 405
            D   K LS+F  VRF+N  C G ++NGTCYTS EC  +GGL  G TCASGY     +TL CGGTSSENCTY+ +       S S++ CS+ IC    ++CRIR DF    ++DPVS    VG         + G CT D  +FS  G+N G+PVICG N+G+HMI+D+   CN+  F  G     +  + IKVTQ+ CG  +   AGPSGCLQYFT  SG    + F T      +   ATHL++Q+Y ICIRR    CR+CY P +        T  + SYG+  SSN   +KS  +  C  DF+EI  G    +    T    N+ICGR+F  A D + S +VCS  +PF++    D+ +E+T  T   A ++E  E P GT GF L Y Q  C
Sbjct:   27 DIEGKSLSLFNVVRFENIVCTGDSKNGTCYTSEECEAKGGLAQG-TCASGYGVCCIITLGCGGTSSENCTYIEQSSFTSSSSLSSNPCSYKICKLSDHVCRIRLDFTKHVLADPVSGTAVVGAVNVIDSRYAHGQCTEDRFTFSSIGKN-GAPVICGYNTGQHMILDASEQCNVLSFTVGSSTAVSREWSIKVTQYNCGDLN---AGPSGCLQYFTDDSGSFSTFNFRT--DSATVSATATHLANQEYSICIRRTANKCRVCYSPHINDPAADADTXPQASYGISLSSN-XASKSGADTDCTTDFIEI-PGAVANTVTVPTTXGTNRICGRFFAAARDAVDSATVCSLQVPFQINVNFDENEELTAVTATMAQLSELSEAPSGTTGFWLDYFQVAC 413          

Query:   39 IDESRKGLSIFGFVRFQNTACNGTTRNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYLSKGSDSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVDSIATCNMAQFFFGGG--FNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPTVTGTMSKDSYGLGPSSNGIEAKSLVNEKCKGDFLEILSGIPFTSTNQMT--VGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
            I   R    IF  V+FQN  C  TT  GTCYT++EC++RGG  AG  CASGY      T  CGGT +EN T L   S  T+DC++TIC    N+CRIR DF+ F +S P  +++  G + GDC TDSFS+T   G SPVICG NSG+H+IV++   CN A F   GG       ++I VTQF CG E     GP GCLQ+FT  +GV++++ + T  +       + HLS+QDY +C RR+ GNCRICY     G   K ++GL  S+N + A S V+  C  DF+EI  G    +  ++T  V +VNK CGR+ +T   + +  ++CSFS+PF  RF TD +E         +NE K +P G +GF L ++Q  C
Sbjct:   45 ISSERGERLIFNIVKFQNLPCGTTTNTGTCYTADECASRGG-TAGGACASGYGTCCMFTADCGGTITENSTLLEI-SSRTTDCTYTICRCSDNVCRIRLDFMTFVLSGP--TVSTDGANQGDCNTDSFSLTSSQGASPVICGFNSGQHIIVEADQGCNTALFNIDGGSTMVTRMWNINVTQFLCGDE---FGGPPGCLQFFTSNTGVVKSFNYNTVAT-------SNHLSNQDYNVCFRRQEGNCRICYSSFKVGI--KQTFGLSKSTNKLTA-SGVDTDCTEDFIEI-PGATQVTIKKVTKIVVSVNKNCGRFLDTNRLKTLPQTICSFSVPFRFRFKTDANEFIQVGKGPDLNEAKGDPSGLLGFKLFFEQKAC 402          

Query:   27 ISFMAFACQCSPID----------ESRKGLSIFGFVRFQNTACNGT-TRNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYLSKGS-DSTSD-----CSFTICPKHSNICRIRFDFIVFRISDPVSS----------ITNVGGSIGDCTTDSFSITGENG-GSPVICGTNSGRHMIVDSIATCNMAQFFFG-GGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPTVTGTMSKDSYGLGPSSNGIEAKSLVNEKCKGDFLEILSGIPFTSTNQMTVGAVNKICGRYFN 345
            IS +   C  + +D          +  K LSIF  V F NT C G+ ++NGTCYT++EC TRGG  +G +CASGY     +TL+CGGTSS+NCTY+ + S  STS      C++TIC   + ICRIR DF  F I++P ++          ITN G + GDC TDSFS T     GSPVICG NSG+HMI+D+   CN+  F  G     + ++ IK TQ+ CG  D +L GP GCLQYFTG +G I ++ +PTS +       ++HLS+Q Y IC R+E   C IC+   + G   ++++GL  S N   AKS V+ +C  D+L+I             V    K CGR  N
Sbjct:  315 ISLLILLCTINELDATANDVVEDKKDEKLLSIFNVVTFPNTFCTGSASKNGTCYTADECETRGGTASG-SCASGYGVCCXITLSCGGTSSDNCTYIEQSSFTSTSSLNSNPCTYTICKNSNMICRIRLDFTTFTIANPFTTPVGADAAGTTITNAGAT-GDCVTDSFSFTSPGSRGSPVICGANSGQHMILDASDECNVLNFNIGSSAATSRSWIIKATQYTCGDYD-SLGGPPGCLQYFTGTTGKISSFNYPTSETTTTT--SSSHLSNQCYSICFRQEATKCSICFASAIAG---QNTFGLSVSPNA-AAKSAVDSECTSDYLQI-PNGVAKGAAAAAVATTQKFCGRILN 657          

Query:   48 IFGFVRFQNTACN-GTTRNGTCYTSNECSTRGGLPAGDTCASG-----YVTLTCGGTSSENCTYLSKGSDSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIG--------DCTTDSFSITGENGGS-PVICGTNSGRHMIVDSIATCNMAQFFFGGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTG-QSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPT------VTGTMSKDSY-----GLGPSSNGIEAKSLVNEKCKGDFLEILSGIPFTSTNQMTVGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
            I+   RF+N   + G   NGTCYT++EC+ RGG P+GD CASG       T +CG TS+ENCTY    +     C   ICP   NIC++R DF  F I+ P ++  +VG +           C TD+F++T   G S PVICG NSG HM VDS   CN   F   G      ++IK+TQF C F++     P GC QYF G  +G+++ Y F              HL +Q+ RIC+RRE GNCRIC+  T      +TG ++K        G GP++ G+            D + I           +   A   +CG  F + D+Q    ++CS  LPF +RF++D    T ET      E  ++P    GF L+YK   C
Sbjct:   89 IWIIYRFRNDPXSTGDNTNGTCYTTDECTARGGTPSGD-CASGXGVCCVFTFSCGQTSAENCTYFIGQNVPDGQCRLEICPCSDNICQLRLDFTTFDITGPSTNTISVGKNAALKEVTNEQRCLTDTFAVTNPGGASPPVICGMNSGEHMYVDSSEQCNELAFNLQGANARQMWNIKITQFSCDFDN---LAPEGCTQYFFGSNTGIVKTYNFD----------GGQHLDNQNQRICVRRERGNCRICWTATADTDFELTGDLTKSIADGKCCGDGPANGGVSGT---------DCVIIPGASKEVDMKDLVKVAALGLCGGKFGSKDNQKAHKTICSMILPFNIRFLSD----TFETSGV---EKGKQPN---GFKLSYKMRAC 440          

Query:    2 VIFKFNQFKYITMERFSHLWKMLFLISFMAFACQCSPIDE-----------SRKGLSIFGFVRFQNTACNGTTRNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYLSKGSDSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVDSIATCNMAQFFFG-GGFNNXAFDIKVTQFEC 215
            +IFK N  +    E+   LW + FL+ F++ A      D+           S +GLS+F  VRF+N  C G   NGTCYT  +C TRGG+ +G TCASGY      +L CGG +SENCTYL   + S   C++TIC K + +CRIR DF  FRI  PVS  T   G++GDC T  FS+T  N GSP+ICG NSG+HMIVD+   CN+  F  G       +++IKVTQ+ C
Sbjct:   10 IIFKMNLAR--VTEQGLCLW-ITFLLLFISVASTQEEEDDEALLPEDSMAPSYRGLSLFNVVRFRNIPCIGFPLNGTCYTEEDCQTRGGVQSG-TCASGYGVCCSFSLNCGGMNSENCTYLVNNNPSPGACTYTICKKSNWVCRIRLDFADFRIGAPVSVATVDXGAVGDCVTXQFSVTXRNMGSPIICGMNSGQHMIVDADDNCNVVSFAIGAAAVPLRSWNIKVTQYNC 236          

