Query:  309 GGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEK-KQTVLGAIIVVKND--KKINVETIRKELNKKVDEY---KRIEGQLLLTKEPL---PRNAMGKLLRSEIQKLFKS 489
            G +VA TE  I    TG+ +GP + GE++ R       GYLN  +   + F++DGW HTGD  +   +G      RI EMIK +G  V P E+E LL   H D+ +VGV  V +        A +V+K D  +++  E   + + K++ EY   K++  + ++  E L   P++A GK+LR  ++   +S
Sbjct:  505 GMIVANTEVKIIHTETGKEVGPEEEGEILARGPQIV-MGYLNNEKATRETFDEDGWLHTGDVGYMDREGFIVITDRIKEMIKVKGIAVSPAEIEDLLLG-HPDVEDVGVTSVADDYAGERPKAYVVLKGDAKRRLGSEEGVQAVGKQLIEYVKAKKVRHKWIVEVEFLEEVPKSASGKILRRVLRDRERS 692          

Query:  309 GGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEK-KQTVLGAIIVVKND--KKINVETIRKELNKKVDEY---KRIEGQLLLTKEPL---PRNAMGKLLRSEIQKLFKS 489
            G +VA TE  I    TG+ +GP + GE++ R       GYLN  +   + F++DGW HTGD  +   +G      RI EMIK +G  V P E+E LL   H D+ +VGV  V +        A +V+K D  +++  E   + + K++ EY   K++  + ++  E L   P++A GK+LR  ++   +S
Sbjct:  505 GMIVANTEVKIIHTETGKEVGPEEEGEILARGPQIV-MGYLNNEKATRETFDEDGWLHTGDVGYMDREGFIVITDRIKEMIKVKGIAVSPAEIEDLLLG-HPDVEDVGVTSVADDYAGERPKAYVVLKGDAKRRLGSEEGVQAVGKQLIEYVKAKKVRHKWIVEVEFLEEVPKSASGKILRRVLRDRERS 692          

Query:   82 KVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDTQAEIVF------------CTNKTFKK-----VKNCGCTIINMDTDIEEMIANGCTSKVIVPKQDVFSLKDVFVILWSSGTTGQPKGVQMT----------VVSFLDSMFATPKVKGNMLLSANFG-----HISGFISSLFWTFHFSTSTFY-----------------------------YISSDDVKHFGVVKLFEV--------------LKKCVPNF-----YGSTESGGGFLVSTNQHSNGGV---VARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEV---GVVPVVEKKQTVLGAIIVVKNDKKINV-ETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLF 487
            KV  +++   E G +K DV  L   N    +           ++S +    +   +  ++ D+Q++++             C N  F K       N    +I  D     ++ N     +I PK D+  L       +SSGTTG+PKGV ++           + F D+      +  + +L  +       H  G   +L  ++  +T   +                              ++S  ++ + V  L  V              LK+ +PN      YG TE      + +    +G V   V  T   ++    G   GP++IGEL   K      GY  + ++  ++ ++ G+  TGD  ++ + GE F   RI E+IK     V P ELE ++   HDD+ +V   GV      ++ V  A +V K  + +   + I K +N+K+  YK I+    +++  + R   GKLLR  ++K F
Sbjct:   54 KVLQISEWFVENGYKKGDVFLLASYNNWRCFAAALGAWRAGLIVSAAASQFTSFEMNYQIEDSQSQVILVDKHTLPVVQEACKNLKFVKQIISISANPPSPVIKFDVLTSRLVRN-LKMPLIDPKNDIVFLP------YSSGTTGKPKGVMISHLNFSMMLESSLRFFDANAKAIGLPPDFVLPYDLHFLPMYHAMGMFRTLLTSYRGTTQIMFTKFDMELMLKNIEKYSIMVLSLVPAIAVRMLNSPLLQKYDVSSLVSVTVGSAPFPESASKKLKQLLPNVNIVQGYGMTELTFATHLQSPGSPDGSVGRLVPGTSMKVKK-EDGTLCGPHEIGELWI-KGPQMMKGYWKKEQQTNELLDEHGFMRTGDIVYFDKNGETFICDRIKELIKVNAKQVAPAELESVILE-HDDVADVCVFGVDDASSGERPV--ACVVSKRGRDMETSKAIMKHINQKLARYKHIKEIEFVSE--IMRTGTGKLLRRAMKKAF 532          

Query:  165 TIINMDTDIEEMIANGCTSKVIVPKQDVFSLKDVFVILWSSGTTGQPKGVQMTVVSFLDSMFATPKVKGNM-------------------LLSANFGHISGF---------------------------------------ISSLFWT-FHFSTSTFYYISSDDVKHFG----VVKLFEVLKKCVP-----NFYGSTESGGGFLVSTNQ------HSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEK-KQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLFKS 489
             I+    D E++   G T   I P  D         I+++SGTTG+PKG   T  + + +MF +   +  M                   L+S  F H +G                                        + ++ W          Y +SS     +G      +L   +KK  P     N +G TE+     ++  +       S G   A  E  I D + G  +   ++GEL  + A A    Y NR +   + F ++GW  TGD     E+G  +   R  +M+   G +VY IE+E  L   H  +++  VV +  K     +GA++ +K  K  +   +R  +  ++  +K +  ++    EPLPRNA GK+L++E+++ FK+
Sbjct:  194 AIVGHPNDWEDLPDAGPTGVEIGPDDDA-------TIMYTSGTTGKPKGALATHRAVITNMFNSSACQARMFLRKGEPVPAPDPDAMRATLISIPFFHATGSFAILIPSALRGDKVVAMYKWDAGEALPIIEGEKISAVGGVPAIAWQILEHPDRDKYNLSSIQAISYGGAPSAPELVSTIKKRFPEAAPGNGWGMTETCATATLNIGEDYVNRPSSAGAPPAAVELKICDPD-GNDMPAGEVGELWCKSA-ANCRQYWNRPDATAETF-RNGWVVTGDLARIDEEGFLYLVDRAKDMLIRGGENVYCIEVESALYD-HPAVMDAAVVGIAHKILGEEVGAVVQLKPGKAASEAELRAHVAGQLAAFK-VPVEIQFQDEPLPRNANGKILKAELRQRFKA 581          

