EMLSAG00000012450, EMLSAG00000012450-695216 (gene) Lepeophtheirus salmonis

Overview
NameEMLSAG00000012450
Unique NameEMLSAG00000012450-695216
Typegene
OrganismLepeophtheirus salmonis (salmon louse)
Associated RNAi Experiments

Nothing found

Homology
BLAST of EMLSAG00000012450 vs. GO
Match: - (symbol:ksr "kinase suppressor of ras" species:7227 "Drosophila melanogaster" [GO:0004672 "protein kinase activity" evidence=ISS;NAS] [GO:0007265 "Ras protein signal transduction" evidence=IGI] [GO:0004674 "protein serine/threonine kinase activity" evidence=ISS;NAS] [GO:0019992 "diacylglycerol binding" evidence=ISS] [GO:0008595 "anterior/posterior axis specification, embryo" evidence=TAS] [GO:0008293 "torso signaling pathway" evidence=NAS] [GO:0006468 "protein phosphorylation" evidence=IEA;NAS] [GO:0005524 "ATP binding" evidence=IEA] [GO:0004713 "protein tyrosine kinase activity" evidence=IEA] [GO:0007426 "tracheal outgrowth, open tracheal system" evidence=IMP] [GO:0007165 "signal transduction" evidence=IDA] [GO:0007476 "imaginal disc-derived wing morphogenesis" evidence=IMP] InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR002219 InterPro:IPR008266 InterPro:IPR011009 InterPro:IPR017441 Pfam:PF00130 Pfam:PF07714 PROSITE:PS00107 PROSITE:PS00109 PROSITE:PS00479 PROSITE:PS50011 PROSITE:PS50081 SMART:SM00109 GO:GO:0005524 GO:GO:0007265 GO:GO:0046872 GO:GO:0008595 GO:GO:0008293 SUPFAM:SSF56112 GO:GO:0018108 GO:GO:0004674 GO:GO:0004672 GO:GO:0004713 GO:GO:0007476 GO:GO:0007426 InterPro:IPR025561 Pfam:PF13543 OrthoDB:EOG7BP81Z EMBL:U43582 ProteinModelPortal:Q24170 SMR:Q24170 PRIDE:Q24170 FlyBase:FBgn0015402 InParanoid:Q24170 Bgee:Q24170 Uniprot:Q24170)

HSP 1 Score: 82.8037 bits (203), Expect = 4.453e-16
Identity = 63/165 (38.18%), Postives = 88/165 (53.33%), Query Frame = 0
Query:   25 LQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSAV----EGIPCLSDLYPNA-----HQWLRVVGLSKEGREAVAQRFTTWAALVSLSDLSI----LDSKALKEDQ--RRLSKALHNLLKFREAFINKGGVYQGD---LYWDSWEVVPSVH 171
            +Q MID+++ HLE LR  C A+SS LT++EIR LE KL++ F     A     E IP  + L P+       QWLRVVGLS+    A   R TT    + LSD  I     DS + +E++  RRL++A+ NL K  E+  +       D    +WDSW+    +H
Sbjct:   36 IQDMIDLSANHLEGLRTQC-AISSTLTQQEIRCLESKLVRYFSELLLAKMRLNERIPA-NGLVPHTTGNELRQWLRVVGLSQGTLTACLARLTTLEQSLRLSDEEIRQLLADSPSQREEEELRRLTRAMQNLRKCMESLESGTAASNNDPEQWHWDSWDRPTHIH 198          
BLAST of EMLSAG00000012450 vs. GO
Match: - (symbol:KSR1 "Uncharacterized protein" species:9031 "Gallus gallus" [GO:0004674 "protein serine/threonine kinase activity" evidence=IEA] [GO:0005078 "MAP-kinase scaffold activity" evidence=IEA] [GO:0005524 "ATP binding" evidence=IEA] [GO:0035556 "intracellular signal transduction" evidence=IEA] [GO:0043410 "positive regulation of MAPK cascade" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR002219 InterPro:IPR008271 InterPro:IPR011009 Pfam:PF07714 PROSITE:PS00108 PROSITE:PS00479 PROSITE:PS50011 PROSITE:PS50081 SMART:SM00109 GO:GO:0005524 GO:GO:0035556 GO:GO:0046872 SUPFAM:SSF56112 GO:GO:0004674 GO:GO:0043410 TreeFam:TF317006 GeneTree:ENSGT00740000115100 InterPro:IPR025561 Pfam:PF13543 OMA:EVSPMRF OrthoDB:EOG7BP81Z EMBL:AADN03007725 Ensembl:ENSGALT00000009118 PRO:PR:E1C7R3 Uniprot:E1C7R3)

HSP 1 Score: 73.1738 bits (178), Expect = 8.132e-13
Identity = 91/314 (28.98%), Postives = 136/314 (43.31%), Query Frame = 0
Query:   22 CGELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSAVEGIPCLSDL------YPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSDLSILDSK----ALKEDQRRLSKALHNLLKFREAFINKGGVYQGDLYWDSWEVV---PSVHTEEEHSSS------SSSSIP------------SVLPKGDSAASS---------------LSSTSGSIPPPSPGPLTLSPPVIGWDRKPTPPTTPPWSTSSLLCGTAYNKMNNAASSTTKQFPSVSSSSSENHSLVKSQSHESELASRIDIV 289
            CG LQ +ID++  +L  LR  C+A S++LT++EIRTLE KLI    RQ      +P L+D       YP  + WL +V + KE  + + +  T   AL+ +++  + ++     A  E+  RL+ AL  L K  E+    GG  + D+  +  EV     S +  E   SS      S+ S+P            S +P  DS ASS                 + SG + P +P  +T+           TPPTTP       L                +  PS         +L +S+SHES+L +RID V
Sbjct:   40 CGLLQDLIDISLSNLRGLRTKCAA-SNDLTQQEIRTLEVKLIDYIHRQRQCKLSVP-LNDRTAELNSYPRFNDWLDIVNVRKEVVQRIPEELTL-DALLEMNESKVKETMKRCGARDEECSRLNGALSCLRKVTES----GGELKDDVLTNLSEVRRENSSTNMTESPCSSAPTWTHSALSLPKGNSQQARSVSVSTIPSSDSLASSHGPSIYADNLLDPFAFPAHSGRLTPRTPHSITV-----------TPPTTPQAKRRHKL--KPPRTPPPPCRKVFQLLPSFP-------TLTRSKSHESQLGNRIDDV 326          
BLAST of EMLSAG00000012450 vs. GO
Match: - (symbol:KSR2 "Kinase suppressor of Ras 2" species:9606 "Homo sapiens" [GO:0004674 "protein serine/threonine kinase activity" evidence=IEA] [GO:0005078 "MAP-kinase scaffold activity" evidence=IEA] [GO:0005524 "ATP binding" evidence=IEA] [GO:0005829 "cytosol" evidence=IEA] [GO:0005886 "plasma membrane" evidence=IEA] [GO:0019722 "calcium-mediated signaling" evidence=IEA] [GO:0031434 "mitogen-activated protein kinase kinase binding" evidence=IEA] [GO:0043410 "positive regulation of MAPK cascade" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR002219 InterPro:IPR008271 InterPro:IPR011009 Pfam:PF07714 PROSITE:PS00108 PROSITE:PS00479 PROSITE:PS50011 PROSITE:PS50081 SMART:SM00109 GO:GO:0005829 GO:GO:0005886 GO:GO:0005524 GO:GO:0046872 eggNOG:COG0515 GO:GO:0019722 SUPFAM:SSF56112 GO:GO:0004674 GO:GO:0043410 TreeFam:TF317006 CleanEx:HS_KSR2 HOGENOM:HOG000113263 HOVERGEN:HBG052293 InterPro:IPR025561 Pfam:PF13543 OrthoDB:EOG7BP81Z EMBL:AK098831 EMBL:AC073864 EMBL:AC079127 EMBL:AC084291 EMBL:AC092936 EMBL:AY345972 EMBL:BC107106 EMBL:BC107107 EMBL:BC127603 RefSeq:NP_775869.3 UniGene:Hs.375836 PDB:2Y4I PDBsum:2Y4I ProteinModelPortal:Q6VAB6 SMR:Q6VAB6 BioGrid:129567 DIP:DIP-59195N IntAct:Q6VAB6 MINT:MINT-8397064 STRING:9606.ENSP00000339952 PhosphoSite:Q6VAB6 DMDM:148886599 PaxDb:Q6VAB6 PRIDE:Q6VAB6 Ensembl:ENST00000339824 GeneID:283455 KEGG:hsa:283455 UCSC:uc001two.2 CTD:283455 GeneCards:GC12M117890 H-InvDB:HIX0018992 HGNC:HGNC:18610 HPA:HPA035536 MIM:610737 neXtProt:NX_Q6VAB6 PharmGKB:PA134914125 InParanoid:Q6VAB6 OMA:KCIQHYC SignaLink:Q6VAB6 ChiTaRS:KSR2 GenomeRNAi:283455 NextBio:93924 PRO:PR:Q6VAB6 ArrayExpress:Q6VAB6 Bgee:Q6VAB6 Genevestigator:Q6VAB6 Uniprot:Q6VAB6)

HSP 1 Score: 65.4698 bits (158), Expect = 2.964e-10
Identity = 47/155 (30.32%), Postives = 81/155 (52.26%), Query Frame = 0
Query:   22 CGELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSAVEGIPCLS-----DLYPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSDLSILDS----KALKEDQRRLSKALHNLLKFREAFINKGGVYQGD--LYWDSWE 165
            C  +Q MID++  +LE LR  C A S++LT++EIRTLE KL++ F RQ S  + +         D +P    W R+V + KE  E ++    +   L+ ++D  + ++     A +E+  RL+ +L  L   R   ++ G + + D  + W + E
Sbjct:   24 CELVQNMIDLSISNLEGLRTKC-ATSNDLTQKEIRTLESKLVKYFSRQLSCKKKVALQERNAELDGFPQLRHWFRIVDVRKEVLEEISPGQLSLEDLLEMTDEQVCETVEKYGANREECARLNASLSCL---RNVHMSGGNLSKQDWTIQWPTTE 174          
BLAST of EMLSAG00000012450 vs. GO
Match: - (symbol:Ksr2 "kinase suppressor of ras 2" species:10090 "Mus musculus" [GO:0000166 "nucleotide binding" evidence=IEA] [GO:0004672 "protein kinase activity" evidence=IEA] [GO:0004674 "protein serine/threonine kinase activity" evidence=IEA] [GO:0005078 "MAP-kinase scaffold activity" evidence=IDA] [GO:0005515 "protein binding" evidence=IPI] [GO:0005524 "ATP binding" evidence=IEA] [GO:0005622 "intracellular" evidence=IGI] [GO:0005737 "cytoplasm" evidence=IEA] [GO:0005829 "cytosol" evidence=IDA] [GO:0005886 "plasma membrane" evidence=IDA] [GO:0006468 "protein phosphorylation" evidence=IEA] [GO:0016020 "membrane" evidence=IEA] [GO:0016301 "kinase activity" evidence=IEA] [GO:0016310 "phosphorylation" evidence=IEA] [GO:0016740 "transferase activity" evidence=IEA] [GO:0016772 "transferase activity, transferring phosphorus-containing groups" evidence=IEA] [GO:0019722 "calcium-mediated signaling" evidence=IGI] [GO:0031434 "mitogen-activated protein kinase kinase binding" evidence=IDA] [GO:0035556 "intracellular signal transduction" evidence=IEA] [GO:0043410 "positive regulation of MAPK cascade" evidence=IDA] [GO:0046872 "metal ion binding" evidence=IEA] InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR002219 InterPro:IPR008271 InterPro:IPR011009 Pfam:PF07714 PROSITE:PS00108 PROSITE:PS00479 PROSITE:PS50011 PROSITE:PS50081 SMART:SM00109 MGI:MGI:3610315 GO:GO:0005829 GO:GO:0005886 GO:GO:0005524 GO:GO:0046872 GO:GO:0019722 SUPFAM:SSF56112 GO:GO:0004674 GO:GO:0043410 GO:GO:0031434 GO:GO:0005078 HOVERGEN:HBG052293 InterPro:IPR025561 Pfam:PF13543 EMBL:AC113299 EMBL:AC113303 EMBL:AC114617 EMBL:AK137433 UniGene:Mm.437947 ProteinModelPortal:Q3UVC0 SMR:Q3UVC0 PhosphoSite:Q3UVC0 PaxDb:Q3UVC0 PRIDE:Q3UVC0 UCSC:uc008zfw.2 eggNOG:KOG0193 HOGENOM:HOG000110293 InParanoid:Q3UVC0 NextBio:13857732 PRO:PR:Q3UVC0 Bgee:Q3UVC0 CleanEx:MM_KSR2 Genevestigator:Q3UVC0 Uniprot:Q3UVC0)

