EMLSAG00000003780, EMLSAG00000003780-686546 (gene) Lepeophtheirus salmonis
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Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of EMLSAG00000003780 vs. GO
Match: - (symbol:Top3a "topoisomerase (DNA) III alpha" species:10090 "Mus musculus" [GO:0000166 "nucleotide binding" evidence=IEA] [GO:0003676 "nucleic acid binding" evidence=IEA] [GO:0003677 "DNA binding" evidence=IEA] [GO:0003916 "DNA topoisomerase activity" evidence=IEA] [GO:0003917 "DNA topoisomerase type I activity" evidence=ISO] [GO:0005524 "ATP binding" evidence=IEA] [GO:0005694 "chromosome" evidence=IEA] [GO:0006265 "DNA topological change" evidence=ISO] [GO:0008270 "zinc ion binding" evidence=IEA] [GO:0016605 "PML body" evidence=ISO] [GO:0016853 "isomerase activity" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] InterPro:IPR000380 InterPro:IPR001878 InterPro:IPR003601 InterPro:IPR003602 InterPro:IPR010666 InterPro:IPR013497 InterPro:IPR013498 InterPro:IPR013824 InterPro:IPR013826 InterPro:IPR023406 Pfam:PF01131 Pfam:PF01396 Pfam:PF06839 PRINTS:PR00417 PROSITE:PS00396 SMART:SM00343 SMART:SM00436 SMART:SM00437 Pfam:PF01751 MGI:MGI:1197527 InterPro:IPR006171 GO:GO:0005524 GO:GO:0005694 GO:GO:0005654 GO:GO:0003677 GO:GO:0016605 GO:GO:0008270 Reactome:REACT_198624 Reactome:REACT_27235 SMART:SM00493 PROSITE:PS50880 GO:GO:0006265 GO:GO:0003917 Gene3D:3.40.50.140 Gene3D:1.10.460.10 InterPro:IPR023405 PANTHER:PTHR11390 SUPFAM:SSF56712 eggNOG:COG0550 KO:K03165 OrthoDB:EOG74R1Q0 Gene3D:1.10.290.10 CTD:7156 HOGENOM:HOG000184377 HOVERGEN:HBG056668 OMA:LYQICME TreeFam:TF105287 EMBL:AB006074 PIR:T13951 RefSeq:NP_033436.1 UniGene:Mm.477819 ProteinModelPortal:O70157 SMR:O70157 BioGrid:204278 IntAct:O70157 PhosphoSite:O70157 PaxDb:O70157 PRIDE:O70157 Ensembl:ENSMUST00000002891 GeneID:21975 KEGG:mmu:21975 UCSC:uc007jgl.1 InParanoid:O70157 NextBio:301678 PRO:PR:O70157 ArrayExpress:O70157 Bgee:O70157 CleanEx:MM_TOP3A Genevestigator:O70157 Uniprot:O70157) HSP 1 Score: 647.506 bits (1669), Expect = 0.000e+0 Identity = 369/767 (48.11%), Postives = 455/767 (59.32%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPS-LAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG-------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGL-QDNRFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRDSNDEGFF-SMSNESRFTPTLSQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSSAXIPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRF-------FYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPSTSSFNSN-------SQPAIN--------------------DENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGN 724
+KTLERE +C+ L+IWTD DREGENIGFEI VC V P L+VLRA+FSEIT ++ A LTEPD++ S AVDVRQ+LDLRIGAAFTRFQTLRL + FP LAEQLISYGSCQFPT+GFVVER+KAI+AFVPE F KIK VTH++++ VEF+WKR RLF+ A V + +C E+P+A V + +SKPKSKWRP LDTVELEKLASRKL I+AK TM+ AEKLYT G+ISYPRTETNI+PK+LNL LVE QT P WG G++ +LYEFIVRHFLA S+DA G+ETTV IDI E+F+ HG IL RNYL VYPY+ WSDK + YE F+P+++++V G TSPP LLTEADLI+LM+KHGIGTDATHAEHIETIK R YVGL D RF+PG LG+ L +GYD+MG+EMSKP LR+ LEADLK ICEG K VL++Q+ YK VF AV +K+DEA +YL E + E + +M R P +C D+ V+K + G C P C W + L +S N C V + K GS C + E F + S + + ++ + N SQP +N + NS+TCNCG A+ TV K+GPN+GR F+ C SN C FF W D +SHS G
Sbjct: 130 KKTLERETHHCQALVIWTDCDREGENIGFEIIHVCKAVKPNLRVLRARFSEITPHAVRTACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFPEVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPEVFHKIK-VTHDHKDGTVEFNWKRYRLFNHTACLVLYQLCMEDPMATVVEVRSKPKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYISYPRTETNIFPKDLNLVALVEQQTVDPHWGAFAQTILERGGPTPRNGSKSDQAHPPIHPTKYTSGLQGDDRRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLIILARNYLDVYPYDHWSDKLLPVYEQGSHFQPSTVEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVGLTSDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICEGKKDKFQVLRQQVQKYKQVFIEAVAKAKKLDEALSQYLGERTEMAQQEEIYPAMPEPVRKCP------QCNKDM------VLKTKKSGGFYLSCMGFP-----ECRSAVWFPDSVL----------EASRDNSVCSVCQPPPVYRLKLKFKRGSLPPAMPLEFVGCIGGCDETLKEIFGLRFPRALPRASQPSGHLQASQALNRMDSSQHNLSQPLVNRHTRPSKTVAQALLPPTTAGESNSVTCNCGREAVLLTVRKQGPNQGRHFYKC-----SNGDCNFFLWAD---SSHSTGGG 860 HSP 2 Score: 133.265 bits (334), Expect = 1.367e-30 Identity = 81/233 (34.76%), Postives = 113/233 (48.50%), Query Frame = 0
Query: 575 PLPSSSSAXIPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPSTSSFNSNSQPAI----------------NDENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGNFN-----GNDSNFRRPSRDSTVPSRGGGGGLKRSGSTTREGGSDKKKRRCGLCHREGHTRNKCPNNR 786
P + + A +P ++ +S+TCNCG+ A TV+K+G N+GR FY C CNFF WA S TP+++S S + + C CG A+ +TV K+GPNKGR+F C+KP ++C FF+W DE + PG+F G +RP S P R+GS+ G + KK R+C LCH+ GHTR CP NR
Sbjct: 793 PSKTVAQALLPPTTA-GESNSVTCNCGREAVLLTVRKQGPNQGRHFYKC-----SNGDCNFFLWADSSHSTGGGTPTSASGPPGSSVGCPSSVGSHMDGFGSLGSDSDGGTPCLCGQPAVTRTVQKDGPNKGRQFHTCAKP--REQQCGFFQWVDE----NVAPGSFAAPAWPGGRGKAQRPEAASKRP---------RAGSSD-AGSTVKKPRKCSLCHQPGHTRTFCPQNR 1003 HSP 3 Score: 75.8702 bits (185), Expect = 1.105e-12 Identity = 49/138 (35.51%), Postives = 64/138 (46.38%), Query Frame = 0
Query: 525 SQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDE--------------PP-----LPSSSSAXIPSNSSLSNXS--SITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXE 641
S ++ C C A TV K+GPN+GR FY C+ C+FF W D PP PSS + + SL + S C CG+ A RTVQK+G NKGR F++C +C FF+W E
Sbjct: 810 SNSVTCNCGREAVLLTVRKQGPNQGRHFYKCS-----NGDCNFFLWADSSHSTGGGTPTSASGPPGSSVGCPSSVGSHMDGFGSLGSDSDGGTPCLCGQPAVTRTVQKDGPNKGRQFHTC--AKPREQQCGFFQWVDE 940 HSP 4 Score: 55.4546 bits (132), Expect = 2.048e-6 Identity = 31/77 (40.26%), Postives = 42/77 (54.55%), Query Frame = 0
Query: 506 SNDEGFFSMSNESRFTPTLSQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSSA 582
S+ +GF S+ ++S C C A +TV K+GPNKGR+F+ C P +C FFQWVDE P S +A
Sbjct: 881 SHMDGFGSLGSDS------DGGTPCLCGQPAVTRTVQKDGPNKGRQFHTCAKPRE--QQCGFFQWVDENVAPGSFAA 949
BLAST of EMLSAG00000003780 vs. GO
Match: - (symbol:TOP3A "DNA topoisomerase" species:9615 "Canis lupus familiaris" [GO:0003677 "DNA binding" evidence=IEA] [GO:0003917 "DNA topoisomerase type I activity" evidence=IEA] [GO:0005694 "chromosome" evidence=IEA] [GO:0006265 "DNA topological change" evidence=IEA] [GO:0008270 "zinc ion binding" evidence=IEA] [GO:0016605 "PML body" evidence=IEA] InterPro:IPR000380 InterPro:IPR001878 InterPro:IPR003601 InterPro:IPR003602 InterPro:IPR010666 InterPro:IPR013497 InterPro:IPR013498 InterPro:IPR013824 InterPro:IPR013825 InterPro:IPR023406 Pfam:PF01131 Pfam:PF01396 Pfam:PF06839 PRINTS:PR00417 PROSITE:PS00396 SMART:SM00343 SMART:SM00436 SMART:SM00437 Pfam:PF01751 InterPro:IPR006171 GO:GO:0005694 GO:GO:0003677 GO:GO:0016605 GO:GO:0008270 SMART:SM00493 PROSITE:PS50880 GO:GO:0006265 GO:GO:0003917 Gene3D:3.40.50.140 Gene3D:1.10.460.10 Gene3D:2.70.20.10 InterPro:IPR023405 PANTHER:PTHR11390 SUPFAM:SSF56712 GeneTree:ENSGT00530000063430 KO:K03165 OrthoDB:EOG74R1Q0 CTD:7156 OMA:LYQICME TreeFam:TF105287 EMBL:AAEX03003715 RefSeq:XP_546656.2 Ensembl:ENSCAFT00000029019 GeneID:489537 KEGG:cfa:489537 NextBio:20862709 Uniprot:E2RIS5) HSP 1 Score: 645.966 bits (1665), Expect = 0.000e+0 Identity = 363/742 (48.92%), Postives = 448/742 (60.38%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPS-LAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG-------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGL-QDNRFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRDSNDEGFFSMSNESRFTPTLSQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSS---------------------AXIPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPSTSSFNSNSQPAINDENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTD 713
+KTL+RE C+ L+IWTD DREGENIGFEI VC V P L+VLRA+FSEIT ++ A LTEPD++ S AVDVRQ+LDLRIGAAFTRFQTLRL K FP LAEQLISYGSCQFPT+GFVVER+KAI+AFVPE F KIK VTH++++ VEF+WKR RLF+ A V + +C E+P A V + +SK KSKWRP LDTVELEKLASRKL I+AK TM+ AEKLYT G+ISYPRTETNI+PK+L+L+ LVE QT P+WG G+E +LYEFIVRHFLA S+DA G+ETTV IDI E+F+ HG IL RNYL VYPY+RWSDK + YE F+P+++++V G TSPP LLTEADLI+LM+KHGIGTDATHAEHIETIK R YVGL D RF+PG LG+ L +GYD+MG+EMSKP LR+ LEADLK ICEG K VVL++Q+ YK VF AV +K+DEA +Y E + E + P++ + IK KC + V+K N G C +G C W + L +S +P L + C G R + ++G S P + N+ + S N T S A + NS+ CNCG A+ TV KEGPN+GR+F+ C C FF W D
Sbjct: 130 KKTLQRETQQCQALVIWTDCDREGENIGFEIIHVCRAVKPNLQVLRARFSEITPRAVRVACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQKIFPEVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPEIFHKIK-VTHDHKDGIVEFNWKRHRLFNHTACLVLYQLCMEDPTATVVEVRSKSKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYISYPRTETNIFPKDLDLTVLVEQQTPDPRWGAFAQSILERGGPTPRNGNKSDQAHPPIHPTKYTSSLQGDEQRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLMILARNYLDVYPYDRWSDKTLPVYERGSHFQPSTVEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVGLTADKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICEGKKDKSVVLRQQVQKYKQVFIEAVAKAKKLDEALSQYFGEGTEVAQQEAIY---------PSMPEPIK-KCPQ-CNKDMVLKTKKNGGFYLSC-----TGFPECRSAVWFPDSVLEASRDDSVCPVCQPHPVYRLKLKFKRGSLPPTMPL---EFVGCIGGCDETLREILDLRFSRGPPRASQPASQPS----NYL----QASQSQNRTDSAPRMLPLPAAADGESNSVICNCGQEAVLLTVRKEGPNQGRQFYKC-----GGGGCDFFLWAD 838 HSP 2 Score: 119.783 bits (299), Expect = 2.288e-26 Identity = 81/235 (34.47%), Postives = 108/235 (45.96%), Query Frame = 0
Query: 575 PLPSSSSAXIPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPSTSSFNS-----NSQPAINDENS------------LTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGNFNGNDSNFRRPSRDSTVPSRGGG---GGLKRS----GSTTREGGSDKKKRRCGLCHREGHTRNKCPNN 785
PLP+++ +S+ CNCG+ A TV+KEG N+GR FY C G C+FF WA + S+ P S+ PA+ D + C C A+ +TV K+GPNKGR+F C+KP ++C FF+W DE + PG R T P RG G G RS S+ G + KK R+C LCH+ GHTR CP N
Sbjct: 787 PLPAAADG---------ESNSVICNCGQEAVLLTVRKEGPNQGRQFYKC-----GGGGCDFFLWA-DSSALEPRGPPASALGPAGGSLGHPPAMGDRRGGFGRPGDDGGRGMACLCSQPAVTRTVQKDGPNKGRQFHTCAKP--REQQCGFFQWVDE----NVAPGTL-----------RTPTWP-RGRGRTQGPEARSKRARASSADMGSTPKKPRKCSLCHQPGHTRPFCPQN 988 HSP 3 Score: 80.4925 bits (197), Expect = 4.108e-14 Identity = 54/150 (36.00%), Postives = 71/150 (47.33%), Query Frame = 0
Query: 525 SQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVD----EPPLPSSSSAXIPSNSSLSNXSS------------------ITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXE-VSSFNNNTPS 651
S ++ C C A TV KEGPN+GR+FY C G CDFF W D EP P +SA P+ SL + + + C C + A RTVQK+G NKGR F++C +C FF+W E V+ TP+
Sbjct: 796 SNSVICNCGQEAVLLTVRKEGPNQGRQFYKC-----GGGGCDFFLWADSSALEPRGP-PASALGPAGGSLGHPPAMGDRRGGFGRPGDDGGRGMACLCSQPAVTRTVQKDGPNKGRQFHTC--AKPREQQCGFFQWVDENVAPGTLRTPT 937
BLAST of EMLSAG00000003780 vs. GO
Match: - (symbol:TOP3A "DNA topoisomerase" species:9606 "Homo sapiens" [GO:0003677 "DNA binding" evidence=IEA] [GO:0003917 "DNA topoisomerase type I activity" evidence=IEA] [GO:0005694 "chromosome" evidence=IEA] [GO:0006265 "DNA topological change" evidence=IEA] [GO:0008270 "zinc ion binding" evidence=IEA] InterPro:IPR000380 InterPro:IPR001878 InterPro:IPR003601 InterPro:IPR003602 InterPro:IPR010666 InterPro:IPR013497 InterPro:IPR013498 InterPro:IPR013824 InterPro:IPR013825 InterPro:IPR023406 Pfam:PF01131 Pfam:PF01396 Pfam:PF06839 PRINTS:PR00417 PROSITE:PS00396 SMART:SM00343 SMART:SM00436 SMART:SM00437 Pfam:PF01751 InterPro:IPR006171 GO:GO:0005694 GO:GO:0003677 GO:GO:0008270 SMART:SM00493 PROSITE:PS50880 GO:GO:0006265 EMBL:AC127537 GO:GO:0003917 Gene3D:3.40.50.140 Gene3D:1.10.460.10 Gene3D:2.70.20.10 InterPro:IPR023405 PANTHER:PTHR11390 SUPFAM:SSF56712 KO:K03165 UniGene:Hs.592115 GeneID:7156 KEGG:hsa:7156 CTD:7156 HGNC:HGNC:11992 HOVERGEN:HBG056668 EMBL:AK296437 RefSeq:XP_005256833.1 ProteinModelPortal:B4DK80 SMR:B4DK80 Ensembl:ENST00000542570 UCSC:uc010vxs.1 NextBio:35472722 ArrayExpress:B4DK80 Uniprot:B4DK80) HSP 1 Score: 639.032 bits (1647), Expect = 0.000e+0 Identity = 377/809 (46.60%), Postives = 468/809 (57.85%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPS-LAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG-------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQ-DNRFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRDSNDEGFFSMSNESRFTPTLSQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSSAXIPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPV-----------NMAEGSRCNFFKWAXEVSSFNNNTPSTSSFN-----SNSQPA--------------------INDENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGNFNGNDSNFRRPSRDSTVPSRGGG---GGLKRSGSTTREGGS 762
+KTLERE C+ L+IWTD DREGENIGFEI VC V P L+VLRA+FSEIT ++ A LTEPD++ S AVDVRQ+LDLRIGAAFTRFQTLRL + FP LAEQLISYGSCQFPT+GFVVER+KAI+AFVPE F +IK VTH++++ VEF+WKR RLF+ A V + +C E+P+A V + +SKPKSKWRP LDTVELEKLASRKL I+AK TM+ AEKLYT G+ISYPRTETNI+P++LNL+ LVE QT P+WG G+E +LYEFIVRHFLA S+DA G+ETTV IDI E+F+ HG IL RNYL VYPY+ WSDK + YE F+P+++++V G TSPP LLTEADLI+LM+KHGIGTDATHAEHIETIK R YVGL D RF+PG LG+ L +GYD+MG+EMSKP LR+ LEADLK IC+G K VVL++Q+ YK VF AV +K+DEA +Y + E + E + + +C D+ V+K N G C P C W+ + L +S SS+ C YR K +G + P+ + E F S + + S N + QPA + NS+TCNCG A+ TV KEGPN+GR+F+ C+ GS C FF W D NPG G + RP S G G GG G + G S
Sbjct: 35 KKTLERETRQCQALVIWTDCDREGENIGFEIIHVCKAVKPNLQVLRARFSEITPHAVRTACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFPEVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPEIFHRIK-VTHDHKDGIVEFNWKRHRLFNHTACLVLYQLCVEDPMATVVEVRSKPKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYISYPRTETNIFPRDLNLTVLVEQQTPDPRWGAFAQSILERGGPTPRNGNKSDQAHPPIHPTKYTNNLQGDEQRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLMILARNYLDVYPYDHWSDKILPVYEQGSHFQPSTVEMVDGETSPPKLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVGLTPDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICDGKKDKFVVLRQQVQKYKQVFIEAVAKAKKLDEALAQYFGNGTELAQQEDIYPAMPEP-----IRKCPQCNKDM------VLKTKKNGGFYLSCMGFP-----ECRSAVWLPDSVLEASRD------------SSVCPVCQPHPVYRL--KLKFKRGSLPPTMPLEFVCCIGGCDDTLREILDLRFSGGPPRASQPSGRLQANQSLNRMDNSQHPQPADSRQTGSSKALAQTLPPPTAAGESNSVTCNCGQEAVLLTVRKEGPNRGRQFFKCNG--GS---CNFFLWADS-----PNPGA-GGPPALAYRPLGASLGCPPGPGIHLGGFGNPGDGSGSGTS 801 HSP 2 Score: 120.168 bits (300), Expect = 1.646e-26 Identity = 72/220 (32.73%), Postives = 104/220 (47.27%), Query Frame = 0
Query: 584 IPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPST------SSFNSNSQPAIN----------DENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTN-SHSNPGNFNGNDSNFRRPSRDSTVPSRGGGGGLKRSGSTTREGGSDKKKRRCGLCHREGHTRNKCPNNR 786
+P ++ +S+TCNCG+ A TV+KEG N+GR F+ C G CNFF WA + P+ +S P I+ + +C C ++ +TV K+GPNKGR+F C+KP ++C FF+W DE T S ++ G+ S P S++ G + KK R+C LCH+ GHTR CP NR
Sbjct: 704 LPPPTAAGESNSVTCNCGQEAVLLTVRKEGPNRGRQFFKC-----NGGSCNFFLWADSPNPGAGGPPALAYRPLGASLGCPPGPGIHLGGFGNPGDGSGSGTSCLCSQPSVTRTVQKDGPNKGRQFHTCAKP--REQQCGFFQWVDENTAPGTSGAPSWTGDRGRTLESEARSKRP----------RASSSDMGSTAKKPRKCSLCHQPGHTRPFCPQNR 906 HSP 3 Score: 78.1814 bits (191), Expect = 2.085e-13 Identity = 58/179 (32.40%), Postives = 76/179 (42.46%), Query Frame = 0
Query: 503 PRDSNDEGFFSMSNESRFTPTL---SQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDE-------PPL----PSSSSAXIP----------SNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPSTSSFNS 657
P DS G ++ PT S ++ C C A TV KEGPN+GR+F+ CN C+FF W D PP P +S P N + S +C C + + RTVQK+G NKGR F++C +C FF+W E N P TS S
Sbjct: 688 PADSRQTGSSKALAQTLPPPTAAGESNSVTCNCGQEAVLLTVRKEGPNRGRQFFKCN-----GGSCNFFLWADSPNPGAGGPPALAYRPLGASLGCPPGPGIHLGGFGNPGDGSGSGTSCLCSQPSVTRTVQKDGPNKGRQFHTC--AKPREQQCGFFQWVDE-----NTAPGTSGAPS 854
BLAST of EMLSAG00000003780 vs. GO
Match: - (symbol:TOP3A "DNA topoisomerase 3-alpha" species:9606 "Homo sapiens" [GO:0003677 "DNA binding" evidence=IEA] [GO:0003917 "DNA topoisomerase type I activity" evidence=IDA] [GO:0005515 "protein binding" evidence=IPI] [GO:0005524 "ATP binding" evidence=IEA] [GO:0005634 "nucleus" evidence=TAS] [GO:0005694 "chromosome" evidence=IEA] [GO:0006265 "DNA topological change" evidence=IDA] [GO:0007126 "meiotic nuclear division" evidence=TAS] [GO:0008270 "zinc ion binding" evidence=IEA] [GO:0016605 "PML body" evidence=IDA] InterPro:IPR000380 InterPro:IPR001878 InterPro:IPR003601 InterPro:IPR003602 InterPro:IPR010666 InterPro:IPR013497 InterPro:IPR013498 InterPro:IPR013824 InterPro:IPR013825 InterPro:IPR023406 Pfam:PF01131 Pfam:PF01396 Pfam:PF06839 PRINTS:PR00417 PROSITE:PS00396 SMART:SM00343 SMART:SM00436 SMART:SM00437 Pfam:PF01751 InterPro:IPR006171 GO:GO:0005524 GO:GO:0007126 GO:GO:0005694 GO:GO:0003677 GO:GO:0016605 GO:GO:0008270 Reactome:REACT_111183 EMBL:CH471196 SMART:SM00493 PROSITE:PS50880 GO:GO:0006265 GO:GO:0003917 Gene3D:3.40.50.140 Gene3D:1.10.460.10 Gene3D:2.70.20.10 InterPro:IPR023405 PANTHER:PTHR11390 SUPFAM:SSF56712 eggNOG:COG0550 KO:K03165 OrthoDB:EOG74R1Q0 EMBL:U43431 EMBL:HQ205026 EMBL:HQ205027 EMBL:HQ205028 EMBL:HQ205029 EMBL:HQ205030 EMBL:HQ205031 EMBL:HQ205032 EMBL:HQ205033 EMBL:HQ205034 EMBL:HQ205035 EMBL:HQ205036 EMBL:HQ205037 EMBL:HQ205038 EMBL:HQ205039 EMBL:HQ205040 EMBL:HQ205041 EMBL:HQ205042 EMBL:HQ205043 EMBL:HQ205044 EMBL:HQ205045 EMBL:HQ205046 EMBL:HQ205047 EMBL:HQ205048 EMBL:HQ205049 EMBL:HQ205050 EMBL:HQ205051 EMBL:HQ205052 EMBL:HQ205053 EMBL:HQ205054 EMBL:HQ205055 EMBL:HQ205056 EMBL:HQ205057 EMBL:HQ205058 EMBL:HQ205059 EMBL:HQ205060 EMBL:HQ205061 EMBL:HQ205062 EMBL:HQ205063 EMBL:HQ205064 EMBL:HQ205065 EMBL:AK292926 EMBL:BC051748 RefSeq:NP_004609.1 UniGene:Hs.592115 ProteinModelPortal:Q13472 SMR:Q13472 BioGrid:113009 DIP:DIP-33323N IntAct:Q13472 MINT:MINT-6610291 STRING:9606.ENSP00000321636 PhosphoSite:Q13472 DMDM:2501242 PaxDb:Q13472 PRIDE:Q13472 Ensembl:ENST00000321105 Ensembl:ENST00000580095 GeneID:7156 KEGG:hsa:7156 UCSC:uc002gsx.1 CTD:7156 GeneCards:GC17M018175 HGNC:HGNC:11992 HPA:CAB002449 HPA:HPA042910 MIM:601243 neXtProt:NX_Q13472 PharmGKB:PA36673 HOGENOM:HOG000184377 HOVERGEN:HBG056668 InParanoid:Q13472 OMA:LYQICME PhylomeDB:Q13472 TreeFam:TF105287 GeneWiki:TOP3A GenomeRNAi:7156 NextBio:28002 PRO:PR:Q13472 ArrayExpress:Q13472 Bgee:Q13472 CleanEx:HS_TOP3A Genevestigator:Q13472 Uniprot:Q13472) HSP 1 Score: 639.032 bits (1647), Expect = 0.000e+0 Identity = 366/767 (47.72%), Postives = 455/767 (59.32%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPS-LAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG-------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQ-DNRFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRDSNDEGFFSMSNESRFTPTLSQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSSAXIPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPV-----------NMAEGSRCNFFKWAXEVSSFNNNTPSTSSFN-----SNSQPA--------------------INDENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPG 723
