EMLSAG00000000123, EMLSAG00000000123-682889 (gene) Lepeophtheirus salmonis
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Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of EMLSAG00000000123 vs. GO
Match: - (symbol:VAV1 "Uncharacterized protein" species:9615 "Canis lupus familiaris" [GO:0006909 "phagocytosis" evidence=IEA] [GO:0006955 "immune response" evidence=IEA] [GO:0007229 "integrin-mediated signaling pathway" evidence=IEA] [GO:0030676 "Rac guanyl-nucleotide exchange factor activity" evidence=IEA] [GO:0035556 "intracellular signal transduction" evidence=IEA] [GO:0042110 "T cell activation" evidence=IEA] [GO:0045785 "positive regulation of cell adhesion" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] Pfam:PF00018 Pfam:PF00017 Pfam:PF00169 InterPro:IPR000219 InterPro:IPR000980 InterPro:IPR001331 InterPro:IPR001452 InterPro:IPR001715 InterPro:IPR002219 InterPro:IPR028530 Pfam:PF00130 Pfam:PF00621 PRINTS:PR00401 PRINTS:PR00452 PROSITE:PS00479 PROSITE:PS00741 PROSITE:PS50001 PROSITE:PS50002 PROSITE:PS50010 PROSITE:PS50021 PROSITE:PS50081 SMART:SM00033 SMART:SM00109 SMART:SM00252 SMART:SM00325 SMART:SM00326 InterPro:IPR001849 GO:GO:0007264 GO:GO:0006955 GO:GO:0006909 Gene3D:2.30.29.30 Gene3D:3.30.505.10 InterPro:IPR011993 SMART:SM00233 PROSITE:PS50003 GO:GO:0046872 SUPFAM:SSF50044 Gene3D:1.20.900.10 SUPFAM:SSF48065 GO:GO:0042110 Gene3D:1.10.418.10 SUPFAM:SSF47576 GO:GO:0007229 GO:GO:0045785 GO:GO:0032314 GO:GO:0030676 InterPro:IPR011511 Pfam:PF07653 InterPro:IPR003096 PRINTS:PR00888 InterPro:IPR022613 Pfam:PF11971 KO:K05730 OrthoDB:EOG73FQKZ TreeFam:TF316171 PANTHER:PTHR22826:SF53 GeneTree:ENSGT00740000115307 CTD:7409 OMA:SHRVTWD EMBL:AAEX03012488 EMBL:AAEX03012484 EMBL:AAEX03012485 EMBL:AAEX03012486 EMBL:AAEX03012487 RefSeq:XP_542134.2 ProteinModelPortal:E2RGT8 Ensembl:ENSCAFT00000029523 GeneID:485016 KEGG:cfa:485016 NextBio:20859080 Uniprot:E2RGT8) HSP 1 Score: 176.792 bits (447), Expect = 3.066e-45 Identity = 181/729 (24.83%), Postives = 302/729 (41.43%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDA--ETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGLNIK-----GSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIH----------------------CLGKIDVVEKTIKLM---QLP---RGAQLSDFGRLRKAGELTAEN-SYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPLFHRIV-----PHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDY-PCLEVGSTNSNA------------SSINNNGLTKCDSVTLPTVINEPLERSESTLSLSPD-----SKQPSADRVSKLQRETEEELINIPVER--------------QSWFAGDLNPKTASVRLQSLPVGTFLVRKR 678
M LW++C WL +V+PP H++ T +++ + +RDGVLLCQL+++L P ++++ V SQ F+C NI FL F L E FE DL+ Q+ G VI TLSALS + + FP +E+ + +E+IYS + + D E E +YD + + + YE++ +T P + + KR + E+ TE+KY + L ++ F L L +D E+IF +++L+R+HT L + + ++F++ +YG YC + + + + ++ +L C +A F L L++P QR LK ++ ++V H C+ ++ +T++ + QL L+ +GR + GEL + +++ YAFL D +L+C R Y + V + +++ S + H + L F R + W + A+ + P+ GH M +F+E TSC C ++ G F+QGYRC RC+A HK+C+G PC G S N GL K + + P L L+P +K + + + E+ P R W+AG + A L + GTFLVR+R
Sbjct: 1 MELWRQCTHWLIQCRVLPPSHRV--TWDGAQVCELAQALRDGVLLCQLLNNLLPHAINLREVNLRPQMSQ-------FLCLKNIRTFLSTCCEKFGLKRSE-LFEAFDLFDVQDFGKVIYTLSALSWTPIAQNKGIMPFPTEEESVG-----DEDIYSGLSDQIDDTVEEDEDLYDCVENE-EAEGDEIYEDLMRTEPMPMPPKMT---------EYDKRCCCLREIQQTEEKYTDTLGSIQQHFMKPLQRFLKPQDIEIIFINIEDLLRVHTHFLKEMKEALAAPTAPTLYQVFIKYKERFL-VYGRYCSQVESASKHLDRVATAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQDAVEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLAHYGRPKIDGELKITSVERRSKMDRYAFLLDKALLICKRRG---DSYDLKDFVNLHSFQVRDDSSGERENKKWTHMFLLIEDQGVQGYELFFKTRELKKK--WMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCHRCRAPAHKECLGRVPPCGRHGQDFSGTMKKDKPHRRAQDKKRNELGLPKMEVCQEYYGLPPPPGAFGPFLRLNPGDIVELTKAEAEQNWWEGRNTATNEVGWFPCNRVKPYVHGPPQDLSVHLWYAGPMERSGAESILTNRSDGTFLVRQR 698
BLAST of EMLSAG00000000123 vs. GO
Match: - (symbol:VAV1 "Proto-oncogene vav" species:9606 "Homo sapiens" [GO:0003700 "sequence-specific DNA binding transcription factor activity" evidence=TAS] [GO:0005085 "guanyl-nucleotide exchange factor activity" evidence=EXP;TAS] [GO:0005515 "protein binding" evidence=IPI] [GO:0005829 "cytosol" evidence=TAS] [GO:0005886 "plasma membrane" evidence=TAS] [GO:0006355 "regulation of transcription, DNA-templated" evidence=TAS] [GO:0007173 "epidermal growth factor receptor signaling pathway" evidence=TAS] [GO:0007229 "integrin-mediated signaling pathway" evidence=IEA] [GO:0007264 "small GTPase mediated signal transduction" evidence=TAS] [GO:0007596 "blood coagulation" evidence=TAS] [GO:0008543 "fibroblast growth factor receptor signaling pathway" evidence=TAS] [GO:0030168 "platelet activation" evidence=TAS] [GO:0030676 "Rac guanyl-nucleotide exchange factor activity" evidence=IEA] [GO:0031295 "T cell costimulation" evidence=TAS] [GO:0038095 "Fc-epsilon receptor signaling pathway" evidence=TAS] [GO:0038096 "Fc-gamma receptor signaling pathway involved in phagocytosis" evidence=TAS] [GO:0042110 "T cell activation" evidence=IEA] [GO:0043065 "positive regulation of apoptotic process" evidence=TAS] [GO:0045087 "innate immune response" evidence=TAS] [GO:0045785 "positive regulation of cell adhesion" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] [GO:0048011 "neurotrophin TRK receptor signaling pathway" evidence=TAS] [GO:0048015 "phosphatidylinositol-mediated signaling" evidence=TAS] [GO:0051056 "regulation of small GTPase mediated signal transduction" evidence=TAS] [GO:0097190 "apoptotic signaling pathway" evidence=TAS] Reactome:REACT_604 Reactome:REACT_85674 Pfam:PF00018 Pfam:PF00017 Pfam:PF00169 InterPro:IPR000219 InterPro:IPR000980 InterPro:IPR001331 InterPro:IPR001452 InterPro:IPR001715 InterPro:IPR002219 InterPro:IPR028530 Pfam:PF00130 Pfam:PF00307 Pfam:PF00621 PRINTS:PR00401 PRINTS:PR00452 PROSITE:PS00479 PROSITE:PS00741 PROSITE:PS50001 PROSITE:PS50002 PROSITE:PS50010 PROSITE:PS50021 PROSITE:PS50081 SMART:SM00033 SMART:SM00109 SMART:SM00252 SMART:SM00325 SMART:SM00326 InterPro:IPR001849 GO:GO:0005829 GO:GO:0005886 Reactome:REACT_111102 Reactome:REACT_116125 Reactome:REACT_6900 GO:GO:0007173 GO:GO:0038095 GO:GO:0008543 GO:GO:0045087 GO:GO:0048011 GO:GO:0007264 GO:GO:0030168 GO:GO:0031295 Gene3D:2.30.29.30 Gene3D:3.30.505.10 InterPro:IPR011993 SMART:SM00233 PROSITE:PS50003 GO:GO:0046872 GO:GO:0097190 GO:GO:0003700 GO:GO:0043065 GO:GO:0038096 SUPFAM:SSF50044 Gene3D:1.20.900.10 SUPFAM:SSF48065 GO:GO:0042110 GO:GO:0005085 Gene3D:1.10.418.10 SUPFAM:SSF47576 GO:GO:0007229 GO:GO:0045785 GO:GO:0048015 GO:GO:0032314 GO:GO:0030676 InterPro:IPR003096 PRINTS:PR00888 EMBL:AC020895 PDB:2LCT PDB:2MC1 PDBsum:2LCT PDBsum:2MC1 PDB:2ROR PDBsum:2ROR PDB:3BJI PDBsum:3BJI eggNOG:NOG326494 HOVERGEN:HBG018066 KO:K05730 OrthoDB:EOG73FQKZ TreeFam:TF316171 PANTHER:PTHR22826:SF53 HOGENOM:HOG000234364 CTD:7409 EMBL:AF030227 EMBL:AF030201 EMBL:AF030202 EMBL:AF030203 EMBL:AF030204 EMBL:AF030205 EMBL:AF030206 EMBL:AF030207 EMBL:AF030208 EMBL:AF030209 EMBL:AF030210 EMBL:AF030211 EMBL:AF030212 EMBL:AF030213 EMBL:AF030214 EMBL:AF030215 EMBL:AF030216 EMBL:AF030217 EMBL:AF030218 EMBL:AF030219 EMBL:AF030220 EMBL:AF030221 EMBL:AF030222 EMBL:AF030223 EMBL:AF030224 EMBL:AF030225 EMBL:AF030226 EMBL:AC010647 EMBL:AC020954 EMBL:AC022156 EMBL:M59834 EMBL:AK301128 EMBL:X16316 EMBL:X83931 PIR:B39576 RefSeq:NP_001245136.1 RefSeq:NP_005419.2 UniGene:Hs.116237 PDB:2CRH PDB:3KY9 PDBsum:2CRH PDBsum:3KY9 ProteinModelPortal:P15498 SMR:P15498 BioGrid:113252 DIP:DIP-1061N IntAct:P15498 MINT:MINT-1211643 STRING:9606.ENSP00000302269 PhosphoSite:P15498 DMDM:13124807 PaxDb:P15498 PeptideAtlas:P15498 PRIDE:P15498 DNASU:7409 Ensembl:ENST00000596764 Ensembl:ENST00000602142 GeneID:7409 KEGG:hsa:7409 UCSC:uc002mfu.2 GeneCards:GC19P006772 H-InvDB:HIX0202828 HGNC:HGNC:12657 HPA:HPA001864 MIM:164875 neXtProt:NX_P15498 PharmGKB:PA37280 InParanoid:P15498 OMA:SHRVTWD PhylomeDB:P15498 SignaLink:P15498 EvolutionaryTrace:P15498 GenomeRNAi:7409 NextBio:29008 PMAP-CutDB:P15498 PRO:PR:P15498 ArrayExpress:P15498 Bgee:P15498 CleanEx:HS_VAV1 Genevestigator:P15498 Uniprot:P15498) HSP 1 Score: 176.407 bits (446), Expect = 5.273e-45 Identity = 183/729 (25.10%), Postives = 310/729 (42.52%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDA--ETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHT----EILTGLNIKGS-QVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIH----------------------CLGKIDVVEKTIKLM---QLP---RGAQLSDFGRLRKAGELTAEN-SYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPLFHRIV-----PHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDY-PCLEVGST------------NSNASSINNNGLTKCDSVTLPTVINEPLERSESTLSLSPD-----SKQPSADRVSKLQRETEEELINIPVER--------------QSWFAGDLNPKTASVRLQSLPVGTFLVRKR 678
M LW++C WL +V+PP H++ T +++ + +RDGVLLCQL+++L P ++++ V SQ F+C NI FL F L E FE DL+ Q+ G VI TLSALS + + FP +E+ + +E+IYS + + D E E +YD + N+ + E IY+ + +++ S+ + KR + E+ TE+KY + L ++ F L L +D E+IF +++L+R+HT E+ L G+ + ++F++ +YG YC + + + + ++ +L C +A F L L++P QR LK ++ ++V H C+ ++ +T++ + QL L+ +GR + GEL + +++ YAFL D +L+C R Y + V + +++ S ++ H + L F R + W + A+ + P+ GH M +F+E TSC C ++ G F+QGYRC RC+A HK+C+G PC G + N GL K + + P L L+P +K + + + + E+ P R W+AG + A L + GTFLVR+R
Sbjct: 1 MELWRQCTHWLIQCRVLPPSHRV--TWDGAQVCELAQALRDGVLLCQLLNNLLPHAINLREVNLRPQMSQ-------FLCLKNIRTFLSTCCEKFGLKRSE-LFEAFDLFDVQDFGKVIYTLSALSWTPIAQNRGIMPFPTEEESVG-----DEDIYSGLSDQIDDTVEEDEDLYDC----VENEEAEGDE-IYEDLM--RSEPVSMP---PKMTEYDKRCCCLREIQQTEEKYTDTLGSIQQHFLKPLQRFLKPQDIEIIFINIEDLLRVHTHFLKEMKEALGTPGAANLYQVFIKYKERFL-VYGRYCSQVESASKHLDRVAAAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQEAMEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLAHYGRPKIDGELKITSVERRSKMDRYAFLLDKALLICKRRG---DSYDLKDFVNLHSFQVRDDSSGDRDNKKWSHMFLLIEDQGAQGYELFFKTRELKKK--WMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCHRCRASAHKECLGRVPPCGRHGQDFPGTMKKDKLHRRAQDKKRNELGLPKMEVFQEYYGLPPPPGAIGPFLRLNPGDIVELTKAEAEQNWWEGRNTSTNEIGWFPCNRVKPYVHGPPQDLSVHLWYAGPMERAGAESILANRSDGTFLVRQR 698
BLAST of EMLSAG00000000123 vs. GO
Match: - (symbol:Vav3 "vav 3 oncogene" species:10090 "Mus musculus" [GO:0001525 "angiogenesis" evidence=IEA] [GO:0005085 "guanyl-nucleotide exchange factor activity" evidence=ISO;IMP] [GO:0005089 "Rho guanyl-nucleotide exchange factor activity" evidence=IGI] [GO:0005154 "epidermal growth factor receptor binding" evidence=IPI] [GO:0005515 "protein binding" evidence=IPI] [GO:0005622 "intracellular" evidence=IMP] [GO:0005737 "cytoplasm" evidence=IDA] [GO:0005886 "plasma membrane" evidence=IDA] [GO:0006906 "vesicle fusion" evidence=IGI] [GO:0006974 "cellular response to DNA damage stimulus" evidence=ISO] [GO:0007229 "integrin-mediated signaling pathway" evidence=IGI] [GO:0007264 "small GTPase mediated signal transduction" evidence=IMP] [GO:0016477 "cell migration" evidence=IGI] [GO:0030031 "cell projection assembly" evidence=IGI] [GO:0030032 "lamellipodium assembly" evidence=IGI] [GO:0030593 "neutrophil chemotaxis" evidence=IGI] [GO:0030676 "Rac guanyl-nucleotide exchange factor activity" evidence=IGI] [GO:0030890 "positive regulation of B cell proliferation" evidence=ISO] [GO:0032314 "regulation of Rac GTPase activity" evidence=IGI] [GO:0035023 "regulation of Rho protein signal transduction" evidence=IEA] [GO:0035556 "intracellular signal transduction" evidence=IEA] [GO:0042493 "response to drug" evidence=ISO] [GO:0043087 "regulation of GTPase activity" evidence=IGI;IMP] [GO:0043552 "positive regulation of phosphatidylinositol 3-kinase activity" evidence=IGI] [GO:0045785 "positive regulation of cell adhesion" evidence=IGI] [GO:0046872 "metal ion binding" evidence=IEA] [GO:0050853 "B cell receptor signaling pathway" evidence=ISO] Pfam:PF00017 Pfam:PF00169 InterPro:IPR000219 InterPro:IPR000980 InterPro:IPR001331 InterPro:IPR001452 InterPro:IPR001715 InterPro:IPR002219 InterPro:IPR028530 Pfam:PF00130 Pfam:PF00621 PRINTS:PR00401 PRINTS:PR00452 PROSITE:PS00479 PROSITE:PS00741 PROSITE:PS50001 PROSITE:PS50002 PROSITE:PS50010 PROSITE:PS50021 PROSITE:PS50081 SMART:SM00033 SMART:SM00109 SMART:SM00252 SMART:SM00325 SMART:SM00326 InterPro:IPR001849 MGI:MGI:1888518 GO:GO:0005886 GO:GO:0005737 GO:GO:0007264 GO:GO:0042493 Gene3D:2.30.29.30 Gene3D:3.30.505.10 InterPro:IPR011993 SMART:SM00233 PROSITE:PS50003 GO:GO:0046872 GO:GO:0001525 GO:GO:0006974 SUPFAM:SSF50044 GO:GO:0016477 Gene3D:1.20.900.10 SUPFAM:SSF48065 GO:GO:0030890 Gene3D:1.10.418.10 SUPFAM:SSF47576 GO:GO:0007229 GO:GO:0045785 GO:GO:0030032 GO:GO:0030676 InterPro:IPR011511 Pfam:PF07653 InterPro:IPR003096 PRINTS:PR00888 InterPro:IPR022613 Pfam:PF11971 GO:GO:0050853 GO:GO:0006906 GO:GO:0043552 eggNOG:NOG326494 HOVERGEN:HBG018066 KO:K05730 OrthoDB:EOG73FQKZ TreeFam:TF316171 PANTHER:PTHR22826:SF53 GeneTree:ENSGT00740000115307 HOGENOM:HOG000234364 CTD:10451 OMA:DPGLPKM ChiTaRS:VAV3 EMBL:AF067816 EMBL:AF140280 EMBL:AK033253 EMBL:AK041249 EMBL:AK147053 EMBL:AL731716 EMBL:AL671857 EMBL:AL671987 EMBL:CR936838 EMBL:CR936848 EMBL:CR936849 EMBL:CR938729 EMBL:BC027242 EMBL:BC052739 RefSeq:NP_065251.2 RefSeq:NP_666251.1 UniGene:Mm.282257 ProteinModelPortal:Q9R0C8 SMR:Q9R0C8 STRING:10090.ENSMUSP00000036270 PhosphoSite:Q9R0C8 PaxDb:Q9R0C8 PRIDE:Q9R0C8 Ensembl:ENSMUST00000046864 Ensembl:ENSMUST00000106576 GeneID:57257 KEGG:mmu:57257 UCSC:uc008raf.1 UCSC:uc008rag.1 UCSC:uc008rah.1 InParanoid:Q9R0C8 NextBio:313559 PRO:PR:Q9R0C8 ArrayExpress:Q9R0C8 Bgee:Q9R0C8 CleanEx:MM_VAV3 Genevestigator:Q9R0C8 Uniprot:Q9R0C8) HSP 1 Score: 175.637 bits (444), Expect = 7.282e-45 Identity = 144/591 (24.37%), Postives = 256/591 (43.32%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDA---ETEYIYDSFAKDIYNDTQDNYENIYQTICA--PKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGL-----NIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHCLGKIDVVEKTIKLMQLPRGAQLSD----------------------------FGRLRKAGELTAEN-SYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPL---FHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIG 571
M WK+C WL + KV+PP H++ T ++++ D +RDGVLLCQL+++L P S+++ + SQ F+C NI FL A F + E FE DL+ ++ G VIETLS LS + + FP +E N+E+IY + ++ + + E +YD + ++ + YE++ + A PK+Q + R + E+ TE+KY E L + F L L++ + + +F + +L+++H ++ + N + ++F+ + +YG YC + ++ + + K ++ +L C +A F L L++P QR LK ++ ++V H ++ + L + AQ + FGR + GE+ + + FLFD +++C R Y + + ++ Y+I + + F+ I L F C+ ++ W + A+ + P H M TF TSC C ++ G F+QGY C +C A HK+C+G