HSP 1 Score: 65.0846 bits (157), Expect = 3.137e-10
Identity = 42/129 (32.56%), Postives = 71/129 (55.04%), Query Frame = 0
Query:   22 CGELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSAVEGIPCLS-----DLYPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSDLSILDS----KALKEDQRRLSKALHNL 141
            C  +Q MID++  +LE LR  C+A S++LT++EIRTLE KL++ F RQ S  + +         D +P    W R+V + KE  E ++    +   L+ ++D  + ++     A +E+  RL+ +L  L
Sbjct:   24 CELVQNMIDLSISNLEGLRTKCAA-SNDLTQKEIRTLESKLVKYFSRQLSCKKKVALQERNAELDGFPQLRHWFRIVDVRKEVLEEISPDQLSLEDLLEMTDEQVCETVEKYGANQEECARLNASLSCL 151          
BLAST of EMLSAG00000012450 vs. GO
Match: - (symbol:KSR2 "Uncharacterized protein" species:9913 "Bos taurus" [GO:0004674 "protein serine/threonine kinase activity" evidence=IEA] [GO:0005078 "MAP-kinase scaffold activity" evidence=IEA] [GO:0005524 "ATP binding" evidence=IEA] [GO:0005829 "cytosol" evidence=IEA] [GO:0005886 "plasma membrane" evidence=IEA] [GO:0019722 "calcium-mediated signaling" evidence=IEA] [GO:0031434 "mitogen-activated protein kinase kinase binding" evidence=IEA] [GO:0043410 "positive regulation of MAPK cascade" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR002219 InterPro:IPR008271 InterPro:IPR011009 Pfam:PF07714 PROSITE:PS00108 PROSITE:PS00479 PROSITE:PS50011 PROSITE:PS50081 SMART:SM00109 GO:GO:0005829 GO:GO:0005886 GO:GO:0005524 GO:GO:0046872 GO:GO:0019722 SUPFAM:SSF56112 GO:GO:0004674 GO:GO:0043410 TreeFam:TF317006 GeneTree:ENSGT00740000115100 InterPro:IPR025561 Pfam:PF13543 OrthoDB:EOG7BP81Z CTD:283455 OMA:KCIQHYC EMBL:DAAA02045334 EMBL:DAAA02045335 EMBL:DAAA02045336 EMBL:DAAA02045337 EMBL:DAAA02045338 EMBL:DAAA02045339 EMBL:DAAA02045340 EMBL:DAAA02045341 EMBL:DAAA02045342 EMBL:DAAA02045343 RefSeq:NP_001193791.1 RefSeq:XP_005217993.1 UniGene:Bt.112348 Ensembl:ENSBTAT00000061442 GeneID:617325 KEGG:bta:617325 NextBio:20900602 Uniprot:F1MF36)

HSP 1 Score: 65.0846 bits (157), Expect = 3.614e-10
Identity = 47/155 (30.32%), Postives = 80/155 (51.61%), Query Frame = 0
Query:   22 CGELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSAVEGIPCLS-----DLYPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSDLSILDS----KALKEDQRRLSKALHNLLKFREAFINKGGVYQGD--LYWDSWE 165
            C  +Q MID++  +LE LR  C A S++LT++EIRTLE KL++ F RQ S  + +         D +P    W R+V + KE  E +     +   L+ ++D  + ++     A +E+  RL+ +L  L   R   ++ G + + D  + W + E
Sbjct:   24 CELVQNMIDLSISNLEGLRTKC-ATSNDLTQKEIRTLESKLVKYFSRQLSCKKKVALQERNAELDGFPQLRHWFRIVDVRKEVLEEITPGQLSLEDLLEMTDEQVCETVEKYGANREECARLNASLSCL---RNVHMSGGNLSKQDWTIQWPTTE 174          
BLAST of EMLSAG00000012450 vs. GO
Match: - (symbol:KSR2 "Uncharacterized protein" species:9615 "Canis lupus familiaris" [GO:0004674 "protein serine/threonine kinase activity" evidence=IEA] [GO:0005078 "MAP-kinase scaffold activity" evidence=IEA] [GO:0005524 "ATP binding" evidence=IEA] [GO:0005829 "cytosol" evidence=IEA] [GO:0005886 "plasma membrane" evidence=IEA] [GO:0019722 "calcium-mediated signaling" evidence=IEA] [GO:0031434 "mitogen-activated protein kinase kinase binding" evidence=IEA] [GO:0043410 "positive regulation of MAPK cascade" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR002219 InterPro:IPR008271 InterPro:IPR011009 Pfam:PF07714 PROSITE:PS00108 PROSITE:PS00479 PROSITE:PS50011 PROSITE:PS50081 SMART:SM00109 GO:GO:0005829 GO:GO:0005886 GO:GO:0005524 GO:GO:0046872 GO:GO:0019722 SUPFAM:SSF56112 GO:GO:0004674 GO:GO:0043410 TreeFam:TF317006 GeneTree:ENSGT00740000115100 InterPro:IPR025561 Pfam:PF13543 OrthoDB:EOG7BP81Z CTD:283455 OMA:KCIQHYC EMBL:AAEX03014716 EMBL:AAEX03014717 EMBL:AAEX03014718 RefSeq:XP_543417.3 Ensembl:ENSCAFT00000015680 GeneID:486291 KEGG:cfa:486291 Uniprot:F1P721)

HSP 1 Score: 65.0846 bits (157), Expect = 3.955e-10
Identity = 47/155 (30.32%), Postives = 80/155 (51.61%), Query Frame = 0
Query:   22 CGELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSAVEGIPCLS-----DLYPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSDLSILDS----KALKEDQRRLSKALHNLLKFREAFINKGGVYQGD--LYWDSWE 165
            C  +Q MID++  +LE LR  C A S++LT++EIRTLE KL++ F RQ S  + +         D +P    W R+V + KE  E +     +   L+ ++D  + ++     A +E+  RL+ +L  L   R   ++ G + + D  + W + E
Sbjct:   24 CELVQNMIDLSISNLEGLRTKC-ATSNDLTQKEIRTLESKLVKYFSRQLSCKKKVALQERNAELDGFPQLRHWFRIVDVRKEVLEEITPGQLSLEDLLEMTDEQVCETVEKYGANREECARLNASLSCL---RNVHMSGGNLSKQDWTIQWPTTE 174          
BLAST of EMLSAG00000012450 vs. GO
Match: - (symbol:Ksr1 "kinase suppressor of ras 1" species:10090 "Mus musculus" [GO:0004672 "protein kinase activity" evidence=IEA] [GO:0004674 "protein serine/threonine kinase activity" evidence=IEA] [GO:0005078 "MAP-kinase scaffold activity" evidence=IDA] [GO:0005515 "protein binding" evidence=IPI] [GO:0005524 "ATP binding" evidence=IEA] [GO:0005737 "cytoplasm" evidence=IEA] [GO:0005783 "endoplasmic reticulum" evidence=IEA] [GO:0006468 "protein phosphorylation" evidence=IEA] [GO:0016020 "membrane" evidence=IEA] [GO:0016772 "transferase activity, transferring phosphorus-containing groups" evidence=IEA] [GO:0031434 "mitogen-activated protein kinase kinase binding" evidence=ISO] [GO:0035556 "intracellular signal transduction" evidence=IEA] [GO:0043410 "positive regulation of MAPK cascade" evidence=IDA] [GO:0046872 "metal ion binding" evidence=IEA] InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR002219 InterPro:IPR008271 InterPro:IPR011009 Pfam:PF07714 PROSITE:PS00108 PROSITE:PS00479 PROSITE:PS50011 PROSITE:PS50081 SMART:SM00109 MGI:MGI:105051 GO:GO:0005524 GO:GO:0005789 GO:GO:0035556 GO:GO:0046872 eggNOG:COG0515 SUPFAM:SSF56112 GO:GO:0004674 GO:GO:0043410 TreeFam:TF317006 GeneTree:ENSGT00740000115100 GO:GO:0005078 CTD:8844 HOGENOM:HOG000113263 HOVERGEN:HBG052293 KO:K14958 InterPro:IPR025561 Pfam:PF13543 EMBL:U43585 EMBL:AL592551 EMBL:X81634 PIR:I48379 RefSeq:NP_038599.1 RefSeq:XP_006532398.1 UniGene:Mm.4745 PDB:1KBE PDB:1KBF PDB:2LPE PDBsum:1KBE PDBsum:1KBF PDBsum:2LPE ProteinModelPortal:Q61097 SMR:Q61097 BioGrid:201048 IntAct:Q61097 MINT:MINT-99547 PhosphoSite:Q61097 PaxDb:Q61097 PRIDE:Q61097 DNASU:16706 Ensembl:ENSMUST00000018478 GeneID:16706 KEGG:mmu:16706 UCSC:uc007kkg.1 InParanoid:Q61097 OMA:EVSPMRF OrthoDB:EOG7BP81Z EvolutionaryTrace:Q61097 NextBio:290486 PRO:PR:Q61097 ArrayExpress:Q61097 Bgee:Q61097 CleanEx:MM_KSR1 Genevestigator:Q61097 Uniprot:Q61097)

