BLAST of EMLSAG00000000293 vs. GO
Match: - (symbol:TOP1MT "Uncharacterized protein" species:9031 "Gallus gallus" [GO:0003677 "DNA binding" evidence=IEA] [GO:0003917 "DNA topoisomerase type I activity" evidence=IEA] [GO:0003918 "DNA topoisomerase type II (ATP-hydrolyzing) activity" evidence=IEA] [GO:0005694 "chromosome" evidence=IEA] [GO:0006265 "DNA topological change" evidence=IEA] [GO:0042645 "mitochondrial nucleoid" evidence=IEA] InterPro:IPR001631 InterPro:IPR008336 InterPro:IPR011010 InterPro:IPR013030 InterPro:IPR013034 InterPro:IPR013499 InterPro:IPR013500 InterPro:IPR014711 InterPro:IPR014727 InterPro:IPR018521 Pfam:PF01028 Pfam:PF02919 PRINTS:PR00416 PROSITE:PS00176 SMART:SM00435 GO:GO:0005694 GO:GO:0003677 GO:GO:0006200 GO:GO:0006265 SUPFAM:SSF56349 GO:GO:0003918 GO:GO:0003917 OrthoDB:EOG7CVPX5 TreeFam:TF105281 Gene3D:1.10.10.41 Gene3D:1.10.132.10 Gene3D:2.170.11.10 Gene3D:3.90.15.10 InterPro:IPR025834 Pfam:PF14370 SUPFAM:SSF56741 GeneTree:ENSGT00390000016347 EMBL:AADN03002066 Ensembl:ENSGALT00000026012 PRO:PR:F1NXP4 Uniprot:F1NXP4)

HSP 1 Score: 579.326 bits (1492), Expect = 0.000e+0
Identity = 313/560 (55.89%), Postives = 391/560 (69.82%), Query Frame = 0

Query:  355 WEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLF--RGRYL-VGFMDRKYSK---------------------------SNQIRHVKSFL----------------KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            WEEEK +DG KWK L+H+GP F P Y+ LP  V FYY+ K +KLS  TEE+A FYA+ ++HEYT KE+F  NFF DWRK MT +E++II  L KCDFREI+ Y+   +E RK  SKEEK+  KE+   IQ+E+G C++D H EKIGNF+ EPPGLF  RG +  +G + ++                               N +  + S+                 K+K  K +  +E AR+LK  + KIR  Y  D+KSKEM+ RQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI LH+  DG+++ VEFDFLGKDSIRY+N V VEK VFKN+QLFM+NK   DDLFDRL+T +LN++L  LM GLTAKVFRT+NAS TLQ+QL+ LT  +D+V  K+LSYNRANR VAILCNHQR+ PKT +KSMQNLQ KI AK+E  EKA+++L++A+  +K+      +  + KKKK LER  EQL KL  QA DKEENK IALGTSKLNYLDPRIS+AW KKF VPIEK++NKTQR+KF WAI+M   D+ F
Sbjct:   34 WEEEKTNDGVKWKQLEHKGPYFVPLYEPLPDDVQFYYDGKPLKLSLATEEIATFYAKMLDHEYTTKEIFQNNFFNDWRKEMTPQEQEIIKQLDKCDFREIHKYFVDKNEARKALSKEEKQKLKEEADKIQEEYGYCILDGHREKIGNFKTEPPGLFRGRGDHPKMGMLKKRIMPEDVIINCSKDSKIPEPPVGHKWKEVRFDNTVTWLASWTENIQNSLKYIMLNPSSKLKGEKDWQKFEVARKLKDVVHKIRAQYQADWKSKEMKKRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHIKLHSKLDGQEHVVEFDFLGKDSIRYYNKVSVEKPVFKNLQLFMKNKDPGDDLFDRLSTAVLNKHLQKLMNGLTAKVFRTYNASITLQEQLKALTNPEDSVAGKLLSYNRANRAVAILCNHQRSTPKTFEKSMQNLQTKIDAKKEQLEKAQQELEEAEDEFKDKKDAKAEANVQKKKKLLERLKEQLAKLNVQATDKEENKQIALGTSKLNYLDPRISIAWCKKFGVPIEKIFNKTQREKFAWAIDMTDEDFEF 593          

BLAST of EMLSAG00000000293 vs. GO
Match: - (symbol:TOP1MT "Uncharacterized protein" species:9823 "Sus scrofa" [GO:0003677 "DNA binding" evidence=IEA] [GO:0003917 "DNA topoisomerase type I activity" evidence=IEA] [GO:0003918 "DNA topoisomerase type II (ATP-hydrolyzing) activity" evidence=IEA] [GO:0005694 "chromosome" evidence=IEA] [GO:0006265 "DNA topological change" evidence=IEA] InterPro:IPR001631 InterPro:IPR008336 InterPro:IPR011010 InterPro:IPR013030 InterPro:IPR013034 InterPro:IPR013499 InterPro:IPR013500 InterPro:IPR014711 InterPro:IPR014727 InterPro:IPR018521 Pfam:PF01028 Pfam:PF02919 PRINTS:PR00416 PROSITE:PS00176 SMART:SM00435 GO:GO:0005694 GO:GO:0003677 GO:GO:0006200 GO:GO:0006265 SUPFAM:SSF56349 GO:GO:0003918 GO:GO:0003917 OrthoDB:EOG7CVPX5 TreeFam:TF105281 Gene3D:1.10.10.41 Gene3D:1.10.132.10 Gene3D:2.170.11.10 Gene3D:3.90.15.10 InterPro:IPR025834 Pfam:PF14370 SUPFAM:SSF56741 GeneTree:ENSGT00390000016347 EMBL:CU655901 Ensembl:ENSSSCT00000029650 OMA:VVINCSX Uniprot:I3LTP0)

HSP 1 Score: 579.326 bits (1492), Expect = 0.000e+0
Identity = 294/560 (52.50%), Postives = 383/560 (68.39%), Query Frame = 0

Query:  355 WEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKY------------------SKSNQIRHVKS-------------------FLKIK-----RGKGYYEK---ARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDE-DQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            WEEE+   G +W  L+HRGP FAP Y+ LP GV FYY+ K MKLS   EEVA FY + +EHEYT KEVF  NFF+DWRK MT  ER +I  LSKCDF EI+ ++   +  R+   +EEK+  KE+   +Q EFG C++D H EKIGNF+ EPPGLFRGR     +G + R+                      +Q + V+S                   ++ +      +G+  +EK   AR LK  +++IR  Y  D+KS+EM+ RQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEH+ LH   DG  Y VEFDFLGKDSIRY+N VPVEK V++N+QLF+ENK   ++LFDRL T  LN++L  LM GLTAKVFRT+NAS TLQ QL  LT A+D++ AK+LSYNRANR VA+LCNHQRA PKT +KSMQ L+ KI+AK++   +A+ +L++A+  + +      +  ++K+++ LE+  EQL +L TQA DKEE K +ALGTSKLNYLDPRIS+AW ++F VP+EK+YNKTQR+KF WA++MAG D+ F
Sbjct:   46 WEEERSPRGVRWTQLEHRGPCFAPPYEPLPDGVRFYYDGKPMKLSLAAEEVATFYGKMLEHEYTTKEVFRHNFFRDWRKEMTAAERKVIKRLSKCDFTEIHRHFADRAAARRALPREEKQRLKEEAEKLQQEFGYCILDGHREKIGNFKTEPPGLFRGRGDHPKMGMLKRRVLPEDVTINCGRDSKVPEPPAGHQWKEVRSDRTVTWLAAWTENVQNATKYVMLNPSSKLKGERDWEKYEVARRLKGVVDEIRSRYRADWKSREMKARQRAVALYFIDKLALRAGNEKEEGESADTVGCCSLRVEHVQLHPEADGCPYVVEFDFLGKDSIRYYNKVPVEKPVYRNLQLFLENKDPGEELFDRLTTASLNKHLQDLMDGLTAKVFRTYNASITLQGQLRALTRAEDSIAAKLLSYNRANRAVAVLCNHQRAPPKTFEKSMQALRSKIEAKKQQVAEAKAELEKARAGHASREDGRMQFFLEKRRRRLEKLEEQLVRLGTQATDKEEGKQVALGTSKLNYLDPRISIAWCRRFGVPVEKIYNKTQREKFAWALDMAGEDFEF 605          

BLAST of EMLSAG00000000293 vs. GO
Match: - (symbol:Top1mt "DNA topoisomerase 1, mitochondrial" species:10090 "Mus musculus" [GO:0000166 "nucleotide binding" evidence=IEA] [GO:0003677 "DNA binding" evidence=IEA] [GO:0003916 "DNA topoisomerase activity" evidence=IEA] [GO:0003917 "DNA topoisomerase type I activity" evidence=IBA] [GO:0003918 "DNA topoisomerase type II (ATP-hydrolyzing) activity" evidence=IEA] [GO:0005524 "ATP binding" evidence=IEA] [GO:0005634 "nucleus" evidence=ISO] [GO:0005694 "chromosome" evidence=IEA] [GO:0005739 "mitochondrion" evidence=ISO;IDA] [GO:0006260 "DNA replication" evidence=IBA] [GO:0006265 "DNA topological change" evidence=IBA] [GO:0016853 "isomerase activity" evidence=IEA] [GO:0042645 "mitochondrial nucleoid" evidence=ISO;IBA] InterPro:IPR001631 InterPro:IPR008336 InterPro:IPR011010 InterPro:IPR013030 InterPro:IPR013034 InterPro:IPR013499 InterPro:IPR013500 InterPro:IPR014711 InterPro:IPR014727 Pfam:PF01028 Pfam:PF02919 PRINTS:PR00416 SMART:SM00435 MGI:MGI:1920210 GO:GO:0005524 GO:GO:0005694 GO:GO:0003677 GO:GO:0006260 GO:GO:0006200 EMBL:CH466545 GO:GO:0042645 GO:GO:0006265 SUPFAM:SSF56349 GO:GO:0003918 GO:GO:0003917 CTD:116447 eggNOG:COG3569 HOGENOM:HOG000105469 KO:K03163 OMA:VINCSRD OrthoDB:EOG7CVPX5 TreeFam:TF105281 Gene3D:1.10.10.41 Gene3D:1.10.132.10 Gene3D:2.170.11.10 Gene3D:3.90.15.10 InterPro:IPR025834 Pfam:PF14370 SUPFAM:SSF56741 EMBL:AF362952 EMBL:AK147119 EMBL:BC138582 EMBL:BC138583 RefSeq:NP_082680.1 UniGene:Mm.182401 ProteinModelPortal:Q8R4U6 SMR:Q8R4U6 PhosphoSite:Q8R4U6 PaxDb:Q8R4U6 PRIDE:Q8R4U6 Ensembl:ENSMUST00000000958 GeneID:72960 KEGG:mmu:72960 UCSC:uc007whb.1 GeneTree:ENSGT00390000016347 InParanoid:Q8R4U6 NextBio:337229 PRO:PR:Q8R4U6 ArrayExpress:Q8R4U6 Bgee:Q8R4U6 Genevestigator:Q8R4U6 Uniprot:Q8R4U6)

HSP 1 Score: 545.814 bits (1405), Expect = 0.000e+0
Identity = 284/560 (50.71%), Postives = 367/560 (65.54%), Query Frame = 0

Query:  355 WEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYSK----------------------------------SNQIRHVKSFLKI------KRGKG-----YYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            WEE       KW+ L+H+GP F P Y+ LP GVHF Y+ K +KLS   EEVA FY + +  E T KEVF RNFF DWRK MT EER +IT+L KCDF EI+ ++ + +E R+   +E+K+  KE+   +Q EFG CV+D H EKIGNF+ EPPGLFRGR     +G + R+                                     +  + H+++  K        + KG      YE AR LK  ++KIR  Y  D+KS EM+ RQ +VALYFIDKLALR GNEK+E + ADTVGCCSLRVEHI LH    G+++ VE DFLGKDSIRY N V VEK VF+N+Q FME+K   DDLFD L T+ LN++L  LM+GLTAKVFRT+NAS TLQ+QL  LT A+D+V  K+L+YNRANR VA+LCNHQRA PKT +KSMQ LQ KI+ K+    +A+ +L++A+   +  G +  K  + K+++ L +  EQL +L  +A DKEENK +ALGT+KLNYLDPRIS+AW K+F VP+EK+YNKTQR++F WA   AG D+ F
Sbjct:   36 WEETS-KSSVKWRQLEHKGPYFTPAYEPLPDGVHFLYDGKPLKLSLAAEEVATFYGKMLHLECTSKEVFRRNFFSDWRKEMTPEERRLITHLDKCDFTEIHKHFLERAEARRTLPREQKQKLKEEAEKLQQEFGYCVLDGHREKIGNFKTEPPGLFRGRGDHPKMGMLKRRVMPEDVVINCSRDSKIPEPPAGHQWKEVRSDNTVMWLAAWVEHIQNSFKYVILNPSSKPKGEMDWQKYEVARRLKGVVDKIRAQYQADWKSPEMKKRQLAVALYFIDKLALRTGNEKEEGETADTVGCCSLRVEHIRLHAPAGGQEHVVELDFLGKDSIRYKNHVTVEKLVFQNLQHFMEDKDPRDDLFDALTTSSLNKHLQDLMEGLTAKVFRTYNASVTLQEQLRVLTRAEDSVTCKVLAYNRANRAVAVLCNHQRAVPKTFEKSMQTLQKKIETKKAQVAEAQVELQKAETDLRMRGDSKPKSFLQKQRRLL-KLEEQLARLCAKATDKEENKQVALGTAKLNYLDPRISIAWCKRFGVPVEKIYNKTQRERFAWAFNQAGEDFEF 593          