Sbjct: 1 MEPWKQCAQWLIHSKVLPPNHRV--TWDSAQVFDLAQTLRDGVLLCQLLNNLRPHSINLKEINLRPQMSQ-------FLCLKNIRTFLAACCDTFGMRKSE-LFEAFDLFDVRDFGKVIETLSRLSRTPIALATGIRPFPTEES------INDEDIYKGLPDLIDETRVEDEEDLYDCVYGE--DEGGEVYEDLMKAEEAQQPKSQENDI------------RSCCLAEIRQTEEKYTETLESIEKYFMAPLKRFLTAAEFDSVFINIPDLVKVHRSLMQEIHDSIVNKDDQNLYQVFINYKERLV-IYGQYCSGVESAISNLDYISKTKEDVKLKLEECSKRANNGKFTLRDLLVVPMQRVLKYHLLLQELVKHTHDPMEKANLKLALDAMKDLAQYVNEVKRDNETLREIKQFQLSIENLNQPVLLFGRPQGDGEIRITTLDKHTKQERHIFLFDLAVIVCKRKG---DNYEMKEIIDLQQYKIANNPTTDKENKKWSYGFYLIHTQGQNGLEFYCKTKDLKKKWLEQFEMALSNIRPDYADSNFHDFKMHTFTRVTSCRVCQMLLRGTFYQGYLCFKCGAKAHKECLG 557
BLAST of EMLSAG00000000123 vs. GO
Match: - (symbol:Vav1 "Proto-oncogene vav" species:10116 "Rattus norvegicus" [GO:0006909 "phagocytosis" evidence=IEA] [GO:0006955 "immune response" evidence=IEA] [GO:0007229 "integrin-mediated signaling pathway" evidence=IEA] [GO:0030676 "Rac guanyl-nucleotide exchange factor activity" evidence=IEA] [GO:0042110 "T cell activation" evidence=IEA] [GO:0045785 "positive regulation of cell adhesion" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] Pfam:PF00018 Pfam:PF00017 InterPro:IPR000219 InterPro:IPR000980 InterPro:IPR001331 InterPro:IPR001452 InterPro:IPR001715 InterPro:IPR002219 InterPro:IPR028530 Pfam:PF00130 Pfam:PF00621 PRINTS:PR00401 PRINTS:PR00452 PROSITE:PS00479 PROSITE:PS00741 PROSITE:PS50001 PROSITE:PS50002 PROSITE:PS50010 PROSITE:PS50021 PROSITE:PS50081 SMART:SM00033 SMART:SM00109 SMART:SM00252 SMART:SM00325 SMART:SM00326 RGD:3951 GO:GO:0007264 GO:GO:0006955 GO:GO:0006909 Gene3D:2.30.29.30 Gene3D:3.30.505.10 InterPro:IPR011993 GO:GO:0046872 SUPFAM:SSF50044 Gene3D:1.20.900.10 SUPFAM:SSF48065 GO:GO:0042110 Gene3D:1.10.418.10 SUPFAM:SSF47576 GO:GO:0007229 GO:GO:0045785 GO:GO:0032314 GO:GO:0030676 InterPro:IPR011511 Pfam:PF07653 InterPro:IPR003096 PRINTS:PR00888 InterPro:IPR022613 Pfam:PF11971 OrthoDB:EOG73FQKZ PANTHER:PTHR22826:SF53 GeneTree:ENSGT00740000115307 OMA:SHRVTWD EMBL:AABR06058360 EMBL:AABR06058354 EMBL:AABR06058355 EMBL:AABR06058356 EMBL:AABR06058357 EMBL:AABR06058358 EMBL:AABR06058359 Ensembl:ENSRNOT00000073294 Uniprot:M0R4H8) HSP 1 Score: 173.326 bits (438), Expect = 4.729e-44 Identity = 155/593 (26.14%), Postives = 265/593 (44.69%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDA--ETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGLNIKGSQVG-----EIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIH----------------------CLGKIDVVEKTIKLM---QLP---RGAQLSDFGRLRKAGELTAENSYGARLSD-YAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNS--IPLFHR---IVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYP 574
M LW++C WL +V+PP H++ T +++ + +RDGVLLCQL+++L P ++++ V SQ F+C NI FL F L E FE DL+ Q+ G VI TLSALS + + FP ++ L +E+IYS + + D E E +YD + + + YE++ ++ P + + KR + E+ TE+KY + L ++ F L L +D E IF ++EL+ +HT L L S G ++F++ +YG YC + + + + ++ +L C +A F L L++P QR LK ++ ++V H C+ ++ +T++ + QL L+++GR + GEL + +D YAFL D +L+C R Y + +V + +++ S ++ + L H+ + + L + +W + + + P+ GH M +F+E TSC C ++ G F+QGYRC RC+A HK+C+G P
Sbjct: 1 MELWRQCTHWLIQCRVLPPSHRV--TWEGAQVCELAQALRDGVLLCQLLNNLLPHAINLREVNLWPQMSQ-------FLCLKNIRTFLSTCCEKFGLKRSE-LFEAFDLFDVQDFGKVIYTLSALSWTPIAQNKGIMPFPTEDSALG-----DEDIYSGLSDQIDDTAEEDEDLYDCVENE-EAEGDEIYEDLMRSESVPTPPKMT---------EYDKRCCCLREIQQTEEKYTDTLGSIQQHFMKPLQRFLKPQDMETIFVNIEELLSVHTHFLKELKDALSGPGATMLYQVFIKYKERFL-VYGRYCSQVESASKHLDQVATAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQDTTEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLANYGRPKIDGELKITSVERRSKTDRYAFLLDKALLICKRRG---DSYDLKASVNLHSFQVRDDSSGERDNKKVGLCHQDSAVQELGSLALGLPWSWVQLKHLWMDVHSLSSSNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCYRCRAPAHKECLGRVP 564
BLAST of EMLSAG00000000123 vs. GO
Match: - (symbol:Vav3 "Protein Vav3" species:10116 "Rattus norvegicus" [GO:0005154 "epidermal growth factor receptor binding" evidence=IEA] [GO:0005737 "cytoplasm" evidence=IEA] [GO:0005886 "plasma membrane" evidence=IEA] [GO:0006906 "vesicle fusion" evidence=IEA] [GO:0006974 "cellular response to DNA damage stimulus" evidence=IEA] [GO:0007229 "integrin-mediated signaling pathway" evidence=IEA] [GO:0007264 "small GTPase mediated signal transduction" evidence=IEA] [GO:0016477 "cell migration" evidence=IEA] [GO:0030032 "lamellipodium assembly" evidence=IEA] [GO:0030676 "Rac guanyl-nucleotide exchange factor activity" evidence=IEA] [GO:0030890 "positive regulation of B cell proliferation" evidence=IEA] [GO:0042493 "response to drug" evidence=IEA] [GO:0043552 "positive regulation of phosphatidylinositol 3-kinase activity" evidence=IEA] [GO:0045785 "positive regulation of cell adhesion" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] [GO:0050853 "B cell receptor signaling pathway" evidence=IEA] Pfam:PF00017 Pfam:PF00169 InterPro:IPR000219 InterPro:IPR000980 InterPro:IPR001331 InterPro:IPR001452 InterPro:IPR001715 InterPro:IPR002219 InterPro:IPR028530 Pfam:PF00130 Pfam:PF00621 PRINTS:PR00401 PRINTS:PR00452 PROSITE:PS00479 PROSITE:PS00741 PROSITE:PS50001 PROSITE:PS50002 PROSITE:PS50010 PROSITE:PS50021 PROSITE:PS50081 SMART:SM00033 SMART:SM00109 SMART:SM00252 SMART:SM00325 SMART:SM00326 InterPro:IPR001849 RGD:1565941 GO:GO:0005886 GO:GO:0005737 GO:GO:0007264 GO:GO:0042493 Gene3D:2.30.29.30 Gene3D:3.30.505.10 InterPro:IPR011993 SMART:SM00233 PROSITE:PS50003 GO:GO:0046872 GO:GO:0006974 SUPFAM:SSF50044 GO:GO:0016477 Gene3D:1.20.900.10 SUPFAM:SSF48065 GO:GO:0030890 Gene3D:1.10.418.10 SUPFAM:SSF47576 GO:GO:0007229 GO:GO:0045785 GO:GO:0032314 GO:GO:0030032 GO:GO:0030676 InterPro:IPR011511 Pfam:PF07653 InterPro:IPR003096 PRINTS:PR00888 InterPro:IPR022613 Pfam:PF11971 GO:GO:0050853 GO:GO:0006906 GO:GO:0043552 KO:K05730 OrthoDB:EOG73FQKZ TreeFam:TF316171 PANTHER:PTHR22826:SF53 GeneTree:ENSGT00740000115307 CTD:10451 OMA:DPGLPKM EMBL:AABR06019932 EMBL:AABR06019930 EMBL:AABR06019931 EMBL:AABR06019933 RefSeq:NP_001178643.1 UniGene:Rn.27881 PRIDE:F1LWB1 Ensembl:ENSRNOT00000027813 GeneID:295378 KEGG:rno:295378 UCSC:RGD:1565941 NextBio:35578393 Uniprot:F1LWB1) HSP 1 Score: 172.94 bits (437), Expect = 7.424e-44 Identity = 141/588 (23.98%), Postives = 251/588 (42.69%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDT--QDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGL-----NIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHCLGKIDVVEKTIKLMQLPRGAQLSD----------------------------FGRLRKAGELTAEN-SYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPL---FHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIG 571
M WK+C WL + KV+P H++ T ++++ D +RDGVLLCQL+++L P S+++ + SQ F+C NI FL A F + E FE DL+ ++ G VIETLS LS + + FP +E N+E+IY + ++ + E +D+Y+ +D +Y+ + + E + + R + E+ TE+KY E L + F L L++ + + +F + +L+++H ++ + N + ++F+ + +YG YC + ++ + + K +R +L C +A F L L++P QR LK ++ ++V H ++ + L + AQ + FGR + GE+ + + FLFD +++C R Y + + ++ Y+I + + F+ I L F C+ ++ W + A+ + P H M TF TSC C ++ G F+QGY C +C A HK+C+G
Sbjct: 1 MEPWKQCAQWLIHCKVLPANHRV--TWDSAQVFDLAQTLRDGVLLCQLLNNLRPHSINLKEINLRPQMSQ-------FLCLKNIRTFLAACCDTFGMKKSE-LFEAFDLFDVRDFGKVIETLSRLSRTPIALATGIRPFPTEES------VNDEDIYKGLPDLIDETRVED-----EEDLYDCVYGEDEGGEVYEDLMKAE------EAHQAKSQENDIRSCCLAEIRQTEEKYTETLESIEKYFMAPLKRFLTAAEFDSVFINIPDLVKVHRSLMQEIHDSIVNKDDHNLYQVFINYKERLV-IYGQYCSGVESAISSLDYISKTKEDVRLKLEECSKRANNGKFTLRDLLVVPMQRVLKYHLLLQELVKHTHDPMEKSNLKLALDAMKDLAQYVNEVKRDNETLREIKQFQLSIENLNQPVLLFGRPQGDGEIRITTLDKHTKQERHIFLFDLAVIVCKRKG---DNYEMKEIIDLQQYKIANNPTTDKENKKWSYGFYLIHTQGQNGLEFYCKTKDLKKKWLEQFEMALSNIRPDYADSNFHDFKMHTFTRVTSCRVCQMLLRGTFYQGYLCFKCGAKAHKECLG 557
BLAST of EMLSAG00000000123 vs. GO
Match: - (symbol:Vav3 "vav 3 guanine nucleotide exchange factor" species:10116 "Rattus norvegicus" [GO:0005085 "guanyl-nucleotide exchange factor activity" evidence=ISO] [GO:0005089 "Rho guanyl-nucleotide exchange factor activity" evidence=ISO] [GO:0005154 "epidermal growth factor receptor binding" evidence=IEA;ISO] [GO:0005622 "intracellular" evidence=ISO] [GO:0005737 "cytoplasm" evidence=IEA;ISO] [GO:0005886 "plasma membrane" evidence=IEA;ISO] [GO:0006906 "vesicle fusion" evidence=IEA;ISO] [GO:0006974 "cellular response to DNA damage stimulus" evidence=IEA;ISO] [GO:0007229 "integrin-mediated signaling pathway" evidence=IEA;ISO] [GO:0007264 "small GTPase mediated signal transduction" evidence=IEA;ISO] [GO:0016477 "cell migration" evidence=IEA;ISO] [GO:0030031 "cell projection assembly" evidence=ISO] [GO:0030032 "lamellipodium assembly" evidence=IEA;ISO] [GO:0030593 "neutrophil chemotaxis" evidence=ISO] [GO:0030676 "Rac guanyl-nucleotide exchange factor activity" evidence=IEA;ISO] [GO:0030890 "positive regulation of B cell proliferation" evidence=IEA;ISO] [GO:0032314 "regulation of Rac GTPase activity" evidence=ISO] [GO:0042493 "response to drug" evidence=IEA;ISO] [GO:0043087 "regulation of GTPase activity" evidence=ISO] [GO:0043552 "positive regulation of phosphatidylinositol 3-kinase activity" evidence=IEA;ISO] [GO:0045785 "positive regulation of cell adhesion" evidence=IEA;ISO] [GO:0046872 "metal ion binding" evidence=IEA] [GO:0050853 "B cell receptor signaling pathway" evidence=IEA;ISO] Pfam:PF00017 Pfam:PF00169 InterPro:IPR000219 InterPro:IPR000980 InterPro:IPR001331 InterPro:IPR001452 InterPro:IPR001715 InterPro:IPR002219 InterPro:IPR028530 Pfam:PF00130 Pfam:PF00621 PRINTS:PR00401 PRINTS:PR00452 PROSITE:PS00479 PROSITE:PS00741 PROSITE:PS50001 PROSITE:PS50002 PROSITE:PS50010 PROSITE:PS50021 PROSITE:PS50081 SMART:SM00033 SMART:SM00109 SMART:SM00252 SMART:SM00325 SMART:SM00326 InterPro:IPR001849 RGD:1565941 GO:GO:0005886 GO:GO:0005737 GO:GO:0007264 GO:GO:0042493 Gene3D:2.30.29.30 Gene3D:3.30.505.10 InterPro:IPR011993 SMART:SM00233 PROSITE:PS50003 GO:GO:0046872 GO:GO:0006974 SUPFAM:SSF50044 GO:GO:0016477 Gene3D:1.20.900.10 SUPFAM:SSF48065 GO:GO:0030890 Gene3D:1.10.418.10 SUPFAM:SSF47576 GO:GO:0007229 GO:GO:0045785 GO:GO:0032314 GO:GO:0030032 GO:GO:0030676 InterPro:IPR011511 Pfam:PF07653 InterPro:IPR003096 PRINTS:PR00888 InterPro:IPR022613 Pfam:PF11971 GO:GO:0050853 GO:GO:0006906 GO:GO:0043552 KO:K05730 OrthoDB:EOG73FQKZ TreeFam:TF316171 PANTHER:PTHR22826:SF53 GeneTree:ENSGT00740000115307 CTD:10451 OMA:DPGLPKM EMBL:AABR06019932 EMBL:AABR06019930 EMBL:AABR06019931 EMBL:AABR06019933 RefSeq:NP_001178643.1 UniGene:Rn.27881 PRIDE:F1LWB1 Ensembl:ENSRNOT00000027813 GeneID:295378 KEGG:rno:295378 UCSC:RGD:1565941 NextBio:35578393 Uniprot:F1LWB1) HSP 1 Score: 172.94 bits (437), Expect = 7.424e-44 Identity = 141/588 (23.98%), Postives = 251/588 (42.69%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDT--QDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGL-----NIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHCLGKIDVVEKTIKLMQLPRGAQLSD----------------------------FGRLRKAGELTAEN-SYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPL---FHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIG 571
M WK+C WL + KV+P H++ T ++++ D +RDGVLLCQL+++L P S+++ + SQ F+C NI FL A F + E FE DL+ ++ G VIETLS LS + + FP +E N+E+IY + ++ + E +D+Y+ +D +Y+ + + E + + R + E+ TE+KY E L + F L L++ + + +F + +L+++H ++ + N + ++F+ + +YG YC + ++ + + K +R +L C +A F L L++P QR LK ++ ++V H ++ + L + AQ + FGR + GE+ + + FLFD +++C R Y + + ++ Y+I + + F+ I L F C+ ++ W + A+ + P H M TF TSC C ++ G F+QGY C +C A HK+C+G
Sbjct: 1 MEPWKQCAQWLIHCKVLPANHRV--TWDSAQVFDLAQTLRDGVLLCQLLNNLRPHSINLKEINLRPQMSQ-------FLCLKNIRTFLAACCDTFGMKKSE-LFEAFDLFDVRDFGKVIETLSRLSRTPIALATGIRPFPTEES------VNDEDIYKGLPDLIDETRVED-----EEDLYDCVYGEDEGGEVYEDLMKAE------EAHQAKSQENDIRSCCLAEIRQTEEKYTETLESIEKYFMAPLKRFLTAAEFDSVFINIPDLVKVHRSLMQEIHDSIVNKDDHNLYQVFINYKERLV-IYGQYCSGVESAISSLDYISKTKEDVRLKLEECSKRANNGKFTLRDLLVVPMQRVLKYHLLLQELVKHTHDPMEKSNLKLALDAMKDLAQYVNEVKRDNETLREIKQFQLSIENLNQPVLLFGRPQGDGEIRITTLDKHTKQERHIFLFDLAVIVCKRKG---DNYEMKEIIDLQQYKIANNPTTDKENKKWSYGFYLIHTQGQNGLEFYCKTKDLKKKWLEQFEMALSNIRPDYADSNFHDFKMHTFTRVTSCRVCQMLLRGTFYQGYLCFKCGAKAHKECLG 557
BLAST of EMLSAG00000000123 vs. GO
Match: - (symbol:VAV3 "Uncharacterized protein" species:9913 "Bos taurus" [GO:0005154 "epidermal growth factor receptor binding" evidence=IEA] [GO:0005737 "cytoplasm" evidence=IEA] [GO:0005886 "plasma membrane" evidence=IEA] [GO:0006906 "vesicle fusion" evidence=IEA] [GO:0006974 "cellular response to DNA damage stimulus" evidence=IEA] [GO:0007229 "integrin-mediated signaling pathway" evidence=IEA] [GO:0007264 "small GTPase mediated signal transduction" evidence=IEA] [GO:0016477 "cell migration" evidence=IEA] [GO:0030032 "lamellipodium assembly" evidence=IEA] [GO:0030676 "Rac guanyl-nucleotide exchange factor activity" evidence=IEA] [GO:0030890 "positive regulation of B cell proliferation" evidence=IEA] [GO:0042493 "response to drug" evidence=IEA] [GO:0043552 "positive regulation of phosphatidylinositol 3-kinase activity" evidence=IEA] [GO:0045785 "positive regulation of cell adhesion" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] [GO:0050853 "B cell receptor signaling pathway" evidence=IEA] Pfam:PF00017 Pfam:PF00169 InterPro:IPR000219 InterPro:IPR000980 InterPro:IPR001331 InterPro:IPR001452 InterPro:IPR001715 InterPro:IPR002219 InterPro:IPR028530 Pfam:PF00130 Pfam:PF00621 PRINTS:PR00401 PRINTS:PR00452 PROSITE:PS00479 PROSITE:PS00741 PROSITE:PS50001 PROSITE:PS50002 PROSITE:PS50010 PROSITE:PS50021 PROSITE:PS50081 SMART:SM00033 SMART:SM00109 SMART:SM00252 SMART:SM00325 SMART:SM00326 InterPro:IPR001849 GO:GO:0005886 GO:GO:0005737 GO:GO:0007264 GO:GO:0042493 Gene3D:2.30.29.30 Gene3D:3.30.505.10 InterPro:IPR011993 SMART:SM00233 PROSITE:PS50003 GO:GO:0046872 GO:GO:0006974 SUPFAM:SSF50044 GO:GO:0016477 Gene3D:1.20.900.10 SUPFAM:SSF48065 GO:GO:0030890 Gene3D:1.10.418.10 SUPFAM:SSF47576 GO:GO:0007229 GO:GO:0045785 GO:GO:0032314 GO:GO:0030032 GO:GO:0030676 InterPro:IPR011511 Pfam:PF07653 InterPro:IPR022613 Pfam:PF11971 GO:GO:0050853 GO:GO:0006906 GO:GO:0043552 KO:K05730 OrthoDB:EOG73FQKZ TreeFam:TF316171 PANTHER:PTHR22826:SF53 GeneTree:ENSGT00740000115307 CTD:10451 OMA:DPGLPKM EMBL:DAAA02007603 EMBL:DAAA02007604 EMBL:DAAA02007605 EMBL:DAAA02007606 EMBL:DAAA02007607 EMBL:DAAA02007608 EMBL:DAAA02007609 EMBL:DAAA02007610 EMBL:DAAA02007611 RefSeq:XP_002686208.1 UniGene:Bt.110722 ProteinModelPortal:E1BBD2 Ensembl:ENSBTAT00000020771 GeneID:521961 KEGG:bta:521961 NextBio:20873410 ArrayExpress:E1BBD2 Uniprot:E1BBD2) HSP 1 Score: 172.94 bits (437), Expect = 7.634e-44 Identity = 171/728 (23.49%), Postives = 288/728 (39.56%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGL-----NIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHCLGKIDVVEKTIKLMQLPRGAQLSD----------------------------FGRLRKAGELTAEN-SYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPL---FHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYP-CLEVGSTNSNA---SSINNNGLTKCDSVTLPTVINEPLERSES-----TLSLSPDSKQPSADRVSKLQRE-----------TEEELINIPVER---------------QSWFAGDLNPKTASVRLQSLPVGTFLVRKR 678
