Query:  225 QGDCEICGHLAKMFCSCCKHVFYCTREHQKKHWKSHKEDCSALKKLPYRVERNGELGRHLVATTDIPAGTHFLNESPMVMGPRQMSKPVCLGCHKELVDLESVVKCSRCLWPLCSRKCEDSKLH-EPECRVIKYGGSKVNVESFGQVNMMYACITVLRALALQDGAQTIWKDYTKFESHLDKRMETEIYTKVNKEKVVYFIHYFLKLINKYSDLEILETCGRLDTNCFEIKQNGMNLRAMYRVACIISHDCCPNTKHTFDPDHSINLFATTNIRKGSIISATYTQSIWNTMNRRAHLYMSKCFWCQCRRCRDPTEFGTYLSANSCNACGGQVIPTQPLDNSAKW 567
            QGDC +CG LAK FCS CK+VFYC REHQK HW SH ++C+  K LPYR+ERN  LGR+LVA  DI  G+   NE P+V+GPRQ++K VCL CH EL D +    C RC WP+CSR C DS +H   EC ++ YGG KVN+++FG  NMMYACITVLRAL+L++  +  W++Y KF+SHL++RM T++Y +VNKEKVV+FIHYFLKL++K+SDLEILE CG+LDTNCFEI+Q G NLR +YR+  I+SH+C PNT+HTF+ ++ IN+++T +I+KG II ATYTQ +W T++RR HL MSKCFWC+C+RC DPTEFGTYLSA SC+ CGG+++P  PLD  + W
Sbjct:  134 QGDCIVCGELAKNFCSSCKYVFYCKREHQKSHWSSHSKECAHFKALPYRIERNPRLGRYLVAKDDISEGSLIFNEPPLVIGPRQLTKAVCLXCHNELKDKKDTYPCRRCTWPMCSRSCSDSPVHANAECSILSYGGVKVNIDAFGTANMMYACITVLRALSLKNDHK--WQEYLKFDSHLNERMPTQVYQQVNKEKVVFFIHYFLKLLSKFSDLEILEACGKLDTNCFEIRQFGKNLRGLYRIGSIMSHECTPNTRHTFEENYDINVYSTVDIKKGEIICATYTQPLWCTLSRREHLNMSKCFWCRCKRCSDPTEFGTYLSAFSCSECGGKMLPLDPLDQKSNW 475          

Query:  220 SDGKPQGDCEICGHLAKMFCSCCKHVFYCTREHQKKHWKSHKEDCSALKKLPYRVERNGELGRHLVATTDIPAGTHFLNESPMVMGPRQMSKPVCLGCHKELVDLESVVKCSRCLWPLCSRKCEDSKLHEPECRVIKYGGSKVNVE-SFGQVNMMYACITVLRALALQDGAQTIWKDYTKFESHLDKRMETEIYTKVNKEKVVYFIHYFLKL-INKYSDLEILETCGRLDTNCFEIKQNGMNLRAMYRVACIISHDCCPNTKHTFDPDHSINLFATTNIRKGSIISATYTQSIWNTMNRRAHLYMSKCFWCQCRRCRDPTEFGTYLSANSCNAC-GGQVIPTQPLDNSAKW 567
            ++ + Q  C  C   A   C+ C   FYC+REHQK HWK HK  C +     Y++  +  LGR+L AT D+  G   L E+P ++ P  ++ PVCL C+     ++    C  C WP+C+  C +S  H PECR+    GS + +  +  +   +Y  + +LR L +++ +   +K   + E H  +R++   Y++ +K  ++  I  F  +   ++ D +IL  CG L  N  E+       +A+Y+ A ++ H C  N    FD + +I +     I+KG  IS  Y+  IW T+NR+ HL  +K F C+C RC+DPTE  T+ S+  C  C  G ++   P +  + W
Sbjct:    2 AEAESQFTCAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCS-----YKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCY---APVDGRYMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSR-DKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPAGFLVSLDPFNYESDW 343          

Query:  227 DCEICGHLAKMFCSCCKHVFYCTREHQKKHW-KSHKEDCSALKKLPYRVERNGELGRHLVATTDIPAGTHFLNESPMVMGPRQMSKPVCLGCHKELVDLESVVKCSRCLWPLCSR-KCEDSKLH-EPECRVIKYGGSK--VNVESFGQVNMMYACITVLRALALQDGAQTIWKDYTKFESHLDKRMETEIYTKVNKEKVVYFIHYFLKLINKYSDLEILETC-GRLDTNCFEIKQNGMNLRAMYRVACIISHDCCPNTKHTFDPDHSINLFATTNIRKGSIISATYTQSIWNTMNRRAHLYMSKCFWCQCRRCRDPTEFGTYLSANSCNA--------CGGQVIPTQPLDNSAKWALQLEGN--------------EAELDK--LTMDD 585
            +C  CG     FCS C  V YC++EHQK HW + HK +C A K     V++ G  GR L+ T DI  G     ESP+ +GP+Q  +PVCLGC+K   ++     CS C WP+C   +CE + +H + EC ++     K  +++    +   +Y  +T LR L +++     W      ESH + R   E Y +VN+  +V FI   L+ I   + +E +  C   +D N FEI+ +  ++  +Y +  +++ +C PNT+++ D ++   + A T I KGS I++TYT+++  T+ RR  L  SK F C+C RC DPTE  ++ S   C A        C G V     L+ +A W  +  G               E E++K  LT+DD
Sbjct:   28 NCPECGKCVSQFCSGCHSVGYCSKEHQKNHWLQGHKNECCAYK----LVKKEGH-GRILIVTRDIEPGEVIFEESPITVGPKQFCQPVCLGCYK---NVNGTSICSGCNWPMCGNIECEKAPIHSKKECALLADCHLKPIIDLNKPEKDLPIYQFLTALRCLLVKEFRPDNWSILESMESHTELRKNEESY-RVNQVNIVKFI---LERIKYDTTVEDINKCIDVMDVNAFEIRSHEFSIAGLYPMTAMMNSNCSPNTQNSIDENYICRVMAITRIPKGSEINSTYTRTLSGTLYRRNQLKESKYFDCKCERCCDPTELNSHFSTLLCQAILPSISKTCKGFVYSENSLNTNASWICRACGAVMSHEEVTELTQKLEVEIEKEFLTIDD 404          