BLAST of EMLSAG00000000293 vs. GO
Match: - (symbol:top-1 species:6239 "Caenorhabditis elegans" [GO:0018996 "molting cycle, collagen and cuticulin-based cuticle" evidence=IMP] [GO:0045132 "meiotic chromosome segregation" evidence=IMP] [GO:0002119 "nematode larval development" evidence=IMP] [GO:0010171 "body morphogenesis" evidence=IMP] [GO:0040011 "locomotion" evidence=IMP] [GO:0000003 "reproduction" evidence=IMP] [GO:0009792 "embryo development ending in birth or egg hatching" evidence=IMP] [GO:0048477 "oogenesis" evidence=IMP] [GO:0008406 "gonad development" evidence=IMP] [GO:0009790 "embryo development" evidence=IMP] [GO:0008340 "determination of adult lifespan" evidence=IMP] [GO:0006898 "receptor-mediated endocytosis" evidence=IMP] InterPro:IPR001631 InterPro:IPR008336 InterPro:IPR011010 InterPro:IPR013030 InterPro:IPR013034 InterPro:IPR013499 InterPro:IPR013500 InterPro:IPR014711 InterPro:IPR014727 InterPro:IPR018521 Pfam:PF01028 Pfam:PF02919 PRINTS:PR00416 PROSITE:PS00176 SMART:SM00435 GO:GO:0005524 GO:GO:0005730 GO:GO:0003677 GO:GO:0006260 GO:GO:0006200 GO:GO:0006338 GO:GO:0031616 GO:GO:0031298 GO:GO:0006265 SUPFAM:SSF56349 GO:GO:0003918 GO:GO:0003917 eggNOG:COG3569 HOGENOM:HOG000105469 KO:K03163 OrthoDB:EOG7CVPX5 Gene3D:1.10.10.41 Gene3D:1.10.132.10 Gene3D:2.170.11.10 Gene3D:3.90.15.10 InterPro:IPR025834 Pfam:PF14370 SUPFAM:SSF56741 GeneTree:ENSGT00390000016347 EMBL:X96762 EMBL:Z93385 PIR:S65469 PIR:T23647 PIR:T23648 RefSeq:NP_001021578.1 RefSeq:NP_493337.1 UniGene:Cel.17282 ProteinModelPortal:O17966 SMR:O17966 STRING:6239.M01E5.5a PaxDb:O17966 PRIDE:O17966 EnsemblMetazoa:M01E5.5a GeneID:266847 KEGG:cel:CELE_M01E5.5 UCSC:M01E5.5b CTD:266847 WormBase:M01E5.5a WormBase:M01E5.5b InParanoid:O17966 OMA:DEEHIHH NextBio:953260 Uniprot:O17966)

HSP 1 Score: 547.74 bits (1410), Expect = 1.804e-180
Identity = 313/575 (54.43%), Postives = 381/575 (66.26%), Query Frame = 0

Query:  350 EVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGRYL---VGFMDRKYS---------------------KSNQIRH----------VKSFL------------KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQA-DTVGCCSLRVEHITLHTV-------KDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGA---DYVF 865
            ++W+WW+EEK   G KW  LQH GPLFAP Y  LP  VHF Y  +KMKL+ ETEE+A FYA  ++HEY+ KE FN+NF KDWRKVMT EER+ I +L KCDFR I+ Y K+  E RK  +KEEK   KE+  A    +GI +ID H +K+ NFRIEPPG+FRGR     +G + ++                       K  ++RH           +S L            KIK  K +  YE AR LK KI  IR+ YT DFKSKEMRVRQR+ ALYFIDKLALRAGNEKD D+A DTVGCCSLRVEHI L          K  K++ VEFDFLGKDSIRY N V VEKRV+KN+++FME K   DDLFDRL+T  LN++L SLM GLT KVFRT+NAS TLQ+QL +LT   DNV AK+LSYNRANR+VAILCNHQRA  K  D+SMQ L+ KIK K++  ++AE  LK A+ A K           +K +K  +R  EQL KL+    DK+ENK IALGTSKLNY+DPRI+VAW KKF+VP+EKV+ KT R+KFRWAI+M  +   +YVF
Sbjct:  243 DIWEWWKEEKKPAGVKWNSLQHCGPLFAPPYIPLPSHVHFKYGGEKMKLTLETEEIAQFYAGVLDHEYSTKEAFNKNFMKDWRKVMTVEERERIHDLKKCDFRAIDAYQKEQREIRKAMTKEEKLKIKEEKEAEVKIYGIAIIDGHRQKVANFRIEPPGVFRGRGGHPKMGLIKKRIMPEDVIINCGKDTEIPKPPPGHKWKEVRHDNTVTWLCSWTESVLGQNKYIMLNPSSKIKGEKDFEKYETARRLKKKIGGIRERYTDDFKSKEMRVRQRATALYFIDKLALRAGNEKDVDEAADTVGCCSLRVEHIKLFDSAKLNEDDKKEKEFVVEFDFLGKDSIRYFNRVSVEKRVYKNLKIFMEGKAPSDDLFDRLDTATLNDHLRSLMDGLTVKVFRTYNASITLQEQLIKLTNPKDNVAAKILSYNRANRQVAILCNHQRAVSKGFDESMQKLEQKIKDKKKEVKEAEAALKSARGAEK-----------EKAQKKYDRLKEQLKKLKISRTDKDENKQIALGTSKLNYIDPRITVAWCKKFEVPLEKVFTKTHREKFRWAIDMTNSSDEEYVF 806          

BLAST of EMLSAG00000000293 vs. GO
Match: - (symbol:top-1 "DNA topoisomerase 1" species:6239 "Caenorhabditis elegans" [GO:0000166 "nucleotide binding" evidence=IEA] [GO:0003677 "DNA binding" evidence=IEA] [GO:0003916 "DNA topoisomerase activity" evidence=IEA] [GO:0003917 "DNA topoisomerase type I activity" evidence=IEA;IDA] [GO:0003918 "DNA topoisomerase type II (ATP-hydrolyzing) activity" evidence=IEA] [GO:0005524 "ATP binding" evidence=IEA] [GO:0005634 "nucleus" evidence=IEA;IDA] [GO:0005694 "chromosome" evidence=IEA] [GO:0005730 "nucleolus" evidence=IDA] [GO:0006200 "ATP catabolic process" evidence=IEA] [GO:0006260 "DNA replication" evidence=IBA] [GO:0006265 "DNA topological change" evidence=IEA;IBA] [GO:0006338 "chromatin remodeling" evidence=IBA] [GO:0016853 "isomerase activity" evidence=IEA] [GO:0031298 "replication fork protection complex" evidence=IBA] [GO:0031616 "spindle pole centrosome" evidence=IDA] InterPro:IPR001631 InterPro:IPR008336 InterPro:IPR011010 InterPro:IPR013030 InterPro:IPR013034 InterPro:IPR013499 InterPro:IPR013500 InterPro:IPR014711 InterPro:IPR014727 InterPro:IPR018521 Pfam:PF01028 Pfam:PF02919 PRINTS:PR00416 PROSITE:PS00176 SMART:SM00435 GO:GO:0005524 GO:GO:0005730 GO:GO:0003677 GO:GO:0006260 GO:GO:0006200 GO:GO:0006338 GO:GO:0031616 GO:GO:0031298 GO:GO:0006265 SUPFAM:SSF56349 GO:GO:0003918 GO:GO:0003917 eggNOG:COG3569 HOGENOM:HOG000105469 KO:K03163 OrthoDB:EOG7CVPX5 Gene3D:1.10.10.41 Gene3D:1.10.132.10 Gene3D:2.170.11.10 Gene3D:3.90.15.10 InterPro:IPR025834 Pfam:PF14370 SUPFAM:SSF56741 GeneTree:ENSGT00390000016347 EMBL:X96762 EMBL:Z93385 PIR:S65469 PIR:T23647 PIR:T23648 RefSeq:NP_001021578.1 RefSeq:NP_493337.1 UniGene:Cel.17282 ProteinModelPortal:O17966 SMR:O17966 STRING:6239.M01E5.5a PaxDb:O17966 PRIDE:O17966 EnsemblMetazoa:M01E5.5a GeneID:266847 KEGG:cel:CELE_M01E5.5 UCSC:M01E5.5b CTD:266847 WormBase:M01E5.5a WormBase:M01E5.5b InParanoid:O17966 OMA:DEEHIHH NextBio:953260 Uniprot:O17966)

HSP 1 Score: 547.74 bits (1410), Expect = 1.804e-180
Identity = 313/575 (54.43%), Postives = 381/575 (66.26%), Query Frame = 0

Query:  350 EVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGRYL---VGFMDRKYS---------------------KSNQIRH----------VKSFL------------KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQA-DTVGCCSLRVEHITLHTV-------KDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGA---DYVF 865
            ++W+WW+EEK   G KW  LQH GPLFAP Y  LP  VHF Y  +KMKL+ ETEE+A FYA  ++HEY+ KE FN+NF KDWRKVMT EER+ I +L KCDFR I+ Y K+  E RK  +KEEK   KE+  A    +GI +ID H +K+ NFRIEPPG+FRGR     +G + ++                       K  ++RH           +S L            KIK  K +  YE AR LK KI  IR+ YT DFKSKEMRVRQR+ ALYFIDKLALRAGNEKD D+A DTVGCCSLRVEHI L          K  K++ VEFDFLGKDSIRY N V VEKRV+KN+++FME K   DDLFDRL+T  LN++L SLM GLT KVFRT+NAS TLQ+QL +LT   DNV AK+LSYNRANR+VAILCNHQRA  K  D+SMQ L+ KIK K++  ++AE  LK A+ A K           +K +K  +R  EQL KL+    DK+ENK IALGTSKLNY+DPRI+VAW KKF+VP+EKV+ KT R+KFRWAI+M  +   +YVF
Sbjct:  243 DIWEWWKEEKKPAGVKWNSLQHCGPLFAPPYIPLPSHVHFKYGGEKMKLTLETEEIAQFYAGVLDHEYSTKEAFNKNFMKDWRKVMTVEERERIHDLKKCDFRAIDAYQKEQREIRKAMTKEEKLKIKEEKEAEVKIYGIAIIDGHRQKVANFRIEPPGVFRGRGGHPKMGLIKKRIMPEDVIINCGKDTEIPKPPPGHKWKEVRHDNTVTWLCSWTESVLGQNKYIMLNPSSKIKGEKDFEKYETARRLKKKIGGIRERYTDDFKSKEMRVRQRATALYFIDKLALRAGNEKDVDEAADTVGCCSLRVEHIKLFDSAKLNEDDKKEKEFVVEFDFLGKDSIRYFNRVSVEKRVYKNLKIFMEGKAPSDDLFDRLDTATLNDHLRSLMDGLTVKVFRTYNASITLQEQLIKLTNPKDNVAAKILSYNRANRQVAILCNHQRAVSKGFDESMQKLEQKIKDKKKEVKEAEAALKSARGAEK-----------EKAQKKYDRLKEQLKKLKISRTDKDENKQIALGTSKLNYIDPRITVAWCKKFEVPLEKVFTKTHREKFRWAIDMTNSSDEEYVF 806          

BLAST of EMLSAG00000000293 vs. C. finmarchicus
Match: gi|592776306|gb|GAXK01178262.1| (TSA: Calanus finmarchicus comp15061_c1_seq1 transcribed RNA sequence)

HSP 1 Score: 619.002 bits (1595), Expect = 0.000e+0
Identity = 359/548 (65.51%), Postives = 414/548 (75.55%), Query Frame = 0

Query:  363 GTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYXXXXXXXXXXXXXXXXXXXXXXXAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---------------------------YLVGFMDRKYSK-----------------SNQIRHV----KSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDXXXXXXXXXXXXXXXXXXXXXXYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGAD 862
            G KWKFLQH GP FAPDYD LP+ V F+Y  K ++L+ ETEE A FY R ++H+YT KEVFN+NFFKDWRKVMT +E+DII +LSKCDF EIN ++KKVSEERKNRSKEEKKAEKE N AI  +FG C +D H EKIGNFR EPP LFRGR                             V    RK+ K                   QI+++     S LK ++    YEKAR+LK +I KIRDDY  D KSKEMRVRQR+VALYFID+LALRAGNEKDEDQADTVGCCSLRVEHI LH   DGK++ VEFDFLGKDSIRYHN   VEK+V+KNV+LFMENK+  DDLFDRLNT++LN+YLNSLM GLTAKVFRT+NASFTLQ+QL+E+T+ +DNV AKMLSYNRANR VA+LCNHQRA PKTH+KSM NL  KI+AK++A ++AEK LK AKKAYKN GS +EK   +KKKK LER +EQL+KLE Q  DK+ENKTIALGTSKLNYLDPRISVAW KK DVPIEKVYNKTQR+KFRWAI+M   D
Sbjct: 1523 GVKWKFLQHLGPQFAPDYDPLPEHVRFWYEGKTLRLTEETEECATFYGRMLDHDYTTKEVFNKNFFKDWRKVMTEKEKDIIRDLSKCDFSEINEHFKKVSEERKNRSKEEKKAEKEVNEAIIADFGFCTMDGHQEKIGNFRTEPPSLFRGRGEHPKQGMIKRRIMPEDVIINCSKDSEIPVPPKGRKWKKVQHDNTVTWLASWTENIQGQIKYIMLNPSSRLKGEKDWQKYEKARKLKVEIHKIRDDYMEDMKSKEMRVRQRAVALYFIDRLALRAGNEKDEDQADTVGCCSLRVEHIELHEQLDGKEFVVEFDFLGKDSIRYHNTTSVEKKVYKNVKLFMENKKDGDDLFDRLNTSVLNQYLNSLMDGLTAKVFRTYNASFTLQEQLDEMTDPNDNVSAKMLSYNRANRAVAVLCNHQRAVPKTHEKSMDNLYGKIEAKQDAIKEAEKGLKHAKKAYKNNGSVAEKANAEKKKKTLERLLEQLEKLEIQKTDKDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKVYNKTQREKFRWAIDMITND 3166          

BLAST of EMLSAG00000000293 vs. C. finmarchicus
Match: gi|592810838|gb|GAXK01143730.1| (TSA: Calanus finmarchicus comp3642341_c0_seq1 transcribed RNA sequence)

HSP 1 Score: 35.8094 bits (81), Expect = 5.175e-1
Identity = 23/51 (45.10%), Postives = 37/51 (72.55%), Query Frame = 0

Query:  778 TSEKVVMDKKKKALERTVEQL-DKLETQAVDKEENKTIALGTSKLNYLDPR 827
            ++EK +M++K K LE   E L +KLET+ ++KEE+K+++    +LN LDPR
Sbjct:  560 SNEKEIMEEKLKDLETENEILREKLETKEIEKEESKSLS---EELNILDPR 703          

BLAST of EMLSAG00000000293 vs. C. finmarchicus
Match: gi|592938100|gb|GAXK01020453.1| (TSA: Calanus finmarchicus comp12086_c0_seq4 transcribed RNA sequence)

HSP 1 Score: 35.039 bits (79), Expect = 1.346e+0
Identity = 24/87 (27.59%), Postives = 44/87 (50.57%), Query Frame = 0

Query:  780 EKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVA---WSKKFDVPIEKVYNKTQRDKFRWAIEMAGADY 863
            E+  +++++  L +  E+  +LETQ  +   N   A G+S    ++PRI  +   W  +  V    ++ ++QR   R   EMAG D+
Sbjct: 2196 ERSELERREAILAKNREREGRLETQRKNSRGNIEFAFGSSAPRLIEPRIDSSSGYWGSR-SVTGPGMFERSQRSMDR---EMAGGDF 2444          