+KTLERE C+ L+IWTD DREGENIGFEI VC V P L+VLRA+FSEIT ++ A LTEPD++ S AVDVRQ+LDLRIGAAFTRFQTLRL + FP LAEQLISYGSCQFPT+GFVVER+KAI+AFVPE F +IK VTH++++ VEF+WKR RLF+ A V + +C E+P+A V + +SKPKSKWRP LDTVELEKLASRKL I+AK TM+ AEKLYT G+ISYPRTETNI+P++LNL+ LVE QT P+WG G+E +LYEFIVRHFLA S+DA G+ETTV IDI E+F+ HG IL RNYL VYPY+ WSDK + YE F+P+++++V G TSPP LLTEADLI+LM+KHGIGTDATHAEHIETIK R YVGL D RF+PG LG+ L +GYD+MG+EMSKP LR+ LEADLK IC+G K VVL++Q+ YK VF AV +K+DEA +Y + E + E + + +C D+ V+K N G C P C W+ + L +S SS+ C YR K +G + P+ + E F S + + S N + QPA + NS+TCNCG A+ TV KEGPN+GR+F+ C+ GS C FF W D NPG
Sbjct: 130 KKTLERETRQCQALVIWTDCDREGENIGFEIIHVCKAVKPNLQVLRARFSEITPHAVRTACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFPEVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPEIFHRIK-VTHDHKDGIVEFNWKRHRLFNHTACLVLYQLCVEDPMATVVEVRSKPKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYISYPRTETNIFPRDLNLTVLVEQQTPDPRWGAFAQSILERGGPTPRNGNKSDQAHPPIHPTKYTNNLQGDEQRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLMILARNYLDVYPYDHWSDKILPVYEQGSHFQPSTVEMVDGETSPPKLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVGLTPDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICDGKKDKFVVLRQQVQKYKQVFIEAVAKAKKLDEALAQYFGNGTELAQQEDIYPAMPEP-----IRKCPQCNKDM------VLKTKKNGGFYLSCMGFP-----ECRSAVWLPDSVLEASRD------------SSVCPVCQPHPVYRL--KLKFKRGSLPPTMPLEFVCCIGGCDDTLREILDLRFSGGPPRASQPSGRLQANQSLNRMDNSQHPQPADSRQTGSSKALAQTLPPPTAAGESNSVTCNCGQEAVLLTVRKEGPNRGRQFFKCNG--GS---CNFFLWADS-----PNPG 855 HSP 2 Score: 120.168 bits (300), Expect = 1.681e-26 Identity = 72/220 (32.73%), Postives = 104/220 (47.27%), Query Frame = 0
Query: 584 IPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPST------SSFNSNSQPAIN----------DENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTN-SHSNPGNFNGNDSNFRRPSRDSTVPSRGGGGGLKRSGSTTREGGSDKKKRRCGLCHREGHTRNKCPNNR 786
+P ++ +S+TCNCG+ A TV+KEG N+GR F+ C G CNFF WA + P+ +S P I+ + +C C ++ +TV K+GPNKGR+F C+KP ++C FF+W DE T S ++ G+ S P S++ G + KK R+C LCH+ GHTR CP NR
Sbjct: 799 LPPPTAAGESNSVTCNCGQEAVLLTVRKEGPNRGRQFFKC-----NGGSCNFFLWADSPNPGAGGPPALAYRPLGASLGCPPGPGIHLGGFGNPGDGSGSGTSCLCSQPSVTRTVQKDGPNKGRQFHTCAKP--REQQCGFFQWVDENTAPGTSGAPSWTGDRGRTLESEARSKRP----------RASSSDMGSTAKKPRKCSLCHQPGHTRPFCPQNR 1001 HSP 3 Score: 78.1814 bits (191), Expect = 2.155e-13 Identity = 57/175 (32.57%), Postives = 75/175 (42.86%), Query Frame = 0
Query: 503 PRDSNDEGFFSMSNESRFTPTL---SQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDE-------PPL----PSSSSAXIP----------SNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPSTS 653
P DS G ++ PT S ++ C C A TV KEGPN+GR+F+ CN C+FF W D PP P +S P N + S +C C + + RTVQK+G NKGR F++C +C FF+W E N P TS
Sbjct: 783 PADSRQTGSSKALAQTLPPPTAAGESNSVTCNCGQEAVLLTVRKEGPNRGRQFFKCN-----GGSCNFFLWADSPNPGAGGPPALAYRPLGASLGCPPGPGIHLGGFGNPGDGSGSGTSCLCSQPSVTRTVQKDGPNKGRQFHTC--AKPREQQCGFFQWVDE-----NTAPGTS 945 HSP 4 Score: 53.9138 bits (128), Expect = 5.887e-6 Identity = 25/53 (47.17%), Postives = 32/53 (60.38%), Query Frame = 0
Query: 530 CKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSSA 582
C C + +TV K+GPNKGR+F+ C P +C FFQWVDE P +S A
Sbjct: 897 CLCSQPSVTRTVQKDGPNKGRQFHTCAKPRE--QQCGFFQWVDENTAPGTSGA 947
BLAST of EMLSAG00000003780 vs. GO
Match: - (symbol:TOP3A "DNA topoisomerase" species:9031 "Gallus gallus" [GO:0003677 "DNA binding" evidence=IEA] [GO:0003917 "DNA topoisomerase type I activity" evidence=IEA] [GO:0005694 "chromosome" evidence=IEA] [GO:0006265 "DNA topological change" evidence=IEA] [GO:0008270 "zinc ion binding" evidence=IEA] [GO:0016605 "PML body" evidence=IEA] InterPro:IPR000380 InterPro:IPR001878 InterPro:IPR003601 InterPro:IPR003602 InterPro:IPR010666 InterPro:IPR013497 InterPro:IPR013498 InterPro:IPR013824 InterPro:IPR013826 InterPro:IPR023406 Pfam:PF01131 Pfam:PF01396 Pfam:PF06839 PRINTS:PR00417 PROSITE:PS00396 SMART:SM00343 SMART:SM00436 SMART:SM00437 Pfam:PF01751 InterPro:IPR006171 GO:GO:0005694 GO:GO:0003677 GO:GO:0016605 GO:GO:0008270 SMART:SM00493 PROSITE:PS50880 GO:GO:0006265 GO:GO:0003917 Gene3D:3.40.50.140 Gene3D:1.10.460.10 InterPro:IPR023405 PANTHER:PTHR11390 SUPFAM:SSF56712 GeneTree:ENSGT00530000063430 OrthoDB:EOG74R1Q0 Gene3D:1.10.290.10 TreeFam:TF105287 OMA:SCMDKAG EMBL:AADN03006925 Ensembl:ENSGALT00000008050 PRO:PR:F1P1F3 Uniprot:F1P1F3) HSP 1 Score: 627.861 bits (1618), Expect = 0.000e+0 Identity = 315/510 (61.76%), Postives = 373/510 (73.14%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPS-LAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG-------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGL-QDNRFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNES 502
++TLERE C+ L+IWTD DREGENIGFEI VC V P L+V RA+FSEIT ++ A LT+PD+K S AV+VRQ+LDLRIGAAFTRFQTLRL K FP LA+QLISYGSCQFPT+GFVVER+KAI+AFVPEAF+KIK VTH++E+ V F+WKR RLF+ A V + +C E+PVA V + SKPKSKWRPLPLDTVELEKLASRKL I+AK TM+ AEKLYT GFISYPRTETNI+PKELNLS LV+ QTQ P WG GNE +LYEFIVRHFLA S+DA G+ETTV IDI E+F+ G IL RNYL+VYPYE+WSDK I Y+ F+PT++++V G TSPP LLTEADLI+LM+KHGIGTDATHAEHIETIK R YVGL D RF+PG LG+ L +GYD+MG+EMSKP LR+ LEADLK ICEG K +VL +Q+ YK VF AV K+D+A +Y E+
Sbjct: 132 KRTLEREVQQCQALVIWTDCDREGENIGFEIIHVCKAVKPNLQVFRARFSEITLHAVRRACENLTQPDQKTSDAVEVRQELDLRIGAAFTRFQTLRLQKIFPDILADQLISYGSCQFPTLGFVVERFKAIQAFVPEAFYKIK-VTHDHEDGNVVFNWKRNRLFNHTACLVLYHMCMEDPVATVVEVGSKPKSKWRPLPLDTVELEKLASRKLKINAKETMRIAEKLYTQGFISYPRTETNIFPKELNLSALVQHQTQDPNWGAFAQRILDQGGPTPRNGTKSDQAHPPIHPTKYTANLQGNEQRLYEFIVRHFLACCSQDAKGQETTVEIDIANERFVAQGLMILARNYLEVYPYEKWSDKVIPLYQKGSRFQPTTVEMVDGETSPPLLLTEADLIALMEKHGIGTDATHAEHIETIKTRMYVGLTADQRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICEGKKDKSIVLHQQVQKYKQVFIEAVARANKLDQALAQYFGEA 640 HSP 2 Score: 112.079 bits (279), Expect = 6.635e-24 Identity = 73/213 (34.27%), Postives = 98/213 (46.01%), Query Frame = 0
Query: 594 SSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPSTSSFNSNSQPAINDENS-----------------------LTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGNFNGNDSNFRRPSRDSTVPSRGGGGGLKRSGSTTREGGSDKKKRRCGLCHREGHTRNKCP 783
+++ CNCG A TV+KEG N+GR FY C N CNFF W+ + S +N S + A NS C C A+ +TV K+GPNKGR+F CSKP ++C FF+W DE ++ G+F+ N S+ SR G KR S G + KK R C +CH+ GHT+ CP
Sbjct: 821 NAVVCNCGNEAMLLTVRKEGPNQGRQFYKCSANT-----CNFFLWSDQQSEDRSNAAPRGSAPPRAFGARGPANSQRPGGKRGPEHFGSSNNSSSGDSTVCRCDQPAVTRTVQKDGPNKGRQFHTCSKP--REQQCGFFQWADENVAPGAS-GDFSFNHFG-------SSEYSRELGSKAKRP-SNLSHGATAKKPRTCSICHQPGHTKKTCP 1017 HSP 3 Score: 73.1738 bits (178), Expect = 7.112e-12 Identity = 50/143 (34.97%), Postives = 66/143 (46.15%), Query Frame = 0
Query: 527 TIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDE------------PPLPSSSSAXIPSNSS----------------LSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXE 641
+ C C A TV KEGPN+GR+FY C+ AN C+FF W D+ P + A P+NS S+ S C C + A RTVQK+G NKGR F++C + +C FF+WA E
Sbjct: 822 AVVCNCGNEAMLLTVRKEGPNQGRQFYKCS-----ANTCNFFLWSDQQSEDRSNAAPRGSAPPRAFGARGPANSQRPGGKRGPEHFGSSNNSSSGDSTVCRCDQPAVTRTVQKDGPNKGRQFHTC--SKPREQQCGFFQWADE 957 HSP 4 Score: 56.9954 bits (136), Expect = 7.464e-7 Identity = 25/51 (49.02%), Postives = 33/51 (64.71%), Query Frame = 0
Query: 530 CKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSS 580
C+CD A +TV K+GPNKGR+F+ C+ P +C FFQW DE P +S
Sbjct: 916 CRCDQPAVTRTVQKDGPNKGRQFHTCSKPRE--QQCGFFQWADENVAPGAS 964
BLAST of EMLSAG00000003780 vs. GO
Match: - (symbol:TOP3A "DNA topoisomerase" species:9913 "Bos taurus" [GO:0003677 "DNA binding" evidence=IEA] [GO:0003917 "DNA topoisomerase type I activity" evidence=IEA] [GO:0005694 "chromosome" evidence=IEA] [GO:0006265 "DNA topological change" evidence=IEA] [GO:0008270 "zinc ion binding" evidence=IEA] [GO:0016605 "PML body" evidence=IEA] InterPro:IPR000380 InterPro:IPR001878 InterPro:IPR003601 InterPro:IPR003602 InterPro:IPR010666 InterPro:IPR013497 InterPro:IPR013498 InterPro:IPR013824 InterPro:IPR013825 InterPro:IPR023406 Pfam:PF01131 Pfam:PF01396 Pfam:PF06839 PRINTS:PR00417 PROSITE:PS00396 SMART:SM00343 SMART:SM00436 SMART:SM00437 Pfam:PF01751 InterPro:IPR006171 GO:GO:0005694 GO:GO:0003677 GO:GO:0016605 GO:GO:0008270 SMART:SM00493 PROSITE:PS50880 GO:GO:0006265 GO:GO:0003917 Gene3D:3.40.50.140 Gene3D:1.10.460.10 Gene3D:2.70.20.10 InterPro:IPR023405 PANTHER:PTHR11390 SUPFAM:SSF56712 GeneTree:ENSGT00530000063430 OrthoDB:EOG74R1Q0 OMA:LYQICME TreeFam:TF105287 EMBL:DAAA02048987 EMBL:DAAA02048988 Ensembl:ENSBTAT00000022721 Uniprot:F1MGY1) HSP 1 Score: 613.224 bits (1580), Expect = 0.000e+0 Identity = 313/539 (58.07%), Postives = 379/539 (70.32%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPS-LAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG-------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQ-DNRFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRDSNDEGFFSMSNESRFTPTLSQTIKCK 531
+KTLEREA C+ L+IWTD DREGENIGFE+ VC V P L+VLRA+FSEIT ++ A LTEPD++ S AVDVRQ+LDLRIGAAFTRFQTLRL K FP LAEQLISYGSCQFPT+GFVVER+KAI+AFVPE F KI+ VTH++ + VEFSWKR RLF+ A V + +C E+P A V + +SK KSKWRP LDTVELEKLASRKL I+AK TM+ AEKLYT G+ISYPRTETNI+PK+L+L+ LVE QT P+WG G+E +LYE IVRHFLA S+DA G+ETTV IDI E+F+ HG IL RNYL VYPY+RWSDK + YE F+P+++++V G TSPP LLTEADLI+LM+KHGIGTDATHAEHIETIK R YVGL D RF+PG LG+ L +GYD+MG+EMSKP LR+ LEADLK ICEG K VVL +Q+ YK VF AV +K+DEA +Y + + + ++ R P S+ + K
Sbjct: 130 KKTLEREAQQCQALVIWTDCDREGENIGFEVIHVCKAVKPSLQVLRARFSEITTRAVRTACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQKIFPEVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPEVFHKIR-VTHDHRDGVVEFSWKRHRLFNHTACLVLYQMCMEDPRAMVVEVRSKAKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYISYPRTETNIFPKDLDLAALVEQQTPDPRWGAFARNILERGGPTPRNGNKSDQAHPPIHPTKYTDSLQGDEQRLYELIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLMILARNYLDVYPYDRWSDKTLPVYEQGTCFQPSTVEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVGLTPDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICEGKKDKLVVLHQQVQKYKQVFIEAVAKARKLDEALSQYFGAATEVAPQDALPAVPEPIRKCPQCSRDMVLK 667 HSP 2 Score: 126.331 bits (316), Expect = 2.001e-28 Identity = 87/239 (36.40%), Postives = 111/239 (46.44%), Query Frame = 0
Query: 574 PPLPSSSSA---XIPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPSTSSFNSNSQPAINDENSLT-----------------CNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGNFNGNDSNFRRPSRDSTVP-SRGGGGGLKRSGSTTREGGSD-----KKKRRCGLCHREGHTRNKCPNNR 786
PP+ S A +P + S +S+TCNCG+ A TV+KEG N+GR FY C G C+FF WA S P +S+ P + S T C CG A+ +TV KEGPN+GR+F C++P +C FF+W DE + PG F G P SR G GL+ R G SD KK R+C LCH+ GHTR CP NR
Sbjct: 788 PPVTRPSKALTRTLPPPAVESESNSVTCNCGQEALLLTVRKEGPNQGRQFYKC----GSGG-CSFFLWAD--SGHPGAGPPSSASRPPGGPLEHPPGSGTLLGGSSRPGSGGSGGASCLCGQPAVTRTVQKEGPNQGRQFHTCAQP--REHQCGFFQWVDE----NVAPGTFGG-----------PLWPGSRRGTQGLEARSKRPRAGSSDTGSAAKKPRKCSLCHQPGHTRPFCPQNR 1002 HSP 3 Score: 78.1814 bits (191), Expect = 1.896e-13 Identity = 49/137 (35.77%), Postives = 62/137 (45.26%), Query Frame = 0
Query: 525 SQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVD--EPPLPSSSSAXIPSNSSLSN------------------XSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXE 641
S ++ C C A TV KEGPN+GR+FY C G+ C FF W D P SSA P L + +C CG+ A RTVQKEG N+GR F++C +C FF+W E
Sbjct: 810 SNSVTCNCGQEALLLTVRKEGPNQGRQFYKC-----GSGGCSFFLWADSGHPGAGPPSSASRPPGGPLEHPPGSGTLLGGSSRPGSGGSGGASCLCGQPAVTRTVQKEGPNQGRQFHTC--AQPREHQCGFFQWVDE 939
BLAST of EMLSAG00000003780 vs. GO
Match: - (symbol:Top3a "topoisomerase (DNA) III alpha" species:10116 "Rattus norvegicus" [GO:0003677 "DNA binding" evidence=IEA] [GO:0003917 "DNA topoisomerase type I activity" evidence=IEA;ISO] [GO:0005694 "chromosome" evidence=IEA] [GO:0006265 "DNA topological change" evidence=IEA;ISO] [GO:0008270 "zinc ion binding" evidence=IEA] [GO:0016605 "PML body" evidence=IEA;ISO] InterPro:IPR000380 InterPro:IPR001878 InterPro:IPR003601 InterPro:IPR003602 InterPro:IPR010666 InterPro:IPR013497 InterPro:IPR013498 InterPro:IPR013824 InterPro:IPR013825 Pfam:PF01131 Pfam:PF01396 Pfam:PF06839 PRINTS:PR00417 SMART:SM00343 SMART:SM00436 SMART:SM00437 Pfam:PF01751 RGD:1309320 InterPro:IPR006171 GO:GO:0005694 GO:GO:0003677 GO:GO:0016605 GO:GO:0008270 SMART:SM00493 PROSITE:PS50880 GO:GO:0006265 GO:GO:0003917 Gene3D:3.40.50.140 Gene3D:1.10.460.10 Gene3D:2.70.20.10 InterPro:IPR023405 PANTHER:PTHR11390 SUPFAM:SSF56712 GeneTree:ENSGT00530000063430 OrthoDB:EOG74R1Q0 OMA:SCMDKAG EMBL:AABR06064113 EMBL:AABR06064111 EMBL:AABR06064112 Ensembl:ENSRNOT00000068351 UCSC:RGD:1309320 NextBio:35572933 Uniprot:D4A6J4) HSP 1 Score: 603.594 bits (1555), Expect = 0.000e+0 Identity = 359/787 (45.62%), Postives = 449/787 (57.05%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPS-LAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNL--------------------------VEMQTQSPQ-----------WGGNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGL-QDNRFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRDSNDEGFF-SMSNESRFTPTLSQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSSAXIPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPV-----------NMAEGSRCNFFKWAXEVSSFNNNTPSTSSFN-------SNSQPAIN--------------------DENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEV--------TNSHSNPGNFNGNDSNF 732
+KTLERE +C+ L+IWTD DREGENIGFEI VC V P L+VLRA+FSEIT ++ A LTEPD++ S AVDVRQ+LDLRIGAAFTRFQTLRL + FP LAEQLISYGSCQFPT+GFVVER+KAI+AFVPE F +IK VTH++++ VEF+WKR RLF+ A V + +C E+P+A V + +SKPKSKWRP LDTVELEKLASRKL I+AK TM+ AEKLYT G P + P + LS+L E QT Q G++ +LYEFIVRHFLA S+DA G+ETTV IDI E+F+ HG IL RNYL VYPY+ WSDK + YE F+P+++++V G TSPP LLTEADLI+LM+KHGIGTDATHAEHIETIK R YVGL D RF+PG LG+ L +GYD+MG+EMSKP+LR+ LEADLK ICEG K VL++Q+ YK VF AV +K+DEA +YL E + E + +M R P +C D+ V+K + G C P C W + L + S SS+ C YR K +G S P+ + E F + S + + ++ + N S SQP +N + NS+TCNCG A+ TV K+GPN+GR F+ C S C FF W D T+ PGN G S F
Sbjct: 130 KKTLERETQHCQALVIWTDCDREGENIGFEIIHVCKAVKPNLQVLRARFSEITHHAVRAACEHLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFPEVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPEVFHRIK-VTHDHKDGTVEFNWKRYRLFNHTACLVLYQLCMEDPMATVVEVRSKPKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGVSQQPAHLGIVLPDGVLLSDLNSIPSTHIHSGSLPSLTSIPGDPMLTSERQTDGTQIPIHPTKYTSSLQGDDRRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLIILARNYLDVYPYDHWSDKLLPVYEQGFRFQPSTVEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVGLTSDKRFLPGHLGMGLVEGYDSMGYEMSKPNLRAELEADLKLICEGKKDKFQVLRQQVQKYKQVFIEAVAKAKKLDEALSQYLGERTEVAQQEEIYPAMPEPVRKCP------QCNKDM------VLKTKKSGGFYLSCTGFP-----ECRSAVWFPDSVLEA------------SRDSSVCSVCQPAPVYRL--KLKFKRGSLPPSMPLEFVGCIGGCDETLKEIFGLRFSRAPPRASQPSGHLQASQALNRMDSSQRSLSQPLVNRHTGPSKAVAQTLLPPTAAAEGNSVTCNCGREAVLLTVRKQGPNQGRHFYKC-----SGGDCNFFLWADSSHPTGGGPPTSVSRPPGNSVGCPSGF 879 HSP 2 Score: 126.716 bits (317), Expect = 1.699e-28 Identity = 77/220 (35.00%), Postives = 108/220 (49.09%), Query Frame = 0
Query: 588 SSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPST------------SSFNSN----SQPAINDENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGNFN-----GNDSNFRRPSRDSTVPSRGGGGGLKRSGSTTREGGSDKKKRRCGLCHREGHTRNKCPNNR 786
++ + +S+TCNCG+ A TV+K+G N+GR FY C G CNFF WA P++ S F S+ + + +C CG A+ +TV K+GPNKGR+F C+KP ++C FF+W DE + PG+F G +RP S +R+GS G + KK R+C LCH+ GHTR CP NR
Sbjct: 805 TAAAEGNSVTCNCGREAVLLTVRKQGPNQGRHFYKC-----SGGDCNFFLWADSSHPTGGGPPTSVSRPPGNSVGCPSGFGSHMDGFGSLGGDGDGGASCLCGQPAVTRTVQKDGPNKGRQFHTCAKP--REQQCGFFQWVDE----NMAPGSFAAPAWPGGRGKAQRPEAASK---------RQRAGSLD-AGSTVKKPRKCSLCHQPGHTRPFCPQNR 1003 HSP 3 Score: 54.299 bits (129), Expect = 4.967e-6 Identity = 26/53 (49.06%), Postives = 32/53 (60.38%), Query Frame = 0
Query: 530 CKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSSA 582
C C A +TV K+GPNKGR+F+ C P +C FFQWVDE P S +A
Sbjct: 899 CLCGQPAVTRTVQKDGPNKGRQFHTCAKPRE--QQCGFFQWVDENMAPGSFAA 949
BLAST of EMLSAG00000003780 vs. GO