M WK+C WL + KV+P H++ T ++++ D +RDGV+LCQL+++L S+++ + SQ F+C NI FL A F + E FE DL+ ++ G VIETLS LS + + FP +E N+++IY + ++ + E D +Y +D +Y+ + + E S R + E+ TE+KY E L + F L L++ + + +F + EL+++H ++ + N + ++F+ + +YG YC + ++ + + K +R +L C +A F L L++P QR LK ++ ++V H ++ + L + AQ + FGR + GE+ + + FLFD +++C R Y + + ++ Y+I + + F+ I L F C+ ++ W + A+ + P H M TF TSC C ++ G FFQGY C +C A HK+C+G C V S S NGL + P + RS S L P + D V L+ + T E+ P + Q W+AG + A L + T+LVR R
Sbjct: 1 MEPWKQCAQWLIHCKVLPANHRV--TWDSAQVFDLAQTLRDGVMLCQLLNNLRAHSINLKEINLRPQMSQ-------FLCLKNIRTFLTACCETFGMRKSE-LFEAFDLFDVRDFGKVIETLSRLSRTPIALATGIRPFPTEES------INDDDIYKGLPDLIDETHVE-DEDGLYDCVYG--EDEGGEVYEDLMKAE------EAQQSKCPENDIRSCCLAEIKQTEEKYTETLESIEKYFMAPLKRFLTAAEFDSVFINIPELVKVHRNLMQEIHDSIVNKNDQNLYQVFINYKERLV-IYGQYCSGVESAISSLDYISKTKEDVRLKLEECSKRANNGKFTLRDLLVVPMQRVLKYHLLLQELVKHTTDPMEKANLKLALDAMKDLAQYVNEVKRDNETLREIKQFQLSIENLNQPVLLFGRPQGDGEIRITTLDKHTKQERHIFLFDLAVIVCKRKG---DNYEMKEIIDLQQYKIANNPTTDKENKKWSYGFYLIHIQGQNGLEFYCKTKDLKKKWLEQFEMALSNIRPDYADSNFHEFKMHTFTRVTSCRVCQMLLRGTFFQGYLCVKCGARAHKECLGRVDNCSRVNSAEQGTLKPSEKRTNGLRRTHRPVDPGLPKMQAIRSYSGTPPPALHEGPPLHIQAGDTVELLRGDAHSLFWQGRNLTSGEVGFFPSDAVKPCPCVPKPVDYSCQPWYAGAMERLQAETELINRVNSTYLVRHR 699
BLAST of EMLSAG00000000123 vs. GO
Match: - (symbol:VAV3 "Guanine nucleotide exchange factor VAV3" species:9606 "Homo sapiens" [GO:0001525 "angiogenesis" evidence=IEA] [GO:0005070 "SH3/SH2 adaptor activity" evidence=TAS] [GO:0005085 "guanyl-nucleotide exchange factor activity" evidence=EXP;TAS] [GO:0005096 "GTPase activator activity" evidence=TAS] [GO:0005154 "epidermal growth factor receptor binding" evidence=IEA] [GO:0005515 "protein binding" evidence=IPI] [GO:0005829 "cytosol" evidence=TAS] [GO:0005886 "plasma membrane" evidence=IEA] [GO:0006906 "vesicle fusion" evidence=IEA] [GO:0006974 "cellular response to DNA damage stimulus" evidence=IMP] [GO:0007229 "integrin-mediated signaling pathway" evidence=IEA] [GO:0007264 "small GTPase mediated signal transduction" evidence=TAS] [GO:0007596 "blood coagulation" evidence=TAS] [GO:0009967 "positive regulation of signal transduction" evidence=TAS] [GO:0016477 "cell migration" evidence=IEA] [GO:0030032 "lamellipodium assembly" evidence=IEA] [GO:0030168 "platelet activation" evidence=TAS] [GO:0030676 "Rac guanyl-nucleotide exchange factor activity" evidence=IEA] [GO:0030890 "positive regulation of B cell proliferation" evidence=IMP] [GO:0038095 "Fc-epsilon receptor signaling pathway" evidence=TAS] [GO:0038096 "Fc-gamma receptor signaling pathway involved in phagocytosis" evidence=TAS] [GO:0042493 "response to drug" evidence=IMP] [GO:0043065 "positive regulation of apoptotic process" evidence=TAS] [GO:0043547 "positive regulation of GTPase activity" evidence=TAS] [GO:0043552 "positive regulation of phosphatidylinositol 3-kinase activity" evidence=IEA] [GO:0045087 "innate immune response" evidence=TAS] [GO:0045785 "positive regulation of cell adhesion" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] [GO:0048011 "neurotrophin TRK receptor signaling pathway" evidence=TAS] [GO:0050853 "B cell receptor signaling pathway" evidence=IMP] [GO:0051056 "regulation of small GTPase mediated signal transduction" evidence=TAS] [GO:0097190 "apoptotic signaling pathway" evidence=TAS] Reactome:REACT_604 Pfam:PF00017 Pfam:PF00169 InterPro:IPR000219 InterPro:IPR000980 InterPro:IPR001331 InterPro:IPR001452 InterPro:IPR001715 InterPro:IPR002219 InterPro:IPR028530 Pfam:PF00130 Pfam:PF00307 Pfam:PF00621 PRINTS:PR00401 PRINTS:PR00452 PROSITE:PS00479 PROSITE:PS00741 PROSITE:PS50001 PROSITE:PS50002 PROSITE:PS50010 PROSITE:PS50021 PROSITE:PS50081 SMART:SM00033 SMART:SM00109 SMART:SM00252 SMART:SM00325 SMART:SM00326 InterPro:IPR001849 GO:GO:0005829 GO:GO:0005886 Reactome:REACT_111102 Reactome:REACT_6900 GO:GO:0038095 GO:GO:0045087 GO:GO:0048011 GO:GO:0007264 GO:GO:0030168 GO:GO:0042493 GO:GO:0005096 GO:GO:0005070 Gene3D:2.30.29.30 Gene3D:3.30.505.10 InterPro:IPR011993 SMART:SM00233 PROSITE:PS50003 GO:GO:0046872 GO:GO:0097190 GO:GO:0001525 GO:GO:0006974 GO:GO:0043065 GO:GO:0038096 SUPFAM:SSF50044 GO:GO:0016477 Gene3D:1.20.900.10 SUPFAM:SSF48065 GO:GO:0030890 GO:GO:0005085 Gene3D:1.10.418.10 SUPFAM:SSF47576 GO:GO:0007229 GO:GO:0045785 GO:GO:0032314 GO:GO:0030032 GO:GO:0030676 EMBL:CH471156 InterPro:IPR011511 Pfam:PF07653 InterPro:IPR003096 PRINTS:PR00888 GO:GO:0050853 GO:GO:0006906 GO:GO:0043552 EMBL:AC114491 eggNOG:NOG326494 HOVERGEN:HBG018066 KO:K05730 OrthoDB:EOG73FQKZ TreeFam:TF316171 PANTHER:PTHR22826:SF53 EMBL:AF035442 EMBL:AF067817 EMBL:AF118887 EMBL:AF118886 EMBL:AK304088 EMBL:AK316295 EMBL:AL391235 EMBL:AL353892 EMBL:AL513206 EMBL:AL591042 EMBL:BC143969 RefSeq:NP_001073343.1 RefSeq:NP_006104.4 RefSeq:XP_005270415.1 RefSeq:XP_005270417.1 UniGene:Hs.267659 PDB:2D86 PDBsum:2D86 ProteinModelPortal:Q9UKW4 SMR:Q9UKW4 BioGrid:115715 IntAct:Q9UKW4 MINT:MINT-256977 STRING:9606.ENSP00000359073 PhosphoSite:Q9UKW4 DMDM:12643372 PaxDb:Q9UKW4 PRIDE:Q9UKW4 DNASU:10451 Ensembl:ENST00000370056 Ensembl:ENST00000415432 Ensembl:ENST00000527011 GeneID:10451 KEGG:hsa:10451 UCSC:uc001dvj.1 UCSC:uc001dvk.1 UCSC:uc010ouw.1 CTD:10451 GeneCards:GC01M108113 HGNC:HGNC:12659 HPA:CAB002012 HPA:HPA028138 MIM:605541 neXtProt:NX_Q9UKW4 PharmGKB:PA37282 HOGENOM:HOG000049191 InParanoid:Q9UKW4 OMA:DPGLPKM PhylomeDB:Q9UKW4 SignaLink:Q9UKW4 ChiTaRS:VAV3 EvolutionaryTrace:Q9UKW4 GeneWiki:VAV3 GenomeRNAi:10451 NextBio:39617 PRO:PR:Q9UKW4 ArrayExpress:Q9UKW4 Bgee:Q9UKW4 CleanEx:HS_VAV3 Genevestigator:Q9UKW4 Uniprot:Q9UKW4) HSP 1 Score: 169.859 bits (429), Expect = 7.859e-43 Identity = 142/589 (24.11%), Postives = 248/589 (42.11%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDA---ETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGL-----NIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHCLGKIDVVEKTIKLMQLPRGAQLSD----------------------------FGRLRKAGELTAEN-SYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPL---FHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIG 571
M WK+C WL + KV+P H++ T ++++ D +RDGVLLCQL+++L S+++ + SQ F+C NI FL A F + E FE DL+ ++ G VIETLS LS + + FP +E N+E+IY + ++ + + E +YD +Y +D +Y+ + + E R + E+ TE+KY E L + F L L++ + + +F + EL++LH ++ + N + ++F+ + +YG YC + ++ + + K ++ +L C +A F L L++P QR LK ++ ++V H + + L + AQ + FGR + GE+ + + FLFD +++C R Y + + ++ Y+I + + F+ I L F C+ ++ W + A+ + P H M TF TSC C ++ G F+QGY C +C A HK+C+G
Sbjct: 1 MEPWKQCAQWLIHCKVLPTNHRV--TWDSAQVFDLAQTLRDGVLLCQLLNNLRAHSINLKEINLRPQMSQ-------FLCLKNIRTFLTACCETFGMRKSE-LFEAFDLFDVRDFGKVIETLSRLSRTPIALATGIRPFPTEES------INDEDIYKGLPDLIDETLVEDEEDLYDC----VYG--EDEGGEVYEDLMKAE------EAHQPKCPENDIRSCCLAEIKQTEEKYTETLESIEKYFMAPLKRFLTAAEFDSVFINIPELVKLHRNLMQEIHDSIVNKNDQNLYQVFINYKERLV-IYGQYCSGVESAISSLDYISKTKEDVKLKLEECSKRANNGKFTLRDLLVVPMQRVLKYHLLLQELVKHTTDPTEKANLKLALDAMKDLAQYVNEVKRDNETLREIKQFQLSIENLNQPVLLFGRPQGDGEIRITTLDKHTKQERHIFLFDLAVIVCKRKG---DNYEMKEIIDLQQYKIANNPTTDKENKKWSYGFYLIHTQGQNGLEFYCKTKDLKKKWLEQFEMALSNIRPDYADSNFHDFKMHTFTRVTSCKVCQMLLRGTFYQGYLCFKCGARAHKECLG 557
BLAST of EMLSAG00000000123 vs. GO
Match: - (symbol:VAV3 "Guanine nucleotide exchange factor VAV3" species:9606 "Homo sapiens" [GO:0005089 "Rho guanyl-nucleotide exchange factor activity" evidence=IEA] [GO:0035556 "intracellular signal transduction" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] Pfam:PF00169 InterPro:IPR000219 InterPro:IPR001331 InterPro:IPR001715 InterPro:IPR002219 InterPro:IPR028530 Pfam:PF00130 Pfam:PF00621 PROSITE:PS00479 PROSITE:PS00741 PROSITE:PS50010 PROSITE:PS50021 PROSITE:PS50081 SMART:SM00033 SMART:SM00109 SMART:SM00325 InterPro:IPR001849 GO:GO:0007264 Gene3D:2.30.29.30 InterPro:IPR011993 SMART:SM00233 PROSITE:PS50003 GO:GO:0046872 GO:GO:0005089 Gene3D:1.20.900.10 SUPFAM:SSF48065 Gene3D:1.10.418.10 SUPFAM:SSF47576 GO:GO:0032319 InterPro:IPR003096 PRINTS:PR00888 InterPro:IPR022613 Pfam:PF11971 EMBL:AC114491 PANTHER:PTHR22826:SF53 EMBL:AL391235 EMBL:AL353892 EMBL:AL513206 EMBL:AL591042 HGNC:HGNC:12659 ChiTaRS:VAV3 ProteinModelPortal:H0YDG2 Ensembl:ENST00000490388 UCSC:uc010oux.1 NextBio:35522065 Uniprot:H0YDG2) HSP 1 Score: 162.155 bits (409), Expect = 4.073e-41 Identity = 139/583 (23.84%), Postives = 244/583 (41.85%), Query Frame = 0
Query: 30 CVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDA---ETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGL-----NIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHCLGKIDVVEKTIKLMQLPRGAQLSD----------------------------FGRLRKAGELTAEN-SYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPL---FHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIG 571
C WL + KV+P H++ T ++++ D +RDGVLLCQL+++L S+++ + SQ F+C NI FL A F + E FE DL+ ++ G VIETLS LS + + FP +E N+E+IY + ++ + + E +YD +Y +D +Y+ + + E R + E+ TE+KY E L + F L L++ + + +F + EL++LH ++ + N + ++F+ + +YG YC + ++ + + K ++ +L C +A F L L++P QR LK ++ ++V H + + L + AQ + FGR + GE+ + + FLFD +++C R Y + + ++ Y+I + + F+ I L F C+ ++ W + A+ + P H M TF TSC C ++ G F+QGY C +C A HK+C+G
Sbjct: 2 CAQWLIHCKVLPTNHRV--TWDSAQVFDLAQTLRDGVLLCQLLNNLRAHSINLKEINLRPQMSQ-------FLCLKNIRTFLTACCETFGMRKSE-LFEAFDLFDVRDFGKVIETLSRLSRTPIALATGIRPFPTEES------INDEDIYKGLPDLIDETLVEDEEDLYDC----VYG--EDEGGEVYEDLMKAE------EAHQPKCPENDIRSCCLAEIKQTEEKYTETLESIEKYFMAPLKRFLTAAEFDSVFINIPELVKLHRNLMQEIHDSIVNKNDQNLYQVFINYKERLV-IYGQYCSGVESAISSLDYISKTKEDVKLKLEECSKRANNGKFTLRDLLVVPMQRVLKYHLLLQELVKHTTDPTEKANLKLALDAMKDLAQYVNEVKRDNETLREIKQFQLSIENLNQPVLLFGRPQGDGEIRITTLDKHTKQERHIFLFDLAVIVCKRKG---DNYEMKEIIDLQQYKIANNPTTDKENKKWSYGFYLIHTQGQNGLEFYCKTKDLKKKWLEQFEMALSNIRPDYADSNFHDFKMHTFTRVTSCKVCQMLLRGTFYQGYLCFKCGARAHKECLG 552
BLAST of EMLSAG00000000123 vs. GO
Match: - (symbol:VAV2 "Uncharacterized protein" species:9823 "Sus scrofa" [GO:0005089 "Rho guanyl-nucleotide exchange factor activity" evidence=IEA] [GO:0005154 "epidermal growth factor receptor binding" evidence=IEA] [GO:0005737 "cytoplasm" evidence=IEA] [GO:0005886 "plasma membrane" evidence=IEA] [GO:0007264 "small GTPase mediated signal transduction" evidence=IEA] [GO:0016477 "cell migration" evidence=IEA] [GO:0030032 "lamellipodium assembly" evidence=IEA] [GO:0043552 "positive regulation of phosphatidylinositol 3-kinase activity" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] Pfam:PF00017 Pfam:PF00169 InterPro:IPR000219 InterPro:IPR000980 InterPro:IPR001331 InterPro:IPR001452 InterPro:IPR001715 InterPro:IPR002219 InterPro:IPR028530 Pfam:PF00130 Pfam:PF00621 PRINTS:PR00401 PRINTS:PR00452 PROSITE:PS00479 PROSITE:PS00741 PROSITE:PS50001 PROSITE:PS50002 PROSITE:PS50010 PROSITE:PS50081 SMART:SM00109 SMART:SM00252 SMART:SM00325 SMART:SM00326 InterPro:IPR001849 GO:GO:0005886 GO:GO:0005737 GO:GO:0007264 Gene3D:2.30.29.30 Gene3D:3.30.505.10 InterPro:IPR011993 SMART:SM00233 PROSITE:PS50003 GO:GO:0046872 SUPFAM:SSF50044 GO:GO:0016477 GO:GO:0005089 Gene3D:1.20.900.10 SUPFAM:SSF48065 Gene3D:1.10.418.10 SUPFAM:SSF47576 GO:GO:0030032 GO:GO:0032319 InterPro:IPR011511 Pfam:PF07653 GO:GO:0043552 OMA:WFAGNME OrthoDB:EOG73FQKZ TreeFam:TF316171 PANTHER:PTHR22826:SF53 GeneTree:ENSGT00740000115307 EMBL:CU627992 EMBL:CU572088 Ensembl:ENSSSCT00000006315 Uniprot:F1S039) HSP 1 Score: 155.221 bits (391), Expect = 4.641e-38 Identity = 148/654 (22.63%), Postives = 270/654 (41.28%), Query Frame = 0
Query: 99 SDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYN--DTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTL-LSSKDKELIFYKLDELIRLHTEILTGLNIK----GSQVGEIFLRLNPIIARL--YGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHC--------------------------------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARLSD-YAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPL---FHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGSTNSNASSINNNG---LTKCDSVTLPTVINEPLERSEST-----LSLSPDSKQ--------------PSA-------DRVSKLQRETEEELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVRKR 678
S F+C NI FL F L E F+P DL+ ++ G VI +S LS N + + FP +E ++++++Y S++E+ + + +D+Y+ +D ++IY+ I + Q + ++ KR + E+ +TE KY L + + L L LS D +F L++LI++H L +++ G + ++FL +RL YG+YC H+ + + + L R ++ C K + F L L++P QR LK ++ +++ H L KI + +I+ +Q+ +L +FGR + GEL + D Y FLFD ++++C R + Y + +++ +++ +H + F+ I F C+ + W + A+ + P + H M TF++ TSC C + G F+QGY C +C HK+C+ P ++ S +S G + + +P +P+ ++ L P+S+ PS+ D + R E+ WFAG++ + L+S GT+L+R+R
Sbjct: 2 SQFLCLKNIRTFLKVCHDKFGLRNSE-LFDPFDLFDVRDFGKVISAVSRLSLHNLAQNKGIRPFPSEET-----AESDDDVYRSLEELADEHD-------LGEDVYDCVPCEDEGDDIYEDIIKVEVQ----QPMKMAMTEDDKRGCCLLEIQETEAKYYRTLEDIEKNYMAPLRLVLSPADMAAVFINLEDLIKVHHGFLRAIDVSMMAGGGTLAKVFLDFKERPSRLLIYGEYCSHMEHAQNTLNQLLASREDFRQKVEECTLKVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSTDRPEREQLKEALEAMQDLAMYINEVKRDKETLKKISEFQSSIENLQV----KLEEFGRPKIDGELKVRSIVNHTKQDRYLFLFDKVVIVCKRRGY---SYELKEVIELLFHKMTDDPMNHKDVKKWSYGFYLIHLQGKQGFQFFCKTEDMKRKWMEQFAMAMSNIRPDKATANHHSFQMHTFEKTTSCTACRMFLRGTFYQGYLCTKCGVGAHKECLEVTPPCKISSPADLDASGAGPGPKMVAVQNYHGIPAPPGKPVLTFQTGDVIELLRGDPESQWWEGRLVQTRKSGYFPSSSVKPCPVDGRPPMSRPPSREMDYTAY---PWFAGNMERQQTDNLLKSHASGTYLIRER 628
BLAST of EMLSAG00000000123 vs. C. finmarchicus
Match: gi|592819420|gb|GAXK01135148.1| (TSA: Calanus finmarchicus comp240255_c1_seq3 transcribed RNA sequence) HSP 1 Score: 185.652 bits (470), Expect = 4.201e-53 Identity = 100/173 (57.80%), Postives = 126/173 (72.83%), Query Frame = 0
Query: 26 LWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGD--AETEYIY 196