BLAST of EMLSAG00000000293 vs. C. finmarchicus
Match: gi|592938102|gb|GAXK01020451.1| (TSA: Calanus finmarchicus comp12086_c0_seq2 transcribed RNA sequence)

HSP 1 Score: 35.039 bits (79), Expect = 1.361e+0
Identity = 24/87 (27.59%), Postives = 44/87 (50.57%), Query Frame = 0

Query:  780 EKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVA---WSKKFDVPIEKVYNKTQRDKFRWAIEMAGADY 863
            E+  +++++  L +  E+  +LETQ  +   N   A G+S    ++PRI  +   W  +  V    ++ ++QR   R   EMAG D+
Sbjct: 2615 ERSELERREAILAKNREREGRLETQRKNSRGNIEFAFGSSAPRLIEPRIDSSSGYWGSR-SVTGPGMFERSQRSMDR---EMAGGDF 2863          

BLAST of EMLSAG00000000293 vs. C. finmarchicus
Match: gi|592938101|gb|GAXK01020452.1| (TSA: Calanus finmarchicus comp12086_c0_seq3 transcribed RNA sequence)

HSP 1 Score: 33.113 bits (74), Expect = 5.935e+0
Identity = 23/92 (25.00%), Postives = 43/92 (46.74%), Query Frame = 0

Query:  780 EKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVA---WSKKFDVPIEKVYNKT-----QRDKFRWAIEMAGADY 863
            E+  +++++  L +  E+  +LETQ  +   N   A G+S    ++PRI  +   W  +       V++ T     +R +     EMAG D+
Sbjct: 2196 ERSELERREAILAKNREREGRLETQRKNSRGNIEFAFGSSAPRLIEPRIDSSSGYWGSRRATSSTNVHSVTGPGMFERSQRSMDREMAGGDF 2471          

BLAST of EMLSAG00000000293 vs. C. finmarchicus
Match: gi|592938103|gb|GAXK01020450.1| (TSA: Calanus finmarchicus comp12086_c0_seq1 transcribed RNA sequence)

HSP 1 Score: 33.113 bits (74), Expect = 5.996e+0
Identity = 23/92 (25.00%), Postives = 43/92 (46.74%), Query Frame = 0

Query:  780 EKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVA---WSKKFDVPIEKVYNKT-----QRDKFRWAIEMAGADY 863
            E+  +++++  L +  E+  +LETQ  +   N   A G+S    ++PRI  +   W  +       V++ T     +R +     EMAG D+
Sbjct: 2615 ERSELERREAILAKNREREGRLETQRKNSRGNIEFAFGSSAPRLIEPRIDSSSGYWGSRRATSSTNVHSVTGPGMFERSQRSMDREMAGGDF 2890          

BLAST of EMLSAG00000000293 vs. C. finmarchicus
Match: gi|592912910|gb|GAXK01045465.1| (TSA: Calanus finmarchicus comp416754_c0_seq1 transcribed RNA sequence)

HSP 1 Score: 31.9574 bits (71), Expect = 7.930e+0
Identity = 15/45 (33.33%), Postives = 25/45 (55.56%), Query Frame = 0

Query:  773 KNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALG 817
            K  G  +E ++MDK KKA+E+T +  +KL    + +     + LG
Sbjct:  617 KTAGERNEALMMDKAKKAMEKTTDPGEKLRCYCLSRGATGILGLG 751          

BLAST of EMLSAG00000000293 vs. L. salmonis peptides
Match: EMLSAP00000000293 (pep:novel supercontig:LSalAtl2s:LSalAtl2s1044:15439:19815:-1 gene:EMLSAG00000000293 transcript:EMLSAT00000000293 description:"maker-LSalAtl2s1044-snap-gene-0.46")

HSP 1 Score: 1739.93 bits (4505), Expect = 0.000e+0
Identity = 865/865 (100.00%), Postives = 865/865 (100.00%), Query Frame = 0

Query:    1 MGENGTMLHHGSSGLNGEAFTNGSTETKASDHRHSSSKHKHKDKERRKETEEERRVRKEQERKEREDRHKREGRREETEEERRARKEKERREREERHKREGRRDETEEERKVRKEKERKEREERHKREGRRDETEDERRLRKERERKEREERHKREGRREETEEERKARKEKEQRHKSKETEEERRVRKDKERAEKEARKRKEMGYDHSMGEEVSFHNHDEEMKMEQQEQQVKDEPQYEEELHEEQDEFEEDRYNNAKQENMEVEVKVQDDSEDDIPLAKKSKNKKRKSRDEDSEDDVPLSKRKKPKVKKVERVEVSKKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGRYLVGFMDRKYSKSNQIRHVKSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            MGENGTMLHHGSSGLNGEAFTNGSTETKASDHRHSSSKHKHKDKERRKETEEERRVRKEQERKEREDRHKREGRREETEEERRARKEKERREREERHKREGRRDETEEERKVRKEKERKEREERHKREGRRDETEDERRLRKERERKEREERHKREGRREETEEERKARKEKEQRHKSKETEEERRVRKDKERAEKEARKRKEMGYDHSMGEEVSFHNHDEEMKMEQQEQQVKDEPQYEEELHEEQDEFEEDRYNNAKQENMEVEVKVQDDSEDDIPLAKKSKNKKRKSRDEDSEDDVPLSKRKKPKVKKVERVEVSKKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGRYLVGFMDRKYSKSNQIRHVKSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF
Sbjct:    1 MGENGTMLHHGSSGLNGEAFTNGSTETKASDHRHSSSKHKHKDKERRKETEEERRVRKEQERKEREDRHKREGRREETEEERRARKEKERREREERHKREGRRDETEEERKVRKEKERKEREERHKREGRRDETEDERRLRKERERKEREERHKREGRREETEEERKARKEKEQRHKSKETEEERRVRKDKERAEKEARKRKEMGYDHSMGEEVSFHNHDEEMKMEQQEQQVKDEPQYEEELHEEQDEFEEDRYNNAKQENMEVEVKVQDDSEDDIPLAKKSKNKKRKSRDEDSEDDVPLSKRKKPKVKKVERVEVSKKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGRYLVGFMDRKYSKSNQIRHVKSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865          

BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|12644118|sp|P11387.2|TOP1_HUMAN (RecName: Full=DNA topoisomerase 1; AltName: Full=DNA topoisomerase I)

HSP 1 Score: 639.032 bits (1647), Expect = 0.000e+0
Identity = 330/553 (59.67%), Postives = 401/553 (72.51%), Query Frame = 0

Query:  362 DGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            +G KWKFL+H+GP+FAP Y+ LP+ V FYY+ K MKLS + EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT EE++IITNLSKCDF +++ Y+K  +E RK  SKEEK   KE+N  +  E+G C++DNH E+I NF+IEPPGLFRGR     +G + R+                       K  ++RH                 +K  +     +IK  K +  YE AR LK  ++KIR+ Y  D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI LH   DG++Y VEFDFLGKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT ILN++L  LM+GLTAKVFRT+NAS TLQ QL+ELT  D+N+PAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK+E    A +DLK AK   K       K V++ KKKA++R  EQL KLE QA D+EENK IALGTSKLNYLDPRI+VAW KK+ VPIEK+YNKTQR+KF WAI+MA  DY F
Sbjct:  213 EGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTKIDAKKEQLADARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF 765          

BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|38503303|sp|Q7YR26.1|TOP1_CHLAE (RecName: Full=DNA topoisomerase 1; AltName: Full=DNA topoisomerase I)

HSP 1 Score: 638.262 bits (1645), Expect = 0.000e+0
Identity = 330/552 (59.78%), Postives = 399/552 (72.28%), Query Frame = 0

Query:  363 GTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            G KWKFL+H+GP+FAP Y+ LP  V FYY+ K MKLS + EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT EE++IITNLSKCDF +++ Y+K  +E RK  SKEEK   KE+N  +  E+G C++DNH E+I NF+IEPPGLFRGR     +G + R+                       K  ++RH                 +K  +     +IK  K +  YE AR LK  ++KIR+ Y  D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI LH   DG++Y VEFDFLGKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT ILN++L  LM+GLTAKVFRT+NAS TLQ QL+ELT  D+N+PAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK+E    A +DLK AK   K       K V++ KKKA++R  EQL KLE QA D+EENK IALGTSKLNYLDPRI+VAW KK+ VPIEK+YNKTQR+KF WAI+MA  DY F
Sbjct:  216 GIKWKFLEHKGPVFAPPYEPLPDSVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKEQLADARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF 767          

BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|51316560|sp|Q9WUL0.1|TOP1_RAT (RecName: Full=DNA topoisomerase 1; AltName: Full=DNA topoisomerase I)

HSP 1 Score: 634.795 bits (1636), Expect = 0.000e+0
Identity = 330/552 (59.78%), Postives = 398/552 (72.10%), Query Frame = 0

Query:  363 GTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            G KWKFL+H+GP+FAP Y+ LP+GV FYY+ K MKLS + EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT +E++ ITNLSKCDF +++ Y+K  SE RK  SKEEK   KE+N  +  E+G CV+DNH E+I NF+IEPPGLFRGR     +G + R+                       K  ++RH                 +K  +     +IK  K +  YE AR LK  ++KIR+ Y  D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI LH   DG++Y VEFDF GKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT ILN++L  LM+GLTAKVFRT+NAS TLQ QL+ELT  D+NVPAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK++    A KDLK AK   K       K V++ KKKA++R  EQL KLE QA D+EENK IALGTSKLNYLDPRI+VAW KK+ VPIEK+YNKTQR+KF WAI+M   DY F
Sbjct:  216 GIKWKFLEHKGPVFAPPYEPLPEGVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNDEKNTITNLSKCDFTQMSQYFKAQSEARKQMSKEEKLKIKEENEKLLKEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARKDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 767          

BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|586107|sp|Q07050.1|TOP1_CRIGR (RecName: Full=DNA topoisomerase 1; AltName: Full=DNA topoisomerase I)

HSP 1 Score: 632.484 bits (1630), Expect = 0.000e+0
Identity = 328/552 (59.42%), Postives = 398/552 (72.10%), Query Frame = 0

Query:  363 GTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            G KWKFL+H+GP+FAP Y+ LP+GV FYY+ K MKLS + EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT +E+++ITNLSKCDF +++ Y+K  SE RK  SKEEK   KE+N  +  E+G CV+DNH E+I NF+IEPPGLFRGR     +G + R+                       K  ++RH                 +K  +     +IK  K +  YE AR LK  ++KIR+ Y  D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTV CCSLRVEHI LH   DG++Y VEFDF GKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT ILN++L  LM+GLTAKVFRT+NAS TLQ QL+ELT  D+NVPAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK++    A +DLK AK   K       K V++ KKKA++R  EQL KLE QA D+EENK IALGTSKLNYLDPRI+VAW KK+ VPIEK+YNKTQR+KF WAI+M   DY F
Sbjct:  216 GIKWKFLEHKGPVFAPPYEPLPEGVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNDEKNVITNLSKCDFTQMSQYFKDQSEARKQMSKEEKLKIKEENEKLLKEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVSCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 767          

BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|158518540|sp|Q04750.2|TOP1_MOUSE (RecName: Full=DNA topoisomerase 1; AltName: Full=DNA topoisomerase I)

HSP 1 Score: 631.713 bits (1628), Expect = 0.000e+0
Identity = 328/552 (59.42%), Postives = 397/552 (71.92%), Query Frame = 0

Query:  363 GTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            G KWKFL+H+GP+FAP Y+ LP+ V FYY+ K MKLS + EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT +E++ ITNLSKCDF +++ Y+K  SE RK  SKEEK   KE+N  +  E+G CV+DNH E+I NF+IEPPGLFRGR     +G + R+                       K  ++RH                 +K  +     +IK  K +  YE AR LK  ++KIR+ Y  D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI LH   DG++Y VEFDF GKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT ILN++L  LM+GLTAKVFRT+NAS TLQ QL+ELT  D+NVPAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK++    A +DLK AK   K       K V++ KKKA++R  EQL KLE QA D+EENK IALGTSKLNYLDPRI+VAW KK+ VPIEK+YNKTQR+KF WAI+M   DY F
Sbjct:  216 GIKWKFLEHKGPVFAPPYEPLPESVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNDEKNTITNLSKCDFTQMSQYFKAQSEARKQMSKEEKLKIKEENEKLLKEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 767          

BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|1174739|sp|P41512.1|TOP1_XENLA (RecName: Full=DNA topoisomerase 1; AltName: Full=DNA topoisomerase I)

HSP 1 Score: 609.372 bits (1570), Expect = 0.000e+0
Identity = 312/537 (58.10%), Postives = 385/537 (71.69%), Query Frame = 0

Query:  362 DGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRG------------RYLVGFMDRKYSKSNQI------------RH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQR 849
            DG KWKFL+H+GP+FAP Y+ +P  V FYY+   +KLS + EEVA F+A+ ++HEYT K++F +NFFKDW+K MT +ER++ITNLSKCDF  ++ Y+K+ SE RKN +KEEK   K +N  +  E+G C++DNH E+I NFRIEPPGLFRG            R +   +    SK ++I            RH                 +K  +     +IK  K +  YE AR LK  +EKIR+ Y  D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI L    DG+++ VEFDF GKDSIRY+N VPVEKRVFKN+QLFMENK+ +DDLFDRLNT+ILN++L  LM+GLTAKVFRT+NAS TLQ QL+ELT +DDNVPAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK++    A ++ K AK   K       K +++ KKKA++R  EQL KLE QA D+EENK IALGTSKLNYLDPRISVAW KK+ VPIEK+YNKTQR
Sbjct:  269 DGIKWKFLEHKGPVFAPPYEPVPDNVKFYYDGNLVKLSPKAEEVATFFAKMLDHEYTTKDIFRKNFFKDWKKEMTTDERNLITNLSKCDFNAMSLYFKEQSEARKNMTKEEKLKIKAENERLLQEYGYCIMDNHKERIANFRIEPPGLFRGRGDHPKMGKLKKRIMPEDIIINCSKDSKIPVAPAGHKWKEVRHDGKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKMCVEKIRNTYKEDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLFQELDGQEFVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMENKQPDDDLFDRLNTSILNKHLQDLMEGLTAKVFRTYNASITLQQQLDELTNSDDNVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQGKIDAKKDQLADARREFKSAKADAKVRRDEKTKKLVESKKKAVQRIEEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKYGVPIEKIYNKTQR 805          

BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|20140694|sp|Q969P6.1|TOP1M_HUMAN (RecName: Full=DNA topoisomerase I, mitochondrial; Short=TOP1mt; Flags: Precursor)

HSP 1 Score: 598.201 bits (1541), Expect = 0.000e+0
Identity = 303/560 (54.11%), Postives = 385/560 (68.75%), Query Frame = 0