HSP 1 Score: 64.3142 bits (155), Expect = 5.389e-10
Identity = 81/292 (27.74%), Postives = 123/292 (42.12%), Query Frame = 0
Query:   22 CGELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGR-QWSAVEGIPC--LSDL--YPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSDLSILDSKALKEDQRRLSKALHNLLKFREAF------INKGGVYQGDLYWDS-----------WEVVPSVHTEEEHSSSSSSSIPSVLPKGDSAASSLSS--TSGSIPPPSPGPLTLSPPVIGWDRKPTPPTTPPWSTSSLLCGTAYNKMNNAASSTTKQFPSVSSSSSENHSLVKSQSHESELASRIDIV 289
            CG+LQ +ID++   L  LR  CS +S++LT++EIRTLE KL++   + Q S +   P    ++L  YP    WL +  +  E  + + Q  T       L  L  +D    KE  RR   +     + ++A          GG ++ D  W S            +++ S+      +    S   S LP  DS    LS   +   IP  + G LT  P  +      TPPTTP     + L           +    +  PS         +L +S+SHES+L +RID V
Sbjct:   39 CGQLQKLIDISIGSLRGLRTKCS-VSNDLTQQEIRTLEAKLVKYICKQQQSKLSVTPSDRTAELNSYPRFSDWLYIFNVRPEVVQEIPQELT-------LDALLEMDEAKAKEMLRRWGASTEECSRLQQALTCLRKVTGLGGEHKMDSGWSSTDARDSSLGPPMDMLSSLGRAGASTQGPRSISVSALPASDSPVPGLSEGLSDSCIPLHTSGRLT--PRAL--HSFITPPTTPQLRRHAKL--KPPRTPPPPSRKVFQLLPSFP-------TLTRSKSHESQLGNRIDDV 309          
BLAST of EMLSAG00000012450 vs. GO
Match: - (symbol:KSR1 "Kinase suppressor of Ras 1" species:9606 "Homo sapiens" [GO:0004674 "protein serine/threonine kinase activity" evidence=IEA] [GO:0005524 "ATP binding" evidence=IEA] [GO:0035556 "intracellular signal transduction" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR002219 InterPro:IPR008271 InterPro:IPR011009 Pfam:PF07714 PROSITE:PS00108 PROSITE:PS00479 PROSITE:PS50011 PROSITE:PS50081 SMART:SM00109 GO:GO:0005524 GO:GO:0035556 GO:GO:0046872 SUPFAM:SSF56112 GO:GO:0004674 EMBL:AC069366 EMBL:AC015688 HGNC:HGNC:6465 ChiTaRS:KSR1 InterPro:IPR025561 Pfam:PF13543 ProteinModelPortal:F5H0K8 SMR:F5H0K8 PRIDE:F5H0K8 Ensembl:ENST00000509603 NextBio:35508041 ArrayExpress:F5H0K8 Bgee:F5H0K8 Uniprot:F5H0K8)

HSP 1 Score: 62.7734 bits (151), Expect = 2.076e-9
Identity = 85/303 (28.05%), Postives = 128/303 (42.24%), Query Frame = 0
Query:   22 CGELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSAV------EGIPCLSDLYPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSDLSILDS----KALKEDQRRLSKALHNLLKFREAFINKGGVYQGDLYWDSWEVVPSVHTEEEHSSSSSSSIP-----------------------SVLPKGDSAASSLSS--TSGSIPPPSPGPLTLSPPVIGWDRKPTPPTTPPWSTSSLLCGTAYNKMNNAASSTTKQFPSVSSSSSENHSLVKSQSHESELASRIDIV 289
            CG+LQ +ID++   L  LR  C A+S++LT++EIRTLE KL++   +Q          E  P L+  YP    WL    +  E  + +  R  T  AL+ +++  + ++     A  ++  RL  AL  L K        GG ++ D  W S +      +     + S++S+P                       S LP  DS   S S   +   IP  + G LT  P  +      TPPTTP      L   T           + K F  + S      +L +S+SHES+L +RID V
Sbjct:   41 CGQLQKLIDISIGSLRGLRTKC-AVSNDLTQQEIRTLEAKLVRYICKQRQCKLSVAPGERTPELNS-YPRFSDWLYTFNVRPEVVQEIP-RDLTLDALLEMNEAKVKETLRRCGASGDECGRLQYALTCLRK----VTGLGGEHKEDSSWSSLDARRESGSGPSTDTLSAASLPWPPGSSQLGRAGNSAQGPRSISVSALPASDSPTPSFSEGLSDTCIPLHASGRLT--PRAL--HSFITPPTTP-----QLRRHTKLKPPRTPPPPSRKVFQLLPSFP----TLTRSKSHESQLGNRIDDV 323          
BLAST of EMLSAG00000012450 vs. GO
Match: - (symbol:KSR1 "Kinase suppressor of Ras 1" species:9606 "Homo sapiens" [GO:0004672 "protein kinase activity" evidence=NAS] [GO:0004674 "protein serine/threonine kinase activity" evidence=IEA] [GO:0005515 "protein binding" evidence=IPI] [GO:0005524 "ATP binding" evidence=IEA] [GO:0005789 "endoplasmic reticulum membrane" evidence=IEA] [GO:0007265 "Ras protein signal transduction" evidence=NAS] [GO:0046872 "metal ion binding" evidence=IEA] InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR002219 InterPro:IPR008271 InterPro:IPR011009 Pfam:PF07714 PROSITE:PS00108 PROSITE:PS00479 PROSITE:PS50011 PROSITE:PS50081 SMART:SM00109 EMBL:U43586 GO:GO:0005524 GO:GO:0007265 GO:GO:0005789 GO:GO:0046872 eggNOG:COG0515 SUPFAM:SSF56112 GO:GO:0004674 GO:GO:0004672 EMBL:AC069366 EMBL:AC015688 EMBL:BC042106 RefSeq:NP_055053.1 UniGene:Hs.133534 ProteinModelPortal:Q8IVT5 SMR:Q8IVT5 BioGrid:114371 IntAct:Q8IVT5 MINT:MINT-87143 STRING:9606.ENSP00000268763 PhosphoSite:Q8IVT5 DMDM:56749095 PaxDb:Q8IVT5 PRIDE:Q8IVT5 DNASU:8844 Ensembl:ENST00000268763 GeneID:8844 KEGG:hsa:8844 CTD:8844 GeneCards:GC17P025783 H-InvDB:HIX0018394 H-InvDB:HIX0025516 H-InvDB:HIX0029273 HGNC:HGNC:6465 HPA:CAB009623 HPA:HPA011215 MIM:601132 neXtProt:NX_Q8IVT5 PharmGKB:PA30254 HOGENOM:HOG000113263 HOVERGEN:HBG052293 InParanoid:Q8IVT5 KO:K14958 SignaLink:Q8IVT5 ChiTaRS:KSR1 GeneWiki:KSR1 GenomeRNAi:8844 NextBio:33204 PRO:PR:Q8IVT5 ArrayExpress:Q8IVT5 Bgee:Q8IVT5 CleanEx:HS_KSR1 Genevestigator:Q8IVT5 InterPro:IPR025561 Pfam:PF13543 Uniprot:Q8IVT5)

HSP 1 Score: 62.3882 bits (150), Expect = 2.302e-9
Identity = 85/303 (28.05%), Postives = 128/303 (42.24%), Query Frame = 0
Query:   22 CGELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSAV------EGIPCLSDLYPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSDLSILDS----KALKEDQRRLSKALHNLLKFREAFINKGGVYQGDLYWDSWEVVPSVHTEEEHSSSSSSSIP-----------------------SVLPKGDSAASSLSS--TSGSIPPPSPGPLTLSPPVIGWDRKPTPPTTPPWSTSSLLCGTAYNKMNNAASSTTKQFPSVSSSSSENHSLVKSQSHESELASRIDIV 289
            CG+LQ +ID++   L  LR  C A+S++LT++EIRTLE KL++   +Q          E  P L+  YP    WL    +  E  + +  R  T  AL+ +++  + ++     A  ++  RL  AL  L K        GG ++ D  W S +      +     + S++S+P                       S LP  DS   S S   +   IP  + G LT  P  +      TPPTTP      L   T           + K F  + S      +L +S+SHES+L +RID V
Sbjct:   39 CGQLQKLIDISIGSLRGLRTKC-AVSNDLTQQEIRTLEAKLVRYICKQRQCKLSVAPGERTPELNS-YPRFSDWLYTFNVRPEVVQEIP-RDLTLDALLEMNEAKVKETLRRCGASGDECGRLQYALTCLRK----VTGLGGEHKEDSSWSSLDARRESGSGPSTDTLSAASLPWPPGSSQLGRAGNSAQGPRSISVSALPASDSPTPSFSEGLSDTCIPLHASGRLT--PRAL--HSFITPPTTP-----QLRRHTKLKPPRTPPPPSRKVFQLLPSFP----TLTRSKSHESQLGNRIDDV 321          
BLAST of EMLSAG00000012450 vs. GO
Match: - (symbol:KSR1 "Kinase suppressor of Ras 1" species:9606 "Homo sapiens" [GO:0004674 "protein serine/threonine kinase activity" evidence=IEA] [GO:0005524 "ATP binding" evidence=IEA] [GO:0035556 "intracellular signal transduction" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR002219 InterPro:IPR008271 InterPro:IPR011009 Pfam:PF07714 PROSITE:PS00108 PROSITE:PS00479 PROSITE:PS50011 PROSITE:PS50081 SMART:SM00109 GO:GO:0005524 GO:GO:0035556 GO:GO:0046872 SUPFAM:SSF56112 GO:GO:0004674 TreeFam:TF317006 EMBL:AC069366 EMBL:AC015688 HGNC:HGNC:6465 ChiTaRS:KSR1 InterPro:IPR025561 Pfam:PF13543 OMA:EVSPMRF ProteinModelPortal:F8WEA9 SMR:F8WEA9 PRIDE:F8WEA9 Ensembl:ENST00000319524 NextBio:35514308 ArrayExpress:F8WEA9 Bgee:F8WEA9 Uniprot:F8WEA9)

HSP 1 Score: 62.3882 bits (150), Expect = 2.497e-9
Identity = 85/303 (28.05%), Postives = 128/303 (42.24%), Query Frame = 0
Query:   22 CGELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSAV------EGIPCLSDLYPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSDLSILDS----KALKEDQRRLSKALHNLLKFREAFINKGGVYQGDLYWDSWEVVPSVHTEEEHSSSSSSSIP-----------------------SVLPKGDSAASSLSS--TSGSIPPPSPGPLTLSPPVIGWDRKPTPPTTPPWSTSSLLCGTAYNKMNNAASSTTKQFPSVSSSSSENHSLVKSQSHESELASRIDIV 289
            CG+LQ +ID++   L  LR  C A+S++LT++EIRTLE KL++   +Q          E  P L+  YP    WL    +  E  + +  R  T  AL+ +++  + ++     A  ++  RL  AL  L K        GG ++ D  W S +      +     + S++S+P                       S LP  DS   S S   +   IP  + G LT  P  +      TPPTTP      L   T           + K F  + S      +L +S+SHES+L +RID V
Sbjct:   41 CGQLQKLIDISIGSLRGLRTKC-AVSNDLTQQEIRTLEAKLVRYICKQRQCKLSVAPGERTPELNS-YPRFSDWLYTFNVRPEVVQEIP-RDLTLDALLEMNEAKVKETLRRCGASGDECGRLQYALTCLRK----VTGLGGEHKEDSSWSSLDARRESGSGPSTDTLSAASLPWPPGSSQLGRAGNSAQGPRSISVSALPASDSPTPSFSEGLSDTCIPLHASGRLT--PRAL--HSFITPPTTP-----QLRRHTKLKPPRTPPPPSRKVFQLLPSFP----TLTRSKSHESQLGNRIDDV 323          
BLAST of EMLSAG00000012450 vs. C. finmarchicus
Match: gi|592822342|gb|GAXK01132226.1| (TSA: Calanus finmarchicus comp26594_c0_seq2 transcribed RNA sequence)