Query:  331 NKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLR 480
            N+ GE+  R       GYL R E        DGW HTGD  +  E G  F   R+ E+IK +G  V P ELE LL + H  I +  V+ + + K   L    VV+ D  +  + ++  +  KV  YK++EG +   +E +P++A GK+LR
Sbjct:  388 NQRGEICVR-GPTIMLGYLGRPEATASTV-IDGWLHTGDIGYLNEDGNLFIVDRLKELIKVKGLQVPPAELEDLLLS-HPKIRDCAVIGIPDAKAGELPKAFVVRADNTLTEQEVKDFVKPKVSPYKQLEGGVEFIEE-IPKSAAGKILR 533          

Query:   14 VLTTKSDDNRTLQAEYNQNLAECFLDKITKYLEVNEDKELLVNCGKRFFPDETVSDGPVAHTLKDFLHKVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGXXXXXXXXXXHDTLMTELNDTQAEIVFCT----------NKTFK---KVKNCGCTIINMDTDIEEMIANGCTS--------------KVIVPKQDVFSLKDVFVILWSSGTTGQPKGVQMTVVSFLDSMFATPKVK--------------GNMLLSANFGHISGFISSLFWTFHFS-----------TSTFYY--------ISSDDVKHFGVVKLFEV--------------LKKCVPN------FYGSTESGGGFLVSTNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQ--TVLGAIIVVKNDKKINV---ETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLFKSS 490
            +L +K +D      E++       LD + + L    +++ +V+C         V    V  +  + L +   +A  L + G      +H    +  D Y PVF   L  GV+S++   +S D +  +L DT+A IV CT          NK  K   +VK+    I+ +D +  + +  GCTS                 +PK D    ++V VI W+SGT+G+PKGV M    +L  M    K+               G  LL  + G ++ F   L     F+              FY         ++S + K + +  +F +              LK   PN      FYGSTE  G    S +    G ++   + YIRD  TG+ LGPN+ GE+M  K     TGYLNR EE ++ ++++G+ H GD  +Y E+G+ F+  RI E+IK       P E+E +L+ +   + E  V     K     ++ A IV+    K+ V   E I   +   +   K I G ++   + +P N  GK LR E++  + ++
Sbjct:  158 ILHSKQEDE---AQEFSNRYVLRLLDMVRQELRETGERDWMVDC---------VDQASVRLSHIEGLSR--RVASGLAKLGFGPGQTLHTAYNSCLDFYWPVFGAWLNAGVVSVADPLLSVDAVKGQLEDTKASIVVCTADAAIKYVEANKKIKETLRVKH----ILVIDKEPWQDLPQGCTSFRSLYNDDGSKCPPASSLPKHDN---EEVAVIHWTSGTSGKPKGV-MHTQRYLHRMLKPSKLPQRSISLSSNIMFHAGAFLLPFDGGIMNRFTCCLIKEEDFTGPKALEAISNYKPAFYMAGTNHVLALASQEAKEYDLSSIFCIMPAGGAVSAGTAANLKTLFPNLAMVYMFYGSTEVSG-ISGSMDVTCLGTLLPGVQVYIRDRETGEKLGPNQAGEIMV-KTKTMMTGYLNRYEETQEFYDEEGFAHMGDLGYYDEEGKLFYKERIKELIKVSNYWFGPGEVENVLEEI-PCVAEAAVWGTYNKHSGDDLVNAAIVLTTGPKLEVITREDIVHHVANNLQIQKHITGNIIFL-DSIPHNPQGKKLRRELKTKYSTN 1765          

Query:   85 ALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGXXXXXXXXXXHDTLMTELNDTQAEIVFCTNKTFKKVKNCGCTIINMDTDIEEMIANGCTSKVIV-----PKQDV-------FSLKDVFVILWSSGTTGQPKGVQM-TVVSFLDSMFATPKVKGNMLLSANFGHISGFI-----------SSLFWTFHFSTSTFYYISSDDVKHFGVVKLFEVLK-------------------------------------------KCVPNFYGSTESGGGFLVSTNQHSN--GGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGV--VPVVEKKQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEI 483
             LA      G+ K +VV +++ N  D Y+PVFA  LC   +S+S   +SH TL  ++  T + ++  + +  +           M+ DI  +  N    + I      P +D        ++  D+  I WSSGTTG+PKG+       F D MF     +   LL+    H+ GF            S +F     S S   +  +D      +V+ F + K                                           K + N+YG TE G   ++S +   +  G  V  TE  I D  TG+     + GE+  RK     + Y+N       +++ DGW HTGD  +  + G+  F  RI  +IK  G HV P+E+E LL   +  + E  V  VP    ++ V  A+ + + D  +N++ +++ +N ++DE+K+I G + +  + +PRNA GK+L+ ++
Sbjct:  225 GLATEWRRMGMMKEEVVTIMMDNCTDFYIPVFAAWLCGAGVSLSDPDLSHRTLGRQVKLTGSRVLVASARVVETALEMQRGEAGMEIDIYTIGNNELEVRNIEDFYANPNRDFKEDHKIEYADDDIAAIFWSSGTTGEPKGIPYHQKYIFSDEMFTHTDERSPSLLTTCMFHVVGFFKVLNFLIVNKQSCIFLDPSCSASDMLHAINDYSPVRAIVQPFHIPKLLSSQHRDNKKPMSLESLEDLIPVGAPLPTKYEPILFEKFKGLKTIKNYYGMTELG---VISHSLSLDCIGKPVHGTEVKIIDPETGEVQLTGQAGEICVRKEEKIKS-YIN---SEVSIWDSDGWAHTGDLAYINDAGDMVFVDRIKGLIKVGGKHVQPVEIENLL-TRYPFVKEAAVFGVPDPLHQELVTAAVALTEEDAIVNLKELQENVNAELDEHKKIRGGIFVVDD-IPRNAHGKVLKQKL 1607          

