EMLSAG00000000293, EMLSAG00000000293-683059 (gene) Lepeophtheirus salmonis
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Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of EMLSAG00000000293 vs. GO
Match: - (symbol:TOP1 "Uncharacterized protein" species:9615 "Canis lupus familiaris" [GO:0000228 "nuclear chromosome" evidence=IEA] [GO:0000932 "cytoplasmic mRNA processing body" evidence=IEA] [GO:0003677 "DNA binding" evidence=IEA] [GO:0003682 "chromatin binding" evidence=IEA] [GO:0003917 "DNA topoisomerase type I activity" evidence=IEA] [GO:0003918 "DNA topoisomerase type II (ATP-hydrolyzing) activity" evidence=IEA] [GO:0005654 "nucleoplasm" evidence=IEA] [GO:0005730 "nucleolus" evidence=IEA] [GO:0006260 "DNA replication" evidence=IEA] [GO:0006265 "DNA topological change" evidence=IEA] [GO:0040016 "embryonic cleavage" evidence=IEA] [GO:0042493 "response to drug" evidence=IEA] [GO:0043204 "perikaryon" evidence=IEA] InterPro:IPR001631 InterPro:IPR008336 InterPro:IPR011010 InterPro:IPR013030 InterPro:IPR013034 InterPro:IPR013499 InterPro:IPR013500 InterPro:IPR014711 InterPro:IPR014727 InterPro:IPR018521 Pfam:PF01028 Pfam:PF02919 PRINTS:PR00416 PROSITE:PS00176 SMART:SM00435 GO:GO:0005654 GO:GO:0005730 GO:GO:0042493 GO:GO:0003677 GO:GO:0006260 GO:GO:0043204 GO:GO:0006200 GO:GO:0003682 GO:GO:0040016 GO:GO:0000932 GO:GO:0000228 GO:GO:0006265 SUPFAM:SSF56349 GO:GO:0003918 GO:GO:0003917 KO:K03163 OrthoDB:EOG7CVPX5 TreeFam:TF105281 Gene3D:1.10.10.41 Gene3D:1.10.132.10 Gene3D:2.170.11.10 Gene3D:3.90.15.10 InterPro:IPR025834 Pfam:PF14370 SUPFAM:SSF56741 GeneTree:ENSGT00390000016347 CTD:7150 OMA:EFDFPGK EMBL:AAEX03013937 EMBL:AAEX03013938 EMBL:AAEX03013939 RefSeq:XP_534420.3 Ensembl:ENSCAFT00000014397 GeneID:477229 KEGG:cfa:477229 Uniprot:F1PUE0) HSP 1 Score: 640.188 bits (1650), Expect = 0.000e+0 Identity = 332/553 (60.04%), Postives = 401/553 (72.51%), Query Frame = 0
Query: 362 DGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
+G KWKFL+H+GP+FAP Y+ LP+ V FYY+ K MKLS + EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT EE++IITNLSKCDF +++ Y+K SE RK SKEEK KE+N + E+G CV+DNH E+I NF+IEPPGLFRGR +G + R+ K ++RH +K + +IK K + YE AR LK ++KIR+ Y D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI LH DG++Y VEFDFLGKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT ILN++L LM+GLTAKVFRT+NAS TLQ QL+ELT D+N+PAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK+E A +DLK AK K K V++ KKKA++R EQL KLE QA D+EENK IALGTSKLNYLDPRI+VAW KK+ VPIEK+YNKTQR+KF WAI+MA DY F
Sbjct: 218 EGIKWKFLEHKGPVFAPPYEPLPESVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQSEARKQMSKEEKLKIKEENEKLLKEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPTGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKEQLADARRDLKSAKADAKVLKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF 770
BLAST of EMLSAG00000000293 vs. GO
Match: - (symbol:TOP1 "DNA topoisomerase 1" species:9606 "Homo sapiens" [GO:0000932 "cytoplasmic mRNA processing body" evidence=IDA] [GO:0003677 "DNA binding" evidence=IDA] [GO:0003682 "chromatin binding" evidence=IDA] [GO:0003917 "DNA topoisomerase type I activity" evidence=IMP;IDA] [GO:0003918 "DNA topoisomerase type II (ATP-hydrolyzing) activity" evidence=IEA] [GO:0005515 "protein binding" evidence=IPI] [GO:0005524 "ATP binding" evidence=IEA] [GO:0005634 "nucleus" evidence=IDA] [GO:0005654 "nucleoplasm" evidence=IDA] [GO:0005730 "nucleolus" evidence=IDA] [GO:0006260 "DNA replication" evidence=IBA] [GO:0006265 "DNA topological change" evidence=IDA;IBA] [GO:0006338 "chromatin remodeling" evidence=IBA] [GO:0007059 "chromosome segregation" evidence=IBA] [GO:0012501 "programmed cell death" evidence=NAS] [GO:0016032 "viral process" evidence=IEA] [GO:0016310 "phosphorylation" evidence=NAS] [GO:0031298 "replication fork protection complex" evidence=IBA] [GO:0040016 "embryonic cleavage" evidence=IEA] [GO:0042493 "response to drug" evidence=IEP] [GO:0043204 "perikaryon" evidence=IEA] [GO:0044822 "poly(A) RNA binding" evidence=IDA] [GO:0000228 "nuclear chromosome" evidence=IDA] InterPro:IPR001631 InterPro:IPR008336 InterPro:IPR011010 InterPro:IPR013030 InterPro:IPR013034 InterPro:IPR013499 InterPro:IPR013500 InterPro:IPR014711 InterPro:IPR014727 InterPro:IPR018521 Pfam:PF01028 Pfam:PF02919 PRINTS:PR00416 PROSITE:PS00176 SMART:SM00435 GO:GO:0005524 EMBL:CH471077 GO:GO:0016032 GO:GO:0007059 GO:GO:0005654 GO:GO:0005730 GO:GO:0042493 GO:GO:0003677 GO:GO:0006260 GO:GO:0043204 GO:GO:0006200 GO:GO:0003682 GO:GO:0040016 GO:GO:0000932 DrugBank:DB01030 GO:GO:0006338 GO:GO:0016310 GO:GO:0012501 DrugBank:DB04967 GO:GO:0031298 DrugBank:DB00762 GO:GO:0006265 SUPFAM:SSF56349 GO:GO:0003918 GO:GO:0003917 EMBL:AL022394 eggNOG:COG3569 HOVERGEN:HBG007988 KO:K03163 OrthoDB:EOG7CVPX5 TreeFam:TF105281 Gene3D:1.10.10.41 Gene3D:1.10.132.10 Gene3D:2.170.11.10 Gene3D:3.90.15.10 InterPro:IPR025834 Pfam:PF14370 SUPFAM:SSF56741 CTD:7150 ChiTaRS:TOP1 EMBL:J03250 EMBL:M60706 EMBL:M60688 EMBL:M60689 EMBL:M60690 EMBL:M60691 EMBL:M60692 EMBL:M60693 EMBL:M60694 EMBL:M60695 EMBL:M60696 EMBL:M60697 EMBL:M60698 EMBL:M60699 EMBL:M60700 EMBL:M60701 EMBL:M60702 EMBL:M60703 EMBL:M60704 EMBL:M60705 EMBL:AK292943 EMBL:AL035652 EMBL:X52601 EMBL:U07804 EMBL:U07806 EMBL:X16479 EMBL:M27913 PIR:A30887 RefSeq:NP_003277.1 UniGene:Hs.472737 PDB:1A31 PDB:1A35 PDB:1A36 PDB:1EJ9 PDB:1K4S PDB:1K4T PDB:1LPQ PDB:1NH3 PDB:1R49 PDB:1RR8 PDB:1RRJ PDB:1SC7 PDB:1SEU PDB:1T8I PDB:1TL8 PDBsum:1A31 PDBsum:1A35 PDBsum:1A36 PDBsum:1EJ9 PDBsum:1K4S PDBsum:1K4T PDBsum:1LPQ PDBsum:1NH3 PDBsum:1R49 PDBsum:1RR8 PDBsum:1RRJ PDBsum:1SC7 PDBsum:1SEU PDBsum:1T8I PDBsum:1TL8 DisProt:DP00075 ProteinModelPortal:P11387 SMR:P11387 BioGrid:113003 IntAct:P11387 MINT:MINT-94018 STRING:9606.ENSP00000354522 BindingDB:P11387 ChEMBL:CHEMBL1781 PhosphoSite:P11387 DMDM:12644118 SWISS-2DPAGE:P11387 PaxDb:P11387 PeptideAtlas:P11387 PRIDE:P11387 Ensembl:ENST00000361337 GeneID:7150 KEGG:hsa:7150 UCSC:uc002xjl.3 GeneCards:GC20P039657 H-InvDB:HIX0015818 H-InvDB:HIX0040702 HGNC:HGNC:11986 HPA:CAB009058 HPA:HPA019039 MIM:126420 neXtProt:NX_P11387 PharmGKB:PA353 InParanoid:P11387 OMA:EFDFPGK PhylomeDB:P11387 EvolutionaryTrace:P11387 GeneWiki:TOP1 GenomeRNAi:7150 NextBio:27982 PMAP-CutDB:P11387 PRO:PR:P11387 ArrayExpress:P11387 Bgee:P11387 CleanEx:HS_TOP1 Genevestigator:P11387 Uniprot:P11387) HSP 1 Score: 639.032 bits (1647), Expect = 0.000e+0 Identity = 330/553 (59.67%), Postives = 401/553 (72.51%), Query Frame = 0
Query: 362 DGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
+G KWKFL+H+GP+FAP Y+ LP+ V FYY+ K MKLS + EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT EE++IITNLSKCDF +++ Y+K +E RK SKEEK KE+N + E+G C++DNH E+I NF+IEPPGLFRGR +G + R+ K ++RH +K + +IK K + YE AR LK ++KIR+ Y D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI LH DG++Y VEFDFLGKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT ILN++L LM+GLTAKVFRT+NAS TLQ QL+ELT D+N+PAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK+E A +DLK AK K K V++ KKKA++R EQL KLE QA D+EENK IALGTSKLNYLDPRI+VAW KK+ VPIEK+YNKTQR+KF WAI+MA DY F
Sbjct: 213 EGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTKIDAKKEQLADARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF 765
BLAST of EMLSAG00000000293 vs. GO
Match: - (symbol:TOP1 "Uncharacterized protein" species:9823 "Sus scrofa" [GO:0003677 "DNA binding" evidence=IEA] [GO:0003917 "DNA topoisomerase type I activity" evidence=IEA] [GO:0003918 "DNA topoisomerase type II (ATP-hydrolyzing) activity" evidence=IEA] [GO:0005694 "chromosome" evidence=IEA] [GO:0006265 "DNA topological change" evidence=IEA] InterPro:IPR001631 InterPro:IPR008336 InterPro:IPR011010 InterPro:IPR013030 InterPro:IPR013034 InterPro:IPR013499 InterPro:IPR013500 InterPro:IPR014711 InterPro:IPR014727 InterPro:IPR018521 Pfam:PF01028 Pfam:PF02919 PRINTS:PR00416 PROSITE:PS00176 SMART:SM00435 GO:GO:0005694 GO:GO:0003677 GO:GO:0006200 GO:GO:0006265 SUPFAM:SSF56349 GO:GO:0003918 GO:GO:0003917 OrthoDB:EOG7CVPX5 Gene3D:1.10.10.41 Gene3D:1.10.132.10 Gene3D:2.170.11.10 Gene3D:3.90.15.10 InterPro:IPR025834 Pfam:PF14370 SUPFAM:SSF56741 GeneTree:ENSGT00390000016347 EMBL:CU062531 Ensembl:ENSSSCT00000008047 Uniprot:F1SDV7) HSP 1 Score: 639.032 bits (1647), Expect = 0.000e+0 Identity = 331/553 (59.86%), Postives = 401/553 (72.51%), Query Frame = 0
Query: 362 DGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
+G KWKFL+H+GP+FAP Y+ LP+ V FYY+ K MKLS + EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT EE++IITNLSKCDF +++ Y+K SE RK SKEEK KE+N + E+G C++DNH E+I NF+IEPPGLFRGR +G + R+ K ++RH +K + +IK K + YE AR LK ++KIR+ Y D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI LH DG++Y VEFDFLGKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT ILN++L LM+GLTAKVFRT+NAS TLQ QL+ELT D+N+PAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK+E A +DLK AK K K V++ KKKA++R EQL KLE QA D+EENK IALGTSKLNYLDPRI+VAW KK+ VPIEK+YNKTQR+KF WAI+MA DY F
Sbjct: 217 EGIKWKFLEHKGPVFAPPYEPLPESVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQSEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTKIDAKKEQLADARRDLKSAKADAKVLKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF 769
BLAST of EMLSAG00000000293 vs. GO
Match: - (symbol:TOP1 "DNA topoisomerase 1" species:9534 "Chlorocebus aethiops" [GO:0003677 "DNA binding" evidence=ISS] [GO:0003682 "chromatin binding" evidence=ISS] [GO:0003917 "DNA topoisomerase type I activity" evidence=ISS] [GO:0005634 "nucleus" evidence=ISS] [GO:0005654 "nucleoplasm" evidence=ISS] [GO:0005730 "nucleolus" evidence=ISS] [GO:0006265 "DNA topological change" evidence=ISS] [GO:0000228 "nuclear chromosome" evidence=ISS] InterPro:IPR001631 InterPro:IPR008336 InterPro:IPR011010 InterPro:IPR013030 InterPro:IPR013034 InterPro:IPR013499 InterPro:IPR013500 InterPro:IPR014711 InterPro:IPR014727 InterPro:IPR018521 Pfam:PF01028 Pfam:PF02919 PRINTS:PR00416 PROSITE:PS00176 SMART:SM00435 GO:GO:0005524 GO:GO:0005694 GO:GO:0005654 GO:GO:0005730 GO:GO:0003677 GO:GO:0006200 GO:GO:0003682 GO:GO:0006265 SUPFAM:SSF56349 GO:GO:0003918 GO:GO:0003917 HOVERGEN:HBG007988 Gene3D:1.10.10.41 Gene3D:1.10.132.10 Gene3D:2.170.11.10 Gene3D:3.90.15.10 InterPro:IPR025834 Pfam:PF14370 SUPFAM:SSF56741 EMBL:AB089321 ProteinModelPortal:Q7YR26 SMR:Q7YR26 BindingDB:Q7YR26 ChEMBL:CHEMBL5265 PRIDE:Q7YR26 Uniprot:Q7YR26) HSP 1 Score: 638.262 bits (1645), Expect = 0.000e+0 Identity = 330/552 (59.78%), Postives = 399/552 (72.28%), Query Frame = 0
Query: 363 GTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
G KWKFL+H+GP+FAP Y+ LP V FYY+ K MKLS + EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT EE++IITNLSKCDF +++ Y+K +E RK SKEEK KE+N + E+G C++DNH E+I NF+IEPPGLFRGR +G + R+ K ++RH +K + +IK K + YE AR LK ++KIR+ Y D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI LH DG++Y VEFDFLGKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT ILN++L LM+GLTAKVFRT+NAS TLQ QL+ELT D+N+PAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK+E A +DLK AK K K V++ KKKA++R EQL KLE QA D+EENK IALGTSKLNYLDPRI+VAW KK+ VPIEK+YNKTQR+KF WAI+MA DY F