Query:   14 MERFSHLWKML--FLISFMAFACQCSPIDESRKG---LSIFGFVRFQNTACNGTTRNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYLSKGSDSTSDCSFTICPKHSNICRIRFDFIVFRISDPVS----------SITNVGGSIG-----DCTTDSFSITGENGGSPVICGTN---SGRHMIVDSIATCNMAQFFFGGGFNNXA-----FDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPTVTGTMSKDSYGLGPSSNGIEAKSLV------NEKCKGDFLEILSGIPFTSTNQMTVGAVNKICGRYFNTADDQI-VSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
            M+RFS    +L  F  S +    +   + ++++    L +F  +RF+N AC+G ++NGTCYTS EC +RGG   G +CASG+      T  C G S ENCTY     +    CS TIC    ++C++R DF  F I+ P +           I + GG++       CTTD+F++T   G +P +   +   S   + VD+   CN   F FG      A     + IKV+Q   G  D ++A P GC QYFTG  GV+ +Y F         +GK THL+ Q+  IC+RRE G CRIC+      T  KD    G    G    S+         K  G    I   IP        +   N  CGR     D  +  + +VCS +LPF +RFV+D+ E   E                +GF L Y Q  C
Sbjct:    1 MDRFSMSLFLLCLFHYSLIILGSEEEALTKNQRESRLLPVFQVIRFRNDACSGGSKNGTCYTSAECESRGGTNGG-SCASGFGVCCTFTSRCSGMSRENCTYFESVGNEQGSCSLTICKCDESVCQLRLDFQSFMITGPSTLTETIGKTTFGILSAGGAVEVSDQTQCTTDTFTVTNPGGTTPPLKSVSQYLSIFKVYVDASDACNSLVFQFGANAPGVASVQRQWSIKVSQIRNG--DISMA-PKGCTQYFTGTKGVVRSYNF---------QGK-THLARQNQNICVRRERGMCRICW----AATGEKDFLLSGKEEKGFTKGSVCCGYGXDGXKTSGYDCVI---IPGAEKKTGKLANSNAFCGRSKGLVDMTMGDAKTVCSRALPFSIRFVSDKFEFKEEAAKLP----------NLGFQLAYTQDSC 401          

Query:   99 SSENCTYL------SKGSDSTSDCSFTICPKHSNICRIRFDFIVFRISDPV------SSITNVGGSIGDCTTDSFSITGENGG--SPVICGTNSGRHMIVDSIAT-CNMAQFFFGGGFNNX-AFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPTVTGTMSKDSYGLGPSSNGIEAKSLVNEKCKGDFLEILSG------IPFTSTNQMTVGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
            S+ NCTYL      S  S S + C++TIC   S  CR+R  F    ++ PV      ++  N+GG++GDCT D F I    GG  SP ICG N+G+HMIVD   T CN   F  G   +    + IK TQF C  +D    GP GCLQYFT  SG + +Y F TS S  V+   ATHLS+Q Y IC R+  GNC+ICY    T     +S+G+  S     A++ V   C  D++ I  G       P T TN       N+ C          IVS        PF L    D +E      D+  NE    P GT GF L Y Q PC
Sbjct:    2 SNANCTYLEQTSITSATSLSMNPCTYTICKCSSEACRLRLXFTTNILALPVIGTXXATAAENLGGALGDCTVD-FMILSSPGGQASPAICGFNTGQHMIVDMSDTGCNELTFNLGTASSTARQWSIKATQFVCN-DDNGSGGPPGCLQYFTEPSGTVASYNFDTSAS--VVAPTATHLSNQQYNICFRQGEGNCQICYTRHAT-----NSFGVSISPAAAAAQAGVGTVCSTDWITIPEGAVGPFPTPVTGTNPT---GNNRFC----------IVS--------PFVLGVNFDSNEANTGAADSSTNELAIIPGGTTGFWLDYTQNPC 300          

Query:   40 DESRKGLSIFGFVRFQNTACNGTT-RNGTCYTSNECSTRGGLPAGDTCASGY-----VTL-TCGGTSSENCTYL-----SKGSDSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVDSIATCNM--AQFFFGGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIP-TVTGTMSKDSYGLGPSSNGI-------EAKSLVNEKCKGDFLEI----------LSGIPFTSTNQMTVGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
            D S K +S+F  VRF NT C  +T  NGTC+TS+ECS  GG   G +CASG+     VT+  CG T+S N TY      +    +   CS  +    S+IC++R DFI F +++P ++      + G C  D F++TG++   P ICG+N+ +H+ +D               G   +  ++I+++Q  CG   T+   P  CLQYFT  +G I ++ +  + + LV      HL+ QDY ICIR   G C ICY+  T T T ++ ++ +  +   +          SLV+  C  D+L+I           +     S    T+G VNK+CG +F+       S  V S++ PF + F TD  E        +    +     + GF L+Y Q  C
Sbjct:   43 DRSSKFISLFSIVRFSNTPCTTSTGLNGTCFTSSECSKNGGTATG-SCASGFGVCCVVTIQNCGQTTSLNSTYWQNPGYTNTYTTAGQCSLYVTKSSSDICQLRLDFIGFTLANPDAT---AKLTAGQCLVDVFTVTGQSNSVPAICGSNANQHIYMDMTPGTQTFSLNMILTGTTTSRLWNIRISQIPCG---TSYTAPDNCLQYFTEPTGTITSFNYQYATTPLV-----QHLAYQDYNICIRTNQGFCGICYVACTATTTNAEPAFAISGTDTNVAAAAFAAATTSLVDTDCGNDWLQIPCATDQMNSVYTKASVASPTGPTLGCVNKLCGVFFSAVTAAAASAPVYSYTKPFNIYFHTDGSEYGMAAAGLITATTE-----SFGFCLSYTQQAC 423          

Query:   14 MERFSHLWKML-------FLISFMAFACQCSPI-------DESRKGLSIFGFVRFQNTACNGTT-RNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYLSKGS-----DSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVDS-IATCN--MAQFFFGGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYI---------------PTVTGTMSKDSYGLGPSSNGIEAKSLVNEKCKGDFLEILSGIP--FTSTNQMTVGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
            M+RF H W+ +          +F     Q   +       D  ++   +F  ++F N AC G    NGTC  + ECS R G+ +G  CA+GY     VT++CG  ++ N TY    +     D T+ C  T+   H  +C+ R DFI F I  P +  TN       C  D F I+G N   P ICG N+  H+ +D+ +   N     F   G     ++ I+V+Q  C   +T      GCLQYFTG SG I+++ +   I+ L        LS+QDY ICIR E   C I Y+                 +  TM  +++ L  ++   +  S+    C+ D+L I          TN MT   +++ICG  FN  +  + + S+ S   PF L F TD  E   + G+              GF L Y Q PC
Sbjct:    1 MKRFRHFWQTINNHENESLPFNFQKNKLQSLNVQNISNHGDREKRLFPLFTLIKFNNNACVGLNGENGTCIAATECSQRSGISSG-ICANGYGICCIVTVSCGDVTNNNNTYFVNPNYPSTFDGTTSCQLTLVKSHPTVCQFRLDFIHFNIRGPET--TN-----HQCIYDQFIISGGN-PIPTICGNNAENHLYIDAGLGQTNPVTLTFVISGQSFARSWKIQVSQIRC---NTIYRAEEGCLQYFTGISGQIKSFNY-DPITGL-------QLSNQDYSICIRMERNFCGIQYMICPIDDKEATMSNNGTPMMQTMYSNAFTLTGNTQATQIASMTGTICQTDWLTIPCAFNTGRLPTNMMT--CIDRICGGTFNAENQNLNASSIISTVKPFRLIFHTDSVEAPNDVGNK-------------GFCLNYIQQPC 402          

Query:   43 RKGLSIFGFVRFQNTACNGT-TRNGTCYTSNECSTRGGLPAGDTCASGY-----VTL-TCGGTSSENCTY-----LSKGSDSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVD---SIATCNMAQFFFGGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPTVTGTMSKDSYGLGPSSNGIEAK-SLVNEKCKGDFLEIL----SGIPFTSTNQMTVGAVNKICG--RYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
             K LS+F  VRF N  C  T + NGTC TS EC+T GG  +G TCASG+     VT+ TCG ++S N TY      S    +   CS  +    S++ ++R +F+ F ++ P S+  +   + G C TDSF+++G     P ICG+N+ +HM V+     +T  ++     G   +  ++I+V Q     ++T    P  CLQ+FT  +G + ++ +  + + +V      HL+ QDY +CIR   G C + Y    T T S   YG+   + G  A  ++++  C  D+L+I           ++   TVG  +K+CG   +  T D    + S+ S+  PFE+RF TD  E       A   EN        GF LTY Q PC
Sbjct:   45 EKFLSLFSIVRFPNVVCTATNSYNGTCLTSAECTTNGGTASG-TCASGFGVCCVVTIQTCGSSTSLNNTYWQNSGFSSAYTTAGQCSLFVSRASSDVDQLRLEFLTFTLAQPDSATLS---TTGQCITDSFTVSGSANIVPAICGSNANQHMYVNIGPGTSTVTLS-IITSGTTTSRYWNIRVIQIP---QNTDYTAPDNCLQWFTEAAGTLVSFNYQYAAAPIV-----QHLAYQDYTMCIRTNQGFCGVKY-ALCTPTASYP-YGISTVAAGTAAPGTVMDSSCAYDWLQIPCVTDQANSIVTSVGATVGCASKLCGILGFTVTTDSTTATTSLYSYRRPFEVRFYTDYKEFLVTAAAA---EN-------YGFCLTYTQQPC 404          