Query:   67 VSDGPVAHT--LKDFLHKVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGXXXXXXXXXXHDTLMTELNDTQAEIVFCTNKTFKKVKN--CGCTIINMDTDIEEMIANGCTSKVIV--------PKQDVFSLKDVFVILWSSGTTGQPKGVQMTVVSFLDSMFATPKVKGNMLLSANFG--------HISGFISSLFWTFHFSTSTFYYISSDDV------------KHFGVV------------------------------KLFEV----LKKCVP-----NFYGSTESGGGFLVSTNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVLG----AIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLF 487
            ++DG    T  L +       LAK L  KGL+  +VV ++  +R +  +   A  LC  V +    + S  TL   L+    +I+  ++    K++N      I+    D  + IA    SK           P  D  S  D+ ++LWSSG+TG PKG+++   + + +     +   + ++   F         H SGFI SL         +  ++ +D V            K  G++                              ++ EV    LK+ +P     N YGS E+GG    S  Q + G +   T   I ++ TGQ LGP +IG++   K +    GY+N   +N+ +F+ +G+   GD  ++ E G  +F  R+ ++I+     VYP+  E +L + H D+++ GV  + +    VLG    A++  + +  +  E +R   N++++E+ ++  + +     +P N +GK +R E QK++
Sbjct:  180 LTDGHTGKTILLSEMERSARGLAKVLQGKGLKPGEVVTMVDRSRVETPVLALAVWLCGAVFNTMDPNPSRSTLEGNLSSFPPKILLTSSDYLNKLENFCVDNNILIWLYDQADSIAELVPSKEECKEDGSEHFPTSDDPS--DLALVLWSSGSTGSPKGIKLPFSALIGTCLRQREAPISTIIDPEFKFLVCTRMFHFSGFIISLCAAADPGPYSVVFLQNDRVTMSLLEHSILTEKPAGLLISYHHTIRMSDQQLRWEEMKDLKVIIPAGARVGEVIESKLKEKLPWVVLSNVYGSIETGGSVAGSVTQANVGLLYPNTWVKIENMETGQKLGPGQIGQICV-KNDKMLIGYIN--ADNDGIFDSEGFFRMGDVGYFDETGMLYFCDRLKDLIRVGDHDVYPVTAEDVLDS-HPDVLQSGVFGLPDP---VLGEVCVALVAARGEGGLGCEEVRAWANRRLEEWSQV--REVREVSTIPVNNIGKKVRKEFQKVW 1634          

Query:   67 VSDGPVAHT--LKDFLHKVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGXXXXXXXXXXHDTLMTELNDTQAEIVFCTNKTFKKVKN--CGCTIINMDTDIEEMIANGCTSKVIV--------PKQDVFSLKDVFVILWSSGTTGQPKGVQMTVVSFLDSMFATPKVKGNMLLSANFG--------HISGFISSLFWTFHFSTSTFYYISSDDV------------KHFGVV------------------------------KLFEV----LKKCVP-----NFYGSTESGGGFLVSTNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVLG----AIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLF 487
            ++DG    T  L +       LAK L  KGL+  +VV ++  +R +  +   A  LC  V +    + S  TL   L+    +I+  ++    K++N      I+    D  + IA    SK           P  D  S  D+ ++LWSSG+TG PKG+++   + + +     +   + ++   F         H SGFI SL         +  ++ +D V            K  G++                              ++ EV    LK+ +P     N YGS E+GG    S  Q + G +   T   I ++ TGQ LGP +IG++   K +    GY+N   +N+ +F+ +G+   GD  ++ E G  +F  R+ ++I+     VYP+  E +L + H D+++ GV  + +    VLG    A++  + +  +  E +R   N++++E+ ++  + +     +P N +GK +R E QK++
Sbjct:  243 LTDGHTGKTILLSEMERSARGLAKVLQGKGLKPGEVVTMVDRSRVETPVLALAVWLCGAVFNTMDPNPSRSTLEGNLSSFPPKILLTSSDYLNKLENFCVDNNILIWLYDQADSIAELVPSKEECKEDGSEHFPTSDDPS--DLALVLWSSGSTGSPKGIKLPFSALIGTCLRQREAPISTIIDPEFKFLVCTRMFHFSGFIISLCAAADPGPYSVVFLQNDRVTMSLLEHSILTEKPAGLLISYHHTIRMSDQQLRWEEMKDLKVIIPAGARVGEVIESKLKEKLPWVVLSNVYGSIETGGSVAGSVTQANVGLLYPNTWVKIENMETGQKLGPGQIGQICV-KNDKMLIGYIN--ADNDGIFDSEGFFRMGDVGYFDETGMLYFCDRLKDLIRVGDHDVYPVTAEDVLDS-HPDVLQSGVFGLPDP---VLGEVCVALVAARGEGGLGCEEVRAWANRRLEEWSQV--REVREVSTIPVNNIGKKVRKEFQKVW 1697          