Sbjct: 216 GIKWKFLEHKGPVFAPPYEPLPDSVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKEQLADARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF 767
BLAST of EMLSAG00000000293 vs. GO
Match: - (symbol:TOP1 "Uncharacterized protein" species:9913 "Bos taurus" [GO:0000228 "nuclear chromosome" evidence=IEA] [GO:0000932 "cytoplasmic mRNA processing body" evidence=IEA] [GO:0003677 "DNA binding" evidence=IEA] [GO:0003682 "chromatin binding" evidence=IEA] [GO:0003917 "DNA topoisomerase type I activity" evidence=IEA] [GO:0003918 "DNA topoisomerase type II (ATP-hydrolyzing) activity" evidence=IEA] [GO:0005654 "nucleoplasm" evidence=IEA] [GO:0005730 "nucleolus" evidence=IEA] [GO:0006260 "DNA replication" evidence=IEA] [GO:0006265 "DNA topological change" evidence=IEA] [GO:0040016 "embryonic cleavage" evidence=IEA] [GO:0042493 "response to drug" evidence=IEA] [GO:0043204 "perikaryon" evidence=IEA] InterPro:IPR001631 InterPro:IPR008336 InterPro:IPR011010 InterPro:IPR013030 InterPro:IPR013034 InterPro:IPR013499 InterPro:IPR013500 InterPro:IPR014711 InterPro:IPR014727 InterPro:IPR018521 Pfam:PF01028 Pfam:PF02919 PRINTS:PR00416 PROSITE:PS00176 SMART:SM00435 GO:GO:0005654 GO:GO:0005730 GO:GO:0042493 GO:GO:0003677 GO:GO:0006260 GO:GO:0043204 GO:GO:0006200 GO:GO:0003682 GO:GO:0040016 GO:GO:0000932 GO:GO:0000228 GO:GO:0006265 SUPFAM:SSF56349 GO:GO:0003918 GO:GO:0003917 KO:K03163 OrthoDB:EOG7CVPX5 TreeFam:TF105281 Gene3D:1.10.10.41 Gene3D:1.10.132.10 Gene3D:2.170.11.10 Gene3D:3.90.15.10 InterPro:IPR025834 Pfam:PF14370 SUPFAM:SSF56741 GeneTree:ENSGT00390000016347 CTD:7150 OMA:EFDFPGK EMBL:DAAA02036643 EMBL:DAAA02036644 RefSeq:NP_001193416.1 UniGene:Bt.39255 PRIDE:F1MN93 Ensembl:ENSBTAT00000010466 GeneID:534799 KEGG:bta:534799 NextBio:20876536 ArrayExpress:F1MN93 Uniprot:F1MN93) HSP 1 Score: 637.876 bits (1644), Expect = 0.000e+0 Identity = 331/553 (59.86%), Postives = 401/553 (72.51%), Query Frame = 0
Query: 362 DGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
+G KWKFL+H+GP+FAP Y+ LP+ V FYY+ K MKLS + EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT EE++IITNLSKCDF +++ Y+K +E RK SKEEK KE+N + E+G CV+DNH E+I NF+IEPPGLFRGR +G + R+ K ++RH +K + +IK K + YE AR LK ++KIR+ Y D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI LH DG++Y VEFDFLGKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT ILN++L LM+GLTAKVFRT+NAS TLQ QL+ELT D+N+PAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK+E A +DLK AK K K V++ KKKA++R EQL KLE QA D+EENK IALGTSKLNYLDPRI+VAW KK+ VPIEK+YNKTQR+KF WAI+MA DY F
Sbjct: 217 EGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKEQLADARRDLKSAKADAKVLKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF 769
BLAST of EMLSAG00000000293 vs. GO
Match: - (symbol:Top1 "DNA topoisomerase 1" species:10116 "Rattus norvegicus" [GO:0003918 "DNA topoisomerase type II (ATP-hydrolyzing) activity" evidence=IEA] [GO:0005524 "ATP binding" evidence=IEA] [GO:0005654 "nucleoplasm" evidence=IEA] [GO:0005730 "nucleolus" evidence=IEA] [GO:0006260 "DNA replication" evidence=IBA] [GO:0006338 "chromatin remodeling" evidence=IBA] [GO:0007059 "chromosome segregation" evidence=IBA] [GO:0031298 "replication fork protection complex" evidence=IBA] InterPro:IPR001631 InterPro:IPR008336 InterPro:IPR011010 InterPro:IPR013030 InterPro:IPR013034 InterPro:IPR013499 InterPro:IPR013500 InterPro:IPR014711 InterPro:IPR014727 InterPro:IPR018521 Pfam:PF01028 Pfam:PF02919 PRINTS:PR00416 PROSITE:PS00176 SMART:SM00435 RGD:621246 GO:GO:0005524 GO:GO:0007059 GO:GO:0005654 GO:GO:0005730 GO:GO:0032403 GO:GO:0071373 GO:GO:0006260 GO:GO:0031100 GO:GO:0006200 GO:GO:0010332 GO:GO:0006338 GO:GO:0051591 GO:GO:0009303 GO:GO:0031490 GO:GO:0009266 GO:GO:0031298 GO:GO:0006265 SUPFAM:SSF56349 GO:GO:0003918 GO:GO:0003917 eggNOG:COG3569 HOGENOM:HOG000105469 HOVERGEN:HBG007988 KO:K03163 TreeFam:TF105281 Gene3D:1.10.10.41 Gene3D:1.10.132.10 Gene3D:2.170.11.10 Gene3D:3.90.15.10 InterPro:IPR025834 Pfam:PF14370 SUPFAM:SSF56741 CTD:7150 EMBL:AF140782 RefSeq:NP_072137.1 UniGene:Rn.91572 ProteinModelPortal:Q9WUL0 SMR:Q9WUL0 BioGrid:249131 IntAct:Q9WUL0 BindingDB:Q9WUL0 ChEMBL:CHEMBL1075164 PhosphoSite:Q9WUL0 PaxDb:Q9WUL0 PRIDE:Q9WUL0 GeneID:64550 KEGG:rno:64550 UCSC:RGD:621246 NextBio:613440 PRO:PR:Q9WUL0 Genevestigator:Q9WUL0 Uniprot:Q9WUL0) HSP 1 Score: 634.795 bits (1636), Expect = 0.000e+0 Identity = 330/552 (59.78%), Postives = 398/552 (72.10%), Query Frame = 0
Query: 363 GTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
G KWKFL+H+GP+FAP Y+ LP+GV FYY+ K MKLS + EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT +E++ ITNLSKCDF +++ Y+K SE RK SKEEK KE+N + E+G CV+DNH E+I NF+IEPPGLFRGR +G + R+ K ++RH +K + +IK K + YE AR LK ++KIR+ Y D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI LH DG++Y VEFDF GKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT ILN++L LM+GLTAKVFRT+NAS TLQ QL+ELT D+NVPAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK++ A KDLK AK K K V++ KKKA++R EQL KLE QA D+EENK IALGTSKLNYLDPRI+VAW KK+ VPIEK+YNKTQR+KF WAI+M DY F
Sbjct: 216 GIKWKFLEHKGPVFAPPYEPLPEGVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNDEKNTITNLSKCDFTQMSQYFKAQSEARKQMSKEEKLKIKEENEKLLKEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARKDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 767
BLAST of EMLSAG00000000293 vs. GO
Match: - (symbol:Top1 "topoisomerase (DNA) I" species:10116 "Rattus norvegicus" [GO:0000932 "cytoplasmic mRNA processing body" evidence=ISO] [GO:0001651 "dense fibrillar component" evidence=IDA] [GO:0003677 "DNA binding" evidence=ISO;IDA] [GO:0003682 "chromatin binding" evidence=ISO] [GO:0003917 "DNA topoisomerase type I activity" evidence=ISO;IDA] [GO:0003918 "DNA topoisomerase type II (ATP-hydrolyzing) activity" evidence=IEA] [GO:0005524 "ATP binding" evidence=IEA] [GO:0005634 "nucleus" evidence=ISO;IDA] [GO:0005654 "nucleoplasm" evidence=IEA;ISO] [GO:0005730 "nucleolus" evidence=IEA;ISO] [GO:0005737 "cytoplasm" evidence=ISO] [GO:0006260 "DNA replication" evidence=ISO;IBA] [GO:0006265 "DNA topological change" evidence=ISO;IDA] [GO:0006338 "chromatin remodeling" evidence=IBA] [GO:0007059 "chromosome segregation" evidence=IBA] [GO:0009266 "response to temperature stimulus" evidence=IEP] [GO:0009303 "rRNA transcription" evidence=IMP] [GO:0010332 "response to gamma radiation" evidence=IEP] [GO:0031100 "organ regeneration" evidence=IEP] [GO:0031298 "replication fork protection complex" evidence=IBA] [GO:0031490 "chromatin DNA binding" evidence=IDA] [GO:0032403 "protein complex binding" evidence=IDA] [GO:0040016 "embryonic cleavage" evidence=ISO] [GO:0042493 "response to drug" evidence=ISO] [GO:0043204 "perikaryon" evidence=ISO] [GO:0044822 "poly(A) RNA binding" evidence=ISO] [GO:0051591 "response to cAMP" evidence=IEP] [GO:0071373 "cellular response to luteinizing hormone stimulus" evidence=IEP] [GO:0000228 "nuclear chromosome" evidence=ISO] InterPro:IPR001631 InterPro:IPR008336 InterPro:IPR011010 InterPro:IPR013030 InterPro:IPR013034 InterPro:IPR013499 InterPro:IPR013500 InterPro:IPR014711 InterPro:IPR014727 InterPro:IPR018521 Pfam:PF01028 Pfam:PF02919 PRINTS:PR00416 PROSITE:PS00176 SMART:SM00435 RGD:621246 GO:GO:0005524 GO:GO:0007059 GO:GO:0005654 GO:GO:0005730 GO:GO:0032403 GO:GO:0071373 GO:GO:0006260 GO:GO:0031100 GO:GO:0006200 GO:GO:0010332 GO:GO:0006338 GO:GO:0051591 GO:GO:0009303 GO:GO:0031490 GO:GO:0009266 GO:GO:0031298 GO:GO:0006265 SUPFAM:SSF56349 GO:GO:0003918 GO:GO:0003917 eggNOG:COG3569 HOGENOM:HOG000105469 HOVERGEN:HBG007988 KO:K03163 TreeFam:TF105281 Gene3D:1.10.10.41 Gene3D:1.10.132.10 Gene3D:2.170.11.10 Gene3D:3.90.15.10 InterPro:IPR025834 Pfam:PF14370 SUPFAM:SSF56741 CTD:7150 EMBL:AF140782 RefSeq:NP_072137.1 UniGene:Rn.91572 ProteinModelPortal:Q9WUL0 SMR:Q9WUL0 BioGrid:249131 IntAct:Q9WUL0 BindingDB:Q9WUL0 ChEMBL:CHEMBL1075164 PhosphoSite:Q9WUL0 PaxDb:Q9WUL0 PRIDE:Q9WUL0 GeneID:64550 KEGG:rno:64550 UCSC:RGD:621246 NextBio:613440 PRO:PR:Q9WUL0 Genevestigator:Q9WUL0 Uniprot:Q9WUL0) HSP 1 Score: 634.795 bits (1636), Expect = 0.000e+0 Identity = 330/552 (59.78%), Postives = 398/552 (72.10%), Query Frame = 0
Query: 363 GTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
G KWKFL+H+GP+FAP Y+ LP+GV FYY+ K MKLS + EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT +E++ ITNLSKCDF +++ Y+K SE RK SKEEK KE+N + E+G CV+DNH E+I NF+IEPPGLFRGR +G + R+ K ++RH +K + +IK K + YE AR LK ++KIR+ Y D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI LH DG++Y VEFDF GKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT ILN++L LM+GLTAKVFRT+NAS TLQ QL+ELT D+NVPAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK++ A KDLK AK K K V++ KKKA++R EQL KLE QA D+EENK IALGTSKLNYLDPRI+VAW KK+ VPIEK+YNKTQR+KF WAI+M DY F
Sbjct: 216 GIKWKFLEHKGPVFAPPYEPLPEGVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNDEKNTITNLSKCDFTQMSQYFKAQSEARKQMSKEEKLKIKEENEKLLKEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARKDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 767
BLAST of EMLSAG00000000293 vs. GO
Match: - (symbol:top1alpha "Topoisomerase I alpha" species:31033 "Takifugu rubripes" [GO:0003917 "DNA topoisomerase type I activity" evidence=IBA] [GO:0005730 "nucleolus" evidence=IBA] [GO:0006260 "DNA replication" evidence=IBA] [GO:0006265 "DNA topological change" evidence=IBA] [GO:0006338 "chromatin remodeling" evidence=IBA] [GO:0007059 "chromosome segregation" evidence=IBA] [GO:0031298 "replication fork protection complex" evidence=IBA] InterPro:IPR001631 InterPro:IPR008336 InterPro:IPR011010 InterPro:IPR013030 InterPro:IPR013034 InterPro:IPR013499 InterPro:IPR013500 InterPro:IPR014711 InterPro:IPR014727 InterPro:IPR018521 Pfam:PF01028 Pfam:PF02919 PRINTS:PR00416 PROSITE:PS00176 SMART:SM00435 GO:GO:0007059 GO:GO:0005730 GO:GO:0003677 GO:GO:0006260 GO:GO:0006200 GO:GO:0006338 GO:GO:0031298 GO:GO:0006265 SUPFAM:SSF56349 GO:GO:0003918 GO:GO:0003917 eggNOG:COG3569 HOGENOM:HOG000105469 Gene3D:1.10.10.41 Gene3D:1.10.132.10 Gene3D:2.170.11.10 Gene3D:3.90.15.10 InterPro:IPR025834 Pfam:PF14370 SUPFAM:SSF56741 EMBL:AL035357 ProteinModelPortal:Q90WS0 SMR:Q90WS0 STRING:31033.ENSTRUP00000001370 Uniprot:Q90WS0) HSP 1 Score: 633.254 bits (1632), Expect = 0.000e+0 Identity = 320/553 (57.87%), Postives = 398/553 (71.97%), Query Frame = 0
Query: 362 DGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKY---------------------SKSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
DG+KW+FL+H+GP+FAP Y+ LP V FYY+ K MKL++ EEVA F+A+ ++HEYT K+VF +NFFKDWRK MT EE+ IT+L+KC+F +N Y+K SE RK SKEEK+ KE N I E+G C++DNH E+IGNFRIEPPGLFRGR +G + R+ +K ++RH +K + +IK K + YE AR LK +++IR+ Y D+KSKEMR+RQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI L+ D ++Y VEFDFLGKDSIRY+N +PVEKRVFKN+QLF+ENK+ DDLFDRLNT+ILN++L LM GLTAKVFRT+NAS TLQ QL+EL+ +DD+VPAK+LSYNRANR VAILCNHQRA PKT +KSMQNLQ KI K++ A K LK AK +K K ++ K+KA++R EQL KL+ QA D+EENK IALGTSKLNYLDPRISVAW KKF +PIEK+YNKTQR+KF WAI+MA D+ F