Query:  290 IPAGTHFLNESPMVMGPRQMSKPVCLGCHKELVDL-ESVVKCSRCLWPLCSRKCEDSKL--HEPECRVIKYG--GSKVNVESFGQVNMMYACITVLRALALQDGAQTIWKDYTKFESHLDKRMETEIYTKVNKEKVVYFIHYFLKLINKYSDLEILETCGRLDTNCFEIK--QNGMNLRAMYRVACIISHDCCPNTKHTFDPDHSINLFATTNIRKGSIISATYTQSIWNTMNRRAHLYMSKCFWCQCRRCRDPTEFGTYLSANSCNACG-GQVIPTQPLD--NSAKW 567
            +PA +H       V GP + S  VCL C+  + D  E +  CSRC  PLC  +C++S+L  H+PEC  +     G + ++     V++++  + VLR L L+D  +  W  +    SH+ +R ++E+  +  +          +++  +    E+L  CG LDTN FEI    +   ++A+Y++ C+  H+C P     F+ D S+ L A+ +++ G  I+ TYT S+W TM RR HL  SK F C C RCRDPTE G+++ A +C  CG G+++P  PL+  N   W
Sbjct:  420 LPASSH---PDCAVHGPCRDSSIVCLNCYGSIQDENEDISVCSRCGLPLCG-QCDESELNLHKPECHALSSSKRGKRTSLALLDNVSLLFEVVLVLRCLHLRDIPEN-WSHFLGLTSHVGERRDSELEARALEASEXXIRDIGIEIPRE----EVLNICGILDTNSFEIPLPSSPGTIQAIYKIGCLPEHNCIPTGHRCFESDLSLVLRASVDLKAGDHITITYTDSLWPTMERRTHLLYSKHFSCICERCRDPTEKGSFIGALNCLKCGVGRILPENPLEDKNETSW 698          

Query:  223 KPQGDCEICGHLAKMFCSCCKHVFYCTREHQKKHWKSHKEDCSALKKLPYRVERNGELGRHLVATTDIPAGTHFLNESPMVMGPRQMSKPVCLGCHKELVDLESVVKCSRCLWPLCSRKCEDSKLHEPECRVIKYGGSKVNVESFGQVNMMYACITVLRALALQDGAQTIWKDYTKFESHLDKRMETEIYT----KVNKEKVVYFIHYFLKLINKYSDLEIL-ETCGRLDTNC--FEIKQNGMNLRA--MYRVACIISHDCCPNTKHTFDPDHSINLFATTNIRKGSIISATYTQSIWNTMNRRAHLYMSKCFWCQCRRCRDPTEFGTYLSANSCNACGGQVIPTQPLDNSAKWA 568
            K + +C  CG+ A   C+ C+ V +C+    K     HK+D ++    P+ V+RN +LGRHLVAT DI A    L ESP+V+GP   S   CL C K L    S   C  C +P CS++C     H+ EC   +  G K +       N  Y+ IT LR L+LQ+     W   T  +  LD   + + YT       +E VV  I     L    +D + L    G +DTN     +  +G + +   +Y +   ++H C  NTK     D  I + A+ NI KG  I   Y +    T+ RR  +     F C C+RC DPTE G+YL A  C++C   V+P  PL+  + WA
Sbjct:    2 KIKAECFYCGNPATASCTTCELVSFCSEPSHKALHYGHKKDETSFC-FPFAVKRNSQLGRHLVATRDIKALEVILEESPLVIGPYISSNNQCLECFKTLD--TSPHSCISCNYPFCSQECSQGPWHKIECSAFQKYGHKRDEND----NDFYSIITTLRLLSLQESKPEFWN--TIMKDMLDHNSDIQEYTPEKWTSYEETVVKKIQ---SLTKGNADTDTLTRLIGVIDTNGADLNLPHDGKHGKGTGLYLIYSNLNHSCVCNTKTINFQDRRIEMRASVNISKGEQICNQYVRPNKCTLARRTTIKNKWYFDCCCKRCADPTECGSYLGALLCSSCKSVVLPINPLETESNWA 344          

Query:  200 SSTSKSQANADPNFEEGKPKSDGKPQGD--CEICG-------HLAKMFCSCCKHVFYCTREHQKKHWKSHKEDCSALKKLPYRVERNGELGRHLVATTDIPAGTHFLNESPMVMGPRQMSKPVCLGCHKELVDLESVVKCSRCLWPLCSRKCEDSKLHEPECRVIKYGGSKVNVESFGQVNMMYACITVLRALALQDGAQTIWKDYTKFESHLDKRMETEIYTKVNKEKVVYFIHYF----------LKLINKYSDLEILETCGRLDTNCFEIK----QNGMNLRAMYRVACIISHDCCPNTKHTFDPDHSINLFATTNIRKGSIISATYTQSIWNTMNRRAHLYMSKCFWCQCRRCRDPTEFGTYLSANSCNAC-GGQVIPTQPLDNSAKWALQLEGNEAELDKLTMDDIF-----ALRIITGTSDFKLREELLRQEKATKENFYKVAITWESAANV---QRTLAHP 635
            +++SK    A P       + D +   D  C  CG       HL    C  CK V+YC+ EH   H   H   C      P+ V+R+   GR++VA  DI      L+E P V+GP     P CL C + LVD      CS+C  P+C ++CE   LH PEC   +     +  E+        AC+T LR L ++      ++       H+++R+       +    ++ F+             +   N +   EI    G L TN  + +    + G    A+Y V C+I+H C  NT +   PD  + L +   I+KG  I   Y  S    + RR  +     F C+C+RC D TE GTY+S  +C  C  G ++P   L+  + W+      +  ++  T+ DI       +R I   +  +L E L   +K    N Y V     +  +V   + TL  P
Sbjct:   38 AASSKDSNGASPINGLTDTQDDVEVDNDMCCFFCGNEEEEDNHLT--LCPFCKIVYYCSEEHYIIH--RHSNRC-----FPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFR-LVD--GSYYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKENHYSSQ---ACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCN--NCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYAAKETLTRP 488          

Query:  228 CEICGHLAKMFCSCCKHVFYCTREHQKKHWKSHKEDCSALKKLPYRVE-RNGELGRHLVATTDIPAGTHFLNESPMVMGPR-QMSKPVCLGCHKELVDLESVVKCSRCLWPLCSRKCEDSKLHEPECRVIKYGGSKVNVESFGQVNMMYACITVLRALALQDGAQTIWKDYTKFESHLDKRMETEIYTKVNKEKVVYFIHYFLKLINKYSDLEILETCGRLDTNCFEI----------KQNGMNLRAMYRVACIISHDCCPNTKHTFDPDHSINLFATTNIRKGSIISATYTQSIWNTMNRRAHLYMSKCFWCQCRRCRDPTEFGTYLSANSCNAC 551
            CE C   AK+ C  C+ V+YC+REHQK+ W+ HK  C A     YR+E     LGR L    D+  G   ++  P V+GPR    KP CLGCH  L +  S+ +   C +PLCS +C      E EC+++         E     +     +T+LR   L+     I++     E H+D+   +    K  +E V+  +      ++   D E+    G   TN FE+          K+ G +++ +Y V  +++H C  N +   +    I+++A   I   + I+  Y   + +   R+  L  +K F C+C RC DPTE GT+ S+  C  C
Sbjct:   10 CEHCEAPAKLQCGACELVWYCSREHQKRKWRDHKMICIA-----YRIEDTQSALGRQLRTARDVKQGDLIISAPPCVIGPRLDYPKPSCLGCHVILDEKMSLCE-GGCEYPLCSSECHRKFHSEEECKLL---------EKIKSPDKRCEIVTILRFALLKKSNPRIYEKLILLEDHVDEIKASSTRWKNIEEGVLKHLKEIKSDLDIEEDQELERLVGIWITNSFELERTDQQLFGEKRAGESIQGLYDVPSLMNHSCVGNARLVINSGMYIDVYAAVPISNKAPITFNYISPLEDYDRRQKILKENKFFECKCERCEDPTELGTFSSSLLCQVC 330          