LWKEC+AWL FKVIP GH +L T + D V L+RDGV+LCQLVH LDPSSVDMT+V+Y++PE++ + SDF+CR+NIFLFL+A V+NF L+TD+HFFEP LY ++I V+ TLSALSH K S + GFPKKEK L KKI+NEE IY S++ Y + E IY
Sbjct: 26 LWKECLAWLDKFKVIPRGHPVLAT--GAGPHDLVLLLRDGVILCQLVHCLDPSSVDMTQVVYASPEAE---AVSDFVCRNNIFLFLYAAVNNFQLDTDDHFFEPTALYQYKDISKVLRTLSALSHSTKFLASQISGFPKKEKKLEKKIQNEEQIYDSLRNYYNTVLSNNESIY 529
BLAST of EMLSAG00000000123 vs. C. finmarchicus
Match: gi|592819422|gb|GAXK01135146.1| (TSA: Calanus finmarchicus comp240255_c1_seq1 transcribed RNA sequence) HSP 1 Score: 179.874 bits (455), Expect = 6.771e-50 Identity = 100/284 (35.21%), Postives = 154/284 (54.23%), Query Frame = 0
Query: 339 EKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHC--------------------------------------------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQT-SPSHPNSIPLFHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLE 577
E+ +PKL+ +L CQ KA+ + FPL +H++LPFQR LK M+ +I+ H L ++ VE+TIK M LP GA+L DFGRLR+AG+L + G + +DY FL DTI+++C +P +Q RYRF++A+K+++YR+ +T + N+I LFHR+ P ++ + +++ + ++W KA+ ++D + P EN H L MT C C + G+ QGYRC+ C A+LHK CI D C E
Sbjct: 33 EQRNPKLKKELNKCQIKAK-SPFPLCAHIVLPFQRLLKYHIMLAEILKHTPETHEEYLDLELAHNHMKNFNSEVNEAKREQEDNEKQMIQDEKDLAILENVERTIKSMHLPNGAKLKDFGRLRRAGDLKVLSVSGDQ-TDYVFLLDTIMVMCNKPSIMQQRYRFKSALKLKEYRVEETRGGTAQNTIRLFHRMNLLSQP-IILLAKSSIELDLWLKALLTSMDFLYPSENKGSRHDLIMTNLP-ALECTACKKKFLGMIAQGYRCRGCHAILHKSCIPDLMCRE 872
BLAST of EMLSAG00000000123 vs. C. finmarchicus
Match: gi|592819430|gb|GAXK01135138.1| (TSA: Calanus finmarchicus comp240255_c0_seq2 transcribed RNA sequence) HSP 1 Score: 147.902 bits (372), Expect = 1.372e-39 Identity = 72/180 (40.00%), Postives = 114/180 (63.33%), Query Frame = 0
Query: 389 LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQT-SPSHPNSIPLFHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHK 567
L ++ VE+TIK M LP GA+L DFGRLR+AG+L + G + +DY FL DTI+++C +P +Q RYRF++A+K+++YR+ +T + N+I LFHR+ P ++ + +++ + ++W KA+ ++D + P EN H L MT C C + G+ QGYRC+ C A+LHK
Sbjct: 73 LAILENVERTIKSMHLPNGAKLKDFGRLRRAGDLKVLSVSGDQ-TDYVFLLDTIMVMCNKPSIMQQRYRFKSALKLKEYRVEETRGGTAQNTIRLFHRMNLLSQP-IILLAKSSIELDLWLKALLTSMDFLYPSENKGSRHDLIMTNL-PALECTACKKKFLGMIAQGYRCRGCHAILHK 603
BLAST of EMLSAG00000000123 vs. C. finmarchicus
Match: gi|592819421|gb|GAXK01135147.1| (TSA: Calanus finmarchicus comp240255_c1_seq2 transcribed RNA sequence) HSP 1 Score: 139.813 bits (351), Expect = 1.422e-36 Identity = 95/209 (45.45%), Postives = 125/209 (59.81%), Query Frame = 0
Query: 129 PEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGD--AETEYIYDSFAKDIYN-----DTQDN-YENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQL-TLLSSKDKELIFYKLDELIRLHTEILTGLNIKGSQVGEIFLRLNPIIARLYGDYCVHL 328
P LY ++I V+ TLSALSH K S + GFPKKEK L KKI+NEE IY S++ Y + E IY D + + DN Y++IYQTIC+P+ R SL+I S KSKR+ PI E +TEDKYL NLIMVRD F Q+ LL E+IF++L ELI LH++IL L + S +G++ L+ +Y DYC +L
Sbjct: 3 PTALYQYKDISKVLRTLSALSHSTKFLASQISGFPKKEKKLEKKIQNEEQIYDSLRNYYNTVLSNNESIYSPQKVDPKSPIKEAEIPDNIYDDIYQTICSPRKSRMSLDI---SFSKKSKREYPIKEFSETEDKYLANLIMVRDNFLSQMQNLLQPNMVEIIFFRLHELITLHSDILLDLKKRKSNIGQVILKYRQDF-EVYKDYCTNL 617
BLAST of EMLSAG00000000123 vs. C. finmarchicus
Match: gi|592819431|gb|GAXK01135137.1| (TSA: Calanus finmarchicus comp240255_c0_seq1 transcribed RNA sequence) HSP 1 Score: 107.842 bits (268), Expect = 2.543e-25 Identity = 66/196 (33.67%), Postives = 98/196 (50.00%), Query Frame = 0
Query: 271 TLLSSKDKELIFYKLDELIRLHTEILTGLNIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHC--------------------------------------------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGEL 422
LL E+IF++L ELI LH++IL L + S +G++ L+ +Y DYC +L + + E+ +PKL+ +L CQ KA+ + FPL +H++LPFQR LK M+ +I+ H L ++ VE+TIK M LP GA+L DFGRLR+AG+L
Sbjct: 23 NLLQPNMVEIIFFRLHELITLHSDILLDLKKRKSNIGQVILKYRQDF-EVYKDYCTNLSHAQAVLEAEEQRNPKLKKELNKCQIKAK-SPFPLCAHIVLPFQRLLKYHIMLAEILKHTPETHEEYLDLELAHNHMKNFNSEVNEAKREQEDNEKQMIQDEKDLAILENVERTIKSMHLPNGAKLKDFGRLRRAGDL 604
BLAST of EMLSAG00000000123 vs. C. finmarchicus
Match: gi|592819418|gb|GAXK01135150.1| (TSA: Calanus finmarchicus comp240255_c1_seq5 transcribed RNA sequence) HSP 1 Score: 104.76 bits (260), Expect = 8.090e-25 Identity = 72/150 (48.00%), Postives = 91/150 (60.67%), Query Frame = 0
Query: 129 PEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGD--AETEYIYDSFAKDIYN-----DTQDN-YENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQL 270
P LY ++I V+ TLSALSH K S + GFPKKEK L KKI+NEE IY S++ Y + E IY D + + DN Y++IYQTIC+P+ R SL+I S KSKR+ PI E +TEDKYL NLIMVR+ F Q+
Sbjct: 2 PTALYQYKDISKVLRTLSALSHSTKFLASQISGFPKKEKKLEKKIQNEEQIYDSLRNYYNTVLSNNESIYSPQKVDPKSPIKEAEIPDNIYDDIYQTICSPRKSRMSLDI---SFSKKSKREYPIKEFSETEDKYLANLIMVRENFLSQM 442
BLAST of EMLSAG00000000123 vs. C. finmarchicus
Match: gi|592819426|gb|GAXK01135142.1| (TSA: Calanus finmarchicus comp240255_c0_seq6 transcribed RNA sequence) HSP 1 Score: 71.633 bits (174), Expect = 1.825e-13 Identity = 44/128 (34.38%), Postives = 62/128 (48.44%), Query Frame = 0
Query: 339 EKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHC--------------------------------------------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGEL 422
E+ +PKL+ +L CQ KA+ + FPL +H++LPFQR LK M+ +I+ H L ++ VE+TIK M LP GA+L DFGRLR+AG+L
Sbjct: 10 EQRNPKLKKELNKCQIKAK-SPFPLCAHIVLPFQRLLKYHIMLAEILKHTPETHEEYLDLELAHNHMKNFNSEVNEAKREQEDNEKQMIQDEKDLAILENVERTIKSMHLPNGAKLKDFGRLRRAGDL 390
BLAST of EMLSAG00000000123 vs. C. finmarchicus
Match: gi|592819427|gb|GAXK01135141.1| (TSA: Calanus finmarchicus comp240255_c0_seq5 transcribed RNA sequence) HSP 1 Score: 71.633 bits (174), Expect = 1.971e-13 Identity = 44/128 (34.38%), Postives = 62/128 (48.44%), Query Frame = 0
Query: 339 EKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHC--------------------------------------------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGEL 422
E+ +PKL+ +L CQ KA+ + FPL +H++LPFQR LK M+ +I+ H L ++ VE+TIK M LP GA+L DFGRLR+AG+L
Sbjct: 22 EQRNPKLKKELNKCQIKAK-SPFPLCAHIVLPFQRLLKYHIMLAEILKHTPETHEEYLDLELAHNHMKNFNSEVNEAKREQEDNEKQMIQDEKDLAILENVERTIKSMHLPNGAKLKDFGRLRRAGDL 402
BLAST of EMLSAG00000000123 vs. C. finmarchicus
Match: gi|592920823|gb|GAXK01037552.1| (TSA: Calanus finmarchicus comp362769_c0_seq2 transcribed RNA sequence) HSP 1 Score: 66.2402 bits (160), Expect = 1.018e-11 Identity = 38/132 (28.79%), Postives = 67/132 (50.76%), Query Frame = 0
Query: 438 LFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIG-------QTSPSHPNSIPLFHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQ 562
+FD ++L+C + + Y F+ +K++DY++ T S L H+ H + LF R ++ W +AI +A + P + H M TF + +SC C++++ G+F+QGY CQ+CQ
Sbjct: 1 VFDKMLLICKQTR--GDHYSFKEGLKVQDYKVQDVSLRRLSTDARWAYSFMLVHKENLHA--YTLFA-RTEEEKNKWIEAIKEAQNNEVPSQRFNSTHDPLMHTFDKPSSCQYCHKLLKGLFYQGYLCQKCQ 381
BLAST of EMLSAG00000000123 vs. C. finmarchicus
Match: gi|592819423|gb|GAXK01135145.1| (TSA: Calanus finmarchicus comp240255_c0_seq9 transcribed RNA sequence) HSP 1 Score: 65.855 bits (159), Expect = 1.117e-11 Identity = 38/68 (55.88%), Postives = 47/68 (69.12%), Query Frame = 0
Query: 121 NTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYG 188
+TD+HFFEP LY ++I V+ TLSALSH K S + GFPKKEK L KKI+NEE IY S++ Y
Sbjct: 2 DTDDHFFEPTALYQYKDISKVLRTLSALSHSTKFLASQISGFPKKEKKLEKKIQNEEQIYDSLRNYYN 205
BLAST of EMLSAG00000000123 vs. L. salmonis peptides
Match: EMLSAP00000000123 (pep:novel supercontig:LSalAtl2s:LSalAtl2s101:528275:535129:-1 gene:EMLSAG00000000123 transcript:EMLSAT00000000123 description:"snap_masked-LSalAtl2s101-processed-gene-5.13") HSP 1 Score: 1410.59 bits (3650), Expect = 0.000e+0 Identity = 679/679 (100.00%), Postives = 679/679 (100.00%), Query Frame = 0
Query: 1 MDRFCEINPDDRLRIGGNTQSFNMVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTLLSSKDKELIFYKLDELIRLHTEILTGLNIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHCLGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPLFHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGSTNSNASSINNNGLTKCDSVTLPTVINEPLERSESTLSLSPDSKQPSADRVSKLQRETEEELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVRKRK 679
MDRFCEINPDDRLRIGGNTQSFNMVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTLLSSKDKELIFYKLDELIRLHTEILTGLNIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHCLGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPLFHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGSTNSNASSINNNGLTKCDSVTLPTVINEPLERSESTLSLSPDSKQPSADRVSKLQRETEEELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVRKRK
Sbjct: 1 MDRFCEINPDDRLRIGGNTQSFNMVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTLLSSKDKELIFYKLDELIRLHTEILTGLNIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHCLGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPLFHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGSTNSNASSINNNGLTKCDSVTLPTVINEPLERSESTLSLSPDSKQPSADRVSKLQRETEEELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVRKRK 679
BLAST of EMLSAG00000000123 vs. L. salmonis peptides
Match: EMLSAP00000003826 (pep:novel supercontig:LSalAtl2s:LSalAtl2s2071:1578:3887:1 gene:EMLSAG00000003826 transcript:EMLSAT00000003826 description:"maker-LSalAtl2s2071-snap-gene-0.3") HSP 1 Score: 114.005 bits (284), Expect = 2.471e-27 Identity = 93/345 (26.96%), Postives = 160/345 (46.38%), Query Frame = 0
Query: 176 EENIYSSMKEIYGDAETEYIY-----DSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTLLSSKDKELIFYKLDELIRLHTEILTGL--NIKG---SQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNS------------------------EMIIDIVIHC---------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGEL---TAENSYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSP 474
EE IY ++++I + + + Y + Y+ D E IYQ +C+ ++ + E+ +++ K KRD I E+I+TE Y++ L M+R F +T + DK++IF + EL H L I+G ++GE+FL + YG+YC LP+S D + + K D +R + + + F L L +P QR LK E ++D+ + L I +E +I +P G +L D+GRLRK GEL + ++ G + F+FD ++L+C +P H Y ++ ++K+ DY++ P
Sbjct: 42 EEQIYRTLEDIINEDKYQEFYFKHHGAAGKSHYYSGEDDKEEGIYQDLCSLQSLKIRAEL---NIQPKEKRDYCIKEIIETESNYVDVLNMLRKNFIKTITKMRDTDKKIIFMNIIELGDTHAGFYQNLCDVIRGKSCKKIGEVFLEYKTRFLK-YGEYCSCLPKSQDVLDNVMK-DEXVREXIALYEKSVKDGKFRLRDLLAVPMQRILKYHLLLKGLLDTTKPTHEEYRIIQQAYESMLDVSDYINEVKRDSEQLHIIKEIEASINDWNMPDGYELKDYGRLRKDGELKVHSHDSHAGKTKLRFVFIFDKVMLMC-KPARGDH-YSYKDSLKLADYKVQDERP 379
BLAST of EMLSAG00000000123 vs. L. salmonis peptides
Match: EMLSAP00000009074 (pep:novel supercontig:LSalAtl2s:LSalAtl2s56:477026:514584:1 gene:EMLSAG00000009074 transcript:EMLSAT00000009074 description:"maker-LSalAtl2s56-snap-gene-5.8") HSP 1 Score: 63.5438 bits (153), Expect = 1.140e-10 Identity = 67/255 (26.27%), Postives = 116/255 (45.49%), Query Frame = 0
Query: 238 KSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTLLSSKDKELIFYKLDELIRLHTEI----LTGLNIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKE-DPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIV----IHC------------LGKIDVVEKT---IKLMQLPRGAQLSDFGRL--RKAGELTAENSYGARL-------SDYAFLFDTIILLCTRPKWLQHRYRFR 459
K++R+ I+EL+ TE +Y+ +L V +RD+L + ++K +IF LDE+ H+ I L + + + F + LY YC ++P + + L E P + L+ CQ +A PL+S+L+ P QR K M+ D+V + C L I VV + + + LP+ +S G L ++T+EN +++ + FL+D IL+C Y+F+
Sbjct: 339 KTRRENIISELLSTESRYVSDLESVLLNYRDKLVIANNK-ANIIFGNLDEIHDFHSNILYPDLERCGVXPAAIARTFSACCQDLKTLYCAYCQNMPSARQAVAELGGEATPSI---LYQCQTEA-GHQLPLSSYLLKPMQRLTKYQLMLRDLVESSNVVCGKEDLDDALSSLLNVIKVVNDSLNEVNIKGLPKA--VSPLGSLVAHDVFQVTSENKSQSQILFRNRSQRRHVFLYDNHILICKPVNEKTQNYQFK 586
BLAST of EMLSAG00000000123 vs. SwissProt
Match: gi|21759460|sp|Q9NHV9.2|VAV_DROME (RecName: Full=Protein vav; Short=DroVav; Short=dVAV) HSP 1 Score: 213.772 bits (543), Expect = 2.766e-58 Identity = 202/722 (27.98%), Postives = 319/722 (44.18%), Query Frame = 0
Query: 17 GNTQSFNMVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKR--SSVPGF-----PKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTLLSSKDK-ELIFYKLDELIRLHTEILTGL------NIKGSQVGEIFLRL-NPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK------------------------NSEMIIDI------VIHCLGKIDVVEKT------IKLMQLPRGAQLSDFGRLRKAGEL--TAENSYGARLSDYAFLFDTIILL--CTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHP---NSIPLFHRIVPHPTPHLLFV--CRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGSTNSNASSINNNGLTKCDSVTLPTVINEPLERSESTLSLSPDSKQPSADRVSKLQRETEEELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVRKR 678
G N LW+ECVAWL KVIPP HK Q ++++ +RDGVLLC LV LDPSS+D R P+ + F+C NI LFL +NF + D FEP LY N V+ TLS LS C KV++ + GF P + H ++E IY K+++ + Y+ T E +YQ +CA R S SS S +RD I ELIDTE YL+ L ++ F L ++D+ LIF ++ EL+ +HT+ L L N K ++ ++FL P + +YG++C L ++D++ + K++ + + C+ L L +P QR LK E +ID+ V + +++K I L+Q G+ L +GRL GEL A +L YAF+FD I+++ K +Y +R + + DYR+ Q+ ++ + ++ + F ++ +R+ WRKA+T+A++ +EP H + + TF T+C C++ + G QGYRC+ CQ +HK C I++ G K + V++P P DR + +WFAG+++ +TA+ RL++ +GT+L+R R
Sbjct: 11 GGVAGVNGDLWRECVAWLTRCKVIPPDHKAAQP--DAEIRILAMTLRDGVLLCNLVIHLDPSSLD-PREFNRKPQ------MAQFLCSKNIKLFLDVCHNNFGIR-DADLFEPTMLYDLTNFHRVLITLSKLSQCRKVQQLHPDLIGFNLQLSPTERSH------SDEAIY---KDLHSTTTDNIACNGTG---YDHTNTKEEEVYQDLCA--LHRTSRSQTASS-TSFEQRDYVIRELIDTESNYLDVLTALKTKFMGPLERHLNQDELRLIFPRIRELVDIHTKFLDKLRESLTPNAK-VKMAQVFLDFREPFL--IYGEFCSLLLGAIDYLADVCKKNQIIDQLVQKCERDYNVGKLQLRDILSVPMQRILKYHLLLDKLVKETSPLHDDYRSLERAKEAMIDVSQYINEVKRDSDHLVIIQKVKDSICDIHLLQNGNGSDLLQYGRLLLDGELHIKAHEDQKTKLR-YAFVFDKILIMVKALHIKTGDMQYTYRDSHNLADYRVEQSHSRRTIGRDTRFKYQLLLARKSGKTAFTLYLKSEHERDKWRKALTEAMESLEPPGCQSTDHKMEIYTFDAPTTCRHCSKFLKGRIHQGYRCKVCQISVHKGC------------------ISSTGRCKQNPVSVPP---------------------PVCDR---------------QLSEFNWFAGNMDRETAAHRLENRRIGTYLLRVR 649
BLAST of EMLSAG00000000123 vs. SwissProt
Match: gi|2494862|sp|Q60992.1|VAV2_MOUSE (RecName: Full=Guanine nucleotide exchange factor VAV2; Short=VAV-2) HSP 1 Score: 200.29 bits (508), Expect = 2.711e-53 Identity = 152/601 (25.29%), Postives = 268/601 (44.59%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYN--DTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTL-LSSKDKELIFYKLDELIRLHTEILTGLNIK----GSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHC--------------------------------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARLSD-YAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPL----FHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGS 580