Match: - (symbol:top3a "topoisomerase (DNA) III alpha" species:7955 "Danio rerio" [GO:0003676 "nucleic acid binding" evidence=IEA] [GO:0003677 "DNA binding" evidence=IEA] [GO:0003916 "DNA topoisomerase activity" evidence=IEA] [GO:0003917 "DNA topoisomerase type I activity" evidence=IEA] [GO:0006265 "DNA topological change" evidence=IEA] [GO:0005694 "chromosome" evidence=IEA] [GO:0008270 "zinc ion binding" evidence=IEA] [GO:0016853 "isomerase activity" evidence=IEA] InterPro:IPR000380 InterPro:IPR001878 InterPro:IPR003601 InterPro:IPR003602 InterPro:IPR010666 InterPro:IPR013497 InterPro:IPR013498 InterPro:IPR013824 InterPro:IPR013826 InterPro:IPR023406 Pfam:PF01131 Pfam:PF01396 Pfam:PF06839 PRINTS:PR00417 PROSITE:PS00396 SMART:SM00343 SMART:SM00436 SMART:SM00437 Pfam:PF01751 InterPro:IPR006171 ZFIN:ZDB-GENE-071212-2 GO:GO:0005694 GO:GO:0003677 GO:GO:0008270 SMART:SM00493 PROSITE:PS50880 GO:GO:0006265 GO:GO:0003917 Gene3D:3.40.50.140 Gene3D:1.10.460.10 InterPro:IPR023405 PANTHER:PTHR11390 SUPFAM:SSF56712 GeneTree:ENSGT00530000063430 OrthoDB:EOG74R1Q0 Gene3D:1.10.290.10 TreeFam:TF105287 OMA:SCMDKAG EMBL:BX649547 EMBL:BX649440 ProteinModelPortal:F1R242 Ensembl:ENSDART00000102492 Bgee:F1R242 Uniprot:F1R242) HSP 1 Score: 597.045 bits (1538), Expect = 0.000e+0 Identity = 305/507 (60.16%), Postives = 362/507 (71.40%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFP-SLAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG-------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGL-QDNRFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYL 499
++TLERE C+ LI+WTD DREGENIGFEI +VC V P ++V RA+FSEIT SI A LTEPD S AVDVRQ+LDLRIGA+FTRFQTLRL K FP SL++QLISYGSCQFPT+GFVVER+KAI+AF+PE F+KIK V E VEF+WKR RLF+ A V + +C E P+AKV SKPKSKWRPLPLDTVELEKLASRKL ISAK TM+ AEKLYT GFISYPRTETN++P+ LNL+ LVE QTQ +WG GNE +LYEFIVRHFLA SKDA G+E TV IDI E+F G TI+ RNYL+VYPY++W +K I +Y F+PT+I++V G TSPP LLTEADLISLM+KHGIGTDATHAEHIETIK+R YVGL D RF+PG+LG+ L +GY++MG+EMSKP LR+ LEADLK + EG K VL + YK VF +V+ +K+DEA YL
Sbjct: 127 KRTLEREVRQCQALIVWTDCDREGENIGFEIIDVCKAVKPNIQVFRARFSEITPNSIRRACETLTEPDINVSDAVDVRQELDLRIGASFTRFQTLRLQKIFPESLSDQLISYGSCQFPTLGFVVERFKAIQAFIPETFFKIKVVHEPNEEESVEFNWKRHRLFNHTACLVLYQMCMEEPMAKVISVTSKPKSKWRPLPLDTVELEKLASRKLRISAKETMKIAEKLYTQGFISYPRTETNMFPQNLNLTRLVEQQTQDQEWGNFAQRILESGGPTPRNGNKSDQAHPPIHPTKYTNGLQGNEKRLYEFIVRHFLACCSKDAQGQEVTVEIDIAEERFSASGLTIIARNYLEVYPYDKWYNKVIPSYSPNTTFQPTAIEMVEGQTSPPQLLTEADLISLMEKHGIGTDATHAEHIETIKSRMYVGLTADQRFLPGELGMGLVEGYNSMGYEMSKPDLRAELEADLKLVSEGRKNKASVLSYHVAKYKAVFIESVRKAKKLDEALSNYL 633 HSP 2 Score: 114.005 bits (284), Expect = 1.378e-24 Identity = 77/212 (36.32%), Postives = 105/212 (49.53%), Query Frame = 0
Query: 595 SITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVS------------SFNNNTPSTSS-FNSNSQPAIN------DENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGNFNGNDSNFRRPSRDSTVPSRGGGG---GLKRSGSTTREGGSDKKKRRCGLCHREGHTRNKCPN 784
+I CNCG+ A TV+KEG N+GR FY C N + C FF WA + S N P S+ F + SQ N DE CNC ++ +TV KEGPNKGR F C KP +++C FF+W +E + PG + +T S G GG G K++ +T+ + + K++R CG+CH GHTR CP
Sbjct: 812 AIVCNCGQDALLLTVRKEGPNQGRQFYKC--NTGD---CKFFLWADQPPEQGVPERNRGPLSQNVQPPRPSNGFGNVSQQRQNHRGSGGDEGETMCNCNEPSVTRTVMKEGPNKGRMFHTCGKP--RDQQCGFFQWANE----NVAPGMLTRFVGKY-----IATAFSGGNGGKPSGNKKASTTSVKPPTAKRQRTCGICHEPGHTRVTCPQ 1007 HSP 3 Score: 81.6481 bits (200), Expect = 1.660e-14 Identity = 51/143 (35.66%), Postives = 64/143 (44.76%), Query Frame = 0
Query: 523 TLSQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPP---LPSSSSAXI--------PSN-------------SSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXE 641
T I C C A TV KEGPN+GR+FY CN C FF W D+PP +P + + PSN S + CNC + + RTV KEG NKGR F++C +C FF+WA E
Sbjct: 808 TQGGAIVCNCGQDALLLTVRKEGPNQGRQFYKCN-----TGDCKFFLWADQPPEQGVPERNRGPLSQNVQPPRPSNGFGNVSQQRQNHRGSGGDEGETMCNCNEPSVTRTVMKEGPNKGRMFHTC--GKPRDQQCGFFQWANE 943 HSP 4 Score: 50.8322 bits (120), Expect = 5.264e-5 Identity = 28/74 (37.84%), Postives = 39/74 (52.70%), Query Frame = 0
Query: 501 ESPRDSNDEGFFSMSNES-RFTPTLSQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDE 573
+ PR SN G S ++ R + C C+ + +TV+KEGPNKGR F+ C P +C FFQW +E
Sbjct: 872 QPPRPSNGFGNVSQQRQNHRGSGGDEGETMCNCNEPSVTRTVMKEGPNKGRMFHTCGKPRD--QQCGFFQWANE 943
BLAST of EMLSAG00000003780 vs. GO
Match: - (symbol:Top3alpha "Topoisomerase 3alpha" species:7227 "Drosophila melanogaster" [GO:0003917 "DNA topoisomerase type I activity" evidence=ISS;NAS] [GO:0005694 "chromosome" evidence=IEA] [GO:0006265 "DNA topological change" evidence=IEA] [GO:0003677 "DNA binding" evidence=IEA] [GO:0008270 "zinc ion binding" evidence=IEA] [GO:0003916 "DNA topoisomerase activity" evidence=IDA] [GO:0000724 "double-strand break repair via homologous recombination" evidence=IMP] [GO:0000002 "mitochondrial genome maintenance" evidence=IMP] [GO:0005634 "nucleus" evidence=IDA] [GO:0005739 "mitochondrion" evidence=IDA] [GO:0042246 "tissue regeneration" evidence=IMP] [GO:0048589 "developmental growth" evidence=IMP] InterPro:IPR000380 InterPro:IPR001878 InterPro:IPR003601 InterPro:IPR003602 InterPro:IPR010666 InterPro:IPR013497 InterPro:IPR013498 InterPro:IPR013824 InterPro:IPR013826 InterPro:IPR023406 Pfam:PF01131 Pfam:PF01396 Pfam:PF06839 PRINTS:PR00417 PROSITE:PS00396 SMART:SM00343 SMART:SM00436 SMART:SM00437 Pfam:PF01751 InterPro:IPR006171 GO:GO:0005739 GO:GO:0005524 GO:GO:0005634 GO:GO:0005694 EMBL:AE014134 GO:GO:0003677 GO:GO:0008270 GO:GO:0000002 GO:GO:0042246 GO:GO:0000724 SMART:SM00493 PROSITE:PS50880 GO:GO:0006265 GO:GO:0003917 GO:GO:0003916 Gene3D:3.40.50.140 Gene3D:1.10.460.10 InterPro:IPR023405 PANTHER:PTHR11390 SUPFAM:SSF56712 EMBL:AF255733 EMBL:BT015282 RefSeq:NP_523602.2 UniGene:Dm.2659 ProteinModelPortal:Q9NG98 STRING:7227.FBpp0080787 PaxDb:Q9NG98 PRIDE:Q9NG98 EnsemblMetazoa:FBtr0081246 GeneID:35236 KEGG:dme:Dmel_CG10123 CTD:35236 FlyBase:FBgn0040268 eggNOG:COG0550 GeneTree:ENSGT00530000063430 InParanoid:Q9NG98 KO:K03165 OMA:LVIHERN OrthoDB:EOG74R1Q0 PhylomeDB:Q9NG98 GenomeRNAi:35236 NextBio:792526 PRO:PR:Q9NG98 Bgee:Q9NG98 Gene3D:1.10.290.10 Uniprot:Q9NG98) HSP 1 Score: 547.354 bits (1409), Expect = 2.924e-176 Identity = 279/512 (54.49%), Postives = 341/512 (66.60%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFP-SLAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTE--NPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQDNRF-VPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESP 503
++TLERE C+ LIIWTD DREGENIG+EI +VC + P + V RA FSEIT ++ AL+ L +PD++QS AVDVR +LDLR GAA TRFQT+RL + FP +A++LISYGSCQ PT+GFV ERYK IEAFV E FWKIK V H ++ VEF+W R RLFD+ A + Y +C +P A VE KPK KWRP PLDTVE+EKL SRKL +SAK TM AEKLYT GFISYPRTETN + KE L+ LVEMQT WG GNE ++YE +VRHFLA VSKDA+G ET V IDI GEKF +G I ERNYL VY Y++WS K+I +YE + FEPT + L G+T+ P LLTEADLI+LM+KHGIGTDATHAEHI TIK R Y+G+ D F VPG +G+ L +GYDAM ++KP LR+ E DLK IC+G K P+VVL EQI YK ++ + +D +NE+P
Sbjct: 122 KRTLEREVRGCQGLIIWTDCDREGENIGYEIIDVCRAIKPNISVYRATFSEITTVAVRRALQQLGQPDKRQSDAVDVRTELDLRTGAAITRFQTMRLQRLFPEKIADKLISYGSCQIPTLGFVAERYKEIEAFVSEPFWKIK-VLHTIDDLTVEFNWARNRLFDKEACENYLLLCLAEPDPRALVESVTVKPKHKWRPTPLDTVEMEKLGSRKLKLSAKETMTIAEKLYTKGFISYPRTETNQFSKEFALAPLVEMQTGHRDWGAFAQRVIEWGPNPRNGNKSDQAHPPIHPTKLAENLQGNEARVYELVVRHFLACVSKDAVGSETLVHIDIAGEKFTANGLVIHERNYLDVYVYDKWSAKQIHHYENGQRFEPTEVSLHEGATTAPPLLTEADLIALMEKHGIGTDATHAEHINTIKERGYIGVLDKGFLVPGVIGMGLYEGYDAMELALAKPQLRAEFELDLKLICQGQKDPKVVLTEQIAKYKQAYQQITDKITAMDAKISARINETP 632 HSP 2 Score: 106.686 bits (265), Expect = 3.762e-22 Identity = 78/244 (31.97%), Postives = 106/244 (43.44%), Query Frame = 0
Query: 588 SSLSNXSSITCN-CGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSF---NNNT----PSTSSFNSN---SQPAINDENS-------------------------------------LTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGNFNGNDSNFRRPSRDSTVPSRGGGGGLKRSGSTTREGGSDKKKRRCGLCHREGHTRNKCP 783
SS+ ++ C C + A TV+K G N GR +Y CP + CNFF+WA E S N+T ST+S+ SN + P+I NS + CNCG LA + TV K+GPN+GR F+ C + C FFKW DE N ++ ++ + N S+ + + S G K RRCGLC +EGHTRNKCP
Sbjct: 1025 SSVPESETVLCTGCQQPARQNTVRKNGPNLGRLYYKCP----KPDECNFFQWADEPPSSAKSKNSTGSAPQSTTSWGSNRVVTLPSIQQSNSQRGQSSMRSNSSSTVTITQTKTKQQERNTATPGDGEEVMCNCGQLASQLTVRKDGPNQGRPFYACPT---REKSCGFFKWGDEDQNQGASSTSWGSANRNPPGRSQPTAITSDG------------------PKTRRCGLCRKEGHTRNKCP 1243 HSP 3 Score: 48.9062 bits (115), Expect = 1.920e-4 Identity = 34/108 (31.48%), Postives = 50/108 (46.30%), Query Frame = 0
Query: 521 TPTLSQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSSAXIPSNS----SLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCP 624
TP + + C C A++ TV K+GPN+GR FY C + C FF+W DE +SS S + S ++IT + K +KEG + + CP
Sbjct: 1143 TPGDGEEVMCNCGQLASQLTVRKDGPNQGRPFYACP---TREKSCGFFKWGDEDQNQGASSTSWGSANRNPPGRSQPTAITSDGPKTRRCGLCRKEGHTRNK----CP 1243
BLAST of EMLSAG00000003780 vs. GO
Match: - (symbol:top-3 species:6239 "Caenorhabditis elegans" [GO:0007126 "meiotic nuclear division" evidence=IMP] [GO:0007276 "gamete generation" evidence=IMP] [GO:0048477 "oogenesis" evidence=IMP] InterPro:IPR000380 InterPro:IPR003601 InterPro:IPR003602 InterPro:IPR010666 InterPro:IPR013497 InterPro:IPR013824 InterPro:IPR013826 InterPro:IPR023406 Pfam:PF01131 Pfam:PF06839 PRINTS:PR00417 PROSITE:PS00396 SMART:SM00436 SMART:SM00437 Pfam:PF01751 InterPro:IPR006171 GO:GO:0005524 GO:GO:0005694 GO:GO:0003677 GO:GO:0008270 EMBL:AL132860 SMART:SM00493 PROSITE:PS50880 GO:GO:0006265 GO:GO:0003917 Gene3D:3.40.50.140 Gene3D:1.10.460.10 InterPro:IPR023405 PANTHER:PTHR11390 SUPFAM:SSF56712 eggNOG:COG0550 GeneTree:ENSGT00530000063430 KO:K03165 Gene3D:1.10.290.10 HOGENOM:HOG000184377 EMBL:AF057032 PIR:T43031 RefSeq:NP_499558.1 UniGene:Cel.19512 ProteinModelPortal:O61660 SMR:O61660 STRING:6239.Y56A3A.27.2 PaxDb:O61660 EnsemblMetazoa:Y56A3A.27.1 EnsemblMetazoa:Y56A3A.27.2 GeneID:176631 KEGG:cel:CELE_Y56A3A.27 UCSC:Y56A3A.27.1 CTD:176631 WormBase:Y56A3A.27 InParanoid:O61660 OMA:NFKPETF NextBio:893376 PRO:PR:O61660 Uniprot:O61660) HSP 1 Score: 479.945 bits (1234), Expect = 6.178e-156 Identity = 254/514 (49.42%), Postives = 319/514 (62.06%), Query Frame = 0
Query: 33 KTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPSL-----AEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG--------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQ-DNRFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNES 502
+TL +A + L++WTD DREGE IG EI +VC RL + RA+FSEIT+ +I A R L DEK AVD R +LDLRIG+AFTR QTL L +F L Q+ISYGSCQFPT+GFV +RYK IE FV E FWK+ V H E+ KVEF W R RLFD+ + HD C E A VE KPKSKWRP LDTVELEKL KL +SAK TMQ AEKLY+ GFISYPRTETN +P LNL+ LV+ QTQS WG G++ K+YE +VRHFLA VS+DA G+ET V + + EKF G I + YLKVY YE+W ++ + Y E F + + G T P+ LTEADLISLMDK+GIGTDATHAEHIE IK R Y+G++ D + +P LG+AL DGYD MGF MSKP LR++LE LK IC+G + + VL EQI Y+ +F + + + + ++ +YL+++
Sbjct: 99 QTLREQAQRHDILVVWTDCDREGEAIGAEIVKVCRDSNRRLDIFRARFSEITKAAITRAARNLIRLDEKTVAAVDCRSELDLRIGSAFTRLQTLHLRNRFRDLLGQNDTSQVISYGSCQFPTLGFVTDRYKMIENFVSEPFWKLI-VEHTRESHKVEFLWDRNRLFDRDTVDILHDECKETKEAHVEKVAKKPKSKWRPQALDTVELEKLGISKLRMSAKQTMQVAEKLYSKGFISYPRTETNKFPAGLNLTPLVQQQTQSNIWGDFANEVLQNGVNPRNGRKSDEAHPPIHPLKFTEKHQLQGDDWKVYELVVRHFLACVSQDAQGEETMVNLTVGTEKFHASGLRIRDMGYLKVYVYEKWGNRLLPTYTEGERFTDFELKIGDGKTQAPDFLTEADLISLMDKYGIGTDATHAEHIEKIKTREYIGVRPDGKLIPSFLGLALVDGYDDMGFAMSKPDLRANLEIGLKEICDGRRQKQEVLDEQIGKYRAIFVESERKIGVLSQSLQRYLDKN 611 HSP 2 Score: 57.3806 bits (137), Expect = 4.438e-7 Identity = 24/43 (55.81%), Postives = 30/43 (69.77%), Query Frame = 0
Query: 671 CNCGN--LAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKW 711
C C A+ K V KEGPNKG++F+ CS P+ S+EKC FFKW
Sbjct: 716 CQCPEPMRAVTKVVQKEGPNKGKKFYTCSLPYTSSEKCNFFKW 758 HSP 3 Score: 53.5286 bits (127), Expect = 6.399e-6 Identity = 21/43 (48.84%), Postives = 30/43 (69.77%), Query Frame = 0
Query: 530 CKCD--LFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQW 570
C+C + A K V KEGPNKG+KFY C+ P + + +C+FF+W
Sbjct: 716 CQCPEPMRAVTKVVQKEGPNKGKKFYTCSLPYTSSEKCNFFKW 758 HSP 4 Score: 48.9062 bits (115), Expect = 1.747e-4 Identity = 21/46 (45.65%), Postives = 28/46 (60.87%), Query Frame = 0
Query: 596 ITCNCGK--VAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWA 639
+ C C + A + VQKEG NKG+ FY+C + +CNFFKWA
Sbjct: 714 VFCQCPEPMRAVTKVVQKEGPNKGKKFYTCSLPYTSSEKCNFFKWA 759
BLAST of EMLSAG00000003780 vs. C. finmarchicus
Match: gi|592918291|gb|GAXK01040084.1| (TSA: Calanus finmarchicus comp147672_c2_seq1 transcribed RNA sequence) HSP 1 Score: 474.552 bits (1220), Expect = 5.066e-160 Identity = 234/351 (66.67%), Postives = 271/351 (77.21%), Query Frame = 0
Query: 109 RQQLDLRIGAAFTRFQTLRLAKKFPS-LAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG--------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQD 420
R +LDLRIGAAFTRFQT+RL K FP+ L+++LISYGSCQFPTMGFVVERYKAIE F E FWK+K VTHE + KV+F+WKRVRLF Q A +VY DIC EN +A+VE+CKSKPK+KWRPLPLDTVELEKLASRKL +SAK TM AEKLYT G ISYPRTETNI+PKE+NL++LVE QT QWG G+E K+YEFIVRHFLA VS+DA+GKETTV IDI GEKF+GHG T+L+RNYL+VY Y+RWSDKEI++YE I EFEPTSID+V GST P LLTEADLI+LMDKHGIGTDATHAEHIET+K+R YV ++D
Sbjct: 1 RMELDLRIGAAFTRFQTMRLQKMFPNNLSDKLISYGSCQFPTMGFVVERYKAIENFTSEPFWKLK-VTHEVDGCKVDFTWKRVRLFHQMAVEVYKDICMENTMARVEECKSKPKNKWRPLPLDTVELEKLASRKLRLSAKTTMTIAEKLYTQGLISYPRTETNIFPKEMNLTSLVEAQTGDNQWGAFAGRILGEWNGPHPRAGKKSDQAHPPIHPIKHTSGLQGDEAKVYEFIVRHFLACVSQDAVGKETTVNIDIAGEKFVGHGLTVLQRNYLEVYVYDRWSDKEIIDYEQIREFEPTSIDIVDGSTEAPKLLTEADLIALMDKHGIGTDATHAEHIETVKSREYVFIED 1050
BLAST of EMLSAG00000003780 vs. C. finmarchicus
Match: gi|592918290|gb|GAXK01040085.1| (TSA: Calanus finmarchicus comp147672_c2_seq2 transcribed RNA sequence) HSP 1 Score: 401.364 bits (1030), Expect = 2.736e-132 Identity = 200/307 (65.15%), Postives = 232/307 (75.57%), Query Frame = 0
Query: 109 RQQLDLRIGAAFTRFQTLRLAKKFPS-LAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG--------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGS 376
R +LDLRIGAAFTRFQT+RL K FP+ L+++LISYGSCQFPTMGFVVERYKAIE F E FWK+K VTHE + KV+F+WKRVRLF Q A +VY DIC EN +A+VE+CKSKPK+KWRPLPLDTVELEKLASRKL +SAK TM AEKLYT G ISYPRTETNI+PKE+NL++LVE QT QWG G+E K+YEFIVRHFLA VS+DA+GKETTV IDI GEKF+GHG T+L+RNYL+VY Y+RWSDKEI++YE I EFEPTSID+V GS
Sbjct: 1 RMELDLRIGAAFTRFQTMRLQKMFPNNLSDKLISYGSCQFPTMGFVVERYKAIENFTSEPFWKLK-VTHEVDGCKVDFTWKRVRLFHQMAVEVYKDICMENTMARVEECKSKPKNKWRPLPLDTVELEKLASRKLRLSAKTTMTIAEKLYTQGLISYPRTETNIFPKEMNLTSLVEAQTGDNQWGAFAGRILGEWNGPHPRAGKKSDQAHPPIHPIKHTSGLQGDEAKVYEFIVRHFLACVSQDAVGKETTVNIDIAGEKFVGHGLTVLQRNYLEVYVYDRWSDKEIIDYEQIREFEPTSIDIVDGS 918
BLAST of EMLSAG00000003780 vs. C. finmarchicus
Match: gi|592918289|gb|GAXK01040086.1| (TSA: Calanus finmarchicus comp147672_c2_seq3 transcribed RNA sequence) HSP 1 Score: 385.185 bits (988), Expect = 3.584e-126 Identity = 190/294 (64.63%), Postives = 221/294 (75.17%), Query Frame = 0
Query: 165 PEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG--------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQD 420
PE FWK+K VTHE + KV+F+WKRVRLF Q A +VY DIC EN +A+VE+CKSKPK+KWRPLPLDTVELEKLASRKL +SAK TM AEKLYT G ISYPRTETNI+PKE+NL++LVE QT QWG G+E K+YEFIVRHFLA VS+DA+GKETTV IDI GEKF+GHG T+L+RNYL+VY Y+RWSDKEI++YE I EFEPTSID+V GST P LLTEADLI+LMDKHGIGTDATHAEHIET+K+R YV ++D
Sbjct: 2 PEPFWKLK-VTHEVDGCKVDFTWKRVRLFHQMAVEVYKDICMENTMARVEECKSKPKNKWRPLPLDTVELEKLASRKLRLSAKTTMTIAEKLYTQGLISYPRTETNIFPKEMNLTSLVEAQTGDNQWGAFAGRILGEWNGPHPRAGKKSDQAHPPIHPIKHTSGLQGDEAKVYEFIVRHFLACVSQDAVGKETTVNIDIAGEKFVGHGLTVLQRNYLEVYVYDRWSDKEIIDYEQIREFEPTSIDIVDGSTEAPKLLTEADLIALMDKHGIGTDATHAEHIETVKSREYVFIED 880
BLAST of EMLSAG00000003780 vs. C. finmarchicus
Match: gi|592918287|gb|GAXK01040088.1| (TSA: Calanus finmarchicus comp147672_c2_seq5 transcribed RNA sequence) HSP 1 Score: 312.383 bits (799), Expect = 6.291e-99 Identity = 156/250 (62.40%), Postives = 182/250 (72.80%), Query Frame = 0
Query: 165 PEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG--------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGS 376
PE FWK+K VTHE + KV+F+WKRVRLF Q A +VY DIC EN +A+VE+CKSKPK+KWRPLPLDTVELEKLASRKL +SAK TM AEKLYT G ISYPRTETNI+PKE+NL++LVE QT QWG G+E K+YEFIVRHFLA VS+DA+GKETTV IDI GEKF+GHG T+L+RNYL+VY Y+RWSDKEI++YE I EFEPTSID+V GS
Sbjct: 2 PEPFWKLK-VTHEVDGCKVDFTWKRVRLFHQMAVEVYKDICMENTMARVEECKSKPKNKWRPLPLDTVELEKLASRKLRLSAKTTMTIAEKLYTQGLISYPRTETNIFPKEMNLTSLVEAQTGDNQWGAFAGRILGEWNGPHPRAGKKSDQAHPPIHPIKHTSGLQGDEAKVYEFIVRHFLACVSQDAVGKETTVNIDIAGEKFVGHGLTVLQRNYLEVYVYDRWSDKEIIDYEQIREFEPTSIDIVDGS 748
BLAST of EMLSAG00000003780 vs. C. finmarchicus
Match: gi|592918286|gb|GAXK01040089.1| (TSA: Calanus finmarchicus comp147672_c2_seq6 transcribed RNA sequence) HSP 1 Score: 310.071 bits (793), Expect = 4.332e-98 Identity = 158/250 (63.20%), Postives = 182/250 (72.80%), Query Frame = 0
Query: 109 RQQLDLRIGAAFTRFQTLRLAKKFPS-LAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG--------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKET 319
R +LDLRIGAAFTRFQT+RL K FP+ L+++LISYGSCQFPTMGFVVERYKAIE F E FWK+K VTHE + KV+F+WKRVRLF Q A +VY DIC EN +A+VE+CKSKPK+KWRPLPLDTVELEKLASRKL +SAK TM AEKLYT G ISYPRTETNI+PKE+NL++LVE QT QWG G+E K+YEFIVRHFLA VS+DA+GKET
Sbjct: 1 RMELDLRIGAAFTRFQTMRLQKMFPNNLSDKLISYGSCQFPTMGFVVERYKAIENFTSEPFWKLK-VTHEVDGCKVDFTWKRVRLFHQMAVEVYKDICMENTMARVEECKSKPKNKWRPLPLDTVELEKLASRKLRLSAKTTMTIAEKLYTQGLISYPRTETNIFPKEMNLTSLVEAQTGDNQWGAFAGRILGEWNGPHPRAGKKSDQAHPPIHPIKHTSGLQGDEAKVYEFIVRHFLACVSQDAVGKET 747
BLAST of EMLSAG00000003780 vs. C. finmarchicus
Match: gi|592902826|gb|GAXK01055549.1| (TSA: Calanus finmarchicus comp85885_c6_seq2 transcribed RNA sequence) HSP 1 Score: 316.235 bits (809), Expect = 1.744e-94 Identity = 208/607 (34.27%), Postives = 288/607 (47.45%), Query Frame = 0