Query:  271 PYRVERNGELGRHLVATTDIPAGTHFLNESPMVMGPRQMSKPVCLGCHKELVDLESVVKCSRCLWPLCSRKC---------EDSKLHEPECRV-----IKYGGSKVNVESFGQVNMMYACITVLRALALQDGAQTIWKDYTKFESHLDKRMETEIYTKVNKEKVVYFIHYFLKLI-NKYSDLEILETCGRLDTNCFEI-------KQNGMNLRAMYRVACIISHDCCPNTKHTF---DPDHSINLFATTNIRKGSIISATYTQSIWNTMNRRAHLYMSKCFWCQCRRCRDPTEFGTYLSANSCNAC-GGQVIPTQPLDNSAKW 567
            PY++ RN  +GR++VAT DI  G   L E P+  GP   ++P+CLGC+  ++  +   +C  C +P+CS++C         E +++H    R+     +K+ GS+ +V         Y  I+++RAL L+      W       SH + R +   + K +  K +  I   +K+    Y  ++I+   G    N FEI        +    +R ++ +A + +H C  N  H F   +    + + A  +I++G  I+ +YT+ +   M R++ L + K F C C RCRDPTE  TY SA  C+ C  G VI     + ++ W
Sbjct:   30 PYKIIRNDSVGRYMVATRDIKPGETVLMEYPLTFGPGNPNEPICLGCYTPVLKNQHT-ECDGCGFPMCSKECSQILEHKDFECAEMHNMNFRLDSQNTLKWNGSQESV---------YNAISLMRALVLKKRDPARWNLIWMHMSHDEARQKDTFWQKKDA-KTLEHIKAMMKISPEDYDTIKII--LGIFLVNDFEICIPLEGSDEKSSLIRGIFALASMPNHSCVSNCYHNFTCREEGFKMTMKAVVDIKEGDEITHSYTEPLDPIMRRQSLLKIGKFFQCNCIRCRDPTEMSTYSSALICSKCKKGNVISKNCKNINSDW 339          

Query:  350 PECRVIKYGGSKVNVESFGQVNMMYACITVLRALALQDGAQTIWKDYTKFESHLDKRMETEIYT--KVNKEKVVYFIHYFLKLIN--------KYSDLEILETCGRLDTNCFEIKQNGMNLRAMYRVACIISHDCCPNTKHTFDPDHSINLFATTNIRKGSIISATYTQSIWNTMNRRAHLYMSKCFWCQCRRCRDPTEFGTYLS 544
            PE  +     ++V ++S+     +Y  I  LR L LQ  +   +      ESH ++R + +  T  K   EKV+  +   L ++          +SD  I    G L+TN  EI+     ++A+Y + C++ H CCPN + TFD  + + + A  NI+ G  +   YT S+W TM RR HLY++K FWC+C RC DP+E+G+ +S
Sbjct:   55 PEVVIPLQTEAEVVIDSYDSSCYLYDAIAPLRILLLQKTSPKKFGKIMSLESHFEERKKADPPTAWKRTIEKVIDVMKKTLGIMVFEVLYKQFDFSDDTIQRINGILETNAIEIRLAASEIQALYELTCLLEHSCCPNIRMTFDDKYHVTVRAGRNIKAGEHLCFMYTHSLWGTMARREHLYLNKFFWCKCLRCEDPSEYGSNIS 259          

Query:  281 GRHLVATTDIPAGTHFLNESPMVMGPRQM--SKPVCLGCHKELVDLESVVKCSRCLWPLCSRKCEDSKLHEPECRVIKYGGSKVNVESFGQVNMMYACITVLRALALQDGAQTIWKDYTKFESHLDKRMETEIYTKVNKEKVVYFIHYFLKLINKYSDLEILETCGRLDTNCFEIKQNGMNLRAMYRVACIISHDCCPNTKHTFDPDHSINLFATTNIRKGSIISATYTQSIWNTMNRRAHLYMSKCFWCQCRRCRDPTEFGTYLSANSCNAC-GGQVIPTQPL 561
            GR L A  +I   T    ESP V+GP  +  ++ VC+ C   +  LE+   C +C   +CS  C  S L E EC + +   +   ++S          I +LR +   D     WK   K E H +     + Y         Y  +   K+ ++ ++ E+L+    LD+N F I  N  +LR ++ V+  I+HDC PN +  FD    ++L +   I KG  IS +Y   + +T  RR  L  SK F+CQC+RC DPTE G++LS+  C  C  G+++ T  +
Sbjct:   25 GRGLFACHEISKDTVIYKESPFVVGPPIIGENRTVCITCSNTIHYLENF--CRKCSVEMCS-NC--SHLLEEECSLFEKHRNTQKLKSASN------WIAILRVILRTDELSIPWK---KLEDHSNNNYRMKFYKD-------YIANDLKKVHHEANESEVLKIASILDSNSFRI--NKHSLRGLFGVSSFINHDCNPNARVIFDRKGHLHLISKKTIEKGEEISISYVAPLLSTRERREKLMSSKFFYCQCKRCHDPTELGSHLSSLLCPKCQKGRIVQTNDI 285          