Query:  355 WEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKY-----------------------------------------SKSNQIRHVK----SFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEK-DEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            WE+EK +DG KW+ L+H+GP FAP Y+ LP GV F+Y  + ++LS   EEVA FY R ++HEYT KEVF +NFF DWRK M  EER++I +L KCDF EI+ Y+   +  RK  S+EEK+  KE+   +Q EFG C++D H EKIGNF+IEPPGLFRGR     +G + R+                                          S  N I+++     S LK +     +E AR L+  +++IR  Y  D+KS+EM+ RQR+VALYFIDKLALRAGNEK D + ADTVGCCSLRVEH+ LH   DG  + VEFDFLGKD IRY+N VPVEK V+KN+QLFMENK   DDLFDRL TT LN++L  LM GLTAKVFRT+NAS TLQ+QL  LT A+D++ AK+LSYNRANR VAILCNHQRA P T +KSMQNLQ KI+AK+E   +A  +L++A+  +K  G    + V++KK++ LE+  EQL +L  QA DKEENK +ALGTSKLNYLDPRIS+AW K+F VP+EK+Y+KTQR++F WA+ MAG D+ F
Sbjct:   42 WEKEKHEDGVKWRQLEHKGPYFAPPYEPLPDGVRFFYEGRPVRLSVAAEEVATFYGRMLDHEYTTKEVFRKNFFNDWRKEMAVEEREVIKSLDKCDFTEIHRYFVDKAAARKVLSREEKQKLKEEAEKLQQEFGYCILDGHQEKIGNFKIEPPGLFRGRGDHPKMGMLKRRITPEDVVINCSRDSKIPEPPAGHQWKEVRSDNTVTWLAAWTESVQNSIKYIMLNPCSKLKGETAWQKFETARRLRGFVDEIRSQYRADWKSREMKTRQRAVALYFIDKLALRAGNEKEDGEAADTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCIRYYNRVPVEKPVYKNLQLFMENKDPRDDLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEARAELRRARAEHKAQGDGKSRSVLEKKRRLLEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKIYSKTQRERFAWALAMAGEDFEF 601          

BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|267147|sp|P30189.1|TOP1_DROME (RecName: Full=DNA topoisomerase 1; AltName: Full=DNA topoisomerase I)

HSP 1 Score: 595.504 bits (1534), Expect = 0.000e+0
Identity = 311/552 (56.34%), Postives = 383/552 (69.38%), Query Frame = 0

Query:  362 DGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYSKSN---------------------QIRH------VKSFLKIKRG-------------KG-----YYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            DG KW  L+H+GP+FAP Y+R+P+ V FYY+ K ++LS ETEE A FYA+ + H+Y  KEVFN NFFKD+RK MT  ER+II +  KC+F+E+  Y++  SE+RK  SKEEK  +K +N A+  EFG C+ID H EKIGNFR+EPPGLFRGR     +G + R+   S+                     ++RH      + S+++  +G             KG      YE AR L   I+KIR  Y  ++KSKEMRVRQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEH+ LH   +GK+  V FDF GKDSIRY+N V VEKRVFKN++LFME+K+  DDLFDRLNT +LNE+L  LM+GLTAKVFRT+NAS TLQ QL+ LT+    VP K+L+YNRANR VAILCNHQR+ PK+H+KSM+NL++KIKAKREA EK E +                    +KK K LER  +QL KLE Q  D++ENKTIALGTSKLNYLDPRISVAW KK DVPIEK++NKTQR KF WA+ MA  +Y F
Sbjct:  436 DGVKWSTLEHKGPVFAPRYERVPRNVRFYYDGKPLELSEETEEAATFYAKMLNHDYCTKEVFNNNFFKDFRKSMTPREREIIKDFRKCNFQEMFNYFQAESEKRKAASKEEKLIKKNENEALMKEFGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIQASDVSINCGKDSKVPSPPPGSRWKEVRHDNTVTWLASWIENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLELFMEHKKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEKIKAKREAIEKCESEYHSRD---------------EKKGKQLERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQRTKFLWAVHMADENYRF 972          

BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|259533973|sp|A9Q1D5.1|TOP1M_PANTR (RecName: Full=DNA topoisomerase I, mitochondrial; Short=TOP1mt; Flags: Precursor)

HSP 1 Score: 593.578 bits (1529), Expect = 0.000e+0
Identity = 302/560 (53.93%), Postives = 384/560 (68.57%), Query Frame = 0

Query:  355 WEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKY-----------------------------------------SKSNQIRHVK----SFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEK-DEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            WE+EK +DG KW+ L+H+GP FAP Y+ LP GV F+Y  K ++LS   EEVA FY R + HEYT KEVF +NFF DWRK M  EER++I +L KCDF EI+ Y+   +  RK  S+EEK+  KE+   +Q EFG C++D H EKIGNF+IEPPGLFRGR     +G + R+                                          S  N I+++     S LK +     +E AR L+  +++IR  Y  D+KS+EM+ RQR+VALYFIDKLALRAGNEK D + ADTVGCCSLRVEH+ LH   DG  + VEFDFLGKD IRY+N VPVEK V+KN+QLFME+K   D+LFDRL TT LN++L  LM GLTAKVFRT+NAS TLQ+QL  LT A+D++ AK+LSYNRANR VAILCNHQRA P T +KSMQNLQ KI+AK+E   +A  +L++A+  +K  G    + V++KK++ LE+  EQL +L  QA DKEENK +ALGTSKLNYLDPRIS+AW K+F VP+EK+Y+KTQR++F WA+ MAG D+ F
Sbjct:   42 WEKEKHEDGVKWRQLEHKGPYFAPPYEPLPDGVRFFYEGKPVRLSVAAEEVATFYGRMLGHEYTTKEVFRKNFFNDWRKEMAVEEREVIKSLDKCDFTEIHRYFVDKAAARKVLSREEKQKLKEEAEKLQREFGYCILDGHQEKIGNFKIEPPGLFRGRGDHPKMGMLKRRIMPEDVVINCSRDSKIPEPPAGHQWKEVRSDNTVTWLAAWTESVQNSIKYIMLNPCSKLKGETAWQKFETARRLRGFVDEIRSQYRADWKSREMKTRQRAVALYFIDKLALRAGNEKEDGEAADTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCIRYYNRVPVEKPVYKNLQLFMESKGPRDNLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEARAELRRARAEHKAQGDGKSRSVLEKKRRLLEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKIYSKTQRERFAWALAMAGEDFEF 601          

BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|74957937|sp|O17966.1|TOP1_CAEEL (RecName: Full=DNA topoisomerase 1; AltName: Full=DNA topoisomerase I; Short=topoI)

HSP 1 Score: 547.74 bits (1410), Expect = 0.000e+0
Identity = 313/575 (54.43%), Postives = 381/575 (66.26%), Query Frame = 0

Query:  350 EVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGRYL---VGFMDRKYS---------------------KSNQIRH----------VKSFL------------KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQA-DTVGCCSLRVEHITLHTV-------KDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGA---DYVF 865
            ++W+WW+EEK   G KW  LQH GPLFAP Y  LP  VHF Y  +KMKL+ ETEE+A FYA  ++HEY+ KE FN+NF KDWRKVMT EER+ I +L KCDFR I+ Y K+  E RK  +KEEK   KE+  A    +GI +ID H +K+ NFRIEPPG+FRGR     +G + ++                       K  ++RH           +S L            KIK  K +  YE AR LK KI  IR+ YT DFKSKEMRVRQR+ ALYFIDKLALRAGNEKD D+A DTVGCCSLRVEHI L          K  K++ VEFDFLGKDSIRY N V VEKRV+KN+++FME K   DDLFDRL+T  LN++L SLM GLT KVFRT+NAS TLQ+QL +LT   DNV AK+LSYNRANR+VAILCNHQRA  K  D+SMQ L+ KIK K++  ++AE  LK A+ A K           +K +K  +R  EQL KL+    DK+ENK IALGTSKLNY+DPRI+VAW KKF+VP+EKV+ KT R+KFRWAI+M  +   +YVF
Sbjct:  243 DIWEWWKEEKKPAGVKWNSLQHCGPLFAPPYIPLPSHVHFKYGGEKMKLTLETEEIAQFYAGVLDHEYSTKEAFNKNFMKDWRKVMTVEERERIHDLKKCDFRAIDAYQKEQREIRKAMTKEEKLKIKEEKEAEVKIYGIAIIDGHRQKVANFRIEPPGVFRGRGGHPKMGLIKKRIMPEDVIINCGKDTEIPKPPPGHKWKEVRHDNTVTWLCSWTESVLGQNKYIMLNPSSKIKGEKDFEKYETARRLKKKIGGIRERYTDDFKSKEMRVRQRATALYFIDKLALRAGNEKDVDEAADTVGCCSLRVEHIKLFDSAKLNEDDKKEKEFVVEFDFLGKDSIRYFNRVSVEKRVYKNLKIFMEGKAPSDDLFDRLDTATLNDHLRSLMDGLTVKVFRTYNASITLQEQLIKLTNPKDNVAAKILSYNRANRQVAILCNHQRAVSKGFDESMQKLEQKIKDKKKEVKEAEAALKSARGAEK-----------EKAQKKYDRLKEQLKKLKISRTDKDENKQIALGTSKLNYIDPRITVAWCKKFEVPLEKVFTKTHREKFRWAIDMTNSSDEEYVF 806          

BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: gb|EFA03005.1| (DNA topoisomerase 1-like Protein [Tribolium castaneum])

HSP 1 Score: 715.301 bits (1845), Expect = 0.000e+0
Identity = 382/672 (56.85%), Postives = 481/672 (71.58%), Query Frame = 0

Query:  260 ENMEVEVKVQDDSEDDIPLAKKSKNKKRKSRDE-DSEDDVPLSKRKKPKVKKVERVEVSKKSKSSKKNH-----------------KVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKY-----------------------------------------SKSNQIRHV----KSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            E+   +VK ++DS++D+PL+ + ++   K + E D EDD+PL+ RKKPK +K E+ E  KK +S + +                   +K E  SP K G +KK+E+  EVWKWWEEEK DDG KWKFL+H+GP+FAP Y+ LP  V FYY+ K+MKL+ E EEVA FY++ ++H+YT KEVFN NFFKDWRKVM+  ER +I +L KC+F+ ++ YY  ++E+ +NR+KEEK+A KEKN A+  E+G C ID H EKIGNF+IEPPGLFRGR     +G + R+                                          +  NQ++++     S LK ++    YE AR L   I+KIR++Y  D+KSKEMR+RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHI+LH  KDGK+Y V FDFLGKDSIRY+N VPVEKRVFKN+QLFME+K   DDLFDRLNT I+N++LN LM+GLTAKVFRT+NAS+TLQ QL++LT ADD+V  K+L+YNRANR VAILCNHQR+ PK H+KSM+ L++KI AK+EA + AE+ +K A K  K+ GS  EK V DKKKK L+R  EQL KLE Q  D++ENKTIALGTSKLNYLDPRISVAW KK+ VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct:  273 EDSTADVKQEEDSDEDLPLSARMEHTSVKRKIESDDEDDMPLNARKKPKKEKKEKSEKKKKKRSVEDDEEEWDRPVKKEKIKKEKDSIKTENESPKKGGRKKKEEEPQEVWKWWEEEKKDDGKKWKFLEHKGPVFAPPYEPLPDHVKFYYDGKEMKLTPEAEEVASFYSKMLDHDYTTKEVFNNNFFKDWRKVMSESERKVIKDLKKCNFKSMHAYYMDLAEKNRNRTKEEKQALKEKNEALIKEYGFCNIDGHKEKIGNFKIEPPGLFRGRGEHPKMGMLKRRVEAEDIIINCSQDSKIPEPPPGHKWKEVRHDDNVTWLASWTENVQNQVKYIMLNPSSKLKGEKDWQKYETARRLHKCIDKIREEYKDDWKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHISLHKEKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMEHKSPGDDLFDRLNTAIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTNADDSVAEKILAYNRANRAVAILCNHQRSVPKGHEKSMEKLKEKIDAKKEAIKDAERQVKDAAKDAKH-GSVKEKTVYDKKKKMLQRLKEQLTKLEIQETDRDENKTIALGTSKLNYLDPRISVAWCKKYGVPIEKIYNKTQRDKFRWAIDMAGPDYVF 943          

BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: XP_396203.4 (PREDICTED: DNA topoisomerase I, mitochondrial isoform X1 [Apis mellifera])

HSP 1 Score: 711.064 bits (1834), Expect = 0.000e+0
Identity = 383/661 (57.94%), Postives = 470/661 (71.10%), Query Frame = 0

Query:  266 VKVQDDSEDDIPLAKKS--KNKKRKSRDEDSEDDVPLSKRKKPKVKKVERVEVSKKSKSSKKNHKVKHEVVSPTKSGGR-----------KKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR-----------------YLVGFM-DRKYSKSN------QIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            +K +++S++D+PL+ +S      ++S D + E+DVPLS RKK K    +  +  +K +  +   +++ +   P K G R           KK+E++ EVWKWWEEEK +DGTKW FL+H+GP+FAP Y+ LP  V+FYYN K+MKLS +TEEVA FYAR ++H+YT K  FN NFF DWR+VMT  ER  I +LSKC+F+EI+ Y+ + SEERK  +KEEK+  KEKN  IQ E+G C+ID H EKIGNF+IEPPGLFRGR                  L+    D    K        +IRH                 VK  +     K+K  K +  YE AR+L   I+KIR +Y  D+KSKEMR+RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLH  KDGK+Y V FDFLGKDSIRY+N VPVEKRVFKN+QLFMENK   DDLFDRLNTT++N++LN LM+GLTAKVFRT+NAS+TLQ QL++LT  DD    K+LSYNRANR VAILCNHQR+ PKTH KSM+NL+ KI+AK++A   AE  +K AK+  K+ GS  EKV  +KKKKAL+R  EQL KLE QA DKEENK IALGTSKLNYLDPRI+VAW KK +VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct:  370 IKTEEESDEDVPLSARSMAPTSIKRSLDSEEEEDVPLSARKKSKKSDTKTKKKKRKYEDDEDEDEIEQK---PKKKGARTSKGENSSPRKKKQEEEQEVWKWWEEEKKNDGTKWTFLEHKGPVFAPPYEPLPPDVNFYYNGKEMKLSQDTEEVATFYARMLDHDYTTKPAFNSNFFHDWREVMTESERTKIVDLSKCNFKEIHAYFIQKSEERKAMTKEEKQKIKEKNEEIQKEYGYCIIDGHKEKIGNFKIEPPGLFRGRGEHPKMGKLKKRVMPEDILINCSKDSNIPKPPPGHKWKEIRHDPNVTWLASWTENIQGQVKYVMLNPSSKLKGEKDWQKYEIARKLAQLIDKIRAEYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKSPSDDLFDRLNTTVMNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTNPDDTEAEKILSYNRANRAVAILCNHQRSVPKTHAKSMENLKAKIEAKKQAINDAELAVKDAKRDAKH-GSVKEKVTYEKKKKALDRLKEQLTKLEVQATDKEENKEIALGTSKLNYLDPRITVAWCKKHNVPIEKIYNKTQRDKFRWAIDMAGPDYVF 1026          

BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: EEB15907.1 (DNA topoisomerase, putative [Pediculus humanus corporis])

HSP 1 Score: 694.886 bits (1792), Expect = 0.000e+0
Identity = 376/646 (58.20%), Postives = 461/646 (71.36%), Query Frame = 0

Query:  269 QDDSEDDIPLAKKSKNKKRKSR-DEDSEDDVPLSKRKKPKVKKVERVEVSKKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFM---------------DRKYSKS------NQIRH------VKSFLKIKRGKGYY------------------EKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            Q+DS+DD    KK+K KKRKS+ D DSEDD       KP  KK  +  + K+ K        K    SP K    KK+E++ +VWKWWEEEK +DG KWKFL+H+GPLFAP Y+RLPK V F+Y+ K++ LS E EEVA FYA+ + H+YT KE FN NFF DWRKVMT +ER +IT+LSKC+F+ +  Y+++ SEERK  SKEEKK  K++N AIQ E+G C ID H EKIGNFRIEPPGLFRGR     +G +               D K  K        +++H      + S+ +  +G   Y                  E AR+L  KI+KIR+ Y  D+KSKEM++RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEH+ L+   +GK+  V FDFLGKDSIRY+N VPVEKRVFKN+ LF ENK+ +DDLFDRLNTT+LN++LN LM+GLTAKVFRT+NAS+TLQ+QL+ELT  DD V  K+L+YNRANR VAILCNHQR+ PK+H+KSM+NL+ KI+AKRE   + +K++K AK   +NG S +E     KKKK L+R  EQL KLE Q  DKEENKTIALGTSKLNYLDPRISVAW KK++VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct:  340 QEDSDDDFKPGKKTKGKKRKSKGDSDSEDDF------KPAAKKPSKTVIKKEVK--------KETTTSPKKV---KKEEEQQDVWKWWEEEKREDGKKWKFLEHKGPLFAPLYERLPKSVKFFYDGKEISLSEEAEEVATFYAKMLTHDYTTKEKFNTNFFNDWRKVMTDKERKVITDLSKCNFKPMALYFQEKSEERKAMSKEEKKVIKDQNDAIQKEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGMLKKRVLPEDVIINCSKDSKIPKPPDGHKWKKVQHDPSVTWLASWTENVQGNVKYVMLNPSSKLKGEKDMVKYETARKLAKKIDKIREQYQADWKSKEMKIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVELYPELNGKENVVVFDFLGKDSIRYYNEVPVEKRVFKNLLLFKENKQPQDDLFDRLNTTVLNKHLNELMEGLTAKVFRTYNASWTLQEQLKELTNPDDTVAEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKAKIEAKREQINEIKKEVKNAK---RNGDSGTEA----KKKKQLDRLKEQLLKLEVQETDKEENKTIALGTSKLNYLDPRISVAWCKKYNVPIEKIYNKTQRDKFRWAIDMAGPDYVF 961          

BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: XP_016770482.1 (PREDICTED: DNA topoisomerase 1 isoform X2 [Apis mellifera])

HSP 1 Score: 666.381 bits (1718), Expect = 0.000e+0
Identity = 350/559 (62.61%), Postives = 416/559 (74.42%), Query Frame = 0

Query:  355 WEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLF--RGRYL-VGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            WEEEK +DGTKW FL+H+GP+FAP Y+ LP  V+FYYN K+MKLS +TEEVA FYAR ++H+YT K  FN NFF DWR+VMT  ER  I +LSKC+F+EI+ Y+ + SEERK  +KEEK+  KEKN  IQ E+G C+ID H EKIGNF+IEPPGLF  RG +  +G + ++                       K  +IRH                 VK  +     K+K  K +  YE AR+L   I+KIR +Y  D+KSKEMR+RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLH  KDGK+Y V FDFLGKDSIRY+N VPVEKRVFKN+QLFMENK   DDLFDRLNTT++N++LN LM+GLTAKVFRT+NAS+TLQ QL++LT  DD    K+LSYNRANR VAILCNHQR+ PKTH KSM+NL+ KI+AK++A   AE  +K AK+  K+ GS  EKV  +KKKKAL+R  EQL KLE QA DKEENK IALGTSKLNYLDPRI+VAW KK +VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct:   17 WEEEKKNDGTKWTFLEHKGPVFAPPYEPLPPDVNFYYNGKEMKLSQDTEEVATFYARMLDHDYTTKPAFNSNFFHDWREVMTESERTKIVDLSKCNFKEIHAYFIQKSEERKAMTKEEKQKIKEKNEEIQKEYGYCIIDGHKEKIGNFKIEPPGLFRGRGEHPKMGKLKKRVMPEDILINCSKDSNIPKPPPGHKWKEIRHDPNVTWLASWTENIQGQVKYVMLNPSSKLKGEKDWQKYEIARKLAQLIDKIRAEYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKSPSDDLFDRLNTTVMNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTNPDDTEAEKILSYNRANRAVAILCNHQRSVPKTHAKSMENLKAKIEAKKQAINDAELAVKDAKRDAKH-GSVKEKVTYEKKKKALDRLKEQLTKLEVQATDKEENKEIALGTSKLNYLDPRITVAWCKKHNVPIEKIYNKTQRDKFRWAIDMAGPDYVF 574          

BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: EGK96321.1 (AGAP004078-PB [Anopheles gambiae str. PEST])

HSP 1 Score: 652.899 bits (1683), Expect = 0.000e+0
Identity = 332/559 (59.39%), Postives = 402/559 (71.91%), Query Frame = 0

Query:  355 WEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYSKSN---------------------QIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            WEEEK DDG KWK+L+H+GP+FAP YD LP  V F Y+ K+MKLS + EEVAGFYAR +EH+YT K+ FN NFFKDWRK MT  ER+ IT+L KC+FR +  Y+ +++E+ +NRSKEEK A K  N  +  E+GICVID H EKIGNF+IEPPGLFRGR     +G + R+    +                     ++RH                 VK  +     K+K  K +  YE AR L   I+KIRD Y  ++KSKEMR+RQR+VA+YFIDKLALRAGNEKD+DQADTVGCCSLR EHI LH   +GK+  V FDFLGKDSIRY+N V VEKRVFKN++LF ENK+  DDLFDRLNT+++NEYL  LM GLTAKVFRTFNAS+TLQ QLEELT+ + +VP K+L+YNRANR VAILCNHQRA PKTH+KSM NL++KI+ KRE  E+ +K+ K  KK+     +  +    DKK K LER  EQL KLE Q  D++ENKTIALGTSKLNYLDPRISVAW KKF VPIEK++NKTQRDKFRWAI+MA  +YVF
Sbjct:   28 WEEEKRDDGVKWKYLEHKGPVFAPPYDPLPSHVKFMYDGKEMKLSQDAEEVAGFYARMLEHDYTSKQAFNDNFFKDWRKTMTPHERERITDLEKCNFRPMAAYFAEIAEQNRNRSKEEKAALKAANEQLTKEYGICVIDGHKEKIGNFKIEPPGLFRGRGEHPKMGLVKRRVMPEDVIINCSQDSKIPSPPPGRRWKEVRHDNTVSWLASWVENVQGQVKYIMLNPSSKLKGEKDWQKYETARRLLKHIDKIRDTYRDEWKSKEMRIRQRAVAMYFIDKLALRAGNEKDDDQADTVGCCSLRYEHIALHKELNGKENVVVFDFLGKDSIRYYNEVEVEKRVFKNLELFKENKKPGDDLFDRLNTSVVNEYLKGLMDGLTAKVFRTFNASYTLQKQLEELTDPNMSVPEKLLAYNRANRAVAILCNHQRAVPKTHEKSMGNLKEKIRVKREQVEQCQKEFKDLKKS-----NVRDPSAFDKKSKQLERLKEQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKFGVPIEKIFNKTQRDKFRWAIDMADENYVF 581          

BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: EAA05377.5 (AGAP004078-PA [Anopheles gambiae str. PEST])

HSP 1 Score: 651.744 bits (1680), Expect = 0.000e+0
Identity = 327/553 (59.13%), Postives = 397/553 (71.79%), Query Frame = 0

Query:  361 DDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYSKSN---------------------QIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            DDG KWK+L+H+GP+FAP YD LP  V F Y+ K+MKLS + EEVAGFYAR +EH+YT K+ FN NFFKDWRK MT  ER+ IT+L KC+FR +  Y+ +++E+ +NRSKEEK A K  N  +  E+GICVID H EKIGNF+IEPPGLFRGR     +G + R+    +                     ++RH                 VK  +     K+K  K +  YE AR L   I+KIRD Y  ++KSKEMR+RQR+VA+YFIDKLALRAGNEKD+DQADTVGCCSLR EHI LH   +GK+  V FDFLGKDSIRY+N V VEKRVFKN++LF ENK+  DDLFDRLNT+++NEYL  LM GLTAKVFRTFNAS+TLQ QLEELT+ + +VP K+L+YNRANR VAILCNHQRA PKTH+KSM NL++KI+ KRE  E+ +K+ K  KK+     +  +    DKK K LER  EQL KLE Q  D++ENKTIALGTSKLNYLDPRISVAW KKF VPIEK++NKTQRDKFRWAI+MA  +YVF
Sbjct:  541 DDGVKWKYLEHKGPVFAPPYDPLPSHVKFMYDGKEMKLSQDAEEVAGFYARMLEHDYTSKQAFNDNFFKDWRKTMTPHERERITDLEKCNFRPMAAYFAEIAEQNRNRSKEEKAALKAANEQLTKEYGICVIDGHKEKIGNFKIEPPGLFRGRGEHPKMGLVKRRVMPEDVIINCSQDSKIPSPPPGRRWKEVRHDNTVSWLASWVENVQGQVKYIMLNPSSKLKGEKDWQKYETARRLLKHIDKIRDTYRDEWKSKEMRIRQRAVAMYFIDKLALRAGNEKDDDQADTVGCCSLRYEHIALHKELNGKENVVVFDFLGKDSIRYYNEVEVEKRVFKNLELFKENKKPGDDLFDRLNTSVVNEYLKGLMDGLTAKVFRTFNASYTLQKQLEELTDPNMSVPEKLLAYNRANRAVAILCNHQRAVPKTHEKSMGNLKEKIRVKREQVEQCQKEFKDLKKS-----NVRDPSAFDKKSKQLERLKEQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKFGVPIEKIFNKTQRDKFRWAIDMADENYVF 1088          

BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: EFX74248.1 (hypothetical protein DAPPUDRAFT_109061 [Daphnia pulex])

HSP 1 Score: 635.565 bits (1638), Expect = 0.000e+0
Identity = 325/522 (62.26%), Postives = 394/522 (75.48%), Query Frame = 0

Query:  355 WEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYSKSNQIRHVKSFLKIKRGKGY-YEKARE------LKSKIEKIRD-DYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            WEEEK +DG KWK L+H+GP+FA  Y+ LP  V F YN ++MKLS+  EEV  FYA  ++H+Y  K+VFN+NFFKDWRK MT  E++IIT+L KCDF  + TY+K  SEERKNR+KEEK   K +N  +  E+G C+ID H ++IGNF+IEPPGLFRGR     +G + R+    + I +       K   G+ +++ R       L S  E ++   Y  D+KSKEM++RQRSVALYFIDKLALRAGNEKDEDQADTVG CSLRVEHI+LH  K+GK   V FDFLGKDSIRY+N VPVEKRVFKN+Q+FMENK+  DDLFDRLNTTI+N++LN LM+GLTAKVFRTFNAS TLQ+QL+ELT+   +V  K+L+YNRANR VAILCNHQRA PKT  KSM+NLQ KI AKREA E AEK  K  KK  K  GS + K+   KK+K +E+  EQL KLE QA D+EENK IALGTSKLNYLDPRISVAW KK DVPIEK+YNKTQR+KF+WAI+MAG ++VF
Sbjct:   22 WEEEKHEDGVKWKSLEHKGPVFATQYEPLPGNVKFKYNGQEMKLSTAAEEVGSFYAAMLDHDYVTKDVFNKNFFKDWRKFMTHSEKEIITDLKKCDFTYMLTYFKAKSEERKNRTKEEKLQLKTENEEMVKEYGWCIIDGHKQRIGNFKIEPPGLFRGRGDHPKMGMVKRRVMPEDVIINCTKGTAPKPPPGHKWKEVRSDNTVTWLASWTENVQGQTYKEDWKSKEMKIRQRSVALYFIDKLALRAGNEKDEDQADTVGACSLRVEHISLHEQKEGKQCVVVFDFLGKDSIRYYNEVPVEKRVFKNLQIFMENKKPGDDLFDRLNTTIMNKHLNDLMEGLTAKVFRTFNASNTLQEQLDELTDPKSSVTEKILAYNRANRAVAILCNHQRAVPKTFAKSMENLQVKITAKREAIEDAEKSFKDLKKEAKKTGSAAAKIAAGKKEKQVEKLKEQLMKLEVQATDREENKEIALGTSKLNYLDPRISVAWCKKNDVPIEKIYNKTQREKFQWAIDMAGPEFVF 543          

BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: gb|KPM06386.1| (DNA topoisomerase 1-like protein [Sarcoptes scabiei])

HSP 1 Score: 619.772 bits (1597), Expect = 0.000e+0
Identity = 327/564 (57.98%), Postives = 396/564 (70.21%), Query Frame = 0