M W++C WL + KV+PP H+++ ++ + D +RDGVLLCQL+H+L P S+D+ + + SQ F+C NI FL F L E F+P DL+ ++ G VI +S LS + + + FP +E +N++++Y S++E+ + + +DIY+ +D ++IY+ I + Q + + KR + E+ +TE KY L + + L L LS D +F L++LI++H L +++ GS + ++FL + +YG+YC H+ + + L R ++ C + + F L L++P QR LK ++ +++ H L KI + +I+ +Q+ +L +FGR + GEL + D Y FLFD ++++C R + Y + +++ +++ P H I F+ I F C+ + W + A+ ++P + H M TF + T+C C + G F+QGY C RC HK+C+ P ++ S
Sbjct: 1 MEQWRQCGRWLIDCKVLPPNHRVVWP--SAVVFDLAQALRDGVLLCQLLHNLSPGSIDLKDINFRPQMSQ-------FLCLKNIRTFLKVCHDKFGLRNSE-LFDPFDLFDVRDFGKVISAVSRLSLHSIAQSKGIRPFPSEET-----AENDDDVYRSLEELADEHD-------LGEDIYDCVPCEDEGDDIYEDIIKVEVQ----QPMKMGMTEDDKRSCCLLEIQETEAKYYRTLEDIEKNYMGPLRLVLSPADMAAVFINLEDLIKVHHSFLRAIDVSMMAGGSTLAKVFLEFKERLL-IYGEYCSHMEHAQSTLNQLLASREDFRQKVEECTLRVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSADRPERQQLKEALEAMQDLAMYINEVKRDKETLKKISEFQCSIENLQV----KLEEFGRPKIDGELKVRSIVNHTKQDRYLFLFDKVVIVCKRKG---YSYELKEVIELLFHKM-TDDPMHNKDIKKWSYGFYLIHLQGKQGFQFFCKTEDMKRKWMEQFEMAMSNIKPDKANANHHSFQMYTFDKTTNCKACKMFLRGTFYQGYLCTRCGVGAHKECLEVIPPCKMSS 566
BLAST of EMLSAG00000000123 vs. SwissProt
Match: gi|212287930|sp|P52735.2|VAV2_HUMAN (RecName: Full=Guanine nucleotide exchange factor VAV2; Short=VAV-2) HSP 1 Score: 199.904 bits (507), Expect = 4.923e-53 Identity = 177/733 (24.15%), Postives = 310/733 (42.29%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYN--DTQDNYENIYQTICAPKTQRFSLEIFGS-SLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTL-LSSKDKELIFYKLDELIRLHTEILTGLNIK----GSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHC--------------------------------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARLSD-YAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRI-------GQTSPSHPNSIPL-FHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDY-PCLEVGSTNSNASSI----------NNNG---------LTKCDSVTLPTVINEP---------LERSESTLSLSPDSKQPSADRVSKLQRETEEELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVRKR 678
M W++C WL + KV+PP H+++ ++ + D +RDGVLLCQL+H+L P S+D+ + + SQ F+C NI FL F L E F+P DL+ ++ G VI +S LS + + + FP +E +N++++Y S++E+ + + +DIY+ +D ++IY+ I + Q+ + + KR+ + E+ +TE KY L + + L L LS D +F L++LI++H L +++ GS + ++FL + +YG+YC H+ + + + L R ++ C K + F L L++P QR LK ++ +++ H L KI + +I+ +Q+ +L +FGR + GEL + D Y FLFD ++++C R + Y + +++ +++ SH F+ I F C+ + W + A+ ++P + H M TF + T+C C + G F+QGY C +C HK+C+ PC + +AS N +G LT L + +P ++ +S S K D + R E I WFAG++ + L+S GT+L+R+R
Sbjct: 1 MEQWRQCGRWLIDCKVLPPNHRVVWP--SAVVFDLAQALRDGVLLCQLLHNLSPGSIDLKDINFRPQMSQ-------FLCLKNIRTFLKVCHDKFGLRNSE-LFDPFDLFDVRDFGKVISAVSRLSLHSIAQNKGIRPFPSEET-----TENDDDVYRSLEELADEHD-------LGEDIYDCVPCEDGGDDIYEDIIKVEVQQPMIRYMQKMGMTEDDKRNCCLLEIQETEAKYYRTLEDIEKNYMSPLRLVLSPADMAAVFINLEDLIKVHHSFLRAIDVSVMVGGSTLAKVFLDFKERLL-IYGEYCSHMEHAQNTLNQLLASREDFRQKVEECTLKVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSAERPERQQLKEALEAMQDLAMYINEVKRDKETLRKISEFQSSIENLQV----KLEEFGRPKIDGELKVRSIVNHTKQDRYLFLFDKVVIVCKRKG---YSYELKEIIELLFHKMTDDPMNNKDVKKSHGKMWSYGFYLIHLQGKQGFQFFCKTEDMKRKWMEQFEMAMSNIKPDKANANHHSFQMYTFDKTTNCKACKMFLRGTFYQGYMCTKCGVGAHKECLEVIPPCKFTSPADLDASGAGPGPKMVAMQNYHGNPAPPGKPVLTFQTGDVLELLRGDPESPWWEGRLVQTRKSGYFPSSSVKPCPVDGRPPISRPPSRE---IDYTAYPWFAGNMERQQTDNLLKSHASGTYLIRER 700
BLAST of EMLSAG00000000123 vs. SwissProt
Match: gi|122132317|sp|Q08DN7.1|VAV_BOVIN (RecName: Full=Proto-oncogene vav) HSP 1 Score: 181.415 bits (459), Expect = 6.711e-47 Identity = 183/729 (25.10%), Postives = 306/729 (41.98%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDA--ETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGL-----NIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIH----------------------CLGKIDVVEKTIKLM---QLP---RGAQLSDFGRLRKAGELTAEN-SYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPLFHRIV-----PHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDY-PCLEVGSTNSNA------------SSINNNGLTKCDSVTLPTVINEPLERSESTLSLSP----------------DSKQPSADRVSKLQRETEEELINIPVERQS---WFAGDLNPKTASVRLQSLPVGTFLVRKR 678
M LW++C WL +V+PP H++ T +++ + +RDGVLLCQL+++L P ++++ V SQ F+C NI FL F L E FE DL+ Q+ G VI TLSALS + + FP +E +E+IYS + + D E E +YD + + + YE++ ++ P + + KR + E+ TE+KY + L ++ F L L +D E+IF +++L+R+HT L + N S + ++F++ +YG YC + + + + ++ +L C +A F L L++P QR LK ++ ++V H C+ ++ +T++ + QL L+ +GR + GEL + +++ YAFL D +L+C R Y + V + +++ S ++ H + L F R + W + A+ + P+ GH M +F+E TSC C ++ G F+QGYRCQRC+A HK+C+G PC G S N GL K + + P L L+P + + S + V + ++ P + S W+AG + A L + GTFLVR+R
Sbjct: 1 MELWRQCTHWLIQCRVLPPSHRV--TWDGAQVCELAQALRDGVLLCQLLNNLLPHAINLREVNLRPQMSQ-------FLCLKNIRTFLSTCYEKFGLKRSE-LFEAFDLFDVQDFGKVIYTLSALSWTPIAQNKGIMPFPTEES------VGDEDIYSGLSDQIDDTVEEDEDLYDCVENE-EAEGDEVYEDLMRSEPVPMPPKMT---------EYDKRCCCLREIQQTEEKYTDTLGSIQQHFMKPLQRFLKPQDVEIIFINIEDLLRVHTHFLKEMKEALANPGASTLYQVFIKYKERFL-IYGRYCSQVESASKHLDRVATAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQDAMEKDNLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLAHYGRPKIDGELKITSVERRSKMDRYAFLLDKALLICKRRG---DTYDLKDFVNLHSFQVRDDSSGERDNKKWTHMFLLIEDQGAQGYELFFKTRELKKK--WMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCQRCRAPAHKECLGRVPPCGRHGQDYSGTMKKDKPHRRAQDKKRNELGLPKMEVCQEYYGLPPPPGAIGPFLRLNPGDIVELTKAEAEQNWWEGRNISTNEVGWFPCNRVKPYVHGPPQDLSVHLWYAGPMERAGAESILTNRSDGTFLVRQR 697
BLAST of EMLSAG00000000123 vs. SwissProt
Match: gi|1718102|sp|P54100.1|VAV_RAT (RecName: Full=Proto-oncogene vav; AltName: Full=p95) HSP 1 Score: 181.03 bits (458), Expect = 1.139e-46 Identity = 157/593 (26.48%), Postives = 264/593 (44.52%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDA--ETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGLNIKGSQVG-----EIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIH----------------------CLGKIDVVEKTIKLM---QLP---RGAQLSDFGRLRKAGELTAENSYGARLSD-YAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPLFHRIV-----PHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYP 574
M LW++C WL +V+PP H++ T +++ + +RDGVLLCQL+++L P ++++ V SQ F+C NI FL F L E FE DL+ Q+ G VI TLSALS + + FP ++ L +E+IYS + + D E E +YD + + + YE++ ++ P + + KR + E+ TE+KY + L ++ F L L +D E IF ++EL+ +HT L L S G ++F++ +YG YC + ++ + + ++ +L C +A F L L++P QR LK ++ ++V H C+ ++ +T++ + QL L+++GR + GEL + +D YAFL D +L+C R Y + +V + +++ S ++ H + L F R + W + A+ + P+ GH M +F+E TSC C ++ G F+QGYRC RC+A HK+C+G P
Sbjct: 1 MELWRQCTHWLIQCRVLPPSHRV--TWEGAQVCELAQALRDGVLLCQLLNNLLPHAINLREVNLRPQMSQ-------FLCLKNIRTFLSTCCEKFGLKRSE-LFEAFDLFDVQDFGKVIYTLSALSWTPIAQNKGIMPFPTEDSALG-----DEDIYSGLSDQIDDTAEEDEDLYDCVENE-EAEGDEIYEDLMRSESVPTPPKMT---------EYDKRCCCLREIQQTEEKYTDTLGSIQQHFMKPLQRFLKPQDMETIFVNIEELLSVHTHFLKELKDALSGPGATMLYQVFIKYKERFL-VYGRYCSQVESAIKHLDQVATAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQDTTEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLANYGRPKIDGELKITSVERRSKTDRYAFLLDKALLICKRRG---DSYDLKASVNLHSFQVRDDSSGERDNKKWSHMFLLIEDQGAQGYELFFKTRELKKK--WMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCYRCRAPAHKECLGRVP 562
BLAST of EMLSAG00000000123 vs. SwissProt
Match: gi|137483|sp|P27870.1|VAV_MOUSE (RecName: Full=Proto-oncogene vav; AltName: Full=p95vav) HSP 1 Score: 179.489 bits (454), Expect = 3.644e-46 Identity = 157/593 (26.48%), Postives = 262/593 (44.18%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDA--ETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGLNIKGSQVG-----EIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIH----------------------CLGKIDVVEKTIKLM---QLP---RGAQLSDFGRLRKAGELTAENSYGARLSD-YAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPLFHRIV-----PHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYP 574
M LW++C WL +V+PP H++ T +++ + +RDGVLLCQL+++L P ++++ V SQ F+C NI FL F L E FE DL+ Q+ G VI TLSALS + + FP ++ L N+E+IYS + + D E E +YD + + + YE++ + P + + KR + E+ TE+KY + L ++ F L L +D E IF ++EL +HT L L + G ++F++ +YG YC + + + + ++ +L C +A F L L++P QR LK ++ ++V H C+ ++ +T++ + QL L+++GR + GEL + +D YAFL D +L+C R Y + +V + +++ S ++ H + L F R + W + A+ + P+ GH M +F+E TSC C ++ G F+QGYRC RC+A HK+C+G P
Sbjct: 1 MELWRQCTHWLIQCRVLPPSHRV--TWEGAQVCELAQALRDGVLLCQLLNNLLPQAINLREVNLRPQMSQ-------FLCLKNIRTFLSTCCEKFGLKRSE-LFEAFDLFDVQDFGKVIYTLSALSWTPIAQNKGIMPFPTEDSAL-----NDEDIYSGLSDQIDDTAEEDEDLYDCVENE-EAEGDEIYEDLMRLESVPTPPKMT---------EYDKRCCCLREIQQTEEKYTDTLGSIQQHFMKPLQRFLKPQDMETIFVNIEELFSVHTHFLKELKDALAGPGATTLYQVFIKYKERFL-VYGRYCSQVESASKHLDQVATAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQDATEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLANYGRPKIDGELKITSVERRSKTDRYAFLLDKALLICKRRG---DSYDLKASVNLHSFQVRDDSSGERDNKKWSHMFLLIEDQGAQGYELFFKTRELKKK--WMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCYRCRAPAHKECLGRVP 562
BLAST of EMLSAG00000000123 vs. SwissProt
Match: gi|13124807|sp|P15498.4|VAV_HUMAN (RecName: Full=Proto-oncogene vav) HSP 1 Score: 176.407 bits (446), Expect = 4.205e-45 Identity = 183/729 (25.10%), Postives = 310/729 (42.52%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDA--ETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHT----EILTGLNIKGS-QVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIH----------------------CLGKIDVVEKTIKLM---QLP---RGAQLSDFGRLRKAGELTAEN-SYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPLFHRIV-----PHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDY-PCLEVGST------------NSNASSINNNGLTKCDSVTLPTVINEPLERSESTLSLSPD-----SKQPSADRVSKLQRETEEELINIPVER--------------QSWFAGDLNPKTASVRLQSLPVGTFLVRKR 678
M LW++C WL +V+PP H++ T +++ + +RDGVLLCQL+++L P ++++ V SQ F+C NI FL F L E FE DL+ Q+ G VI TLSALS + + FP +E+ + +E+IYS + + D E E +YD + N+ + E IY+ + +++ S+ + KR + E+ TE+KY + L ++ F L L +D E+IF +++L+R+HT E+ L G+ + ++F++ +YG YC + + + + ++ +L C +A F L L++P QR LK ++ ++V H C+ ++ +T++ + QL L+ +GR + GEL + +++ YAFL D +L+C R Y + V + +++ S ++ H + L F R + W + A+ + P+ GH M +F+E TSC C ++ G F+QGYRC RC+A HK+C+G PC G + N GL K + + P L L+P +K + + + + E+ P R W+AG + A L + GTFLVR+R
Sbjct: 1 MELWRQCTHWLIQCRVLPPSHRV--TWDGAQVCELAQALRDGVLLCQLLNNLLPHAINLREVNLRPQMSQ-------FLCLKNIRTFLSTCCEKFGLKRSE-LFEAFDLFDVQDFGKVIYTLSALSWTPIAQNRGIMPFPTEEESVG-----DEDIYSGLSDQIDDTVEEDEDLYDC----VENEEAEGDE-IYEDLM--RSEPVSMP---PKMTEYDKRCCCLREIQQTEEKYTDTLGSIQQHFLKPLQRFLKPQDIEIIFINIEDLLRVHTHFLKEMKEALGTPGAANLYQVFIKYKERFL-VYGRYCSQVESASKHLDRVAAAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQEAMEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLAHYGRPKIDGELKITSVERRSKMDRYAFLLDKALLICKRRG---DSYDLKDFVNLHSFQVRDDSSGDRDNKKWSHMFLLIEDQGAQGYELFFKTRELKKK--WMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCHRCRASAHKECLGRVPPCGRHGQDFPGTMKKDKLHRRAQDKKRNELGLPKMEVFQEYYGLPPPPGAIGPFLRLNPGDIVELTKAEAEQNWWEGRNTSTNEIGWFPCNRVKPYVHGPPQDLSVHLWYAGPMERAGAESILANRSDGTFLVRQR 698
BLAST of EMLSAG00000000123 vs. SwissProt
Match: gi|51338829|sp|Q9R0C8.2|VAV3_MOUSE (RecName: Full=Guanine nucleotide exchange factor VAV3; Short=VAV-3) HSP 1 Score: 175.637 bits (444), Expect = 5.774e-45 Identity = 144/591 (24.37%), Postives = 256/591 (43.32%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDA---ETEYIYDSFAKDIYNDTQDNYENIYQTICA--PKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGL-----NIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHCLGKIDVVEKTIKLMQLPRGAQLSD----------------------------FGRLRKAGELTAEN-SYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPL---FHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIG 571
M WK+C WL + KV+PP H++ T ++++ D +RDGVLLCQL+++L P S+++ + SQ F+C NI FL A F + E FE DL+ ++ G VIETLS LS + + FP +E N+E+IY + ++ + + E +YD + ++ + YE++ + A PK+Q + R + E+ TE+KY E L + F L L++ + + +F + +L+++H ++ + N + ++F+ + +YG YC + ++ + + K ++ +L C +A F L L++P QR LK ++ ++V H ++ + L + AQ + FGR + GE+ + + FLFD +++C R Y + + ++ Y+I + + F+ I L F C+ ++ W + A+ + P H M TF TSC C ++ G F+QGY C +C A HK+C+G
Sbjct: 1 MEPWKQCAQWLIHSKVLPPNHRV--TWDSAQVFDLAQTLRDGVLLCQLLNNLRPHSINLKEINLRPQMSQ-------FLCLKNIRTFLAACCDTFGMRKSE-LFEAFDLFDVRDFGKVIETLSRLSRTPIALATGIRPFPTEES------INDEDIYKGLPDLIDETRVEDEEDLYDCVYGE--DEGGEVYEDLMKAEEAQQPKSQENDI------------RSCCLAEIRQTEEKYTETLESIEKYFMAPLKRFLTAAEFDSVFINIPDLVKVHRSLMQEIHDSIVNKDDQNLYQVFINYKERLV-IYGQYCSGVESAISNLDYISKTKEDVKLKLEECSKRANNGKFTLRDLLVVPMQRVLKYHLLLQELVKHTHDPMEKANLKLALDAMKDLAQYVNEVKRDNETLREIKQFQLSIENLNQPVLLFGRPQGDGEIRITTLDKHTKQERHIFLFDLAVIVCKRKG---DNYEMKEIIDLQQYKIANNPTTDKENKKWSYGFYLIHTQGQNGLEFYCKTKDLKKKWLEQFEMALSNIRPDYADSNFHDFKMHTFTRVTSCRVCQMLLRGTFYQGYLCFKCGAKAHKECLG 557
BLAST of EMLSAG00000000123 vs. SwissProt
Match: gi|12643372|sp|Q9UKW4.1|VAV3_HUMAN (RecName: Full=Guanine nucleotide exchange factor VAV3; Short=VAV-3) HSP 1 Score: 169.859 bits (429), Expect = 6.123e-43 Identity = 142/589 (24.11%), Postives = 248/589 (42.11%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDA---ETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGL-----NIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHCLGKIDVVEKTIKLMQLPRGAQLSD----------------------------FGRLRKAGELTAEN-SYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPL---FHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIG 571
M WK+C WL + KV+P H++ T ++++ D +RDGVLLCQL+++L S+++ + SQ F+C NI FL A F + E FE DL+ ++ G VIETLS LS + + FP +E N+E+IY + ++ + + E +YD +Y +D +Y+ + + E R + E+ TE+KY E L + F L L++ + + +F + EL++LH ++ + N + ++F+ + +YG YC + ++ + + K ++ +L C +A F L L++P QR LK ++ ++V H + + L + AQ + FGR + GE+ + + FLFD +++C R Y + + ++ Y+I + + F+ I L F C+ ++ W + A+ + P H M TF TSC C ++ G F+QGY C +C A HK+C+G
Sbjct: 1 MEPWKQCAQWLIHCKVLPTNHRV--TWDSAQVFDLAQTLRDGVLLCQLLNNLRAHSINLKEINLRPQMSQ-------FLCLKNIRTFLTACCETFGMRKSE-LFEAFDLFDVRDFGKVIETLSRLSRTPIALATGIRPFPTEES------INDEDIYKGLPDLIDETLVEDEEDLYDC----VYG--EDEGGEVYEDLMKAE------EAHQPKCPENDIRSCCLAEIKQTEEKYTETLESIEKYFMAPLKRFLTAAEFDSVFINIPELVKLHRNLMQEIHDSIVNKNDQNLYQVFINYKERLV-IYGQYCSGVESAISSLDYISKTKEDVKLKLEECSKRANNGKFTLRDLLVVPMQRVLKYHLLLQELVKHTTDPTEKANLKLALDAMKDLAQYVNEVKRDNETLREIKQFQLSIENLNQPVLLFGRPQGDGEIRITTLDKHTKQERHIFLFDLAVIVCKRKG---DNYEMKEIIDLQQYKIANNPTTDKENKKWSYGFYLIHTQGQNGLEFYCKTKDLKKKWLEQFEMALSNIRPDYADSNFHDFKMHTFTRVTSCKVCQMLLRGTFYQGYLCFKCGARAHKECLG 557
BLAST of EMLSAG00000000123 vs. SwissProt
Match: gi|115305910|sp|Q45FX5.1|VAV_CAEEL (RecName: Full=Protein vav-1) HSP 1 Score: 153.68 bits (387), Expect = 1.516e-37 Identity = 161/667 (24.14%), Postives = 269/667 (40.33%), Query Frame = 0