Query:    8 QFKYITMERFSHLWKML-------FLISFMAFACQCSPI-------DESRKGLSIFGFVRFQNTACNGTT-RNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYLSKGS-----DSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVDS-IATCN--MAQFFFGGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYI---------------PTVTGTMSKDSYGLGPSSNGIEAKSLVNEKCKGDFLEILSG-----IPFTSTNQMTVGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
            Q     ++RF H W+ +          +F     Q   +       D  ++   +F  ++F N AC G    NGTC  + ECS R G+ +G  CA+GY     VT++CG  ++ N TY    +     D T+ C  T+   H  +C+ R DFI F I  P    TN       C  D F I+G N   P ICG N+  H+ +D+ +   N     F   G     ++ I+V+Q  C   +T      GCLQYFTG SG I+++ +   I+ L        LS+QDY ICIR E   C I Y+                 +  TM  +++ L  ++   +  S+    C+ D+L I        +P   TN MT   +++ICG  FN  +  + + S+ S   PF L F TD  E   + G+              GF L Y Q PC
Sbjct:   56 QVSLKQVKRFRHFWQTINNHENESLPFNFQKNKLQSLNVQNISNHGDREKRLFPLFTLIKFNNNACVGLNGENGTCIAATECSQRSGISSG-ICANGYGICCIVTVSCGDVTNNNNTYFVNPNYPSTFDGTTSCQLTLVKSHPTVCQFRLDFIHFNIRGP--ETTN-----HQCIYDQFIISGGN-PIPTICGNNAENHLYIDAGLGQTNPVTLTFVISGQSFARSWKIQVSQIRC---NTIYRAEEGCLQYFTGISGQIKSFNY-DPITGL-------QLSNQDYSICIRMERNFCGIQYMICPIDDKEATMSNNGTPMMQTMYSNAFTLTGNTQATQIASMTGTICQTDWLTIPCAFNTGRLP---TNMMT--CIDRICGGTFNAENQNLNASSIISTVKPFRLIFHTDSVEAPNDVGNK-------------GFCLNYIQQPC 463          

Query:   43 RKGLSIFGFVRFQNTACNGT-TRNGTCYTSNECSTRGGLPAGDTCASGY-----VTL-TCGGTSSENCTY-----LSKGSDSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVD---SIATCNMAQFFFGGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPTVTGTMSKDSYGLGPSSNGIEAK-SLVNEKCKGDFLEI-----LSGIPFTSTNQMTVGAVNKICG--RYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
             K LS+F  VRF N  C  T + NGTC TS EC+  GG  +G TCASG+     VT+ TCG ++S N TY      S    +   CS  +    S++ ++R +F+ F ++ P S+  +   + G C TDSF+++G     P ICG+N+ +HM V+     +T  ++     G   +  ++I+V Q     ++T    P  CLQ+FT  +G + ++ +  + + +V      HL+ QDY +CIR   G C + Y    T T S   YG+   + G  A  ++++  C  D+L+I      +    TS   M VG  +K+CG   +  T D    + S+ S+  PFE+RF TD  E      +A   EN        GF LTY Q PC
Sbjct:   45 EKFLSLFSIVRFPNVVCTATNSYNGTCLTSAECTANGGTASG-TCASGFGVCCVVTIQTCGSSTSLNNTYWQNSGFSSAYTTAGQCSLFVSRASSDVDQLRLEFLTFTLAQPDSATLS---TTGQCITDSFTVSGSANIVPAICGSNANQHMYVNIGPGTSTVTLS-IITSGTTTSRYWNIRVIQIP---QNTDYTAPDNCLQWFTEAAGTLVSFNYQYAAAPIV-----QHLAYQDYTMCIRTNQGFCGVKY-ALCTPTASYP-YGISTIAAGTVATGTVMDSSCAYDWLQIPCVTDQANSIVTSVGAM-VGCASKLCGILGFTVTTDSTTATTSLYSYRRPFEVRFYTDSKEFLVTAAEA---EN-------YGFCLTYTQQPC 404          

Query:   46 LSIFGFVRFQNTACNGTT-RNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYL-----SKGSDSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVDS---IATCNMAQFFFGGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPTVTGTMSKDSY----GLGPSSNGIEA--KSLVNEKCKGDFLEILSGIPFTSTNQMTVGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
            LS+F  V FQN  C  ++  NGTC TS EC  RGG+ +G  CA G+        TCG  + ENC+Y       +  D T  C  T+   H NIC+ R DF  F I+ P   I N+      C  D F ++G N   P ICG N+G HM +D+   I       F   G   +  + +K+ Q  C   D+ +    GCLQYFTG SG I++Y +          G    LS+QDY ICIR E   C I Y P V    +  S     G   S N + A   S   + C  D+L I       +        V++ICG  FN ++  +   ++ S   PF L + TD  E   +  +              GF L Y Q PC
Sbjct:   65 LSLFTVVEFQNQGCGASSGDNGTCLTSAECEERGGVSSG-PCARGFGICCVFLATCGQDTKENCSYFVSPNFPQSYDGTGSCQLTVHKSHPNICQFRLDFDQFNIAGP-EPINNI------CNNDQFIVSGGN-TVPGICGMNNGNHMYIDAGSGITNPVTLTFVTSGPSFDRTWKVKICQIPC---DSVIKAEDGCLQYFTGVSGQIKSYNYD--------PGAGLQLSNQDYSICIRSERNFCGIHYSPCVDPVNNFSSAFTLSGNTLSQNQVAAIIGSDGPQPCDSDWLIIPCASNVGTIRDGPYPCVDRICGGTFN-SEVSLTPATLLSTVKPFRLIYHTDGAEYPDDASNH-------------GFCLNYIQQPC 410          

Query:   14 MERFSHLWKMLFLISFMAFACQCSPIDESRKGLSIFGFVRFQNTACNGTT-RNGTCYTSNECSTRGGLPAGDTCASGYVTL-----TCGGTSSENCTYLSKGS-----DSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVDSIATCNMAQFFFGGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSIS-ELVIEGK------ATHLSSQDYRICIRRETGNCRICYI--PTVTG-TMSKDSYGLGPSSNGIEAKSLVNEKCKGDFLEILSGIPFTSTNQMTVGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
            M+R   +  + +    ++   Q   I+         G VRF NT CN      GTCYT  EC   GG+ +G +CA+G  T      TCGG SS N TY +         ++S C+FTI   +S+IC++R DF+   ++ P  +        G+C TDS  I+G     P+ICG       I+  IAT       F   +N     IK+TQ  C   D     P+GCL Y+T  SG + ++ + T++S  LVI            L++++Y +C++ + G C I +   P  T  T+S D+     SS G+    ++   C  DF+ I + I     N  TVGA ++ CG    T         V S S PF L  VTD+++++      V N          GFSLTY+Q PC
Sbjct:    1 MKRVLIVLLLTYFQPILSKTDQPVSINFRHSKFWPVGVVRFPNTVCNSLEGYTGTCYTKWECHNLGGVASG-SCANGIGTCCIFQGTCGGNSSYNNTYFTNRGFPNTVSNSSSCTFTIKKCNSDICQVRLDFLNLNLAQPDGN--------GNCITDSLIISGGASNLPIICGQTVANTDIILMIAT---GALTFARSWN-----IKITQLAC---DCPSLAPTGCLMYYTALSGTVNSFNYGTTLSGGLVINPMNMTRPGTRQLANENYGVCVQMQPGYCAIEWSQGPGDTSFTVSNDTAFADASSVGLPGFPVIGTMCNTDFVVIPNPI---YANGTTVGA-DRFCGNQLPT---------VISSSKPFVLTVVTDENDVS-----DVANR---------GFSLTYRQIPC 366          