Query:  351 VWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR-----------------YLVGFMDRKYS-------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            +WKWWEEE+  +G KWK L+H GP+F PDY+ LPK V FYYN K M+LS   EEVA FYA+ ++H+YT K+VFN+NFFKDWRK MT +E++IIT+LS C+F+++N Y+K  +E+RK  +KEEK   K+KN     ++G C++D H +KIGNFRIEPPGLFRGR                  ++   D+  +       K  +IRH                 VK  +     K+K  K +  YEKARELK  + KIR DY  DFKS EM  RQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHITL+  K+G  Y V+FDFLGKDSIRY N V VEKRVFKN++ F+++K+  DDLFDRL T+ LN+YLNSLM GLTAKVFRT+NAS TLQ QL ELT+AD N+P KML+YNRANR VA+LCNHQRA PKT DK M+NL  KI+ K+         +K+ KK YK   S  +    DK KK L+   EQL KLE Q VDKEENK IALGTSKLNYLDPRISVAW KK+ VPI+K+YNKTQRDKFRWAIEM G DY F
Sbjct:  218 IWKWWEEERPGEGIKWKTLEHNGPVFPPDYEPLPKNVKFYYNGKHMELSPGAEEVASFYAKMLDHDYTSKDVFNKNFFKDWRKTMTDKEKEIITDLSLCNFKKMNEYFKDQTEKRKQMTKEEKLEIKKKNEEAVLKYGYCIVDGHKQKIGNFRIEPPGLFRGRGEHPKMGKLKKRVQPEDIIINIGDKAKAPIPPAGHKWKEIRHDNTVTWLASWTENIMGNVKYIMLNPSSKLKSIKDWQKYEKARELKKYVAKIRADYRTDFKSHEMMKRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHITLNEEKNGNQYVVDFDFLGKDSIRYINSVSVEKRVFKNLKHFIQHKQPGDDLFDRLTTSSLNKYLNSLMDGLTAKVFRTYNASNTLQQQLNELTKADMNLPEKMLAYNRANRSVALLCNHQRAVPKTFDKQMENLSVKIQDKKSQ-------IKEQKKIYKE--SKGDSAARDKHKKKLKTLEEQLKKLEVQKVDKEENKQIALGTSKLNYLDPRISVAWCKKWQVPIDKIYNKTQRDKFRWAIEMVGPDYQF 772          

BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: AHN59737.1 (topoisomerase 1, isoform E [Drosophila melanogaster])

HSP 1 Score: 606.29 bits (1562), Expect = 0.000e+0
Identity = 316/561 (56.33%), Postives = 387/561 (68.98%), Query Frame = 0

Query:  353 KWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYSKS---------------------------NQIRHVKSFLKIKRG-------------KG-----YYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            +WWEEEK  DG KW  L+H+GP+FAP Y+R+P+ V FYY+ K ++LS ETEE A FYA+ + H+Y  KEVFN NFFKD+RK MT  ER+II +  KC+F+E+  Y++  SE+RK  SKEEK  +K +N A+  EFG C+ID H EKIGNFR+EPPGLFRGR     +G + R+   S                           N +  + S+++  +G             KG      YE AR L   I+KIR  Y  ++KSKEMRVRQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEH+ LH   +GK+  V FDF GKDSIRY+N V VEKRVFKN++LFME+K+  DDLFDRLNT +LNE+L  LM+GLTAKVFRT+NAS TLQ QL+ LT+    VP K+L+YNRANR VAILCNHQR+ PK+H+KSM+NL++KIKAKREA EK E +                    +KK K LER  +QL KLE Q  D++ENKTIALGTSKLNYLDPRISVAW KK DVPIEK++NKTQR KF WA+ MA  +Y F
Sbjct:   48 RWWEEEKRADGVKWSTLEHKGPVFAPRYERVPRNVRFYYDGKPLELSEETEEAATFYAKMLNHDYCTKEVFNNNFFKDFRKSMTPREREIIKDFRKCNFQEMFNYFQAESEKRKAASKEEKLIKKNENEALMKEFGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIQASDVSINCGKDSKVPSPPPGSRWKEVRHDNTVTWLASWIENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLELFMEHKKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEKIKAKREAIEKCESEYHSRD---------------EKKGKQLERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQRTKFLWAVHMADENYRF 593          

BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: AFH07393.1 (topoisomerase 1, isoform D [Drosophila melanogaster])

HSP 1 Score: 595.504 bits (1534), Expect = 0.000e+0
Identity = 311/552 (56.34%), Postives = 383/552 (69.38%), Query Frame = 0

Query:  362 DGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYSKSN---------------------QIRH------VKSFLKIKRG-------------KG-----YYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            DG KW  L+H+GP+FAP Y+R+P+ V FYY+ K ++LS ETEE A FYA+ + H+Y  KEVFN NFFKD+RK MT  ER+II +  KC+F+E+  Y++  SE+RK  SKEEK  +K +N A+  EFG C+ID H EKIGNFR+EPPGLFRGR     +G + R+   S+                     ++RH      + S+++  +G             KG      YE AR L   I+KIR  Y  ++KSKEMRVRQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEH+ LH   +GK+  V FDF GKDSIRY+N V VEKRVFKN++LFME+K+  DDLFDRLNT +LNE+L  LM+GLTAKVFRT+NAS TLQ QL+ LT+    VP K+L+YNRANR VAILCNHQR+ PK+H+KSM+NL++KIKAKREA EK E +                    +KK K LER  +QL KLE Q  D++ENKTIALGTSKLNYLDPRISVAW KK DVPIEK++NKTQR KF WA+ MA  +Y F
Sbjct:  434 DGVKWSTLEHKGPVFAPRYERVPRNVRFYYDGKPLELSEETEEAATFYAKMLNHDYCTKEVFNNNFFKDFRKSMTPREREIIKDFRKCNFQEMFNYFQAESEKRKAASKEEKLIKKNENEALMKEFGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIQASDVSINCGKDSKVPSPPPGSRWKEVRHDNTVTWLASWIENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLELFMEHKKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEKIKAKREAIEKCESEYHSRD---------------EKKGKQLERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQRTKFLWAVHMADENYRF 970          

BLAST of EMLSAG00000000293 vs. nr
Match: gi|343175107|gb|AEM00018.1| (topoisomerase 1B [Spodoptera exigua])

HSP 1 Score: 724.546 bits (1869), Expect = 0.000e+0
Identity = 380/663 (57.32%), Postives = 469/663 (70.74%), Query Frame = 0

Query:  265 EVKVQDDSEDDIPLAKKSKNKKRKSRDEDSEDDVPLSKRKK--------PKVKKVERVEVSKKSKSSKKNHKVKHEVV------SPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFM---------------DRKYSKS------------NQIRHVKSFLKIKRGKGYY------------------EKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            E+  +++S++D P +++  NK+R     +SE+D+PL +RKK        P        E  K  K   K  KVK   V       P+ +  +KK+ED+ EVWKWWEEEK DDGTKWKFL+H+GP+FAPDY+ LP+ V FYY+ K+M+LS + EEVAGFYAR ++HEYT K  FN NFF DWRKVMT EE  II +LSKC+F+E++ Y++ VSE+ +NR+KEEK A K KN  IQ E+G C+ID H EKIGNFRIEPPGLFRGR     +G +               D K  K             N +  + S+ +  +G+  Y                  E AR+L   I+ IR++Y  D+K+KEMRVRQR+VALYFIDKLALRAGNEKD+DQADTVGCCSLRVEHI LH  KDGK+Y V FDFLGKDSIRY+N VPVEKRVFKN++LFMENK+  DDLFDRLNT  LNE+L  LM GLTAKVFRT+NAS TLQ QL+ELT+A  ++P K+L+YNRANR VA+LCNHQRA PK H KSM+ L++KI+AKR+  ++AE+DL++A KA K  GS  EK+  DKKKKALER  EQL KLE Q  D++ENKTIALGTSKLNYLDPRISVAW KK  VPIEK+YNKTQRDKFRWAI+MAG +Y+F
Sbjct:  271 ELPPEEESDEDSPSSERIGNKRRAP--SESEEDIPLLQRKKSKKKIKKEPTYDDDMDDEEEKPKKKKSKPVKVKQTQVKSEPNDGPSPTKRKKKQEDEPEVWKWWEEEKKDDGTKWKFLEHKGPVFAPDYEPLPENVKFYYDGKEMRLSQDAEEVAGFYARMLDHEYTTKSTFNNNFFNDWRKVMTHEETKIIKDLSKCNFKEMHAYFQSVSEKNRNRTKEEKAALKAKNEEIQKEYGFCIIDGHKEKIGNFRIEPPGLFRGRGEHPKMGMLKRRVMPEDVLINCSKDSKIPKPPPGHKWKEVKHDNTVTWLASWTENVQGQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDVIRENYKNDWKAKEMRVRQRAVALYFIDKLALRAGNEKDDDQADTVGCCSLRVEHIALHKEKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLELFMENKKDSDDLFDRLNTQTLNEHLKDLMPGLTAKVFRTYNASITLQRQLDELTDASASIPEKILAYNRANRAVAVLCNHQRAVPKGHSKSMEALKEKIQAKRDQVDEAEEDLREAAKAAKR-GSVKEKLACDKKKKALERLREQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHGVPIEKIYNKTQRDKFRWAIDMAGPEYIF 930          

BLAST of EMLSAG00000000293 vs. nr
Match: gi|939676204|ref|XP_014284042.1| (PREDICTED: DNA topoisomerase I, mitochondrial [Halyomorpha halys])

HSP 1 Score: 723.391 bits (1866), Expect = 0.000e+0
Identity = 426/843 (50.53%), Postives = 558/843 (66.19%), Query Frame = 0

Query:   86 KEKERREREERHKREGRRDETEEERKVRKEKERKEREERHKREGRRDETEDERRLRKERERKEREERHKREGRREETEEERKARKEKEQRHKSKETEEERRVRKDKERAEKEARKRKEMGYDHSMGEEVSFHNHDEEMKMEQQEQQVKDEPQYEEELHEEQDEFEEDRYNN--AKQENMEVEVKVQDDSEDDIPLAKKSKNKKRKSRDEDSEDDVPLSKRKKPKVKKVERVEVSKKSKSSKKNHKVKH-------------EVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            KEK R + ++RH R+ +RD+        K+K++         + +       +   KE+   + ++R  R+  R+  +++ +++   +++H S  +    + +KDKER+++   KR E  ++ +   + S  + +E + ++ +   +K+EP  +  L E+Q+      YNN   K+E  E E   Q+DSEDD PL  ++ N KR+ + ED E+D+PLS RKK K +K  + +     +    + K                E    T    +KK+E++ EVWKWWEEEK  DG KW FL+H+GP+FAP Y+ LP  V F+Y+ K+MKLS E EEVA FY R I+HEYT KE FN+NFFKDWRKVMT++E+D+IT+L KC+FR+INTY+ + SEERK  SKEEKK  KEKN  +  E+G C+ID H EKIGNF+IEPP LFRGR     +G + R+                       K  ++RH                 VK  +     K+K  K +  YE AR+L   I+KIR DY  D+KSKEMR+RQR+VA+YFID LALRAGNEKDEDQADTVGCCSLRVEHITLH  KDGK+Y V FDFLGKDSIRY+N VP+EKRVFKN+QLFME K+G DDLFDRLNT+ILN++LN LM+GLTAKVFRT+NAS+TLQ QL+ELT+ +  VP  +L+YNRANR VAILCNHQR+ PKTH  SM+ L++KI AK++  E+AEK  K AKK  KN GS  E++V DKKKKAL+R  EQL KLE Q  D+EENKTIAL TSKLNYLDPRISVAW KK++VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct:  110 KEKHREKDKDRH-RDEKRDKEHRSSSSHKDKDKHSSTNSSSSKDKDKSHSSSKDKDKEKNSSKDKDRSDRDKHRDREKDKDRSKHNGDRKHSSSSSSSREKEKKDKERSKEAKPKRDE--FEEADDFQPSKVSEEEPVVVKSEPVDIKEEPIDDSYLSEDQNSC----YNNLTIKEEEDEAEEPQQEDSEDDAPLLSRTSNIKREIKSEDEEEDIPLSARKKVKKEKTGKRKKESDDEEEDDDFKPVKKKSSTVKKTKVKTEAPEETSPKKKKKQEEEQEVWKWWEEEKRPDGVKWTFLEHKGPVFAPPYEPLPPDVKFFYDGKEMKLSEEAEEVATFYGRMIDHEYTTKEAFNKNFFKDWRKVMTQKEKDVITDLKKCNFRQINTYFLRKSEERKAMSKEEKKVIKEKNEELVKEYGFCIIDGHKEKIGNFKIEPPSLFRGRGEHPKMGMLKRRVQPEDVLINCSKDSKIPKPPEGHKWKEVRHDNTVTWLASWTENVQGQVKYVMLNPSSKLKGEKDWQKYETARKLAHSIDKIRKDYREDWKSKEMRIRQRAVAMYFIDILALRAGNEKDEDQADTVGCCSLRVEHITLHNEKDGKEYVVVFDFLGKDSIRYYNEVPIEKRVFKNLQLFMEGKKGSDDLFDRLNTSILNKHLNELMEGLTAKVFRTYNASWTLQQQLKELTDPNYTVPEMVLAYNRANRAVAILCNHQRSVPKTHQNSMEKLKEKIAAKKDQIEEAEKQYKYAKKDAKN-GSAKERIVADKKKKALDRLREQLTKLEVQETDREENKTIALSTSKLNYLDPRISVAWCKKYNVPIEKIYNKTQRDKFRWAIDMAGPDYVF 944          

BLAST of EMLSAG00000000293 vs. nr
Match: gi|939255986|ref|XP_014247767.1| (PREDICTED: DNA topoisomerase I, mitochondrial isoform X1 [Cimex lectularius])

HSP 1 Score: 721.85 bits (1862), Expect = 0.000e+0
Identity = 394/695 (56.69%), Postives = 482/695 (69.35%), Query Frame = 0