Query: 26 LWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLN-TDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENI--YQTICAPKT-----QRFSLEIFGSSLKSKS--------------KRDLPINELIDTEDKYL-ENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGLN--IKGS--------------------QVGEIFLRL-NPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQL--FTCQAKARPTTFPLTSHLILPFQRFLK------------------------NSEMIIDIV---------IHCLGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENS----YGARLSDYAFLFDTIILLC-----------TRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPLFHRIVPH------------PTPHLLFVCRNAADREVWRKAITDAVDVVEPKENA-ERGHVLAMTTF----KEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEV 578
LW C WL + KV L T N + +F +++RDG+LLC+L ++L P+ +D +++ + S F+C +NI F A+ Y N D F EDLY V++TLS LSH + V FP + N + S+ E D E IY DN EN+ +TI P T ++ S +++ + ++ KR+ I EL DTE Y+ + L+ + F + L ++ + D +IF ++E+ LHT +L L +K + +GE+F++ + +A YG YC +LP S L K + + + T Q + F + L +PFQR K E++ D+ + + ID +E++I + +P +L D+GR+ GE+ S G Y FLFD +I++C T + + ++ A + + I + + S R + L F +N A R W A+ + V P + + H +A +F K +C C+++M G+ +QGY+C+ C +HK+C+G C V
Sbjct: 39 LWIGCARWLRDMKV-------LTTDKNGTMLEFASVLRDGILLCRLANTLVPNGIDQKKIMRT-------NQPSPFLCCNNINYF--AMFCKTYFNLEDADLFTAEDLYYMNGFQKVLKTLSFLSHTKESLSRGVDPFPDTD--------NNQEGTSNGSEFEDDVE-----------IYQSLHDNIENVDPNRTIYGPITSADPEEQQSEQLYDRIVTNRKPSMNENDLQNTPTLKRNRCIRELYDTEKNYVAQALVTIIKTFYEPLKGIIPTSDYNIIFGNIEEINVLHTALLADLEYPVKVALGLSDATPPRPISLNECVPQTIGEVFIKYRDQFLA--YGKYCSNLPDSRKLSNELLKTNEFISRNINELTAQGNCK---FGMNDLLCVPFQRLTKYPLLLKELQKKTDLASPDRKSLEEAVEVMEDVCNYINEESRDTNAIKVIDEIEQSITDLSMPLNVKLHDYGRVNLDGEVKMAESTLTQAGKPKQRYIFLFDKVIVVCKAANKVMAAKTTGASARTNTFTYKNAYVMSELTIDKNASLDVKSGGTITRRTQYVIIMTRDRNENNEITQLTFYFKNEATRNNWMTALLLSKSNVSPTDYLRDTNHKVAFHSFRVDVKNPATCDVCDKLMKGLQYQGYKCESCNMSMHKECLGLKKCEAV 665
BLAST of EMLSAG00000000123 vs. Select Arthropod Genomes
Match: AAN09485.1 (Vav guanine nucleotide exchange factor, isoform B [Drosophila melanogaster]) HSP 1 Score: 213.772 bits (543), Expect = 1.341e-58 Identity = 202/722 (27.98%), Postives = 319/722 (44.18%), Query Frame = 0
Query: 17 GNTQSFNMVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKR--SSVPGF-----PKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTLLSSKDK-ELIFYKLDELIRLHTEILTGL------NIKGSQVGEIFLRL-NPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK------------------------NSEMIIDI------VIHCLGKIDVVEKT------IKLMQLPRGAQLSDFGRLRKAGEL--TAENSYGARLSDYAFLFDTIILL--CTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHP---NSIPLFHRIVPHPTPHLLFV--CRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGSTNSNASSINNNGLTKCDSVTLPTVINEPLERSESTLSLSPDSKQPSADRVSKLQRETEEELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVRKR 678
G N LW+ECVAWL KVIPP HK Q ++++ +RDGVLLC LV LDPSS+D R P+ + F+C NI LFL +NF + D FEP LY N V+ TLS LS C KV++ + GF P + H ++E IY K+++ + Y+ T E +YQ +CA R S SS S +RD I ELIDTE YL+ L ++ F L ++D+ LIF ++ EL+ +HT+ L L N K ++ ++FL P + +YG++C L ++D++ + K++ + + C+ L L +P QR LK E +ID+ V + +++K I L+Q G+ L +GRL GEL A +L YAF+FD I+++ K +Y +R + + DYR+ Q+ ++ + ++ + F ++ +R+ WRKA+T+A++ +EP H + + TF T+C C++ + G QGYRC+ CQ +HK C I++ G K + V++P P DR + +WFAG+++ +TA+ RL++ +GT+L+R R
Sbjct: 11 GGVAGVNGDLWRECVAWLTRCKVIPPDHKAAQP--DAEIRILAMTLRDGVLLCNLVIHLDPSSLD-PREFNRKPQ------MAQFLCSKNIKLFLDVCHNNFGIR-DADLFEPTMLYDLTNFHRVLITLSKLSQCRKVQQLHPDLIGFNLQLSPTERSH------SDEAIY---KDLHSTTTDNIACNGTG---YDHTNTKEEEVYQDLCA--LHRTSRSQTASS-TSFEQRDYVIRELIDTESNYLDVLTALKTKFMGPLERHLNQDELRLIFPRIRELVDIHTKFLDKLRESLTPNAK-VKMAQVFLDFREPFL--IYGEFCSLLLGAIDYLADVCKKNQIIDQLVQKCERDYNVGKLQLRDILSVPMQRILKYHLLLDKLVKETSPLHDDYRSLERAKEAMIDVSQYINEVKRDSDHLVIIQKVKDSICDIHLLQNGNGSDLLQYGRLLLDGELHIKAHEDQKTKLR-YAFVFDKILIMVKALHIKTGDMQYTYRDSHNLADYRVEQSHSRRTIGRDTRFKYQLLLARKSGKTAFTLYLKSEHERDKWRKALTEAMESLEPPGCQSTDHKMEIYTFDAPTTCRHCSKFLKGRIHQGYRCKVCQISVHKGC------------------ISSTGRCKQNPVSVPP---------------------PVCDR---------------QLSEFNWFAGNMDRETAAHRLENRRIGTYLLRVR 649
BLAST of EMLSAG00000000123 vs. Select Arthropod Genomes
Match: AAF48943.3 (Vav guanine nucleotide exchange factor, isoform A [Drosophila melanogaster]) HSP 1 Score: 213.772 bits (543), Expect = 1.341e-58 Identity = 202/722 (27.98%), Postives = 319/722 (44.18%), Query Frame = 0
Query: 17 GNTQSFNMVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKR--SSVPGF-----PKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTLLSSKDK-ELIFYKLDELIRLHTEILTGL------NIKGSQVGEIFLRL-NPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK------------------------NSEMIIDI------VIHCLGKIDVVEKT------IKLMQLPRGAQLSDFGRLRKAGEL--TAENSYGARLSDYAFLFDTIILL--CTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHP---NSIPLFHRIVPHPTPHLLFV--CRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGSTNSNASSINNNGLTKCDSVTLPTVINEPLERSESTLSLSPDSKQPSADRVSKLQRETEEELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVRKR 678
G N LW+ECVAWL KVIPP HK Q ++++ +RDGVLLC LV LDPSS+D R P+ + F+C NI LFL +NF + D FEP LY N V+ TLS LS C KV++ + GF P + H ++E IY K+++ + Y+ T E +YQ +CA R S SS S +RD I ELIDTE YL+ L ++ F L ++D+ LIF ++ EL+ +HT+ L L N K ++ ++FL P + +YG++C L ++D++ + K++ + + C+ L L +P QR LK E +ID+ V + +++K I L+Q G+ L +GRL GEL A +L YAF+FD I+++ K +Y +R + + DYR+ Q+ ++ + ++ + F ++ +R+ WRKA+T+A++ +EP H + + TF T+C C++ + G QGYRC+ CQ +HK C I++ G K + V++P P DR + +WFAG+++ +TA+ RL++ +GT+L+R R
Sbjct: 11 GGVAGVNGDLWRECVAWLTRCKVIPPDHKAAQP--DAEIRILAMTLRDGVLLCNLVIHLDPSSLD-PREFNRKPQ------MAQFLCSKNIKLFLDVCHNNFGIR-DADLFEPTMLYDLTNFHRVLITLSKLSQCRKVQQLHPDLIGFNLQLSPTERSH------SDEAIY---KDLHSTTTDNIACNGTG---YDHTNTKEEEVYQDLCA--LHRTSRSQTASS-TSFEQRDYVIRELIDTESNYLDVLTALKTKFMGPLERHLNQDELRLIFPRIRELVDIHTKFLDKLRESLTPNAK-VKMAQVFLDFREPFL--IYGEFCSLLLGAIDYLADVCKKNQIIDQLVQKCERDYNVGKLQLRDILSVPMQRILKYHLLLDKLVKETSPLHDDYRSLERAKEAMIDVSQYINEVKRDSDHLVIIQKVKDSICDIHLLQNGNGSDLLQYGRLLLDGELHIKAHEDQKTKLR-YAFVFDKILIMVKALHIKTGDMQYTYRDSHNLADYRVEQSHSRRTIGRDTRFKYQLLLARKSGKTAFTLYLKSEHERDKWRKALTEAMESLEPPGCQSTDHKMEIYTFDAPTTCRHCSKFLKGRIHQGYRCKVCQISVHKGC------------------ISSTGRCKQNPVSVPP---------------------PVCDR---------------QLSEFNWFAGNMDRETAAHRLENRRIGTYLLRVR 649
BLAST of EMLSAG00000000123 vs. Select Arthropod Genomes
Match: gb|KFM71930.1| (Guanine nucleotide exchange factor VAV2, partial [Stegodyphus mimosarum]) HSP 1 Score: 208.379 bits (529), Expect = 4.752e-57 Identity = 163/593 (27.49%), Postives = 276/593 (46.54%), Query Frame = 0
Query: 25 VLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYD-SFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENL-IMVRDVFRDQLTLLSSKDKELIFYKLDELIRLHT----EILTGLNIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNS------------------------EMIIDIVIH---------CLGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARLSD-YAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTS--PSHPNSIPL-FHRIVPHPT--PHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGD 572
LW+EC WL +V+ P H++ T ++++ D V +RDGVLLCQL++ L +D+ + SQ F+C NI FL + F + + + FEP L+ C + G V+ TLS LS +K + + + GFP K+ N+E IY +++EI E + + F + + E+IY+ +C T R ++ KRD I ELI+TE Y+E L ++++ R ++L++ +++IF + EL +HT E+ ++ E FL +YG+YC +LP + + + L + + + CQ +A F L L +P QR LK E ++D+ + L I ++ +I + +P +L D+GRL K GEL ++ RL + Y F+FD ++L+C + Q Y ++ A+ + DY++ + P N F+ ++ H L + + W +AI A+D V P H+ M +F + T+C C +++ G+F+QGY C C +HK CI D
Sbjct: 4 TLWRECADWLIKQQVLLPDHRV--TWPSAQVIDLVYTLRDGVLLCQLLNKLVIGCIDLKEISLRPQMSQ-------FLCLKNIRTFLQTCQNVFNIPSAD-LFEPAMLFDCTDFGKVLHTLSVLSKTDKAQAAGIKGFPSVIKN--HDYYNDE-IYRNLEEIANHNEEDTMVPLEFP---ISPRRSKEEDIYEDLCY-VTLRMREVSASQTVHPVEKRDYCIKELIETEKNYIEALNMIIKHFVRPLKSVLTADVRKVIFMNIKELAEIHTGFHSELYKACTSSHYKISECFLHWKDKFI-VYGEYCSNLPAAQERVEDLCNKSEVVNQAILRCQQEANGGKFKLRDLLSVPMQRILKYHLLLKELIRNTPKTHDDYFSLQKALEAMLDLAQYINEVKRDNETLQIIRDIQASITDLHMPDDLELKDYGRLLKDGELKIKSHDDHRLKNRYVFIFDKVMLMCKSTRGEQ--YSYKEALVLLDYKVEDVANTPKAGNRDKWSFYWLLAHKQNKTALTMYAKTEEMKRKWIEAIEKALDNVMPAALRSTDHIFQMHSFDKPTTCTECEKLLRGLFYQGYLCSVCGVAVHKDCIED 576
BLAST of EMLSAG00000000123 vs. Select Arthropod Genomes
Match: XP_006568541.1 (PREDICTED: protein vav isoform X2 [Apis mellifera]) HSP 1 Score: 203.756 bits (517), Expect = 4.444e-55 Identity = 164/605 (27.11%), Postives = 266/605 (43.97%), Query Frame = 0
Query: 19 TQSFNMVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICA---------PKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGLNIK--GSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK-------------------------NSEMIIDIVIH---------CLGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARL-SDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHP---NSIPLFHRIVPHPTPHLLFV--CRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIG 571
+ S N W ECV WL + HK P + + D +RDGVLLC L++++DP +DM V +Q F+C NI +FL A + F L TD FEP L+ + V+ TLSALS+C +++R + GF +++E+IY ++ G T + K D ++ +YQ + P T++ ++ KRD I EL++TE Y + L + F L+ LL +D IF+ + EL +H + L G+ + ++FL +YGDYC +L + + + + + ++ CQ +A F L L +P QR LK E+++DI + L I ++ +I +P QL DFGRL + GEL + RL + Y F+F+ ++L+C + Q Y +R +++ DYR+ + +S + ++ H + + R +++W KA+ DA+D V P H +TTF SC C + + G FQGYRC+ C +HK+CI
Sbjct: 6 SSSDNGSGWHECVKWLTRCGALRADHKA-NWPEATAV-DLAYTLRDGVLLCNLLNTVDPGCIDMKDVNQKPQMAQ-------FLCLRNIKVFLSACSTIFGL-TDSELFEPSMLFDLSDFLRVLRTLSALSNCPRLRRKGILGFSISHG------RSQEDIYKDLQSA-GAGPTTGVGTFTMKPKVMDVDES--QVYQELLCFSSNSQHDWPSTEK------DGAISGGEKRDYVIQELVETERNYSDVLNSLLKYFARPLSSLLRPEDSTRIFFGIKELAEIHAGFHSQLRKARTGAALAQVFLDWREKFL-IYGDYCANLTLAQNTLQEACARNELVNQEVIRCQQEANNGKFKLRDILSVPMQRVLKYHLLLDKLVEETPCDWLEDRRQLAKAREVMVDIAQYINEVKRDSDTLDIIRDIQASIIDWDVPEDTQLKDFGRLLRDGELKVKAHGDQRLKARYVFVFEQVVLICKAGRGEQ--YCYRETLRLDDYRLEDHTGRRTLGRDSRWSYQWLLVHKQEYTAYTLHARTEEQKQMWMKALQDAMDNVNPAACRNTNHKFKLTTFNTPRSCQRCGKFLKGRIFQGYRCEACCYAVHKQCIA 582
BLAST of EMLSAG00000000123 vs. Select Arthropod Genomes
Match: XP_006568540.1 (PREDICTED: protein vav isoform X1 [Apis mellifera]) HSP 1 Score: 202.986 bits (515), Expect = 9.470e-55 Identity = 167/617 (27.07%), Postives = 267/617 (43.27%), Query Frame = 0
Query: 19 TQSFNMVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDT------------QDNY---------ENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGLNIK--GSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK-------------------------NSEMIIDIVIH---------CLGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARL-SDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHP---NSIPLFHRIVPHPTPHLLFV--CRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIG 571
+ S N W ECV WL + HK P + + D +RDGVLLC L++++DP +DM V +Q F+C NI +FL A + F L TD FEP L+ + V+ TLSALS+C +++R + GF +++E+IY ++ E E F + N+ +D Y E IYQ +C+ ++ KRD I EL++TE Y + L + F L+ LL +D IF+ + EL +H + L G+ + ++FL +YGDYC +L + + + + + ++ CQ +A F L L +P QR LK E+++DI + L I ++ +I +P QL DFGRL + GEL + RL + Y F+F+ ++L+C + Q Y +R +++ DYR+ + +S + ++ H + + R +++W KA+ DA+D V P H +TTF SC C + + G FQGYRC+ C +HK+CI
Sbjct: 6 SSSDNGSGWHECVKWLTRCGALRADHKA-NWPEATAV-DLAYTLRDGVLLCNLLNTVDPGCIDMKDVNQKPQMAQ-------FLCLRNIKVFLSACSTIFGL-TDSELFEPSMLFDLSDFLRVLRTLSALSNCPRLRRKGILGFSISHG------RSQEDIYKDLQSAGAGREDEDRRRRFRRREGNEAGGGGDNEDPVEEEDGYGAYCSHAQSEEIYQDLCSLHLPPPPSVAQDGAISGGEKRDYVIQELVETERNYSDVLNSLLKYFARPLSSLLRPEDSTRIFFGIKELAEIHAGFHSQLRKARTGAALAQVFLDWREKFL-IYGDYCANLTLAQNTLQEACARNELVNQEVIRCQQEANNGKFKLRDILSVPMQRVLKYHLLLDKLVEETPCDWLEDRRQLAKAREVMVDIAQYINEVKRDSDTLDIIRDIQASIIDWDVPEDTQLKDFGRLLRDGELKVKAHGDQRLKARYVFVFEQVVLICKAGRGEQ--YCYRETLRLDDYRLEDHTGRRTLGRDSRWSYQWLLVHKQEYTAYTLHARTEEQKQMWMKALQDAMDNVNPAACRNTNHKFKLTTFNTPRSCQRCGKFLKGRIFQGYRCEACCYAVHKQCIA 603
BLAST of EMLSAG00000000123 vs. Select Arthropod Genomes
Match: gb|EEZ97169.2| (Protein vav-like Protein [Tribolium castaneum]) HSP 1 Score: 189.119 bits (479), Expect = 4.872e-50 Identity = 168/618 (27.18%), Postives = 268/618 (43.37%), Query Frame = 0
Query: 23 NMVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEI---LTGLNIKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK--------------NSEMIIDI------VIHCLGKIDVVEKTIKLMQLPRGAQ-------------LSDFGRLRKAGELTAENSYGARLSD-YAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPL-----FHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGSTNSNASS-INNNGLTKC 596
N LWKEC WL + ++ H+ P ++ ++D ++RDGVLLC+L++ + P +DM V +Q F+ HNI LFL V +F L D+ F+P L+ N V+ TLS LS + ++S++ GF + K K E+ IY S+K + + D IY+ E IYQ +CA + + F KRD I EL+DTE Y+E L ++ F L + +D E++FYK+ +L +H LT G ++ IF+ +YG YC +L R+ + + L D A + + + F L L +P QR LK N E D+ ++ G I+ + + + + + Q L ++GRL K GE+ + ++ + Y F+FD IL+C + K Q + FR + I +Y + T S FH + R ++ KAI DA+D + P H + TF C+ C++ + G+ +QGY+C C +HK CI GS N +++S + NG C
Sbjct: 12 NDELWKECSKWLTRWGMLRADHRA-NWP-DACIADLANILRDGVLLCKLLNKISPGCIDMKNVNLKPAMAQ-------FLSLHNIELFLKTCVISFGL-KDQDLFDPLVLFELTNFHKVLCTLSKLSLTKEAQKSNILGFTAQ----GVKTKEEDVIYQSLKSVEMPTNARGMNDP----IYDVAG---EEIYQDLCALRPVNEQPQTF-------EKRDFVIKELLDTEKNYVEVLAKLKRNFMKPLANQMKPQDHEVVFYKIYDLHEIHLAFYRELTRFRDPGFRLSSIFMNWRERFL-VYGGYCANLTRATNLLQELCDCDENFNATIVAYEKEDNNGRFKLRDVLSVPMQRILKYHLLLEKLIENTDPNDEECNDLRRAREAMLDVAGFINEAARDSEHLAVIQNLQENIVEWYRSPDHRLVNYGRLIKDGEMKIKAHDDQKIRNRYVFIFDKCILICKQIKVRQ--FAFRNIINISEYHVDDTHNRAVLSRDARFCYHFHLVKNDNVMVYTIFVRTLELKQQMIKAINDALDNIHPAAIKRTNHTFELQTFNGPVQCFHCSKYLRGLIYQGYKCGVCGIGVHKHCIAHSG--RCGSHNHHSTSDLVMNGADAC 596
BLAST of EMLSAG00000000123 vs. Select Arthropod Genomes
Match: EAA14588.5 (AGAP010292-PA, partial [Anopheles gambiae str. PEST]) HSP 1 Score: 189.119 bits (479), Expect = 5.193e-50 Identity = 162/595 (27.23%), Postives = 266/595 (44.71%), Query Frame = 0
Query: 26 LWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSS-VPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQL-TLLSSKDKELIFYKLDELIRLHTEILTGLN---IKGSQV--GEIFLRL-NPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK------------------------NSEMIIDIVIHC---------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARLSD-YAFLFDTIILLC--TRPKWLQHRYRFRTAVKIRDYRIGQTSPSHP---NSIPLFHRIVPHPTPHLLFV--CRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIG 571
LW+EC AWL +IP H+ +S + ++RDGVLLC L + DPSS D + P+ + F+C NI LFL A +NF L + FEP LY N V+ TLS LS C KV+ ++ +PGF ++ +++IY K+++ Y S +++ E +YQ +C+ Q S SS + +RD I EL+DTE YLE L ++ +F L LLS ++ IF + EL+ +H + L L+ GS++ FL P + +YG+YC + +++ + K+ + + Q + L L +P QR LK E ++D+ + L I V+++I + LP G L +GRL G+L + ++ YAF+F+ +++L + K + +Y FR A + DYRI + + + ++ T F + +RE W++A A++ +EP H + TF C C++ + G QGYRC+ C+ ++H+ CI