Query:   37 SPIDESRKG--LSIFGFVRFQNTACNGTTRN-GTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYLSK----GS-DSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVD-------SIATCNMAQFFFGGGFNNXA-FDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICY--------IP----TVTGTMSKDSYGLGPSSNGIEAKSLVNEKCKGDFLEILSGIPFTSTNQMTVGAV--NKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
            +P+ + R G    +F  V   N AC   + + GTC +  EC    G  +G TC  GY      T TC G    N TY       GS  S   C  T+     NIC++R DF  F I+ P  +          C +DSF I+G     PVICG N+G+HM ++        I    +      GGF +   + I+V+Q  C   +   A P GCLQY+TG  GVI ++ F      +     A  LS QDY ICIR+E+  C + Y        +P    +++G +     G G  S+G +A       C  DFL I  G         + GAV   ++CG  +N+ + + +S  V + S+PFELR+ T+              E+ E  +G +GF LTY+Q PC
Sbjct:   34 NPVYDVRDGKFFGLFETVINNNRACRALSGDIGTCLSYPECFAFRGNISG-TCGRGYGLCCVTTKTCQGVIYANNTYFVNQGYPGSYTSAGQCYTTVNRLAPNICQLRLDFEAFSIAQPEPAEHR-------CVSDSFVISGTTSPVPVICGDNAGQHMYLNIGYNSTTPITLTMITSNLMAGGFTSARNWKIRVSQIPC---NEGFAAPPGCLQYYTGSVGVIRSFNFFFDSRGV---NTARQLSFQDYTICIRQESNFCEMQYNVCPDQVNVPGLGFSISGALVA---GEGTVSSGADA------ACTADFLMIPCGSDVRGQPTKSNGAVCAARLCGSVWNSINAETLSRPVFTRSVPFELRYYTNGL------------ESSEGDQGNLGFCLTYQQEPC 402          

Query:   44 KGLSIFGFVRFQNTACNGTTR-NGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYLSKGSDSTS-----DCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVDSIATCNMAQFFFGGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPTVTG--TMSKDSYGLGPSSNGIEAKSLVNEKCKGDFLEILSGIPFTSTNQMTVGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
            K   +F  +RF N+ C  +   NGTC+T  EC   GG P+G TCA+G+        TC  T++ N TY       T+      C+ T+   +SNIC++R DF+ F ++ P +S        G C  +   ++G     P ICG N+ +H+ VD      +             ++I++ Q  C   D+T   P+GCLQY+   S ++ ++ + T+ +    E     +++ +Y +CIR   G C I +  T +   ++S D+     +  G E  +   E C  DF+     IP    N + +G   + CG  F         ++  S+S PF L  +T+ +E           ENK       GFSLTY+Q PC
Sbjct:   36 KFFPLFSVIRFANSQCLASNNLNGTCFTRRECRDYGGTPSG-TCANGHGICCVFQKTCSSTTNVNNTYFINPEYPTTYEGQGRCTITVQRCNSNICQLRLDFLEFTLASPNAS--------GICDFEFLLVSGSGSIVPRICGENANQHLYVDFNGDTPIMISVDTNSKYKDRWNIRIQQLSC---DSTYKAPNGCLQYYDSVSNIVTSFNYGTTQNPRAPEFGTRQIANTNYGVCIRMAQGYCAIEWSQTNSNSFSVSGDTGSFDSTIIGTEYAAQAGENCTQDFVI----IPHPFQNGIAIGT-ERFCGNGF---------VTKTSYSKPFVLYVITNGNEFEEV-------ENK-------GFSLTYRQIPC 370          

Query:   46 LSIFGFVRFQNTACNGTT-RNGTCYTSNECSTRGGLPAGDTCASGYVT-----LTCGGTSSENCTYL-----SKGSDSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVDS-IATCN--MAQFFFGGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIP---TVTGTMSKDSYGLGPSSNGIEAKSLVN-------EKCKGDFL-----EILSGIPFTSTNQMTVGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
            L IF   ++    C+  +   G+C  +NEC  RGG+PAG  CA GY T      +CGG   EN TY         +D T  C  TI   H +IC++R DF  F ++ P   I N       C TD F ++G    +P ICG+ +G HM +D+ +   N  +      G     ++ ++++Q  CG          GCLQY TG SG ++++ F        + G+   LS+QDY ICIR E   C I Y      V G  S+ ++ L  +SN +  +++V          C  D+L     +I   +P  ST +      +KICG  FN A+   V  +V S   PF L F TD  E   +       +N+       GF L Y Q PC
Sbjct:    1 LPIFTVYQWGQGLCSAASGEYGSCQPNNECVLRGGIPAG-PCAGGYGTCCIFMASCGGVVRENGTYFVNPNHPDSTDGTGSCQLTILKMHPDICQVRLDFDHFSLNGP--EIVN-----HICNTDQFLVSG-GSPAPTICGSATGEHMYIDAGMGQSNPIILTVITSGPSFPRSWRVRISQIPCG---AIAKADQGCLQYHTGVSGRVKSFNFDP------LSGR--QLSNQDYSICIRTERNFCSIQYTACPGAVPGNRSR-TFTLSGNSNSV-VQAMVGGGTQGSPNSCTNDWLMVPCAKIADRLPMASTCE------DKICGGTFN-AEVSSVERTVVSTIRPFRLAFHTDSIEAPTDV------DNR-------GFCLDYVQQPC 347          

Query:   40 DESRKGLSIFGFVRFQNTACNGTT-RNGTCYTSNECSTRGGLPAGDTCASGY-----VTL-TCGGTSSENCTYL-----SKGSDSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVDSIA-----TCNMAQFFFGGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIP-TVTGTMSKDSYGLGPSSNGIEA-----------KSLVNEKCKGDFLEI----------LSGIPFTSTNQMTVGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
            D S K +S+F  VRF N  C  +T  NGTC+TS+ECS+ GG   G +CASG+     VT+ TCG T++ N TY      +    +   CS  +    S+IC++R DFI F +++P S   N   S G C  D F++TG++   P ICG+N+ +H+ +D        + NM      G   +  ++I+++Q  CG   T+   P  CLQYFT  +G + ++ +  + + ++      HL+ QDY ICIR   G C I Y P + T T  + S+ +    +GI+             SLV+ +C  D+L+I           +     +    TVG VNK+CG +F+       +  V S++ PF L F TD  E    T DA+    +     + GF LTY Q  C
Sbjct:  124 DRSSKFISLFSIVRFSNAPCTTSTGLNGTCFTSSECSSNGGTATG-SCASGFGVCCVVTIQTCGSTTALNSTYWQNPGYTNTYTTAGQCSLYVTKSSSHICQLRLDFIGFTLANPDS---NAKVSAGQCLVDVFTVTGQSNSVPAICGSNANQHIYMDMTPGTQTFSLNM---ILTGTTTSRLWNIRISQIPCG---TSYTAPENCLQYFTEPTGTLTSFNYQYATTPVI-----QHLAYQDYNICIRTNQGFCGISYAPCSTTTTNGEASFAI----SGIDTAVAAAAFAAGTTSLVDAECGNDWLQISCATDQINSVYTSASVAAPTGPTVGCVNKLCGVFFSAITAAAANAPVYSYTKPFNLYFHTDGSEFGMATADAIGTSTE-----SFGFCLTYTQLAC 504          

Query:   41 ESRKGLSIFGFVRFQNTACNGTT-RNGTCYTSNECSTRGGLPAGDTCASGY-----VTL-TCGGTSSENCTYL-----SKGSDSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVDSIA-----TCNMAQFFFGGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIP-TVTGTMSKDSYGLGPSSNGIEA-----------KSLVNEKCKGDFLEI----------LSGIPFTSTNQMTVGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
             S K +S+F  VRF N  C  +T  NGTC+TS+ECS+ GG   G +CASG+     VT+ TCG T++ N TY      +    +   CS  +    S+IC++R DFI F +++P S   N   S G C  D F++TG++   P ICG+N+ +H+ +D        + NM      G   +  ++I+++Q  CG   T+   P  CLQYFT  +G + ++ +  + + ++      HL+ QDY ICIR   G C I Y P + T T  + S+ +    +GI+             SLV+ +C  D+L+I           +     +    TVG VNK+CG +F+       +  V S++ PF L F TD  E    T DA+    +     + GF LTY Q  C
Sbjct:   98 RSSKFISLFSIVRFSNAPCTTSTGLNGTCFTSSECSSNGGTATG-SCASGFGVCCVVTIQTCGSTTALNSTYWQNPGYTNTYTTAGQCSLYVTKSSSHICQLRLDFIGFTLANPDS---NAKVSAGQCLVDVFTVTGQSNSVPAICGSNANQHIYMDMTPGTQTFSLNM---ILTGTTTSRLWNIRISQIPCG---TSYTAPENCLQYFTEPTGTLTSFNYQYATTPVI-----QHLAYQDYNICIRTNQGFCGISYAPCSTTTTNGEASFAI----SGIDTAVAAAAFAAGTTSLVDAECGNDWLQIPCATDQINSVYTSASVAAPTGPTVGCVNKLCGVFFSAITAAAANAPVYSYTKPFNLYFHTDGSEFGMATADAIGTSTE-----SFGFCLTYTQLAC 477          