Sbjct: 215 DGSKWRFLEHKGPVFAPPYEPLPDKVKFYYDGKLMKLAAPAEEVATFFAKMLDHEYTTKDVFRKNFFKDWRKEMTSEEKSKITDLNKCNFAGMNDYFKAQSEARKQMSKEEKQKIKEDNERILQEYGFCIMDNHKERIGNFRIEPPGLFRGRGDHPKMGMLKRRIRPEDIIINCSKDSKHPKPPPGTKWKEVRHDNKVTWLASWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDRIRNQYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLYPKLDDQEYVVEFDFLGKDSIRYYNRIPVEKRVFKNLQLFLENKQPGDDLFDRLNTSILNKHLQELMDGLTAKVFRTYNASITLQQQLKELSCSDDSVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMQNLQTKIDEKQKQLSAARKQLKAAKAEHKASHDDKSKKAVEVKRKAVQRIEEQLMKLQVQATDREENKQIALGTSKLNYLDPRISVAWCKKFGIPIEKIYNKTQREKFAWAIDMAEKDFEF 767
BLAST of EMLSAG00000000293 vs. GO
Match: - (symbol:TOP1 "DNA topoisomerase 1" species:10029 "Cricetulus griseus" [GO:0003677 "DNA binding" evidence=ISS] [GO:0003682 "chromatin binding" evidence=ISS] [GO:0003917 "DNA topoisomerase type I activity" evidence=ISS] [GO:0005634 "nucleus" evidence=ISS] [GO:0005654 "nucleoplasm" evidence=ISS] [GO:0005730 "nucleolus" evidence=ISS] [GO:0006265 "DNA topological change" evidence=ISS] [GO:0000228 "nuclear chromosome" evidence=ISS] InterPro:IPR001631 InterPro:IPR008336 InterPro:IPR011010 InterPro:IPR013030 InterPro:IPR013034 InterPro:IPR013499 InterPro:IPR013500 InterPro:IPR014711 InterPro:IPR014727 InterPro:IPR018521 Pfam:PF01028 Pfam:PF02919 PRINTS:PR00416 PROSITE:PS00176 SMART:SM00435 GO:GO:0005524 GO:GO:0005694 GO:GO:0005654 GO:GO:0005730 GO:GO:0003677 GO:GO:0006200 GO:GO:0003682 GO:GO:0006265 SUPFAM:SSF56349 GO:GO:0003918 GO:GO:0003917 HOVERGEN:HBG007988 KO:K03163 Gene3D:1.10.10.41 Gene3D:1.10.132.10 Gene3D:2.170.11.10 Gene3D:3.90.15.10 InterPro:IPR025834 Pfam:PF14370 SUPFAM:SSF56741 EMBL:Z21624 EMBL:Z21625 PIR:A49546 RefSeq:NP_001230963.1 ProteinModelPortal:Q07050 SMR:Q07050 PRIDE:Q07050 GeneID:100689046 KEGG:cge:100689046 CTD:7150 Uniprot:Q07050) HSP 1 Score: 632.484 bits (1630), Expect = 0.000e+0 Identity = 328/552 (59.42%), Postives = 398/552 (72.10%), Query Frame = 0
Query: 363 GTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
G KWKFL+H+GP+FAP Y+ LP+GV FYY+ K MKLS + EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT +E+++ITNLSKCDF +++ Y+K SE RK SKEEK KE+N + E+G CV+DNH E+I NF+IEPPGLFRGR +G + R+ K ++RH +K + +IK K + YE AR LK ++KIR+ Y D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTV CCSLRVEHI LH DG++Y VEFDF GKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT ILN++L LM+GLTAKVFRT+NAS TLQ QL+ELT D+NVPAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK++ A +DLK AK K K V++ KKKA++R EQL KLE QA D+EENK IALGTSKLNYLDPRI+VAW KK+ VPIEK+YNKTQR+KF WAI+M DY F
Sbjct: 216 GIKWKFLEHKGPVFAPPYEPLPEGVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNDEKNVITNLSKCDFTQMSQYFKDQSEARKQMSKEEKLKIKEENEKLLKEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVSCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 767
BLAST of EMLSAG00000000293 vs. GO
Match: - (symbol:Top1 "topoisomerase (DNA) I" species:10090 "Mus musculus" [GO:0000166 "nucleotide binding" evidence=IEA] [GO:0000228 "nuclear chromosome" evidence=ISO] [GO:0000932 "cytoplasmic mRNA processing body" evidence=ISO] [GO:0001651 "dense fibrillar component" evidence=ISO] [GO:0003677 "DNA binding" evidence=ISO] [GO:0003682 "chromatin binding" evidence=ISO] [GO:0003916 "DNA topoisomerase activity" evidence=IEA] [GO:0003917 "DNA topoisomerase type I activity" evidence=ISO;IDA] [GO:0003918 "DNA topoisomerase type II (ATP-hydrolyzing) activity" evidence=IEA] [GO:0005524 "ATP binding" evidence=IEA] [GO:0005634 "nucleus" evidence=ISO;IDA] [GO:0005654 "nucleoplasm" evidence=ISO] [GO:0005694 "chromosome" evidence=IEA] [GO:0005730 "nucleolus" evidence=ISO;IBA] [GO:0005737 "cytoplasm" evidence=IDA] [GO:0006260 "DNA replication" evidence=IMP] [GO:0006265 "DNA topological change" evidence=ISO;IDA] [GO:0006338 "chromatin remodeling" evidence=IBA] [GO:0007059 "chromosome segregation" evidence=IBA] [GO:0009303 "rRNA transcription" evidence=ISO] [GO:0016853 "isomerase activity" evidence=IEA] [GO:0031298 "replication fork protection complex" evidence=IBA] [GO:0031490 "chromatin DNA binding" evidence=ISO] [GO:0032403 "protein complex binding" evidence=ISO] [GO:0040016 "embryonic cleavage" evidence=IMP] [GO:0043204 "perikaryon" evidence=IDA] [GO:0044822 "poly(A) RNA binding" evidence=ISO] InterPro:IPR001631 InterPro:IPR008336 InterPro:IPR011010 InterPro:IPR013030 InterPro:IPR013034 InterPro:IPR013499 InterPro:IPR013500 InterPro:IPR014711 InterPro:IPR014727 InterPro:IPR018521 Pfam:PF01028 Pfam:PF02919 PRINTS:PR00416 PROSITE:PS00176 SMART:SM00435 MGI:MGI:98788 GO:GO:0005524 GO:GO:0005737 GO:GO:0007059 GO:GO:0005654 GO:GO:0005730 GO:GO:0042493 GO:GO:0003677 GO:GO:0006260 GO:GO:0043204 GO:GO:0006200 GO:GO:0003682 GO:GO:0040016 GO:GO:0000932 GO:GO:0006338 GO:GO:0031298 GO:GO:0006265 SUPFAM:SSF56349 GO:GO:0003918 GO:GO:0003917 eggNOG:COG3569 HOGENOM:HOG000105469 HOVERGEN:HBG007988 KO:K03163 OrthoDB:EOG7CVPX5 TreeFam:TF105281 Gene3D:1.10.10.41 Gene3D:1.10.132.10 Gene3D:2.170.11.10 Gene3D:3.90.15.10 InterPro:IPR025834 Pfam:PF14370 SUPFAM:SSF56741 GeneTree:ENSGT00390000016347 CTD:7150 ChiTaRS:TOP1 OMA:EFDFPGK EMBL:D10061 EMBL:L20632 EMBL:AL590414 EMBL:AL591673 PIR:JU0144 RefSeq:NP_033434.2 UniGene:Mm.217233 ProteinModelPortal:Q04750 SMR:Q04750 BioGrid:204275 IntAct:Q04750 MINT:MINT-1868161 BindingDB:Q04750 ChEMBL:CHEMBL2814 PhosphoSite:Q04750 PaxDb:Q04750 PRIDE:Q04750 Ensembl:ENSMUST00000109468 GeneID:21969 KEGG:mmu:21969 UCSC:uc008nqy.1 InParanoid:Q04750 NextBio:301666 PMAP-CutDB:Q04750 PRO:PR:Q04750 ArrayExpress:Q04750 Bgee:Q04750 CleanEx:MM_TOP1 Genevestigator:Q04750 Uniprot:Q04750) HSP 1 Score: 631.713 bits (1628), Expect = 0.000e+0 Identity = 328/552 (59.42%), Postives = 397/552 (71.92%), Query Frame = 0
Query: 363 GTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
G KWKFL+H+GP+FAP Y+ LP+ V FYY+ K MKLS + EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT +E++ ITNLSKCDF +++ Y+K SE RK SKEEK KE+N + E+G CV+DNH E+I NF+IEPPGLFRGR +G + R+ K ++RH +K + +IK K + YE AR LK ++KIR+ Y D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI LH DG++Y VEFDF GKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT ILN++L LM+GLTAKVFRT+NAS TLQ QL+ELT D+NVPAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK++ A +DLK AK K K V++ KKKA++R EQL KLE QA D+EENK IALGTSKLNYLDPRI+VAW KK+ VPIEK+YNKTQR+KF WAI+M DY F
Sbjct: 216 GIKWKFLEHKGPVFAPPYEPLPESVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNDEKNTITNLSKCDFTQMSQYFKAQSEARKQMSKEEKLKIKEENEKLLKEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 767
BLAST of EMLSAG00000000293 vs. C. finmarchicus
Match: gi|592776306|gb|GAXK01178262.1| (TSA: Calanus finmarchicus comp15061_c1_seq1 transcribed RNA sequence) HSP 1 Score: 619.002 bits (1595), Expect = 0.000e+0 Identity = 359/548 (65.51%), Postives = 414/548 (75.55%), Query Frame = 0
Query: 363 GTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYXXXXXXXXXXXXXXXXXXXXXXXAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---------------------------YLVGFMDRKYSK-----------------SNQIRHV----KSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDXXXXXXXXXXXXXXXXXXXXXXYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGAD 862
G KWKFLQH GP FAPDYD LP+ V F+Y K ++L+ ETEE A FY R ++H+YT KEVFN+NFFKDWRKVMT +E+DII +LSKCDF EIN ++KKVSEERKNRSKEEKKAEKE N AI +FG C +D H EKIGNFR EPP LFRGR V RK+ K QI+++ S LK ++ YEKAR+LK +I KIRDDY D KSKEMRVRQR+VALYFID+LALRAGNEKDEDQADTVGCCSLRVEHI LH DGK++ VEFDFLGKDSIRYHN VEK+V+KNV+LFMENK+ DDLFDRLNT++LN+YLNSLM GLTAKVFRT+NASFTLQ+QL+E+T+ +DNV AKMLSYNRANR VA+LCNHQRA PKTH+KSM NL KI+AK++A ++AEK LK AKKAYKN GS +EK +KKKK LER +EQL+KLE Q DK+ENKTIALGTSKLNYLDPRISVAW KK DVPIEKVYNKTQR+KFRWAI+M D
Sbjct: 1523 GVKWKFLQHLGPQFAPDYDPLPEHVRFWYEGKTLRLTEETEECATFYGRMLDHDYTTKEVFNKNFFKDWRKVMTEKEKDIIRDLSKCDFSEINEHFKKVSEERKNRSKEEKKAEKEVNEAIIADFGFCTMDGHQEKIGNFRTEPPSLFRGRGEHPKQGMIKRRIMPEDVIINCSKDSEIPVPPKGRKWKKVQHDNTVTWLASWTENIQGQIKYIMLNPSSRLKGEKDWQKYEKARKLKVEIHKIRDDYMEDMKSKEMRVRQRAVALYFIDRLALRAGNEKDEDQADTVGCCSLRVEHIELHEQLDGKEFVVEFDFLGKDSIRYHNTTSVEKKVYKNVKLFMENKKDGDDLFDRLNTSVLNQYLNSLMDGLTAKVFRTYNASFTLQEQLDEMTDPNDNVSAKMLSYNRANRAVAVLCNHQRAVPKTHEKSMDNLYGKIEAKQDAIKEAEKGLKHAKKAYKNNGSVAEKANAEKKKKTLERLLEQLEKLEIQKTDKDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKVYNKTQREKFRWAIDMITND 3166
BLAST of EMLSAG00000000293 vs. C. finmarchicus
Match: gi|592810838|gb|GAXK01143730.1| (TSA: Calanus finmarchicus comp3642341_c0_seq1 transcribed RNA sequence) HSP 1 Score: 35.8094 bits (81), Expect = 5.175e-1 Identity = 23/51 (45.10%), Postives = 37/51 (72.55%), Query Frame = 0
Query: 778 TSEKVVMDKKKKALERTVEQL-DKLETQAVDKEENKTIALGTSKLNYLDPR 827
++EK +M++K K LE E L +KLET+ ++KEE+K+++ +LN LDPR
Sbjct: 560 SNEKEIMEEKLKDLETENEILREKLETKEIEKEESKSLS---EELNILDPR 703
BLAST of EMLSAG00000000293 vs. C. finmarchicus
Match: gi|592938100|gb|GAXK01020453.1| (TSA: Calanus finmarchicus comp12086_c0_seq4 transcribed RNA sequence) HSP 1 Score: 35.039 bits (79), Expect = 1.346e+0 Identity = 24/87 (27.59%), Postives = 44/87 (50.57%), Query Frame = 0
Query: 780 EKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVA---WSKKFDVPIEKVYNKTQRDKFRWAIEMAGADY 863
E+ +++++ L + E+ +LETQ + N A G+S ++PRI + W + V ++ ++QR R EMAG D+
Sbjct: 2196 ERSELERREAILAKNREREGRLETQRKNSRGNIEFAFGSSAPRLIEPRIDSSSGYWGSR-SVTGPGMFERSQRSMDR---EMAGGDF 2444
BLAST of EMLSAG00000000293 vs. C. finmarchicus
Match: gi|592938102|gb|GAXK01020451.1| (TSA: Calanus finmarchicus comp12086_c0_seq2 transcribed RNA sequence) HSP 1 Score: 35.039 bits (79), Expect = 1.361e+0 Identity = 24/87 (27.59%), Postives = 44/87 (50.57%), Query Frame = 0
Query: 780 EKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVA---WSKKFDVPIEKVYNKTQRDKFRWAIEMAGADY 863
E+ +++++ L + E+ +LETQ + N A G+S ++PRI + W + V ++ ++QR R EMAG D+
Sbjct: 2615 ERSELERREAILAKNREREGRLETQRKNSRGNIEFAFGSSAPRLIEPRIDSSSGYWGSR-SVTGPGMFERSQRSMDR---EMAGGDF 2863
BLAST of EMLSAG00000000293 vs. C. finmarchicus
Match: gi|592938101|gb|GAXK01020452.1| (TSA: Calanus finmarchicus comp12086_c0_seq3 transcribed RNA sequence) HSP 1 Score: 33.113 bits (74), Expect = 5.935e+0 Identity = 23/92 (25.00%), Postives = 43/92 (46.74%), Query Frame = 0
Query: 780 EKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVA---WSKKFDVPIEKVYNKT-----QRDKFRWAIEMAGADY 863
E+ +++++ L + E+ +LETQ + N A G+S ++PRI + W + V++ T +R + EMAG D+
Sbjct: 2196 ERSELERREAILAKNREREGRLETQRKNSRGNIEFAFGSSAPRLIEPRIDSSSGYWGSRRATSSTNVHSVTGPGMFERSQRSMDREMAGGDF 2471
BLAST of EMLSAG00000000293 vs. C. finmarchicus
Match: gi|592938103|gb|GAXK01020450.1| (TSA: Calanus finmarchicus comp12086_c0_seq1 transcribed RNA sequence) HSP 1 Score: 33.113 bits (74), Expect = 5.996e+0 Identity = 23/92 (25.00%), Postives = 43/92 (46.74%), Query Frame = 0
Query: 780 EKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVA---WSKKFDVPIEKVYNKT-----QRDKFRWAIEMAGADY 863
E+ +++++ L + E+ +LETQ + N A G+S ++PRI + W + V++ T +R + EMAG D+
Sbjct: 2615 ERSELERREAILAKNREREGRLETQRKNSRGNIEFAFGSSAPRLIEPRIDSSSGYWGSRRATSSTNVHSVTGPGMFERSQRSMDREMAGGDF 2890
BLAST of EMLSAG00000000293 vs. C. finmarchicus
Match: gi|592912910|gb|GAXK01045465.1| (TSA: Calanus finmarchicus comp416754_c0_seq1 transcribed RNA sequence) HSP 1 Score: 31.9574 bits (71), Expect = 7.930e+0 Identity = 15/45 (33.33%), Postives = 25/45 (55.56%), Query Frame = 0