Sbjct: 15 LWRECAAWLTRCNIIPNDHR--ANHLDSDIKVLATILRDGVLLCNLANFFDPSSFD-RKDFNRKPQ------MAHFLCIQNIKLFLEACKTNFGLK-EADLFEPTMLYDLTNFHRVLLTLSKLSTCRKVQTATNIPGFITHSVQ-TERTSLDDDIY---KDLHASTSNPVEYCS-----HDEHDMKVEEVYQDLCS--IQNASRNQVSSSSNNLEQRDFVIKELLDTEKNYLEALNALKYIFMQPLEKLLSKEEIRAIFPCIRELVEIHNKFLDRLHEAVCPGSKLKLSTTFLEFREPFL--IYGEYCSSMTSAVETLREACKKSNTVEQTVLQSQKEHSDGRLQLRDILSVPMQRILKYHLLLDKLVQETVPTHDDFRGLERAKEAMVDVAQYSNEVKRDSEHLIVIQKVKESISDLNLPNGNNLEQYGRLLLDGDLNIKAHEDQKMKHRYAFVFEKVMILVKNSNTKIGEAQYSFREAHNLLDYRIEILNSRRTLGRDGRLKYSLLLARKTQATAFTLYMKTEEEREKWKRAFETAMETLEPVGCKNTDHKFVIHTFDTPVICRHCSKFLKGKIHQGYRCKVCEIVVHRGCIS 586
BLAST of EMLSAG00000000123 vs. Select Arthropod Genomes
Match: EEB17268.1 (protein vav, putative [Pediculus humanus corporis]) HSP 1 Score: 178.333 bits (451), Expect = 2.022e-46 Identity = 161/603 (26.70%), Postives = 263/603 (43.62%), Query Frame = 0
Query: 27 WKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSL-KSKSKRDLPINELIDTEDKYLENLI-MVRDVFRDQLTLLSSKDKELIFYKLDELIRLHTEILTGLNIKGSQVGEIFLRLNPIIAR------LYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK------------------------NSEMIIDIVIH---------CLGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGEL--TAENSYGARLSDYAFLFDTIILLCTRPKW-LQHRYRFRTAVKIRDYRIGQTSPS--HPNSIPLFHRIVPHPTPHLLFVC--RNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGST 581
W+EC WL ++ H + +K D +RDGV+LC L++ ++P +D V SQ R + F R F FL F L + F+P L+ + V++TLS LS K K+ ++ GF L K + + +Y + + Y S ++ N E IY +C+ R SL+ S+L S KRD INELI+TE YL+ L + R R +++ +D ++IF + EL +H LT L S G+I RL+ + +YGDY +L + + I L + ++ CQ +A F L L +P QR LK E ++D+ + L + +E++I +P L D+GRL GEL A N ++ Y F+FD ++++C K L +Y +R ++++ +Y+I ++ + + H + C R ++ + AI++A+D +EP H M TF+ T+C C++ + G +QGY+C++C HK CI C GST
Sbjct: 8 WRECADWLTRCGILRSDH--IANGAEAKARDLAVTLRDGVILCNLLNDIEPGCIDTKDV------SQKPRLSQVF--RVTTFFFLQTSHDTFGLKESD-LFDPVVLFDLTDFVKVLQTLSKLSLSPKFKKKNISGFS-----LIKHRSSHDELYKDLIHSNVLRAEDAEYSSHHVNMRN------EEIYHDLCS--INRISLQQIPSALPASLEKRDYVINELIETERNYLDVLGGLQRSFMRPLASIIREEDFKIIFAHIKELYEIHGVFLTQLRKAASPHGKI--RLSEVFLSFREKFLIYGDYIANLTNAQNLIQDLCGRSEMINNEVENCQQEANNGKFKLRDILSVPMQRILKYHLLLDKLVSETQMNHEDYRGLERAKEAMVDVAQYINEVKRDSDALAILAYIEQSISDWHMPPDFTLKDYGRLILDGELRIKAHNDQKQKVR-YVFVFDRVMVMCKALKTILGDQYCYRESLRLDEYKIQDIEKKILTRDARWSYQWYLVHRAELTAYTCYSRTEEFKKKFMNAISEALDNIEPSVCRNTEHNFKMFTFESPTTCSHCSKFLKGKIYQGYQCEKCHINCHKICIP--YCGRCGST 581
BLAST of EMLSAG00000000123 vs. Select Arthropod Genomes
Match: EFX75144.1 (hypothetical protein DAPPUDRAFT_323685 [Daphnia pulex]) HSP 1 Score: 178.333 bits (451), Expect = 2.235e-46 Identity = 177/718 (24.65%), Postives = 301/718 (41.92%), Query Frame = 0
Query: 15 IGGNTQSFNMVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKS-KRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGLNIKGSQVGE------IFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK--------------NSEMIIDIVIHCLGKIDVVEKT------IKLMQLPRGAQLS-------------DFGRLRKAGEL---TAENSYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNS-------IPLFHRIV----PHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGSTNS-NASSINNNGLTKCDSVTLPTVINEPLERSESTLSLSPDSKQPSADRVSKLQRETEEELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVR 676
+ G++Q + LW+ECV WL K++ Q P NS+L F IRDG +LC L+ LDP+++D V SQ ++ NI LFL A + F L D FEP L+ + G V+ TLS LS C+KV + + GFP + +++ ++ IY +++I E +Y ++A ENIY+ +C+ S + + KR+ I EL+++E +Y+E L M++ F L+ +L +K+ +F+ ++EL +HT + + L IK +FL +YG C +L + I ++ ++ CQ +A L + LP QR LK + E D+ + +D+ + T ++ Q+ + Q S ++GRL K GEL + E S A+ + Y FLF+ +Y F+ + + +++ HP S I H+ + + T + L+ ++A + W A ++ ++ + P E+ H TF SC+ C +++ G F QGYRC +C +H++C+G TNS +T P + LER WF+G++ A L++ P+GT+L+R
Sbjct: 1 MAGSSQ--RVPLWRECVDWLDRLKILRSD----QFPPNSELIHFGQCIRDGFILCYLITKLDPNALDFHDVCQRTQMSQ-------YMSLKNIRLFLRACRNKFDL-ADSDLFEPAMLFDYTDFGKVLRTLSKLSKCSKVTQKGIEGFPAVD---SRQYVEDDEIYRRLEDI-DQQEDQYCEYNYAV--------TGENIYEELCSVGEHNKSPQTHHPFPQPPVVKREYSIRELVESEKRYIEALSMIKTNFIVPLSSVLREDEKKCVFHGIEELHEIHTGLYSDL-IKACTTNNTIKLHMVFLNWKDKFL-IYGSICSNLSSARRAIKSAICRSREVAEKIERCQREASEVALNLEDLITLPMQRLLKYPLLLGNLCKHTEKSHEDYHDLQLAYEAMVDIADYTNESTRDYEMRQIIKDVQASISNWNTMENCDLVEYGRLIKDGELKMRSHEESRNAK-TRYVFLFNX-----------GDQYSFKLFLSLEKFKL----EDHPTSRNQNGREIRWSHQWLLVDNQNKTAYTLYA-KSAEAKNKWIGAFSETLEKLNPAESWGSDHNYEFHTFSNSISCHFCKKLLKGSFLQGYRCNKCSVSVHRECLG-------SMTNSCGVPIPPPRPRQIGAKLTSPAFHHIDLER-------------------------------------YPWFSGEMTRTAAEAVLRNTPLGTYLLR 629
BLAST of EMLSAG00000000123 vs. Select Arthropod Genomes
Match: XP_006568542.1 (PREDICTED: protein vav isoform X3 [Apis mellifera]) HSP 1 Score: 139.043 bits (349), Expect = 1.932e-33 Identity = 106/403 (26.30%), Postives = 175/403 (43.42%), Query Frame = 0
Query: 212 ENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLT-LLSSKDKELIFYKLDELIRLHTEILTGLNIK--GSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK-------------------------NSEMIIDIVIH---------CLGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARL-SDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHP---NSIPLFHRIVPHPTPHLLFV--CRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIG 571
E IYQ +C+ ++ KRD I EL++TE Y + L + F L+ LL +D IF+ + EL +H + L G+ + ++FL +YGDYC +L + + + + + ++ CQ +A F L L +P QR LK E+++DI + L I ++ +I +P QL DFGRL + GEL + RL + Y F+F+ ++L+C + Q Y +R +++ DYR+ + +S + ++ H + + R +++W KA+ DA+D V P H +TTF SC C + + G FQGYRC+ C +HK+CI
Sbjct: 69 EEIYQDLCSLHLPPPPSVAQDGAISGGEKRDYVIQELVETERNYSDVLNSLLKYFARPLSSLLRPEDSTRIFFGIKELAEIHAGFHSQLRKARTGAALAQVFLDWREKFL-IYGDYCANLTLAQNTLQEACARNELVNQEVIRCQQEANNGKFKLRDILSVPMQRVLKYHLLLDKLVEETPCDWLEDRRQLAKAREVMVDIAQYINEVKRDSDTLDIIRDIQASIIDWDVPEDTQLKDFGRLLRDGELKVKAHGDQRLKARYVFVFEQVVLICKAGRGEQ--YCYRETLRLDDYRLEDHTGRRTLGRDSRWSYQWLLVHKQEYTAYTLHARTEEQKQMWMKALQDAMDNVNPAACRNTNHKFKLTTFNTPRSCQRCGKFLKGRIFQGYRCEACCYAVHKQCIA 468
BLAST of EMLSAG00000000123 vs. nr
Match: gi|669193707|gb|AII16559.1| (vav 2 oncoprotein, partial [Paracyclopina nana]) HSP 1 Score: 619.387 bits (1596), Expect = 0.000e+0 Identity = 345/717 (48.12%), Postives = 453/717 (63.18%), Query Frame = 0
Query: 24 MVLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDI-YNDTQDNY--ENIYQTICAPKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQLTLLSSKDKELIFYKLDELIRLHTEILTGLNI-KGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK--------------------NSEMIIDIVIHCLGKID------------------------VVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNS--------IPLFHRIVPHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGSTNSNASSINNNGLTKCDSVTLPTVINEPLERSESTLSLSPDS----KQPSADR--VSKLQRETEEELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVRKR 678
M L +E AWL +FK+IPPG L+ N+ LSD +A++RDGV+LCQLVHSLDPSSV+M +VI E +GRS SDF+CR+NIFLFLHA V+NF L ++ F PEDLY C++IG V TLS LSH KV +S PGFPKKEK L K++KNE + Y +++++YG+A TEYIYDSFA I D +D Y E+IYQTI P+ R SL KSKR PI+EL+ TEDKYLENLIMVRDVFR++LT+++ +DK +IFY LD+LI LH++IL GL K +G++FLRL P I LYG YCVHLP +M + L + L+ Q+ CQA A P+TFPL+SHL++PFQRFLK N + +D +I +++ V TIKLM++ G L ++GRLR+AG++ + +G R+ DYAFLFD +I+LC RPKWLQHRYRFR A+KIRD + P H + LF + L V R+AADRE W AI A+D V P EN+++GHV+ +TTF E T C+ C +++ G FFQGY+C RCQA +HK C+ D CLEVG+ L K +S+ LPT + E LERS STLSL+P S K+ S R V +LQ E ++P++ Q W+AG+L+ KTAS RL+SLPVGTFL+RKR
Sbjct: 1 MELHREISAWLDHFKLIPPGSPALRP--NASLSDVIAVLRDGVVLCQLVHSLDPSSVEMHKVIC---EDGSGRSVSDFLCRNNIFLFLHAAVANFEL-SEGQLFHPEDLYQCRDIGKVFRTLSELSHTPKVLKSGAPGFPKKEKQLYKRLKNERSNYEALEQMYGEAGTEYIYDSFASKIRLRDQEDLYYNEDIYQTIFPPRQPRLSLADISFGGTKKSKRSAPIHELLTTEDKYLENLIMVRDVFREKLTIMNIQDKNIIFYLLDDLILLHSDILFGLKTPKKDDIGKVFLRLLPRITHLYGCYCVHLPMAMAHLEHLSQNYAPLKKQILECQAHANPSTFPLSSHLVIPFQRFLKYHLLLQEILKRTPDDHPDYVNLRLAVDEMIKAGEQVNEKKREQEEADQQDTKDEADMRLILSVSSTIKLMKMENGLNLLNYGRLRRAGDIVSYTDHG-RVGDYAFLFDLMIVLCHRPKWLQHRYRFREAIKIRDNFL--EPPIHHQQQQGQDVFCLRLFSKADARRVT-LTLVSRSAADREAWFDAILTAMDTVNPSENSQQGHVIQLTTFTEPTECFQCGKLLRGRFFQGYKCLRCQACMHKVCLADCACLEVGAP-----------LKKSNSLMLPTAMPESLERSTSTLSLAPSSENGNKRHSQIREVVQELQFNAIREQESLPLDEQPWYAGELDVKTASDRLESLPVGTFLIRKR 696
BLAST of EMLSAG00000000123 vs. nr
Match: gi|919059922|ref|XP_013411705.1| (PREDICTED: proto-oncogene vav-like isoform X6 [Lingula anatina]) HSP 1 Score: 229.18 bits (583), Expect = 1.296e-60 Identity = 167/599 (27.88%), Postives = 284/599 (47.41%), Query Frame = 0
Query: 26 LWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICA------PKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQL-TLLSSKDKELIFYKLDELIRLHTEILTGLN-----IKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNS------------------------EMIIDIVIHC---------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARL-SDYAFLFDTIILLC---TRPKWL-QHRYRFRTAVKIRDYRIGQTSPS-HPNSIPLFHRIVPHPTPHLL---FVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCI 570
LW+ C WL +++P H+++ N+++ D +RDGVLLC L+++L P +VDM SQ F+C NI FL + F L + F+ DL+ ++ V+ TLS LS S + GFP+ I+ E + Y++++E+ + E IY + ++ + IY+ +C+ + + + + K+KR+ + ELI+TE Y+E L M++ F L ++ S + ELIF ++ L +HT + L+ +G+ F++ P + LYGD+C +LP++ + I L +++ +R + CQ KA F L L +P QR LK E + D+ ++ L I ++ +I +Q+P L D+GRL K GEL ++ RL + Y FLFD ++L+C T K+L Y ++ A+ + +R+ + P+ P S H + + + F + + W AI A+D P E+GH MTTF+E +C C +++ G+F+QGY C RC+ +HK+CI
Sbjct: 6 LWRLCADWLIRCEILPRDHRVMFP--NAEIFDLAQTLRDGVLLCHLLNTLSPGAVDMKDFSQRPQMSQ-------FLCLKNIRTFLQTCKNKFGLRESD-LFDSYDLFDVKDFAKVLNTLSKLSKSELALASGIDGFPQDNS----SIQVEHDYYNTLEELATELPDEDIYSAVTT-----VEEGEQEIYEDLCSLRGRTTRRRKERERDQLEQGFEPKTKREHCLKELIETEKNYVEALQMIKTFFIHPLKNIIPSPNHELIFKHIEGLGNIHTAFQSDLHQAVRRSSAQALGDCFIKYKPQLL-LYGDFCSNLPQAQERIDDLCRKNEIIRVAVEECQRKANEGKFRLRDLLSVPVQRVLKYHLLLKELIKQTDKKSPDRTFLEKALEAMQDLSLYVNEVKRDNEQLQLIQEIQDSIVDLQMPEKTSLKDYGRLLKDGELKIKSHEDNRLKTRYIFLFDKVMLMCKSRTMEKFLWGETYSYKNALVLAQHRVEEGVPAGRPRSEKWGHVFLLSENKNSVAYNFYAKTEEMKMKWVDAIKMALDNTNPANAREKGHDFIMTTFEEPQTCSECKKLLRGVFYQGYNCHRCKQSVHKECI 584
BLAST of EMLSAG00000000123 vs. nr
Match: gi|391339789|ref|XP_003744229.1| (PREDICTED: protein vav [Galendromus occidentalis]) HSP 1 Score: 226.868 bits (577), Expect = 4.095e-60 Identity = 192/724 (26.52%), Postives = 316/724 (43.65%), Query Frame = 0
Query: 25 VLWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNY------ENIYQTIC-----APKTQRFSLEIFGSSLKSK-SKRDLPINELIDTEDKYLENLIMVRDVFRDQL-TLLSSKDKELIFYKLDELIRLHTEILTGLNIKG----SQVGEIFLRL-NPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK--------------------NSEMIIDIVIHCLGKIDVVEKTIKLMQ-------------LPRGAQLSDFGRLRKAGELTAENSYGARLSD-YAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPSHPNSIPLFHRIVPHPTPHLLFV-------------CRNAADREVWRKAITDAVDVVEPKENAERGHV-LAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGSTNSNASSINNNGLTKCDSVTLPTVINEP-LERSESTLSLSPDS-----KQPSADRVSKLQRETEEELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVR 676
VLW+E V WL + ++IP H++ T ++++ + +RDGV+LC L L P +D + SQ F+C NI FL A+ + F + + FEPE L+ + V+ +LS LS+ + + V GF K + N E Y + D T + SF + N + E IY IC APK + I L+ KRDL I EL++TE Y++ L M+R F+ L +S D +IF + L +HT +L L++ ++ E FLR N +I +YG+YC + PR+ + L ++ + + CQ + + L + L +P QR LK E +D ++ I+ V++ +++Q LP+ L D+GRL K GE+ ++ + + Y F+FD ++LLC K Q Y ++ A+ + YR+ P + +V + F+ + D+ W + I A+D ++P + H L MTTF+ + C CN++M GIF+QGY C RC +LH+ CI ++ S S S LP +N P + + + + ++ + V + EE+ + ++ WFAG ++ + A L+ P GTFLVR
Sbjct: 18 VLWREAVRWLVDLEMIPSDHRV--TWPDARVENLAYTLRDGVVLCNLALKLHPGCMDHKDMSLRPQMSQ-------FLCNKNIRAFLQALTNTFGITSPMDLFEPEMLFEYTDFKQVLHSLSVLSNSPEATKFGVKGFTA-----PKSVGNSE--YYNQSVFLKD--TPHNGTSFDTNGLNGHGPKHPRVTEEEEIYHKICVAPRSAPKPKTSERVIMIPILQVPLEKRDLCIQELLETEKNYIQALQMIRKKFQQPLEQAMSRDDAGVIFKHIRTLSDVHTGLLADLHVANQVPNGRISECFLRWKNSLI--IYGEYCSNYPRAQQLLQELLAKNDAVAQAIDKCQRETNDGRYQLNTLLCVPIQRVLKYHLLLKELVKNTLPQHDDYLGLEKALDAMLDLSAYINEVKRDSEMLQIIADIQNSITDYNLPKNVNLRDYGRLLKDGEVKVKSHKDQGVKNRYVFVFDQMLLLCKATKGDQ--YVYKEAISLSTYRVEDCQPMSGAASSSNSALVNAKSWQFQFLLVHLDQKTAYTIATKTLDDKLKWMEGIQKALDNLDPPAARQTDHERLDMTTFQAPSYCSHCNKLMKGIFYQGYSCSRCNKILHRDCIQHSKVCQIQSAAS--------------STPLPLSLNSPTIAVARNVIDVTRKVSVVLWEGRLGHNVGFFPAQYVEEIGQMNLDEHPWFAGTMSRERAEATLEPCPQGTFLVR 705
BLAST of EMLSAG00000000123 vs. nr
Match: gi|1101353468|ref|XP_018902786.1| (PREDICTED: protein vav isoform X2 [Bemisia tabaci]) HSP 1 Score: 223.402 bits (568), Expect = 3.111e-59 Identity = 197/701 (28.10%), Postives = 305/701 (43.51%), Query Frame = 0
Query: 26 LWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICAPKTQRFSLEIFGSSLKSKS--KRDLPINELIDTEDKYLENLIMVRDVF-RDQLTLLSSKDKELIFYKLDELIRLHTEILTGLNIKGS-----QVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK------------------------NSEMIIDIVIH---------CLGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGEL--TAENSYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRI---GQTSPSHPNSIPLFHRIVPHPTPHLLFV--CRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGSTNSNASSINNNGLTKCDSVTLPTVINEPLERSESTLSLSPDSKQPSADRVSKLQRETEEELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVRKR 678
+W+EC +WL V+ P HK + P + + D +RDGVLLC L+ SLDP +DM V +Q F+C NI +FL A ++Y + FEP L+ + VI TLS LS+C K ++ ++PGF H + + ++E+IY ++ D +Y DT + E IYQ +C+ Q+ + + S + KRD INEL++TE Y++ L ++ F R +L D +IF+ + EL +H L+ L + ++ E FL +YGDYC +L + D I + + + CQ +A F L L +P QR LK E +ID+ + L + ++ +I L +L DFGRL K GEL A N ++ Y F+FD +IL+C K Q Y F+ ++ +RDY+I G H S +H + + R ++ W KAI DA D +EP H +M TF+ T+C C++ + GI +QGYRC +C HK+C I+ G LP PL S+ ++ P + P S ++ + + + WF G + +TA L+ GTFL+R R
Sbjct: 5 VWRECASWLTRCGVLRPDHKA-KWP-EADIFDLALTLRDGVLLCNLISSLDPGCIDMKDVNQKPQLAQ-------FLCLRNIKVFLQA-CHDYYGLPESDLFEPLMLFDFTDFYRVIHTLSKLSNCPKFQKKNIPGF---SVHRPRTL-SQEDIYRNLNST-EDVSPRGAIGGEQYSMY-DTHAHNEEIYQDLCSIDKQKATNGTHVPTPISHNLEKRDYVINELVETEKNYVDVLGTLQKCFIRPLQNVLKDDDFRVIFWGIKELAEIHGGFLSQLRKATTPNSMIKLSETFLNWREKFL-IYGDYCANLTTAQDKIQEICNRSENINQLIQVCQEEANNNKFKLRDILSVPMQRILKYHLLLDKLISETQPNHEDYRGLERAKEAMIDVAQYINEVKKDSDTLQIMADIQASITDWSLAENMELRDFGRLIKDGELRIKAHNDQKVKVR-YVFIFDQVILMCKALKGDQ--YCFKESLMLRDYKIEDAGSKRILHRESRWNYHWFLLRKGERFAYTMYARTEELKKKWIKAIQDAFDNIEPSACRNTDHKFSMHTFERPTTCSHCSKFLKGIIYQGYRCDKCYLAAHKQC------------------ISFTGRCGLKPPQLPARHASPL--SDPLVAELPQAVPPLPSDWSWSPAQSSDHGLTDYL----WFVGSMGRETAERLLEWQMDGTFLLRIR 661
BLAST of EMLSAG00000000123 vs. nr
Match: gi|919059920|ref|XP_013411704.1| (PREDICTED: proto-oncogene vav-like isoform X5 [Lingula anatina]) HSP 1 Score: 224.172 bits (570), Expect = 6.238e-59 Identity = 166/599 (27.71%), Postives = 283/599 (47.25%), Query Frame = 0
Query: 26 LWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTICA------PKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQL-TLLSSKDKELIFYKLDELIRLHTEILTGLN-----IKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNS------------------------EMIIDIVIHC---------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARL-SDYAFLFDTIILLC---TRPKWL-QHRYRFRTAVKIRDYRIGQTSPS-HPNSIPLFHRIVPHPTPHLL---FVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCI 570