Query:   40 DESRKGLSIFGFVRFQNTACNGTT-RNGTCYTSNECSTRGGLPAGDTCASGY-----VTL-TCGGTSSENCTYL-----SKGSDSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVDSIATCNM--AQFFFGGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIP-TVTGTMSKDSYGLGPSSNGI-------EAKSLVNEKCKGDFLEI----------LSGIPFTSTNQMTVGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
            D S K +S+F  VRF NT C  +T  NGTC+TS+ECS  GG   G +CASG+     VT+  CG T+S N TY      +    +   CS  +    S+IC++R DFI F +++P ++      + G C  D F++TG++   P ICG+N+ +H+ +D               G   +  ++I+++Q  CG   T+   P  CLQYFT  +G I ++ +  + + LV      HL+ QDY ICIR   G C ICY+  T T T ++ ++ +  +   +          SLV+  C  D+L+I           +     S    T+G VNK+CG +F+       S  V S++ PF + F TD  E        +    +     + GF L+Y Q  C
Sbjct:   43 DRSSKFISLFSIVRFSNTPCTTSTGLNGTCFTSSECSKNGGTATG-SCASGFGVCCVVTIQNCGQTTSLNSTYWQNPGYTNTYTTAGQCSLYVTKSSSDICQLRLDFIGFTLANPDAT---AKLTAGQCLVDVFTVTGQSNSVPAICGSNANQHIYMDMTPGTQTFSLNMILTGTTTSRLWNIRISQIPCG---TSYTAPDNCLQYFTEPTGTITSFNYQYATTPLV-----QHLAYQDYNICIRTNQGFCGICYVACTATTTNAEPAFAISGTDTNVAAAAFAAATTSLVDTDCGNDWLQIPCATDQMNSVYTKASVASPTGPTLGCVNKLCGVFFSAVTAAAASAPVYSYTKPFNIYFHTDGSEYGMAAAGLITATTE-----SFGFCLSYTQQAC 423          

Query:   41 ESRKGLSIFGFVRFQNTACNGTT-RNGTCYTSNECSTRGGLPAGDTCASGY----------VTLTCGGTSSENCTYLSKGS-----DSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVDS-IATCNMAQFFFGGGFNN--XAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAF-PTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIP------TVT---GTMSK-DSYGLGPSSNGIEAKSLVNEKCKGDFLEILSGIPFTSTNQMTVGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
              ++   +F  VRF+N  C G    NGTC ++ ECS RGG+ +G  CA+GY          V ++CG T ++N TY    +     D T  C  T+   + ++C+ R DF+ F I  P  +  N+      CT D F ++G N   P ICGTN+G HM +D+ +   N     F    N+   ++ ++++Q  C    T      GCLQYFTG SG I+++ F PT+            LS+QDY ICIR E   C I Y+P       VT   G MS+ +++ L  ++ G +  S+    C+ D+L I   I    T  M++  V+++CG  FN     + S SV S   PF L F TD  E   + G+              GF L Y Q PC
Sbjct:   39 REKRLFPLFTVVRFENNICGGLNGENGTCISATECSQRGGISSG-ICANGYGVCCIDYYFEVMVSCGQTINDNNTYFVNPNYPSTFDGTESCQLTLLKSNPDVCQFRLDFVQFMIRGP-ETTNNL------CTYDQFIVSGGNP-VPTICGTNNGNHMYIDAGVGQTNPITLTFVTSGNSFPRSWKVRISQIRC---STIYRAEEGCLQYFTGVSGQIKSFNFDPTT---------GLQLSNQDYSICIRMEKNFCGIQYMPCSDEGTMVTSGPGQMSRSNAFTLTGNTQGTQIASMTGAACQTDYLMIPCAINAGRTPSMSITCVDRLCGGTFNAESQNLNSSSVISTVKPFRLIFHTDAIEAPNDVGNR-------------GFCLNYVQQPC 399          

Query:   41 ESRKGLSIFGFVRFQNTACNGTT-RNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYLSKGS-----DSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVDS-IATCNMAQFFFGGGFNN--XAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAF-PTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIP------TVT---GTMSKD-SYGLGPSSNGIEAKSLVNEKCKGDFLEILSGIPFTSTNQMTVGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
              ++   +F  V+F N  C G+   NGTC ++ ECS R G+ +G  CA+GY     V ++CG T ++N TY    +     D T  C  T+   + ++C+ R DF+ F I  P  +  N+      CT D F ++G N   P ICGTN+G HM +D+ +   N     F    N+   ++ ++++Q  C    T      GCLQYFTG SG I+++ F PT+            LS+QDY ICIR E   C I Y+P       VT   G MS++ ++ L  ++ G +  S+    C+ D+L I   I    T  M++  V+++CG  FN     + S SV S   PF L F TD  E   + G+              GF L Y Q PC
Sbjct:   67 REKRLFPLFTVVKFDNNVCAGSNGENGTCISATECSQRAGISSG-ICANGYGVCCIVMVSCGQTINDNNTYFVNPNYPSTFDGTESCQLTLLKSNPDVCQFRLDFVQFMIRGP-ETTNNL------CTYDQFIVSGGNP-VPTICGTNNGNHMYIDAGVGQTNPITLTFVTSGNSFPRSWKVRISQIRC---STIYRAEEGCLQYFTGVSGQIKSFNFDPTT---------GLQLSNQDYSICIRMEKNFCGIQYMPCSDEGIMVTSGPGQMSRNNAFTLTGNTQGTQIASMTGAACQTDYLMIPCAINAGRTPSMSITCVDRLCGGTFNAESQNLNSSSVISTVKPFRLIFHTDAIEAPNDIGNR-------------GFCLNYVQQPC 422          

Query:   43 RKGLSIFGFVRFQNTACNGTT-RNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYLSKGS-----DSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVDS-IATCNMAQFFF---GGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYI-------------PTVTGTMSKDSYGLGPSSNGIEAKSLVNEKCKGDFLEILSGIPFTSTNQMTVGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
            R+ LS+F  V+F N  C G +  NGTC++S ECS RGG+ +G  CA+GY     VT++CG T S N TY    +     D+T  C  TI   H  +C+ R DF+ F++  P  +I +V      CT+D F  +G N   P ICG N+G HM +D+ I   N     F   G  F   ++ ++++Q  C   ++      GCLQ++TG SG I+++ +        I G    LS+QDY ICIR E   C + Y+             P V+  + K+ + L  ++   +  S+    C+ D+L I   +       + +  V++ICG  F      + S SV S   PF L F TD  E   +  +              GF L Y Q PC
Sbjct:  136 RRFLSLFTLVQFGNDLCGGLSGENGTCFSSAECSQRGGVSSG-VCANGYGVCCIVTVSCGQTISNNNTYFVNPNYPSTFDATESCQLTILKSHPQVCQFRLDFLQFKLRGP-ETINHV------CTSDQFIASGSNP-VPTICGNNNGNHMYIDAGIGQTNPVTLTFVTSGSSFAR-SWKVRISQIPC---NSPAKADEGCLQFYTGVSGQIKSFNYD------AING--LQLSNQDYSICIRMERNFCGVQYMSCQESLSTTDVLAPGVSQMIPKNGFSLTGNTQATQIASMTGAACQTDWLMIPCVLNLNRLGNIGIACVDRICGGTFAAESQSLNSSSVISTVKPFRLVFHTDSTEAPNDVSNR-------------GFCLNYVQQPC 492          