Query: 773 KNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALG 817
K G +E ++MDK KKA+E+T + +KL + + + LG
Sbjct: 617 KTAGERNEALMMDKAKKAMEKTTDPGEKLRCYCLSRGATGILGLG 751
BLAST of EMLSAG00000000293 vs. L. salmonis peptides
Match: EMLSAP00000000293 (pep:novel supercontig:LSalAtl2s:LSalAtl2s1044:15439:19815:-1 gene:EMLSAG00000000293 transcript:EMLSAT00000000293 description:"maker-LSalAtl2s1044-snap-gene-0.46") HSP 1 Score: 1739.93 bits (4505), Expect = 0.000e+0 Identity = 865/865 (100.00%), Postives = 865/865 (100.00%), Query Frame = 0
Query: 1 MGENGTMLHHGSSGLNGEAFTNGSTETKASDHRHSSSKHKHKDKERRKETEEERRVRKEQERKEREDRHKREGRREETEEERRARKEKERREREERHKREGRRDETEEERKVRKEKERKEREERHKREGRRDETEDERRLRKERERKEREERHKREGRREETEEERKARKEKEQRHKSKETEEERRVRKDKERAEKEARKRKEMGYDHSMGEEVSFHNHDEEMKMEQQEQQVKDEPQYEEELHEEQDEFEEDRYNNAKQENMEVEVKVQDDSEDDIPLAKKSKNKKRKSRDEDSEDDVPLSKRKKPKVKKVERVEVSKKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGRYLVGFMDRKYSKSNQIRHVKSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
MGENGTMLHHGSSGLNGEAFTNGSTETKASDHRHSSSKHKHKDKERRKETEEERRVRKEQERKEREDRHKREGRREETEEERRARKEKERREREERHKREGRRDETEEERKVRKEKERKEREERHKREGRRDETEDERRLRKERERKEREERHKREGRREETEEERKARKEKEQRHKSKETEEERRVRKDKERAEKEARKRKEMGYDHSMGEEVSFHNHDEEMKMEQQEQQVKDEPQYEEELHEEQDEFEEDRYNNAKQENMEVEVKVQDDSEDDIPLAKKSKNKKRKSRDEDSEDDVPLSKRKKPKVKKVERVEVSKKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGRYLVGFMDRKYSKSNQIRHVKSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF
Sbjct: 1 MGENGTMLHHGSSGLNGEAFTNGSTETKASDHRHSSSKHKHKDKERRKETEEERRVRKEQERKEREDRHKREGRREETEEERRARKEKERREREERHKREGRRDETEEERKVRKEKERKEREERHKREGRRDETEDERRLRKERERKEREERHKREGRREETEEERKARKEKEQRHKSKETEEERRVRKDKERAEKEARKRKEMGYDHSMGEEVSFHNHDEEMKMEQQEQQVKDEPQYEEELHEEQDEFEEDRYNNAKQENMEVEVKVQDDSEDDIPLAKKSKNKKRKSRDEDSEDDVPLSKRKKPKVKKVERVEVSKKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGRYLVGFMDRKYSKSNQIRHVKSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|12644118|sp|P11387.2|TOP1_HUMAN (RecName: Full=DNA topoisomerase 1; AltName: Full=DNA topoisomerase I) HSP 1 Score: 639.032 bits (1647), Expect = 0.000e+0 Identity = 330/553 (59.67%), Postives = 401/553 (72.51%), Query Frame = 0
Query: 362 DGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
+G KWKFL+H+GP+FAP Y+ LP+ V FYY+ K MKLS + EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT EE++IITNLSKCDF +++ Y+K +E RK SKEEK KE+N + E+G C++DNH E+I NF+IEPPGLFRGR +G + R+ K ++RH +K + +IK K + YE AR LK ++KIR+ Y D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI LH DG++Y VEFDFLGKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT ILN++L LM+GLTAKVFRT+NAS TLQ QL+ELT D+N+PAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK+E A +DLK AK K K V++ KKKA++R EQL KLE QA D+EENK IALGTSKLNYLDPRI+VAW KK+ VPIEK+YNKTQR+KF WAI+MA DY F
Sbjct: 213 EGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTKIDAKKEQLADARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF 765
BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|38503303|sp|Q7YR26.1|TOP1_CHLAE (RecName: Full=DNA topoisomerase 1; AltName: Full=DNA topoisomerase I) HSP 1 Score: 638.262 bits (1645), Expect = 0.000e+0 Identity = 330/552 (59.78%), Postives = 399/552 (72.28%), Query Frame = 0
Query: 363 GTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
G KWKFL+H+GP+FAP Y+ LP V FYY+ K MKLS + EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT EE++IITNLSKCDF +++ Y+K +E RK SKEEK KE+N + E+G C++DNH E+I NF+IEPPGLFRGR +G + R+ K ++RH +K + +IK K + YE AR LK ++KIR+ Y D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI LH DG++Y VEFDFLGKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT ILN++L LM+GLTAKVFRT+NAS TLQ QL+ELT D+N+PAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK+E A +DLK AK K K V++ KKKA++R EQL KLE QA D+EENK IALGTSKLNYLDPRI+VAW KK+ VPIEK+YNKTQR+KF WAI+MA DY F
Sbjct: 216 GIKWKFLEHKGPVFAPPYEPLPDSVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKEQLADARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF 767
BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|51316560|sp|Q9WUL0.1|TOP1_RAT (RecName: Full=DNA topoisomerase 1; AltName: Full=DNA topoisomerase I) HSP 1 Score: 634.795 bits (1636), Expect = 0.000e+0 Identity = 330/552 (59.78%), Postives = 398/552 (72.10%), Query Frame = 0
Query: 363 GTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
G KWKFL+H+GP+FAP Y+ LP+GV FYY+ K MKLS + EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT +E++ ITNLSKCDF +++ Y+K SE RK SKEEK KE+N + E+G CV+DNH E+I NF+IEPPGLFRGR +G + R+ K ++RH +K + +IK K + YE AR LK ++KIR+ Y D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI LH DG++Y VEFDF GKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT ILN++L LM+GLTAKVFRT+NAS TLQ QL+ELT D+NVPAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK++ A KDLK AK K K V++ KKKA++R EQL KLE QA D+EENK IALGTSKLNYLDPRI+VAW KK+ VPIEK+YNKTQR+KF WAI+M DY F
Sbjct: 216 GIKWKFLEHKGPVFAPPYEPLPEGVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNDEKNTITNLSKCDFTQMSQYFKAQSEARKQMSKEEKLKIKEENEKLLKEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARKDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 767
BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|586107|sp|Q07050.1|TOP1_CRIGR (RecName: Full=DNA topoisomerase 1; AltName: Full=DNA topoisomerase I) HSP 1 Score: 632.484 bits (1630), Expect = 0.000e+0 Identity = 328/552 (59.42%), Postives = 398/552 (72.10%), Query Frame = 0
Query: 363 GTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
G KWKFL+H+GP+FAP Y+ LP+GV FYY+ K MKLS + EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT +E+++ITNLSKCDF +++ Y+K SE RK SKEEK KE+N + E+G CV+DNH E+I NF+IEPPGLFRGR +G + R+ K ++RH +K + +IK K + YE AR LK ++KIR+ Y D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTV CCSLRVEHI LH DG++Y VEFDF GKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT ILN++L LM+GLTAKVFRT+NAS TLQ QL+ELT D+NVPAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK++ A +DLK AK K K V++ KKKA++R EQL KLE QA D+EENK IALGTSKLNYLDPRI+VAW KK+ VPIEK+YNKTQR+KF WAI+M DY F
Sbjct: 216 GIKWKFLEHKGPVFAPPYEPLPEGVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNDEKNVITNLSKCDFTQMSQYFKDQSEARKQMSKEEKLKIKEENEKLLKEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVSCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 767
BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|158518540|sp|Q04750.2|TOP1_MOUSE (RecName: Full=DNA topoisomerase 1; AltName: Full=DNA topoisomerase I) HSP 1 Score: 631.713 bits (1628), Expect = 0.000e+0 Identity = 328/552 (59.42%), Postives = 397/552 (71.92%), Query Frame = 0
Query: 363 GTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
G KWKFL+H+GP+FAP Y+ LP+ V FYY+ K MKLS + EEVA F+A+ ++HEYT KE+F +NFFKDWRK MT +E++ ITNLSKCDF +++ Y+K SE RK SKEEK KE+N + E+G CV+DNH E+I NF+IEPPGLFRGR +G + R+ K ++RH +K + +IK K + YE AR LK ++KIR+ Y D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI LH DG++Y VEFDF GKDSIRY+N VPVEKRVFKN+QLFMENK+ EDDLFDRLNT ILN++L LM+GLTAKVFRT+NAS TLQ QL+ELT D+NVPAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK++ A +DLK AK K K V++ KKKA++R EQL KLE QA D+EENK IALGTSKLNYLDPRI+VAW KK+ VPIEK+YNKTQR+KF WAI+M DY F
Sbjct: 216 GIKWKFLEHKGPVFAPPYEPLPESVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNDEKNTITNLSKCDFTQMSQYFKAQSEARKQMSKEEKLKIKEENEKLLKEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 767
BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|1174739|sp|P41512.1|TOP1_XENLA (RecName: Full=DNA topoisomerase 1; AltName: Full=DNA topoisomerase I) HSP 1 Score: 609.372 bits (1570), Expect = 0.000e+0 Identity = 312/537 (58.10%), Postives = 385/537 (71.69%), Query Frame = 0
Query: 362 DGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRG------------RYLVGFMDRKYSKSNQI------------RH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQR 849
DG KWKFL+H+GP+FAP Y+ +P V FYY+ +KLS + EEVA F+A+ ++HEYT K++F +NFFKDW+K MT +ER++ITNLSKCDF ++ Y+K+ SE RKN +KEEK K +N + E+G C++DNH E+I NFRIEPPGLFRG R + + SK ++I RH +K + +IK K + YE AR LK +EKIR+ Y D+KSKEM+VRQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHI L DG+++ VEFDF GKDSIRY+N VPVEKRVFKN+QLFMENK+ +DDLFDRLNT+ILN++L LM+GLTAKVFRT+NAS TLQ QL+ELT +DDNVPAK+LSYNRANR VAILCNHQRA PKT +KSM NLQ KI AK++ A ++ K AK K K +++ KKKA++R EQL KLE QA D+EENK IALGTSKLNYLDPRISVAW KK+ VPIEK+YNKTQR
Sbjct: 269 DGIKWKFLEHKGPVFAPPYEPVPDNVKFYYDGNLVKLSPKAEEVATFFAKMLDHEYTTKDIFRKNFFKDWKKEMTTDERNLITNLSKCDFNAMSLYFKEQSEARKNMTKEEKLKIKAENERLLQEYGYCIMDNHKERIANFRIEPPGLFRGRGDHPKMGKLKKRIMPEDIIINCSKDSKIPVAPAGHKWKEVRHDGKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKMCVEKIRNTYKEDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLFQELDGQEFVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMENKQPDDDLFDRLNTSILNKHLQDLMEGLTAKVFRTYNASITLQQQLDELTNSDDNVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQGKIDAKKDQLADARREFKSAKADAKVRRDEKTKKLVESKKKAVQRIEEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKYGVPIEKIYNKTQR 805
BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|20140694|sp|Q969P6.1|TOP1M_HUMAN (RecName: Full=DNA topoisomerase I, mitochondrial; Short=TOP1mt; Flags: Precursor) HSP 1 Score: 598.201 bits (1541), Expect = 0.000e+0 Identity = 303/560 (54.11%), Postives = 385/560 (68.75%), Query Frame = 0
Query: 355 WEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKY-----------------------------------------SKSNQIRHVK----SFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEK-DEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
WE+EK +DG KW+ L+H+GP FAP Y+ LP GV F+Y + ++LS EEVA FY R ++HEYT KEVF +NFF DWRK M EER++I +L KCDF EI+ Y+ + RK S+EEK+ KE+ +Q EFG C++D H EKIGNF+IEPPGLFRGR +G + R+ S N I+++ S LK + +E AR L+ +++IR Y D+KS+EM+ RQR+VALYFIDKLALRAGNEK D + ADTVGCCSLRVEH+ LH DG + VEFDFLGKD IRY+N VPVEK V+KN+QLFMENK DDLFDRL TT LN++L LM GLTAKVFRT+NAS TLQ+QL LT A+D++ AK+LSYNRANR VAILCNHQRA P T +KSMQNLQ KI+AK+E +A +L++A+ +K G + V++KK++ LE+ EQL +L QA DKEENK +ALGTSKLNYLDPRIS+AW K+F VP+EK+Y+KTQR++F WA+ MAG D+ F
Sbjct: 42 WEKEKHEDGVKWRQLEHKGPYFAPPYEPLPDGVRFFYEGRPVRLSVAAEEVATFYGRMLDHEYTTKEVFRKNFFNDWRKEMAVEEREVIKSLDKCDFTEIHRYFVDKAAARKVLSREEKQKLKEEAEKLQQEFGYCILDGHQEKIGNFKIEPPGLFRGRGDHPKMGMLKRRITPEDVVINCSRDSKIPEPPAGHQWKEVRSDNTVTWLAAWTESVQNSIKYIMLNPCSKLKGETAWQKFETARRLRGFVDEIRSQYRADWKSREMKTRQRAVALYFIDKLALRAGNEKEDGEAADTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCIRYYNRVPVEKPVYKNLQLFMENKDPRDDLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEARAELRRARAEHKAQGDGKSRSVLEKKRRLLEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKIYSKTQRERFAWALAMAGEDFEF 601
BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|267147|sp|P30189.1|TOP1_DROME (RecName: Full=DNA topoisomerase 1; AltName: Full=DNA topoisomerase I) HSP 1 Score: 595.504 bits (1534), Expect = 0.000e+0 Identity = 311/552 (56.34%), Postives = 383/552 (69.38%), Query Frame = 0
Query: 362 DGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYSKSN---------------------QIRH------VKSFLKIKRG-------------KG-----YYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