Query:  286 VPNFYGSTESGGGFLVSTNQHSNGGVVARTETY-IRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKK-QTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKL 486
            V N   ++E      VS NQ + GG+ +  +     +  TG+ +GP  +GE   + + +   GYLN  EEN+  F KDG+ + GDF HY E G  +F  R  ++IK + +H+YP ELE L+   H D+ +V V    E     ++ A++V+ N  K+  E I +++   VD+ +++ G + +  + +PRN  GK+LR  +  L
Sbjct:  253 VGNLLATSEVMTPVAVSFNQKNLGGLFSTVDALKFVNPETGEAVGPYAVGEFAVKVSFSVMLGYLNHEEENDHFFGKDGFLYLGDFGHYDENGVIYFDGRKKDLIKYKNTHLYPRELEDLIMK-HPDVEDVAVFGNPEPSVHELVTAVVVLANGSKVMAEEIIRQVEDNVDDSRKLRGGVFVV-DIIPRNPQGKILRRYLPNL 855          

Query:  286 VPNFYGSTESGGGFLVSTNQHSNGGVVARTETY-IRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKK-QTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKL 486
            V N    +E      VS +Q   GG+ +  E     D  TG+ +GPN  GE   + + +   GYLN  EEN+  F KDG+ + GDF HY + G  ++  R  ++IK + SH+YP E+E  +   H ++ +V V    E   Q ++ A++VV     I  E I  ++ + VD++K++ G +    + +PRN  GK+LR  + KL
Sbjct:  158 VGNVLAQSEILTAVAVSFHQKHLGGLYSAMEALKFVDPETGEAVGPNTEGEFAVKISYSMMLGYLNHKEENDHFFGKDGFFYLGDFGHYDDNGVIYYDGRKKDLIKYKNSHLYPKEIEDFIMK-HPNVEDVAVFGKPEPSVQELVTAVVVVAKGSTITGEEIMTQVEENVDDHKKLRGGVYFV-DKIPRNPQGKILRRNLLKL 760          

Query:  286 VPNFYGSTESGGGFLVSTNQHSNGGVVARTETY-IRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKK-QTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKL 486
            V N    +E      VS +Q   GG+ +  E     D  TG+ +GPN  GE   + + +   GYLN  EEN+  F KDG+ + GDF HY + G  ++  R  ++IK + SH+YP E+E  +   H ++ +V V    E   Q ++ A++VV     I  E I  ++ + VD++K++ G +    + +PRN  GK+LR  + KL
Sbjct:  158 VGNVLAQSEILTAVAVSFHQKHLGGLYSAMEALKFVDPETGEAVGPNTEGEFAVKISYSMMLGYLNHKEENDHFFGKDGFFYLGDFGHYDDNGVIYYDGRKKDLIKYKNSHLYPKEIEDFIMK-HPNVEDVAVFGKPEPSVQELVTAVVVVAKGSTITGEEIMTQVEENVDDHKKLRGGVYFV-DKIPRNPQGKILRRNLLKL 760          

Query:  290 YGSTESGGGFLVSTNQHSNGGV--------VARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPV-VEKKQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLFKSSL 491
            +GSTE  GG   S    + GG+        +      IRD+ T +  GP + GEL+ +  +    GY+N  + N++ F+KDGW  TGD  +Y + G  F   R+ E+IK +G  V P ELE +L+++ + +I+VGV+ +  E++  V  A IV K  + +  E I + +  +V  +K++ G +    E +P++A GK+LR ++Q  +K SL
Sbjct: 1311 WGSTEVAGG--ASGISRACGGIKQGSVNQLLPNLRLQIRDIYTDEPKGPEETGELVLKGPHCM-LGYINNKKANDETFDKDGWMRTGDIGYYDKDGFLFISDRMKELIKVKGLQVAPAELEDVLRSL-EGVIDVGVIGIESEREGQVPRAYIVRK--EGLTEEKIHEYMKVQVSAHKQLVGGIEFI-EAIPKSAAGKILRKDLQVKYKESL 1922          

Query:   86 LAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGXXXXXXXXXXHDTLMTELNDTQAEIVFCTNKTFKKVKNCGCTIINMDTDIEEMIANGCT-------------SKVIVPKQ-DVFSLKDVFVILWSSGTTGQPKGVQMT 217
            ++++L   GL+K DVV L++ N  +  L V   +     ++    + +   +  +L  +Q +++F  +    KV+       N+   +   + NG +             S   +P+Q  V   KD+ ++ +SSGTTG PKGV ++
Sbjct:  480 VSRALRSLGLKKGDVVGLLLPNCLEYPLLVQGCLHSGLALTPMNPAYTAPEISRQLAASQTKVLFTHSSILDKVQETKKLYPNITATV---VINGVSKDGDLSWDDFINISSGPIPEQIPVDVKKDIAILPFSSGTTGVPKGVMLS 908          

Query:  303 TNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKL 486
              + S G +++     + DL++ + LGPN  GEL F K      GY    E  E+ FE DGW  TGD  +Y E+G  +   RI +MIK +G  V P ELE +++ +   + +V V+ + ++K   +    +V+  + +  E I K L  K+ +YK++ G ++  +E LP++  GK+LR E++ +
Sbjct:  144 AKRASVGKILSNISAKVVDLDSKKALGPNMPGEL-FIKGPHVMAGYFKNKEATEESFE-DGWFRTGDVVYYDEEGYVYIVDRIKDMIKVKGYQVAPTELEDVIRTV-PGVKDVAVIGISDEKAGEVPKAFIVRASEDVKEEHIHKFLEDKLAKYKKLSGGIVFLEE-LPKSPTGKVLRKELRNM 683          