LW+ C WL +++P H+++ N+++ D +RDGVLLC L+++L P +VDM SQ F+C NI FL + F L + F+ DL+ ++ V+ TLS LS S + GFP L++ E++Y ++++ + E IY + ++ + IY+ +C+ + + + + K+KR+ + ELI+TE Y+E L M++ F L ++ S + ELIF ++ L +HT + L+ +G+ F++ P + LYGD+C +LP++ + I L +++ +R + CQ KA F L L +P QR LK E + D+ ++ L I ++ +I +Q+P L D+GRL K GEL ++ RL + Y FLFD ++L+C T K+L Y ++ A+ + +R+ + P+ P S H + + + F + + W AI A+D P E+GH MTTF+E +C C +++ G+F+QGY C RC+ +HK+CI
Sbjct: 6 LWRLCADWLIRCEILPRDHRVMFP--NAEIFDLAQTLRDGVLLCHLLNTLSPGAVDMKDFSQRPQMSQ-------FLCLKNIRTFLQTCKNKFGLRESD-LFDSYDLFDVKDFAKVLNTLSKLSKSELALASGIEGFPPD--RLSRVPSPVEDVYRTLEDRACELPDEDIYSAVTT-----VEEGEQEIYEDLCSLRGRTTRRRKERERDQLEQGFEPKTKREHCLKELIETEKNYVEALQMIKTFFIHPLKNIIPSPNHELIFKHIEGLGNIHTAFQSDLHQAVRRSSAQALGDCFIKYKPQLL-LYGDFCSNLPQAQERIDDLCRKNEIIRVAVEECQRKANEGKFRLRDLLSVPVQRVLKYHLLLKELIKQTDKKSPDRTFLEKALEAMQDLSLYVNEVKRDNEQLQLIQEIQDSIVDLQMPEKTSLKDYGRLLKDGELKIKSHEDNRLKTRYIFLFDKVMLMCKSRTMEKFLWGETYSYKNALVLAQHRVEEGVPAGRPRSEKWGHVFLLSENKNSVAYNFYAKTEEMKMKWVDAIKMALDNTNPANAREKGHDFIMTTFEEPQTCSECKKLLRGVFYQGYNCHRCKQSVHKECI 586
BLAST of EMLSAG00000000123 vs. nr
Match: gi|939246093|ref|XP_014242445.1| (PREDICTED: protein vav isoform X1 [Cimex lectularius]) HSP 1 Score: 221.861 bits (564), Expect = 9.283e-59 Identity = 191/716 (26.68%), Postives = 329/716 (45.95%), Query Frame = 0
Query: 26 LWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGDAETEYIYDSFAKDIYNDTQDNYENIYQTIC-----------APKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENL-IMVRDVFRDQLTLLSSKDKELIFYKLDELIRLHTEILTGLNIK---------GSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLK------------------------NSEMIIDIVIHCLGKIDVVEKTIKLMQ---------LPRGAQLSDFGRLRKAGELTAENSYGARLS-DYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTS---PSHPNSIPLFHRIV---PHPTPHLLFVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCIGDYPCLEVGSTNSNASSINNNGLTKCDSVTLPTVINEPLERSESTLSLSPDSKQPSADRVSKLQRETEE--ELINIPVERQSWFAGDLNPKTASVRLQSLPVGTFLVRKR 678
LW++CV+WL V+ P H+ P ++ L+D +RDGVLLC +H+L+P+S++M V SQ F+C NI F++A +F + + FEP L+ ++ VI TLS LS+ K++R ++ GF + + ++E+IY ++ G+ + S + + DTQ E IYQ +C AP T S E KRD INEL++TE Y++ L +++ R +++ D + IF + EL +H G +I+ G ++ E FL +YG+YC +L ++ I + + + + +L CQ +A F L L +P QR LK E ++D+ + + ++ T+++M + +L++FGRL K G+L ++ + ++ Y F+FD +++LC K ++ +Y F+ + + D+++ S H ++ +H + T + L+ R + W KAI DA+D +EP H +M TF + T+C C++ + GI FQGY+C++C HK CI N G +C S P + P ++ E LS+ P + ++D + R + EL+ WF G++ + AS L+S GT+L+R R
Sbjct: 5 LWRDCVSWLTRCGVLRPDHRA-NWP-DATLTDLAYTLRDGVLLCNFLHNLEPASIEMKDVNQKPQFSQ-------FLCLRNIKTFINACHYHFGMKESD-LFEPSMLFELTDLYRVIHTLSKLSNSPKLQRHNIEGFSIHKP----RTLSQEDIYRNLNSSGGEEGACAVDKSCVEFAHYDTQIRNEEIYQDLCCIDKHSTPVIYAPTTINHSFE----------KRDYVINELVETEKNYIDVLNTLLKHFIRPLTSIIKDDDMKTIFGGIKELYEIHM----GFHIQLLKAVTPGSGFKLSEAFLNWREQFL-VYGEYCANLTKAQSRIVEISRNEI-VNQKLIKCQQEANNGKFKLRDILSVPMQRILKYHLLLEKLISETQPNHEDFRGLERAREAMVDVAQY-INEVKRDSDTLQIMADIEESITDWESKQTKLTNFGRLLKDGDLRIKDHHIQKIKPRYVFIFDRVMILC---KAVRDQYSFKACLSLADFKVEDASCRKTLHRDARWNYHWYLVRKSESTAYTLYA-RTEDLKRKWIKAIQDALDNIEPAGCRSTDHNFSMHTFDKPTTCTHCSKFLKGIIFQGYKCEKCNLAAHKMCIV------------------NTG--RCGSRQPPELPPRP-DKPEQELSVHPIVPKSTSDVFPESCRTWTDHGELVEY-----LWFVGEMGREKASRLLESQVDGTYLLRIR 659
BLAST of EMLSAG00000000123 vs. nr
Match: gi|919059917|ref|XP_013411703.1| (PREDICTED: proto-oncogene vav-like isoform X4 [Lingula anatina]) HSP 1 Score: 221.09 bits (562), Expect = 8.991e-58 Identity = 167/616 (27.11%), Postives = 286/616 (46.43%), Query Frame = 0
Query: 26 LWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGD----------AETEYIYDSFA--------KDIYN---DTQDNYENIYQTICA------PKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQL-TLLSSKDKELIFYKLDELIRLHTEILTGLN-----IKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNS------------------------EMIIDIVIHC---------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARL-SDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQTSPS-HPNSIPLFHRIVPHPTPHLL---FVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCI 570
LW+ C WL +++P H+++ N+++ D +RDGVLLC L+++L P +VDM SQ F+C NI FL + F L + F+ DL+ ++ V+ TLS LS S + GFP+ I+ E + Y++++E+ + E +Y + +DIY+ ++ + IY+ +C+ + + + + K+KR+ + ELI+TE Y+E L M++ F L ++ S + ELIF ++ L +HT + L+ +G+ F++ P + LYGD+C +LP++ + I L +++ +R + CQ KA F L L +P QR LK E + D+ ++ L I ++ +I +Q+P L D+GRL K GEL ++ RL + Y FLFD ++L+C K Y ++ A+ + +R+ + P+ P S H + + + F + + W AI A+D P E+GH MTTF+E +C C +++ G+F+QGY C RC+ +HK+CI
Sbjct: 6 LWRLCADWLIRCEILPRDHRVMFP--NAEIFDLAQTLRDGVLLCHLLNTLSPGAVDMKDFSQRPQMSQ-------FLCLKNIRTFLQTCKNKFGLRESD-LFDSYDLFDVKDFAKVLNTLSKLSKSELALASGIDGFPQDNS----SIQVEHDYYNTLEELATGFPPDRLSRVPSPVEDVYRTLEDRACELPDEDIYSAVTTVEEGEQEIYEDLCSLRGRTTRRRKERERDQLEQGFEPKTKREHCLKELIETEKNYVEALQMIKTFFIHPLKNIIPSPNHELIFKHIEGLGNIHTAFQSDLHQAVRRSSAQALGDCFIKYKPQLL-LYGDFCSNLPQAQERIDDLCRKNEIIRVAVEECQRKANEGKFRLRDLLSVPVQRVLKYHLLLKELIKQTDKKSPDRTFLEKALEAMQDLSLYVNEVKRDNEQLQLIQEIQDSIVDLQMPEKTSLKDYGRLLKDGELKIKSHEDNRLKTRYIFLFDKVMLMC---KSRGETYSYKNALVLAQHRVEEGVPAGRPRSEKWGHVFLLSENKNSVAYNFYAKTEEMKMKWVDAIKMALDNTNPANAREKGHDFIMTTFEEPQTCSECKKLLRGVFYQGYNCHRCKQSVHKECI 603
BLAST of EMLSAG00000000123 vs. nr
Match: gi|919059913|ref|XP_013411701.1| (PREDICTED: proto-oncogene vav-like isoform X2 [Lingula anatina]) HSP 1 Score: 221.09 bits (562), Expect = 9.984e-58 Identity = 169/620 (27.26%), Postives = 289/620 (46.61%), Query Frame = 0
Query: 26 LWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGD----------AETEYIYDSFA--------KDIYN---DTQDNYENIYQTICA------PKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQL-TLLSSKDKELIFYKLDELIRLHTEILTGLN-----IKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNS------------------------EMIIDIVIHC---------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARL-SDYAFLFDTIILLC---TRPKWL-QHRYRFRTAVKIRDYRIGQTSPS-HPNSIPLFHRIVPHPTPHLL---FVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCI 570
LW+ C WL +++P H+++ N+++ D +RDGVLLC L+++L P +VDM SQ F+C NI FL + F L + F+ DL+ ++ V+ TLS LS S + GFP+ I+ E + Y++++E+ + E +Y + +DIY+ ++ + IY+ +C+ + + + + K+KR+ + ELI+TE Y+E L M++ F L ++ S + ELIF ++ L +HT + L+ +G+ F++ P + LYGD+C +LP++ + I L +++ +R + CQ KA F L L +P QR LK E + D+ ++ L I ++ +I +Q+P L D+GRL K GEL ++ RL + Y FLFD ++L+C T K+L Y ++ A+ + +R+ + P+ P S H + + + F + + W AI A+D P E+GH MTTF+E +C C +++ G+F+QGY C RC+ +HK+CI
Sbjct: 6 LWRLCADWLIRCEILPRDHRVMFP--NAEIFDLAQTLRDGVLLCHLLNTLSPGAVDMKDFSQRPQMSQ-------FLCLKNIRTFLQTCKNKFGLRESD-LFDSYDLFDVKDFAKVLNTLSKLSKSELALASGIDGFPQDNS----SIQVEHDYYNTLEELATGFPPDRLSRVPSPVEDVYRTLEDRACELPDEDIYSAVTTVEEGEQEIYEDLCSLRGRTTRRRKERERDQLEQGFEPKTKREHCLKELIETEKNYVEALQMIKTFFIHPLKNIIPSPNHELIFKHIEGLGNIHTAFQSDLHQAVRRSSAQALGDCFIKYKPQLL-LYGDFCSNLPQAQERIDDLCRKNEIIRVAVEECQRKANEGKFRLRDLLSVPVQRVLKYHLLLKELIKQTDKKSPDRTFLEKALEAMQDLSLYVNEVKRDNEQLQLIQEIQDSIVDLQMPEKTSLKDYGRLLKDGELKIKSHEDNRLKTRYIFLFDKVMLMCKSRTMEKFLWGETYSYKNALVLAQHRVEEGVPAGRPRSEKWGHVFLLSENKNSVAYNFYAKTEEMKMKWVDAIKMALDNTNPANAREKGHDFIMTTFEEPQTCSECKKLLRGVFYQGYNCHRCKQSVHKECI 610
BLAST of EMLSAG00000000123 vs. nr
Match: gi|919059915|ref|XP_013411702.1| (PREDICTED: protein vav-like isoform X3 [Lingula anatina]) HSP 1 Score: 220.705 bits (561), Expect = 1.071e-57 Identity = 169/620 (27.26%), Postives = 289/620 (46.61%), Query Frame = 0
Query: 26 LWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGD----------AETEYIYDSFA--------KDIYN---DTQDNYENIYQTICA------PKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQL-TLLSSKDKELIFYKLDELIRLHTEILTGLN-----IKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNS------------------------EMIIDIVIHC---------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARL-SDYAFLFDTIILLC---TRPKWL-QHRYRFRTAVKIRDYRIGQTSPS-HPNSIPLFHRIVPHPTPHLL---FVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCI 570
LW+ C WL +++P H+++ N+++ D +RDGVLLC L+++L P +VDM SQ F+C NI FL + F L + F+ DL+ ++ V+ TLS LS S + GFP+ I+ E + Y++++E+ + E +Y + +DIY+ ++ + IY+ +C+ + + + + K+KR+ + ELI+TE Y+E L M++ F L ++ S + ELIF ++ L +HT + L+ +G+ F++ P + LYGD+C +LP++ + I L +++ +R + CQ KA F L L +P QR LK E + D+ ++ L I ++ +I +Q+P L D+GRL K GEL ++ RL + Y FLFD ++L+C T K+L Y ++ A+ + +R+ + P+ P S H + + + F + + W AI A+D P E+GH MTTF+E +C C +++ G+F+QGY C RC+ +HK+CI
Sbjct: 6 LWRLCADWLIRCEILPRDHRVMFP--NAEIFDLAQTLRDGVLLCHLLNTLSPGAVDMKDFSQRPQMSQ-------FLCLKNIRTFLQTCKNKFGLRESD-LFDSYDLFDVKDFAKVLNTLSKLSKSELALASGIDGFPQDNS----SIQVEHDYYNTLEELATGFPPDRLSRVPSPVEDVYRTLEDRACELPDEDIYSAVTTVEEGEQEIYEDLCSLRGRTTRRRKERERDQLEQGFEPKTKREHCLKELIETEKNYVEALQMIKTFFIHPLKNIIPSPNHELIFKHIEGLGNIHTAFQSDLHQAVRRSSAQALGDCFIKYKPQLL-LYGDFCSNLPQAQERIDDLCRKNEIIRVAVEECQRKANEGKFRLRDLLSVPVQRVLKYHLLLKELIKQTDKKSPDRTFLEKALEAMQDLSLYVNEVKRDNEQLQLIQEIQDSIVDLQMPEKTSLKDYGRLLKDGELKIKSHEDNRLKTRYIFLFDKVMLMCKSRTMEKFLWGETYSYKNALVLAQHRVEEGVPAGRPRSEKWGHVFLLSENKNSVAYNFYAKTEEMKMKWVDAIKMALDNTNPANAREKGHDFIMTTFEEPQTCSECKKLLRGVFYQGYNCHRCKQSVHKECI 610
BLAST of EMLSAG00000000123 vs. nr
Match: gi|919059910|ref|XP_013411700.1| (PREDICTED: proto-oncogene vav-like isoform X1 [Lingula anatina]) HSP 1 Score: 220.705 bits (561), Expect = 1.224e-57 Identity = 169/620 (27.26%), Postives = 289/620 (46.61%), Query Frame = 0
Query: 26 LWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEIYGD----------AETEYIYDSFA--------KDIYN---DTQDNYENIYQTICA------PKTQRFSLEIFGSSLKSKSKRDLPINELIDTEDKYLENLIMVRDVFRDQL-TLLSSKDKELIFYKLDELIRLHTEILTGLN-----IKGSQVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNS------------------------EMIIDIVIHC---------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAENSYGARL-SDYAFLFDTIILLC---TRPKWL-QHRYRFRTAVKIRDYRIGQTSPS-HPNSIPLFHRIVPHPTPHLL---FVCRNAADREVWRKAITDAVDVVEPKENAERGHVLAMTTFKEETSCYCCNRIMAGIFFQGYRCQRCQALLHKKCI 570
LW+ C WL +++P H+++ N+++ D +RDGVLLC L+++L P +VDM SQ F+C NI FL + F L + F+ DL+ ++ V+ TLS LS S + GFP+ I+ E + Y++++E+ + E +Y + +DIY+ ++ + IY+ +C+ + + + + K+KR+ + ELI+TE Y+E L M++ F L ++ S + ELIF ++ L +HT + L+ +G+ F++ P + LYGD+C +LP++ + I L +++ +R + CQ KA F L L +P QR LK E + D+ ++ L I ++ +I +Q+P L D+GRL K GEL ++ RL + Y FLFD ++L+C T K+L Y ++ A+ + +R+ + P+ P S H + + + F + + W AI A+D P E+GH MTTF+E +C C +++ G+F+QGY C RC+ +HK+CI
Sbjct: 6 LWRLCADWLIRCEILPRDHRVMFP--NAEIFDLAQTLRDGVLLCHLLNTLSPGAVDMKDFSQRPQMSQ-------FLCLKNIRTFLQTCKNKFGLRESD-LFDSYDLFDVKDFAKVLNTLSKLSKSELALASGIDGFPQDNS----SIQVEHDYYNTLEELATGFPPDRLSRVPSPVEDVYRTLEDRACELPDEDIYSAVTTVEEGEQEIYEDLCSLRGRTTRRRKERERDQLEQGFEPKTKREHCLKELIETEKNYVEALQMIKTFFIHPLKNIIPSPNHELIFKHIEGLGNIHTAFQSDLHQAVRRSSAQALGDCFIKYKPQLL-LYGDFCSNLPQAQERIDDLCRKNEIIRVAVEECQRKANEGKFRLRDLLSVPVQRVLKYHLLLKELIKQTDKKSPDRTFLEKALEAMQDLSLYVNEVKRDNEQLQLIQEIQDSIVDLQMPEKTSLKDYGRLLKDGELKIKSHEDNRLKTRYIFLFDKVMLMCKSRTMEKFLWGETYSYKNALVLAQHRVEEGVPAGRPRSEKWGHVFLLSENKNSVAYNFYAKTEEMKMKWVDAIKMALDNTNPANAREKGHDFIMTTFEEPQTCSECKKLLRGVFYQGYNCHRCKQSVHKECI 610
BLAST of EMLSAG00000000123 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold693_size110418-snap-gene-0.23 (protein:Tk06977 transcript:maker-scaffold693_size110418-snap-gene-0.23-mRNA-1 annotation:"hypothetical protein YQE_10749 partial") HSP 1 Score: 97.0561 bits (240), Expect = 4.861e-21 Identity = 63/201 (31.34%), Postives = 100/201 (49.75%), Query Frame = 0
Query: 26 LWKECVAWLGNFKVIPPGHKLLQTPYNSKLSDFVALIRDGVLLCQLVHSLDPSSVDMTRVIYSAPESQTGRSASDFICRHNIFLFLHAIVSNFYLNTDEHFFEPEDLYLCQNIGNVIETLSALSHCNKVKRSSVPGFPKKEKHLAKKIKNEENIYSSMKEI----------YGDAETEYIYDSFAKDIYNDTQDNYENIYQ 216
LWK+C WL ++P H++ T ++K+ D +RDGVLLC + +LD SS+D+ +Q F+C NI LFL + + F L + F P LY + V+ TLS LS+C K K V GFP++ K + ++EE IY +++++ Y E Y + Y++ Q + E+IY+
Sbjct: 169 LWKQCADWLCRMDILPNNHRI--TWPDAKIQDLAYTLRDGVLLCHIAKALDESSLDLHSAHLRPQMAQ-------FLCLKNIRLFLQSCLDKFGLEETD-LFHPTMLYDYSDFARVLHTLSKLSNCAKAKAKEVNGFPQQYKEPS---QDEEQIYRTLEDMVNEDNYKAFYYDHHGAESAYGKMNRPYYSEGQKD-EDIYE 355 HSP 2 Score: 78.5666 bits (192), Expect = 2.891e-15 Identity = 53/202 (26.24%), Postives = 90/202 (44.55%), Query Frame = 0
Query: 305 QVGEIFLRLNPIIARLYGDYCVHLPRSMDFITVLEKEDPKLRAQLFTCQAKARPTTFPLTSHLILPFQRFLKNSEMIIDIVIHC---------------------------------LGKIDVVEKTIKLMQLPRGAQLSDFGRLRKAGELTAE--NSYGARLSDYAFLFDTIILLCTRPKWLQHRYRFRTAVKIRDYRIGQ 471
++GEIF+ + YGDYC LP++ + + L + +R ++ C+ A F L L +P QR LK ++ +++ + LG I+ +E +I LP G L D+GRL GEL + ++ G + F+FD IIL+C + Y ++ ++K+ DYR+ Q
Sbjct: 359 KIGEIFIEYKKRFLK-YGDYCSDLPKAQEALDALLNKAENVRDEITQCEQNANEGKFRLRDLLAVPMQRILKYHLLLRELLSNTPSTHEEHHTLKQAYEAMLDVSDFINEVKRDSEQLGIINEIESSITDWNLPEGVCLKDYGRLLSDGELKVQSHDTNGKTKLRFVFVFDKIILMCKATR--GDHYAYKNSLKLSDYRVEQ 557 The following BLAST results are available for this feature:
BLAST of EMLSAG00000000123 vs. GO
Analysis Date: 2014-04-02 (Blast vs. GO) Total hits: 25
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BLAST of EMLSAG00000000123 vs. C. finmarchicus
Analysis Date: 2014-05-09 (TblastN vs C. finmarchicus TSA) Total hits: 25
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BLAST of EMLSAG00000000123 vs. L. salmonis peptides
Analysis Date: 2014-05-10 (Blastp vs. self) Total hits: 3
BLAST of EMLSAG00000000123 vs. SwissProt
Analysis Date: 2017-02-10 (Blastp vs. SwissProt) Total hits: 13
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BLAST of EMLSAG00000000123 vs. Select Arthropod Genomes
Analysis Date: 2017-02-20 (Blastp vs. Selected Arthropods) Total hits: 23
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BLAST of EMLSAG00000000123 vs. nr
Analysis Date: 2017-02-20 (Blastp vs. NR (2/2017)) Total hits: 25
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BLAST of EMLSAG00000000123 vs. Tigriopus kingsejongenis genes
Analysis Date: 2018-04-18 (Blastp vs. Tigriopus kingsejongensis proteins) Total hits: 1
Alignments
The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Cross References
External references for this gene
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at LSalAtl2s101:528275..535129- Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>EMLSAG00000000123-682889 ID=EMLSAG00000000123-682889|Name=EMLSAG00000000123|organism=Lepeophtheirus salmonis|type=gene|length=6855bp|location=Sequence derived from alignment at LSalAtl2s101:528275..535129- (Lepeophtheirus salmonis)back to top Add to Basket
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