HSP 1 Score: 91.6633 bits (226), Expect = 2.552e-19
Identity = 60/162 (37.04%), Postives = 89/162 (54.94%), Query Frame = 0
Query:   22 CGELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSAVEGI-PCLSDL--YPNAHQWLRVVGLSKEGREAVAQRFTTWXXXXXXX---------XXXXXXXXXXXEDQRRLSKALHNLLKFREAFINKGGVY-------QGDLYWDSW 164
            C ++Q MID+ S+HL+ LR+T S    ELT +EIRTLEGKLI+ F  Q +   G+    SDL  +P+  QWL+VVG+S +  +A+  R  +   L   +           S +     +ED RRL ++L NL K+ +A +    VY       + +L+WDSW
Sbjct: 2434 CQDVQHMIDITSDHLDRLRSTFSNAGDELTMQEIRTLEGKLIKQFSEQLAVKTGLGASASDLVYFPSLSQWLKVVGVSSDTNDAIRSRVRSLEELKDKTECELRRILLTASRVSPVQRQEDLRRLCRSLLNLRKYTDALVYGHKVYGPSQDPAKLELHWDSW 2919          
BLAST of EMLSAG00000012450 vs. C. finmarchicus
Match: gi|592822343|gb|GAXK01132225.1| (TSA: Calanus finmarchicus comp26594_c0_seq1 transcribed RNA sequence)

HSP 1 Score: 91.6633 bits (226), Expect = 2.569e-19
Identity = 60/162 (37.04%), Postives = 89/162 (54.94%), Query Frame = 0
Query:   22 CGELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSAVEGI-PCLSDL--YPNAHQWLRVVGLSKEGREAVAQRFTTWXXXXXXX---------XXXXXXXXXXXEDQRRLSKALHNLLKFREAFINKGGVY-------QGDLYWDSW 164
            C ++Q MID+ S+HL+ LR+T S    ELT +EIRTLEGKLI+ F  Q +   G+    SDL  +P+  QWL+VVG+S +  +A+  R  +   L   +           S +     +ED RRL ++L NL K+ +A +    VY       + +L+WDSW
Sbjct: 2434 CQDVQHMIDITSDHLDRLRSTFSNAGDELTMQEIRTLEGKLIKQFSEQLAVKTGLGASASDLVYFPSLSQWLKVVGVSSDTNDAIRSRVRSLEELKDKTECELRRILLTASRVSPVQRQEDLRRLCRSLLNLRKYTDALVYGHKVYGPSQDPAKLELHWDSW 2919          
BLAST of EMLSAG00000012450 vs. L. salmonis peptides
Match: EMLSAP00000012450 (pep:novel supercontig:LSalAtl2s:LSalAtl2s9156:540:1591:-1 gene:EMLSAG00000012450 transcript:EMLSAT00000012450 description:"maker-LSalAtl2s9156-snap-gene-0.3")

HSP 1 Score: 679.863 bits (1753), Expect = 0.000e+0
Identity = 334/334 (100.00%), Postives = 334/334 (100.00%), Query Frame = 0
Query:    1 MRTMECEEDEEGSLLRHRRCTCGELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSAVEGIPCLSDLYPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSDLSILDSKALKEDQRRLSKALHNLLKFREAFINKGGVYQGDLYWDSWEVVPSVHTEEEHSSSSSSSIPSVLPKGDSAASSLSSTSGSIPPPSPGPLTLSPPVIGWDRKPTPPTTPPWSTSSLLCGTAYNKMNNAASSTTKQFPSVSSSSSENHSLVKSQSHESELASRIDIVDLGXGHSTVIHYQHHSYSSNTHFKQQQRLGRPRLATEPSILPTDE 334
            MRTMECEEDEEGSLLRHRRCTCGELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSAVEGIPCLSDLYPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSDLSILDSKALKEDQRRLSKALHNLLKFREAFINKGGVYQGDLYWDSWEVVPSVHTEEEHSSSSSSSIPSVLPKGDSAASSLSSTSGSIPPPSPGPLTLSPPVIGWDRKPTPPTTPPWSTSSLLCGTAYNKMNNAASSTTKQFPSVSSSSSENHSLVKSQSHESELASRIDIVDLGXGHSTVIHYQHHSYSSNTHFKQQQRLGRPRLATEPSILPTDE
Sbjct:    1 MRTMECEEDEEGSLLRHRRCTCGELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSAVEGIPCLSDLYPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSDLSILDSKALKEDQRRLSKALHNLLKFREAFINKGGVYQGDLYWDSWEVVPSVHTEEEHSSSSSSSIPSVLPKGDSAASSLSSTSGSIPPPSPGPLTLSPPVIGWDRKPTPPTTPPWSTSSLLCGTAYNKMNNAASSTTKQFPSVSSSSSENHSLVKSQSHESELASRIDIVDLGXGHSTVIHYQHHSYSSNTHFKQQQRLGRPRLATEPSILPTDE 334          
BLAST of EMLSAG00000012450 vs. SwissProt
Match: gi|148886599|sp|Q6VAB6.2|KSR2_HUMAN (RecName: Full=Kinase suppressor of Ras 2; Short=hKSR2)

HSP 1 Score: 65.4698 bits (158), Expect = 2.162e-10
Identity = 47/155 (30.32%), Postives = 81/155 (52.26%), Query Frame = 0
Query:   22 CGELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSAVEGIPCLS-----DLYPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSDLSILDS----KALKEDQRRLSKALHNLLKFREAFINKGGVYQGD--LYWDSWE 165
            C  +Q MID++  +LE LR  C A S++LT++EIRTLE KL++ F RQ S  + +         D +P    W R+V + KE  E ++    +   L+ ++D  + ++     A +E+  RL+ +L  L   R   ++ G + + D  + W + E
Sbjct:   24 CELVQNMIDLSISNLEGLRTKC-ATSNDLTQKEIRTLESKLVKYFSRQLSCKKKVALQERNAELDGFPQLRHWFRIVDVRKEVLEEISPGQLSLEDLLEMTDEQVCETVEKYGANREECARLNASLSCL---RNVHMSGGNLSKQDWTIQWPTTE 174          
BLAST of EMLSAG00000012450 vs. SwissProt
Match: gi|147647674|sp|Q3UVC0.2|KSR2_MOUSE (RecName: Full=Kinase suppressor of Ras 2)

HSP 1 Score: 65.0846 bits (157), Expect = 2.288e-10
Identity = 42/129 (32.56%), Postives = 71/129 (55.04%), Query Frame = 0
Query:   22 CGELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSAVEGIPCLS-----DLYPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSDLSILDS----KALKEDQRRLSKALHNL 141
            C  +Q MID++  +LE LR  C+A S++LT++EIRTLE KL++ F RQ S  + +         D +P    W R+V + KE  E ++    +   L+ ++D  + ++     A +E+  RL+ +L  L
Sbjct:   24 CELVQNMIDLSISNLEGLRTKCAA-SNDLTQKEIRTLESKLVKYFSRQLSCKKKVALQERNAELDGFPQLRHWFRIVDVRKEVLEEISPDQLSLEDLLEMTDEQVCETVEKYGANQEECARLNASLSCL 151          
BLAST of EMLSAG00000012450 vs. SwissProt
Match: gi|56748938|sp|Q61097.1|KSR1_MOUSE (RecName: Full=Kinase suppressor of Ras 1; Short=mKSR1; AltName: Full=Protein Hb)

HSP 1 Score: 64.3142 bits (155), Expect = 3.926e-10
Identity = 81/292 (27.74%), Postives = 123/292 (42.12%), Query Frame = 0
Query:   22 CGELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGR-QWSAVEGIPC--LSDL--YPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSDLSILDSKALKEDQRRLSKALHNLLKFREAF------INKGGVYQGDLYWDS-----------WEVVPSVHTEEEHSSSSSSSIPSVLPKGDSAASSLSS--TSGSIPPPSPGPLTLSPPVIGWDRKPTPPTTPPWSTSSLLCGTAYNKMNNAASSTTKQFPSVSSSSSENHSLVKSQSHESELASRIDIV 289
            CG+LQ +ID++   L  LR  CS +S++LT++EIRTLE KL++   + Q S +   P    ++L  YP    WL +  +  E  + + Q  T       L  L  +D    KE  RR   +     + ++A          GG ++ D  W S            +++ S+      +    S   S LP  DS    LS   +   IP  + G LT  P  +      TPPTTP     + L           +    +  PS         +L +S+SHES+L +RID V
Sbjct:   39 CGQLQKLIDISIGSLRGLRTKCS-VSNDLTQQEIRTLEAKLVKYICKQQQSKLSVTPSDRTAELNSYPRFSDWLYIFNVRPEVVQEIPQELT-------LDALLEMDEAKAKEMLRRWGASTEECSRLQQALTCLRKVTGLGGEHKMDSGWSSTDARDSSLGPPMDMLSSLGRAGASTQGPRSISVSALPASDSPVPGLSEGLSDSCIPLHTSGRLT--PRAL--HSFITPPTTPQLRRHAKL--KPPRTPPPPSRKVFQLLPSFP-------TLTRSKSHESQLGNRIDDV 309          
BLAST of EMLSAG00000012450 vs. Select Arthropod Genomes
Match: EFX69435.1 (hypothetical protein DAPPUDRAFT_329047 [Daphnia pulex])

HSP 1 Score: 116.701 bits (291), Expect = 6.618e-28
Identity = 95/291 (32.65%), Postives = 145/291 (49.83%), Query Frame = 0
Query:   24 ELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSA-----VEGIPCLSDLYPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSD---LSILDSKALKEDQ-RRLSKALHNLLKFREAFIN-----KGGVYQGD--LYWDSWEVVPSV----HTEEEHSSS---SSSSIPSVLPKGDSAASSLSSTSGSIPPPSPGPLTLSPPVIGWDRKPTPPTTPPWSTSSLLCGTAYNKMNNAASSTTKQFPSVSSSSSENHSLVKSQSHESELASRIDIVDL 291
            ++  MID++++HLE LR  CS  S+EL ++EIRT+EGKL++LF +Q  A     +EG+P      P+  QWL+VVG+S+   E +  +F +  +L  LSD     I +  + KED+ RRL +AL ++ ++ E  ++       G    D  LYWDSW+    +     +  +H+ S   +SS I S++   ++     S      PP +P  L         DR   P T PP   + ++ GTA              FP           L KS SHES+LA+RID  D+
Sbjct:   24 DINAMIDIHAKHLEGLRTQCST-SAELIQQEIRTIEGKLVKLFSKQLVAKAKIPIEGLPYEVKNIPSIKQWLQVVGISQPSVETLCAKFQSLESLQELSDHEIKRIFNECSAKEDEYRRLIRALQSVKRYTEVLVHNEKEGNSGRTTPDLALYWDSWDNATKISMPMSSNIQHNDSVIQNSSPIQSIITAHETIPQMTSENRS--PPSTPSLLKGR-----GDRMKFPATPPPRKKNQVIGGTA---------PLLTDFP-----------LTKSTSHESQLANRIDGNDI 286          
BLAST of EMLSAG00000012450 vs. Select Arthropod Genomes
Match: gb|KFM62098.1| (Kinase suppressor of Ras 2, partial [Stegodyphus mimosarum])