Query: 35 LEREASNCEWLIIWTDGDREGENIGFEIREVC---LRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPSLAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG--------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKE-ILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQDNR-FVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKID---EACIKYLNESPRDSNDEG-------FFSMSNESRFTPT---------------LSQTIKCKCDLFAAEKTVVKEGPNKGRKFYCC-----NAP---MSGANRC 565
L EA C+++++W D D+EGENI FE+ + +R R V RAKFS IT I A+ L EPDE QS++VD RQ+LDLRIG AFTRFQT K+ L LISYG CQ PT+GF V+R+ I+ PE +W ++ + ++ W+R+R FD+ ++ AKV +K K K +PL L+TVEL ++AS L + + M AEKLY G+ISYPRTE+ Y +L ++V Q + WG G KLY+FIVRHFL +VS + +T + EKFI G + E + V ++ +E I + + LV TSPP LTE+DLI+LM+KHG+GTDA+ HI I RNY ++ R VP LGI L GY + ++ KP +R ++E L I +G E VL + +K F V+ + +D E L +S R + G + F PT L Q +KC D F + V KG+ F C N P MSG + C
Sbjct: 61 LAAEAKGCDYIVLWLDCDKEGENICFEVLDAVRSSMRRQDRNTVFRAKFSSITDKDIVAAMNHLGEPDENQSRSVDARQELDLRIGCAFTRFQTRFFQGKYGDLDSSLISYGPCQTPTLGFCVDRHDTIQTHKPEPYWVLQVSVDTKDEKRLNLEWERIRCFDREVAVMFLQTVKGQTEAKVISVTTKEKQKEKPLALNTVELMRVASSGLGMGPQHAMSIAEKLYLQGYISYPRTESTQYADSFDLKDVVRQQQHNSDWGDICKELLAGGLAKQRKGHDAGDHPPITPCRAVGRGELDGETWKLYDFIVRHFLGTVSSNCKYDQTVATMMCGEEKFILTGKKVTEPGFTGVMTWQAIPAEESIPQLNQGDRLAVKDVRLVDRQTSPPGYLTESDLITLMEKHGVGTDASIPVHINNICTRNYCTVEAGRKLVPTSLGIVLVHGYLKIDPDLVKPTMRGAVEKQLDLIAQGKANFESVLSHTLEVFKLKFLYFVKGITGMDQLFEVSFSSLADSGRPFSRCGKCRRFMKLVEAKPKRLFCPTCDETYNVPQQNGALKLHQELKCPLDDF---ELVYFSAGAKGKSFVFCPFCFSNPPFPGMSGGSNC 1872
BLAST of EMLSAG00000003780 vs. C. finmarchicus
Match: gi|592902827|gb|GAXK01055548.1| (TSA: Calanus finmarchicus comp85885_c6_seq1 transcribed RNA sequence) HSP 1 Score: 315.849 bits (808), Expect = 4.113e-94 Identity = 208/607 (34.27%), Postives = 288/607 (47.45%), Query Frame = 0
Query: 35 LEREASNCEWLIIWTDGDREGENIGFEIREVC---LRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPSLAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG--------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKE-ILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQDNR-FVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKID---EACIKYLNESPRDSNDEG-------FFSMSNESRFTPT---------------LSQTIKCKCDLFAAEKTVVKEGPNKGRKFYCC-----NAP---MSGANRC 565
L EA C+++++W D D+EGENI FE+ + +R R V RAKFS IT I A+ L EPDE QS++VD RQ+LDLRIG AFTRFQT K+ L LISYG CQ PT+GF V+R+ I+ PE +W ++ + ++ W+R+R FD+ ++ AKV +K K K +PL L+TVEL ++AS L + + M AEKLY G+ISYPRTE+ Y +L ++V Q + WG G KLY+FIVRHFL +VS + +T + EKFI G + E + V ++ +E I + + LV TSPP LTE+DLI+LM+KHG+GTDA+ HI I RNY ++ R VP LGI L GY + ++ KP +R ++E L I +G E VL + +K F V+ + +D E L +S R + G + F PT L Q +KC D F + V KG+ F C N P MSG + C
Sbjct: 157 LAAEAKGCDYIVLWLDCDKEGENICFEVLDAVRSSMRRQDRNTVFRAKFSSITDKDIVAAMNHLGEPDENQSRSVDARQELDLRIGCAFTRFQTRFFQGKYGDLDSSLISYGPCQTPTLGFCVDRHDTIQTHKPEPYWVLQVSVDTKDEKRLNLEWERIRCFDREVAVMFLQTVKGQTEAKVISVTTKEKQKEKPLALNTVELMRVASSGLGMGPQHAMSIAEKLYLQGYISYPRTESTQYADSFDLKDVVRQQQHNSDWGDICKELLAGGLAKQRKGHDAGDHPPITPCRAVGRGELDGETWKLYDFIVRHFLGTVSSNCKYDQTVATMMCGEEKFILTGKKVTEPGFTGVMTWQAIPAEESIPQLNQGDRLAVKDVRLVDRQTSPPGYLTESDLITLMEKHGVGTDASIPVHINNICTRNYCTVEAGRKLVPTSLGIVLVHGYLKIDPDLVKPTMRGAVEKQLDLIAQGKANFESVLSHTLEVFKLKFLYFVKGITGMDQLFEVSFSSLADSGRPFSRCGKCRRFMKLVEAKPKRLFCPTCDETYNVPQQNGALKLHQELKCPLDDF---ELVYFSAGAKGKSFVFCPFCFSNPPFPGMSGGSNC 1968
BLAST of EMLSAG00000003780 vs. C. finmarchicus
Match: gi|592902825|gb|GAXK01055550.1| (TSA: Calanus finmarchicus comp85885_c6_seq3 transcribed RNA sequence) HSP 1 Score: 313.538 bits (802), Expect = 6.385e-94 Identity = 182/502 (36.25%), Postives = 258/502 (51.39%), Query Frame = 0
Query: 35 LEREASNCEWLIIWTDGDREGENIGFEIREVC---LRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPSLAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG--------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERW-SDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQDNR-FVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDE 493
L EA C+++++W D D+EGENI FE+ + +R R V RAKFS IT I A+ L EPDE QS++VD RQ+LDLRIG AFTRFQT K+ L LISYG CQ PT+GF V+R+ I+ PE +W ++ + ++ W+R+R FD+ ++ AKV +K K K +PL L+TVEL ++AS L + + M AEKLY G+ISYPRTE+ Y +L ++V Q + WG G KLY+FIVRHFL +VS + +T + EKFI G + E + V ++ +++ I + + LV TSPP LTE+DLI+LM+KHG+GTDA+ HI I RNY ++ R VP LGI L GY + ++ KP +R ++E L I +G E VL + +K F V+ + +D+
Sbjct: 240 LAAEAKGCDYIVLWLDCDKEGENICFEVLDAVRSSMRRQDRNTVFRAKFSSITDKDIVAAMNHLGEPDENQSRSVDARQELDLRIGCAFTRFQTRFFQGKYGDLDSSLISYGPCQTPTLGFCVDRHDTIQTHKPEPYWVLQVSVDTKDEKRLNLEWERIRCFDREVAVMFLQTVKGQTEAKVISVTTKEKQKEKPLALNTVELMRVASSGLGMGPQHAMSIAEKLYLQGYISYPRTESTQYADSFDLKDVVRQQQHNSDWGDICKELLAGGLAKQRKGHDAGDHPPITPCRAVGRGELDGETWKLYDFIVRHFLGTVSSNCKYDQTVATMMCGEEKFILTGKKVTEPGFTGVMTWQAIPAEESIPQLNQGDRLAVKDVRLVDRQTSPPGYLTESDLITLMEKHGVGTDASIPVHINNICTRNYCTVEAGRKLVPTSLGIVLVHGYLKIDPDLVKPTMRGAVEKQLDLIAQGKANFESVLSHTLEVFKLKFLYFVKGITGMDQ 1745
BLAST of EMLSAG00000003780 vs. C. finmarchicus
Match: gi|592918285|gb|GAXK01040090.1| (TSA: Calanus finmarchicus comp147672_c2_seq7 transcribed RNA sequence) HSP 1 Score: 286.189 bits (731), Expect = 3.000e-89 Identity = 143/227 (63.00%), Postives = 165/227 (72.69%), Query Frame = 0
Query: 232 VELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG--------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQD 420
VELEKLASRKL +SAK TM AEKLYT G ISYPRTETNI+PKE+NL++LVE QT QWG G+E K+YEFIVRHFLA VS+DA+GKETTV IDI GEKF+GHG T+L+RNYL+VY Y+RWSDKEI++YE I EFEPTSID+V GST P LLTEADLI+LMDKHGIGTDATHAEHIET+K+R YV ++D
Sbjct: 2 VELEKLASRKLRLSAKTTMTIAEKLYTQGLISYPRTETNIFPKEMNLTSLVEAQTGDNQWGAFAGRILGEWNGPHPRAGKKSDQAHPPIHPIKHTSGLQGDEAKVYEFIVRHFLACVSQDAVGKETTVNIDIAGEKFVGHGLTVLQRNYLEVYVYDRWSDKEIIDYEQIREFEPTSIDIVDGSTEAPKLLTEADLIALMDKHGIGTDATHAEHIETVKSREYVFIED 682
BLAST of EMLSAG00000003780 vs. C. finmarchicus
Match: gi|592918279|gb|GAXK01040096.1| (TSA: Calanus finmarchicus comp147672_c3_seq1 transcribed RNA sequence) HSP 1 Score: 288.5 bits (737), Expect = 6.575e-89 Identity = 140/203 (68.97%), Postives = 165/203 (81.28%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFP-SLAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVE 233
+K+LE+E C+ LIIWTD DREGENIG E+ VC + +KVLRAKFSEITRPSIE A+R L + +E S AVD R +LDLRIGAAFTRFQT+RL K FP +L+++LISYGSCQFPTMGFVVERYKAIE F PE FWK+K VTHE + KV+F+WKRVRLF Q A +VY DIC EN +A+VE+CKSKPK+KWRPLPLDTVE
Sbjct: 2 KKSLEKEVRGCKLLIIWTDCDREGENIGMEVVTVCRAINRGIKVLRAKFSEITRPSIERAMRTLGQINENVSAAVDCRMELDLRIGAAFTRFQTMRLQKMFPNNLSDKLISYGSCQFPTMGFVVERYKAIENFTPEPFWKLK-VTHEVDGCKVDFTWKRVRLFHQMAVEVYKDICMENTMARVEECKSKPKNKWRPLPLDTVE 607 HSP 2 Score: 41.5874 bits (96), Expect = 8.171e-3 Identity = 19/27 (70.37%), Postives = 24/27 (88.89%), Query Frame = 0
Query: 7 KVLNVAEKNXAAKNIADVLSRGSANRK 33
KVLNVAEKN AAKNIA+++S G +NR+
Sbjct: 815 KVLNVAEKNDAAKNIAEIMSGGHSNRR 895
BLAST of EMLSAG00000003780 vs. L. salmonis peptides
Match: EMLSAP00000003780 (pep:novel supercontig:LSalAtl2s:LSalAtl2s204:481614:491509:1 gene:EMLSAG00000003780 transcript:EMLSAT00000003780 description:"maker-LSalAtl2s204-snap-gene-5.13") HSP 1 Score: 1618.21 bits (4189), Expect = 0.000e+0 Identity = 786/786 (100.00%), Postives = 786/786 (100.00%), Query Frame = 0
Query: 1 MSSSVVKVLNVAEKNXAAKNIADVLSRGSANRKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPSLAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWGGNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQDNRFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRDSNDEGFFSMSNESRFTPTLSQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSSAXIPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPSTSSFNSNSQPAINDENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGNFNGNDSNFRRPSRDSTVPSRGGGGGLKRSGSTTREGGSDKKKRRCGLCHREGHTRNKCPNNR 786
MSSSVVKVLNVAEKNXAAKNIADVLSRGSANRKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPSLAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWGGNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQDNRFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRDSNDEGFFSMSNESRFTPTLSQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSSAXIPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPSTSSFNSNSQPAINDENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGNFNGNDSNFRRPSRDSTVPSRGGGGGLKRSGSTTREGGSDKKKRRCGLCHREGHTRNKCPNNR
Sbjct: 1 MSSSVVKVLNVAEKNXAAKNIADVLSRGSANRKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPSLAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWGGNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQDNRFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRDSNDEGFFSMSNESRFTPTLSQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSSAXIPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPSTSSFNSNSQPAINDENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGNFNGNDSNFRRPSRDSTVPSRGGGGGLKRSGSTTREGGSDKKKRRCGLCHREGHTRNKCPNNR 786
BLAST of EMLSAG00000003780 vs. L. salmonis peptides
Match: EMLSAP00000005531 (pep:novel supercontig:LSalAtl2s:LSalAtl2s297:32962:36363:1 gene:EMLSAG00000005531 transcript:EMLSAT00000005531 description:"maker-LSalAtl2s297-snap-gene-0.26") HSP 1 Score: 114.39 bits (285), Expect = 5.819e-27 Identity = 72/242 (29.75%), Postives = 124/242 (51.24%), Query Frame = 0
Query: 278 LSNLVEMQTQSPQWGGNEG---------------------KLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKV-----YPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQDN-RFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKID 492
+ NL+EM +P+ G + G ++Y++IVRHFL +VS + + T V + I EKF +++R Y ++ +P E + +V++ ++ I + + T PP LTE+DLI+LM+KHGIGTDA+ HI+ + R YV ++ R VP LGI L GY + ++ +RS++E L+ I +G + VL+ + +K F + +++ +D
Sbjct: 8 VKNLLEMGPNNPRKGHDAGDHPPITPTHTVSREQLDVDQWRIYDYIVRHFLGTVSYNLKMQNTNVHLKIGEEKFSFTKTKLIDRGYTEIMHWKYFPSEEEGSTNLKKDDVLDIYD---IKIDSRQTDPPGYLTESDLITLMEKHGIGTDASIPVHIKNVVLRGYVTVESGRRLVPKTLGIVLVHGYQKIDPDLVHYKMRSAVERQLELIAKGKEDYLSVLKHTLEVFKAKFAYFISNIEGMD 246
BLAST of EMLSAG00000003780 vs. SwissProt
Match: gi|6686029|sp|O70157.1|TOP3A_MOUSE (RecName: Full=DNA topoisomerase 3-alpha; AltName: Full=DNA topoisomerase III alpha) HSP 1 Score: 647.506 bits (1669), Expect = 0.000e+0 Identity = 369/767 (48.11%), Postives = 455/767 (59.32%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPS-LAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG-------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGL-QDNRFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRDSNDEGFF-SMSNESRFTPTLSQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSSAXIPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRF-------FYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPSTSSFNSN-------SQPAIN--------------------DENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGN 724
+KTLERE +C+ L+IWTD DREGENIGFEI VC V P L+VLRA+FSEIT ++ A LTEPD++ S AVDVRQ+LDLRIGAAFTRFQTLRL + FP LAEQLISYGSCQFPT+GFVVER+KAI+AFVPE F KIK VTH++++ VEF+WKR RLF+ A V + +C E+P+A V + +SKPKSKWRP LDTVELEKLASRKL I+AK TM+ AEKLYT G+ISYPRTETNI+PK+LNL LVE QT P WG G++ +LYEFIVRHFLA S+DA G+ETTV IDI E+F+ HG IL RNYL VYPY+ WSDK + YE F+P+++++V G TSPP LLTEADLI+LM+KHGIGTDATHAEHIETIK R YVGL D RF+PG LG+ L +GYD+MG+EMSKP LR+ LEADLK ICEG K VL++Q+ YK VF AV +K+DEA +YL E + E + +M R P +C D+ V+K + G C P C W + L +S N C V + K GS C + E F + S + + ++ + N SQP +N + NS+TCNCG A+ TV K+GPN+GR F+ C SN C FF W D +SHS G
Sbjct: 130 KKTLERETHHCQALVIWTDCDREGENIGFEIIHVCKAVKPNLRVLRARFSEITPHAVRTACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFPEVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPEVFHKIK-VTHDHKDGTVEFNWKRYRLFNHTACLVLYQLCMEDPMATVVEVRSKPKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYISYPRTETNIFPKDLNLVALVEQQTVDPHWGAFAQTILERGGPTPRNGSKSDQAHPPIHPTKYTSGLQGDDRRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLIILARNYLDVYPYDHWSDKLLPVYEQGSHFQPSTVEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVGLTSDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICEGKKDKFQVLRQQVQKYKQVFIEAVAKAKKLDEALSQYLGERTEMAQQEEIYPAMPEPVRKCP------QCNKDM------VLKTKKSGGFYLSCMGFP-----ECRSAVWFPDSVL----------EASRDNSVCSVCQPPPVYRLKLKFKRGSLPPAMPLEFVGCIGGCDETLKEIFGLRFPRALPRASQPSGHLQASQALNRMDSSQHNLSQPLVNRHTRPSKTVAQALLPPTTAGESNSVTCNCGREAVLLTVRKQGPNQGRHFYKC-----SNGDCNFFLWAD---SSHSTGGG 860 HSP 2 Score: 133.265 bits (334), Expect = 1.023e-30 Identity = 81/233 (34.76%), Postives = 113/233 (48.50%), Query Frame = 0
Query: 575 PLPSSSSAXIPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPSTSSFNSNSQPAI----------------NDENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGNFN-----GNDSNFRRPSRDSTVPSRGGGGGLKRSGSTTREGGSDKKKRRCGLCHREGHTRNKCPNNR 786
P + + A +P ++ +S+TCNCG+ A TV+K+G N+GR FY C CNFF WA S TP+++S S + + C CG A+ +TV K+GPNKGR+F C+KP ++C FF+W DE + PG+F G +RP S P R+GS+ G + KK R+C LCH+ GHTR CP NR
Sbjct: 793 PSKTVAQALLPPTTA-GESNSVTCNCGREAVLLTVRKQGPNQGRHFYKC-----SNGDCNFFLWADSSHSTGGGTPTSASGPPGSSVGCPSSVGSHMDGFGSLGSDSDGGTPCLCGQPAVTRTVQKDGPNKGRQFHTCAKP--REQQCGFFQWVDE----NVAPGSFAAPAWPGGRGKAQRPEAASKRP---------RAGSSD-AGSTVKKPRKCSLCHQPGHTRTFCPQNR 1003 HSP 3 Score: 75.8702 bits (185), Expect = 8.666e-13 Identity = 49/138 (35.51%), Postives = 64/138 (46.38%), Query Frame = 0
Query: 525 SQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDE--------------PP-----LPSSSSAXIPSNSSLSNXS--SITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXE 641
S ++ C C A TV K+GPN+GR FY C+ C+FF W D PP PSS + + SL + S C CG+ A RTVQK+G NKGR F++C +C FF+W E
Sbjct: 810 SNSVTCNCGREAVLLTVRKQGPNQGRHFYKCS-----NGDCNFFLWADSSHSTGGGTPTSASGPPGSSVGCPSSVGSHMDGFGSLGSDSDGGTPCLCGQPAVTRTVQKDGPNKGRQFHTC--AKPREQQCGFFQWVDE 940
BLAST of EMLSAG00000003780 vs. SwissProt
Match: gi|2501242|sp|Q13472.1|TOP3A_HUMAN (RecName: Full=DNA topoisomerase 3-alpha; AltName: Full=DNA topoisomerase III alpha) HSP 1 Score: 639.032 bits (1647), Expect = 0.000e+0 Identity = 366/767 (47.72%), Postives = 455/767 (59.32%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPS-LAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG-------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQ-DNRFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRDSNDEGFFSMSNESRFTPTLSQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSSAXIPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPV-----------NMAEGSRCNFFKWAXEVSSFNNNTPSTSSFN-----SNSQPA--------------------INDENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPG 723
+KTLERE C+ L+IWTD DREGENIGFEI VC V P L+VLRA+FSEIT ++ A LTEPD++ S AVDVRQ+LDLRIGAAFTRFQTLRL + FP LAEQLISYGSCQFPT+GFVVER+KAI+AFVPE F +IK VTH++++ VEF+WKR RLF+ A V + +C E+P+A V + +SKPKSKWRP LDTVELEKLASRKL I+AK TM+ AEKLYT G+ISYPRTETNI+P++LNL+ LVE QT P+WG G+E +LYEFIVRHFLA S+DA G+ETTV IDI E+F+ HG IL RNYL VYPY+ WSDK + YE F+P+++++V G TSPP LLTEADLI+LM+KHGIGTDATHAEHIETIK R YVGL D RF+PG LG+ L +GYD+MG+EMSKP LR+ LEADLK IC+G K VVL++Q+ YK VF AV +K+DEA +Y + E + E + + +C D+ V+K N G C P C W+ + L +S SS+ C YR K +G + P+ + E F S + + S N + QPA + NS+TCNCG A+ TV KEGPN+GR+F+ C+ GS C FF W D NPG
Sbjct: 130 KKTLERETRQCQALVIWTDCDREGENIGFEIIHVCKAVKPNLQVLRARFSEITPHAVRTACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFPEVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPEIFHRIK-VTHDHKDGIVEFNWKRHRLFNHTACLVLYQLCVEDPMATVVEVRSKPKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYISYPRTETNIFPRDLNLTVLVEQQTPDPRWGAFAQSILERGGPTPRNGNKSDQAHPPIHPTKYTNNLQGDEQRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLMILARNYLDVYPYDHWSDKILPVYEQGSHFQPSTVEMVDGETSPPKLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVGLTPDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICDGKKDKFVVLRQQVQKYKQVFIEAVAKAKKLDEALAQYFGNGTELAQQEDIYPAMPEP-----IRKCPQCNKDM------VLKTKKNGGFYLSCMGFP-----ECRSAVWLPDSVLEASRD------------SSVCPVCQPHPVYRL--KLKFKRGSLPPTMPLEFVCCIGGCDDTLREILDLRFSGGPPRASQPSGRLQANQSLNRMDNSQHPQPADSRQTGSSKALAQTLPPPTAAGESNSVTCNCGQEAVLLTVRKEGPNRGRQFFKCNG--GS---CNFFLWADS-----PNPG 855 HSP 2 Score: 120.168 bits (300), Expect = 1.302e-26 Identity = 72/220 (32.73%), Postives = 104/220 (47.27%), Query Frame = 0
Query: 584 IPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPST------SSFNSNSQPAIN----------DENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTN-SHSNPGNFNGNDSNFRRPSRDSTVPSRGGGGGLKRSGSTTREGGSDKKKRRCGLCHREGHTRNKCPNNR 786
+P ++ +S+TCNCG+ A TV+KEG N+GR F+ C G CNFF WA + P+ +S P I+ + +C C ++ +TV K+GPNKGR+F C+KP ++C FF+W DE T S ++ G+ S P S++ G + KK R+C LCH+ GHTR CP NR
Sbjct: 799 LPPPTAAGESNSVTCNCGQEAVLLTVRKEGPNRGRQFFKC-----NGGSCNFFLWADSPNPGAGGPPALAYRPLGASLGCPPGPGIHLGGFGNPGDGSGSGTSCLCSQPSVTRTVQKDGPNKGRQFHTCAKP--REQQCGFFQWVDENTAPGTSGAPSWTGDRGRTLESEARSKRP----------RASSSDMGSTAKKPRKCSLCHQPGHTRPFCPQNR 1001 HSP 3 Score: 78.1814 bits (191), Expect = 1.690e-13 Identity = 57/175 (32.57%), Postives = 75/175 (42.86%), Query Frame = 0
Query: 503 PRDSNDEGFFSMSNESRFTPTL---SQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDE-------PPL----PSSSSAXIP----------SNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPSTS 653
P DS G ++ PT S ++ C C A TV KEGPN+GR+F+ CN C+FF W D PP P +S P N + S +C C + + RTVQK+G NKGR F++C +C FF+W E N P TS
Sbjct: 783 PADSRQTGSSKALAQTLPPPTAAGESNSVTCNCGQEAVLLTVRKEGPNRGRQFFKCN-----GGSCNFFLWADSPNPGAGGPPALAYRPLGASLGCPPGPGIHLGGFGNPGDGSGSGTSCLCSQPSVTRTVQKDGPNKGRQFHTC--AKPREQQCGFFQWVDE-----NTAPGTS 945
BLAST of EMLSAG00000003780 vs. SwissProt