DG KW L+H+GP+FAP Y+R+P+ V FYY+ K ++LS ETEE A FYA+ + H+Y KEVFN NFFKD+RK MT ER+II + KC+F+E+ Y++ SE+RK SKEEK +K +N A+ EFG C+ID H EKIGNFR+EPPGLFRGR +G + R+ S+ ++RH + S+++ +G KG YE AR L I+KIR Y ++KSKEMRVRQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEH+ LH +GK+ V FDF GKDSIRY+N V VEKRVFKN++LFME+K+ DDLFDRLNT +LNE+L LM+GLTAKVFRT+NAS TLQ QL+ LT+ VP K+L+YNRANR VAILCNHQR+ PK+H+KSM+NL++KIKAKREA EK E + +KK K LER +QL KLE Q D++ENKTIALGTSKLNYLDPRISVAW KK DVPIEK++NKTQR KF WA+ MA +Y F
Sbjct: 436 DGVKWSTLEHKGPVFAPRYERVPRNVRFYYDGKPLELSEETEEAATFYAKMLNHDYCTKEVFNNNFFKDFRKSMTPREREIIKDFRKCNFQEMFNYFQAESEKRKAASKEEKLIKKNENEALMKEFGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIQASDVSINCGKDSKVPSPPPGSRWKEVRHDNTVTWLASWIENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLELFMEHKKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEKIKAKREAIEKCESEYHSRD---------------EKKGKQLERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQRTKFLWAVHMADENYRF 972
BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|259533973|sp|A9Q1D5.1|TOP1M_PANTR (RecName: Full=DNA topoisomerase I, mitochondrial; Short=TOP1mt; Flags: Precursor) HSP 1 Score: 593.578 bits (1529), Expect = 0.000e+0 Identity = 302/560 (53.93%), Postives = 384/560 (68.57%), Query Frame = 0
Query: 355 WEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKY-----------------------------------------SKSNQIRHVK----SFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEK-DEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
WE+EK +DG KW+ L+H+GP FAP Y+ LP GV F+Y K ++LS EEVA FY R + HEYT KEVF +NFF DWRK M EER++I +L KCDF EI+ Y+ + RK S+EEK+ KE+ +Q EFG C++D H EKIGNF+IEPPGLFRGR +G + R+ S N I+++ S LK + +E AR L+ +++IR Y D+KS+EM+ RQR+VALYFIDKLALRAGNEK D + ADTVGCCSLRVEH+ LH DG + VEFDFLGKD IRY+N VPVEK V+KN+QLFME+K D+LFDRL TT LN++L LM GLTAKVFRT+NAS TLQ+QL LT A+D++ AK+LSYNRANR VAILCNHQRA P T +KSMQNLQ KI+AK+E +A +L++A+ +K G + V++KK++ LE+ EQL +L QA DKEENK +ALGTSKLNYLDPRIS+AW K+F VP+EK+Y+KTQR++F WA+ MAG D+ F
Sbjct: 42 WEKEKHEDGVKWRQLEHKGPYFAPPYEPLPDGVRFFYEGKPVRLSVAAEEVATFYGRMLGHEYTTKEVFRKNFFNDWRKEMAVEEREVIKSLDKCDFTEIHRYFVDKAAARKVLSREEKQKLKEEAEKLQREFGYCILDGHQEKIGNFKIEPPGLFRGRGDHPKMGMLKRRIMPEDVVINCSRDSKIPEPPAGHQWKEVRSDNTVTWLAAWTESVQNSIKYIMLNPCSKLKGETAWQKFETARRLRGFVDEIRSQYRADWKSREMKTRQRAVALYFIDKLALRAGNEKEDGEAADTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCIRYYNRVPVEKPVYKNLQLFMESKGPRDNLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLRALTRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEARAELRRARAEHKAQGDGKSRSVLEKKRRLLEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCKRFRVPVEKIYSKTQRERFAWALAMAGEDFEF 601
BLAST of EMLSAG00000000293 vs. SwissProt
Match: gi|74957937|sp|O17966.1|TOP1_CAEEL (RecName: Full=DNA topoisomerase 1; AltName: Full=DNA topoisomerase I; Short=topoI) HSP 1 Score: 547.74 bits (1410), Expect = 0.000e+0 Identity = 313/575 (54.43%), Postives = 381/575 (66.26%), Query Frame = 0
Query: 350 EVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGRYL---VGFMDRKYS---------------------KSNQIRH----------VKSFL------------KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQA-DTVGCCSLRVEHITLHTV-------KDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGA---DYVF 865
++W+WW+EEK G KW LQH GPLFAP Y LP VHF Y +KMKL+ ETEE+A FYA ++HEY+ KE FN+NF KDWRKVMT EER+ I +L KCDFR I+ Y K+ E RK +KEEK KE+ A +GI +ID H +K+ NFRIEPPG+FRGR +G + ++ K ++RH +S L KIK K + YE AR LK KI IR+ YT DFKSKEMRVRQR+ ALYFIDKLALRAGNEKD D+A DTVGCCSLRVEHI L K K++ VEFDFLGKDSIRY N V VEKRV+KN+++FME K DDLFDRL+T LN++L SLM GLT KVFRT+NAS TLQ+QL +LT DNV AK+LSYNRANR+VAILCNHQRA K D+SMQ L+ KIK K++ ++AE LK A+ A K +K +K +R EQL KL+ DK+ENK IALGTSKLNY+DPRI+VAW KKF+VP+EKV+ KT R+KFRWAI+M + +YVF
Sbjct: 243 DIWEWWKEEKKPAGVKWNSLQHCGPLFAPPYIPLPSHVHFKYGGEKMKLTLETEEIAQFYAGVLDHEYSTKEAFNKNFMKDWRKVMTVEERERIHDLKKCDFRAIDAYQKEQREIRKAMTKEEKLKIKEEKEAEVKIYGIAIIDGHRQKVANFRIEPPGVFRGRGGHPKMGLIKKRIMPEDVIINCGKDTEIPKPPPGHKWKEVRHDNTVTWLCSWTESVLGQNKYIMLNPSSKIKGEKDFEKYETARRLKKKIGGIRERYTDDFKSKEMRVRQRATALYFIDKLALRAGNEKDVDEAADTVGCCSLRVEHIKLFDSAKLNEDDKKEKEFVVEFDFLGKDSIRYFNRVSVEKRVYKNLKIFMEGKAPSDDLFDRLDTATLNDHLRSLMDGLTVKVFRTYNASITLQEQLIKLTNPKDNVAAKILSYNRANRQVAILCNHQRAVSKGFDESMQKLEQKIKDKKKEVKEAEAALKSARGAEK-----------EKAQKKYDRLKEQLKKLKISRTDKDENKQIALGTSKLNYIDPRITVAWCKKFEVPLEKVFTKTHREKFRWAIDMTNSSDEEYVF 806
BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: gb|EFA03005.1| (DNA topoisomerase 1-like Protein [Tribolium castaneum]) HSP 1 Score: 715.301 bits (1845), Expect = 0.000e+0 Identity = 382/672 (56.85%), Postives = 481/672 (71.58%), Query Frame = 0
Query: 260 ENMEVEVKVQDDSEDDIPLAKKSKNKKRKSRDE-DSEDDVPLSKRKKPKVKKVERVEVSKKSKSSKKNH-----------------KVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKY-----------------------------------------SKSNQIRHV----KSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
E+ +VK ++DS++D+PL+ + ++ K + E D EDD+PL+ RKKPK +K E+ E KK +S + + +K E SP K G +KK+E+ EVWKWWEEEK DDG KWKFL+H+GP+FAP Y+ LP V FYY+ K+MKL+ E EEVA FY++ ++H+YT KEVFN NFFKDWRKVM+ ER +I +L KC+F+ ++ YY ++E+ +NR+KEEK+A KEKN A+ E+G C ID H EKIGNF+IEPPGLFRGR +G + R+ + NQ++++ S LK ++ YE AR L I+KIR++Y D+KSKEMR+RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHI+LH KDGK+Y V FDFLGKDSIRY+N VPVEKRVFKN+QLFME+K DDLFDRLNT I+N++LN LM+GLTAKVFRT+NAS+TLQ QL++LT ADD+V K+L+YNRANR VAILCNHQR+ PK H+KSM+ L++KI AK+EA + AE+ +K A K K+ GS EK V DKKKK L+R EQL KLE Q D++ENKTIALGTSKLNYLDPRISVAW KK+ VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct: 273 EDSTADVKQEEDSDEDLPLSARMEHTSVKRKIESDDEDDMPLNARKKPKKEKKEKSEKKKKKRSVEDDEEEWDRPVKKEKIKKEKDSIKTENESPKKGGRKKKEEEPQEVWKWWEEEKKDDGKKWKFLEHKGPVFAPPYEPLPDHVKFYYDGKEMKLTPEAEEVASFYSKMLDHDYTTKEVFNNNFFKDWRKVMSESERKVIKDLKKCNFKSMHAYYMDLAEKNRNRTKEEKQALKEKNEALIKEYGFCNIDGHKEKIGNFKIEPPGLFRGRGEHPKMGMLKRRVEAEDIIINCSQDSKIPEPPPGHKWKEVRHDDNVTWLASWTENVQNQVKYIMLNPSSKLKGEKDWQKYETARRLHKCIDKIREEYKDDWKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHISLHKEKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMEHKSPGDDLFDRLNTAIMNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTNADDSVAEKILAYNRANRAVAILCNHQRSVPKGHEKSMEKLKEKIDAKKEAIKDAERQVKDAAKDAKH-GSVKEKTVYDKKKKMLQRLKEQLTKLEIQETDRDENKTIALGTSKLNYLDPRISVAWCKKYGVPIEKIYNKTQRDKFRWAIDMAGPDYVF 943
BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: XP_396203.4 (PREDICTED: DNA topoisomerase I, mitochondrial isoform X1 [Apis mellifera]) HSP 1 Score: 711.064 bits (1834), Expect = 0.000e+0 Identity = 383/661 (57.94%), Postives = 470/661 (71.10%), Query Frame = 0
Query: 266 VKVQDDSEDDIPLAKKS--KNKKRKSRDEDSEDDVPLSKRKKPKVKKVERVEVSKKSKSSKKNHKVKHEVVSPTKSGGR-----------KKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR-----------------YLVGFM-DRKYSKSN------QIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
+K +++S++D+PL+ +S ++S D + E+DVPLS RKK K + + +K + + +++ + P K G R KK+E++ EVWKWWEEEK +DGTKW FL+H+GP+FAP Y+ LP V+FYYN K+MKLS +TEEVA FYAR ++H+YT K FN NFF DWR+VMT ER I +LSKC+F+EI+ Y+ + SEERK +KEEK+ KEKN IQ E+G C+ID H EKIGNF+IEPPGLFRGR L+ D K +IRH VK + K+K K + YE AR+L I+KIR +Y D+KSKEMR+RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLH KDGK+Y V FDFLGKDSIRY+N VPVEKRVFKN+QLFMENK DDLFDRLNTT++N++LN LM+GLTAKVFRT+NAS+TLQ QL++LT DD K+LSYNRANR VAILCNHQR+ PKTH KSM+NL+ KI+AK++A AE +K AK+ K+ GS EKV +KKKKAL+R EQL KLE QA DKEENK IALGTSKLNYLDPRI+VAW KK +VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct: 370 IKTEEESDEDVPLSARSMAPTSIKRSLDSEEEEDVPLSARKKSKKSDTKTKKKKRKYEDDEDEDEIEQK---PKKKGARTSKGENSSPRKKKQEEEQEVWKWWEEEKKNDGTKWTFLEHKGPVFAPPYEPLPPDVNFYYNGKEMKLSQDTEEVATFYARMLDHDYTTKPAFNSNFFHDWREVMTESERTKIVDLSKCNFKEIHAYFIQKSEERKAMTKEEKQKIKEKNEEIQKEYGYCIIDGHKEKIGNFKIEPPGLFRGRGEHPKMGKLKKRVMPEDILINCSKDSNIPKPPPGHKWKEIRHDPNVTWLASWTENIQGQVKYVMLNPSSKLKGEKDWQKYEIARKLAQLIDKIRAEYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKSPSDDLFDRLNTTVMNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTNPDDTEAEKILSYNRANRAVAILCNHQRSVPKTHAKSMENLKAKIEAKKQAINDAELAVKDAKRDAKH-GSVKEKVTYEKKKKALDRLKEQLTKLEVQATDKEENKEIALGTSKLNYLDPRITVAWCKKHNVPIEKIYNKTQRDKFRWAIDMAGPDYVF 1026
BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: EEB15907.1 (DNA topoisomerase, putative [Pediculus humanus corporis]) HSP 1 Score: 694.886 bits (1792), Expect = 0.000e+0 Identity = 376/646 (58.20%), Postives = 461/646 (71.36%), Query Frame = 0
Query: 269 QDDSEDDIPLAKKSKNKKRKSR-DEDSEDDVPLSKRKKPKVKKVERVEVSKKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFM---------------DRKYSKS------NQIRH------VKSFLKIKRGKGYY------------------EKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
Q+DS+DD KK+K KKRKS+ D DSEDD KP KK + + K+ K K SP K KK+E++ +VWKWWEEEK +DG KWKFL+H+GPLFAP Y+RLPK V F+Y+ K++ LS E EEVA FYA+ + H+YT KE FN NFF DWRKVMT +ER +IT+LSKC+F+ + Y+++ SEERK SKEEKK K++N AIQ E+G C ID H EKIGNFRIEPPGLFRGR +G + D K K +++H + S+ + +G Y E AR+L KI+KIR+ Y D+KSKEM++RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEH+ L+ +GK+ V FDFLGKDSIRY+N VPVEKRVFKN+ LF ENK+ +DDLFDRLNTT+LN++LN LM+GLTAKVFRT+NAS+TLQ+QL+ELT DD V K+L+YNRANR VAILCNHQR+ PK+H+KSM+NL+ KI+AKRE + +K++K AK +NG S +E KKKK L+R EQL KLE Q DKEENKTIALGTSKLNYLDPRISVAW KK++VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct: 340 QEDSDDDFKPGKKTKGKKRKSKGDSDSEDDF------KPAAKKPSKTVIKKEVK--------KETTTSPKKV---KKEEEQQDVWKWWEEEKREDGKKWKFLEHKGPLFAPLYERLPKSVKFFYDGKEISLSEEAEEVATFYAKMLTHDYTTKEKFNTNFFNDWRKVMTDKERKVITDLSKCNFKPMALYFQEKSEERKAMSKEEKKVIKDQNDAIQKEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGMLKKRVLPEDVIINCSKDSKIPKPPDGHKWKKVQHDPSVTWLASWTENVQGNVKYVMLNPSSKLKGEKDMVKYETARKLAKKIDKIREQYQADWKSKEMKIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVELYPELNGKENVVVFDFLGKDSIRYYNEVPVEKRVFKNLLLFKENKQPQDDLFDRLNTTVLNKHLNELMEGLTAKVFRTYNASWTLQEQLKELTNPDDTVAEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKAKIEAKREQINEIKKEVKNAK---RNGDSGTEA----KKKKQLDRLKEQLLKLEVQETDKEENKTIALGTSKLNYLDPRISVAWCKKYNVPIEKIYNKTQRDKFRWAIDMAGPDYVF 961
BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: XP_016770482.1 (PREDICTED: DNA topoisomerase 1 isoform X2 [Apis mellifera]) HSP 1 Score: 666.381 bits (1718), Expect = 0.000e+0 Identity = 350/559 (62.61%), Postives = 416/559 (74.42%), Query Frame = 0
Query: 355 WEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLF--RGRYL-VGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
WEEEK +DGTKW FL+H+GP+FAP Y+ LP V+FYYN K+MKLS +TEEVA FYAR ++H+YT K FN NFF DWR+VMT ER I +LSKC+F+EI+ Y+ + SEERK +KEEK+ KEKN IQ E+G C+ID H EKIGNF+IEPPGLF RG + +G + ++ K +IRH VK + K+K K + YE AR+L I+KIR +Y D+KSKEMR+RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLH KDGK+Y V FDFLGKDSIRY+N VPVEKRVFKN+QLFMENK DDLFDRLNTT++N++LN LM+GLTAKVFRT+NAS+TLQ QL++LT DD K+LSYNRANR VAILCNHQR+ PKTH KSM+NL+ KI+AK++A AE +K AK+ K+ GS EKV +KKKKAL+R EQL KLE QA DKEENK IALGTSKLNYLDPRI+VAW KK +VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct: 17 WEEEKKNDGTKWTFLEHKGPVFAPPYEPLPPDVNFYYNGKEMKLSQDTEEVATFYARMLDHDYTTKPAFNSNFFHDWREVMTESERTKIVDLSKCNFKEIHAYFIQKSEERKAMTKEEKQKIKEKNEEIQKEYGYCIIDGHKEKIGNFKIEPPGLFRGRGEHPKMGKLKKRVMPEDILINCSKDSNIPKPPPGHKWKEIRHDPNVTWLASWTENIQGQVKYVMLNPSSKLKGEKDWQKYEIARKLAQLIDKIRAEYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKSPSDDLFDRLNTTVMNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTNPDDTEAEKILSYNRANRAVAILCNHQRSVPKTHAKSMENLKAKIEAKKQAINDAELAVKDAKRDAKH-GSVKEKVTYEKKKKALDRLKEQLTKLEVQATDKEENKEIALGTSKLNYLDPRITVAWCKKHNVPIEKIYNKTQRDKFRWAIDMAGPDYVF 574
BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: EGK96321.1 (AGAP004078-PB [Anopheles gambiae str. PEST]) HSP 1 Score: 652.899 bits (1683), Expect = 0.000e+0 Identity = 332/559 (59.39%), Postives = 402/559 (71.91%), Query Frame = 0
Query: 355 WEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYSKSN---------------------QIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
WEEEK DDG KWK+L+H+GP+FAP YD LP V F Y+ K+MKLS + EEVAGFYAR +EH+YT K+ FN NFFKDWRK MT ER+ IT+L KC+FR + Y+ +++E+ +NRSKEEK A K N + E+GICVID H EKIGNF+IEPPGLFRGR +G + R+ + ++RH VK + K+K K + YE AR L I+KIRD Y ++KSKEMR+RQR+VA+YFIDKLALRAGNEKD+DQADTVGCCSLR EHI LH +GK+ V FDFLGKDSIRY+N V VEKRVFKN++LF ENK+ DDLFDRLNT+++NEYL LM GLTAKVFRTFNAS+TLQ QLEELT+ + +VP K+L+YNRANR VAILCNHQRA PKTH+KSM NL++KI+ KRE E+ +K+ K KK+ + + DKK K LER EQL KLE Q D++ENKTIALGTSKLNYLDPRISVAW KKF VPIEK++NKTQRDKFRWAI+MA +YVF
Sbjct: 28 WEEEKRDDGVKWKYLEHKGPVFAPPYDPLPSHVKFMYDGKEMKLSQDAEEVAGFYARMLEHDYTSKQAFNDNFFKDWRKTMTPHERERITDLEKCNFRPMAAYFAEIAEQNRNRSKEEKAALKAANEQLTKEYGICVIDGHKEKIGNFKIEPPGLFRGRGEHPKMGLVKRRVMPEDVIINCSQDSKIPSPPPGRRWKEVRHDNTVSWLASWVENVQGQVKYIMLNPSSKLKGEKDWQKYETARRLLKHIDKIRDTYRDEWKSKEMRIRQRAVAMYFIDKLALRAGNEKDDDQADTVGCCSLRYEHIALHKELNGKENVVVFDFLGKDSIRYYNEVEVEKRVFKNLELFKENKKPGDDLFDRLNTSVVNEYLKGLMDGLTAKVFRTFNASYTLQKQLEELTDPNMSVPEKLLAYNRANRAVAILCNHQRAVPKTHEKSMGNLKEKIRVKREQVEQCQKEFKDLKKS-----NVRDPSAFDKKSKQLERLKEQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKFGVPIEKIFNKTQRDKFRWAIDMADENYVF 581
BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: EAA05377.5 (AGAP004078-PA [Anopheles gambiae str. PEST]) HSP 1 Score: 651.744 bits (1680), Expect = 0.000e+0 Identity = 327/553 (59.13%), Postives = 397/553 (71.79%), Query Frame = 0
Query: 361 DDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYSKSN---------------------QIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
DDG KWK+L+H+GP+FAP YD LP V F Y+ K+MKLS + EEVAGFYAR +EH+YT K+ FN NFFKDWRK MT ER+ IT+L KC+FR + Y+ +++E+ +NRSKEEK A K N + E+GICVID H EKIGNF+IEPPGLFRGR +G + R+ + ++RH VK + K+K K + YE AR L I+KIRD Y ++KSKEMR+RQR+VA+YFIDKLALRAGNEKD+DQADTVGCCSLR EHI LH +GK+ V FDFLGKDSIRY+N V VEKRVFKN++LF ENK+ DDLFDRLNT+++NEYL LM GLTAKVFRTFNAS+TLQ QLEELT+ + +VP K+L+YNRANR VAILCNHQRA PKTH+KSM NL++KI+ KRE E+ +K+ K KK+ + + DKK K LER EQL KLE Q D++ENKTIALGTSKLNYLDPRISVAW KKF VPIEK++NKTQRDKFRWAI+MA +YVF
Sbjct: 541 DDGVKWKYLEHKGPVFAPPYDPLPSHVKFMYDGKEMKLSQDAEEVAGFYARMLEHDYTSKQAFNDNFFKDWRKTMTPHERERITDLEKCNFRPMAAYFAEIAEQNRNRSKEEKAALKAANEQLTKEYGICVIDGHKEKIGNFKIEPPGLFRGRGEHPKMGLVKRRVMPEDVIINCSQDSKIPSPPPGRRWKEVRHDNTVSWLASWVENVQGQVKYIMLNPSSKLKGEKDWQKYETARRLLKHIDKIRDTYRDEWKSKEMRIRQRAVAMYFIDKLALRAGNEKDDDQADTVGCCSLRYEHIALHKELNGKENVVVFDFLGKDSIRYYNEVEVEKRVFKNLELFKENKKPGDDLFDRLNTSVVNEYLKGLMDGLTAKVFRTFNASYTLQKQLEELTDPNMSVPEKLLAYNRANRAVAILCNHQRAVPKTHEKSMGNLKEKIRVKREQVEQCQKEFKDLKKS-----NVRDPSAFDKKSKQLERLKEQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKFGVPIEKIFNKTQRDKFRWAIDMADENYVF 1088
BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: EFX74248.1 (hypothetical protein DAPPUDRAFT_109061 [Daphnia pulex]) HSP 1 Score: 635.565 bits (1638), Expect = 0.000e+0 Identity = 325/522 (62.26%), Postives = 394/522 (75.48%), Query Frame = 0
Query: 355 WEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYSKSNQIRHVKSFLKIKRGKGY-YEKARE------LKSKIEKIRD-DYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
WEEEK +DG KWK L+H+GP+FA Y+ LP V F YN ++MKLS+ EEV FYA ++H+Y K+VFN+NFFKDWRK MT E++IIT+L KCDF + TY+K SEERKNR+KEEK K +N + E+G C+ID H ++IGNF+IEPPGLFRGR +G + R+ + I + K G+ +++ R L S E ++ Y D+KSKEM++RQRSVALYFIDKLALRAGNEKDEDQADTVG CSLRVEHI+LH K+GK V FDFLGKDSIRY+N VPVEKRVFKN+Q+FMENK+ DDLFDRLNTTI+N++LN LM+GLTAKVFRTFNAS TLQ+QL+ELT+ +V K+L+YNRANR VAILCNHQRA PKT KSM+NLQ KI AKREA E AEK K KK K GS + K+ KK+K +E+ EQL KLE QA D+EENK IALGTSKLNYLDPRISVAW KK DVPIEK+YNKTQR+KF+WAI+MAG ++VF
Sbjct: 22 WEEEKHEDGVKWKSLEHKGPVFATQYEPLPGNVKFKYNGQEMKLSTAAEEVGSFYAAMLDHDYVTKDVFNKNFFKDWRKFMTHSEKEIITDLKKCDFTYMLTYFKAKSEERKNRTKEEKLQLKTENEEMVKEYGWCIIDGHKQRIGNFKIEPPGLFRGRGDHPKMGMVKRRVMPEDVIINCTKGTAPKPPPGHKWKEVRSDNTVTWLASWTENVQGQTYKEDWKSKEMKIRQRSVALYFIDKLALRAGNEKDEDQADTVGACSLRVEHISLHEQKEGKQCVVVFDFLGKDSIRYYNEVPVEKRVFKNLQIFMENKKPGDDLFDRLNTTIMNKHLNDLMEGLTAKVFRTFNASNTLQEQLDELTDPKSSVTEKILAYNRANRAVAILCNHQRAVPKTFAKSMENLQVKITAKREAIEDAEKSFKDLKKEAKKTGSAAAKIAAGKKEKQVEKLKEQLMKLEVQATDREENKEIALGTSKLNYLDPRISVAWCKKNDVPIEKIYNKTQREKFQWAIDMAGPEFVF 543
BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: gb|KPM06386.1| (DNA topoisomerase 1-like protein [Sarcoptes scabiei]) HSP 1 Score: 619.772 bits (1597), Expect = 0.000e+0 Identity = 327/564 (57.98%), Postives = 396/564 (70.21%), Query Frame = 0
Query: 351 VWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR-----------------YLVGFMDRKYS-------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQ-ADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
+WKWWEEE+ +G KWK L+H GP+F PDY+ LPK V FYYN K M+LS EEVA FYA+ ++H+YT K+VFN+NFFKDWRK MT +E++IIT+LS C+F+++N Y+K +E+RK +KEEK K+KN ++G C++D H +KIGNFRIEPPGLFRGR ++ D+ + K +IRH VK + K+K K + YEKARELK + KIR DY DFKS EM RQR+VALYFIDKLALRAGNEK+E + ADTVGCCSLRVEHITL+ K+G Y V+FDFLGKDSIRY N V VEKRVFKN++ F+++K+ DDLFDRL T+ LN+YLNSLM GLTAKVFRT+NAS TLQ QL ELT+AD N+P KML+YNRANR VA+LCNHQRA PKT DK M+NL KI+ K+ +K+ KK YK S + DK KK L+ EQL KLE Q VDKEENK IALGTSKLNYLDPRISVAW KK+ VPI+K+YNKTQRDKFRWAIEM G DY F
Sbjct: 218 IWKWWEEERPGEGIKWKTLEHNGPVFPPDYEPLPKNVKFYYNGKHMELSPGAEEVASFYAKMLDHDYTSKDVFNKNFFKDWRKTMTDKEKEIITDLSLCNFKKMNEYFKDQTEKRKQMTKEEKLEIKKKNEEAVLKYGYCIVDGHKQKIGNFRIEPPGLFRGRGEHPKMGKLKKRVQPEDIIINIGDKAKAPIPPAGHKWKEIRHDNTVTWLASWTENIMGNVKYIMLNPSSKLKSIKDWQKYEKARELKKYVAKIRADYRTDFKSHEMMKRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHITLNEEKNGNQYVVDFDFLGKDSIRYINSVSVEKRVFKNLKHFIQHKQPGDDLFDRLTTSSLNKYLNSLMDGLTAKVFRTYNASNTLQQQLNELTKADMNLPEKMLAYNRANRSVALLCNHQRAVPKTFDKQMENLSVKIQDKKSQ-------IKEQKKIYKE--SKGDSAARDKHKKKLKTLEEQLKKLEVQKVDKEENKQIALGTSKLNYLDPRISVAWCKKWQVPIDKIYNKTQRDKFRWAIEMVGPDYQF 772
BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: AHN59737.1 (topoisomerase 1, isoform E [Drosophila melanogaster]) HSP 1 Score: 606.29 bits (1562), Expect = 0.000e+0 Identity = 316/561 (56.33%), Postives = 387/561 (68.98%), Query Frame = 0
Query: 353 KWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYSKS---------------------------NQIRHVKSFLKIKRG-------------KG-----YYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
+WWEEEK DG KW L+H+GP+FAP Y+R+P+ V FYY+ K ++LS ETEE A FYA+ + H+Y KEVFN NFFKD+RK MT ER+II + KC+F+E+ Y++ SE+RK SKEEK +K +N A+ EFG C+ID H EKIGNFR+EPPGLFRGR +G + R+ S N + + S+++ +G KG YE AR L I+KIR Y ++KSKEMRVRQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEH+ LH +GK+ V FDF GKDSIRY+N V VEKRVFKN++LFME+K+ DDLFDRLNT +LNE+L LM+GLTAKVFRT+NAS TLQ QL+ LT+ VP K+L+YNRANR VAILCNHQR+ PK+H+KSM+NL++KIKAKREA EK E + +KK K LER +QL KLE Q D++ENKTIALGTSKLNYLDPRISVAW KK DVPIEK++NKTQR KF WA+ MA +Y F
Sbjct: 48 RWWEEEKRADGVKWSTLEHKGPVFAPRYERVPRNVRFYYDGKPLELSEETEEAATFYAKMLNHDYCTKEVFNNNFFKDFRKSMTPREREIIKDFRKCNFQEMFNYFQAESEKRKAASKEEKLIKKNENEALMKEFGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIQASDVSINCGKDSKVPSPPPGSRWKEVRHDNTVTWLASWIENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLELFMEHKKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEKIKAKREAIEKCESEYHSRD---------------EKKGKQLERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQRTKFLWAVHMADENYRF 593
BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Match: AFH07393.1 (topoisomerase 1, isoform D [Drosophila melanogaster]) HSP 1 Score: 595.504 bits (1534), Expect = 0.000e+0 Identity = 311/552 (56.34%), Postives = 383/552 (69.38%), Query Frame = 0
Query: 362 DGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYSKSN---------------------QIRH------VKSFLKIKRG-------------KG-----YYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
DG KW L+H+GP+FAP Y+R+P+ V FYY+ K ++LS ETEE A FYA+ + H+Y KEVFN NFFKD+RK MT ER+II + KC+F+E+ Y++ SE+RK SKEEK +K +N A+ EFG C+ID H EKIGNFR+EPPGLFRGR +G + R+ S+ ++RH + S+++ +G KG YE AR L I+KIR Y ++KSKEMRVRQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEH+ LH +GK+ V FDF GKDSIRY+N V VEKRVFKN++LFME+K+ DDLFDRLNT +LNE+L LM+GLTAKVFRT+NAS TLQ QL+ LT+ VP K+L+YNRANR VAILCNHQR+ PK+H+KSM+NL++KIKAKREA EK E + +KK K LER +QL KLE Q D++ENKTIALGTSKLNYLDPRISVAW KK DVPIEK++NKTQR KF WA+ MA +Y F
Sbjct: 434 DGVKWSTLEHKGPVFAPRYERVPRNVRFYYDGKPLELSEETEEAATFYAKMLNHDYCTKEVFNNNFFKDFRKSMTPREREIIKDFRKCNFQEMFNYFQAESEKRKAASKEEKLIKKNENEALMKEFGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIQASDVSINCGKDSKVPSPPPGSRWKEVRHDNTVTWLASWIENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLELFMEHKKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEKIKAKREAIEKCESEYHSRD---------------EKKGKQLERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQRTKFLWAVHMADENYRF 970
BLAST of EMLSAG00000000293 vs. nr
Match: gi|343175107|gb|AEM00018.1| (topoisomerase 1B [Spodoptera exigua]) HSP 1 Score: 724.546 bits (1869), Expect = 0.000e+0 Identity = 380/663 (57.32%), Postives = 469/663 (70.74%), Query Frame = 0
Query: 265 EVKVQDDSEDDIPLAKKSKNKKRKSRDEDSEDDVPLSKRKK--------PKVKKVERVEVSKKSKSSKKNHKVKHEVV------SPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFM---------------DRKYSKS------------NQIRHVKSFLKIKRGKGYY------------------EKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
E+ +++S++D P +++ NK+R +SE+D+PL +RKK P E K K K KVK V P+ + +KK+ED+ EVWKWWEEEK DDGTKWKFL+H+GP+FAPDY+ LP+ V FYY+ K+M+LS + EEVAGFYAR ++HEYT K FN NFF DWRKVMT EE II +LSKC+F+E++ Y++ VSE+ +NR+KEEK A K KN IQ E+G C+ID H EKIGNFRIEPPGLFRGR +G + D K K N + + S+ + +G+ Y E AR+L I+ IR++Y D+K+KEMRVRQR+VALYFIDKLALRAGNEKD+DQADTVGCCSLRVEHI LH KDGK+Y V FDFLGKDSIRY+N VPVEKRVFKN++LFMENK+ DDLFDRLNT LNE+L LM GLTAKVFRT+NAS TLQ QL+ELT+A ++P K+L+YNRANR VA+LCNHQRA PK H KSM+ L++KI+AKR+ ++AE+DL++A KA K GS EK+ DKKKKALER EQL KLE Q D++ENKTIALGTSKLNYLDPRISVAW KK VPIEK+YNKTQRDKFRWAI+MAG +Y+F
Sbjct: 271 ELPPEEESDEDSPSSERIGNKRRAP--SESEEDIPLLQRKKSKKKIKKEPTYDDDMDDEEEKPKKKKSKPVKVKQTQVKSEPNDGPSPTKRKKKQEDEPEVWKWWEEEKKDDGTKWKFLEHKGPVFAPDYEPLPENVKFYYDGKEMRLSQDAEEVAGFYARMLDHEYTTKSTFNNNFFNDWRKVMTHEETKIIKDLSKCNFKEMHAYFQSVSEKNRNRTKEEKAALKAKNEEIQKEYGFCIIDGHKEKIGNFRIEPPGLFRGRGEHPKMGMLKRRVMPEDVLINCSKDSKIPKPPPGHKWKEVKHDNTVTWLASWTENVQGQAKYVMLNPSSKLKGEKDWQKYETARKLHKCIDVIRENYKNDWKAKEMRVRQRAVALYFIDKLALRAGNEKDDDQADTVGCCSLRVEHIALHKEKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLELFMENKKDSDDLFDRLNTQTLNEHLKDLMPGLTAKVFRTYNASITLQRQLDELTDASASIPEKILAYNRANRAVAVLCNHQRAVPKGHSKSMEALKEKIQAKRDQVDEAEEDLREAAKAAKR-GSVKEKLACDKKKKALERLREQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHGVPIEKIYNKTQRDKFRWAIDMAGPEYIF 930
BLAST of EMLSAG00000000293 vs. nr
Match: gi|939676204|ref|XP_014284042.1| (PREDICTED: DNA topoisomerase I, mitochondrial [Halyomorpha halys]) HSP 1 Score: 723.391 bits (1866), Expect = 0.000e+0 Identity = 426/843 (50.53%), Postives = 558/843 (66.19%), Query Frame = 0