HSP 1 Score: 107.071 bits (266), Expect = 1.325e-24
Identity = 64/156 (41.03%), Postives = 91/156 (58.33%), Query Frame = 0
Query:   22 CGELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSAVEGIPCLSDL-----YPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSDLSILD----SKALKEDQRRLSKALHNLLKFREAFINKGGVYQG---DLYWDSWE 165
            C   Q MID+N+EHL+ LR  C A S+ELT+ EIRTLE KLI+LF RQ  A    P  + L     YP   +WL+VVGL ++  E ++ + +T   L+ L +  + +    S+A  E++RRL  AL NL  + E  I +G +      DL+WDSW+
Sbjct:   17 CNTAQAMIDINAEHLDGLRTQC-ATSAELTQHEIRTLESKLIKLFSRQLVAKLKCPESATLPELVQYPRLQKWLQVVGLCQKSMENISTKISTMELLLKLPEQEVKNVMHISEAKDEEKRRLLIALRNLKAYTERQI-RGEITTAADLDLHWDSWD 170          
BLAST of EMLSAG00000012450 vs. Select Arthropod Genomes
Match: EEB14308.1 (predicted protein [Pediculus humanus corporis])

HSP 1 Score: 100.908 bits (250), Expect = 1.508e-22
Identity = 60/153 (39.22%), Postives = 91/153 (59.48%), Query Frame = 0
Query:   25 LQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWS-----AVEGIPCLSDLYPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSD----LSILDSKALKEDQRRLSKALHNLLKFREAFINKGGVYQGD---LYWDSWE 165
            LQ MID++++ LE LR  C A S+ELT++EIRTLEGKLI+LF RQ       + + +P      P   QWL+VVGLS++  + +  + ++  AL   S+      +++  A +E+ RRL +ALHNL K+ E  +      + +   LYWDSW+
Sbjct:   17 LQSMIDISADRLEGLRTQC-ATSAELTQQEIRTLEGKLIKLFSRQLVNKAKLSEDSLPTEMKNVPRIRQWLQVVGLSEDAVKGIMLKVSSLEALQEKSEHELRTILIERNAREEEVRRLIRALHNLRKYIEILLKGDANNESNDLKLYWDSWD 168          
BLAST of EMLSAG00000012450 vs. Select Arthropod Genomes
Match: XP_006559789.1 (PREDICTED: kinase suppressor of Ras 2 [Apis mellifera])

HSP 1 Score: 100.908 bits (250), Expect = 1.528e-22
Identity = 63/154 (40.91%), Postives = 93/154 (60.39%), Query Frame = 0
Query:   25 LQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQ------WSAVEGIPCLSDLYPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSDL---SILDSKALK--EDQRRLSKALHNLLKFREAFINKGGVYQGD--LYWDSWE 165
            +Q MID+++E LE LR  CS  S+ELT++EIRTLEGKLI+L+ +Q       +  E +P     YP+  QWLRVVGL++E  + +  +  +  AL   S+    S+L    +K  E+ RRL +AL NL ++ +  + KG +   D  LYWDSW+
Sbjct:   18 VQSMIDISAERLEGLRTQCST-SAELTQQEIRTLEGKLIKLYSKQLVTKAKLALEESLPPEMKQYPSLQQWLRVVGLTQESIQMICSKANSLEALKEKSEHELGSMLGENNIKHEEELRRLCRALRNLRRYMDVLL-KGDMDNSDMNLYWDSWD 169          
BLAST of EMLSAG00000012450 vs. Select Arthropod Genomes
Match: gb|KYB26173.1| (Kinase suppressor of Ras 2-like Protein [Tribolium castaneum])

HSP 1 Score: 93.5893 bits (231), Expect = 4.307e-20
Identity = 61/150 (40.67%), Postives = 92/150 (61.33%), Query Frame = 0
Query:   25 LQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSAVEGIPCLS---DLYPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSD---LSILDSKALK-EDQRRLSKALHNLLKFREAFINKGGVYQGD--LYWDSWE 165
            +Q MIDV+++ LE LR  C A ++ELT++EIRTLEGKLI+LF  Q   ++ +   S   D  P+  QWL+VVGLS    + + Q+ +T   L   S+    +IL+ +  + E+  RL +ALHNL ++ +A + +G     D  LYWDSW+
Sbjct:   18 IQSMIDVSAQRLEGLRTQC-ATTAELTQQEIRTLEGKLIKLFSDQL--IKKLALRSGGADQIPSLIQWLQVVGLSGNSIQGLCQKISTVEELQEKSEHELRTILNDRGARPEELSRLCRALHNLKRYTDA-LKRGAKDNSDMHLYWDSWD 163          
BLAST of EMLSAG00000012450 vs. Select Arthropod Genomes
Match: gb|EFA08276.1| (Kinase suppressor of Ras 2-like Protein [Tribolium castaneum])

HSP 1 Score: 93.5893 bits (231), Expect = 4.349e-20
Identity = 61/150 (40.67%), Postives = 92/150 (61.33%), Query Frame = 0
Query:   25 LQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSAVEGIPCLS---DLYPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSD---LSILDSKALK-EDQRRLSKALHNLLKFREAFINKGGVYQGD--LYWDSWE 165
            +Q MIDV+++ LE LR  C A ++ELT++EIRTLEGKLI+LF  Q   ++ +   S   D  P+  QWL+VVGLS    + + Q+ +T   L   S+    +IL+ +  + E+  RL +ALHNL ++ +A + +G     D  LYWDSW+
Sbjct:   18 IQSMIDVSAQRLEGLRTQC-ATTAELTQQEIRTLEGKLIKLFSDQL--IKKLALRSGGADQIPSLIQWLQVVGLSGNSIQGLCQKISTVEELQEKSEHELRTILNDRGARPEELSRLCRALHNLKRYTDA-LKRGAKDNSDMHLYWDSWD 163          
BLAST of EMLSAG00000012450 vs. Select Arthropod Genomes
Match: EAA01809.5 (AGAP001482-PA [Anopheles gambiae str. PEST])

HSP 1 Score: 88.1965 bits (217), Expect = 3.384e-18
Identity = 58/169 (34.32%), Postives = 91/169 (53.85%), Query Frame = 0
Query:   25 LQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGR---------QWSAVEGIPCLSDLYPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSD---LSILDSKAL--KEDQRRLSKALHNLLKFREAF--------INKGGVYQGDLYWDSWEVVPSVH 171
            +Q MID++++ LE LR  C A S+ELT++EIRTLE KL++LF           +    +G+P   +      QWLRVVGLS     AV Q+ +T   L+   +    +I+ +     +E+ +RL++A  NL + RE          +++ G    DL+WDSW+  P+ H
Sbjct:   60 IQSMIDISADRLEGLRTQC-ATSAELTQQEIRTLETKLVKLFSDLLITKSKLPERLPAQGLPATGN---ELKQWLRVVGLSCASLNAVIQQVSTLEGLLEKDEKELRTIMGNNVYVREEEMKRLTRACGNLRRCREHLELPATDGSVSRKGTEPHDLFWDSWDRQPACH 224          
BLAST of EMLSAG00000012450 vs. Select Arthropod Genomes
Match: gb|EEC03294.1| (kinase suppressor of Ras (KSR), putative, partial [Ixodes scapularis])

HSP 1 Score: 86.2705 bits (212), Expect = 1.380e-17
Identity = 61/164 (37.20%), Postives = 90/164 (54.88%), Query Frame = 0
Query:   22 CGELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSAVE---GIPCLSDL--YPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSD------LSILDSKALKEDQRRLSKALHNLLKFREAFIN--------KGGV-YQGDLYWDSWE 165
            C   Q MID+NSEHL+ LR  C A S ELT+ EIR LE KLI+LF RQ  A +   G    ++L  YP    WL+VVGLS +  E ++ + TT+  ++   +      LS ++++  +E++RR   A+ NL  +              +G V  + DL+WDSW+
Sbjct:   21 CVTAQAMIDINSEHLDGLRTQC-ATSVELTQNEIRALETKLIKLFSRQVVAKKKYAGTENANELQHYPKLVLWLKVVGLSAKSIEGLSNKLTTFDDMLEKPEQEVKGFLSAVNAR--EEEKRRFLIAMRNLKAYTGLLTAVSAADRQLRGDVGTEVDLHWDSWD 181          
BLAST of EMLSAG00000012450 vs. Select Arthropod Genomes
Match: AHN57178.1 (kinase suppressor of ras, isoform D [Drosophila melanogaster])

HSP 1 Score: 82.8037 bits (203), Expect = 1.690e-16
Identity = 63/165 (38.18%), Postives = 88/165 (53.33%), Query Frame = 0
Query:   25 LQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSAV----EGIPCLSDLYPNA-----HQWLRVVGLSKEGREAVAQRFTTWAALVSLSDLSI----LDSKALKEDQ--RRLSKALHNLLKFREAFINKGGVYQGD---LYWDSWEVVPSVH 171
            +Q MID+++ HLE LR  C A+SS LT++EIR LE KL++ F     A     E IP  + L P+       QWLRVVGLS+    A   R TT    + LSD  I     DS + +E++  RRL++A+ NL K  E+  +       D    +WDSW+    +H
Sbjct:   36 IQDMIDLSANHLEGLRTQC-AISSTLTQQEIRCLESKLVRYFSELLLAKMRLNERIPA-NGLVPHTTGNELRQWLRVVGLSQGTLTACLARLTTLEQSLRLSDEEIRQLLADSPSQREEEELRRLTRAMQNLRKCMESLESGTAASNNDPEQWHWDSWDRPTHIH 198          
BLAST of EMLSAG00000012450 vs. Select Arthropod Genomes
Match: AHN57177.1 (kinase suppressor of ras, isoform C [Drosophila melanogaster])