Match: gi|33860232|sp|Q9NG98.2|TOP3A_DROME (RecName: Full=DNA topoisomerase 3-alpha; AltName: Full=DNA topoisomerase III alpha) HSP 1 Score: 547.354 bits (1409), Expect = 5.189e-178 Identity = 279/512 (54.49%), Postives = 341/512 (66.60%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFP-SLAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTE--NPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQDNRF-VPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESP 503
++TLERE C+ LIIWTD DREGENIG+EI +VC + P + V RA FSEIT ++ AL+ L +PD++QS AVDVR +LDLR GAA TRFQT+RL + FP +A++LISYGSCQ PT+GFV ERYK IEAFV E FWKIK V H ++ VEF+W R RLFD+ A + Y +C +P A VE KPK KWRP PLDTVE+EKL SRKL +SAK TM AEKLYT GFISYPRTETN + KE L+ LVEMQT WG GNE ++YE +VRHFLA VSKDA+G ET V IDI GEKF +G I ERNYL VY Y++WS K+I +YE + FEPT + L G+T+ P LLTEADLI+LM+KHGIGTDATHAEHI TIK R Y+G+ D F VPG +G+ L +GYDAM ++KP LR+ E DLK IC+G K P+VVL EQI YK ++ + +D +NE+P
Sbjct: 122 KRTLEREVRGCQGLIIWTDCDREGENIGYEIIDVCRAIKPNISVYRATFSEITTVAVRRALQQLGQPDKRQSDAVDVRTELDLRTGAAITRFQTMRLQRLFPEKIADKLISYGSCQIPTLGFVAERYKEIEAFVSEPFWKIK-VLHTIDDLTVEFNWARNRLFDKEACENYLLLCLAEPDPRALVESVTVKPKHKWRPTPLDTVEMEKLGSRKLKLSAKETMTIAEKLYTKGFISYPRTETNQFSKEFALAPLVEMQTGHRDWGAFAQRVIEWGPNPRNGNKSDQAHPPIHPTKLAENLQGNEARVYELVVRHFLACVSKDAVGSETLVHIDIAGEKFTANGLVIHERNYLDVYVYDKWSAKQIHHYENGQRFEPTEVSLHEGATTAPPLLTEADLIALMEKHGIGTDATHAEHINTIKERGYIGVLDKGFLVPGVIGMGLYEGYDAMELALAKPQLRAEFELDLKLICQGQKDPKVVLTEQIAKYKQAYQQITDKITAMDAKISARINETP 632 HSP 2 Score: 106.686 bits (265), Expect = 2.947e-22 Identity = 78/244 (31.97%), Postives = 106/244 (43.44%), Query Frame = 0
Query: 588 SSLSNXSSITCN-CGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSF---NNNT----PSTSSFNSN---SQPAINDENS-------------------------------------LTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGNFNGNDSNFRRPSRDSTVPSRGGGGGLKRSGSTTREGGSDKKKRRCGLCHREGHTRNKCP 783
SS+ ++ C C + A TV+K G N GR +Y CP + CNFF+WA E S N+T ST+S+ SN + P+I NS + CNCG LA + TV K+GPN+GR F+ C + C FFKW DE N ++ ++ + N S+ + + S G K RRCGLC +EGHTRNKCP
Sbjct: 1025 SSVPESETVLCTGCQQPARQNTVRKNGPNLGRLYYKCP----KPDECNFFQWADEPPSSAKSKNSTGSAPQSTTSWGSNRVVTLPSIQQSNSQRGQSSMRSNSSSTVTITQTKTKQQERNTATPGDGEEVMCNCGQLASQLTVRKDGPNQGRPFYACPT---REKSCGFFKWGDEDQNQGASSTSWGSANRNPPGRSQPTAITSDG------------------PKTRRCGLCRKEGHTRNKCP 1243
BLAST of EMLSAG00000003780 vs. SwissProt
Match: gi|6686028|sp|O61660.1|TOP3_CAEEL (RecName: Full=DNA topoisomerase 3; AltName: Full=DNA topoisomerase III) HSP 1 Score: 479.945 bits (1234), Expect = 1.050e-157 Identity = 254/514 (49.42%), Postives = 319/514 (62.06%), Query Frame = 0
Query: 33 KTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPSL-----AEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG--------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQ-DNRFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNES 502
+TL +A + L++WTD DREGE IG EI +VC RL + RA+FSEIT+ +I A R L DEK AVD R +LDLRIG+AFTR QTL L +F L Q+ISYGSCQFPT+GFV +RYK IE FV E FWK+ V H E+ KVEF W R RLFD+ + HD C E A VE KPKSKWRP LDTVELEKL KL +SAK TMQ AEKLY+ GFISYPRTETN +P LNL+ LV+ QTQS WG G++ K+YE +VRHFLA VS+DA G+ET V + + EKF G I + YLKVY YE+W ++ + Y E F + + G T P+ LTEADLISLMDK+GIGTDATHAEHIE IK R Y+G++ D + +P LG+AL DGYD MGF MSKP LR++LE LK IC+G + + VL EQI Y+ +F + + + + ++ +YL+++
Sbjct: 99 QTLREQAQRHDILVVWTDCDREGEAIGAEIVKVCRDSNRRLDIFRARFSEITKAAITRAARNLIRLDEKTVAAVDCRSELDLRIGSAFTRLQTLHLRNRFRDLLGQNDTSQVISYGSCQFPTLGFVTDRYKMIENFVSEPFWKLI-VEHTRESHKVEFLWDRNRLFDRDTVDILHDECKETKEAHVEKVAKKPKSKWRPQALDTVELEKLGISKLRMSAKQTMQVAEKLYSKGFISYPRTETNKFPAGLNLTPLVQQQTQSNIWGDFANEVLQNGVNPRNGRKSDEAHPPIHPLKFTEKHQLQGDDWKVYELVVRHFLACVSQDAQGEETMVNLTVGTEKFHASGLRIRDMGYLKVYVYEKWGNRLLPTYTEGERFTDFELKIGDGKTQAPDFLTEADLISLMDKYGIGTDATHAEHIEKIKTREYIGVRPDGKLIPSFLGLALVDGYDDMGFAMSKPDLRANLEIGLKEICDGRRQKQEVLDEQIGKYRAIFVESERKIGVLSQSLQRYLDKN 611 HSP 2 Score: 57.3806 bits (137), Expect = 3.481e-7 Identity = 24/43 (55.81%), Postives = 30/43 (69.77%), Query Frame = 0
Query: 671 CNCGN--LAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKW 711
C C A+ K V KEGPNKG++F+ CS P+ S+EKC FFKW
Sbjct: 716 CQCPEPMRAVTKVVQKEGPNKGKKFYTCSLPYTSSEKCNFFKW 758
BLAST of EMLSAG00000003780 vs. SwissProt
Match: gi|75180667|sp|Q9LVP1.1|TOP3A_ARATH (RecName: Full=DNA topoisomerase 3-alpha) HSP 1 Score: 421.394 bits (1082), Expect = 3.503e-133 Identity = 275/771 (35.67%), Postives = 397/771 (51.49%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFP--SLAEQ---LISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDC-KSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQW--------------------GGNEGK-----------------------LYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQDN-RFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRDSNDEGFFSMSNESRFTPTLSQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSSAXI-------PSNSSLSNXSSITC-------NCGKVAAYRTVQKE---------GSNKGRFFYSCPVNMAEGS---RCNFFKWAXEVSSFNNNTPSTSSFNSNSQPAI----NDENSLTCN-CGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSN 721
+KTLE EA +WL++W D DREGENI FE+ +VC V L + RA FS + I A++ L +P++ ++AVD RQ++DLRIGA+FTRFQT+ L +F S E+ +ISYG CQFPT+GF+VERY I+A PE FW I +H+ E F+W R LFD + + +++C E P A V + + + K+ P PL+T+ELEK ASR +S++ TM+ AE+LY +GFISYPRTET+ + +L +VE QT+ P W GG++ K +YE +VRH+LA VS+ A+ ETTV IDI GE+F G IL +NYL+VY +E W I YE ++F PT++ L A T PP LL EADL+S MDK GIGTDAT +HI+ + +R Y N RF P LG AL GYD MG+E+ KP+LR+ +E D+ + G K VL+ + K F A K+ EA + S ++ DE +ES+ T + ++ +C+L +++ + C N P +C W+ P L +S + + P L I + G V + K+ S R + P N +GS + N + + N PS + NS+P NDE++++CN CG+ + +T + E N+GR+F+ C + C FF W D + NS N
Sbjct: 105 KKTLEEEARKSDWLVLWLDCDREGENIAFEVVDVCRAVKHNLFIRRAHFSALIDRDIHEAVQNLRDPNQLFAEAVDARQEIDLRIGASFTRFQTMLLRDRFAIDSTGEERSRVISYGPCQFPTLGFIVERYWEIQAHEPEEFWTIN-CSHQSEEGLATFNWMRGHLFDYASAVILYEMCVEEPTATVMNVPHPRERFKYPPYPLNTIELEKRASRYFRLSSEHTMKVAEELYQAGFISYPRTETDSFSSRTDLRAMVEEQTRHPAWGSYAQRLLEPEGGLWRNPANGGHDDKAHPPIHPTKFSSGESNWSRDHLNVYELVVRHYLACVSQPAVAAETTVEIDIAGERFSASGRAILAKNYLEVYRFESWGGSVIPVYEKGQQFIPTTLTLDAAVTRPPPLLCEADLLSCMDKAGIGTDATMHDHIKKLLDRGYATKDANTRFSPTNLGEALVMGYDDMGYELWKPNLRALMEHDMNEVSVGRKTKAEVLETCLQQMKACFLDARVKKSKLLEAMTIFFERS--NNTDE------SESQ---TAGEVVR-RCNLCNESDMALRKNRDGNFMVGCMNYP-----QCRNAVWLPGPTLEASVTTNVCQSCGPGPVYKILFKFRQIGIPPGFDVNHLGCVGGCDDILKQLIDICGTGSRSQARRTPGTAPSNNIQGSNTRQSNVCIHCQQRGHASTNCPSRVPASRNSRPTATNPRNDESTVSCNTCGSQCVLRTANTEA-NRGRQFFSC-----PTQGCSFFAWEDSINNSSGN 851
BLAST of EMLSAG00000003780 vs. SwissProt
Match: gi|74818660|sp|Q8T2T7.1|TOP3_DICDI (RecName: Full=DNA topoisomerase 3; AltName: Full=DNA topoisomerase III) HSP 1 Score: 407.912 bits (1047), Expect = 4.183e-129 Identity = 229/538 (42.57%), Postives = 312/538 (57.99%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPSLA--------------------------EQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTK------VEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG--------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGL-QDNRFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKY 498
+KTLERE + LI+W D DREGENI FE+ EVC + + RA FS I I+ A + L +P+EK S AVD R ++DLRIGAAFTRFQTL L KKF ++ +++ISYG CQFPT+GFVVERY I F PE FW + V HE +T V FSW R RLFD A + ++ C +N A V D SK +S++RP+PL T+EL+K AS+KL IS+ TMQ AE+LYT G ISYPRTET+ + +L L+ Q +P+WG GN K+Y+FI R FLA S++++ TTV IDI GE+F G +L+ YL+VYP+++ +DK I Y+ E F P IDL G+T P+ +TEA+L++ MD + IGTDAT A HI+TI++R YV + N+FVP LG++L Y+ MGFE SKP+LR+++EAD+ I G K + VL I YK ++++A Q++ D + +Y
Sbjct: 100 KKTLEREIKKADILILWLDCDREGENIAFEVLEVCKNAKKKFEFYRAHFSAIIPREIDRACKNLAKPNEKDSIAVDTRMEIDLRIGAAFTRFQTLYL-KKFKIISNSDNQPKTTTPANGNILNNSNNNSSGKEIISYGPCQFPTLGFVVERYFRIVNFKPEDFWHL-SVVHEKMDTSSGKMIPVTFSWCRNRLFDYTAAFILYEKCLDNTEATVVDVTSK-ESRYRPVPLTTIELQKAASKKLRISSVQTMQYAEELYTKGLISYPRTETDSFQAGTDLKGLIGNQASNPEWGAYASRLINNNQFVYPKSGKNNDNSHPPIHPTSSATGLSGNLKKIYDFITRRFLACCSEESVFANTTVTIDIQGERFSETGTMVLKLGYLEVYPFDKRNDKLIPTYQKGERFTPKRIDLTKGTTVAPHYITEAELLTAMDNNKIGTDATMATHIQTIQDRFYVKKNESNQFVPSNLGVSLVASYELMGFEFSKPNLRAAIEADVDKISRGQKTKQEVLLSTIEKYKQLYQLANQNINCFDRSFREY 634
BLAST of EMLSAG00000003780 vs. SwissProt
Match: gi|667467227|sp|C7J0A2.1|TOP3A_ORYSJ (RecName: Full=DNA topoisomerase 3-alpha) HSP 1 Score: 402.134 bits (1032), Expect = 8.496e-126 Identity = 214/527 (40.61%), Postives = 302/527 (57.31%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPSLAEQ------LISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG-------------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQDN-RFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRDSND 508
++TLE EA C+WL++W D DREGENI +E+ ++C RL + RA+FS + I A++ L P++ + AVD RQ++DLRIGA+FTRFQT+ L F L + ++SYG CQFPT+GF+VER+ I+A PE FW I +H + F W R LFD + V +++C E P+A V++ +++ K K+ P PL T+EL+K ASR +S++ TM+ AE+LY +GFISYPRTET+ + +L ++V Q P WG N KLYE +VRHFLA S+ A+G ETTV IDI GE+F G +L +NYL VY ++ W + Y + ++F PT++ L +G T PP LL EADL+ MDK GIGTDAT +HI+ + +R Y N RF P LG AL GYD MG+E+ KP+LRS +EAD+K++ GTK VL+ + K F A + K+ +A + S R N+
Sbjct: 108 KRTLEEEARKCQWLVLWLDCDREGENIAYEVIDICAGANSRLNIWRARFSALIDREIHEAVQHLDRPNKLFADAVDARQEIDLRIGASFTRFQTMLLKDAF-VLDDTGDDRNIILSYGPCQFPTLGFIVERFWEIQAHEPEEFWTIN-CSHTSDEGTASFGWIRGHLFDYSSAVVIYEMCVEEPMATVQNVRNQEKLKYPPYPLSTIELQKRASRYFRMSSEHTMKVAEELYQAGFISYPRTETDNFSPNTDLHSIVHEQVAHPNWGTYAQRLLDPEARLWRNPSNGGHDDKAHPPIHPTKFSAGETNWTDNHKKLYELVVRHFLACCSQPAVGAETTVEIDIAGEQFNASGRVVLAKNYLDVYRFDSWGGTLLPTYIIGQQFVPTTLTLDSGMTRPPPLLAEADLLGCMDKAGIGTDATMHDHIKKLLDRCYATKDANTRFSPTNLGEALVMGYDEMGYELWKPYLRSMMEADMKSVSIGTKSKSEVLENCLQQMKACFLDARANKVKLFDAMGTFFARSSRPVNE 632
BLAST of EMLSAG00000003780 vs. SwissProt
Match: gi|6686026|sp|O60126.2|TOP3_SCHPO (RecName: Full=DNA topoisomerase 3; AltName: Full=DNA topoisomerase III) HSP 1 Score: 385.185 bits (988), Expect = 7.196e-123 Identity = 208/531 (39.17%), Postives = 305/531 (57.44%), Query Frame = 0
Query: 22 ADVLSRGSANRKTL----EREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPSLAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWGG----------------------------------------NEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERW-SDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQDNR------FVPGQLGIALCDGYDAMGFE--MSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYL 499
A +++ S N + L ++EA N ++L IWTD DREGE+IG EI V P ++V+RA F+ + R I +A + + + + AVD R +LD R+GA FTR QT++L K F L ++ISYG CQFPT+GFVV+R++ +E FVPE +W ++ V T ++F+W+R ++FD+ T + + C E AKV + KPK+K++PLPL TVEL KL + L ISAK T++ AE LYT+GF+SYPRTET+ + +NL +++ T + +W + K+YE I R FLA S +A G ET V + + E F G + E+NYL+VYPYE+W S ++ Y + EEF+P +D++ STS P+ +TE +LI+LMD +GIGTDAT AEHIE ++ R YV + R FVP LG+AL GYD +G E ++KP LR +E LK I G V++ + +++VF + Q + +C YL
Sbjct: 85 AQIITSVSKNAEVLADNIKKEARNAQYLYIWTDCDREGEHIGVEISNVARASNPSIQVIRADFNNLERSHIISAAKRPRDVSKNAADAVDARIELDFRLGAIFTRLQTIQLQKSFDILQNKIISYGPCQFPTLGFVVDRWQRVEDFVPETYWHLRFVDKRQGKT-IQFNWERAKVFDRLTTMIILENCLECKTAKVVNITQKPKTKYKPLPLSTVELTKLGPKHLRISAKKTLELAENLYTNGFVSYPRTETDQFDSSMNLHAIIQKLTGAQEWDSYAEGLLAGDYRPPRKGKHNDRAHPPIHPVQMVHRSALPSQDHWKVYELITRRFLACCSDNAKGAETLVQVKMEEELFSKKGLLVTEKNYLEVYPYEKWESSDQLPEYRLHEEFQPHILDMMDSSTSSPSYITEPELIALMDANGIGTDATMAEHIEKVQEREYVIKRKKRGQGVTEFVPSSLGVALAKGYDEIGLEWSLTKPFLRKEMEVQLKNIENGQLNRNVLVHMILTQFRDVFHLTKQRFDCLKNSCRVYL 614
BLAST of EMLSAG00000003780 vs. SwissProt
Match: gi|136001|sp|P13099.1|TOP3_YEAST (RecName: Full=DNA topoisomerase 3; AltName: Full=DNA topoisomerase III) HSP 1 Score: 342.813 bits (878), Expect = 3.174e-106 Identity = 204/533 (38.27%), Postives = 289/533 (54.22%), Query Frame = 0
Query: 35 LEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRL----KVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPSLA----------------EQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENT-KVEFSWKRVRLFDQXATQVYHDICTENP--VAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQS--------------------------------PQWGGNEGK-----------------------LYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERW-SDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQ----DNRFVPGQLGIALCDGYDAMGFE--MSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFE 482
++REA N ++L+IWTD DREGE IG+EI + R RL +V RA FS + R I NA R + D K AV R ++DLR G FTR T L K + A Q++SYG+CQFPT+GFVV+R++ I FVPE FW I+ V +N F W R LFD+ + +++ C E VA+V D KSKP +K+RPLPL TVEL+K +R L ++AK ++ AEKLY GFISYPRTET+ +P ++L +LVE Q Q P+ G ++ K +YE++ RHFLA S+DA G+ T+ +D E+F G +LERN+L VYP+ RW + K++ E+ + ++ AG+T+PP +TE++LI LMD +GIGTDAT AEHI+ I+ RNYV + + P LG++L G++A+G E +KP R +E DLK ICEG V+++ + Y+ +
Sbjct: 105 IKREARNADYLMIWTDCDREGEYIGWEIWQEAKR-GNRLIQNDQVYRAVFSHLERQHILNAARNPSRLDMKSVHAVGTRIEIDLRAGVTFTRLLTETLRNKLRNQATMTKDGAKHRGGNKNDSQVVSYGTCQFPTLGFVVDRFERIRNFVPEEFWYIQLVVENKDNGGTTTFQWDRGHLFDRLSVLTFYETCIETAGNVAQVVDLKSKPTTKYRPLPLTTVELQKNCARYLRLNAKQSLDAAEKLYQKGFISYPRTETDTFPHAMDLKSLVEKQAQLDQLAAGGRTAWASYAASLLQPENTSNNNKFKFPRSGSHDDKAHPPIHPIVSLGPEANVSPVERRVYEYVARHFLACCSEDAKGQSMTLVLDWAVERFSASGLVVLERNFLDVYPWARWETTKQLPRLEMNALVDIAKAEMKAGTTAPPKPMTESELILLMDTNGIGTDATIAEHIDKIQVRNYVRSEKVGKETYLQPTTLGVSLVHGFEAIGLEDSFAKPFQRREMEQDLKKICEGHASKTDVVKDIVEKYRKYWH 636
BLAST of EMLSAG00000003780 vs. SwissProt
Match: gi|6686033|sp|O95985.1|TOP3B_HUMAN (RecName: Full=DNA topoisomerase 3-beta-1; AltName: Full=DNA topoisomerase III beta-1) HSP 1 Score: 335.88 bits (860), Expect = 1.878e-101 Identity = 187/506 (36.96%), Postives = 273/506 (53.95%), Query Frame = 0
Query: 33 KTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLK-----VLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPSLAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQW--------------------------------------GGNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEIL-NYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQDN-RFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDE 493
K L+ E C+++++W D D+EGENI FE+ + L V + V RA+FS IT I NA+ L EPD ++ +VD RQ+LDLRIG AFTRFQT K+ L LIS+G CQ PT+GF VER+ I++F PE +W ++ + ++ + W RVR+FD+ Q++ ++ A+VE K K+K RPL L+TVE+ ++AS L + + MQTAE+LYT G+ISYPRTET YP+ +L + Q P W GG+ +LYE+I RHF+A+VS D ++T+ I E F G T+L + +V P++ +E L + + F + ++ T+PP+ LTEA+LI+LM+KHGIGTDA+ HI I RNYV ++ R P LGI L GY + E+ P +RS++E L I +G VL ++ +K F V + +DE
Sbjct: 100 KFLQVEGRGCDYIVLWLDCDKEGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDICNAMACLGEPDHNEALSVDARQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETYWVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRPLALNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANHPYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAWRLYEYITRHFIATVSHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEESLPTCQRGDAFPVGEVKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNLGIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSIAGMDE 605
BLAST of EMLSAG00000003780 vs. Select Arthropod Genomes
Match: gb|EFA08981.1| (DNA topoisomerase 3-alpha-like Protein [Tribolium castaneum]) HSP 1 Score: 577.785 bits (1488), Expect = 0.000e+0 Identity = 304/568 (53.52%), Postives = 377/568 (66.37%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPS-LAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG-------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQDN-RFVPGQLGIALCDGYDAMGFEMS--KPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRDSNDEGFFSMSNESRFTPTLSQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAP 558
++TLERE +C+ LIIWTD DREGENIGFEI +VC V P L++ RAKFSEIT SI AL L +P++ S AVDVRQ+LDLR GAAFTR QTLRL + FP LA++LISYGSCQFPT+GFVVERY+AI+ F+PE FWKIK + H + EF+WKR RLFD+ A + DIC E+P A VE + KPKSKWRPLPLDTVE+EK SRKL I+AK TM+ AEKLYT G ISYPRTETNI+PKELNL+NLV +Q +WG GNE ++YE+IVRHFLA V KDA G ET V DI GEKF G ILE+NYL+VY YE+W+ KEI +Y+ + F P+ ++L G+T+PP LLTEADLI+LM+KHGIGTDATHAEHI+TIK R YVGL +N FVPG LG+ L +GY+ +G E+S KP LR+ E DLK IC+G K PEVV +EQI Y+ VFE V+ +++IDE L + P+ DE + ++ P L KC + T+ + N G+ C P
Sbjct: 97 KRTLEREIRSCQGLIIWTDCDREGENIGFEIIKVCSDVKPNLRIYRAKFSEITAASIFRALNTLGQPNKNVSDAVDVRQELDLRTGAAFTRLQTLRLQRVFPQKLADRLISYGSCQFPTLGFVVERYQAIQDFIPEPFWKIK-MNHTVNDITTEFTWKRDRLFDKNACEAILDICKESPNATVEKVEGKPKSKWRPLPLDTVEMEKTVSRKLKITAKDTMKIAEKLYTQGLISYPRTETNIFPKELNLANLVTLQQNDQRWGAFAHRIMNEGGPAPRQGKKSDQAHPPIHPTKHADNLTGNEQRVYEYIVRHFLACVHKDAQGFETVVTADIAGEKFTAKGLIILEKNYLEVYTYEKWNAKEIHSYQQGDTFIPSVLELYEGATAPPKLLTEADLIALMEKHGIGTDATHAEHIDTIKTREYVGLHENIYFVPGTLGMGLVEGYNNIGLEVSLAKPILRADFEKDLKLICDGLKDPEVVRREQIQKYRAVFETVVEKMRQIDECLANRLADRPQVVEDEHYENVE----VRPVL------KCPKCGNDMTIRNKKNNAGKFISCTGYP 653 HSP 2 Score: 109.768 bits (273), Expect = 1.242e-23 Identity = 76/210 (36.19%), Postives = 104/210 (49.52%), Query Frame = 0
Query: 575 PLPSSSSAXIPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPSTSSFNSNSQPAINDENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGNFNGNDSNFRRPSRDSTVPSRGGGGGLKRSGSTTREGGSDKKKRRCGLCHREGHTRNKCPN 784
P P S SN+++ N I C C A TV+K+G NKGR FY C + C+FF WA ++ PS ++ NSQ +N + C C A ++TVSKEGPNKGR F+ C KP G + C FF+W DE + + G+D + P R + T+R + KR+C C +EGHT+NKCPN
Sbjct: 775 PTPGPSGPSNRSNTTM-NQDDIVCACNLEAVQLTVRKDGPNKGRKFYKC-----KNQTCDFFLWA-------SDEPSNANTTINSQ----QQNDVKCKCDLPASRRTVSKEGPNKGRPFYCCPKPMG--QGCGFFQWADEDNDGGGD--GGPGDDGHGGGPQRRAP------------KTKTSRGAPPYRAKRKCSKCGQEGHTKNKCPN 951 HSP 3 Score: 94.7449 bits (234), Expect = 6.128e-19 Identity = 56/123 (45.53%), Postives = 68/123 (55.28%), Query Frame = 0
Query: 518 SRFTPTLSQT-IKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSSAXIPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWA 639