Query: 86 KEKERREREERHKREGRRDETEEERKVRKEKERKEREERHKREGRRDETEDERRLRKERERKEREERHKREGRREETEEERKARKEKEQRHKSKETEEERRVRKDKERAEKEARKRKEMGYDHSMGEEVSFHNHDEEMKMEQQEQQVKDEPQYEEELHEEQDEFEEDRYNN--AKQENMEVEVKVQDDSEDDIPLAKKSKNKKRKSRDEDSEDDVPLSKRKKPKVKKVERVEVSKKSKSSKKNHKVKH-------------EVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
KEK R + ++RH R+ +RD+ K+K++ + + + KE+ + ++R R+ R+ +++ +++ +++H S + + +KDKER+++ KR E ++ + + S + +E + ++ + +K+EP + L E+Q+ YNN K+E E E Q+DSEDD PL ++ N KR+ + ED E+D+PLS RKK K +K + + + + K E T +KK+E++ EVWKWWEEEK DG KW FL+H+GP+FAP Y+ LP V F+Y+ K+MKLS E EEVA FY R I+HEYT KE FN+NFFKDWRKVMT++E+D+IT+L KC+FR+INTY+ + SEERK SKEEKK KEKN + E+G C+ID H EKIGNF+IEPP LFRGR +G + R+ K ++RH VK + K+K K + YE AR+L I+KIR DY D+KSKEMR+RQR+VA+YFID LALRAGNEKDEDQADTVGCCSLRVEHITLH KDGK+Y V FDFLGKDSIRY+N VP+EKRVFKN+QLFME K+G DDLFDRLNT+ILN++LN LM+GLTAKVFRT+NAS+TLQ QL+ELT+ + VP +L+YNRANR VAILCNHQR+ PKTH SM+ L++KI AK++ E+AEK K AKK KN GS E++V DKKKKAL+R EQL KLE Q D+EENKTIAL TSKLNYLDPRISVAW KK++VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct: 110 KEKHREKDKDRH-RDEKRDKEHRSSSSHKDKDKHSSTNSSSSKDKDKSHSSSKDKDKEKNSSKDKDRSDRDKHRDREKDKDRSKHNGDRKHSSSSSSSREKEKKDKERSKEAKPKRDE--FEEADDFQPSKVSEEEPVVVKSEPVDIKEEPIDDSYLSEDQNSC----YNNLTIKEEEDEAEEPQQEDSEDDAPLLSRTSNIKREIKSEDEEEDIPLSARKKVKKEKTGKRKKESDDEEEDDDFKPVKKKSSTVKKTKVKTEAPEETSPKKKKKQEEEQEVWKWWEEEKRPDGVKWTFLEHKGPVFAPPYEPLPPDVKFFYDGKEMKLSEEAEEVATFYGRMIDHEYTTKEAFNKNFFKDWRKVMTQKEKDVITDLKKCNFRQINTYFLRKSEERKAMSKEEKKVIKEKNEELVKEYGFCIIDGHKEKIGNFKIEPPSLFRGRGEHPKMGMLKRRVQPEDVLINCSKDSKIPKPPEGHKWKEVRHDNTVTWLASWTENVQGQVKYVMLNPSSKLKGEKDWQKYETARKLAHSIDKIRKDYREDWKSKEMRIRQRAVAMYFIDILALRAGNEKDEDQADTVGCCSLRVEHITLHNEKDGKEYVVVFDFLGKDSIRYYNEVPIEKRVFKNLQLFMEGKKGSDDLFDRLNTSILNKHLNELMEGLTAKVFRTYNASWTLQQQLKELTDPNYTVPEMVLAYNRANRAVAILCNHQRSVPKTHQNSMEKLKEKIAAKKDQIEEAEKQYKYAKKDAKN-GSAKERIVADKKKKALDRLREQLTKLEVQETDREENKTIALSTSKLNYLDPRISVAWCKKYNVPIEKIYNKTQRDKFRWAIDMAGPDYVF 944
BLAST of EMLSAG00000000293 vs. nr
Match: gi|939255986|ref|XP_014247767.1| (PREDICTED: DNA topoisomerase I, mitochondrial isoform X1 [Cimex lectularius]) HSP 1 Score: 721.85 bits (1862), Expect = 0.000e+0 Identity = 394/695 (56.69%), Postives = 482/695 (69.35%), Query Frame = 0
Query: 238 YEEELHEEQDEFEEDRYNNAKQENME-VEVKVQDDSEDDIPLAKKSKNKKRKSRDEDSEDDVPLSKRKKPKVKKVERVEVSK----------------KSKSSKKNHKVKHEVVSPTKSGGRKKK--EDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYSKSN-----------------------------------------QIRHV----KSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
Y+E +E+D+ +D YN + ME K ++DSE+DIPL+ + + S D +DDVPL+ RKK K +K + + K K+K+ KK+ KVK E + RKK+ E++ EVWKWWEEEK DG KW FL+H+GP+FAP Y+ LP V FYY+ K+++LS E EEVA FY R IEH+YT+KEVFN NFFKDW+K MT +ER++IT+LSKC+FR IN Y++K SEERK +KEEK K+KN E+G C+ID H EKIGNF+IEPP LFRGR +G + ++ + Q+++V S LK ++ YE AR+L S+I+KIR DY D+KSKEM++RQR+VA+YFIDKLALRAGNEKDEDQADTVGCCSLRVEHI L KDGK+Y V FDFLGKDSIRY+N VPVEKRVFKN+QLF+E K+G DDLFDRLNTT+LN++L LM GLTAKVFRT+NAS+TLQ QL ELT+ D +P L+YNRANR VAILCNHQR+ PK+H KSM+NL++KI KRE E+AEK K AKK KN GS EK+V DKKKKALER EQL KLE Q D+EENKTIALGTSKLNYLDPRISVAW KK +VPIEKVYNKTQRDKFRWAI+MAG DYVF
Sbjct: 288 YDENDFKEEDD--DDSYNLHIETTMEESTFKEEEDSEEDIPLSSR-----KHSMQSDEDDDVPLTSRKKLKTEKQKSSKKRKKSFDSEEEEEDDFKPVKTKAQKKSSKVKQEQNTSATQSPRKKRKLEEEQEVWKWWEEEKKPDGVKWNFLEHKGPVFAPPYEPLPHDVKFYYDGKEVRLSEEAEEVATFYGRMIEHDYTQKEVFNNNFFKDWKKTMTPKERELITDLSKCNFRHINAYFQKKSEERKAMTKEEKAELKKKNEEQVQEYGFCIIDGHKEKIGNFKIEPPSLFRGRGEHPKMGMLKKRVMPEDVSINCSKDSKIPVPPPGHKWKEVKHDNTVTWLASWTENVQGQVKYVMLNPSSKLKGEKDWQKYETARKLASQIDKIRRDYREDWKSKEMKIRQRAVAMYFIDKLALRAGNEKDEDQADTVGCCSLRVEHIQLFPEKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFIEGKKGSDDLFDRLNTTVLNKHLTELMDGLTAKVFRTYNASWTLQQQLNELTKDDYTLPEMCLAYNRANRAVAILCNHQRSVPKSHQKSMENLKEKISNKREQIEEAEKQYKYAKKDAKN-GSAKEKIVADKKKKALERLKEQLRKLEVQETDREENKTIALGTSKLNYLDPRISVAWCKKHNVPIEKVYNKTQRDKFRWAIDMAGPDYVF 974
BLAST of EMLSAG00000000293 vs. nr
Match: gi|307182085|gb|EFN69463.1| (DNA topoisomerase 1 [Camponotus floridanus]) HSP 1 Score: 721.85 bits (1862), Expect = 0.000e+0 Identity = 424/855 (49.59%), Postives = 548/855 (64.09%), Query Frame = 0
Query: 107 EEERKVRKEKERKEREERHKREGRRDE---TEDERRLRKERERKEREERHK-REGRREETEEERKARKEKEQRHKSKETEEERRVRKDKERAEKEARKRKEMGYDHSMGEEVSFHNHDEEMKMEQQEQQVKDEPQYEEELHEEQDEF--------EEDRYNNAKQENMEVE----------------VKVQDDSEDDIPLAKKSKNKKRKSR--DEDSEDDVPLSKRKKPKVKKV---------------ERVEVSKKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR-----------------------------------------------YLVGFMDRKYSKSNQIRHV----KSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
+++R + K+KER+ + +H G RD+ + KE+ R +++ K RE +++ + K+K++ K + + ++DK++ E + ++ +M +H+ E FH ++ E+K E +K+EP + EL E+ D EED A +E ++ +K ++DSE+D PL+ +SK R + D E+DVPLS RKKPK + EV + KS KK + K E SP K +K+E++ EVWKWWEEEK DGTKW FL+H+GP+FAP Y+ LP V FYYN K+ KLS + EEVA FYAR ++H+YT K+ FN NFF DWR+VMT ER IT+LSKC+F+E++ Y+ + SEERK +KEEK+ KEKN IQ E+G CVID H EKIGNF+IEPPGLFRGR +L + + + Q+++V S LK ++ YE AR+L I+KIR +Y D+KSKEMR+RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHI LH +DGK+Y V FDFLGKDSIRY+N VPVEKRVFKN+QLFMENK DDLFDRLNTT++N++LN LM+GLTAKVFRT+NAS+TLQ QL++LT+ +D K+LSYNRANR VAILCNHQR+ PKTH KSM+NL+ KI AK+EA + E +K AK+ K+ GS EKV +KKKK LER EQL KLE QA D+EENK IALGTSKLNYLDPRISVAW KK +VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct: 203 DKDRNLSKDKERENK--KHSSSGERDKDRHSTSHSSGDKEKHRSSEKDKDKHRESSSSSKDKQHRHEKDKDRHRHDKSKHRDEKEKRDKDKEEIKIKEETDMKLNHATNER--FH-YNLEVKPE-----IKEEPMTQLELDEDDDSGGERPLYIKEEDDDEEAVKEEASMDSTDGNDTRLSDLHNTTLKTEEDSEEDKPLSSRSKVSPSVKRKIESDEEEDVPLSARKKPKRATSSKTKKKKRKHDGENDDDSEVESEEKSKKKV-RAKGEGASPRK----RKQEEEQEVWKWWEEEKKSDGTKWHFLEHKGPVFAPPYEPLPPNVKFYYNGKETKLSQDAEEVATFYARMLDHDYTTKDAFNNNFFHDWREVMTESERAKITDLSKCNFKEMHAYFLQKSEERKAMTKEEKQKIKEKNDEIQKEYGFCVIDGHKEKIGNFKIEPPGLFRGRGEHPKMGKLKKRVLPEDVLINCSKDSNIPKPPAGHKWKEVRHDPNVTWLASWTE---NIQGQVKYVMLNPSSKLKGEKDWQKYETARKLAQSIDKIRAEYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHIKLHEQRDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKSPGDDLFDRLNTTVMNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTDPNDTEAEKILSYNRANRAVAILCNHQRSVPKTHAKSMENLKAKIDAKKEAIAECELQVKDAKRDAKH-GSVKEKVTYEKKKKQLERLKEQLTKLEVQATDREENKEIALGTSKLNYLDPRISVAWCKKHNVPIEKIYNKTQRDKFRWAIDMAGPDYVF 1038
BLAST of EMLSAG00000000293 vs. nr
Match: gi|350404638|ref|XP_003487171.1| (PREDICTED: DNA topoisomerase I, mitochondrial [Bombus impatiens]) HSP 1 Score: 721.079 bits (1860), Expect = 0.000e+0 Identity = 388/701 (55.35%), Postives = 492/701 (70.19%), Query Frame = 0
Query: 227 QQEQQVKDEPQYEEELHEEQDEFEEDRYNNAKQENME-VEVKVQDDSEDDIPLAKKS--KNKKRKSRDEDSEDDVPLSKRKKPKVKKVERVEVSKKSKSSKKNHKVKHEVVSPTKSGGR-----------KKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKY---------------------SKSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
+Q +K++ EE ++EE+ + N+ + ++ +K +++S++D+PL+ +S ++S D + EDDVPLS RKK K + + +K + + +++ + P K GGR KK+E++ EVWKWWEEEK +DGTKW FL+H+GP+FAP Y+ LP V FYY K+MKLS + EEVA FYAR ++H+YT K FN NFF DWR+VMT ER I +LSKC+F+E+++Y+ + SEERK +KEEK+ KE N IQ E+G C+ID H EKIGNF+IEPPGLFRGR +G + R+ K ++RH VK + K+K K + YE AR+L I+KIR +Y D+KSKEMR+RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLH KDGK+Y V FDFLGKDSIRY+N VPVEKRVFKN+QLFMENK DDLFDRLNTT++N++LN LM+GLTAKVFRT+NAS+TLQ QL++LT DD K+LSYNRANR VAILCNHQR+ PKTH KSM+NL+ KI+AK++A +AE +K+AK+ K+ GS EKVV +KKKKAL+R EQL KLE QA DKEENK IALGTSKLNYLDPRI+VAW KK +VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct: 332 EQPLYIKEDDDDEEAMNEEEGSMDSTDGNDTRLSDLHNTTIKTEEESDEDMPLSARSMAPTSVKRSLDSEEEDDVPLSARKKSKKNDTKAKKKKRKHEDDEDEDEIEQK---PKKKGGRASKGENSSPRKKKQEEEQEVWKWWEEEKKNDGTKWTFLEHKGPVFAPPYEPLPPDVKFYYCGKEMKLSQDAEEVATFYARMLDHDYTTKSAFNNNFFHDWREVMTESERAKINDLSKCNFKEMHSYFVQKSEERKAMTKEEKQKIKETNEQIQKEYGFCIIDGHKEKIGNFKIEPPGLFRGRGEHPKMGKLKRRVMPEDILINCSKDSNIPKPPPGHKWKEVRHDPNVTWLASWTENIQGQVKYVMLNPSSKLKGEKDWQKYETARKLAQLIDKIRAEYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKSPSDDLFDRLNTTVMNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTNPDDTEAEKILSYNRANRAVAILCNHQRSVPKTHAKSMENLKAKIEAKKQAISEAEHAVKEAKRDAKH-GSVKEKVVYEKKKKALDRLKEQLTKLEVQATDKEENKEIALGTSKLNYLDPRITVAWCKKHNVPIEKIYNKTQRDKFRWAIDMAGPDYVF 1028
BLAST of EMLSAG00000000293 vs. nr
Match: gi|987905862|ref|XP_015440538.1| (PREDICTED: DNA topoisomerase I, mitochondrial isoform X1 [Dufourea novaeangliae] >gi|1016159729|gb|KZC06891.1| DNA topoisomerase 1 [Dufourea novaeangliae]) HSP 1 Score: 720.694 bits (1859), Expect = 0.000e+0 Identity = 390/664 (58.73%), Postives = 476/664 (71.69%), Query Frame = 0
Query: 266 VKVQDDSEDDIPLAKKSK---NKKRKSRDEDSEDDVPLSKRKKPK-------VKKV------ERVEVSKKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR-----------------YLV-----GFMDRKYS--KSNQIRH-----------------VKSFL-----KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
+K +++S++D+PL+ +SK KR+ +D E+DVPL RKK K +KK E+VE K K S+ + K + SP K KK+E++ EVWKWWEEEK +DGTKW FL+H+GP+FAP Y+ LP V FYYN K+MKLS +TEEVA FYAR ++H+YT K FN NFF DWR+VMT ER I++L+KC+F+E++TY+ + SEERK +K+EK+ KE+N IQ E+G C ID H EKIGNF+IEPPGLFRGR L+ + + S K +IRH VK + K+K K + YE AR+L I+KIR +Y D+KSKEMR+RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLH KDGK+Y V FDFLGKDSIRY+N VPVEKRVFKN+QLFMENK DDLFDRLNTT++N++LN LM+GLTAKVFRT+NAS+TLQ QL++LT DD + K+LSYNRANR VAILCNHQR+ PKTH KSM+NL+ KI+AK+EA AE +K AK+ K+ GS EKVV +KKKK L+R EQL KLE QA DKEENK IALGTSKLNYLDPRISVAW KK DVPI+K+YNKTQRDKFRWAI+MAG DYVF
Sbjct: 374 IKTEEESDEDMPLSTRSKPNTTSKRRIYSDDEEEDVPLVVRKKSKKTETKAQIKKPKYEDEEEQVEQKPKKKRSRTS---KGDNTSPRK----KKQEEEQEVWKWWEEEKKNDGTKWTFLEHKGPVFAPSYEPLPPNVKFYYNGKEMKLSQDTEEVATFYARMLDHDYTTKPAFNSNFFHDWREVMTESERSKISDLNKCNFKEMHTYFLQKSEERKAMTKDEKQKIKEQNEEIQKEYGFCTIDGHKEKIGNFKIEPPGLFRGRGEHPKMGKLKKRVMPEDILINCSKDSCIPKPPSGHKWKEIRHDPNVTWLASWTENVQGQVKYVMLNPSSKLKGEKDWQKYETARKLAQSIDKIRAEYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHEQKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKSPGDDLFDRLNTTVMNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTNPDDTIAEKILSYNRANRAVAILCNHQRSVPKTHAKSMENLKAKIEAKKEAITDAELAVKDAKREAKH-GSVKEKVVYEKKKKTLDRLREQLTKLEVQATDKEENKEIALGTSKLNYLDPRISVAWCKKNDVPIDKIYNKTQRDKFRWAIDMAGPDYVF 1029
BLAST of EMLSAG00000000293 vs. nr
Match: gi|1134627525|ref|XP_019882816.1| (PREDICTED: DNA topoisomerase I, mitochondrial, partial [Camponotus floridanus]) HSP 1 Score: 720.309 bits (1858), Expect = 0.000e+0 Identity = 424/855 (49.59%), Postives = 548/855 (64.09%), Query Frame = 0
Query: 107 EEERKVRKEKERKEREERHKREGRRDE---TEDERRLRKERERKEREERHK-REGRREETEEERKARKEKEQRHKSKETEEERRVRKDKERAEKEARKRKEMGYDHSMGEEVSFHNHDEEMKMEQQEQQVKDEPQYEEELHEEQDEF--------EEDRYNNAKQENMEVE----------------VKVQDDSEDDIPLAKKSKNKKRKSR--DEDSEDDVPLSKRKKPKVKKV---------------ERVEVSKKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR-----------------------------------------------YLVGFMDRKYSKSNQIRHV----KSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