Query:   43 RKGLSIFGFVRFQNTACNGTT-RNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYLSKGS-----DSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVDS-IATCNMAQFFF---GGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYI-------------PTVTGTMSKDSYGLGPSSNGIEAKSLVNEKCKGDFLEILSGIPFTSTNQMTVGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
            R+ LS+F  V+F N  C G +  NGTC++S ECS RGG+ +G  CA+GY     VT++CG T S N TY    +     D+T  C  TI   H  +C+ R DF+ F++  P  +I +V      CT+D F  +G N   P ICG N+G HM +D+ I   N     F   G  F   ++ ++++Q  C   ++      GCLQ++TG SG I+++ +        I G    LS+QDY ICIR E   C + Y+             P V+  + K+ + L  ++   +  S+    C+ D+L I   +       + +  V++ICG  F      + S SV S   PF L F TD  E   +  +              GF L Y Q PC
Sbjct:  140 RRFLSLFTLVQFGNDLCGGLSGENGTCFSSAECSQRGGVSSG-VCANGYGVCCIVTVSCGQTISNNNTYFVNPNYPSTFDATESCQLTILKSHPQVCQFRLDFLQFKLRGP-ETINHV------CTSDQFIASGSNP-VPTICGNNNGNHMYIDAGIGQTNPVTLTFVTSGSSFAR-SWKVRISQIPC---NSPAKADEGCLQFYTGVSGQIKSFNYD------AING--LQLSNQDYSICIRMERNFCGVQYMSCQESLSTTDVLAPGVSQMIPKNGFSLTGNTQATQIASMTGAACQTDWLMIPCVLNLNRLGNIGIACVDRICGGTFAAESQSLNSSSVISTVKPFRLVFHTDSTEAPNDVSNR-------------GFCLNYVQQPC 496          

Query:   41 ESRKGLSIFGFVRFQNTACNGTT-RNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYLSKGS-----DSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVDS-IATCN--MAQFFFGGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIP-------TVTGTMSKDS----YGLGPSSNGIEAKSLVNEKCKGDFLEILSGIPFTSTNQMTVGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
              R+ LS+F  V+F N+ C+G    NGTC ++ ECSTRGG+ +G  CA+GY     +T  CG T+S N TY    +     D T  C  TI   H ++C+ R DF  F I  P    TN       CT D F ++G N   P ICG+N+G HM VD+ +   N  M  F   GG    ++ +++    C    +      GCLQYFTG SG I+++ +  +            LS+QDY ICIR E   C + Y+P       T  G   + S    + L  ++ G +  S+    C+ D+L I             V   ++ICG  FN  +  + S +V S   PF L F TD  E   + G+              GF L Y Q PC
Sbjct:   67 RDRRFLSLFTLVQFDNSLCSGMNGENGTCISAAECSTRGGV-SGGPCANGYGVCCALTAMCGQTTSTNNTYFVNMNYPSTFDGTDSCQLTILKSHPDVCQFRLDFDQFNIRGP--EPTN-----NACTNDQFIVSGGN-PIPPICGSNNGNHMYVDAGVGQVNPVMLTFVTSGGSFARSWKVRIIHVPC---SSIYRAEEGCLQYFTGVSGKIKSFNYEPNT--------GLQLSNQDYSICIRMERNFCGVQYMPCSDADAATPQGGRPQPSRSNAFTLTGNTQGTQISSMTGAACQTDWLMIPCASNMGRQPNTGVQCTDRICGGTFNAENQVLNSSNVISTVKPFRLVFHTDSVEAPNDVGNR-------------GFCLDYIQQPC 423          

Query:   46 LSIFGFVRFQNTACNGTT-RNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYLSKGS-----DSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVD-SIATCNMAQFFF---GGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPTVTGT---------------MSKDSYGLGPSSNGIEAKSLVNEKCKGDFLEILSGIPFTSTNQMTVGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
            LS+F  VRF+N  C G +  NGTC +  EC+ RGGL +G  CASGY     VT++CG ++ +N TY    S     D T  C  TI   HS+IC+ R DF+ F +  P  ++ N+      CT D F ++G N  SP ICG N+G HM +D      N     F   G GF+  ++ +++ Q  C    +      GC+QY+TG SG I+++ +  +I           LS+QDY ICIR E   C I Y+    G+               M   S+ L  ++   +  ++ +  C+ D+L +             +  V++ICG  FNT +  + S S+ S   PF L F TD  E   + G+              GF L Y Q PC
Sbjct:  151 LSLFTLVRFENNVCMGVSGENGTCISPAECAQRGGLSSG-ICASGYGVCCIVTVSCGQSTFDNNTYFVNPSYPSTFDGTDSCQLTIIKSHSDICQFRLDFVQFNVKGP-ETLNNL------CTYDQFIVSGGNPISP-ICGNNNGNHMYIDVGTGPTNPVTLSFVTSGSGFDR-SWRVRIAQIPCS---SIFRAEEGCMQYYTGVSGQIKSFNYDPNI--------GLQLSNQDYSICIRMERNFCGIQYMTCDDGSKIANPMANAMSMQQMMRSSSFTLSGNTINGQYTAMTDRSCQNDWLMMPCAGNSGRLPSSQISCVDRICGGAFNT-ETSVNSTSIISTVKPFRLVFHTDGTEAPNDFGNR-------------GFCLNYVQQPC 505          

Query:   41 ESRKGLSIFGFVRFQNTACNGTT-RNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYL-----SKGSDSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVD-SIATCNMAQFFF---GGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIP-----------------TVTGTMSKDSYGLGPSSNGIEAKSLVNEKCKGDFLEILSGIPFTSTNQMTVGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
              ++ LS+F  VRF+N  C G++  NGTC +  EC+ RGGL +G TCA+GY     V+++CG ++ +N TY        G D T+ C  T+  +H ++C+ R DF+ F I  P  +I N+      CT D F ++G N  SP ICG N+G HM +D      N     F   G GF   ++ ++V Q  C    +      GCLQY+TG SG ++++ F   +           LS+QDY ICIR E   C I Y+                  +  G     S+ L  ++   +  ++V+  C+ D+L I             +  V++ CG  FN A+  + S S+ S   PF L F +D  E   + G+              GF L Y Q PC
Sbjct:   55 RDQRLLSLFTLVRFENNICVGSSGENGTCISPAECAQRGGLASG-TCANGYGVCCIVSVSCGQSTYDNNTYFVNPNYPSGFDGTNSCQLTVLKQHPDVCQFRLDFVQFSIRGP-ENINNL------CTYDQFIVSGGNPVSP-ICGNNNGNHMYIDVGTGPTNPVILSFVTSGSGFER-SWRVRVAQIPC---SSIFRAEEGCLQYYTGVSGQVKSFNFDPIV--------GLQLSNQDYSICIRMERNFCGIQYMACEDVNSLQSGINSVGFGSPGGQQIPRSFTLSGNTLNGQLAAMVDRACQSDWLMIPCAANAGRLQTNQIPCVDRFCGGAFN-AEASVNSTSIISTVKPFRLYFHSDGTEAPNDYGNR-------------GFCLNYVQQPC 416          

Query:   91 VTLTCGGTSSENCTYLSKGSDSTSD-CSFTICPKHSNICRIRFDFIVFRISDPVSSITNVG-----GSIGDCTTDSFSITGE-NGGSPVICGTNSGRHMIVDSIATCNMAQFFFGGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPTVTGT-----MSKDSYGLGPSSNGIEAKSLVNEKCKGDFLEILSGIPFTSTNQM------TVGAVNKICGRYFN-----------TADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
            V+L CGG+SSENCTYL++ S ++S  C + IC   SNICRIR DF  F I+ P      +      G+IGDCT+D FS+T     G+PVICG NSG+HMI+D+ A C+ A F  G    + ++DIK+TQF C      LAG SGCLQYFTG SG + ++ FPT+ + +     ATHLS Q+Y +CIRRE G C ICY+P    T     +++  +GL   +  I A+S    +C  D+L I        T  +      T     +ICGR F+             D     +SVC+   PF + F TD +E++    D+ M+E KE P G VGFSL Y+Q  C
Sbjct:   24 VSLGCGGSSSENCTYLTQTSTTSSGSCVYNICKCSSNICRIRLDFTTFNIARPYEGTLEMAALSDAGAIGDCTSDQFSVTSPGRAGTPVICGFNSGQHMIIDASADCHKAAFTLGSSTTSRSWDIKITQFSC---KDNLAGSSGCLQYFTGVSGTVSSFNFPTTATAIPA--TATHLSEQNYNLCIRREAGYCSICYVPVFADTTNNAVIAQAGFGLSNPA-AIVAESASGSQCSSDYLIIPGADDIGGTETLPTKVLPTAPTEGRICGRIFSAETGKAAAMVYATDRSTTDVSVCTQVTPFLITFKTDGNEVSTADSDSSMSELKEFPGGIVGFSLNYRQQKC 361          