+R T++Q I C C+L A + TV K+GPNKGRKFY C CDFF W + P S+A NS N + C C A+ RTV KEG NKGR FY CP M +G C FF+WA
Sbjct: 784 NRSNTTMNQDDIVCACNLEAVQLTVRKDGPNKGRKFYKCK-----NQTCDFFLWASDEP----SNANTTINSQQQN--DVKCKCDLPASRRTVSKEGPNKGRPFYCCPKPMGQG--CGFFQWA 893
BLAST of EMLSAG00000003780 vs. Select Arthropod Genomes
Match: EFX74474.1 (hypothetical protein DAPPUDRAFT_324341 [Daphnia pulex]) HSP 1 Score: 573.548 bits (1477), Expect = 0.000e+0 Identity = 295/509 (57.96%), Postives = 352/509 (69.16%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFP-SLAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWGG-------------------------------------NEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQ-DNRFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNE 501
++TLE E ++LIIWTD DREGENIG+E+ VC + P ++V RAKFSEIT SI AL+ L P++ S AVDVR +LDLRIGAAFTRFQTLRL K FP SL + LISYGSCQFPT+GF+VERYKAI+ FV E FWK+K V E +VEF WKR LFDQ Q+ + C ENP A++ ++K KSKWRPLPLDTVELEKLASRKL I+AK TM+ AEKLYT GFISYPRTETNI+PKEL+L+ LV+ QT P WGG NE KLYEFIVRHFLA VSKDA G ET I+I E F+ G I+ RNYL+VYPYERWSD+ + + F PTSI + G TSPP LL+EADLISLM+KHGIGTDATHA+HIETIK+R Y G+Q D RF+P LG+ L GYDAMG +SKP+LR+ LEADLK +C+G + P VL+EQI Y+ VF A++ V KIDEA + NE
Sbjct: 100 KRTLEEETKKSKYLIIWTDCDREGENIGYEVITVCQAIKPNIQVFRAKFSEITYQSIARALQNLGPPNKNVSDAVDVRIELDLRIGAAFTRFQTLRLQKVFPGSLGQSLISYGSCQFPTLGFIVERYKAIQDFVRENFWKLKVVWELNEEERVEFLWKRHHLFDQTVVQILLEKCQENPEAEIIKVQTKNKSKWRPLPLDTVELEKLASRKLRINAKETMKIAEKLYTQGFISYPRTETNIFPKELDLTPLVQCQTVDPAWGGFAQRVLDEGLNPRQGKKSDQAHPPIHPTKYAGNLSNENERKLYEFIVRHFLACVSKDAQGYETVAEIEIQEEGFVASGLQIVARNYLEVYPYERWSDRSLPQLNEGQRFIPTSITMDEGETSPPQLLSEADLISLMEKHGIGTDATHADHIETIKSRQYAGVQGDGRFLPCSLGMGLVQGYDAMGIALSKPNLRAELEADLKRVCDGERNPNDVLREQIERYRRVFVQAMEQVIKIDEALSTFFNE 608 HSP 2 Score: 96.6709 bits (239), Expect = 1.561e-19 Identity = 76/221 (34.39%), Postives = 104/221 (47.06%), Query Frame = 0
Query: 585 PSNSSLSN-XSSITCNCGKV--AAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPSTSSFNSNS--------QPAI------NDENSLTCNCGN----LAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGNFNGNDSNFRRPSRDSTVPSRGGGGGLKRSGSTTREGGSDKKKRRCGLCHREGHTRNKCPN 784
PS S +N S+I C C A TV+KEG N GR FY C + C+FF WA N P+ ++ N QP ND++ C+C LA +T K GPN GR+F+ C+KP +C FFKW D+ S S + SN +D+ RG G G R S+ ++++ R+CG C +EGHTRN CP+
Sbjct: 818 PSGSDNNNGDSAIVCKCRDAPDALLLTVRKEGPNTGRQFYKC---AKQQDGCDFFLWADAA-----NVPAPAAQNGRGGAGEAVFRQPTTRNERRDNDDSETYCDCDGGGRELATTRTTQKPGPNCGRQFYCCAKP--REAQCNFFKWMDDTGASGSGFAQDSRGGSN-----QDTGSRGRGRGRGRGRGKSSDPSTTTERRARKCGNCGQEGHTRNHCPD 1023 HSP 3 Score: 67.781 bits (164), Expect = 1.093e-10 Identity = 54/160 (33.75%), Postives = 69/160 (43.12%), Query Frame = 0
Query: 527 TIKCKCDLF--AAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSSAX-------------IPSNSSLSNXSSIT-CNCG----KVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPSTSSFNSNSQPAINDE 666
I CKC A TV KEGPN GR+FY C G CDFF W D +P+ ++ N N S T C+C ++A RT QK G N GR FY C ++CNFFKW + + S S F +S+ N +
Sbjct: 829 AIVCKCRDAPDALLLTVRKEGPNTGRQFYKCAKQQDG---CDFFLWADAANVPAPAAQNGRGGAGEAVFRQPTTRNERRDNDDSETYCDCDGGGRELATTRTTQKPGPNCGRQFYCC--AKPREAQCNFFKWMDDTGA------SGSGFAQDSRGGSNQD 977
BLAST of EMLSAG00000003780 vs. Select Arthropod Genomes
Match: XP_394050.4 (PREDICTED: DNA topoisomerase 3-alpha [Apis mellifera]) HSP 1 Score: 570.852 bits (1470), Expect = 0.000e+0 Identity = 301/595 (50.59%), Postives = 386/595 (64.87%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPS-LAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQDNRF-VPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRDSNDEGFFSMSNESRFTPTLSQTIKC-KCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSSAXIPSN 587
+KTLE+E C LIIWTD DREGENIGFEI +VC + P +++ RAKFSEIT+ S+ +L+ L EPD+ S AVDVR +LDLRIGAAFTRFQTLRL K FP+ LA+ LISYGSCQFPT+GFVVER+ AIE F E +WKIK V +N VEF W+R +LF++ +++ DIC E P A V+ SKP SKWRPLPLDT+ELEK SRKL+++AK M+ AEKLYT G ISYPRTETNI+PKELNL +LV Q +P WG GNE K+YEF+VRHFLA +S +AIG + V IDI GEKF +G ++E+NYL VY YE+W++++I NY + F+PTSI+++ TSPP LLTEADLI+LMDKHGIGTDATHAEHI+TIK+R YVGL D ++ +PG+LGI L GYD MGF+MSKP LR+ LE DLK ICE K + VL+ QIN Y+++F+I+++ ID A Y +E P + E+ F KC KC L + T+ G+ C P N F Q++++ + + + P N
Sbjct: 98 KKTLEKEVQKCNALIIWTDCDREGENIGFEIIQVCRAIKPNIRIYRAKFSEITQTSVNRSLQNLCEPDKAISDAVDVRSELDLRIGAAFTRFQTLRLRKVFPTTLADMLISYGSCQFPTLGFVVERFLAIEEFKIEPYWKIK-VMDIRDNISVEFKWERGKLFEKLPCEIFLDICLEQPNATVQKISSKPTSKWRPLPLDTIELEKQGSRKLNLNAKEIMRIAEKLYTQGLISYPRTETNIFPKELNLISLVNQQINNPAWGNFAQQLLEKGVNPRKGKKSDQAHPPIHPIKYCDNLNGNEAKVYEFVVRHFLACLSSNAIGHQVIVEIDIAGEKFNANGLQVIEKNYLDVYIYEKWNEQKIHNYREGQVFKPTSIEMIEEKTSPPQLLTEADLITLMDKHGIGTDATHAEHIDTIKSRQYVGLVDEKYLIPGKLGIGLVLGYDNMGFQMSKPGLRAELERDLKLICEQRKNAKEVLENQINKYRDLFKISMERANLIDNALADYFDEQPTKIQEL-------ENNFPSQDIAIFKCPKCGL---DMTLKDRKQGMGKYIGCIGYPTCN-NVIWFPQYIEDVEITDNICSRCPGN 680 HSP 2 Score: 114.775 bits (286), Expect = 3.363e-25 Identity = 76/198 (38.38%), Postives = 98/198 (49.49%), Query Frame = 0
Query: 594 SSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSS--FNNNTPSTSSF-NSNSQPAINDENSLT---CNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGNFNGNDSNFRRPSRDSTVPSRGGGGGLKRSGSTTREGGSDKKKRRCGLCHREGHTRNKCPNN 785
S I CNC + A V+KEG N GR FY C M +RC+FF WA + S NNT S+ N+ ++ +N+ N T CNC LA + V K+GPNKGR F+ C P NE C+FF+W DE + N F N + R + + KR T KR+CG+C EGHTR CP N
Sbjct: 829 SVILCNCNENAIQLIVRKEGPNHGRAFYKCAKPM--NNRCDFFIWAPDNMSGHIQNNTSKDSNLVNTITELNVNNYNVATIVKCNCNQLATTRIVKKDGPNKGRSFYTC--PKNMNESCKFFQWADENVEATCN-NTFQENSKKRFKKDRSEQLQNLQ-----KRPRVVT-------GKRKCGICGIEGHTRRSCPEN 1009 HSP 3 Score: 97.8265 bits (242), Expect = 6.333e-20 Identity = 60/140 (42.86%), Postives = 75/140 (53.57%), Query Frame = 0
Query: 527 TIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSSAXIPSNSS----LSNXSS------------ITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXE-VSSFNNNT 649
I C C+ A + V KEGPN GR FY C PM+ NRCDFF W P + S I +N+S L N + + CNC ++A R V+K+G NKGR FY+CP NM E C FF+WA E V + NNT
Sbjct: 830 VILCNCNENAIQLIVRKEGPNHGRAFYKCAKPMN--NRCDFFIWA-----PDNMSGHIQNNTSKDSNLVNTITELNVNNYNVATIVKCNCNQLATTRIVKKDGPNKGRSFYTCPKNMNES--CKFFQWADENVEATCNNT 960 HSP 4 Score: 57.3806 bits (137), Expect = 1.880e-7 Identity = 36/90 (40.00%), Postives = 47/90 (52.22%), Query Frame = 0
Query: 646 NNNTPSTSSFNSNSQPAIND--ENS-LTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGNFNGNDSNF 732
+NN+ + S N+N D ENS + CNC AI+ V KEGPN GR F+ C+KP N +C FF W + + H N DSN
Sbjct: 805 DNNSINISKINNNEDKIWGDIDENSVILCNCNENAIQLIVRKEGPNHGRAFYKCAKPM--NNRCDFFIWAPDNMSGHIQ--NNTSKDSNL 890
BLAST of EMLSAG00000003780 vs. Select Arthropod Genomes
Match: EAA13910.3 (AGAP010028-PA [Anopheles gambiae str. PEST]) HSP 1 Score: 544.658 bits (1402), Expect = 9.415e-180 Identity = 275/513 (53.61%), Postives = 343/513 (66.86%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPS-LAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKET-TVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQDNRF-VPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRD 505
+KTLERE C LIIWTD DREGENIG+EI EVC V P+L+V RAKFSEIT PSI+ A+ L +PD +Q+ AV+VR +LDLRIGAAFTRFQTLRL K FP ++ L+SYGSCQ PT+GFV +RYK IE F+P+ FWKIK +TH ++ VEF W R RLFD+ + Y +C NP AKV + KPK+KWRP P+DTVELEKL SRKL ++AK M AEKLYT G ISYPRTETN++ ++ L+ LV+ Q S QWG G+E ++YE I RHFLA VS+DA G ET + E+F G I ERNYL+VYPY+RW+ KEI +Y+V FEPT + L GST+ PN+LTEADLI+LM+KHGIGTDATHAEHI TIK R Y+G +D F VPG LG+ L +GY+ M ++ P LR+ LEADLK +CEG K P VL EQI YK V+ I Q + +D A + LN++P++
Sbjct: 125 KKTLEREVRGCSALIIWTDCDREGENIGYEIIEVCRAVKPQLRVFRAKFSEITAPSIKRAIENLVQPDARQNDAVNVRSELDLRIGAAFTRFQTLRLQKSFPQDISNNLVSYGSCQIPTLGFVAQRYKEIENFIPQTFWKIK-LTHTIDDLTVEFHWSRNRLFDKQCCEAYLMLCQTNPTAKVVNVTQKPKNKWRPTPMDTVELEKLGSRKLKMNAKQVMTIAEKLYTQGIISYPRTETNMFTGDMKLAPLVQAQVASDQWGSFAEKVLQWGVNPRNGKKSDQAHPPIHPTKLPTNLSGDEWRVYELIARHFLACVSRDATGSETIVNVVVAEEEEFTASGLCIHERNYLEVYPYDRWNAKEIHSYQVGHTFEPTELGLHEGSTTAPNMLTEADLIALMEKHGIGTDATHAEHINTIKERGYIGERDRGFLVPGTLGMGLVEGYEMMELRLAHPELRAGLEADLKLVCEGRKNPNDVLAEQIAKYKEVYRIMSQKARALDRAMGQRLNQTPQE 636 HSP 2 Score: 65.855 bits (159), Expect = 4.357e-10 Identity = 47/140 (33.57%), Postives = 68/140 (48.57%), Query Frame = 0
Query: 656 NSNSQPAINDENS-LTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDE---VTNSHSNPGNFNGNDSNFRRPSRDSTVPSRGGGGGLKRSGSTTREGG--------SDKKKRRCGLCHREGHTRNKCP 783
+++S+ I +E+ + C CG A + TV K+GPNKGR F+ C S C FFKW DE +S++ S + R ++ TTR+ G +K R+CGLC +EGHT+NKCP
Sbjct: 881 SNSSRVGIGEEDGEVMCRCGTPASRFTVKKDGPNKGRPFFSCPNQASS---CGFFKWGDENMPPASSNNGGTGGGSVSWGSGGVSNSGSSWGRSSNDTTNKTSRTTRKCGLCRQEGHTKNKTTRKCGLCRQEGHTKNKCP 1017
BLAST of EMLSAG00000003780 vs. Select Arthropod Genomes
Match: AAF53813.2 (topoisomerase 3alpha [Drosophila melanogaster]) HSP 1 Score: 547.354 bits (1409), Expect = 2.515e-178 Identity = 279/512 (54.49%), Postives = 341/512 (66.60%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFP-SLAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTE--NPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQDNRF-VPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESP 503
++TLERE C+ LIIWTD DREGENIG+EI +VC + P + V RA FSEIT ++ AL+ L +PD++QS AVDVR +LDLR GAA TRFQT+RL + FP +A++LISYGSCQ PT+GFV ERYK IEAFV E FWKIK V H ++ VEF+W R RLFD+ A + Y +C +P A VE KPK KWRP PLDTVE+EKL SRKL +SAK TM AEKLYT GFISYPRTETN + KE L+ LVEMQT WG GNE ++YE +VRHFLA VSKDA+G ET V IDI GEKF +G I ERNYL VY Y++WS K+I +YE + FEPT + L G+T+ P LLTEADLI+LM+KHGIGTDATHAEHI TIK R Y+G+ D F VPG +G+ L +GYDAM ++KP LR+ E DLK IC+G K P+VVL EQI YK ++ + +D +NE+P
Sbjct: 122 KRTLEREVRGCQGLIIWTDCDREGENIGYEIIDVCRAIKPNISVYRATFSEITTVAVRRALQQLGQPDKRQSDAVDVRTELDLRTGAAITRFQTMRLQRLFPEKIADKLISYGSCQIPTLGFVAERYKEIEAFVSEPFWKIK-VLHTIDDLTVEFNWARNRLFDKEACENYLLLCLAEPDPRALVESVTVKPKHKWRPTPLDTVEMEKLGSRKLKLSAKETMTIAEKLYTKGFISYPRTETNQFSKEFALAPLVEMQTGHRDWGAFAQRVIEWGPNPRNGNKSDQAHPPIHPTKLAENLQGNEARVYELVVRHFLACVSKDAVGSETLVHIDIAGEKFTANGLVIHERNYLDVYVYDKWSAKQIHHYENGQRFEPTEVSLHEGATTAPPLLTEADLIALMEKHGIGTDATHAEHINTIKERGYIGVLDKGFLVPGVIGMGLYEGYDAMELALAKPQLRAEFELDLKLICQGQKDPKVVLTEQIAKYKQAYQQITDKITAMDAKISARINETP 632 HSP 2 Score: 106.686 bits (265), Expect = 1.428e-22 Identity = 78/244 (31.97%), Postives = 106/244 (43.44%), Query Frame = 0
Query: 588 SSLSNXSSITCN-CGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSF---NNNT----PSTSSFNSN---SQPAINDENS-------------------------------------LTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGNFNGNDSNFRRPSRDSTVPSRGGGGGLKRSGSTTREGGSDKKKRRCGLCHREGHTRNKCP 783
SS+ ++ C C + A TV+K G N GR +Y CP + CNFF+WA E S N+T ST+S+ SN + P+I NS + CNCG LA + TV K+GPN+GR F+ C + C FFKW DE N ++ ++ + N S+ + + S G K RRCGLC +EGHTRNKCP
Sbjct: 1025 SSVPESETVLCTGCQQPARQNTVRKNGPNLGRLYYKCP----KPDECNFFQWADEPPSSAKSKNSTGSAPQSTTSWGSNRVVTLPSIQQSNSQRGQSSMRSNSSSTVTITQTKTKQQERNTATPGDGEEVMCNCGQLASQLTVRKDGPNQGRPFYACPT---REKSCGFFKWGDEDQNQGASSTSWGSANRNPPGRSQPTAITSDG------------------PKTRRCGLCRKEGHTRNKCP 1243
BLAST of EMLSAG00000003780 vs. Select Arthropod Genomes
Match: EEB15349.1 (DNA topoisomerase 3-alpha, putative [Pediculus humanus corporis]) HSP 1 Score: 523.087 bits (1346), Expect = 7.941e-173 Identity = 266/506 (52.57%), Postives = 343/506 (67.79%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFP-SLAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQDNR-FVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYL 499
+ L+ E C+ LIIWTD DREGENIGFEI +VC +V P +K+ RAKFSEIT S+ A+ L P++ S AVDVR +LDLRIGAAFTRFQ+L L KKFP + ++SYGSCQFPT+GFVVER+K I F+ E FW+I+ + +N V+F+W+R R+FD+ +V +D C E+ +AKV SKPKSK+RP PLDTVELEKLAS+KL I+AK+ ++TAEKLYT G+ISYPRTETNI+PKEL+L LV+ QT WG G E +YE IVRHFLA +SK+A G ET V ID+ E F G I RNYL VYPY+ W+ KEI Y V + F+P ++ LV G T+PP LLTEADLI+LM+KHGIGTDATHA+HIETIK R YVGL++++ FVP LG+ L +GY+ +GFEM+KP+LR+ LEADL +I K+P+ VL + IN YKN+FE+ + + + E Y+
Sbjct: 97 QNNLKNEVKYCDTLIIWTDCDREGENIGFEIIDVCKKVKPNIKIYRAKFSEITSASVMRAINNLEMPNKSLSDAVDVRMELDLRIGAAFTRFQSLYLQKKFPDNFKSTVVSYGSCQFPTLGFVVERFKNISQFISEPFWRIEVKDNSNKNLIVDFNWERNRMFDKSCCEVLYDKCIESNLAKVIKVDSKPKSKYRPKPLDTVELEKLASKKLKINAKLALKTAEKLYTQGYISYPRTETNIFPKELDLRPLVQRQTTDSNWGEFALKVLVDGPNPNQGTKSDQAHPPIHPIKYASNLTGVEKNIYELIVRHFLACLSKNAEGIETAVEIDLANEIFTAKGLMITARNYLDVYPYDVWNAKEINLYNVGDVFKP-AVSLVEGKTNPPELLTEADLIALMEKHGIGTDATHADHIETIKARFYVGLKNDKYFVPRTLGMGLVEGYNNVGFEMAKPNLRAELEADLSSITRNEKMPQDVLNKHINKYKNIFEVVKTNSKNLFEIINSYI 601 HSP 2 Score: 74.3294 bits (181), Expect = 1.105e-12 Identity = 44/120 (36.67%), Postives = 61/120 (50.83%), Query Frame = 0
Query: 598 CNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAX---EVSSFNNNTPSTSSFNSNSQPAIN---DENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKW 711
C C A R V K G N G+ FY+C N ++CNFF+WA + + NN + N + ++ D N + C+C K V+KEGPNKG+ F+VC + KC FFKW
Sbjct: 783 CFCQLPAISRVVTKLGQNHGKLFYTCN-NQNISNKCNFFQWALPDGQTGNHANNNTREKTTKKNVKSTVSKTKDTNVVKCHCSVSTKKCVVNKEGPNKGKSFFVCGNK-NIDGKCNFFKW 900 HSP 3 Score: 70.4774 bits (171), Expect = 1.783e-11 Identity = 43/126 (34.13%), Postives = 59/126 (46.83%), Query Frame = 0
Query: 529 KCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSSAXIPSN---------------SSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWA 639
KC C L A + V K G N G+ FY CN + +N+C+FFQW LP + +N S + + + C+C V KEG NKG+ F+ C +G +CNFFKWA
Sbjct: 782 KCFCQLPAISRVVTKLGQNHGKLFYTCNN-QNISNKCNFFQWA----LPDGQTGNHANNNTREKTTKKNVKSTVSKTKDTNVVKCHCSVSTKKCVVNKEGPNKGKSFFVCGNKNIDG-KCNFFKWA 901
BLAST of EMLSAG00000003780 vs. Select Arthropod Genomes
Match: gb|KPM11970.1| (DNA topoisomerase 3-alpha [Sarcoptes scabiei]) HSP 1 Score: 462.611 bits (1189), Expect = 3.249e-153 Identity = 252/493 (51.12%), Postives = 318/493 (64.50%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPSLAEQ--LISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICT--ENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWGG-------------------------------------NEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQDNRFV-PGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFE 482
++TL+RE C LIIWTD DREGENIGFEI +VC V P ++LRA FSEIT +I AL +LTEPD++ S AVDVRQQLDLRIGAAFTRFQT+ L K P+ + +ISYGSCQFPT+GFVVER+KA E+FVP+ FW I+ VT + K F+W R RLF++ A T E AKV + + K+RP+ +DTV LE+LAS KL I+AK M AEKLYTSGFISYPRTETN +P E+ L++LV Q +PQWG +E +YE I RHFLA KDA G+E ++ I I+ E F G I ERNYL+VYPYE+W +K I ++ E F P +I + G T+ P LLTEA LI+LM+K+GIGTDATHAEHIE IK R Y+ + R + P LGI L +GYD +G++MSKP LR++LE +L+ IC+G K + VLQ Q+N YK VFE
Sbjct: 100 KRTLQREIRRCAALIIWTDCDREGENIGFEIIKVCQEVNPNFRILRAHFSEITSHAIYRALNSLTEPDKRISDAVDVRQQLDLRIGAAFTRFQTIELQKLRPNSNSEKSIISYGSCQFPTLGFVVERWKARESFVPQPFWFIE-VTVTKDGIKCTFNWHRQRLFNERACFSILARITEPERIEAKVIKVNHQRRLKYRPVAMDTVTLERLASSKLRINAKRAMTIAEKLYTSGFISYPRTETNKFPPEIKLNDLVSAQLDNPQWGSFAQRILSNGGATPRNGKKTDQAHPPIHPTKAAKNLKQDEKLIYELITRHFLACCDKDATGQEESIEIKIDEEIFKLKGLRIEERNYLEVYPYEKWFNKLIPKFQQDEVFVPDAIMMNEGKTTAPELLTEAQLIALMEKNGIGTDATHAEHIEKIKERKYISETETRHLKPEGLGIGLVEGYDEIGYQMSKPFLRAALEKELQQICDGKKNADQVLQNQLNEYKKVFE 591
BLAST of EMLSAG00000003780 vs. Select Arthropod Genomes
Match: gb|EEC11810.1| (DNA topoisomerase III, putative [Ixodes scapularis]) HSP 1 Score: 423.32 bits (1087), Expect = 3.279e-137 Identity = 235/499 (47.09%), Postives = 312/499 (62.53%), Query Frame = 0
Query: 24 VLSRGSAN----RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFP-SLAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEK----LASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSN--LVEMQTQSPQWGGNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEK------FIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQ-DNRFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPR 504
++S G N ++TLE+E C+ L+IWTD DREGENIGF+I VC +V PR++V RA+FSEIT ++ A + L +PD K + AV+VR++LDLRIGAAFTR QTLRL ++FP L ++L+SYGSCQFPT+GFVVERY+ I FVPE FWKI +TH+ ++ +FSWKR RLFD + + C + V+ V + K KPKSKWRP P+DTV + L + L +V TS + RT + + +L+ L + +P +F R ++ K I+ K F+ G I RNYL VYPY++WS KEI NYE+ E F P + LV G TSPP LL EADLI+LM+KHGIGTDATHA+HIET+KNR YV L D VPG+LG+ L +GYD+MG EMSKP LR+ LEADLK IC+GTK P+ VL+ QI Y++VF + + ++K+ E+ KYL R
Sbjct: 132 IMSCGDKNYEKIKETLEKEIRYCDALVIWTDCDREGENIGFQIISVCRKVKPRVRVYRARFSEITPQAVARACQNLADPDPKLNAAVEVRRELDLRIGAAFTRLQTLRLKREFPQQLHDRLVSYGSCQFPTLGFVVERYRQILNFVPEPFWKIH-LTHKKDDILADFSWKRHRLFDYQLCFLLYQRCLQGEVSVVVEMKCKPKSKWRPQPMDTVVSGEAPFYLGASSLSNCWRVLRNPG----TSDQLPGSRTTCGMIRRLRHLTRNVLTSALSSAPA---------DFARRLLADGLTPRQGTKSDQAHPPIHPIKHAASLEFVATGLIIFARNYLDVYPYDKWSAKEIPNYEMNETFVPDQLKLVDGETSPPPLLKEADLIALMEKHGIGTDATHADHIETVKNRLYVALTGDGYLVPGELGMGLVEGYDSMGLEMSKPRLRAELEADLKKICDGTKNPKDVLRRQIELYEDVFSNSERQIKKLGESLKKYLGTGQR 616
BLAST of EMLSAG00000003780 vs. Select Arthropod Genomes
Match: gb|EFA01746.1| (DNA topoisomerase 3-beta-like Protein [Tribolium castaneum]) HSP 1 Score: 330.102 bits (845), Expect = 1.007e-99 Identity = 189/504 (37.50%), Postives = 265/504 (52.58%), Query Frame = 0
Query: 35 LEREASNCEWLIIWTDGDREGENIGFEIREVCLR-----VAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPSLAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG----------------GNEG----------------------KLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEIL-NYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQDNR-FVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDE 493
L EA C++L++W D D+EGENI FE+ R V RA+FS IT I+ A L P+E ++++VD RQ+LDLRIG AFTRFQT ++ L LISYG CQ PT+GF V+R+ I+ F PEA+W IK + V WKRVR FD+ ++ + AKV + SK K+K RP+ L+TVEL ++AS L + MQ AEKLYT G+ISYPRTET YP+ +L ++ Q S +WG G++ KLY++I RHF+ ++++D TT I IN E F G T+L+ + V ++ EI+ N E + L TSPP+ LTEA+LI+LM+ HGIGTDA+ HI I RNYV + R P LGI L GY + E+ P +RS++E L I G + VL+ + +K F+ V+++ +D+