HSP 1 Score: 82.8037 bits (203), Expect = 1.690e-16
Identity = 63/165 (38.18%), Postives = 88/165 (53.33%), Query Frame = 0
Query:   25 LQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSAV----EGIPCLSDLYPNA-----HQWLRVVGLSKEGREAVAQRFTTWAALVSLSDLSI----LDSKALKEDQ--RRLSKALHNLLKFREAFINKGGVYQGD---LYWDSWEVVPSVH 171
            +Q MID+++ HLE LR  C A+SS LT++EIR LE KL++ F     A     E IP  + L P+       QWLRVVGLS+    A   R TT    + LSD  I     DS + +E++  RRL++A+ NL K  E+  +       D    +WDSW+    +H
Sbjct:   36 IQDMIDLSANHLEGLRTQC-AISSTLTQQEIRCLESKLVRYFSELLLAKMRLNERIPA-NGLVPHTTGNELRQWLRVVGLSQGTLTACLARLTTLEQSLRLSDEEIRQLLADSPSQREEEELRRLTRAMQNLRKCMESLESGTAASNNDPEQWHWDSWDRPTHIH 198          
BLAST of EMLSAG00000012450 vs. nr
Match: gi|321458366|gb|EFX69435.1| (hypothetical protein DAPPUDRAFT_329047 [Daphnia pulex])

HSP 1 Score: 116.701 bits (291), Expect = 3.238e-25
Identity = 95/291 (32.65%), Postives = 145/291 (49.83%), Query Frame = 0
Query:   24 ELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSA-----VEGIPCLSDLYPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSD---LSILDSKALKEDQ-RRLSKALHNLLKFREAFIN-----KGGVYQGD--LYWDSWEVVPSV----HTEEEHSSS---SSSSIPSVLPKGDSAASSLSSTSGSIPPPSPGPLTLSPPVIGWDRKPTPPTTPPWSTSSLLCGTAYNKMNNAASSTTKQFPSVSSSSSENHSLVKSQSHESELASRIDIVDL 291
            ++  MID++++HLE LR  CS  S+EL ++EIRT+EGKL++LF +Q  A     +EG+P      P+  QWL+VVG+S+   E +  +F +  +L  LSD     I +  + KED+ RRL +AL ++ ++ E  ++       G    D  LYWDSW+    +     +  +H+ S   +SS I S++   ++     S      PP +P  L         DR   P T PP   + ++ GTA              FP           L KS SHES+LA+RID  D+
Sbjct:   24 DINAMIDIHAKHLEGLRTQCST-SAELIQQEIRTIEGKLVKLFSKQLVAKAKIPIEGLPYEVKNIPSIKQWLQVVGISQPSVETLCAKFQSLESLQELSDHEIKRIFNECSAKEDEYRRLIRALQSVKRYTEVLVHNEKEGNSGRTTPDLALYWDSWDNATKISMPMSSNIQHNDSVIQNSSPIQSIITAHETIPQMTSENRS--PPSTPSLLKGR-----GDRMKFPATPPPRKKNQVIGGTA---------PLLTDFP-----------LTKSTSHESQLANRIDGNDI 286          
BLAST of EMLSAG00000012450 vs. nr
Match: gi|970892174|ref|XP_015111419.1| (PREDICTED: kinase suppressor of Ras 2 [Diachasma alloeum])

HSP 1 Score: 116.701 bits (291), Expect = 3.401e-25
Identity = 109/315 (34.60%), Postives = 149/315 (47.30%), Query Frame = 0
Query:    5 ECEEDEEGSLLRHRRCTCGELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSA-----VEGIPCLSDLYPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSDLSI-----LDSKALKEDQRRLSKALHNLLKFREAFINKGGVYQG---DLYWDSWEV---------VPSVHTEEEHSSSSSSSIP----------SVLPKGDSAASSLSSTSGSIPPPSPGPLTLSPPVIGWDRKPTPPTTPPWSTSSLLCGTAYNKMNNAASSTTKQFPSVSSSSSENHSLVKSQSHESELASRID 287
            E EE E+ S     R     +Q MID++++ LE LR  CS  S+ELT++EIRTLEGKLI+L+  Q        V+ +P     YP+ HQWLRVVGL+ E    V  +  T  AL   S+  +      ++   +E+ RRL +ALHNL ++ +  + +GG   G   +LYWDSW+           P        S  S  SIP          +  P+  + ASS+ S + S  PPS  P+ L   V         PTTPP S           + N   S     FP           L KS+SHES+LASRI+
Sbjct:    3 ETEEPEQDS-----RRALYVVQSMIDISADRLEGLRTKCST-SAELTQQEIRTLEGKLIKLYSEQLVEKSKLPVDSLPPEMRQYPSLHQWLRVVGLTPESIRNVCTKAQTLEALKEKSEHELGTMLGENTTRHEEELRRLCRALHNLRRYIDVLLQRGGDESGEMLNLYWDSWDRHHLRGGTSPRPVRSRATRRSIPSDDSIPYNNNNNNNDNNNFPETLAQASSIISLTTS--PPS-TPVLLRQAV-------KFPTTPPPS----------KRHNAVLSPLPDVFP-----------LTKSKSHESQLASRIE 280          
BLAST of EMLSAG00000012450 vs. nr
Match: gi|1022777170|gb|KZS20755.1| (Kinase suppressor of Ras 1 [Daphnia magna])

HSP 1 Score: 116.701 bits (291), Expect = 3.559e-25
Identity = 96/297 (32.32%), Postives = 146/297 (49.16%), Query Frame = 0
Query:   24 ELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSA-----VEGIPCLSDLYPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSD---LSILDSKALKEDQ-RRLSKALHNLLKFREAFINK-----GGVYQGD--LYWDSWEVVPSVHTEEEHSSSSSSSI---PSVLPKGDSAASSLSSTS--GSIPPPSPGPLTLSPPVIGWDRKPTPPTTPPWSTSSLLCGTAYNKMNNAASSTTKQFPSVSSSSSENHSLVKSQSHESELASRIDIVDLGXGHSTVI 299
            ++  MID++++HLE LR  CS  S+EL ++EIRT+EGKL++LF +Q  A     +EGIP      P+  QWL+VVG+S+   EA+  +F +  +L  L D     I +    KED+ RRL +AL ++ ++ E  ++       G    D  LYWDSW+ V         S+  + +I   P  +    +   ++  T+     PP +P  L         DR   P T PP   + ++ G         A+     FP           L KS SHES+LA+RID  D+  G ST++
Sbjct:   23 DISAMIDIHAKHLEGLRTQCST-SAELIQQEIRTIEGKLVKLFSKQLVAKAKIPIEGIPYEVRNIPSIKQWLQVVGISQPSVEALCAKFQSLESLQELCDHEIKRIFNECYAKEDEYRRLIRALQSVKRYTEVLVHNEKEGSSGRTTPDLALYWDSWDNVTQALLPITTSAQQNENIMHNPLNIQNIHTVHETIPQTAPENRSPPSTPSVLKGR-----GDRMKFPATPPPRKKNQVIGG---------AAPLLTDFP-----------LTKSTSHESQLANRIDGNDVVSGASTML 293          
BLAST of EMLSAG00000012450 vs. nr
Match: gi|752894960|ref|XP_011265680.1| (PREDICTED: kinase suppressor of Ras 2 [Camponotus floridanus] >gi|307169064|gb|EFN61908.1| Kinase suppressor of Ras 2 [Camponotus floridanus])

HSP 1 Score: 114.39 bits (285), Expect = 2.048e-24
Identity = 101/291 (34.71%), Postives = 149/291 (51.20%), Query Frame = 0
Query:   24 ELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSAVEGIPCLSDL--YPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSDL---SILDSKALK--EDQRRLSKALHNLLKFREAFINKGGVYQGD--LYWDSWE---VVPSVHTEEEHSSSSSSSIPS--VLPKGD---------SAASSLSSTSGSIPPPSPGPLTLSPPVIGWDRKPTPPTTPPWSTSSLLCGTAYNKMNNAASSTTKQFPSVSSSSSENHSLVKSQSHESELASRIDIVDL 291
            ++Q MIDV +E LE LR  CS  S+ELT++EIRTLEGKLI+L+ +Q      +  L+++  YP+  QWLRVVGL++E  + V  + ++  AL   S+    S+L    ++  E+ RRL +ALHNL ++ +  I KG +   D  LYWDSW+   +          S ++ SS+PS   +P  +         + ASS+ S   + PP +  PL       G       PTTPP             K      S+T Q         E   L KS+SHES+LA+R++ + L
Sbjct:   14 DVQSMIDVCAERLEGLRTQCST-SAELTQQEIRTLEGKLIKLYSKQLVTKAKLTDLAEMRQYPSLQQWLRVVGLTQESIQMVCNKASSLEALKEKSEHELSSMLGENNVRREEEHRRLCRALHNLRRYTDVLI-KGDMENSDMNLYWDSWDRHHLRTGASPRPIRSRTTRSSVPSEDSIPYHNNNNLNSDILAQASSVISLMSTSPPCT--PLLQQRQKYGTKF----PTTPP----------PCKKHQIGVQSSTSQ--------PEVFPLTKSKSHESQLANRLENIQL 278          
BLAST of EMLSAG00000012450 vs. nr
Match: gi|861640898|gb|KMQ93355.1| (kinase suppressor of ras 2-like protein [Lasius niger])

HSP 1 Score: 114.005 bits (284), Expect = 2.065e-24
Identity = 98/292 (33.56%), Postives = 150/292 (51.37%), Query Frame = 0
Query:   24 ELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSAVEGIPCLSDL--YPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSDL---SILDSKALK--EDQRRLSKALHNLLKFREAFINKGGVYQGD--LYWDSWE---VVPSVHTEEEHSSSSSSSIPS--VLPKGD---------SAASSLSSTSGSIPPPSPGPLTLSPPVIGWDRKPTP-PTTPPWSTSSLLCGTAYNKMNNAASSTTKQFPSVSSSSSENHSLVKSQSHESELASRIDIVDL 291
            ++Q MIDV +E LE LR  CS  S+ELT++EIRTLEGKLI+L+ +Q      +   +++  YP+  QWLRVVGL++E  + V  + ++  AL   S+    S+L    ++  E+ RRL +ALHNL ++ +  I +G +   D  LYWDSW+   +          S ++ SS+PS   +P  +         + ASS+ S   + PP +        P++   +  T  PTTPP             K      S+T Q         E   L KS+SHES+LA+R++ + L
Sbjct:   14 DVQSMIDVCAERLEGLRTQCST-SAELTQQEIRTLEGKLIKLYSKQLVTKAKLADFAEMRQYPSLQQWLRVVGLTQESIQTVCNKASSLEALKEKSEHELSSMLSENNVRREEEHRRLCRALHNLRRYTDVLI-RGDMENSDMNLYWDSWDRHHLRTGASPRPIRSRTTRSSVPSEDSIPYHNNNNLNSDILAQASSVISLMSTSPPCT--------PLLHRQKYGTKFPTTPP----------PCKKHQIGVQSSTSQ--------PEVFPLTKSKSHESQLANRLENIQL 277          
BLAST of EMLSAG00000012450 vs. nr
Match: gi|817195177|ref|XP_012273123.1| (PREDICTED: kinase suppressor of Ras 2 isoform X3 [Orussus abietinus])