Query:   92 TLTCGGTSSENCTYLSKG---SDSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVGGSIGDCTTDSFSITGENGGSPVICGTNSGRHMIVD-SIATCNMAQFFFGGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPTVTGTM----SKDSYGLGPSSNGIEAKSLVNEKCKGDFLEILSGIPFTS-----TNQMTVGAVNKICGRYFNTADDQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQFPC 405
            ++ CGG++S+NCTY +     ++S S C + IC   ++ICRIR DFIV   SD          +IG C TD F++ G N   P+ICG N+G+HMI D     C    F  G G     ++IK+TQ++CG +D  +AGP+GC QYFTG SG   +Y FPT+     I    THL+ Q Y IC+RRE G C ICY+P+V        ++ S+G+   S+G +  S     C  DF++I  G+ F        + M VG V ++CGR+FN        +SVCS + PF+L F  + +E+   T +A  NE  + P G VGFSL YKQ PC
Sbjct:    1 SIGCGGSTSDNCTYAASATSNANSQSSCRYEICKCSNDICRIRLDFIV---SD----------AIGACITDQFTLVGANSPPPLICGYNTGQHMIYDVGQDDCAEMAFVLGSGSVTREWEIKITQYKCGHDD--IAGPNGCQQYFTGTSGSFASYNFPTNSD--TIGATTTHLNRQQYTICLRREQGFCAICYVPSVVAVTDAAETQSSFGVS-KSDGAQTDS----DCFQDFIQIGYGVNFEDLMMPLEDLMPVG-VQRLCGRFFNAKSGGKTHVSVCSSTNPFQLIFQANGNELNIAT-EATRNELIDPPGGIVGFSLDYKQVPC 303          

Query:   44 KGLSIFGFVRFQNTACNGTTRNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYLSK----GSDSTSDCSFTICPKHSNICRIRFDFIVFRISDP--------VSSITNVGGSIGDCTTDSFSI---------------TGENGGS-------------------PVICGTNSGRHMIVDSIATCNMAQFFFGGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYR---ICIRRETGNCRICYIPTVTGTMSKDSYGLGPSSNGIEAKSLVNEKCKGDFLEILSGIPFTSTNQMTVGA--VNKICGRYFNTA---DDQIVSI-SVCSFSLPFELRFVTDQDEMT-PETGDAVMNENKEEPRGTVGFSLTY 400
            K LS+F  VRF+N  C   +RNGTCYT NEC+  GG+ +G TCA GY      TL CG T+ +NCTYL++    G    + C +TIC     +CRIR DF+ F ++ P          +I+  GGSIGDC TD F I               TG++ GS                   P ICG N+G+HMIVD+   C++A F      +  A+DIKVTQ+ CG E   +AGP GCLQYFTG  G I +Y FPT  S +V      +    +      C++  TGN          GT++  SY     SN I   +L +         I++  P     Q   G   + +ICGRYFN A    D+I ++ S+CSF  PF++ F TD DE+T   T    +NE  E P G  GF L +
Sbjct:   48 KVLSLFQIVRFKNDPCISASRNGTCYTGNECTENGGVASG-TCAGGYGVCCVFTLACGQTTRDNCTYLTRNNGGGGHGMAACHYTICKCSEQVCRIRLDFLNFDLAPPGLGTTVMGGVAISTNGGSIGDCLTDQFVITAPGNVSPPQICGFNTGQHSGSIGDCLTDQFVITAPGNVSPPQICGFNTGQHMIVDASDECHVASFNL--ARSTSAYDIKVTQYWCGDE---MAGPDGCLQYFTGNMGTIASYNFPTQ-SNMVTPQITQYWCGDEMAGPDGCLQYFTGN---------MGTIA--SYNFPTQSNMIPG-ALRD--------SIIASAPMFVVGQTPDGEKHITRICGRYFNIATARQDRIDNLESICSFQRPFQVIFKTDMDEVTLAATNMPDVNEQSEAPGGITGFHLNW 438          

Query:   40 DESRKGLSIFGFVRFQNTACNGTT-RNGTCYTSNECSTRGGLPAGDTCASGY---VTLTCGGTSSENCTYLSKGSDSTSDCSFTICPKHSNICRIRFDFIVFRIS---------------DPVSSITNVGGSIGDCTTDSFSITGENGGS-PVICGTNSGRHMIVDSIATCNMAQFFFGGGFNNXA-----FDIKVTQFECGFEDTTLAGPSGCLQYFTGQ-SGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPT------VTGTMSKDSYGLGPSSNGIEAKSLVNEKCKGDFLEILSGIPFTSTNQMTVGAVNKICGRYFNTADDQIV--SISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQ 402
            +  +K LS F  + F N  C+G++ +NGTCYT++EC  +GG  AG +CA GY    T  CG +SSENCTY  +      +CS  IC   SNIC++R DF  F I+               DPV++          C TDSF++T   G S P ICG NS  HM VD+  +CN   F  G   N  A     + IKVTQ+ C +E+     P+GC QYF G  +G +  Y +   +          HL++Q+  ICIRRET  CRIC+ PT      V+GT++   + +  S  G  A     +  KG   + LS IP   +  +    V++ CG     A   +V    + C+ +LPF +RF +D  E   E       +NK       GF L Y+Q
Sbjct:   23 ERQKKFLSAFQIITFNNDPCSGSSSKNGTCYTASECEAKGGTSAG-SCAQGYGVCCTSKCGVSSSENCTYFEQSGGEVGECSVQICKCRSNICQLRLDFEQFTITGPSTFTLSSVKLLNGDPVAAAGADANLQSQCLTDSFTVTNPGGTSPPTICGINSDEHMYVDASPSCNDLVFQLGNTGNGAALSTRRWSIKVTQYTCDYENL---APTGCTQYFFGSPTGQVRTYNYQMGL----------HLANQNQNICIRRETAQCRICWAPTAVIDFAVSGTVAAMGFIVPSSCCGYGAD---GKMVKG--FDCLS-IPGAVSKTLGTKFVSRFCGNNVGLAKVTLVGPDATFCTTNLPFNVRFKSDNYEFLEE----AKLKNK-------GFQLMYEQ 388          

Query:   14 MERFSHLWKMLF-LISFMAFACQCSPIDESRKGLSIFGFVRFQNTACNGTT-RNGTCYTSNECSTRGGLPAGDTCASGYV----TLTCGGTSSENCTYLSKGSDSTSD-CSFTICPKHSNICRIRFDFIVFRISDPVSSITNV-----GGSIGDCTTDSFSITGENG-GSPVICGTNSGRHMIVDSIATCNMAQFFFGGGFN-NXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIP 282
            M  F  L  +LF  +     A +        K L +F  V F N  C G+T RNGTCYTS ECS++GG  +G   +   +    +L CG TSSENCTYL++ S +T+  C + IC   S+ICRIRFDF  F I+ P +  T V     GG++GDC TD FSIT  +G G+PVICG N+G+HMIVD+   C+ A F  G   +   ++D+KVTQF C   +  L GPS CLQYFTG SG I ++ FPT  +   +   ATHLS+Q Y +CIRR +G C ICY+P
Sbjct:    1 MTNFWLLVVILFNFVPLSTLAQKNGTNTREEKLLPLFQIVTFPNDNCAGSTSRNGTCYTSEECSSKGGSSSGSCASGYGICCVFSLGCGSTSSENCTYLTQTSSTTTASCVYNICKCSSDICRIRFDFTTFSIAGPYTGTTGVINIQDGGALGDCLTDQFSITNPSGAGTPVICGFNTGQHMIVDASDGCHKASFSLGSSSSVTRSWDVKVTQFTC---NQDLGGPSDCLQYFTGISGTISSFNFPT--ASTTVPATATHLSNQCYDMCIRRASGYCSICYVP 278          