Sbjct: 101 LSHEAKGCDYLVLWLDCDKEGENICFEVMNSVARSMNGDVYSDKVTFRARFSAITDKDIKAAFNNLAHPNENEARSVDARQELDLRIGCAFTRFQTKFFQGRYGDLDSSLISYGPCQTPTLGFCVQRHDQIQTFKPEAYWVIKATIVTKDGNDVHLDWKRVRCFDKEVANMFLQQIKDQKHAKVLNVSSKEKAKSRPVALNTVELMRVASSGLGMGPHHAMQIAEKLYTQGYISYPRTETTRYPENFDLVGVLRQQQNSTEWGDEVREILSRGVNRPKQGHDAGDHPPITPMKSATRNEFDSDSWKLYDYITRHFIGTLARDCKYLSTTATIAINEEIFTVTGKTLLDPGFTSVMTWQALDKNEIVPNLTENESVPIKDMRLTEHQTSPPDYLTEAELITLMETHGIGTDASIPVHINNICQRNYVTVTAGRKLKPTTLGIVLVHGYQKIDAELVLPTMRSAVEEQLNLIALGKANFQAVLRHTVEIFKLKFQYFVKNIDGMDQ 604
BLAST of EMLSAG00000003780 vs. Select Arthropod Genomes
Match: XP_625165.1 (PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Apis mellifera]) HSP 1 Score: 325.865 bits (834), Expect = 3.168e-98 Identity = 183/503 (36.38%), Postives = 273/503 (54.27%), Query Frame = 0
Query: 35 LEREASNCEWLIIWTDGDREGENIGFE-IREVCLRVAPRLK---VLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPSLAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG--------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERW-SDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQDNR-FVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDE 493
L +E ++C++L++W D D+EGENI FE I V + RL + RA+FS IT I++AL L +P+E ++K+VD RQ+LDLRIG AFTRFQT K+ L LISYG CQ PT+GF V+R+ I+ F P+ +W ++ + + +W RVR FD+ ++ E A + +S K+K RP+ L+TVEL ++AS L + MQ AE+LYT G+ISYPRTET +YP+ +L ++ Q +P WG G+ +LY++I RHF+A+++ D TT+ +I E F +G ++L+ Y + ++ S+ + + E+ I LV T PP+ LTE++LISLM+KHGIGTDA+ HI I RNYV + R VP LGI L GY + E+ P +RS++E L I G VLQ + +K F V++++ +D+
Sbjct: 101 LAKEGAHCDYLVLWLDCDKEGENICFEVIYAVQQGMNKRLNPNDIWRARFSAITEKDIKSALVNLIKPNENEAKSVDARQELDLRIGCAFTRFQTKFFQGKYGDLDVSLISYGPCQTPTLGFCVQRHDEIQTFKPDPYWVLQVTVKSSDGQDIILNWTRVRSFDKEIANMFLSHVKEYDQATIISVESTEKTKSRPIALNTVELMRVASSGLGMGPHHAMQIAERLYTQGYISYPRTETTLYPENFDLLAALKQQQNNPDWGDQVRKILTTGINRPKKGCNVGDHPPITPMKHATRNELDGDTWRLYDYITRHFIATLAHDCKYLSTTIKFEIGMEIFTANGHSLLDPGYTSILTWQALGSNDNLPRFTPGEKVNIQEIKLVECYTQPPDYLTESELISLMEKHGIGTDASIPVHINNICMRNYVNVATGRKLVPTSLGIVLVHGYQKIDPELVLPTMRSAVEEQLNLIALGRADFHAVLQHTVEIFKQKFHYFVKNIEAMDQ 603
BLAST of EMLSAG00000003780 vs. nr
Match: gi|1012124701|ref|XP_016000667.1| (PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Rousettus aegyptiacus]) HSP 1 Score: 722.235 bits (1863), Expect = 0.000e+0 Identity = 411/858 (47.90%), Postives = 506/858 (58.97%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPS-LAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG-------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQ-DNRFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRDSNDEGFFSMSNES-RFTPTLSQTIKCKCDLFAAEKTVVKEG---PNKGRKFYCC---------------------------NAPMS------GANRCDFFQWVDEPP------LPSSSSAX-IPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPSTSSFNSNSQ----PAI-----------NDENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGNFN-----GNDSNFRRPSRDSTVPSRGGGGGLKRSGSTTREGGSDKKKRRCGLCHREGHTRNKCPNNR 786
+KTLERE C+ L+IWTD DREGENIGFEI VC V P ++VLRA+FSEIT ++ A LTEPD++ S AVDVRQ+LDLRIGAAFTRFQTLRL K FP LAEQLISYGSCQFPT+GFVVER+KAI++FVPE F KIK VTH++ + VEF+WKR RLF+ A V + +C E+P+A V + SK KSKWRP LDTVELEKLASRKL I+AK TM+ AEKLYT G+ISYPRTETNI+P++LNL+ LVE Q P+WG G+E +LYEFIVRHFLA S+DA G+ETTV IDI E+F+ HG IL RNYL VYPY+RWSDK + YE F+P+++++V G TSPP LLTEADLI+LM+KHGIGTDATHAEHIETIK R YVGL D RF+PG LG+ L +GYD+MG+EMSKP LR+ LEADLK ICEG K VVL++Q+ YK VF AV +K+DEA +Y E + E + E R P ++ + K K K G P +F C N P S NR + Q P PS + A +P S+ +S+TCNCG+ A TV+KEG N+GR FY C G CNFF WA TPS++S + P + ND + C C A+K TV K+GPNKGR+F CSKP ++C FF+W DE + PG F G+ + P S P S++ G + KK R+C LCH+ GHTR CP NR
Sbjct: 130 KKTLERETRQCQALVIWTDCDREGENIGFEIIHVCKAVKPTIQVLRARFSEITPRAVRMACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQKIFPEVLAEQLISYGSCQFPTLGFVVERFKAIQSFVPEIFHKIK-VTHDHRDGIVEFNWKRHRLFNHTACLVLYQLCMEDPMATVVEVSSKAKSKWRPQALDTVELEKLASRKLKINAKETMRIAEKLYTQGYISYPRTETNIFPRDLNLTALVEQQIPDPRWGAFAQSILERGVPTPRNGNKSDQAHPPIHPTKYTNSLQGDEQRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLVILARNYLDVYPYDRWSDKTLPIYERGSRFQPSTVEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAEHIETIKARTYVGLTPDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICEGKKDKFVVLRQQVQKYKQVFIEAVAKAKKLDEALSQYFGEGAEVAQQEAIYPTVPEPIRKCPQCNKDMVLKTKKNGGLKLKFKRGSLPPTMPLEFVGCIGGCDETLREILDLRFSRGTSRTCQPANQPSSHLQANQSLNRINSSQHSHILPPDTRHTRPSKALAQNLPLPSTAGESNSVTCNCGQEAILLTVRKEGPNQGRQFYKC-----HGGSCNFFLWADSSHPEAGRTPSSTSRPLDGSLGHPPGLGKYPGGFGNPGNDGGGMACLCSQPAVKLTVQKDGPNKGRQFHTCSKP--REQQCGFFQWVDE----NVAPGTFGALPWPGSRGKTQGPESRSKRP----------RASSSDTGSTAKKTRKCSLCHQPGHTRPFCPQNR 965
BLAST of EMLSAG00000003780 vs. nr
Match: gi|1016645059|ref|XP_016051963.1| (PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Miniopterus natalensis]) HSP 1 Score: 709.909 bits (1831), Expect = 0.000e+0 Identity = 399/856 (46.61%), Postives = 504/856 (58.88%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPS-LAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG-------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQ-DNRFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRDSNDEGFF-SMSNESRFTPTLSQTIKCKCDLFAAEKTVVKEG---PNKGRKFYCC---------------------------NAPMSGANRCDFFQWVD-------EPP-----LPSSS-SAXIPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPSTSSFNSN----------------SQPAINDENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDE-VTNSHSNPGNFNGNDSNFRRPSRDSTVPSRGGGGGLKRSGSTTREGGSDKKK-RRCGLCHREGHTRNKCPNNR 786
+KTLERE C+ L+IWTD DREGENIGFEI VC V P L+VLRA+FSEIT ++ A LT+PD+K S AVDVRQ+LDLRIGAAFTRFQTLRL K FP LAEQLISYGSCQFPT+GFVVER+KAI+AFVPE F KIK VTH++ + VEFSWKR RLF+ A V + +C E+PVA V + SK KSKWRP LDTVELEKLASRKL I+AK TM+ AEKLYT G+ISYPRTETNI+P++LNL+ LVE QT P+WG G+E ++YEFIVRHFLA S+DA G+ETTV I I+ E F+ HG IL RNYL VYPY+RWSDK + YE F+P+++++V G TSPP LLTEADLI+LM+KHGIGTDATHAEHIETIK R YVGL D RF+PG LG+ L +GYD+MG+EMSKP LR+ LEADLK ICEG K VVL++QI YK VF AV +K+DEA +Y + E + ++ R P ++ + + K K G P +F C + P + +D +PP PS + S +P ++ +S+ CNCG+ A TV+KEG N+GR FY C + C+FF WA TPS++S + +P + +C C A+ +TV K+GPNKGR+F C+KP ++C FF+W DE + S + G P S KR+ +++ + GS KK R+C LCH+ GHTR CP +R
Sbjct: 130 KKTLERETRQCQALVIWTDCDREGENIGFEIIHVCKAVKPSLQVLRARFSEITPRAVRMACENLTKPDQKVSDAVDVRQELDLRIGAAFTRFQTLRLQKIFPQVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPEVFHKIK-VTHDHRDGIVEFSWKRHRLFNHTACLVLYQLCMEDPVATVVEVSSKAKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYISYPRTETNIFPRDLNLTALVEQQTPDPRWGTFAQSILERGGPTPRNGNKSDQAHPPIHPTKYTSSLQGDEQRVYEFIVRHFLACCSEDAQGQETTVEIVISQEHFLAHGLIILARNYLDVYPYDRWSDKTLPVYERGSRFQPSTVEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVGLTPDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICEGRKDKFVVLRQQIQKYKKVFTEAVAKAKKLDEALSQYFGQGAEVPQQEAIYPALPEPIRKCPQCNKDMVLRTKKSGGLKLKFKRGSLPPTMPLEFVGCIGGCDENLREILNLRFSQGPARACPPTSQPSGYLKASQYLNRMDSNQHSHPQPPDTRETRPSKALSRNLPPPAAAGESNSVICNCGQEAVLLTVRKEGPNQGRQFYKC-----QAGSCSFFLWADSGHPEAGGTPSSASRHPGGSLGRPPDSRNPRGGFGRPGDDTGGGTSCLCSQAAVTRTVQKDGPNKGRQFHTCAKP--REQQCGFFQWADENLAPGTSGAAPWPGGRGETHAPESRS-----------KRARASSSDPGSTAKKLRKCSLCHQPGHTRPFCPQSR 966
BLAST of EMLSAG00000003780 vs. nr
Match: gi|836709251|ref|XP_012789147.1| (PREDICTED: DNA topoisomerase 3-alpha [Sorex araneus]) HSP 1 Score: 682.559 bits (1760), Expect = 0.000e+0 Identity = 398/898 (44.32%), Postives = 508/898 (56.57%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPS-LAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG-------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQ-DNRFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRDSNDEGFF-SMSNESRFTPTLSQTI------------------KCKCDLFAAEKT-----------VVKEGPNKGRKFYCCNAPMSGANRCDFFQWV---DE------------PPLPSS-----SSAXIPSNSSLSNXSSITC------NCGKVAAYRT--------------------------VQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTP---------STSSFNSNSQP-----AINDENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGNFNGNDSNFRRPSRDSTVPSRGGGGGLKRSGS--------TTREGGSDKKKRRCGLCHREGHTRNKCPNNR 786
+KTLERE C+ LIIWTD DREGENIGFEI VC V P L VLRA+FSEIT +++ A LTEPD++ S AV+VRQ+LDLRIGAAFTRFQTLRL + FP LAEQLISYGSCQFPT+GFVVER+KAI+AFVPE F +IK VTH++ + +EF+WKR RLF+ A V + +C E+P A V D +SKPKSKWRP LDTVELEKLASRKL I+AK TM+ AEKLYT G+ISYPRTETNI+PK+LNL+ LVE QT P+WG G+E +LYEFIVRHFLA S+DA G+ETTV IDI E+F+ HG IL RNYL VYPY+ WSDK + YE F+P+++++V G TSPP LLTEADLI+LM+KHGIGTDATHAEHIETIK R YVGL D RF+PG LG+ L +GYD+MG+EMSKP LR+ LEADLK ICEG K VVL++Q+ YK VF AV +K+DEA +Y + + E F+ +M R P + + +C+ L+ + V + P KF + +F + DE PPLP+S S+ + ++ +L+ S C N G+ A +T V+KEG N+GR F+ C C+FF WA + P S + + P +S +C C A+ +TV KEGPNKGR+F C+KP ++C FF+W DE + PG T+P GG ++ S + ++ G ++ R+C LCH+ GHTR CP NR
Sbjct: 35 KKTLERETRQCQALIIWTDCDREGENIGFEIIHVCKAVKPSLHVLRARFSEITLRAVQAACENLTEPDQRVSDAVEVRQELDLRIGAAFTRFQTLRLQRIFPEVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPEVFHRIK-VTHDHTDGTIEFNWKRHRLFNHTACLVLYQLCMEDPRATVVDVRSKPKSKWRPQALDTVELEKLASRKLRINAKETMKIAEKLYTQGYISYPRTETNIFPKDLNLAVLVEQQTPDPRWGAFAQSILEQGGPTPRNGNKSDQAHPPIHPTKYASNLQGDEQRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLMILARNYLDVYPYDHWSDKTLPVYEKDSCFQPSTVEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVGLTPDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICEGKKDKFVVLRQQVQKYKQVFIEAVAKAKKLDEALSQYFGDGVEVTPQETFYPAMPEPIRKCPQCGKDMVLKTKKNGGFYVGCVGFPECRSALWFPDSVLEVSRDESVCPVCQPAPVHRLKFKFKRGSLPPTIPLEFVGCIGGCDENLREILDLRFFRPPLPASQPAGQSTGYLQASQALNRMDSGQCGPPQPTNTGRARASKTLAQTLTLPSESNAVTCNCGQEALLLTVRKEGPNQGRQFFKC-----HSGGCSFFLWADSSQPGASGPPPSAARPPGGSLAHLPGSGNPQRGAGGPGGNSSTSCLCSQPAVTRTVQKEGPNKGRQFHTCAKP--REQQCGFFQWVDE----NVAPGTLG-------------TLPWPGGRRKIQESDARNKRPRICSSEMGSEARRPRKCSLCHQPGHTRPNCPQNR 907
BLAST of EMLSAG00000003780 vs. nr
Match: gi|591308452|ref|XP_007080858.1| (PREDICTED: DNA topoisomerase 3-alpha [Panthera tigris altaica]) HSP 1 Score: 677.937 bits (1748), Expect = 0.000e+0 Identity = 386/811 (47.60%), Postives = 491/811 (60.54%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPS-LAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG-------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQ-DNRFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRDSNDEGFFSMSNESRFTPTLSQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSSAXIPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRF---FYSC------------PVNMAEGSRCNFFKWAXEVSSFNNNTPSTSSFNSNSQPAINDEN--SLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGNFNGNDSNFRRPSRDSTVPSRGGGGGLKRSGSTTREGGSDKKK-RRCGLCHREGHTRNKCPNN 785
+KTLERE C+ L+IWTD DREGENIGFEI VC V P L VLRA+FSEIT +++ A LTEPD + S AVDVRQ+LDLRIGAAFTRFQTLRL + FP LAEQLISYGSCQFPT+GFVVER+KAI+AFVPE F KIK VTH++++ VEF+WKR RLF+ A V + +C E+P A V + KSK KSKWRP LDTVELEKLASRKL I+AK TM+ AEKLYT G+ISYPRTETNI+PK+LNL+ LVE QT P+WG G+E +LYEFIVRHFLA S+DA G+ETTV IDI E+F+ HG IL RNYL VYPY+RWSDK + YE F+P+++++V G TSPP LLTEADLI+LM+KHGIGTDATHAEHIETIK R YVGL D RF+PG LG+ L +GYD+MG+EMSKP+LR+ LEADLK ICEG K VVL++Q+ YK VF AV +K+DEA +Y E + E + P + + IK KC K +V + G + C +G C W + L +S + C V + K GS F C + ++ G+ + + S +N+ P++ S N ++ D++ +C C + +TV K+GPNKGR+F C+KP ++C FF+W DE + PG+ G + R R +R KR+ +T+ + GS KK R+C +CH+ GHTR CP N
Sbjct: 130 KKTLERETRQCQALVIWTDCDREGENIGFEIIHVCRAVKPSLPVLRARFSEITPRAVQTACENLTEPDPRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFPEVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPEVFHKIK-VTHDHKDGVVEFNWKRHRLFNHTACLVLYQLCMEDPRATVVEVKSKAKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYISYPRTETNIFPKDLNLTVLVEQQTPDPRWGAFAQSILERGGPTPRNGNKSDQAHPPIHPTKYASSLQGDEQRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLMILARNYLDVYPYDRWSDKTLPVYERGSRFQPSTVEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVGLTPDKRFLPGHLGMGLVEGYDSMGYEMSKPNLRAELEADLKLICEGKKDKLVVLRQQVQKYKQVFVEAVAKAKKLDEALSQYFGEGAEVAQQEAIY---------PAMPEPIK-KCP--QCNKDMVLKTKKSGGFYLSC----TGFPECRSAMWFPDSVLEASRDGTV----------CPVCQPHPVYRLKFKFKRGSLPPTMPLEFVGCVGGCDETLMEILDLRLSRGAP----RASQPASQPSNHLPASQSLNRIARAPWGDDSGGGTSCLCSQPTVTRTVQKDGPNKGRQFHTCAKP--REQQCGFFQWADE----NVAPGSL-GVQTWPRDRGRIQGPEARS-----KRARATSSDTGSTAKKPRKCSVCHQPGHTRPFCPQN 897
BLAST of EMLSAG00000003780 vs. nr
Match: gi|928134541|ref|XP_013969133.1| (PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Canis lupus familiaris]) HSP 1 Score: 677.167 bits (1746), Expect = 0.000e+0 Identity = 381/769 (49.54%), Postives = 467/769 (60.73%), Query Frame = 0
Query: 5 VVKVLNVAEKNXAAKNIADVLSRGSANRKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPS-LAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG-------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGL-QDNRFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRDSNDEGFFSMSNESRFTPTLSQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSS---------------------AXIPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPSTSSFNSNSQPAINDENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTD 713
V K+L VAEKN AAK IAD+LS G RKTL+RE C+ L+IWTD DREGENIGFEI VC V P L+VLRA+FSEIT ++ A LTEPD++ S AVDVRQ+LDLRIGAAFTRFQTLRL K FP LAEQLISYGSCQFPT+GFVVER+KAI+AFVPE F KIK VTH++++ VEF+WKR RLF+ A V + +C E+P A V + +SK KSKWRP LDTVELEKLASRKL I+AK TM+ AEKLYT G+ISYPRTETNI+PK+L+L+ LVE QT P+WG G+E +LYEFIVRHFLA S+DA G+ETTV IDI E+F+ HG IL RNYL VYPY+RWSDK + YE F+P+++++V G TSPP LLTEADLI+LM+KHGIGTDATHAEHIETIK R YVGL D RF+PG LG+ L +GYD+MG+EMSKP LR+ LEADLK ICEG K VVL++Q+ YK VF AV +K+DEA +Y E + E + P++ + IK KC + V+K N G C +G C W + L +S +P L + C G R + ++G S P + N+ + S N T S A + NS+ CNCG A+ TV KEGPN+GR+F+ C C FF W D
Sbjct: 33 VRKILCVAEKNDAAKGIADLLSNGRMRRKTLQRETQQCQALVIWTDCDREGENIGFEIIHVCRAVKPNLQVLRARFSEITPRAVRVACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQKIFPEVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPEIFHKIK-VTHDHKDGIVEFNWKRHRLFNHTACLVLYQLCMEDPTATVVEVRSKSKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYISYPRTETNIFPKDLDLTVLVEQQTPDPRWGAFAQSILERGGPTPRNGNKSDQAHPPIHPTKYTSSLQGDEQRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLMILARNYLDVYPYDRWSDKTLPVYERGSHFQPSTVEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVGLTADKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICEGKKDKSVVLRQQVQKYKQVFIEAVAKAKKLDEALSQYFGEGTEVAQQEAIY---------PSMPEPIK-KCPQ-CNKDMVLKTKKNGGFYLSC-----TGFPECRSAVWFPDSVLEASRDDSVCPVCQPHPVYRLKLKFKRGSLPPTMPL---EFVGCIGGCDETLREILDLRFSRGPPRASQPASQPS----NYL----QASQSQNRTDSAPRMLPLPAAADGESNSVICNCGQEAVLLTVRKEGPNQGRQFYKC-----GGGGCDFFLWAD 768 HSP 2 Score: 120.168 bits (300), Expect = 3.156e-24 Identity = 81/235 (34.47%), Postives = 108/235 (45.96%), Query Frame = 0
Query: 575 PLPSSSSAXIPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPSTSSFNS-----NSQPAINDENS------------LTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGNFNGNDSNFRRPSRDSTVPSRGGG---GGLKRS----GSTTREGGSDKKKRRCGLCHREGHTRNKCPNN 785
PLP+++ +S+ CNCG+ A TV+KEG N+GR FY C G C+FF WA + S+ P S+ PA+ D + C C A+ +TV K+GPNKGR+F C+KP ++C FF+W DE + PG R T P RG G G RS S+ G + KK R+C LCH+ GHTR CP N
Sbjct: 717 PLPAAADG---------ESNSVICNCGQEAVLLTVRKEGPNQGRQFYKC-----GGGGCDFFLWA-DSSALEPRGPPASALGPAGGSLGHPPAMGDRRGGFGRPGDDGGRGMACLCSQPAVTRTVQKDGPNKGRQFHTCAKP--REQQCGFFQWVDE----NVAPGTL-----------RTPTWP-RGRGRTQGPEARSKRARASSADMGSTPKKPRKCSLCHQPGHTRPFCPQN 918 HSP 3 Score: 80.4925 bits (197), Expect = 6.086e-12 Identity = 54/150 (36.00%), Postives = 71/150 (47.33%), Query Frame = 0
Query: 525 SQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVD----EPPLPSSSSAXIPSNSSLSNXSS------------------ITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXE-VSSFNNNTPS 651
S ++ C C A TV KEGPN+GR+FY C G CDFF W D EP P +SA P+ SL + + + C C + A RTVQK+G NKGR F++C +C FF+W E V+ TP+
Sbjct: 726 SNSVICNCGQEAVLLTVRKEGPNQGRQFYKC-----GGGGCDFFLWADSSALEPRGP-PASALGPAGGSLGHPPAMGDRRGGFGRPGDDGGRGMACLCSQPAVTRTVQKDGPNKGRQFHTC--AKPREQQCGFFQWVDENVAPGTLRTPT 867
BLAST of EMLSAG00000003780 vs. nr
Match: gi|985392507|ref|XP_015363553.1| (PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Diuraphis noxia]) HSP 1 Score: 676.781 bits (1745), Expect = 0.000e+0 Identity = 375/800 (46.88%), Postives = 490/800 (61.25%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPS-LAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWGG------------------------------------NEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQDNR-FVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRDSNDEGFFSMSNESRFTPTLSQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSSAXIPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPSTSSFNSNSQPAINDENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGNFN--------GNDSNFRRPSRDSTVPSRGGGGGLKRSGSTTREGGSDKKKRRCGLCHREGHTRNKCPNN 785
+KTL RE +C L+IWTD DREGENIGFEI +VC V PR++V RA SEITRPS++ A+ +L P++ S AVDVR +LDLRIGAAFTR+QT+RL K FP LA+ LISYGSCQFPT+GFVVERYK I+ F+PE FWKIK V H+ EN VEFSW+RVRLFD+ +V ++ C ENP A V KPKSKWRP+PLDT+ELEK ASRKL I+AK TM+ AEKLY+ GFISYPRTETNI+PKELNLSNLV++Q Q WG E K+YE++VRHFLA +SKDA G+ET V I+INGEKF+ +G I+ NYL+VYPY++WS+K+I +Y + F PT ++++ G TSPPNLLTEADLISLMDKHGIGTDATHAEHIETIK+R YVGL++N+ FVPG+LGI L +GYD MGFEMSKPHLR+ LEADLK ICEGTK P VVL+EQI YK+VF + V+K+D++ KYL P + N ++ + I+ KC + V+++ N F C +G C W+ PS A + N S + + + +V+ + + C +N + + C + S ++++ ST N N + + + C CGN A TV++E NKGR+F+ CSKP +N++C FF W ++ + P N + N+ P R + ++ GG +R+CGLC + GHTR CP N