Query:  238 YEEELHEEQDEFEEDRYNNAKQENME-VEVKVQDDSEDDIPLAKKSKNKKRKSRDEDSEDDVPLSKRKKPKVKKVERVEVSK----------------KSKSSKKNHKVKHEVVSPTKSGGRKKK--EDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYSKSN-----------------------------------------QIRHV----KSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            Y+E   +E+D+  +D YN   +  ME    K ++DSE+DIPL+ +     + S   D +DDVPL+ RKK K +K +  +  K                K+K+ KK+ KVK E  +      RKK+  E++ EVWKWWEEEK  DG KW FL+H+GP+FAP Y+ LP  V FYY+ K+++LS E EEVA FY R IEH+YT+KEVFN NFFKDW+K MT +ER++IT+LSKC+FR IN Y++K SEERK  +KEEK   K+KN     E+G C+ID H EKIGNF+IEPP LFRGR     +G + ++    +                                         Q+++V     S LK ++    YE AR+L S+I+KIR DY  D+KSKEM++RQR+VA+YFIDKLALRAGNEKDEDQADTVGCCSLRVEHI L   KDGK+Y V FDFLGKDSIRY+N VPVEKRVFKN+QLF+E K+G DDLFDRLNTT+LN++L  LM GLTAKVFRT+NAS+TLQ QL ELT+ D  +P   L+YNRANR VAILCNHQR+ PK+H KSM+NL++KI  KRE  E+AEK  K AKK  KN GS  EK+V DKKKKALER  EQL KLE Q  D+EENKTIALGTSKLNYLDPRISVAW KK +VPIEKVYNKTQRDKFRWAI+MAG DYVF
Sbjct:  288 YDENDFKEEDD--DDSYNLHIETTMEESTFKEEEDSEEDIPLSSR-----KHSMQSDEDDDVPLTSRKKLKTEKQKSSKKRKKSFDSEEEEEDDFKPVKTKAQKKSSKVKQEQNTSATQSPRKKRKLEEEQEVWKWWEEEKKPDGVKWNFLEHKGPVFAPPYEPLPHDVKFYYDGKEVRLSEEAEEVATFYGRMIEHDYTQKEVFNNNFFKDWKKTMTPKERELITDLSKCNFRHINAYFQKKSEERKAMTKEEKAELKKKNEEQVQEYGFCIIDGHKEKIGNFKIEPPSLFRGRGEHPKMGMLKKRVMPEDVSINCSKDSKIPVPPPGHKWKEVKHDNTVTWLASWTENVQGQVKYVMLNPSSKLKGEKDWQKYETARKLASQIDKIRRDYREDWKSKEMKIRQRAVAMYFIDKLALRAGNEKDEDQADTVGCCSLRVEHIQLFPEKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFIEGKKGSDDLFDRLNTTVLNKHLTELMDGLTAKVFRTYNASWTLQQQLNELTKDDYTLPEMCLAYNRANRAVAILCNHQRSVPKSHQKSMENLKEKISNKREQIEEAEKQYKYAKKDAKN-GSAKEKIVADKKKKALERLKEQLRKLEVQETDREENKTIALGTSKLNYLDPRISVAWCKKHNVPIEKVYNKTQRDKFRWAIDMAGPDYVF 974          

BLAST of EMLSAG00000000293 vs. nr
Match: gi|307182085|gb|EFN69463.1| (DNA topoisomerase 1 [Camponotus floridanus])

HSP 1 Score: 721.85 bits (1862), Expect = 0.000e+0
Identity = 424/855 (49.59%), Postives = 548/855 (64.09%), Query Frame = 0

Query:  107 EEERKVRKEKERKEREERHKREGRRDE---TEDERRLRKERERKEREERHK-REGRREETEEERKARKEKEQRHKSKETEEERRVRKDKERAEKEARKRKEMGYDHSMGEEVSFHNHDEEMKMEQQEQQVKDEPQYEEELHEEQDEF--------EEDRYNNAKQENMEVE----------------VKVQDDSEDDIPLAKKSKNKKRKSR--DEDSEDDVPLSKRKKPKVKKV---------------ERVEVSKKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR-----------------------------------------------YLVGFMDRKYSKSNQIRHV----KSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            +++R + K+KER+ +  +H   G RD+   +       KE+ R   +++ K RE      +++ +  K+K++    K    + + ++DK++ E + ++  +M  +H+  E   FH ++ E+K E     +K+EP  + EL E+ D          EED    A +E   ++                +K ++DSE+D PL+ +SK      R  + D E+DVPLS RKKPK                   +  EV  + KS KK  + K E  SP K    +K+E++ EVWKWWEEEK  DGTKW FL+H+GP+FAP Y+ LP  V FYYN K+ KLS + EEVA FYAR ++H+YT K+ FN NFF DWR+VMT  ER  IT+LSKC+F+E++ Y+ + SEERK  +KEEK+  KEKN  IQ E+G CVID H EKIGNF+IEPPGLFRGR                                               +L  + +   +   Q+++V     S LK ++    YE AR+L   I+KIR +Y  D+KSKEMR+RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHI LH  +DGK+Y V FDFLGKDSIRY+N VPVEKRVFKN+QLFMENK   DDLFDRLNTT++N++LN LM+GLTAKVFRT+NAS+TLQ QL++LT+ +D    K+LSYNRANR VAILCNHQR+ PKTH KSM+NL+ KI AK+EA  + E  +K AK+  K+ GS  EKV  +KKKK LER  EQL KLE QA D+EENK IALGTSKLNYLDPRISVAW KK +VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct:  203 DKDRNLSKDKERENK--KHSSSGERDKDRHSTSHSSGDKEKHRSSEKDKDKHRESSSSSKDKQHRHEKDKDRHRHDKSKHRDEKEKRDKDKEEIKIKEETDMKLNHATNER--FH-YNLEVKPE-----IKEEPMTQLELDEDDDSGGERPLYIKEEDDDEEAVKEEASMDSTDGNDTRLSDLHNTTLKTEEDSEEDKPLSSRSKVSPSVKRKIESDEEEDVPLSARKKPKRATSSKTKKKKRKHDGENDDDSEVESEEKSKKKV-RAKGEGASPRK----RKQEEEQEVWKWWEEEKKSDGTKWHFLEHKGPVFAPPYEPLPPNVKFYYNGKETKLSQDAEEVATFYARMLDHDYTTKDAFNNNFFHDWREVMTESERAKITDLSKCNFKEMHAYFLQKSEERKAMTKEEKQKIKEKNDEIQKEYGFCVIDGHKEKIGNFKIEPPGLFRGRGEHPKMGKLKKRVLPEDVLINCSKDSNIPKPPAGHKWKEVRHDPNVTWLASWTE---NIQGQVKYVMLNPSSKLKGEKDWQKYETARKLAQSIDKIRAEYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHIKLHEQRDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKSPGDDLFDRLNTTVMNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTDPNDTEAEKILSYNRANRAVAILCNHQRSVPKTHAKSMENLKAKIDAKKEAIAECELQVKDAKRDAKH-GSVKEKVTYEKKKKQLERLKEQLTKLEVQATDREENKEIALGTSKLNYLDPRISVAWCKKHNVPIEKIYNKTQRDKFRWAIDMAGPDYVF 1038          

BLAST of EMLSAG00000000293 vs. nr
Match: gi|350404638|ref|XP_003487171.1| (PREDICTED: DNA topoisomerase I, mitochondrial [Bombus impatiens])

HSP 1 Score: 721.079 bits (1860), Expect = 0.000e+0
Identity = 388/701 (55.35%), Postives = 492/701 (70.19%), Query Frame = 0

Query:  227 QQEQQVKDEPQYEEELHEEQDEFEEDRYNNAKQENME-VEVKVQDDSEDDIPLAKKS--KNKKRKSRDEDSEDDVPLSKRKKPKVKKVERVEVSKKSKSSKKNHKVKHEVVSPTKSGGR-----------KKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKY---------------------SKSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            +Q   +K++   EE ++EE+   +    N+ +  ++    +K +++S++D+PL+ +S      ++S D + EDDVPLS RKK K    +  +  +K +  +   +++ +   P K GGR           KK+E++ EVWKWWEEEK +DGTKW FL+H+GP+FAP Y+ LP  V FYY  K+MKLS + EEVA FYAR ++H+YT K  FN NFF DWR+VMT  ER  I +LSKC+F+E+++Y+ + SEERK  +KEEK+  KE N  IQ E+G C+ID H EKIGNF+IEPPGLFRGR     +G + R+                       K  ++RH                 VK  +     K+K  K +  YE AR+L   I+KIR +Y  D+KSKEMR+RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLH  KDGK+Y V FDFLGKDSIRY+N VPVEKRVFKN+QLFMENK   DDLFDRLNTT++N++LN LM+GLTAKVFRT+NAS+TLQ QL++LT  DD    K+LSYNRANR VAILCNHQR+ PKTH KSM+NL+ KI+AK++A  +AE  +K+AK+  K+ GS  EKVV +KKKKAL+R  EQL KLE QA DKEENK IALGTSKLNYLDPRI+VAW KK +VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct:  332 EQPLYIKEDDDDEEAMNEEEGSMDSTDGNDTRLSDLHNTTIKTEEESDEDMPLSARSMAPTSVKRSLDSEEEDDVPLSARKKSKKNDTKAKKKKRKHEDDEDEDEIEQK---PKKKGGRASKGENSSPRKKKQEEEQEVWKWWEEEKKNDGTKWTFLEHKGPVFAPPYEPLPPDVKFYYCGKEMKLSQDAEEVATFYARMLDHDYTTKSAFNNNFFHDWREVMTESERAKINDLSKCNFKEMHSYFVQKSEERKAMTKEEKQKIKETNEQIQKEYGFCIIDGHKEKIGNFKIEPPGLFRGRGEHPKMGKLKRRVMPEDILINCSKDSNIPKPPPGHKWKEVRHDPNVTWLASWTENIQGQVKYVMLNPSSKLKGEKDWQKYETARKLAQLIDKIRAEYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKSPSDDLFDRLNTTVMNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTNPDDTEAEKILSYNRANRAVAILCNHQRSVPKTHAKSMENLKAKIEAKKQAISEAEHAVKEAKRDAKH-GSVKEKVVYEKKKKALDRLKEQLTKLEVQATDKEENKEIALGTSKLNYLDPRITVAWCKKHNVPIEKIYNKTQRDKFRWAIDMAGPDYVF 1028          

BLAST of EMLSAG00000000293 vs. nr
Match: gi|987905862|ref|XP_015440538.1| (PREDICTED: DNA topoisomerase I, mitochondrial isoform X1 [Dufourea novaeangliae] >gi|1016159729|gb|KZC06891.1| DNA topoisomerase 1 [Dufourea novaeangliae])

HSP 1 Score: 720.694 bits (1859), Expect = 0.000e+0
Identity = 390/664 (58.73%), Postives = 476/664 (71.69%), Query Frame = 0

Query:  266 VKVQDDSEDDIPLAKKSK---NKKRKSRDEDSEDDVPLSKRKKPK-------VKKV------ERVEVSKKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR-----------------YLV-----GFMDRKYS--KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            +K +++S++D+PL+ +SK     KR+   +D E+DVPL  RKK K       +KK       E+VE   K K S+ +   K +  SP K    KK+E++ EVWKWWEEEK +DGTKW FL+H+GP+FAP Y+ LP  V FYYN K+MKLS +TEEVA FYAR ++H+YT K  FN NFF DWR+VMT  ER  I++L+KC+F+E++TY+ + SEERK  +K+EK+  KE+N  IQ E+G C ID H EKIGNF+IEPPGLFRGR                  L+       + +  S  K  +IRH                 VK  +     K+K  K +  YE AR+L   I+KIR +Y  D+KSKEMR+RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLH  KDGK+Y V FDFLGKDSIRY+N VPVEKRVFKN+QLFMENK   DDLFDRLNTT++N++LN LM+GLTAKVFRT+NAS+TLQ QL++LT  DD +  K+LSYNRANR VAILCNHQR+ PKTH KSM+NL+ KI+AK+EA   AE  +K AK+  K+ GS  EKVV +KKKK L+R  EQL KLE QA DKEENK IALGTSKLNYLDPRISVAW KK DVPI+K+YNKTQRDKFRWAI+MAG DYVF
Sbjct:  374 IKTEEESDEDMPLSTRSKPNTTSKRRIYSDDEEEDVPLVVRKKSKKTETKAQIKKPKYEDEEEQVEQKPKKKRSRTS---KGDNTSPRK----KKQEEEQEVWKWWEEEKKNDGTKWTFLEHKGPVFAPSYEPLPPNVKFYYNGKEMKLSQDTEEVATFYARMLDHDYTTKPAFNSNFFHDWREVMTESERSKISDLNKCNFKEMHTYFLQKSEERKAMTKDEKQKIKEQNEEIQKEYGFCTIDGHKEKIGNFKIEPPGLFRGRGEHPKMGKLKKRVMPEDILINCSKDSCIPKPPSGHKWKEIRHDPNVTWLASWTENVQGQVKYVMLNPSSKLKGEKDWQKYETARKLAQSIDKIRAEYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKSPGDDLFDRLNTTVMNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTNPDDTIAEKILSYNRANRAVAILCNHQRSVPKTHAKSMENLKAKIEAKKEAITDAELAVKDAKREAKH-GSVKEKVVYEKKKKTLDRLREQLTKLEVQATDKEENKEIALGTSKLNYLDPRISVAWCKKNDVPIDKIYNKTQRDKFRWAIDMAGPDYVF 1029          

BLAST of EMLSAG00000000293 vs. nr
Match: gi|1134627525|ref|XP_019882816.1| (PREDICTED: DNA topoisomerase I, mitochondrial, partial [Camponotus floridanus])

HSP 1 Score: 720.309 bits (1858), Expect = 0.000e+0
Identity = 424/855 (49.59%), Postives = 548/855 (64.09%), Query Frame = 0

Query:  107 EEERKVRKEKERKEREERHKREGRRDE---TEDERRLRKERERKEREERHK-REGRREETEEERKARKEKEQRHKSKETEEERRVRKDKERAEKEARKRKEMGYDHSMGEEVSFHNHDEEMKMEQQEQQVKDEPQYEEELHEEQDEF--------EEDRYNNAKQENMEVE----------------VKVQDDSEDDIPLAKKSKNKKRKSR--DEDSEDDVPLSKRKKPKVKKV---------------ERVEVSKKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR-----------------------------------------------YLVGFMDRKYSKSNQIRHV----KSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            +++R + K+KER+ +  +H   G RD+   +       KE+ R   +++ K RE      +++ +  K+K++    K    + + ++DK++ E + ++  +M  +H+  E   FH ++ E+K E     +K+EP  + EL E+ D          EED    A +E   ++                +K ++DSE+D PL+ +SK      R  + D E+DVPLS RKKPK                   +  EV  + KS KK  + K E  SP K    +K+E++ EVWKWWEEEK  DGTKW FL+H+GP+FAP Y+ LP  V FYYN K+ KLS + EEVA FYAR ++H+YT K+ FN NFF DWR+VMT  ER  IT+LSKC+F+E++ Y+ + SEERK  +KEEK+  KEKN  IQ E+G CVID H EKIGNF+IEPPGLFRGR                                               +L  + +   +   Q+++V     S LK ++    YE AR+L   I+KIR +Y  D+KSKEMR+RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHI LH  +DGK+Y V FDFLGKDSIRY+N VPVEKRVFKN+QLFMENK   DDLFDRLNTT++N++LN LM+GLTAKVFRT+NAS+TLQ QL++LT+ +D    K+LSYNRANR VAILCNHQR+ PKTH KSM+NL+ KI AK+EA  + E  +K AK+  K+ GS  EKV  +KKKK LER  EQL KLE QA D+EENK IALGTSKLNYLDPRISVAW KK +VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct:  164 DKDRNLSKDKERENK--KHSSSGERDKDRHSTSHSSGDKEKHRSSEKDKDKHRESSSSSKDKQHRHEKDKDRHRHDKSKHRDEKEKRDKDKEEIKIKEETDMKLNHATNER--FH-YNLEVKPE-----IKEEPMTQLELDEDDDSGGERPLYIKEEDDDEEAVKEEASMDSTDGNDTRLSDLHNTTLKTEEDSEEDKPLSSRSKVSPSVKRKIESDEEEDVPLSARKKPKRATSSKTKKKKRKHDGENDDDSEVESEEKSKKKV-RAKGEGASPRK----RKQEEEQEVWKWWEEEKKSDGTKWHFLEHKGPVFAPPYEPLPPNVKFYYNGKETKLSQDAEEVATFYARMLDHDYTTKDAFNNNFFHDWREVMTESERAKITDLSKCNFKEMHAYFLQKSEERKAMTKEEKQKIKEKNDEIQKEYGFCVIDGHKEKIGNFKIEPPGLFRGRGEHPKMGKLKKRVLPEDVLINCSKDSNIPKPPAGHKWKEVRHDPNVTWLASWTE---NIQGQVKYVMLNPSSKLKGEKDWQKYETARKLAQSIDKIRAEYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHIKLHEQRDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKSPGDDLFDRLNTTVMNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTDPNDTEAEKILSYNRANRAVAILCNHQRSVPKTHAKSMENLKAKIDAKKEAIAECELQVKDAKRDAKH-GSVKEKVTYEKKKKQLERLKEQLTKLEVQATDREENKEIALGTSKLNYLDPRISVAWCKKHNVPIEKIYNKTQRDKFRWAIDMAGPDYVF 999          