Query:  272 YRVERNGELGRHLVATTDIPAGTHFLNESPMVMGP---RQMSKPVCLGCHKELV-DLESVVKC-SRCLWPLCSRKCEDSKLHEPECRVIKYGGSKVNVESFGQVNMMYACITVLRALALQDGAQTIWKDYTKFESHLDKRMETEI------YTKVNKEKVVYFIHYFLKLINKYSDLEILETCGRLDTNCFEIKQNG----MNLRAMYRVACIISHDCCPNTKHTFDPDHSINLFATTNIRKGSIISATYTQSIWNTMNRRAHLYMSKCFWCQCRRCRDPTEFGTYLSANSC--NACGGQVIPTQPLDNSAKW 567
            +RV  +   GR + AT +I AG     E  +++GP   R M+   C  C++ +    +S   C + C  P+CS +C DS  H+ EC++ +       +ES          ++V+R   L + ++   K     ++++D+    E+      +    +E+ +  + YF + I  +            +TN FE + N     + +RA++ +A +++H C PN  H F+   +I + AT  I  G+ I+ +Y + +W+T+ R+  L M+K F C+C RC+DPTE GTYLSA  C    C G VIP Q       W
Sbjct:   44 WRVADSPISGRGIFATREIAAGEELFREHTLLVGPTAHRSMNLRTCTLCYRLIPGSTDSAALCPAGCGLPVCS-ECRDSTRHDLECKLFRKWKP---LESQRIEPRALRILSVVRCFFLDEASR---KLLYAMQANMDRYYMQEVQRAADCFEHFPREQDM--LDYFYRTICAF------------NTNAFESRSNVDGHEVLVRALFPLAGLLNHQCTPNAAHHFENGETIVVCATERIPAGAEITMSYAKLLWSTLARKIFLGMTKHFICKCVRCQDPTENGTYLSALFCREQGCRGLVIPVQTRTLQPDW 335          

Query:  281 GRHLVATTDIPAGTHFLNESPMVMGP--RQMSKPVCLGCHKELVDLESVVKCSRCLWPLCSRKCEDSKLHEPECRVIKYGGSK-VNVESFGQVN-MMYACITVLRALALQDGAQTIWKDYTKFESHLDKRMETEIYTKVNKEKV--VYFIHYFLKLINKYSDLEILETCGRLDTNCFE--IKQNGMN--LRAMYRVACIISHDCCPNTKHTFDPDHSINLFATTNIRKGSIISATYTQSIWNTMNRRAHLYMSKCFWCQCRRCRDPTEFGTYLSANSC--NACGGQVIPTQPLDNSAKW 567
            GR + AT DI AG     E  +V GP  R+     C+ CH+ L     + +  RC  P+C   C DS+ H+ EC   +    K V+ E   QVN M    +T +R   L            K + HL   M+        +E +        F      + D ++    G L+TN FE   +  G    LR ++ +  I++H+C PN  H F+      + A  +I KG  I+ TYT+ +W  + R   L M+K F C C RC D TE GTYLSA  C    C G VIP Q       W
Sbjct:   66 GRGVFATRDIAAGELIFQERALVTGPTARKGQLSSCICCHETLPQTGFLCR-HRCTLPVCE-TCSDSEEHQAECEHFRRWQPKDVDAEQ-EQVNPMSLRILTAVRVFHL-----------GKEQRHLVDAMQANAERAYRREIIQAAQCFRNFPTTDRVFMD-QLFRIVGVLNTNAFEAPCRSGGHETLLRGLFPLTAIMNHECTPNASHYFENGRLAVVRAARDIPKGGEITTTYTKILWGNLTRNIFLKMTKHFACDCVRCHDNTENGTYLSALFCREQGCRGLVIPVQTRTLQPDW 349          

Query:  271 PYRVER--NGELGRHLVATTDIPAGTHFLNESPMVMGPRQMSKPVCLGCHKELVDLESVVKCSRC-LWPLCSRKCEDSKL--HEPECRVIKYGGSKV---NVESFGQVNMMYACITVLRALALQDGA----QTIWKDYTKFESHLDKRMETEIYTKVNKEKVVYFIHYFLKLINKYSDL----EILETCGRLDTNCF-----EIKQNGMNLRAMYRVACIISHDCCPNTKHTFDPDHSINLFATTNIRKGSIISATYTQSIWNTMNRRAHLYMSKCFWCQCRRCR 534
            P +VE+    + G  L A T +  G       P+     + S+ V   C + L+  E +++CS+C +   CS KC+      H+ EC+ +K    +    +V   G+V              L DGA    + ++  Y   ES+++K   TE   +  ++ V+ F H+  + I   S L    ++ E   ++  N F     E+++ G+ L   Y    +++H C PN    F+  H + L A  +I  G  ++  Y   +  +  RR  L    CF C C RC+
Sbjct:    3 PLKVEKFATAKRGNGLRAVTPLRPGELLFRSDPLAYTVCKGSRGVV--CDRCLLGKEKLMRCSQCRVAKYCSAKCQKKAWPDHKRECKCLKSCKPRYPPDSVRLLGRV-----------VFKLMDGAPSESEKLYSFY-DLESNINKL--TEDKKEGLRQLVMTFQHFMREEIQDASQLPPAFDLFEAFAKVICNSFTICNAEMQEVGVGL---YPSISLLNHSCDPNCSIVFNGPHLL-LRAVRDIEVGEELTICYLDMLMTSEERRKQLRDQYCFECDCFRCQ 267          

Query:  281 GRHLVATTDIPAGTHFLNESPMVMGPRQMS-KPVCLGCHKELVDLESVVKCSRC--LWPLCSRKCEDS--KLHEPECRVIKYGGSKVNVESFGQVNMMYACITVLRALALQDGAQ-------TIWKDYTKFE---SHLDKRMETEIYTKVNKEKVVYFIHYFLKLINKYSDL-EILETCGRLDTNCF-----EIKQNGMNLRAMYRVACIISHDCCPNTKHTFDPDHSINLFATTNIRKGSIISATYTQSIWNTMNRRAHLYMSKCFWCQCRRCRD 535
            GR L    D   G   L++ P +  P   S +  C GC K      ++ KCS C  +W  C   C+ S  KLH  EC+ +    +++  E    V      I ++  L ++   Q       T   +Y+  E   SH+ +  E ++        +V  I  F  +     DL EI E   +   N       E++  G+ L   + +  II+H C PN    F+   ++ + A  NI K S I+ +Y ++  +T+ R+  L     F CQC RC +
Sbjct:   22 GRSLFTARDFRPGEVILSQKPYICVPNNTSSESRCDGCFKT----NNLKKCSACQVVW-YCGSSCQKSEWKLHRDECKAL----TRLEKEKRKFVT---PTIRLMVRLYIKRNLQNEKVLPITTTDNYSLVEALVSHMSEIDEKQMLLYAQMANLVNLILQFPSV-----DLREIAENFSKFSCNAHSICDSELRPQGIGL---FPLVSIINHSCSPNAVLVFEEQMAV-VRAMDNISKDSEITISYIETAGSTLTRQKSLKEQYLFHCQCARCSN 276          