Sbjct: 130 KKTLVREVQSCNALVIWTDADREGENIGFEIIDVCREVNPRIQVYRAILSEITRPSVQRAISSLGAPNKNISDAVDVRSELDLRIGAAFTRYQTMRLQKVFPEVLAKSLISYGSCQFPTLGFVVERYKDIQNFIPEQFWKIK-VHHKIENLDVEFSWQRVRLFDEVLCKVLYERCKENPTALVLKVTKKPKSKWRPVPLDTIELEKAASRKLGINAKETMKIAEKLYSQGFISYPRTETNIFPKELNLSNLVQLQVQDNNWGDFAQNVLNNGPSPRQGKKSDQAHPPIHPTKYTQGLQDRERKVYEYVVRHFLACLSKDAEGEETIVNIEINGEKFLANGLRIIALNYLEVYPYDKWSNKQIHDYNQGQSFMPTELEMIDGQTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKSRLYVGLENNKYFVPGELGIGLVEGYDNMGFEMSKPHLRAELEADLKKICEGTKSPLVVLREQIAKYKDVFIKTTEQVEKLDQSLGKYLRTQP--------IAFQNNAQHESMTVKNIR-KCPVCKQTNLVIRKKQNNQGFFISC----TGFPNCRNTYWLP----PSVIDAQVSDNVC----SQCSGDMKLIKFQFSVRSMRPHYPDTYEGC-INGCDSTLCEILQ--VNTSRPSSSSSSTQPSNRNVVTTNQNRDQVCCQCGNAAKLLTVTRETANKGRQFYGCSKPISANDRCTFFLWANDQPVPAAGPPNTHFNNRNNFQNNNGQINNPYRARIINNQSNSGG----------------QRKCGLCKQPGHTRRNCPRN 888
BLAST of EMLSAG00000003780 vs. nr
Match: gi|985392505|ref|XP_015363552.1| (PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Diuraphis noxia]) HSP 1 Score: 672.929 bits (1735), Expect = 0.000e+0 Identity = 379/828 (45.77%), Postives = 496/828 (59.90%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPS-LAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQDNR-FVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRDSNDEGFFSMSNESRFTPTLSQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSSAXIPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXE----------------VSSFNNNTPS--------TSSF----NSNSQPAINDENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGNFN--------GNDSNFRRPSRDSTVPSRGGGGGLKRSGSTTREGGSDKKKRRCGLCHREGHTRNKCPNN 785
+KTL RE +C L+IWTD DREGENIGFEI +VC V PR++V RA SEITRPS++ A+ +L P++ S AVDVR +LDLRIGAAFTR+QT+RL K FP LA+ LISYGSCQFPT+GFVVERYK I+ F+PE FWKIK V H+ EN VEFSW+RVRLFD+ +V ++ C ENP A V KPKSKWRP+PLDT+ELEK ASRKL I+AK TM+ AEKLY+ GFISYPRTETNI+PKELNLSNLV++Q Q WG E K+YE++VRHFLA +SKDA G+ET V I+INGEKF+ +G I+ NYL+VYPY++WS+K+I +Y + F PT ++++ G TSPPNLLTEADLISLMDKHGIGTDATHAEHIETIK+R YVGL++N+ FVPG+LGI L +GYD MGFEMSKPHLR+ LEADLK ICEGTK P VVL+EQI YK+VF + V+K+D++ KYL P + N ++ + I+ KC + V+++ N F C +G C W+ PS A + N S + + + +V+ + + C +N + + C + V++ N P+ T++F + N+Q ND+ + C CGN A TV++E NKGR+F+ CSKP +N++C FF W ++ + P N + N+ P R + ++ GG +R+CGLC + GHTR CP N
Sbjct: 130 KKTLVREVQSCNALVIWTDADREGENIGFEIIDVCREVNPRIQVYRAILSEITRPSVQRAISSLGAPNKNISDAVDVRSELDLRIGAAFTRYQTMRLQKVFPEVLAKSLISYGSCQFPTLGFVVERYKDIQNFIPEQFWKIK-VHHKIENLDVEFSWQRVRLFDEVLCKVLYERCKENPTALVLKVTKKPKSKWRPVPLDTIELEKAASRKLGINAKETMKIAEKLYSQGFISYPRTETNIFPKELNLSNLVQLQVQDNNWGDFAQNVLNNGPSPRQGKKSDQAHPPIHPTKYTQGLQDRERKVYEYVVRHFLACLSKDAEGEETIVNIEINGEKFLANGLRIIALNYLEVYPYDKWSNKQIHDYNQGQSFMPTELEMIDGQTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKSRLYVGLENNKYFVPGELGIGLVEGYDNMGFEMSKPHLRAELEADLKKICEGTKSPLVVLREQIAKYKDVFIKTTEQVEKLDQSLGKYLRTQP--------IAFQNNAQHESMTVKNIR-KCPVCKQTNLVIRKKQNNQGFFISC----TGFPNCRNTYWLP----PSVIDAQVSDNVC----SQCSGDMKLIKFQFSVRSMRPHYPDTYEGC-INGCDSTLCEILQVNTSRPSSSSSSTQPSNRNVVTTNQNRGPTHENNVHRPTNNFXRPASQNTQLLNNDQ--VCCQCGNAAKLLTVTRETANKGRQFYGCSKPISANDRCTFFLWANDQPVPAAGPPNTHFNNRNNFQNNNGQINNPYRARIINNQSNSGG----------------QRKCGLCKQPGHTRRNCPRN 916
BLAST of EMLSAG00000003780 vs. nr
Match: gi|328710041|ref|XP_001950527.2| (PREDICTED: DNA topoisomerase 3-alpha [Acyrthosiphon pisum]) HSP 1 Score: 671.774 bits (1732), Expect = 0.000e+0 Identity = 382/822 (46.47%), Postives = 488/822 (59.37%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPS-LAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWGG------------------------------------NEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQDNR-FVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRDSNDEGFFSMSNESRFTPTLSQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSSAXIPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFK---------------WAXEVSSFNNNTPSTSSFN--------------SNSQPAINDENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGN-FNGNDSNFRRPSRDSTVPSRGGGGGLKRSGSTTREGGSDKKKRRCGLCHREGHTRNKCPNN 785
+KTL RE +C L+IWTD DREGENIGFEI +VC V PR++V RA SEITRPS++ A+ +L P++ S AVDVR +LDLRIGAAFTR+QT+RL K FP LA+ LISYGSCQFPT+GFVVERYK I+ F+PE FWKIK V H+ EN VEFSW+RVRLFD+ + ++ C ENP A V KPKSKWRP+PLDT+ELEK ASRKL I+AK TM+ AEKLY+ GFISYPRTETNI+PKELNLSNLV++ Q WG E K+YE++VRHFLA +SKDA G+ET V I+INGEKF+ +G I+ NYL+VYPY++WS+K+I NY+ + F PT +++V G TSPPNLLTEADLISLMDKHGIGTDATHAEHIETIK+R YVGL++N+ FVPG+LGI L +GYD MGFEMSKPHLR+ LEADLK ICEGTK P VVL+EQI YK+VF + V+K+D++ KYL P + N ++ + I+ KC + V+K+ N F C +G C W+ PS A + N I K+ ++ + Y +N + + C + V + N N+ T N N QP ND+ + C CGN A TV++E NKGR+F+ C KP +N++C FF W D+ + P N N +N + + P R + + GG +R+CGLC + GHTR CP N
Sbjct: 130 KKTLVREIRSCNTLVIWTDADREGENIGFEIIDVCREVNPRIQVYRAILSEITRPSVQRAISSLGPPNKNISDAVDVRSELDLRIGAAFTRYQTMRLQKVFPEVLAKSLISYGSCQFPTLGFVVERYKDIQNFIPENFWKIK-VHHKIENLDVEFSWQRVRLFDEVLCNILYERCQENPTALVLKVTKKPKSKWRPVPLDTIELEKAASRKLGINAKETMKIAEKLYSQGFISYPRTETNIFPKELNLSNLVQLHVQDNNWGDFAQSVLINGPTPRQGKKSDQAHPPIHPTKYTNGLQDRERKVYEYVVRHFLACLSKDAEGEETIVNIEINGEKFLANGLRIIALNYLEVYPYDKWSNKQIHNYDQGQSFMPTGLEIVDGQTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKSRLYVGLENNKYFVPGELGIGLVEGYDNMGFEMSKPHLRAELEADLKKICEGTKSPLVVLREQIAKYKDVFIKTTEQVEKLDQSLGKYLRTQP--------VAFLNNAQHESMAVKNIR-KCPVCKQTNLVLKKKQNNQGFFISC----TGFPTCRNTYWLP----PSVIDAQVSDNICSECSGGI-----KLVKFQFSARSMRPHYPDTYEGCINGCDSTLCEILQVNMSRSSSSSSSTQRSNRNVITTNQNSGHTRENNVRLPMNNLSRPGSSQNPQPLNNDQ--VCCQCGNAAKLLTVTRETANKGRQFYGCPKPISANDRCTFFLWADDQPMPTAGPPNTQFNNRNNHQNNNGQMNNPYRA-------RNNQSNSGG----QRKCGLCKQPGHTRRNCPQN 915
BLAST of EMLSAG00000003780 vs. nr
Match: gi|395517927|ref|XP_003763121.1| (PREDICTED: DNA topoisomerase 3-alpha, partial [Sarcophilus harrisii]) HSP 1 Score: 663.3 bits (1710), Expect = 0.000e+0 Identity = 399/893 (44.68%), Postives = 495/893 (55.43%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPS-LAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG-------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGL-QDNRFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRDSNDEGFFSMSNESRFTPTLSQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSS---------------------AXIPSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPSTSSFNSNSQ----------PAINDE--NSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTD-----EVTNSH--SNPGNFNGNDSN-----------------FRRPSRDSTVPSRGGGGGLK-RSGSTTREG-------------------------GSDKKKRR----------------CGLCHREGHTRNKCPNNR 786
+KTLE+E C+ L+IWTD DREGENIGFEI VC V P L+V RA+FSEIT +++ A + LTEPD++ S AV+VRQ+LDLRIGAAFTRFQTLRL K FP LAEQLISYGSCQFPT+GFVVER+KAI+AFVPE F KIK VTHE+E+ V+FSWKR RLF+ A V + +C E+PVA V + SKPKSKWRP PLDTVELEKLASRKL I+AK TM+ AEKLYT G+ISYPRTETNI+PK+LNL+ LV+ QT QWG GNE +LYEFIVRHFLA S+DA+G+ETTV IDI E+F+ HG IL RNYL VY Y++WSDK I YE F+PT+I++V G TSPP LLTEADLI+LM+KHGIGTDATHAEHIETIK+R YVGL D RF+PG LG+ L +GYD+MG+EMSKP LR+ LEADLK ICEG K VVL++QI YK VF AV H K+DEA +Y E E + P + +TI+ KC + V+K N G C P C W + L S +P L + C + + + S R + G N+ + ++ +N+ +S + Q PA +E N++ CNCG A+ TV KEGPN+GR F+ C + C FF W D EV +S P +F GN +N +P+ TV G G + + S RE GS+ K +R C +CH+ GHTR CP NR
Sbjct: 25 KKTLEKEVKQCQSLLIWTDCDREGENIGFEIIHVCKAVKPNLRVFRARFSEITANAVKTACQHLTEPDQRVSDAVEVRQELDLRIGAAFTRFQTLRLQKIFPEVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPETFHKIK-VTHEHEDGVVDFSWKRHRLFNHTACLVLYQMCMEDPVATVVEVASKPKSKWRPQPLDTVELEKLASRKLKINAKETMKIAEKLYTQGYISYPRTETNIFPKDLNLTTLVQQQTHDQQWGAFAQRILDRGGPTPRNGKKSDQAHPPIHPTKYTCNLQGNEKRLYEFIVRHFLACCSEDALGQETTVEIDIAQERFVAHGLMILARNYLDVYIYDKWSDKVIPIYEKDSCFQPTTIEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAEHIETIKSRMYVGLTSDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICEGKKDKHVVLRQQIQKYKQVFIEAVAHANKLDEALSQYFGEMATAVEQEELY---------PAMPETIR-KCPQ-CNKDMVLKRKKNGGFYISCMGYP-----DCRKAIWFPDSVLEVSKDESVCPVCKPHPVYRLKLKFKRGSVPPTMPLEFVGCVG-GCDETLSQILDLRSSSGPSR------ASQPSGQPTNYLQANQSLNRMSNSQGRSSISPTEQQTRPLEPSARRPAATNENHNTVMCNCGQEALLLTVRKEGPNQGRLFYKC-----NTNNCNFFLWADSHQGTEVASSSRIRTPSHFQGNSTNSGGRQDGFGNHGSAICMCNQPAITRTVQKEGPNKGRQFHTCSKPREQQCGFFQWADENMVPVNSGPVWFRGRGSEAKSKRPRTNSNTDPTTKKVRKCSVCHQPGHTRITCPQNR 888
BLAST of EMLSAG00000003780 vs. nr
Match: gi|1002589351|ref|XP_015673334.1| (PREDICTED: DNA topoisomerase 3-alpha [Protobothrops mucrosquamatus]) HSP 1 Score: 662.529 bits (1708), Expect = 0.000e+0 Identity = 378/791 (47.79%), Postives = 475/791 (60.05%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPS-LAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG-------------------------------------GNEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQ-DNRFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRDSNDEGFF-SMSNESRFTPTLSQTIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDEPPLPSSSSAXI--PSNSSLSNXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPS------TSSFNSNSQPAI-------------------NDENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGNFNGNDSNFRRPSRDSTVPSRGGGGGLKRSGS 755
++TLERE C+ L+IWTD DREGENIGFEI VC V P L+V RA+FSEIT +I++A LT+PD + AV+VRQ+LDLRIGAAFTRFQTLRL K FP LAEQLISYGSCQFPT+GFVVER+KAI+AFV E F+KIK VTH++E V+FSWKR RLF+ A V + +C E+P A V + SKPKSKWRPLPLDTVELEKLASRKL I+AK TM+ AEKLYT G+ISYPRTETNI+PK+LNLS LV++QTQ P WG GNE +LYEFIVRHFLA S+DA G+ETTV IDI+ E+F+ HG IL RNYL VYPYERWSDK I YE F+PT++++V G TSPP LLTEADLISLM++HGIGTDATHAEHIETIK+R YVGL D RF+PG LG+ L +GYD+MG+EMSKP LR+ LE DLK ICEG K VVL+EQI YK VF AV +K+DEA +Y E + + ++ + +M + R P +C D+ ++K N G C P C W + L S + + + G + A +Q G G C N+ + + + V + N PS + + Q + ++ N++ CNCG A+ TV KEGPN+GR+F+ C+ GS C+FF W+D+ S NG S P S++P + G +R GS
Sbjct: 103 KRTLEREVQPCQALVIWTDCDREGENIGFEIIHVCKAVKPNLQVFRARFSEITPRAIQSACENLTQPDPNTNDAVEVRQELDLRIGAAFTRFQTLRLQKIFPEVLAEQLISYGSCQFPTLGFVVERFKAIQAFVQETFYKIK-VTHDHEEGTVDFSWKRHRLFNHTACLVLYQMCMEDPQATVVEVGSKPKSKWRPLPLDTVELEKLASRKLKINAKETMKIAEKLYTQGYISYPRTETNIFPKDLNLSQLVQLQTQDPHWGAFAQRILDQGRPTPRQGAKSDQAHPPIHPTKYAGNLQGNEQRLYEFIVRHFLACCSEDAKGQETTVEIDISYERFVAHGLMILARNYLDVYPYERWSDKVIPLYEKGSCFQPTTVEMVEGETSPPQLLTEADLISLMERHGIGTDATHAEHIETIKSRMYVGLTPDQRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELENDLKLICEGKKDKSVVLREQIQKYKQVFVAAVAKAKKLDEALAQYFGEMTQVAQEDDIYPAMPDPVRKCP------QCNSDM------ILKTRKNGGFYLSCLGYPA-----CKSSVWFPDSVLEVSKDDSVCDVCRPPPVHRLKLKFKRGSLPAVMPLQFVGCIGG-----CDENLRQILDLKYLQGPARVPAQPRNLPSEAPGSLSGVIHGRGQRVLARAPPPAPAHRTPPALANEDENNAVVCNCGQEALLLTVRKEGPNQGRQFYKCNT--GS---CRFFLWSDQQEPS-------NGT-SGLLAPPPSSSLPGQRTAAGPRRVGS 857 HSP 2 Score: 114.005 bits (284), Expect = 2.812e-22 Identity = 72/208 (34.62%), Postives = 96/208 (46.15%), Query Frame = 0
Query: 594 SSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPSTSSFNSNSQP----------------AINDENSLTCNCGNLAIKKTVSKEGPNKGREFWVCSKPFGSNEKCQFFKWTDEVTNSHSNPGNFNGNDSNFRRPSRDSTVPSRGGGGGLKRSGSTTREGGSDKKKRRCGLCHREGHTRNKCPNN 785
+++ CNCG+ A TV+KEG N+GR FY C C FF W+ + N + + S+S P A S C C A+ +TV KEGPNKGR+F CSKP ++C FF+W DE + P F S+F RG G KRS S + K+ R C +CH+ GHT+ CP N
Sbjct: 782 NAVVCNCGQEALLLTVRKEGPNQGRQFYKC-----NTGSCRFFLWSDQQEPSNGTSGLLAPPPSSSLPGQRTAAGPRRVGSNPGASAGRGSPLCRCEQPAVSRTVQKEGPNKGRQFHTCSKP--REQQCGFFEWADE--SVLPAPSTFPS--SHF-----GGEWAKRGPGAKAKRSDSDSSLTAPLKRPRTCSVCHQPGHTKTTCPQN 973 HSP 3 Score: 79.337 bits (194), Expect = 1.478e-11 Identity = 57/153 (37.25%), Postives = 72/153 (47.06%), Query Frame = 0
Query: 527 TIKCKCDLFAAEKTVVKEGPNKGRKFYCCNAPMSGANRCDFFQWVDE------------PP----LPSSSSAXIP----SNSSLS-NXSSITCNCGKVAAYRTVQKEGSNKGRFFYSCPVNMAEGSRCNFFKWAXEVSSFNNNTPSTSSFNSN 658
+ C C A TV KEGPN+GR+FY CN C FF W D+ PP LP +A P SN S S C C + A RTVQKEG NKGR F++C + +C FF+WA E + P+ S+F S+
Sbjct: 783 AVVCNCGQEALLLTVRKEGPNQGRQFYKCN-----TGSCRFFLWSDQQEPSNGTSGLLAPPPSSSLPGQRTAAGPRRVGSNPGASAGRGSPLCRCEQPAVSRTVQKEGPNKGRQFHTC--SKPREQQCGFFEWADE-----SVLPAPSTFPSS 923
BLAST of EMLSAG00000003780 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold98_size375582-snap-gene-2.32 (protein:Tk06130 transcript:maker-scaffold98_size375582-snap-gene-2.32-mRNA-1 annotation:"dna topoisomerase 3-alpha") HSP 1 Score: 580.482 bits (1495), Expect = 0.000e+0 Identity = 294/511 (57.53%), Postives = 349/511 (68.30%), Query Frame = 0
Query: 32 RKTLEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPRLKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPS-LAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIKGVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWGG------------------------------------NEGKLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEILNYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQDNRFVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKIDEACIKYLNESPRD 505
++TLEREA +WLIIWTD DREGENIG+E+ +VC V P L+V RAKFSEIT SI+ AL L +PD + S+AVDVRQ+LDLRIGAAFTRFQT+RL KKFP+ LA++L+SYGSCQFPTMGFVVERYKAIE+FVPEAFWKIK V H VEF W+RVRLFD A Q YHD+C E P+A+V+DC+SKPKSKWRPLP++TVELEKL +RKL +SAKV MQ AEKLYT GFISYPRTETNI+PKELNL LVEMQT+ +W G NE ++YE IVRHFLA VS+DA+GKETTV IDINGEKF+ HG T+++RNYL++Y YE+WSDKEI +YE IE FEPT IDLV G T PP LLTEADLI+LMDKHGIGTD A H + I+ PEVVL+EQI YK+VF++AV+ V KI+E+C KYLN +P+D
Sbjct: 99 KRTLEREAKKAQWLIIWTDCDREGENIGYEVIDVCRAVRPSLRVFRAKFSEITLASIDRALANLGQPDLRVSQAVDVRQELDLRIGAAFTRFQTMRLQKKFPAQLADKLLSYGSCQFPTMGFVVERYKAIESFVPEAFWKIK-VQHRVNGVSVEFHWQRVRLFDHTAAQTYHDVCLEAPLARVDDCRSKPKSKWRPLPMETVELEKLGARKLKLSAKVVMQAAEKLYTQGFISYPRTETNIFPKELNLRPLVEMQTRDQRWSGFAAGVLEHGPNPRQGKKSDQAHPPIHPTKVAANLQGNEARVYELIVRHFLACVSQDALGKETTVTIDINGEKFVAHGLTVVQRNYLEIYIYEKWSDKEIADYEQIESFEPTKIDLVDGQTQPPPLLTEADLIALMDKHGIGTD---ATHADHIETE----------------------------------------------------PEVVLREQIAKYKHVFQMAVRQVDKIEESCAKYLNATPQD 553
BLAST of EMLSAG00000003780 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold1517_size37798-snap-gene-0.13 (protein:Tk07836 transcript:maker-scaffold1517_size37798-snap-gene-0.13-mRNA-1 annotation:"dna topoisomerase 3-beta-1") HSP 1 Score: 315.464 bits (807), Expect = 4.380e-95 Identity = 212/607 (34.93%), Postives = 293/607 (48.27%), Query Frame = 0
Query: 35 LEREASNCEWLIIWTDGDREGENIGFEIREVCLRVAPR-----LKVLRAKFSEITRPSIENALRALTEPDEKQSKAVDVRQQLDLRIGAAFTRFQTLRLAKKFPSLAEQLISYGSCQFPTMGFVVERYKAIEAFVPEAFWKIK-GVTHEYENTKVEFSWKRVRLFDQXATQVYHDICTENPVAKVEDCKSKPKSKWRPLPLDTVELEKLASRKLHISAKVTMQTAEKLYTSGFISYPRTETNIYPKELNLSNLVEMQTQSPQWG----------------GNEG----------------------KLYEFIVRHFLASVSKDAIGKETTVXIDINGEKFIGHGXTILERNYLKVYPYERWSDKEIL-NYEVIEEFEPTSIDLVAGSTSPPNLLTEADLISLMDKHGIGTDATHAEHIETIKNRNYVGLQDNR-FVPGQLGIALCDGYDAMGFEMSKPHLRSSLEADLKAICEGTKIPEVVLQEQINNYKNVFEIAVQHVQKID---EACIKYLNESPRDSNDEG----------------FFSMSNESRFTPT-----LSQTIKCKCDLFAAEKTVVKEGPNKGRKF----YCCNAPMSGANRCDF 567
L EA N E+L++W D D+EGENI FE+ L R +V RAKFS IT I+ A+ L EPDE QSK+VD RQ+LDLRIG AFTRFQT K+ L LISYG CQ PT+GF V+R+ I+ F PE +W I V + W R R FD+ Q++ + A + +K K+K RP+ L+TVEL ++AS L + MQ AEKLY GFISYPRTE+ Y + +L + + Q S WG G++ ++Y+++VRHF+A++S++ T + I E F G ++ + V + SD E L N +E + L+ TSPP+ LTE+DLI+LM+KHGIGTDA+ HI I RNYV + R +P LGI L GY + ++ P +RS +E L I G + VL+ + +K F+ V ++ +D E L S R + G + S +E+ P L Q +KC D F E V GP G+ + YC N P G R D
Sbjct: 126 LASEAKNNEFLVLWLDCDKEGENICFEVIHSVLDSMKRPPGNHRQVHRAKFSSITDKDIKLAMNNLGEPDENQSKSVDARQELDLRIGCAFTRFQTKFFQGKYGDLDSSLISYGPCQTPTLGFCVDRHDIIQTFKPEPYWTIAVKVKLGVSERQFPIDWDRQRCFDKEVAQMFLSDVKTHKYATITSITAKEKAKERPIALNTVELMRMASSGLGMGPHHAMQIAEKLYIQGFISYPRTESTHYSENFDLRDALRQQQNSSDWGPEVKEILSQGVNKPKKGHDAGDHPPITPMRAASRDQFDSDSWRIYDYVVRHFIATLSRNCKYLSTVIAFKIGDESFSLTGKKTIDPGFTAVMSWSAASDDETLPNVNQGDELMIEDVRLLEKQTSPPDYLTESDLITLMEKHGIGTDASIPVHINNICQRNYVTIGSGRKLIPTTLGIVLVHGYLKIDPDLVHPQMRSGVEEQLDLIALGKANYKSVLKHTLEVFKLKFQYFVTNISGMDQLFEVSFSSLANSGRPFSRCGKCRRFMKYIMAKPSRLYCSTCDETLGLPQNGNIKLYQELKCPLDDF--EILYVTAGPG-GKSYIFCPYCYNNPPFGEMRKDM 729 The following BLAST results are available for this feature:
BLAST of EMLSAG00000003780 vs. GO
Analysis Date: 2014-04-02 (Blast vs. GO) Total hits: 25
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BLAST of EMLSAG00000003780 vs. C. finmarchicus
Analysis Date: 2014-05-09 (TblastN vs C. finmarchicus TSA) Total hits: 25
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BLAST of EMLSAG00000003780 vs. L. salmonis peptides
Analysis Date: 2014-05-10 (Blastp vs. self) Total hits: 2
BLAST of EMLSAG00000003780 vs. SwissProt
Analysis Date: 2017-02-10 (Blastp vs. SwissProt) Total hits: 25
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BLAST of EMLSAG00000003780 vs. Select Arthropod Genomes
Analysis Date: 2017-02-20 (Blastp vs. Selected Arthropods) Total hits: 23
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BLAST of EMLSAG00000003780 vs. nr
Analysis Date: 2017-02-20 (Blastp vs. NR (2/2017)) Total hits: 25
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BLAST of EMLSAG00000003780 vs. Tigriopus kingsejongenis genes
Analysis Date: 2018-04-18 (Blastp vs. Tigriopus kingsejongensis proteins) Total hits: 2
Alignments
The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Cross References
External references for this gene
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at LSalAtl2s204:481614..491509+ Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>EMLSAG00000003780-686546 ID=EMLSAG00000003780-686546|Name=EMLSAG00000003780|organism=Lepeophtheirus salmonis|type=gene|length=9896bp|location=Sequence derived from alignment at LSalAtl2s204:481614..491509+ (Lepeophtheirus salmonis)back to top Add to Basket
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