Query:  256 HFSTSTFYYISSDDVKHFGVVKLFEVLKKCVPN------FYGSTESGG---------GFLVSTNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQ-KLFKSSLA 492
            H S+  F    +     FG   +   + KC PN       +G TES           GFL        G  V  T   + DL TG+ L P + GEL          GY +R++   K   KDGW HTGD   Y E G++    R+ E+IK +G  V P ELE L++  HD +++V V  V +++   L    V++ ++K+    I K +   V  +K++ G +++  + LP+N  GK+LR E++ ++FK S  
Sbjct: 1160 HLSSVKFV---TGGAAPFGPTMISNFMAKCAPNEIKFQEGFGMTESSPVTHVQPKKDGFL-----GGCGFPVPNTMAKVIDLETGELLPPGEDGELCVSGPQVM-LGY-HRNKRATKNTVKDGWLHTGDVARYREDGQYVIVDRLKELIKVKGFQVAPSELEDLIR-QHDGVVDVAVTGVPDERAGELPRAYVIRKNRKVQEMDIIKFVAAHVAPHKKLGGVMMV--DSLPKNQTGKVLRRELKAQVFKGSFG 1879          

Query:   86 LAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGXXXXXXXXXXHDTLMTELNDTQAEIVFCTNKTFKKVKNCGCTIINMDTDIEEMIANG-------CTSKVI-----------VPKQDVFSLKDVFVILWSSGTTGQPKGVQMT 217
               SL   G +K DV+ +I+ N  +  +     +     ++    +   + +  +L+++ A+ V       +  K     +    T IEE+I  G       C S +            +P ++V   +DV V+ +SSGTTG  KGV +T
Sbjct:  419 FGSSLRRLGAKKGDVIAMILPNIPEFPVAFLGCVGAGLTVTTLNPTYRAEEIARQLDNSGAKYVLTIGLFLQVTKQAASDLTA--TKIEEIIVLGMEETPEDCKSFMSMMITDDGSMYKIPGEEVNPHEDVAVMPYSSGTTGPAKGVCLT 862          

Query:    1 MGNIQHSKISEDYVLTTKSDDNRTLQAEYNQNLAECFLDKITKYLEVNEDKELLVNCGKRFFPDETVSDGPVAHTLKDFLHKVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDTQAEIVFCTNKTFKKVKNCGCTIINMDTDIEEMIANGCTSKVIVPKQDVFSLKDVFVILWSSGTTGQPKGVQMTVVSFLDSMFATPKVKGNMLLSANFGHISGFISSLFWTFHFSTSTFYYISSDDVKHFGVVKLFEVLKKCVPNFYGSTESGGGFLVSTNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLFKSSLA 492
            MGNIQHSKISEDYVLTTKSDDNRTLQAEYNQNLAECFLDKITKYLEVNEDKELLVNCGKRFFPDETVSDGPVAHTLKDFLHKVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDTQAEIVFCTNKTFKKVKNCGCTIINMDTDIEEMIANGCTSKVIVPKQDVFSLKDVFVILWSSGTTGQPKGVQMTVVSFLDSMFATPKVKGNMLLSANFGHISGFISSLFWTFHFSTSTFYYISSDDVKHFGVVKLFEVLKKCVPNFYGSTESGGGFLVSTNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLFKSSLA
Sbjct:    1 MGNIQHSKISEDYVLTTKSDDNRTLQAEYNQNLAECFLDKITKYLEVNEDKELLVNCGKRFFPDETVSDGPVAHTLKDFLHKVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDTQAEIVFCTNKTFKKVKNCGCTIINMDTDIEEMIANGCTSKVIVPKQDVFSLKDVFVILWSSGTTGQPKGVQMTVVSFLDSMFATPKVKGNMLLSANFGHISGFISSLFWTFHFSTSTFYYISSDDVKHFGVVKLFEVLKKCVPNFYGSTESGGGFLVSTNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLFKSSLA 492          

Query:    1 MGNIQHSKISEDYVLTTKSDDNRTLQAEYNQNLAECFLDKITKYLEVNEDKELLVNCGKRFFPDETVSDGPVAHTLKDFLHKVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDTQAEIVFCTNKTFKKVKNCGCTIINMDTDIEEMIANGCTSKVIVPKQDVFSLKDVFVILWSSGTTGQPKGVQMTVVSFLDSMFATPKVKGNMLLSANFGHISGFISSLFW-------TFHF----------------------------STSTFYYISS-------------DDVKHF-------------GVVKLFEVLKKCVPNFYGSTESGGGFLVSTNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKL 486
            MGN+Q SKI+E+ +LT+++D + ++  EYNQN+   F+D + KY+  N +KE LVNCGK++FP ET S+GP + ++ DF+ KVP  AK LYE GLRK DVVH+IIGNR D+Y+PV AT+LCQGV+SISVD+IS +TL++E+ +TQA+ V CTN+T+ KVK+    IIN+DT +  ++    +++  +P+Q  F L+ + VILW+SGTTG+PKG+Q+ +VS  + +F +PK  GNML++ NF H+SGF  S FW       TFHF                            S S   YI+              D+VK+               + KLF  L+  VPN Y  TESGG  L+S +Q SNGGVV   E YIRD+++G+ LGPN  GEL++R  +  + GYLNR +E +K F  DGW  +GD FHY + GE F+  RI EM+K  GSHVYPIE+E ++++M+ +IIE G+    EK QT+LG I+V+K   +I+ E IR+ +N ++D+YK +E  ++LT EPLPRN  GKLLR++I KL
Sbjct:    1 MGNLQSSKINENKILTSQNDFDDSVVLEYNQNITSYFIDSMKKYMTKNSNKEFLVNCGKKYFPGETTSEGPESVSILDFIEKVPKFAKYLYENGLRKGDVVHIIIGNRGDVYIPVHATLLCQGVVSISVDNISTETLLSEVQETQAKFVICTNRTYYKVKDLSSIIINLDTQLHAILEIDMSTQTQIPEQIEFDLQTLAVILWTSGTTGKPKGIQLNMVSLWNLLFLSPKTDGNMLITCNFAHVSGFNYSCFWSINFDVCTFHFISPEDVTSLGVEKIIFTLSQIPFTTIVVSASHIVYIAEKIVNDQIEYSSNFDEVKNICPAGAHTYPGISDDLRKLFRNLEN-VPNLYAMTESGGLILISKDQRSNGGVVGNMEVYIRDIHSGERLGPNTSGELIYRNPDKPTLGYLNRPDETKKFFLDDGWCCSGDMFHYNDHGELFYEGRIKEMLKSNGSHVYPIEIETIIQSMNSNIIEAGLFSKTEKIQTILGGIVVIKKGYRIDPEEIRQFVNDRIDDYKHLE-IIILTNEPLPRNPNGKLLRNDINKL 545          