HSP 1 Score: 113.235 bits (282), Expect = 5.826e-24
Identity = 99/293 (33.79%), Postives = 151/293 (51.54%), Query Frame = 0
Query:   25 LQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWS-----AVEGIPCLSDLYPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSDL---SILDSKALK--EDQRRLSKALHNLLKFREAFINKGGV--YQGDLYWDSWE---VVPSVHTEEEHSSSSSSSIPS--VLPKGDS----------AASSLSSTSGSIPPPSPGPLTLSPPVIGWDRKPTPPTTPPWSTSSLLCGTAYNKMNNAASSTTKQFPSVSSSSSENHSLVKSQSHESELASRIDIVD 290
            +Q MID++++ LE LR  CS  S+ELT++EIRTLEGKLI+L+ +Q       AVE +P     YP+  QWLRVVGL+++  + V  +  +  AL   S+    S+L    ++  E+ RRLS+ALHNL ++ +  + +G +   + +LYWDSW+   V          S ++ SS+PS   +P  ++           A+S+ S S + PP        +P +    R    PTTPP            NK +     +T   P V         L KS+SHES+LA+R++  D
Sbjct:   18 VQSMIDISADRLEGLRTQCST-SAELTQQEIRTLEGKLIKLYSKQLVTKAKLAVESLPAEMRQYPSLQQWLRVVGLTQKSIQMVCSKANSLEALKEKSEHELGSMLGENNVRHEEELRRLSRALHNLRRYMDVLL-RGDMDNSEMNLYWDSWDRHHVRSGPSPRPIRSRTTRSSVPSEDSIPYHNNNFSVNSNTMMQAASVISLSSTSPP-------TTPLLSRHGRGVKFPTTPP-----------PNKRHQTGLQSTVSQPEV-------FPLTKSKSHESQLANRLENGD 283          
BLAST of EMLSAG00000012450 vs. nr
Match: gi|817195181|ref|XP_012273126.1| (PREDICTED: kinase suppressor of Ras 2 isoform X5 [Orussus abietinus])

HSP 1 Score: 112.849 bits (281), Expect = 7.144e-24
Identity = 99/293 (33.79%), Postives = 151/293 (51.54%), Query Frame = 0
Query:   25 LQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWS-----AVEGIPCLSDLYPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSDL---SILDSKALK--EDQRRLSKALHNLLKFREAFINKGGV--YQGDLYWDSWE---VVPSVHTEEEHSSSSSSSIPS--VLPKGDS----------AASSLSSTSGSIPPPSPGPLTLSPPVIGWDRKPTPPTTPPWSTSSLLCGTAYNKMNNAASSTTKQFPSVSSSSSENHSLVKSQSHESELASRIDIVD 290
            +Q MID++++ LE LR  CS  S+ELT++EIRTLEGKLI+L+ +Q       AVE +P     YP+  QWLRVVGL+++  + V  +  +  AL   S+    S+L    ++  E+ RRLS+ALHNL ++ +  + +G +   + +LYWDSW+   V          S ++ SS+PS   +P  ++           A+S+ S S + PP        +P +    R    PTTPP            NK +     +T   P V         L KS+SHES+LA+R++  D
Sbjct:   18 VQSMIDISADRLEGLRTQCST-SAELTQQEIRTLEGKLIKLYSKQLVTKAKLAVESLPAEMRQYPSLQQWLRVVGLTQKSIQMVCSKANSLEALKEKSEHELGSMLGENNVRHEEELRRLSRALHNLRRYMDVLL-RGDMDNSEMNLYWDSWDRHHVRSGPSPRPIRSRTTRSSVPSEDSIPYHNNNFSVNSNTMMQAASVISLSSTSPP-------TTPLLSRHGRGVKFPTTPP-----------PNKRHQTGLQSTVSQPEV-------FPLTKSKSHESQLANRLENGD 283          
BLAST of EMLSAG00000012450 vs. nr
Match: gi|939253548|ref|XP_014246449.1| (PREDICTED: kinase suppressor of Ras 2 isoform X1 [Cimex lectularius])

HSP 1 Score: 112.464 bits (280), Expect = 9.192e-24
Identity = 105/290 (36.21%), Postives = 151/290 (52.07%), Query Frame = 0
Query:   17 HRRCTCGELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQW---SAVEGIPCLSDLYPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLS--DLSIL----DSKALKEDQRRLSKALHNLLKFREAFINKGGVYQGD--LYWDSWEVVPSVHTEEEHSSSSSSSIPSVLPKGDSAASSLSSTSGSIPPP----SPGPLTLSPPVIGWDRKPTPPTTPPWSTSSLLCGTAYNKMNNAASSTTKQFPSVSSSS----SENHSLVKSQSHESELASRID 287
            HRR T   LQ MID +++ LE LR  C A S+ELT+ EIRTLEGKLI+LF  Q    S ++     +   P+  QWL+VVGLS E  EA+  R  +   L   S  +L +L     S   +E+ RRL++ALHNL K+ E  + KG     +  LYWDSW+             S++S++ S  P+  S   S++  +GS  P     +PG L+    VIG     +PP+TPP + S    G+   +    ++   K        S     + H L KS+SHES+LA+++D
Sbjct:    8 HRR-TLDVLQSMIDTSADRLEGLRTKC-ATSAELTQHEIRTLEGKLIKLFSSQLTIKSKLKDTNADTRQLPSVQQWLQVVGLSHESIEAICVRVRSIDVLQEKSEHELKMLLNSDHSSFRQEELRRLNRALHNLKKYTEILV-KGECEACELPLYWDSWD------------RSAASNVLS--PR--SQLRSVNRIAGSRLPADLDETPGILS---GVIGGQM--SPPSTPPVNKSKESTGSVGERGKFPSTPPPKMKHQTGLHSVVLLPDTHPLTKSKSHESQLANKVD 273          
BLAST of EMLSAG00000012450 vs. nr
Match: gi|942410563|gb|JAN87211.1| (Kinase suppressor of Ras [Daphnia magna])

HSP 1 Score: 112.079 bits (279), Expect = 1.171e-23
Identity = 93/289 (32.18%), Postives = 141/289 (48.79%), Query Frame = 0
Query:   24 ELQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWSA-----VEGIPCLSDLYPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSD---LSILDSKALKEDQ-RRLSKALHNLLKFREAFINK-----GGVYQGD--LYWDSWEVVPSVHTEEEHSSSSSSSI---PSVLPKGDSAASSLSSTS--GSIPPPSPGPLTLSPPVIGWDRKPTPPTTPPWSTSSLLCGTAYNKMNNAASSTTKQFPSVSSSSSENHSLVKSQSHESELASRIDIVDL 291
            ++  MID++++HLE LR  CS  S+EL ++EIRT+EGKL++LF +Q  A     +EGIP      P+  QWL+VVG+S+   EA+  +F +  +L  L D     I +    KED+ RRL +AL ++ ++ E  ++       G    D  LYWDSW+ V         S+  + +I   P  +    +   ++  T+     PP +P  L         DR   P T PP   + ++ G         A+     FP           L KS SHES+LA+RID  D+
Sbjct:   23 DISAMIDIHAKHLEGLRTQCST-SAELIQQEIRTIEGKLVKLFSKQLVAKAKIPIEGIPYEVRNIPSIKQWLQVVGISQPSVEALCAKFQSLESLQELCDHEIKRIFNECYAKEDEYRRLIRALQSVKRYTEVLVHNEKEGSSGRTTPDLALYWDSWDNVTQALLPITTSAQQNENIMHNPLNIQNIHTVHETIPQTAPENRSPPSTPSVLKGR-----GDRMKFPATPPPRKKNQVIGG---------AAPLLTDFP-----------LTKSTSHESQLANRIDGNDV 285          
BLAST of EMLSAG00000012450 vs. nr
Match: gi|817195175|ref|XP_012273122.1| (PREDICTED: kinase suppressor of Ras 2 isoform X2 [Orussus abietinus])

HSP 1 Score: 112.079 bits (279), Expect = 1.479e-23
Identity = 98/293 (33.45%), Postives = 151/293 (51.54%), Query Frame = 0
Query:   25 LQIMIDVNSEHLETLRNTCSALSSELTKREIRTLEGKLIQLFGRQWS-----AVEGIPCLSDLYPNAHQWLRVVGLSKEGREAVAQRFTTWAALVSLSDL---SILDSKALK--EDQRRLSKALHNLLKFREAFINKGGV--YQGDLYWDSWE---VVPSVHTEEEHSSSSSSSIPS--VLPKGDS----------AASSLSSTSGSIPPPSPGPLTLSPPVIGWDRKPTPPTTPPWSTSSLLCGTAYNKMNNAASSTTKQFPSVSSSSSENHSLVKSQSHESELASRIDIVD 290
            +Q MID++++ LE LR  CS  S+ELT++EIRTLEGKLI+L+ +Q       AVE +P     YP+  QWLRVVGL+++  + V  +  +  AL   S+    S+L    ++  E+ RRLS+ALHNL ++ +  + +G +   + +LYWDSW+   V          S ++ SS+PS   +P  ++           A+S+ S S + PP +P         + +      PTTPP            NK +     +T   P V         L KS+SHES+LA+R++  D
Sbjct:   18 VQSMIDISADRLEGLRTQCST-SAELTQQEIRTLEGKLIKLYSKQLVTKAKLAVESLPAEMRQYPSLQQWLRVVGLTQKSIQMVCSKANSLEALKEKSEHELGSMLGENNVRHEEELRRLSRALHNLRRYMDVLL-RGDMDNSEMNLYWDSWDRHHVRSGPSPRPIRSRTTRSSVPSEDSIPYHNNNFSVNSNTMMQAASVISLSSTSPPTTPLLSRHGRAGVKF------PTTPP-----------PNKRHQTGLQSTVSQPEV-------FPLTKSKSHESQLANRLENGD 284          
BLAST of EMLSAG00000012450 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold1671_size31647-snap-gene-0.10 (protein:Tk04556 transcript:maker-scaffold1671_size31647-snap-gene-0.10-mRNA-1 annotation:"kinase suppressor of ras 1")