Query:  277 NGELGRHLVATTDI-PAGTHFLNESPMVMGPRQMSKPV-----CLGCHKELVDLES--VVK----CSRCLWPLCSRKCEDSKLHEPECRVIKYGGSK---------VNVESFGQVNMMYAC--ITVLRALALQDGAQTIWKDYTKFES-----------------HLDKRMETEIYTKVN--------KEKVVYFIHYFLKLINKYSDLEILETCGRLDTNCFEIKQNGMNLRAMYRVACIISHDCCPNTKHTFDPDHSINLFATTNIRKGSIISATYTQSIWNTMNRRAHLYMSKCFWCQCRRC 533
            + E G+ LVAT DI   G  F  + P+ + P+   +P+     C G       L S  ++K    C+ C    CS++C+  KL      V+K+  S+         +  E+F     + A   + V+ A  +      +WK +T   S                   D     ++Y  V+         +    F   F K    Y D   L       T  F + Q    +  +Y +   I+H C PN ++  +P H I L+A  +I+KG  +  TY   +     RR  L ++  F C C RC
Sbjct:  119 DTEFGKGLVATDDIRKGGLVFHEQLPLTVIPQLDKQPLVSRGKCCGLCSAFTTLSSQLIIKNNLDCNMCNTIWCSKQCK--KLDTTH-SVLKHATSRNSLCNSSNWIKFENFCLQESLVAAYAVGVIYARHVMQPTSNLWKLFTSLCSVSQRVRWQASDSINVGGTFDASCNGKLYADVSAPNMETQWSDAFEMFAKSFPKCDMDYEDFLNL-------TGTFNLNQI---MGQVYPLVAHINHSCEPNVRYELEPKHGIKLYARKDIKKGEQLRLTYVNPLHGVTLRRRELRVNYGFLCHCPRC 410          

Query:  221 DGKPQGDCEICGHLAKMFCSCCKHVFYCTREHQKKHWKSHKEDCSALKKLPYRVERNGELGRHLVATTDIPAGTHFLNESPMVMGPRQMSKPVCLGCHKELVDLESVVKCSRCLWPLCSRKCEDSKLHEPECRVIKYGGSKVNVESFGQVNMMYACITVLRALALQDGAQTIWKDYTKFESHLDKRMETEIYTKVNKEKVVYFIHYFLKLINKYSDLEILETCGRLDTNCFEIKQNGMNLRAMYRVACIISHDCCPNTKHTFDPDHSINLFATTNIRKGSIISATYTQSIWNTMNRRAHLYMSKCFWCQCRRCRDPTEFGTYLSANSCNACGG-----------QVIPTQPLDNSAKW 567
            D  P GDC +CG LAK  CS CKHVFYCTREHQKK W SHK+ C    KLPYRVER+ +LGR L AT D+  G   L ESPMV+GPRQ++KPVCLGCHKE+     ++KC RC WP+CS KC+DS  H+PECR  K  GSKVNVE F Q NMMYACITV+RALALQDG + +W+DY KF+SHLD+R++T IY KVNKEKVV+F+H++L  I +YSDLEILE  G+LDTNCFEI+QNG NLRAMYR ACIISHDC PNT+HTF PD+SIN++ T  I KGSIISATYT ++W T+ RR HL MSKCFWC CRRCRDPTE G+YLSA  C+ C G            + PT PL+  + W
Sbjct:  499 DQVPCGDCVVCGRLAKAACSGCKHVFYCTREHQKKDWTSHKDSCKEFFKLPYRVERSKKLGRFLAATKDLAEGELILQESPMVIGPRQLTKPVCLGCHKEIASSSEMIKCIRCNWPVCSLKCQDSPQHDPECRATKAAGSKVNVEVFNQTNMMYACITVIRALALQDGPKKVWEDYVKFDSHLDERIKTPIYNKVNKEKVVFFMHHYLG-IKRYSDLEILEASGKLDTNCFEIRQNGQNLRAMYRTACIISHDCTPNTRHTFSPDNSINIYTTRKIEKGSIISATYTNTLWPTLQRREHLNMSKCFWCSCRRCRDPTELGSYLSAIRCSRCLGFRDNVQNNDLQYITPTNPLNPESLW 855          

Query:  221 DGKPQGDCEICGHLAKMFCSCCKHVFYCTREHQKKHWKSHKEDCSALKKLPYRVERNGELGRHLVATTDIPAGTHFLNESPMVMGPRQMSKPVCLGCHKELVDLESVVKCSRCLWPLCSRKCEDSKLHEPECRVIKYGGSKVNVESFGQVNMMYACITVLRALALQDGAQTIWKDYTKFESHLDKRMETEIYTKVNKEKVVYFIHYFLKLINKYSDLEILETCGRLDTNCFEIKQNGMNLRAMYRVACIISHDCCPNTKHTFDPDHSINLFATTNIRKGSIISATYTQSIWNTMNRRAHLYMSKCFWCQCRRCRDPTEFGTYLSANSCNACGG-----------QVIPTQPLDNSAKW 567
            D  P GDC +CG LAK  CS CKHVFYCTREHQKK W SHK+ C    KLPYRVER+ +LGR L AT D+  G   L ESPMV+GPRQ++KPVCLGCHKE+     ++KC RC WP+CS KC+DS  H+PECR  K  GSKVNVE F Q NMMYACITV+RALALQDG + +W+DY KF+SHLD+R++T IY KVNKEKVV+F+H++L  I +YSDLEILE  G+LDTNCFEI+QNG NLRAMYR ACIISHDC PNT+HTF PD+SIN++ T  I KGSIISATYT ++W T+ RR HL MSKCFWC CRRCRDPTE G+YLSA  C+ C G            + PT PL+  + W
Sbjct:  503 DQVPCGDCVVCGRLAKAACSGCKHVFYCTREHQKKDWTSHKDSCKEFFKLPYRVERSKKLGRFLAATKDLAEGELILQESPMVIGPRQLTKPVCLGCHKEIASSSEMIKCIRCNWPVCSLKCQDSPQHDPECRATKAAGSKVNVEVFNQTNMMYACITVIRALALQDGPKKVWEDYVKFDSHLDERIKTPIYNKVNKEKVVFFMHHYLG-IKRYSDLEILEASGKLDTNCFEIRQNGQNLRAMYRTACIISHDCTPNTRHTFSPDNSINIYTTRKIEKGSIISATYTNTLWPTLQRREHLNMSKCFWCSCRRCRDPTELGSYLSAIRCSRCLGFRDNVQNNDLQYITPTNPLNPESLW 859          