Query:  307 SNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMH--DDIIEVGVVPVVEKKQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQ-KLFKSSLA 492
            S G ++  T   I D++TG+ LGP + GEL          GY    +  +K+ + +GW HTGD  +Y + G+F+   R+ E+IK +G  V P ELE L++     DD+  VG   V +++   L    VV+ ++ +  + I   + +KV  +K++ G  ++  + LP+N  GK+LR E++ ++FK S  
Sbjct:  399 SCGNLIPNTIGKIIDIDTGKVLGPGENGELCVSGPQIMQ-GYYKNKKATDKIIQ-NGWXHTGDIAYYNQDGQFYIVDRLKELIKVKGLQVAPSELEDLIRKYPGVDDVAXVG---VPDERNGELPRAYVVRKNRSVMEQGIIDFVTEKVAPHKKL-GAGVMFVDTLPKNQTGKILRRELKAQVFKGSFG 581          

Query:  290 YGSTESGGGFLVSTNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKK--QTVLGAIIVVKNDKKINVETI--RKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLFKSS 490
            YGSTE+    L  ++QH  G +  + +  I + N G+ LGPN +G+++ +        Y+   E N     +DG+ + GD  +Y   G+ FF  R  +++K    HVYP E+E  + +    + ++GV    +K   + + G I++   +K ++++ +  R     K   YK ++G + +T   +PRNA GK+ R  +  LF ++
Sbjct:  359 YGSTETLSISLGISDQHL-GRLFPKYQLRILNPN-GEPLGPNSVGDIVVKPGYGMRR-YIGDHEYN---ITQDGFFYMGDVGYYDSAGKIFFKCRSKDLVKVHNHHVYPQEIESFISSKCSFVKDIGVFGQKDKNGIERLSGVIVLHHIEKGLSLQNVLERTFEAYKFPRYKWLQGGVRVTSA-IPRNANGKIFRGRLPLLFNNA 556          

Query:  329 GPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQ-TVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRS 481
            GP++ GE+   K+     GYLN+ E +   F+ D + HTGD  +Y  QG  +F  +IN +I+     V P  LE  L    ++I++  VV +  K+   V  A +V+K   +   E +   +  ++ +++RI G L   +  +PR+   K+LRS
Sbjct:  432 GPDQQGEICV-KSPQCMLGYLNKEESSA--FDNDQYFHTGDLGYYDNQGIVYFVEKINNLIQFWMYEVAPSILESRLLG-SNNIVDAAVVGIPNKENGQVPRAFVVLKPGFEETEENLTNLMESRLQDHERIRGGLYFVQN-IPRDENWKVLRS 580          

Query:  198 VFVILWSSGTTGQPKGVQMTVVSFLDSMFATPKVKGNML----------LSANFGHISGFISSLFWTFHF--------STSTFYYISSDDVKH-FGVVKLFEVL---KKCVPNFYGSTESGGGFLVSTNQHS-------NGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPV 420
            +F I ++SGTTG PK V ++    +++   T    G  L          L   FG ++G + SL +             T+    I ++   + FG   ++  +   +K + N YG+TE+G    ++  + S        G  +   E  I D N G+ L  N  GEL  R       GY    + ++K+   D + H+GD    TE+G      R+++M+   G ++YP E+E  L   H  I+EV +V V
Sbjct:    1 MFNIQFTSGTTGLPKAVALSHFCVINNALLTGNRIGFDLKYHXINLWVPLFHTFGCVTGTLISLCYGSKLVLPSDGFDPTACLNCIPAEKCTYLFGTPTMYIAVLEAQKKLRNIYGATETGPVSFIACPKDSFEVRINTVGPPLGHIEAKIVDQN-GKILPVNTPGELWVRTPGLMH-GYYKDQKSSKKVIGPDRYYHSGDLGMITEKGYCKIIGRLDDMVIRGGENIYPKEIEDFL-LKHPSIVEVYIVGV 249          

Query:  284 KCVPNFYGSTESGGGFLVSTNQHS-------NGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPV 420
            K + N YG+TE+G    V + + S        G  +   E  I D N G+ L  N  GEL  R       GY    + ++K    D + H+GD    TE+G      R+++M+   G ++YP E+E  L   H +I+EV ++ V
Sbjct:  708 KSLMNIYGATETGPATFVPSPEDSFEVRINTVGPPLGHVEAKIVDQN-GKILPVNTPGELWVRTPGLMH-GYYKDQKSSQKAIGPDRYYHSGDLAMITEKGYGKIIGRLDDMVNRGGENIYPKEIEDFL-LKHPNIVEVYIIGV 848          