BLAST of EMLSAG00000000293 vs. nr
Match: gi|913304894|ref|XP_013182884.1| (PREDICTED: DNA topoisomerase I, mitochondrial isoform X3 [Amyelois transitella])

HSP 1 Score: 720.309 bits (1858), Expect = 0.000e+0
Identity = 403/720 (55.97%), Postives = 493/720 (68.47%), Query Frame = 0

Query:  222 EMKMEQQEQQVKDEPQYEEELHEEQDEFEEDRYNNAKQENMEV--------------EVKVQDDSEDDIPLAKKSKNKKRKSRDEDSEDDVPLSKRKKPKVKKVERVEV-----------SKKSKSSKKNHKVKHE---VVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH----------------------VKSFLKIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            E  ++Q   QV DEP  + E+ EE     ED Y       M                E+  ++DSE+DIPL ++  +KKR +   +SE+D+PL +RKK K KKV++  +            KK    +K   +K E   VVSPTK   +KK+E++ EVWKWWEEEK DDGTKW FL+H+GPLFAP Y+ LP  V F Y+ K+++LS + EEVAGFYAR ++H+YT K+ FN NFF DWRKVMT+EE  +ITNLSKCDF+E+  Y+  VSE+ KNR+KEEK A K KN  IQ E+G C ID H EKIGNFRIEPPGLFRGR     +G + R+                       K  ++RH                      +    K+K  K +  YE AR+L   I+KIRD Y  D+K+KEMRVRQR+VALYFID+LALRAGNEKD+DQADTVGCCSLRVEHI LH  KDG+++ V FDFLGKDSIRY+N V VEKRVFKN++LFMENK+  DDLFDRLNT  LNE+L  LM GLTAKVFRT+NAS TLQ QL+ELT+A  ++P K+L+YNRANR VA+LCNHQRA PK H KSM+ L++KI+AKR+  E+AE+DLK A KA K  GS  EK++ DKKKKALER  EQL KLE Q  D++ENKTIALGTSKLNYLDPRISVAW KK  VPIEK+YNKTQRDKFRWAI+MAG +YVF
Sbjct:  238 ESSVKQDPIQV-DEPVVKNEIKEEP----EDGYGGFNNTTMSSCDYNLSQFKDEPLSELPQEEDSEEDIPLLERMASKKRPA--SESEEDIPLLQRKKLKKKKVKKEPIYDDEEDEEIKPKKKKIKPEKRKSIKQEPDEVVSPTKK--KKKQEEEQEVWKWWEEEKKDDGTKWTFLEHKGPLFAPPYEPLPSNVKFRYDGKEVRLSQDAEEVAGFYARMLDHDYTTKDTFNNNFFADWRKVMTKEETKLITNLSKCDFKEMQAYFLSVSEKNKNRTKEEKAALKAKNEEIQKEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGMLKRRVMPEDVLINCSKDSKIPKPPAGHKWKEVRHDNTVTWLASWTENVQGQSKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRDTYRNDWKAKEMRVRQRAVALYFIDRLALRAGNEKDDDQADTVGCCSLRVEHIELHKEKDGQEHVVVFDFLGKDSIRYYNEVAVEKRVFKNLELFMENKKDSDDLFDRLNTQTLNEHLKELMPGLTAKVFRTYNASITLQRQLDELTDAKASIPEKILAYNRANRAVAVLCNHQRAVPKGHSKSMEALKEKIQAKRDQVEEAERDLKDATKAAKR-GSEKEKIICDKKKKALERLKEQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHGVPIEKIYNKTQRDKFRWAIDMAGPEYVF 947          

BLAST of EMLSAG00000000293 vs. nr
Match: gi|646723372|gb|KDR24006.1| (DNA topoisomerase 1 [Zootermopsis nevadensis])

HSP 1 Score: 720.309 bits (1858), Expect = 0.000e+0
Identity = 400/706 (56.66%), Postives = 487/706 (68.98%), Query Frame = 0

Query:  227 QQEQQVKDEP-QYEEELHEEQDEFEEDRYNNAKQENMEVEVKVQDDSEDDIPL------------AKKSKNKKRKSRDEDSEDD-VPLSKRKKPKVKKVERVEVS-----KKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFM---------------DRKYSKSN------QIRHVKSFL----------------------KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            Q    +K+EP  + E L    +E  +    N K E    ++KV++D EDDIPL            A +S   + K R EDS+DD VPL  RKK K +  ++ E S     K  K   K   VK E+   +    +KK+E++ EVWKWWEEEK DDGTKWKFL+H+GP+FAP YDRLP  + F+Y+ K+M LS  TEEVA FYAR ++H+YT KE FN+NFFKDWRKVMT +E++ IT+LSKC+F++++ Y+   +EERK  SKEEKK  K++N  I  E+G CVID H E+IGNF+IEPPGLFRGR     +G +               D K  K        +IRH K+                        K+K  K +  YE AR+L   IEKIR +Y  DFKSKEMR+RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHI+LH+ KDGKDY V FDF GKDSIRY+N V VEKRVFKN+QLFM+NK   DDLFDRLNTT+LN++LN LM+GLTAKVFRT+NASFTLQ+QL++LT+ D  V  K+L+YNRANR VAILCNHQRA PKTH KSM+NL+ KI AK+E  + AE+  K  K  +K  GS   K+ M+K+KKALE+  EQL KLE QA DKEENK IAL TSKLNYLDPRISVAW KK +VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct:  256 QPMAWIKEEPVNHNERLVHSVNESGDQSSVNFKSETA-TKIKVEEDIEDDIPLWRSEDRAHRSGLASRSVVGEVKRRLEDSDDDDVPLMARKKIKKESKKQKEESDEEEFKPVKKKSKKGNVKEEITPQSSPRKKKKEEEQQEVWKWWEEEKKDDGTKWKFLEHKGPVFAPLYDRLPPDIKFFYDGKEMTLSEPTEEVASFYARMLDHDYTTKEAFNKNFFKDWRKVMTDKEKERITDLSKCNFKQMHKYFLAKAEERKAMSKEEKKKLKDQNEEIVKEYGFCVIDGHTERIGNFKIEPPGLFRGRGEHPKMGMLKKRVIPEDVIINCSKDSKIPKPPDGHKWREIRHDKNVTWLASWTENVQGQVKYVMLNPSSKLKGEKDWQKYETARKLAKCIEKIRQEYQDDFKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHISLHSQKDGKDYVVVFDFPGKDSIRYYNEVSVEKRVFKNLQLFMQNKSTGDDLFDRLNTTVLNKHLNELMEGLTAKVFRTYNASFTLQEQLDKLTDPDYTVQEKILAYNRANRAVAILCNHQRAVPKTHAKSMENLKGKIDAKKEMVQDAERQYKDVKHEHKRNGSAKNKIDMEKRKKALEKLREQLAKLELQATDKEENKEIALSTSKLNYLDPRISVAWCKKHNVPIEKIYNKTQRDKFRWAIDMAGPDYVF 960          

BLAST of EMLSAG00000000293 vs. nr
Match: gi|768417486|ref|XP_011549382.1| (PREDICTED: DNA topoisomerase I, mitochondrial [Plutella xylostella])

HSP 1 Score: 716.457 bits (1848), Expect = 0.000e+0
Identity = 385/655 (58.78%), Postives = 470/655 (71.76%), Query Frame = 0

Query:  271 DSEDDIPLAKKSKNKKRKSRDEDSEDDVPLSKRKKPKVKKVERV-----EVS------KKSKSSKKNHKVKHE-VVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDR---------------------KYSKSNQIRH----------------------VKSFLKIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            DSE+D PL ++   K+R  + E SEDD PL+ RKKPK KK+++      E+S      KK   +K   KVK E   SPTK   +KK++D+ EVWKWWEEEK DDGTKWKFL+H+GPLFAP Y+ +P+ V F Y+ K ++LS + EEVAGFYAR ++H+YT K VFN NFF DWRKVMT +E  +I +L KCDF+E+  Y++ VSE+ KNR+KEEK   K  N  IQ E+G C+ID H EKIGNFRIEPPGLFRGR     +G + +                     K  K  ++RH                      +    K+K  K +  YE AR+L   I+KIRD Y  D+K+KEMRVRQR+VALYFID+LALRAGNEKD+DQADTVGCCSLRVEHI LH  KDGK+Y V FDFLGKDSIRY+N VPVEKRVFKN++LFMENK+  DDLFDRLNT  LNE+L  LM GLTAKVFRT+NAS TLQ QL+ELT+ D ++P K+L+YNRANR VA+LCNHQRA PK HDKSM+ L++KI+AKR+  ++AE+D++Q+ KA K  GS  EK+  DKK KALER  +QL KLE Q  D++ENKTIALGTSKLNYLDPRISVAW KK DVPIEK+YNKTQRDKFRWAI+MAG +YVF
Sbjct:  293 DSEEDTPLLERMAPKRRAVKSE-SEDDTPLTMRKKPKKKKIKKESGYDEEMSDDEPKAKKPTKTKPAAKVKTEDGPSPTKR--KKKQDDEPEVWKWWEEEKKDDGTKWKFLEHKGPLFAPPYEPIPENVKFRYDGKVVRLSQDAEEVAGFYARMLDHDYTTKSVFNNNFFADWRKVMTHDEAKLIKDLKKCDFKEMQAYFQSVSEKNKNRTKEEKAQLKATNEEIQKEYGFCIIDGHKEKIGNFRIEPPGLFRGRGEHPKMGMLKKRVMPEDVLINCSKDSNVPKPPKGHKWKEVRHDNTVTWLASWTENVQGQTKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRDTYRSDWKAKEMRVRQRAVALYFIDRLALRAGNEKDDDQADTVGCCSLRVEHIALHKEKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLELFMENKKDSDDLFDRLNTQTLNEHLKELMPGLTAKVFRTYNASITLQRQLDELTDGDASIPEKILAYNRANRAVAVLCNHQRAVPKGHDKSMEALKEKIQAKRDQIDEAEEDVRQSAKAAKR-GSVKEKMNHDKKTKALERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIYNKTQRDKFRWAIDMAGPEYVF 943          

BLAST of EMLSAG00000000293 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold462_size163801-snap-gene-0.41 (protein:Tk04567 transcript:maker-scaffold462_size163801-snap-gene-0.41-mRNA-1 annotation:"topoisomerase 1b")

HSP 1 Score: 806.594 bits (2082), Expect = 0.000e+0
Identity = 424/691 (61.36%), Postives = 501/691 (72.50%), Query Frame = 0

Query:  247 DEFEEDRYNNAKQENMEVEVKVQDDSEDDIPLAKKSKNKK------RKSRDEDSEDDVPLSKRKKPK----------------VKKVERVEVSKKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEE--EKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYSK-----------------------------------------SNQIRHV----KSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
            D+  +D   + K+E M+ E     DSE+D PLA+ SK +K          D+D ++DVP++KRK+ K                VK  +  + +K  K +           +P + G + KKE+  EVWKWWEE   K DDGTKW+FL+H+GPLFAPDY+ LP  VHFYY  K+M+LS +TEEVA FY R ++H+YT KEVFNRN+ KDWRKVM  +E++II ++SKCDF+EI  ++KKVSEERK RSK+++KAEKE+N AIQ E+G C ID H EKIGNFRIEPP LFRGR      G + ++ S                                           NQI++V     S LK ++    YEKARELK  I KIRDDYT DFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLH  KDG++Y VEFDFLGKDSIRY+N VPVEKRVFKNVQLFMENK+  DDLFDRLNT+ILNEYLN+LM GLTAKVFRT+NAS TLQ+QL +LTE DDNVPAKMLSYNRANR VA+LCNHQRA PKTH+KSM NLQ KI+ K++A  KAEK+ K AKK++KNGGS + K+ MDKKKKALER +EQL+KLETQAVDKEENK+IALGTSKLNYLDPRISVAW KKFDVPIEKVYNKTQR+KFRWAIEMAG +Y F
Sbjct:  236 DDDSQDSQASMKEEPMDGE-----DSEEDKPLARNSKKRKVNDDEDEFQPDDDDDEDVPIAKRKRVKKEEPRYKEEDDDYQEDVKPAKSKKKAKPEKKTPSKPASSSASSNP-RGGKKVKKEENQEVWKWWEETTHKKDDGTKWQFLEHKGPLFAPDYEPLPSHVHFYYEGKRMRLSQDTEEVATFYGRMLDHDYTTKEVFNRNYMKDWRKVMNEKEKEIIRDISKCDFKEIGVHFKKVSEERKGRSKDDRKAEKERNEAIQKEYGFCTIDGHVEKIGNFRIEPPSLFRGRGEHPKQGMLKKRVSPEDVIINCSKNSDIPKPPEGRKWKKVQHDNTVTWLACWTENIQNQIKYVMLNPSSKLKGEKDMAKYEKARELKKLIHKIRDDYTADFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHPEKDGQEYVVEFDFLGKDSIRYNNCVPVEKRVFKNVQLFMENKKAGDDLFDRLNTSILNEYLNTLMPGLTAKVFRTYNASITLQEQLNQLTEEDDNVPAKMLSYNRANRAVAVLCNHQRAVPKTHEKSMTNLQTKIEGKKDAVNKAEKEFKAAKKSHKNGGSATSKINMDKKKKALERLMEQLNKLETQAVDKEENKSIALGTSKLNYLDPRISVAWCKKFDVPIEKVYNKTQREKFRWAIEMAGPEYQF 920