Query:  221 DGKPQGDCEICGHLAKMFCSCCKHVFYCTREHQKKHWKSHKEDCSALKKLPYRVERNGELGRHLVATTDIPAGTHFLNESPMVMGPRQMSKPVCLGCHKELVDLESVVKCSRCLWPLCSRKCEDSKLHEPECRVIKYGGSKVNVESFGQVNMMYACITVLRALALQDGAQTIWKDYTKFESHLDKRMETEIYTKVNKEKVVYFIHYFLKLINKYSDLEILETCGRLDTNCFEIKQNGMNLRAMYRVACIISHDCCPNTKHTFDPDHSINLFATTNIRKGSIISATYTQSIWNTMNRRAHLYMSKCFWCQCRRCRDPTEFGTYLSANSCNACGG-----------QVIPTQPLDNSAKW 567
            D  P GDC +CG LAK  CS CKHVFYCTREHQKK W SHK+ C    KLPYRVER+ +LGR L AT D+  G   L ESPMV+GPRQ++KPVCLGCHKE+     ++KC RC WP+CS KC+DS  H+PECR  K  GSKVNVE F Q NMMYACITV+RALALQDG + +W+DY KF+SHLD+R++T IY KVNKEKVV+F+H++L  I +YSDLEILE  G+LDTNCFEI+QNG NLRAMYR ACIISHDC PNT+HTF PD+SIN++ T  I KGSIISATYT ++W T+ RR HL MSKCFWC CRRCRDPTE G+YLSA  C+ C G            + PT PL+  + W
Sbjct:  503 DQVPCGDCVVCGRLAKAACSGCKHVFYCTREHQKKDWTSHKDSCKEFFKLPYRVERSKKLGRFLAATKDLAEGELILQESPMVIGPRQLTKPVCLGCHKEIASSSEMIKCIRCNWPVCSLKCQDSPQHDPECRATKAAGSKVNVEVFNQTNMMYACITVIRALALQDGPKKVWEDYVKFDSHLDERIKTPIYNKVNKEKVVFFMHHYLG-IKRYSDLEILEASGKLDTNCFEIRQNGQNLRAMYRTACIISHDCTPNTRHTFSPDNSINIYTTRKIEKGSIISATYTNTLWPTLQRREHLNMSKCFWCSCRRCRDPTELGSYLSAIRCSRCLGFRDNVQNNDLQYITPTNPLNPESLW 859          

Query:  221 DGKPQGDCEICGHLAKMFCSCCKHVFYCTREHQKKHWKSHKEDCSALKKLPYRVERNGELGRHLVATTDIPAGTHFLNESPMVMGPRQMSKPVCLGCHKELVDLESVVKCSRCLWPLCSRKCEDSKLHEPECRVIKYGGSKVNVESFGQVNMMYACITVLRALALQDGAQTIWKDYTKFESHLDKRMETEIYTKVNKEKVVYFIHYFLKLINKYSDLEILETCGRLDTNCFEIKQNGMNLRAMYRVACIISHDCCPNTKHTFDPDHSINLFATTNIRKGSIISATYTQSIWNTMNRRA 518
            D  P GDC +CG LAK  CS CKHVFYCTREHQKK W SHK+ C    KLPYRVER+ +LGR L AT D+  G   L ESPMV+GPRQ++KPVCLGCHKE+     ++KC RC WP+CS KC+DS  H+PECR  K  GSKVNVE F Q NMMYACITV+RALALQDG + +W+DY KF+SHLD+R++T IY KVNKEKVV+F+H++L  I +YSDLEILE  G+LDTNCFEI+QNG NLRAMYR ACIISHDC PNT+HTF PD+SIN++ T  I KGSIIS +Y  + +   N  A
Sbjct:  503 DQVPCGDCVVCGRLAKAACSGCKHVFYCTREHQKKDWTSHKDSCKEFFKLPYRVERSKKLGRFLAATKDLAEGELILQESPMVIGPRQLTKPVCLGCHKEIASSSEMIKCIRCNWPVCSLKCQDSPQHDPECRATKAAGSKVNVEVFNQTNMMYACITVIRALALQDGPKKVWEDYVKFDSHLDERIKTPIYNKVNKEKVVFFMHHYLG-IKRYSDLEILEASGKLDTNCFEIRQNGQNLRAMYRTACIISHDCTPNTRHTFSPDNSINIYTTRKIEKGSIISTSYIDNNFRDSNISA 799          

Query:  228 CEICGHLAKMFCSCCKHVFYCTREHQKKHWK-SHKEDCSALKKLPYRVERNGELGRHLVATTDIPAGTHFLNESPMVMGPRQMSKPVCLGCHKEL---VDLESVVKCSRCLWPLCSRKCEDSKLHEPECRVIKYGGSKVNVESFGQV---NMMYACITVLRALALQDGAQTIWKDYTKFESHLDKRMETEIYTKVNKEKVVYFIHYFLKLINKYSDLEILETCGRLDTNCFEIKQN--GMNLRAMYRVACIISHDCCPNTKHTFDPDHSINLFATTNIRKGSIISATYTQSIWNTMNRRAHLYMSKCFWCQCRRCRDPTEFGTYLSANSCNACG-GQVIPTQPLDNSAKWALQLEGNEAELDKLTMDDIFALRIITGTSDFKLREELLRQEKATKENFYKVAITWESAANVQRTLAHPHEVSVAAVSSYKKNKSYHNPKPEHKSKANNYGHCHRCGNKGEHPLRECYAKDAVCQKCQKIGHITS---ACYTGQYRPENQRSHSRGRSGSRPLDRSRPRFSNRVDIKSTLIEETFEENLEHLKEAFAILQVEPDEKDKLGEQMKGLAKALE 784
            C +CG  A + C  CK VFYC +EHQK HWK  HK +C       Y + RN  LGRHL A+ DI  G   L ESP++ GP+  S P+CLGCH+ L   V   +  KC +C WPLC   CE S+ H  EC+++     +  ++  GQV      Y  I  LR L ++      ++ +++ E HL++R +T +Y  V +  +V F+   L +    S+ E+L     LDTN FEI+QN  G  +RA+Y  A + SHDC  N++HTFD +  I   A T I KG IIS +YTQ +W+T+ RR+HL  +KCF C CRRC DPTE  T+  A +C+ C  G++I T P+DNSA W  QL  ++    ++ +             +  ++ E+   +K + + F +    +    + + T  H  +V  A    Y  +   HN     +                         K  +CQ+  +I  +     + + G    + Q +          + +++  F N +  +    +E   E++  LKEA  I+++EPD K  L E+ + LAK LE
Sbjct:    7 CAVCGVSASLKCMACKQVFYCGKEHQKIHWKKGHKAECKC-----YEIARNDVLGRHLRASRDIKCGEIILRESPLIYGPKVASAPLCLGCHRTLSTPVGGSNFYKCRKCSWPLCGPDCEHSQHHLHECQLMASRNFRAKIDYSGQVGKKESAYCVILPLRCLLMKASQPADFERFSELEDHLNERKDTPLYN-VLRANLVTFVKTILGM--HESEEEVLRVAAILDTNAFEIRQNNLGRKVRAIYPSASMFSHDCISNSRHTFDDNMQIVFIAKTPIAKGDIISTSYTQPLWSTIMRRSHLLQAKCFECTCRRCLDPTELNTFTGAITCSRCKVGKIISTNPMDNSAIWKCQLCPHKLSAKQINL------------GNQAIQNEIDSLDKTSAKAFEEFLFRYRDTLHEKNT--HILQVKYALTQLYDFSMIEHNDAALKR-------------------------KLELCQELLEIAELLDGGWSIFRGNLILDLQEAM---------VVQAKREFLNGLLTREA-TQEKLLESMNLLKEALEIMKLEPDMKQMLNERTQLLAKELE 519          