Query:  284 KCVPNFYGSTESGGGFLVSTNQHS-------NGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPV 420
            K + N YG+TE+G    ++  + S        G  +   E  I D N G+ L  N  GEL  R       GY    + ++K+   D + H+GD    TE+G      R+++M+   G ++YP E+E +L   H  I+EV +V V
Sbjct:  337 KSLMNIYGATETGPVSFIACPKDSFEVRINTVGPPLGHIEAKIVDQN-GKILPVNTPGELWVRTPGLMH-GYYKDQKSSKKVIGPDRYYHSGDLGMITEKGYCKIIGRLDDMVIRGGENIYPKEIEDVL-LKHPSIVEVYIVGV 477          

Query:   75 TLKDFLHKVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDTQAEIVFCTNKTFKKVKNCGCTIINMDTDIEEMIANGCTSKVI-----------VPKQDVFSLK--DVFVILWSSGTTGQPKGVQMTVVSFLDS--------------------------MFATPKV------KGNMLLS-ANF------GHISGFISSLFWTF--------------HFSTSTFYYISSDDVKHFGVVKLFEVLKKCVPNF-----YGSTESGG------GFLVSTNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVV-EKKQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLFKSSL 491
            T       V  LA   +  G+RK+DVV +   N     L   A     GV + +    + + +  ++ D+  +I+   N+ F K+K     ++ + +     I  G  SK++           V +     +K  D   +L+SSGTTG  KGV++T  +F+ +                          +F    +      +GN L+S A F       +I  F  +  W                 F  S+  YI S      G   L E   + +PN      YG TE+ G        L   N  S G +    E  I  + TG+   PN+ GE+  R  N    GYLN  +  ++  +K  W HTGD  ++ E G  +   RI E+IK +G  V P ELEGLL + H DI++  V+P   E+   V  A +V   +  I  + I+K + K+V  YKR+     ++   +P++A GK+LR E+ +  +S +
Sbjct:   56 TFSQLKSAVARLAHGFHRLGIRKNDVVLIFAPNSYQFPLCFLAVTAIGGVFTTANPLYTVNEVSKQIKDSNPKIIISVNQLFDKIKGFDLPVVLLGSKDTVEIPPGSNSKILSFDNVMELSEPVSEYPFVEIKQSDTAALLYSSGTTGTSKGVELTHGNFIAASLMVTMDQDLMGEYHGVFLCFLPMFHVFGLAVITYSQLQRGNALVSMARFELELVLKNIEKFRVTHLWVVPPVFLALSKQSIVKKFDLSSLKYIGSG-AAPLGK-DLMEECGRNIPNVLLMQGYGMTETCGIVSVEDPRLGKRNSGSAGMLAPGVEAQIVSVETGKSQPPNQQGEIWVRGPNMMK-GYLNNPQATKETIDKKSWVHTGDLGYFNEDGNLYVVDRIKELIKYKGFQVAPAELEGLLVS-HPDILDAVVIPFPDEEAGEVPIAFVVRSPNSSITEQDIQKFIAKQVAPYKRLRRVSFISL--VPKSAAGKILRRELVQQVRSKM 544          

Query:   73 AHT-----LKDFLHKVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISV-DSISHDTLMTELNDTQAEIVFCTNKTFKKVKNCGC------TIINMDTDIEEMIANGCTSKVIVPKQDV-----------FSLKD-VFVILWSSGTTGQPKGVQMT---VVS---------FLDSMFATPKVKGNMLLSANFGHIS-------GFISSLFWTFH------------------FSTSTFYYISSDDVKHFGVVKLFEVLKKCVP---------------NF----YGSTESGGGFLVSTNQH----SNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVLGAI-IVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLFK 488
            AHT      ++FL     LA+S  + GL+++D + +   N    +LP+ A+ L  G+I+  V D      L+  L   +  I+FC+  TF+KV N         TII +D + E++    C +  I    D+           F+  D V ++++SSGTTG  KGV +T   +V+         F +++  T  +   +     FG  +       GF  +L  TF                     T   ++  S  V+ + +  L E+     P               NF    YG TE+    L++ +      S G +V      + D  TG+ LGPN+ GEL F K +     Y N  E  + +  KDGW  +GD  +Y   G F+   R+  +IK +G  V P E+EG+L   H  I++ GV  + ++    L A  +VV+  K +N + ++  ++ +V   K + G +    E +P+ + GK+ R  ++++F+
Sbjct:   44 AHTKENVLYEEFLKLSCRLAESFKKYGLKQNDTIAVCSENGLQFFLPLIAS-LYLGIIAAPVSDKYIERELIHSLGIVKPRIIFCSKNTFQKVLNVKSKLKYVETIIILDLN-EDLGGYQCLNNFISQNSDINLDVKKFKPNSFNRDDQVALVMFSSGTTGVSKGVMLTHKNIVARFSHCKDPTFGNAINPTTAILTVIPFHHGFGMTTTLGYFTCGFRVALMHTFEEKLFLQSLQDYKVESTLLVPTLMAFFPKSALVEKYDLSHLKEIASGGAPLSKEIGEMVKKRFKLNFVRQGYGLTETTSAVLITPDTDVRPGSTGKIVPFHAVKVVDPTTGKILGPNETGELYF-KGDMIMKSYYNNEEATKAIINKDGWLRSGDIAYYDNDGHFYIVDRLKSLIKYKGYQVAPAEIEGIL-LQHPYIVDAGVTGIPDEAAGELPAAGVVVQTGKYLNEQIVQNFVSSQVSTAKWLRGGVKFLDE-IPKGSTGKIDRKVLRQMFE 539          