+++R + K+KER+ + +H G RD+ + KE+ R +++ K RE +++ + K+K++ K + + ++DK++ E + ++ +M +H+ E FH ++ E+K E +K+EP + EL E+ D EED A +E ++ +K ++DSE+D PL+ +SK R + D E+DVPLS RKKPK + EV + KS KK + K E SP K +K+E++ EVWKWWEEEK DGTKW FL+H+GP+FAP Y+ LP V FYYN K+ KLS + EEVA FYAR ++H+YT K+ FN NFF DWR+VMT ER IT+LSKC+F+E++ Y+ + SEERK +KEEK+ KEKN IQ E+G CVID H EKIGNF+IEPPGLFRGR +L + + + Q+++V S LK ++ YE AR+L I+KIR +Y D+KSKEMR+RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHI LH +DGK+Y V FDFLGKDSIRY+N VPVEKRVFKN+QLFMENK DDLFDRLNTT++N++LN LM+GLTAKVFRT+NAS+TLQ QL++LT+ +D K+LSYNRANR VAILCNHQR+ PKTH KSM+NL+ KI AK+EA + E +K AK+ K+ GS EKV +KKKK LER EQL KLE QA D+EENK IALGTSKLNYLDPRISVAW KK +VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct: 164 DKDRNLSKDKERENK--KHSSSGERDKDRHSTSHSSGDKEKHRSSEKDKDKHRESSSSSKDKQHRHEKDKDRHRHDKSKHRDEKEKRDKDKEEIKIKEETDMKLNHATNER--FH-YNLEVKPE-----IKEEPMTQLELDEDDDSGGERPLYIKEEDDDEEAVKEEASMDSTDGNDTRLSDLHNTTLKTEEDSEEDKPLSSRSKVSPSVKRKIESDEEEDVPLSARKKPKRATSSKTKKKKRKHDGENDDDSEVESEEKSKKKV-RAKGEGASPRK----RKQEEEQEVWKWWEEEKKSDGTKWHFLEHKGPVFAPPYEPLPPNVKFYYNGKETKLSQDAEEVATFYARMLDHDYTTKDAFNNNFFHDWREVMTESERAKITDLSKCNFKEMHAYFLQKSEERKAMTKEEKQKIKEKNDEIQKEYGFCVIDGHKEKIGNFKIEPPGLFRGRGEHPKMGKLKKRVLPEDVLINCSKDSNIPKPPAGHKWKEVRHDPNVTWLASWTE---NIQGQVKYVMLNPSSKLKGEKDWQKYETARKLAQSIDKIRAEYREDWKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHIKLHEQRDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLQLFMENKSPGDDLFDRLNTTVMNKHLNELMEGLTAKVFRTYNASWTLQQQLDKLTDPNDTEAEKILSYNRANRAVAILCNHQRSVPKTHAKSMENLKAKIDAKKEAIAECELQVKDAKRDAKH-GSVKEKVTYEKKKKQLERLKEQLTKLEVQATDREENKEIALGTSKLNYLDPRISVAWCKKHNVPIEKIYNKTQRDKFRWAIDMAGPDYVF 999
BLAST of EMLSAG00000000293 vs. nr
Match: gi|913304894|ref|XP_013182884.1| (PREDICTED: DNA topoisomerase I, mitochondrial isoform X3 [Amyelois transitella]) HSP 1 Score: 720.309 bits (1858), Expect = 0.000e+0 Identity = 403/720 (55.97%), Postives = 493/720 (68.47%), Query Frame = 0
Query: 222 EMKMEQQEQQVKDEPQYEEELHEEQDEFEEDRYNNAKQENMEV--------------EVKVQDDSEDDIPLAKKSKNKKRKSRDEDSEDDVPLSKRKKPKVKKVERVEV-----------SKKSKSSKKNHKVKHE---VVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYS---------------------KSNQIRH----------------------VKSFLKIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
E ++Q QV DEP + E+ EE ED Y M E+ ++DSE+DIPL ++ +KKR + +SE+D+PL +RKK K KKV++ + KK +K +K E VVSPTK +KK+E++ EVWKWWEEEK DDGTKW FL+H+GPLFAP Y+ LP V F Y+ K+++LS + EEVAGFYAR ++H+YT K+ FN NFF DWRKVMT+EE +ITNLSKCDF+E+ Y+ VSE+ KNR+KEEK A K KN IQ E+G C ID H EKIGNFRIEPPGLFRGR +G + R+ K ++RH + K+K K + YE AR+L I+KIRD Y D+K+KEMRVRQR+VALYFID+LALRAGNEKD+DQADTVGCCSLRVEHI LH KDG+++ V FDFLGKDSIRY+N V VEKRVFKN++LFMENK+ DDLFDRLNT LNE+L LM GLTAKVFRT+NAS TLQ QL+ELT+A ++P K+L+YNRANR VA+LCNHQRA PK H KSM+ L++KI+AKR+ E+AE+DLK A KA K GS EK++ DKKKKALER EQL KLE Q D++ENKTIALGTSKLNYLDPRISVAW KK VPIEK+YNKTQRDKFRWAI+MAG +YVF
Sbjct: 238 ESSVKQDPIQV-DEPVVKNEIKEEP----EDGYGGFNNTTMSSCDYNLSQFKDEPLSELPQEEDSEEDIPLLERMASKKRPA--SESEEDIPLLQRKKLKKKKVKKEPIYDDEEDEEIKPKKKKIKPEKRKSIKQEPDEVVSPTKK--KKKQEEEQEVWKWWEEEKKDDGTKWTFLEHKGPLFAPPYEPLPSNVKFRYDGKEVRLSQDAEEVAGFYARMLDHDYTTKDTFNNNFFADWRKVMTKEETKLITNLSKCDFKEMQAYFLSVSEKNKNRTKEEKAALKAKNEEIQKEYGFCTIDGHKEKIGNFRIEPPGLFRGRGEHPKMGMLKRRVMPEDVLINCSKDSKIPKPPAGHKWKEVRHDNTVTWLASWTENVQGQSKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRDTYRNDWKAKEMRVRQRAVALYFIDRLALRAGNEKDDDQADTVGCCSLRVEHIELHKEKDGQEHVVVFDFLGKDSIRYYNEVAVEKRVFKNLELFMENKKDSDDLFDRLNTQTLNEHLKELMPGLTAKVFRTYNASITLQRQLDELTDAKASIPEKILAYNRANRAVAVLCNHQRAVPKGHSKSMEALKEKIQAKRDQVEEAERDLKDATKAAKR-GSEKEKIICDKKKKALERLKEQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHGVPIEKIYNKTQRDKFRWAIDMAGPEYVF 947
BLAST of EMLSAG00000000293 vs. nr
Match: gi|646723372|gb|KDR24006.1| (DNA topoisomerase 1 [Zootermopsis nevadensis]) HSP 1 Score: 720.309 bits (1858), Expect = 0.000e+0 Identity = 400/706 (56.66%), Postives = 487/706 (68.98%), Query Frame = 0
Query: 227 QQEQQVKDEP-QYEEELHEEQDEFEEDRYNNAKQENMEVEVKVQDDSEDDIPL------------AKKSKNKKRKSRDEDSEDD-VPLSKRKKPKVKKVERVEVS-----KKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFM---------------DRKYSKSN------QIRHVKSFL----------------------KIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
Q +K+EP + E L +E + N K E ++KV++D EDDIPL A +S + K R EDS+DD VPL RKK K + ++ E S K K K VK E+ + +KK+E++ EVWKWWEEEK DDGTKWKFL+H+GP+FAP YDRLP + F+Y+ K+M LS TEEVA FYAR ++H+YT KE FN+NFFKDWRKVMT +E++ IT+LSKC+F++++ Y+ +EERK SKEEKK K++N I E+G CVID H E+IGNF+IEPPGLFRGR +G + D K K +IRH K+ K+K K + YE AR+L IEKIR +Y DFKSKEMR+RQR+VALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHI+LH+ KDGKDY V FDF GKDSIRY+N V VEKRVFKN+QLFM+NK DDLFDRLNTT+LN++LN LM+GLTAKVFRT+NASFTLQ+QL++LT+ D V K+L+YNRANR VAILCNHQRA PKTH KSM+NL+ KI AK+E + AE+ K K +K GS K+ M+K+KKALE+ EQL KLE QA DKEENK IAL TSKLNYLDPRISVAW KK +VPIEK+YNKTQRDKFRWAI+MAG DYVF
Sbjct: 256 QPMAWIKEEPVNHNERLVHSVNESGDQSSVNFKSETA-TKIKVEEDIEDDIPLWRSEDRAHRSGLASRSVVGEVKRRLEDSDDDDVPLMARKKIKKESKKQKEESDEEEFKPVKKKSKKGNVKEEITPQSSPRKKKKEEEQQEVWKWWEEEKKDDGTKWKFLEHKGPVFAPLYDRLPPDIKFFYDGKEMTLSEPTEEVASFYARMLDHDYTTKEAFNKNFFKDWRKVMTDKEKERITDLSKCNFKQMHKYFLAKAEERKAMSKEEKKKLKDQNEEIVKEYGFCVIDGHTERIGNFKIEPPGLFRGRGEHPKMGMLKKRVIPEDVIINCSKDSKIPKPPDGHKWREIRHDKNVTWLASWTENVQGQVKYVMLNPSSKLKGEKDWQKYETARKLAKCIEKIRQEYQDDFKSKEMRIRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHISLHSQKDGKDYVVVFDFPGKDSIRYYNEVSVEKRVFKNLQLFMQNKSTGDDLFDRLNTTVLNKHLNELMEGLTAKVFRTYNASFTLQEQLDKLTDPDYTVQEKILAYNRANRAVAILCNHQRAVPKTHAKSMENLKGKIDAKKEMVQDAERQYKDVKHEHKRNGSAKNKIDMEKRKKALEKLREQLAKLELQATDKEENKEIALSTSKLNYLDPRISVAWCKKHNVPIEKIYNKTQRDKFRWAIDMAGPDYVF 960
BLAST of EMLSAG00000000293 vs. nr
Match: gi|768417486|ref|XP_011549382.1| (PREDICTED: DNA topoisomerase I, mitochondrial [Plutella xylostella]) HSP 1 Score: 716.457 bits (1848), Expect = 0.000e+0 Identity = 385/655 (58.78%), Postives = 470/655 (71.76%), Query Frame = 0
Query: 271 DSEDDIPLAKKSKNKKRKSRDEDSEDDVPLSKRKKPKVKKVERV-----EVS------KKSKSSKKNHKVKHE-VVSPTKSGGRKKKEDKVEVWKWWEEEKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDR---------------------KYSKSNQIRH----------------------VKSFLKIKRGKGY--YEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
DSE+D PL ++ K+R + E SEDD PL+ RKKPK KK+++ E+S KK +K KVK E SPTK +KK++D+ EVWKWWEEEK DDGTKWKFL+H+GPLFAP Y+ +P+ V F Y+ K ++LS + EEVAGFYAR ++H+YT K VFN NFF DWRKVMT +E +I +L KCDF+E+ Y++ VSE+ KNR+KEEK K N IQ E+G C+ID H EKIGNFRIEPPGLFRGR +G + + K K ++RH + K+K K + YE AR+L I+KIRD Y D+K+KEMRVRQR+VALYFID+LALRAGNEKD+DQADTVGCCSLRVEHI LH KDGK+Y V FDFLGKDSIRY+N VPVEKRVFKN++LFMENK+ DDLFDRLNT LNE+L LM GLTAKVFRT+NAS TLQ QL+ELT+ D ++P K+L+YNRANR VA+LCNHQRA PK HDKSM+ L++KI+AKR+ ++AE+D++Q+ KA K GS EK+ DKK KALER +QL KLE Q D++ENKTIALGTSKLNYLDPRISVAW KK DVPIEK+YNKTQRDKFRWAI+MAG +YVF
Sbjct: 293 DSEEDTPLLERMAPKRRAVKSE-SEDDTPLTMRKKPKKKKIKKESGYDEEMSDDEPKAKKPTKTKPAAKVKTEDGPSPTKR--KKKQDDEPEVWKWWEEEKKDDGTKWKFLEHKGPLFAPPYEPIPENVKFRYDGKVVRLSQDAEEVAGFYARMLDHDYTTKSVFNNNFFADWRKVMTHDEAKLIKDLKKCDFKEMQAYFQSVSEKNKNRTKEEKAQLKATNEEIQKEYGFCIIDGHKEKIGNFRIEPPGLFRGRGEHPKMGMLKKRVMPEDVLINCSKDSNVPKPPKGHKWKEVRHDNTVTWLASWTENVQGQTKYVMLNPSSKLKGEKDWQKYETARKLHKCIDKIRDTYRSDWKAKEMRVRQRAVALYFIDRLALRAGNEKDDDQADTVGCCSLRVEHIALHKEKDGKEYVVVFDFLGKDSIRYYNEVPVEKRVFKNLELFMENKKDSDDLFDRLNTQTLNEHLKELMPGLTAKVFRTYNASITLQRQLDELTDGDASIPEKILAYNRANRAVAVLCNHQRAVPKGHDKSMEALKEKIQAKRDQIDEAEEDVRQSAKAAKR-GSVKEKMNHDKKTKALERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIYNKTQRDKFRWAIDMAGPEYVF 943
BLAST of EMLSAG00000000293 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold462_size163801-snap-gene-0.41 (protein:Tk04567 transcript:maker-scaffold462_size163801-snap-gene-0.41-mRNA-1 annotation:"topoisomerase 1b") HSP 1 Score: 806.594 bits (2082), Expect = 0.000e+0 Identity = 424/691 (61.36%), Postives = 501/691 (72.50%), Query Frame = 0
Query: 247 DEFEEDRYNNAKQENMEVEVKVQDDSEDDIPLAKKSKNKK------RKSRDEDSEDDVPLSKRKKPK----------------VKKVERVEVSKKSKSSKKNHKVKHEVVSPTKSGGRKKKEDKVEVWKWWEE--EKVDDGTKWKFLQHRGPLFAPDYDRLPKGVHFYYNDKKMKLSSETEEVAGFYARXIEHEYTEKEVFNRNFFKDWRKVMTREERDIITNLSKCDFREINTYYKKVSEERKNRSKEEKKAEKEKNAAIQDEFGICVIDNHNEKIGNFRIEPPGLFRGR---YLVGFMDRKYSK-----------------------------------------SNQIRHV----KSFLKIKRGKGYYEKARELKSKIEKIRDDYTVDFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHTVKDGKDYCVEFDFLGKDSIRYHNIVPVEKRVFKNVQLFMENKRGEDDLFDRLNTTILNEYLNSLMKGLTAKVFRTFNASFTLQDQLEELTEADDNVPAKMLSYNRANRKVAILCNHQRAAPKTHDKSMQNLQDKIKAKREAXEKAEKDLKQAKKAYKNGGSTSEKVVMDKKKKALERTVEQLDKLETQAVDKEENKTIALGTSKLNYLDPRISVAWSKKFDVPIEKVYNKTQRDKFRWAIEMAGADYVF 865
D+ +D + K+E M+ E DSE+D PLA+ SK +K D+D ++DVP++KRK+ K VK + + +K K + +P + G + KKE+ EVWKWWEE K DDGTKW+FL+H+GPLFAPDY+ LP VHFYY K+M+LS +TEEVA FY R ++H+YT KEVFNRN+ KDWRKVM +E++II ++SKCDF+EI ++KKVSEERK RSK+++KAEKE+N AIQ E+G C ID H EKIGNFRIEPP LFRGR G + ++ S NQI++V S LK ++ YEKARELK I KIRDDYT DFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLH KDG++Y VEFDFLGKDSIRY+N VPVEKRVFKNVQLFMENK+ DDLFDRLNT+ILNEYLN+LM GLTAKVFRT+NAS TLQ+QL +LTE DDNVPAKMLSYNRANR VA+LCNHQRA PKTH+KSM NLQ KI+ K++A KAEK+ K AKK++KNGGS + K+ MDKKKKALER +EQL+KLETQAVDKEENK+IALGTSKLNYLDPRISVAW KKFDVPIEKVYNKTQR+KFRWAIEMAG +Y F
Sbjct: 236 DDDSQDSQASMKEEPMDGE-----DSEEDKPLARNSKKRKVNDDEDEFQPDDDDDEDVPIAKRKRVKKEEPRYKEEDDDYQEDVKPAKSKKKAKPEKKTPSKPASSSASSNP-RGGKKVKKEENQEVWKWWEETTHKKDDGTKWQFLEHKGPLFAPDYEPLPSHVHFYYEGKRMRLSQDTEEVATFYGRMLDHDYTTKEVFNRNYMKDWRKVMNEKEKEIIRDISKCDFKEIGVHFKKVSEERKGRSKDDRKAEKERNEAIQKEYGFCTIDGHVEKIGNFRIEPPSLFRGRGEHPKQGMLKKRVSPEDVIINCSKNSDIPKPPEGRKWKKVQHDNTVTWLACWTENIQNQIKYVMLNPSSKLKGEKDMAKYEKARELKKLIHKIRDDYTADFKSKEMRVRQRSVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHITLHPEKDGQEYVVEFDFLGKDSIRYNNCVPVEKRVFKNVQLFMENKKAGDDLFDRLNTSILNEYLNTLMPGLTAKVFRTYNASITLQEQLNQLTEEDDNVPAKMLSYNRANRAVAVLCNHQRAVPKTHEKSMTNLQTKIEGKKDAVNKAEKEFKAAKKSHKNGGSATSKINMDKKKKALERLMEQLNKLETQAVDKEENKSIALGTSKLNYLDPRISVAWCKKFDVPIEKVYNKTQREKFRWAIEMAGPEYQF 920 The following BLAST results are available for this feature:
BLAST of EMLSAG00000000293 vs. GO
Analysis Date: 2014-04-02 (Blast vs. GO) Total hits: 25
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BLAST of EMLSAG00000000293 vs. C. finmarchicus
Analysis Date: 2014-05-09 (TblastN vs C. finmarchicus TSA) Total hits: 7
BLAST of EMLSAG00000000293 vs. L. salmonis peptides
Analysis Date: 2014-05-10 (Blastp vs. self) Total hits: 1
BLAST of EMLSAG00000000293 vs. SwissProt
Analysis Date: 2017-02-10 (Blastp vs. SwissProt) Total hits: 22
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BLAST of EMLSAG00000000293 vs. Select Arthropod Genomes
Analysis Date: 2017-02-20 (Blastp vs. Selected Arthropods) Total hits: 24
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BLAST of EMLSAG00000000293 vs. nr
Analysis Date: 2017-02-20 (Blastp vs. NR (2/2017)) Total hits: 25
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BLAST of EMLSAG00000000293 vs. Tigriopus kingsejongenis genes
Analysis Date: 2018-04-18 (Blastp vs. Tigriopus kingsejongensis proteins) Total hits: 1
Alignments
The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Cross References
External references for this gene
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at LSalAtl2s1044:15439..19815- Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>EMLSAG00000000293-683059 ID=EMLSAG00000000293-683059|Name=EMLSAG00000000293|organism=Lepeophtheirus salmonis|type=gene|length=4377bp|location=Sequence derived from alignment at LSalAtl2s1044:15439..19815- (Lepeophtheirus salmonis)back to top Add to Basket
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