Query:  228 CEICGHLAKMFCSCCKHVFYCTREHQKKHWKSHKEDCSALKKLPYRVERNGELGRHLVATTDIPAGTHFLNESPMVMGPRQMSKPVCLGCHKELV-------DLESVVKCSRCLWPLCSRKCEDSKLHEPECRVI--KYGGSKVNVESFGQVNMMYACITVLRALALQDGAQTIWKDYTKFESHLDKRMETEIYTKVNKEKVVYFIHYFLKLINKYSDLEILETCGRLDTNCFEIKQNGMN--LRAMYRVACIISHDCCPNTKHTF-DPDHSINLFATTNIRKGSIISATYTQSIWNTMNRRAHLYMSKCFWCQCRRCRDPTEFGTYLSANSCNACGGQVIPTQPLDNSAKW 567
            C  CG  AK+ CS C  ++YC REHQKKHWK+HK +C+      +R+E +  +GR++VA  DI  G   L E P+V+GP+  S PVCLGC++ L        D     KCS+C WPLC+ +CEDS  H  EC+++  +   S +  +   +    Y CIT LR L L    Q  ++  +  +SHLD+R+ T +Y K+ K  +V FI   L L  ++ +  IL   G LDTN FEI++N  N  +R +Y    ++SH+C PNTKH F   D  ++L AT +I+K  IISATYTQ++W T++RRAHL MSKCF C C RC D TEF T+LSA  C+ C   VI T+PL+  A W
Sbjct:    5 CATCGEEAKLLCSGCHSLYYCGREHQKKHWKTHKPECTT-----FRLEYSPTMGRYVVANRDIKQGEIILKEKPIVLGPKIASLPVCLGCNRRLKATAMDDDDPLEYYKCSKCGWPLCAPRCEDSPNHRDECKLMSERNYRSPIQYQDSPKKESSYCCITPLRCLLL---PQKEFQRLSGLQSHLDERINTPLY-KILKTNLVMFIREVLGL-KQFDERTILNVAGILDTNAFEIRRNMGNVKIRGLYPRTAMLSHNCKPNTKHVFAGEDFELSLMATVDIKKDEIISATYTQTLWPTLDRRAHLKMSKCFDCSCERCADATEFNTFLSAIKCSKCKNYVISTEPLNRLADW 346          

Query:  226 GDCEICGHLAKMFCSCCKHVFYCTREHQKKHWKSHKEDCSALKKLPYRVERNGELGRHLVATTDIPAGTHFLNESPMVMGPRQMSKPVCLGCHKEL--VDLESVVKCSRCLWPLCSRKCEDSKLHEPECRVIKYGGSKVNVE-SFGQVNMMYACITVLRALALQDGAQTIWKDYTKFESHLDKRMETEIYTKVNKEKVVYFIHYFLKLINKYSDLEILETCGRLDTNCFEIKQN--GMNLRAMYRVACIISHDCCPNTKHTF-DPDHSINLFATTNIRKGSIISATYTQSIWNTMNRRAHLYMSKCFWCQCRRCRDPTEFGTYLSANSCNAC---GG----QVIPTQPLDNSAKW 567
            G C +C  +A   CS C  VFYC+REHQK+HWK HK  C+     PY+VE +  LG H+VAT DI  G   + E P+V+GP+ +S P+CLGC + +  ++ E V KCS C WPLC   CE S  H PEC ++K  G + ++     +    Y  IT LR L L+   Q+ ++   K +SHL +R +T +Y  + K  VV F+   L +  ++S+  IL     LDTN FEI+++   + +R +Y  A ++SHDC PNTKH F  P +++ L +T  I+KG II  TYTQ++W T+ RRAHL  SKCF C C RC D TE GTY+ A +C+ C   GG    ++I T PL+ SA W
Sbjct:    3 GSCAVCQAVATQCCSSCHLVFYCSREHQKQHWKIHKTQCT-----PYKVEVSERLGHHVVATRDIQQGEVIIEEEPIVLGPKVLSLPLCLGCGRRIKVIEGEEVYKCSGCGWPLCGSHCETSPFHVPECNLMKERGFRADINLKEDKKEAAYCSITPLRCLLLKKHDQSKYEGIVKMQSHLKERRDTPLYN-IFKNNVVGFLRNALGM-TEFSEETILRITAILDTNSFEIRRSEGDIKVRGLYSKAAMLSHDCKPNTKHFFRGPKYTLKLVSTVPIKKGEIICVTYTQTLWGTLERRAHLKQSKCFDCTCLRCSDATELGTYIGAINCSQCKKSGGKRNDKLISTSPLEPSAPW 350          

Query:  226 GDCEICGHLAKMFCSCCKHVFYCTREHQKKHWKSHKEDCSALKKLPYRVERNGELGRHLVATTDIPAGTHFLNESPMVMGPRQMSKPVCLGCHKEL--VDLESVVKCSRCLWPLCSRKCEDSKLHEPECRVIKYGGSKVNVE-SFGQVNMMYACITVLRALALQDGAQTIWKDYTKFESHLDKRMETEIYTKVNKEKVVYFIHYFLKLINKYSDLEILETCGRLDTNCFEIKQN--GMNLRAMYRVACIISHDCCPNTKHTF-DPDHSINLFATTNIRKGSIISATYTQSIWNTMNRRAHLYMSKCFWCQCRRCRDPTEFGTYLSANSCNAC---GG----QVIPTQPLDNSAKW 567
            G C +C  +A   CS C  VFYC+REHQK+HWK HK  C+     PY+VE +  LG H+VAT DI  G   + E P+V+GP+ +S P+CLGC + +  ++ E V KCS C WPLC   CE S  H PEC ++K  G + ++     +    Y  IT LR L L+   Q+ ++   K +SHL +R +T +Y  + K  VV F+   L +  ++S+  IL     LDTN FEI+++   + +R +Y  A ++SHDC PNTKH F  P +++ L +T  I+KG II  TYTQ++W T+ RRAHL  SKCF C C RC D TE GTY+ A +C+ C   GG    ++I T PL+ SA W
Sbjct:   15 GSCAVCQAVATQCCSSCHLVFYCSREHQKQHWKIHKTQCT-----PYKVEVSERLGHHVVATRDIQQGEVIIEEEPIVLGPKVLSLPLCLGCGRRIKVIEGEEVYKCSGCGWPLCGSHCETSPFHVPECNLMKERGFRADINLKEDKKEAAYCSITPLRCLLLKKHDQSKYEGIVKMQSHLKERRDTPLYN-IFKNNVVGFLRNALGM-TEFSEETILRITAILDTNSFEIRRSEGDIKVRGLYSKAAMLSHDCKPNTKHFFRGPKYTLKLVSTVPIKKGEIICVTYTQTLWGTLERRAHLKQSKCFDCTCLRCSDATELGTYIGAINCSQCKKSGGKRNDKLISTSPLEPSAPW 362          