Query:   40 DESRKG--LSIFGFVRFQNTACNGT-TRNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYLSKGSDSTSDCSFTICPKHSNICRIRFDFIVFRIS-------DPVSSIT---------NVGGSIGDCTTDSFSITGENGGS-PVICGTNSGRHMIVDSIATCN-----MAQFFFGGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSGVIENYAFPT--SISELVIEGKATHLSSQDYRICIRRETGNCRICYIP------TVTGTMSKDSYGLGPSSN-GIEAKSLVNEKCKGDFLEILSGIPFTSTNQMTVGAVNKICGRYFNTADDQIVS-ISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQ 402
            + SR G  +S+F  VRF N  C GT ++NGTCYT++ECST+GG  AG+ CASGY      TL CG +S+ENCTY          C  T+CP   NIC++R DF  F IS       DPVS +T         N   + G C TD+F+ T   G S P ICG N+G HM +DS  +CN     + Q   G G     + IKVTQ+ C +++     P GC QY+ G          PT  ++     +G   HL++Q+  ICIRRE GNCR+CY        +V+G +      +G   N G  A+         D + I      T T +M   A   ICG         ++   ++C+   PF LRF +D  E   E G A             GF L+Y Q
Sbjct:   46 NSSRDGRLVSLFQIVRFPNDPCIGTASKNGTCYTADECSTKGGSSAGN-CASGYGVCCTFTLNCGASSTENCTYFESTGGEVGACRATVCPCSDNICQLRLDFDQFVISGPSTLSVDPVSILTKGQPDPAGANSVTAAGQCLTDTFTATDPGGCSPPSICGINTGEHMYLDSHQSCNDLLFQLGQRGVGAGVATRQWSIKVTQYSCDYKNLA---PDGCTQYYFG----------PTTDTVQTFNYQG-GKHLANQNQNICIRRERGNCRVCYATALDTDFSVSGMVKSMGLTMGKCCNYGSSAEGF-------DCVIIPGARKSTDTAKM---AAVAICGNGMGLVSATMMGPKTICTNRQPFNLRFRSDGYEALMEMGMA-------------GFKLSYIQ 410          

Query:   19 HLWKMLFLISFMAFACQCSPIDESRKGLSIFGFVRFQNTACNGTTRNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYLSKGSDSTSDCSFTICPKHSNICRIRFDFIVFRISDPVS-------------------SITNVGGSIGDCTTDSFSITGENGGS-PVICGTNSGRHMIVDSIATCNMAQFFFGGG------FNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQSG--VIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPTVTGTMSKDSYGL-GPSSNGI-EAKSLVNEKCKGDFLEILSGIPFTSTNQMTVGAVNKICGRYFNTAD-DQIVSISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQ 402
            +L  ++ L+ F+       P+    K  S+F  V+F N  C GT++NGTCY+ NEC+ +GG  +G TCA GY       + C G S+EN TYL  G+ +   C+  ICP+  +IC+ R DF  F ++ P S                   S   V  S   C TD FS++     S P ICG N+G HM VD+   C       G          N  + I+V Q+ C  +D  LA P+GC QYF   SG  V++ Y +          G   HL++Q   +C+RRE G C+IC++      ++ D + + G  + GI    S  N    G+       IP      M     ++ICGR       D   S SVCS   PF +RF++D  E     GD    E +      VGF L Y Q
Sbjct:    3 YLVAIVMLLGFICQRTTGEPLTREGKLFSMFNIVKFANDPCIGTSQNGTCYSPNECTAKGGRSSG-TCAQGYGVCCTFAIACNGQSAENSTYLESGTITPGLCTARICPQSQDICQFRLDFDNFVLTGPSSNTESEYNLAFGQVPPRVPTSNNEVATSRSQCLTDHFSVSNPGSASPPTICGVNTGEHMYVDAPNKCIDLHILIGAAGIFAEIPPNRKWSIQVNQYSC--DDPNLA-PTGCTQYFFDPSGTRVVQTYNYNN--------GNGQHLANQKQTVCVRREKGFCQICWM-----ALADDDFQVSGEETKGITNPSSCCNYGDDGNKGFDCVSIP----GAMLDKPGSRICGRSKGLVSVDDGPSTSVCSQRTPFMIRFISDGYEY----GDGKEGERE------VGFKLQYVQ 391          

Query:   54 FQNTACNGT-TRNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYLSKGSDSTSDCSFTICPKHSNICRIRFDFIVFRISDP-------------VSSIT----NVGG----SIGDCTTDSFSITGENGGS-PVICGTNSGRHMIVDSIATCN-----MAQFFFGGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQ-SGVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIP------TVTGTMSKDSYGLGPSSN-GIEAKSLVNEKCKGDFLEILSGIPFTSTNQMTVGAVNKICGRYFNTADDQIVS-ISVCSFSLPFELRFVTDQDEMTPETGDAVMNENKEEPRGTVGFSLTYKQ 402
            F N AC GT ++NGTCYT++ECS +GG  AGD CASGY      TL CG +S+ENCTY          C   ICP   NIC++R DF  F IS P             V+ +T    +V G    + G C TD+F+ T   G S P ICG N+G HM +DS  +CN     + Q   G G ++  + IKVTQ+ C +++     P GC QY+ G  +  ++ + F              HL++Q+  ICIRRE GNCR+C+        +V+G +      LG   N G   +         D + I      T T +M   A   ICG         ++   ++C+   PF LRF +D  E   E G A             GF L Y Q
Sbjct:  307 FPNDACIGTASKNGTCYTNDECSAKGGNVAGD-CASGYGVCCTFTLNCGASSTENCTYFESTGSEIGACQAKICPCSDNICQLRLDFDQFIISGPSTITDSVTYPNAIVTKLTKGQPDVDGKSVSAAGQCLTDTFTATDPGGCSPPSICGINTGEHMYLDSHESCNDLLFQLGQRGVGAGVSSRQWSIKVTQYSCDYKNLA---PDGCTQYYFGPTTDTVQTFNFQ----------GGKHLANQNQNICIRRERGNCRVCFTTVMDNDFSVSGMLKSMGLTLGKCCNYGTTTEGF-------DCVIIPGARKSTDTAKMAAAA---ICGNGMGLVSVNVMGPKTICTNRQPFNLRFRSDGYEALMEMGMA-------------GFKLVYIQ 660          

Query:   44 KGLSIFGFVRFQNTACNGTT-RNGTCYTSNECSTRGGLPAGDTCASGY-----VTLTCGGTSSENCTYLSKGSDSTSDCSFTICPKHSNICRIRFDFIVFRISDPVSSITNVG--------------GSIGDCTTDSFSITGENG-GSPVICGTNSGRHMIVDSIATCNMAQFFFGG-----GFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQS-GVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICYIPTVTGTMSKDSYG 294
            K LS+F  VRF N  C G   +NGTCYT++ECST+GG     +CA GY      T+ CGG  SENCTY          C  TICP  +NIC++R DF  F I+ P +S+ ++G               +   C TDSFS+    G   P ICG N+  HM VD+   CN   F  G      G  N  + IKVTQ+ C +++     P GC QYF G S   ++ Y F              HL+ Q+  ICIRRE GNCRICY   +    + +  G
Sbjct:   62 KLLSLFQIVRFPNDPCIGNAGKNGTCYTNDECSTKGGSSG-GSCAQGYGVCCTFTVNCGGQRSENCTYFESRGGEVGGCIATICPCSNNICQLRLDFDQFTITGPSTSMASIGTFKFGQPAAAGATYTTSSQCLTDSFSVGDPTGCAPPTICGINTNEHMYVDASEACNDLTFALGNQDLGTGIANRQWSIKVTQYSCDYKNL---APDGCTQYFFGPSTDSVQTYNFD----------GGRHLADQNQNICIRRERGNCRICYTAVLDADFAVNGIG 325          

Query:   52 VRFQNTACNGT-TRNGTCYTSNECSTRGGLPAGDTCASGY--------------------------VTLTCGGTSSENCTYLSKG-SDSTSDCSFTICPKHSNICRIRFDFIVFRISDPVS------------SITNVGGS-----------IGDCTTDSFSIT-GENGGSPVICGTNSGRHMIVDSIATCNMAQFFFGGGFNNXAFDIKVTQFECGFEDTTLAGPSGCLQYFTGQS--GVIENYAFPTSISELVIEGKATHLSSQDYRICIRRETGNCRICY 280
            +RF N ACNGT    GTCYT  EC TR G+  G  CA+GY                          VT++CG TS ENCT  +   +     C+ TICP   NIC++R DF+ F+IS PV+            SI+ + GS           +G C TD F +T G     P ICG NS  HM VD+  +CN   F FGGG  N  F IK+TQ+ C   D+    PSGC QYF  ++  G ++ + F   +          HLS Q+  +C+R+   +CRIC+
Sbjct:  313 IRFPNEACNGTGNVVGTCYTDQECQTRNGMAMG-ACANGYGVCCACKYFNIPVRTWPMYYIHPNVLVTISCGQTSLENCTIFNDNTAPDMGVCTGTICPISPNICQLRLDFMAFQISGPVTDSIQVTDILNGFSISPITGSPPVPRGIPNSAVGQCLTDIFQVTSGSANNPPGICGMNSDEHMFVDADESCNALSFQFGGGNFNREFSIKITQYTC---DSPNLAPSGCTQYFVTENGRGQVQTFNFAGGL----------HLSDQNQVMCVRQNRDSCRICW 581