HSP 1 Score: 135.576 bits (340), Expect = 2.044e-35
Identity = 118/375 (31.47%), Postives = 169/375 (45.07%), Query Frame = 0
Query:   22 CGELQIMIDVNSEHLETLRN-------TCSALSSELTKREIRTLEGKLIQLFGRQWSA--------VEGIPCLSDLYPNAHQWLRVVGLSKEGREAVAQRFTTWAAL----------VSLSDLSILDSKALKEDQRRLSKALHNLLKFREAFINKG---------GVYQG---DLYWDSWEVVPSVHTEEEHSSSSSSSIPSVLPKGDSAASSLSSTSGSIP-------PPSPGP----------------------LTLSPPVIGW-DRKPTPPTTPPWSTSSLLCGTAYNKMNNAASSTTKQFPSVSSSSSENHSLVKSQSHESELASRID----IVDLGXGHSTVIHYQHHSYSSNTHFKQQQRLGRPRLAT 325
            C   Q MID+N+EHL++LR+       TCSA  SE+TK+EIRTLEGKL++LF +Q +          E  P L D YP+  QWL VVG++ E + A+  R++T   L          + L+  S L      ED RRL +AL NL K+ ++ +  G         G  +    DLYWDSW           HS ++S      +P     +  L +  GS+P        P  G                       LTLSPPV+ W +R+ TPPTTPPWS +++    + ++         K+  +V+++    + L KS+S E E   RI+        G G   ++   H S  S  H         PR AT
Sbjct:   26 CENFQHMIDINAEHLDSLRSSQSATGPTCSA-GSEITKQEIRTLEGKLVKLFSQQLALRASLSHQDCELYPWLKD-YPSLAQWLMVVGITAESQMAILSRWSTLEQLKEKTEPELNRLLLASASKLSKTHRNEDLRRLVRALQNLRKYTDSLMLHGTHQPPPHAQGALEASHVDLYWDSW-----------HSGTTSRVSADRIP---GKSGDLGAGHGSVPLSVAHTSYPFRGDSASSSVSSSSSAASSLPPPSPGLTLSPPVMPWPERRATPPTTPPWSAAAIFGNKSQSQKFPTTPPPNKKHSTVATAGKNEYPLTKSKSQEGEATHRINGPGANCGSGVGGGAILMPHHESLMSLPHKSSSILPTTPRPAT 384          
The following BLAST results are available for this feature:
BLAST of EMLSAG00000012450 vs. GO
Analysis Date: 2014-04-02 (Blast vs. GO)
Total hits: 13
Match NameE-valueIdentityDescription
-4.453e-1638.18symbol:ksr "kinase suppressor of ras" species:7227... [more]
-8.132e-1328.98symbol:KSR1 "Uncharacterized protein" species:9031... [more]
-2.964e-1030.32symbol:KSR2 "Kinase suppressor of Ras 2" species:9... [more]
-3.137e-1032.56symbol:Ksr2 "kinase suppressor of ras 2" species:1... [more]
-3.614e-1030.32symbol:KSR2 "Uncharacterized protein" species:9913... [more]
-3.955e-1030.32symbol:KSR2 "Uncharacterized protein" species:9615... [more]
-5.389e-1027.74symbol:Ksr1 "kinase suppressor of ras 1" species:1... [more]
-2.076e-928.05symbol:KSR1 "Kinase suppressor of Ras 1" species:9... [more]
-2.302e-928.05symbol:KSR1 "Kinase suppressor of Ras 1" species:9... [more]
-2.497e-928.05symbol:KSR1 "Kinase suppressor of Ras 1" species:9... [more]

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BLAST of EMLSAG00000012450 vs. C. finmarchicus
Analysis Date: 2014-05-09 (TblastN vs C. finmarchicus TSA)
Total hits: 2
Match NameE-valueIdentityDescription
gi|592822342|gb|GAXK01132226.1|2.552e-1937.04TSA: Calanus finmarchicus comp26594_c0_seq2 transc... [more]
gi|592822343|gb|GAXK01132225.1|2.569e-1937.04TSA: Calanus finmarchicus comp26594_c0_seq1 transc... [more]
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BLAST of EMLSAG00000012450 vs. L. salmonis peptides
Analysis Date: 2014-05-10 (Blastp vs. self)
Total hits: 1
Match NameE-valueIdentityDescription
EMLSAP000000124500.000e+0100.00pep:novel supercontig:LSalAtl2s:LSalAtl2s9156:540:... [more]
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BLAST of EMLSAG00000012450 vs. SwissProt
Analysis Date: 2017-02-10 (Blastp vs. SwissProt)
Total hits: 3
Match NameE-valueIdentityDescription
gi|148886599|sp|Q6VAB6.2|KSR2_HUMAN2.162e-1030.32RecName: Full=Kinase suppressor of Ras 2; Short=hK... [more]
gi|147647674|sp|Q3UVC0.2|KSR2_MOUSE2.288e-1032.56RecName: Full=Kinase suppressor of Ras 2[more]
gi|56748938|sp|Q61097.1|KSR1_MOUSE3.926e-1027.74RecName: Full=Kinase suppressor of Ras 1; Short=mK... [more]
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BLAST of EMLSAG00000012450 vs. Select Arthropod Genomes
Analysis Date: 2017-02-20 (Blastp vs. Selected Arthropods)
Total hits: 12
Match NameE-valueIdentityDescription
EFX69435.16.618e-2832.65hypothetical protein DAPPUDRAFT_329047 [Daphnia pu... [more]
gb|KFM62098.1|1.325e-2441.03Kinase suppressor of Ras 2, partial [Stegodyphus m... [more]
EEB14308.11.508e-2239.22predicted protein [Pediculus humanus corporis][more]
XP_006559789.11.528e-2240.91PREDICTED: kinase suppressor of Ras 2 [Apis mellif... [more]
gb|KYB26173.1|4.307e-2040.67Kinase suppressor of Ras 2-like Protein [Tribolium... [more]
gb|EFA08276.1|4.349e-2040.67Kinase suppressor of Ras 2-like Protein [Tribolium... [more]
EAA01809.53.384e-1834.32AGAP001482-PA [Anopheles gambiae str. PEST][more]
gb|EEC03294.1|1.380e-1737.20kinase suppressor of Ras (KSR), putative, partial ... [more]
AHN57178.11.690e-1638.18kinase suppressor of ras, isoform D [Drosophila me... [more]
AHN57177.11.690e-1638.18kinase suppressor of ras, isoform C [Drosophila me... [more]

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BLAST of EMLSAG00000012450 vs. nr
Analysis Date: 2017-02-20 (Blastp vs. NR (2/2017))
Total hits: 25
Match NameE-valueIdentityDescription
gi|321458366|gb|EFX69435.1|3.238e-2532.65hypothetical protein DAPPUDRAFT_329047 [Daphnia pu... [more]
gi|970892174|ref|XP_015111419.1|3.401e-2534.60PREDICTED: kinase suppressor of Ras 2 [Diachasma a... [more]
gi|1022777170|gb|KZS20755.1|3.559e-2532.32Kinase suppressor of Ras 1 [Daphnia magna][more]
gi|752894960|ref|XP_011265680.1|2.048e-2434.71PREDICTED: kinase suppressor of Ras 2 [Camponotus ... [more]
gi|861640898|gb|KMQ93355.1|2.065e-2433.56kinase suppressor of ras 2-like protein [Lasius ni... [more]
gi|817195177|ref|XP_012273123.1|5.826e-2433.79PREDICTED: kinase suppressor of Ras 2 isoform X3 [... [more]
gi|817195181|ref|XP_012273126.1|7.144e-2433.79PREDICTED: kinase suppressor of Ras 2 isoform X5 [... [more]
gi|939253548|ref|XP_014246449.1|9.192e-2436.21PREDICTED: kinase suppressor of Ras 2 isoform X1 [... [more]
gi|942410563|gb|JAN87211.1|1.171e-2332.18Kinase suppressor of Ras [Daphnia magna][more]
gi|817195175|ref|XP_012273122.1|1.479e-2333.45PREDICTED: kinase suppressor of Ras 2 isoform X2 [... [more]

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BLAST of EMLSAG00000012450 vs. Tigriopus kingsejongenis genes
Analysis Date: 2018-04-18 (Blastp vs. Tigriopus kingsejongensis proteins)
Total hits: 1
Match NameE-valueIdentityDescription
maker-scaffold1671_size31647-snap-gene-0.102.044e-3531.47protein:Tk04556 transcript:maker-scaffold1671_size... [more]
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Alignments
The following features are aligned
Aligned FeatureFeature TypeAlignment Location
LSalAtl2s9156supercontigLSalAtl2s9156:540..1591 -
Analyses
This gene is derived from or has results from the following analyses
Analysis NameDate Performed
ensembl2013-09-26 .965016
Blast vs. GO2014-04-02
TblastN vs C. finmarchicus TSA2014-05-09
Blastp vs. self2014-05-10
Blastp vs. SwissProt2017-02-10
Blastp vs. Selected Arthropods2017-02-20
Blastp vs. NR (2/2017)2017-02-20
Blastp vs. Tigriopus kingsejongensis proteins2018-04-18
Properties
Property NameValue
Logic nameensemblgenomes
Descriptionmaker-LSalAtl2s9156-snap-gene-0.3
Biotypeprotein_coding
EvidenceIEA
NoteKinase suppressor of Ras 2
Cross References
External references for this gene
DatabaseAccession
Ensembl Metazoa (gene)EMLSAG00000012450 (primary cross-reference)
Relationships

The following mRNA feature(s) are a part of this gene:

Feature NameUnique NameSpeciesType
EMLSAT00000012450EMLSAT00000012450-708297Lepeophtheirus salmonismRNA


Sequences
The following sequences are available for this feature:

gene from alignment at LSalAtl2s9156:540..1591-

Legend: mRNA
Hold the cursor over a type above to highlight its positions in the sequence below.
>EMLSAG00000012450-695216 ID=EMLSAG00000012450-695216|Name=EMLSAG00000012450|organism=Lepeophtheirus salmonis|type=gene|length=1052bp|location=Sequence derived from alignment at LSalAtl2s9156:540..1591- (Lepeophtheirus salmonis)
ATGAGGACAATGGAGTGTGAGGAGGATGAAGAAGGTTCCCTCCTCCGTCA CCGACGATGTACTTGTGGAGAGCTCCAGATTATGATCGACGTCAACTCTG AGCATTTGGAGACGCTCCGCAACACTTGTTCAGCTCTAAGTTCCGAGCTG ACCAAGAGAGAGATCCGGACGCTGGAAGGGAAACTCATTCAGCTGTTTGG GCGTCAGTGGTCTGCCGTGGAGGGGATTCCCTGCCTCTCGGACTTGTATC CCAATGCGCATCAATGGCTCAGAGTCGTAGGCCTTTCCAAAGAAGGGCGG GAGGCTGTGGCTCAGCGATTTACCACTTGGGCCGCACTCGTCTCCCTCTC GGACCTCTCCATTCTTGATTCCAAAGCACTCAAAGAGGATCAGAGGTAGG ATACTCAGTCTCTCCTCATCAAGCATTTCCTTTTCTCTTTTACAGGCGAC TAAGTAAAGCCCTGCACAATCTTCTCAAGTTCCGCGAAGCCTTCATTAAC AAAGGGGGCGTTTATCAAGGAGATCTCTACTGGGATTCCTGGGAAGTTGT ACCATCAGTCCACACTGAGGAAGAGCATTCCTCTTCTTCGTCCTCATCTA TTCCTTCAGTCTTACCAAAAGGGGATTCAGCAGCATCTTCCTTAAGTTCC ACTTCAGGTTCCATCCCTCCGCCCTCCCCTGGACCTCTCACTCTCAGTCC GCCGGTTATAGGATGGGATAGAAAACCAACGCCTCCTACAACCCCTCCAT GGTCCACTTCATCTCTTCTGTGTGGAACGGCTTATAATAAAATGAACAAC GCTGCGAGTAGCACCACTAAACAGTTTCCTTCTGTATCATCATCCAGCTC TGAAAATCATTCACTTGTAAAATCTCAGTCGCATGAATCAGAACTGGCTA GTCGAATTGATATTGTGGATCTAGGAGSAGGGCACTCCACGGTTATACAT TATCAACATCATTCCTATTCAAGTAATACCCACTTCAAGCAGCAACAAAG ACTTGGTCGTCCCAGACTAGCAACAGAGCCCTCTATCTTGCCAACAGATG AA
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