Query:  226 GDCEICGHLAKMFCSCCKHVFYCTREHQKKHWK-SHKEDCSALKKLPYRVERNGELGRHLVATTDIPAGTHFLNESPMVMGPRQMSKPVCLGCHKELVD----LESVVKCSRCLWPLCSRKCEDSKLHEPECRVIKYGGSKVNV------ESFGQVNMMYACITVLRALALQDGAQTIWKDYTKFESHLDKRMETEIYTKVNKEKVVYFIHYFLKLINKYSDLEILETCGRLDTNCFEIKQN--GMNLRAMYRVACIISHDCCPNTKHTFDPDHSINLFATTNIRKGSIISATYTQSIWNTMNRRAHLYMSKCFWCQCRRCRDPTEFGTYLSANSCNACG-GQVIPTQPLDNSAKWALQLEGNEAELDKLTMDDIFALRIITGTSDFKLREELLRQEKATKENFYKVAITWESAANVQRTLAHPHEVSVAAVSSYKKNKSYHNPKPEHKSKANNYGHCHRCGNKGEHPLRECYAKDAVCQKCQKIGHITS---ACYTGQYRPENQRSHSRGRSGSRPLDRSRPRFSNRVDIKSTLIEETFEENLEHLKEAFAILQVEPDEKDKLGEQMKGLAKALE 784
            G+C +CG  A   C  C++V YC +EHQ  HWK  HK +C       Y +  N  LGRHL AT DI  G  FL E P + GP+  S P CLGCH+ L +     ++  KCSRC WPLC  +CE+S  H  EC ++     K  +      E  G+    Y  I  LR + L++     +  + + E HL++RM T +Y ++    ++ FI   +   +++SD E+L    RLDTN FE++Q   G  LRA+Y  A +ISHDC  N +HTFD    I   A   I KG II+ +YTQ + +T+ RR HL  +KCF C C RC+DP E GT+  A  C+ C  G++I T PLDN A W  QL  +E    ++   +   L+ I   +    R                    +E   +  R   H     V  V  Y   + Y N  P  +    N     R              K  +CQ+  ++  I     + + G    + Q +          + +++  F + +  K+ + +E   E +E LKEA  I+++EPD ++ L E+ + LAK LE
Sbjct:    5 GNCAVCGVAASQKCGGCRNVVYCGKEHQIIHWKKGHKAECKC-----YEIATNDILGRHLRATRDIKKGEIFLREKPFIYGPKVASAPTCLGCHRSLPNPVPPQKNFYKCSRCSWPLCGPQCENSAHHIDECELMSARKFKAKIDFDPTKEGTGKKESAYCVILPLRCILLRNKNPEAFARFAQLEDHLNERMNTPLY-RILSANLLTFIKTIMGF-SEWSDDEVLRVAARLDTNTFEVRQAAAGQKLRAIYTNAAMISHDCVSNARHTFDDQMQILFIAKQKIAKGEIIATSYTQPLKSTLMRRQHLSQAKCFECTCARCKDPEELGTFAGAILCSRCKVGKIISTDPLDNGALWKCQLCPHEIPAKQINWGNGAMLKEIESLNKMSPR-------------------AFEEFLHRYRDTLHEKNTHVLQV-KYALTQLYGNA-PGFQMHEMNDAAVKR--------------KVELCQELLEVAEILDGGWSIFRGNLLLDLQEA---------LVVQAKREFESGLLTKANV-QEKLTEAMELLKEAVEIMKLEPDMQEALTERTQQLAKELE 528          

Query:  226 GDCEICGHLAKMFCSCCKHVFYCTREHQKKHWKSHKEDCSALKKLPYRVERNGELGRHLVATTDIPAGTHFLNESPMVMGPRQMSKPVCLGCHKELV--DLESVVKCSRCLWPLCSRKCEDSKLHEPECRVIKYGGSKVNVESFGQVNMMYACITVLRALALQDGAQTIWKDYTKFESHLDKRMETEIYTKVNKEKVVYFIHYFLKLINKYSDLEILETCGRLDTNCFEIKQNG--MNLRAMYRVACIISHDCCPNTKHTFD-PDHSINLFATTNIRKGSIISATYTQSIWNTMNRRAHLYMSKCFWCQCRRCRDPTEFGTYLSANSCNAC---GGQ----VIPTQPLDNSAKWALQL 571
            G C +C   A   CS C  VFYC+R HQ++HWK HK  C+     PY++  + +LG H+VAT DI  G   + E P V+GP+ +S P+CLGC + L   D     KC  C WPLC   CE S LH PEC ++K  G + ++++  +    Y  IT LR L LQ      ++   K +SHL++R  T +Y  + K  +V F+   L +  ++S+  IL+    LDTN FEI+++   + +R +Y  A ++SHDC PNTKH F  P++++ L +T  I+KG II  TYTQ++W T+ RR HL  SKCF C C RC D TE GTYL + +C+ C   GG+    +I T PL++S+ W  Q+
Sbjct:    3 GPCAVCQAGATQCCSGCHSVFYCSRNHQRQHWKFHKTRCA-----PYKLSVSAQLGYHVVATRDIRQGETIMKEDPTVLGPKVVSLPLCLGCGRRLRVPDGTETYKCRSCGWPLCGAHCEMSPLHVPECSLMKERGFRASIQAEDKKEAAYCSITPLRCLLLQKRDPQKYEAILKLQSHLEERRNTTLY-NIFKNNIVGFLRNALGM-TEFSEETILKVAAILDTNSFEIRRSDGDIKIRGLYPKAAMLSHDCKPNTKHVFTGPNYTLELVSTVPIKKGEIICVTYTQTLWGTLARREHLKQSKCFDCNCERCSDETELGTYLGSINCSQCKKSGGKKSSMIISTNPLESSSPWKCQV 353