Query:   86 LAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDTQAEIVFCTNKTFKKVKNC---GCTIINMDTDIEEMIANGCT-----SKVIVPKQDVF----SLKDVFVILWSSGTTGQPKGVQMT-------------------------VVSFLDSMFATPKVKGNMLLSANFGH-----------------------ISGFISSLFWTFHFSTSTFYY-ISSDDVKHFGVVKLFEVLKKCV----PNF-----YGSTESGGGFLVS---------TNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQ-TVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLFKSSL 491
            LA  L+  G+++ DVV +++ N  ++ L   A      + + +    +   +  +   + A+++   ++   K+KN    G  I+  D+D    I   C      ++   P+ D      S +DV  + +SSGTTG PKGV +T                         V+  +  MF    +   ML S   G                        ++  +  +      S  T  Y +SS  +   G   L + L+  +    PN      YG TE+G    +S             + G VV   E  I D +TG  L  NK GE+  R  N    GYLN         +KDGW HTGD     +  E F   R+ E+IK +G  V P ELE LL   H +I +V VV + E+    V  A +V   D  I+ + I++ ++K+V  YKRI  ++  T + +P+   GK+LR +++    + L
Sbjct:   76 LAAGLHNLGVKQHDVVMILLPNSPEVVLTFLAASFIGAITTSANPFFTPAEISKQAKASAAKLIVTQSRYVDKIKNLQNDGVLIVTTDSD---AIPENCLRFSELTQSEEPRVDSIPEKISPEDVVALPFSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFNRDDVILCVLPMFHIYALNSIMLCSLRVGATILIMPKFEITLLLEQIQRCKVTVAMVVPPIVLAIAKSPETEKYDLSSVRMVKSGAAPLGKELEDAISAKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKILDPDTGDSLPRNKPGEICIR-GNQIMKGYLNDPLATASTIDKDGWLHTGDVGFIDDDDELFIVDRLKELIKYKGFQVAPAELESLLIG-HPEINDVAVVAMKEEDAGEVPVAFVVRSKDSNISEDEIKQFVSKQVVFYKRI-NKVFFT-DSIPKAPSGKILRKDLRARLANGL 554          

Query:   86 LAKSLYEKGLRKSDVVHLIIGNRADIYLPVFA-TILCQGVISISVDSI-SHDTLMTELNDTQAEIVFCTNKTFKKV---KNCGCTIINMDT----------------DIEEMIANGCTSKVIVPKQDVFSLKDVFVILWSSGTTGQPKGVQMT---VVSFLDSMFATPKVKGNMLLSANFGHISGF------ISSLFWTF-----------------HFST-------------------STFYYISSDDVKHFGVVKLF-EVLKKCVPNF--------YGSTESGGGFLVSTNQH------SNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVLG-AIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLFKSSL 491
            +A  LY  G+RK +VV ++  N   I  P+ + +++  G I  + + I + D +  ++ D++  + F T K   K+    N    ++ MD                  +E MI    +   +  KQ V +  D   +L+SSGTTG  KGV ++   +++ + +  A   ++   + +    HI GF      + +L WT                  H S+                   ++ Y +SS      G   L  EV +K V N+        YG TES        N+       ++G +    E  I D +TG+ LG N+ GEL  R       GY    E      + +GW  TGD  +    G  F   R+ E+IKC G  V P ELE LL A H +I +  V+P+ + K      A IV K    ++   I   + K+V  YK+I     L    +P+N  GK+LR E+ KL  S L
Sbjct:   87 VAGCLYALGVRKGNVVIILSPN--SILFPIVSLSVMSLGAIITTANPINTSDEISKQIGDSRPVLAFTTCKLVSKLAAASNFNLPVVLMDDYHVPSQSYGDRVKLVGRLETMIETEPSESRV--KQRV-NQDDTAALLYSSGTTGTSKGVMLSHRNLIALVQAYRARFGLEQRTICTIPMCHIFGFGGFATGLIALGWTIVVLPKFDMAKLLSAVETHRSSYLSLVPPIVVAMVNGANEINSKYDLSSLHTVVAGGAPLSREVTEKFVENYPKVKILQGYGLTESTAIAASMFNKEETKRYGASGLLAPNVEGKIVDPDTGRVLGVNQTGELWIRSPTVMK-GYFKNKEATASTIDSEGWLKTGDLCYIDGDGFVFVVDRLKELIKCNGYQVAPAELEALLLA-HPEIADAAVIPIPDMKAGQYPMAYIVRKVGSNLSESEIMGFVAKQVSPYKKIRKVTFLAS--IPKNPSGKILRRELTKLTTSKL 565          

Query:   86 LAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDTQAEIVFCTNKTFKKVKNCG------CTIINMD------------TDIEEMIANGCTSKVIVPKQDVFSLKDVFVILWSSGTTGQPKGVQM----TVVSF---LDSMFATPKVKGNMLLSA-NFGHISGFISSLFW---------TFHFSTSTF--------------------YYISSDDVKHFGVVKLFEVLKKCVP-------------------NFYGSTESGGGFLVSTNQHSNGGVVART----ETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVL-GAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLF 487
            LA+++   GL  +  + +   N    ++PV   +     ++ + D  +   L+  +N +Q  +VF + K  +K+ N          II MD            T +   +  G      VP +     K + +I+ SSG+TG PKGV +      V F    D +F    +    +LS   F H  G  ++L +          + F    F                    ++  S  +  + +  L E+     P                     YG TE+    L++       G V +     E  + DL+TG+ LG N+ GEL  R     S GY+N  E    + +KDGW H+GD  ++ E   FF   R+  +IK +G  V P ELE +L   H +I + GV  + +     L  A++V+++ K +  + I   +  +V   K++ G ++   E +P+   GKL   +I+++ 
Sbjct:   63 LAEAMKRYGLNTNHRIVVCSENSLQFFMPVLGALFIGVAVAPANDIYNERELLNSMNISQPTVVFVSKKGLQKILNVQKKLPIIQKIIIMDSKTDYQGFQSMYTFVTSHLPPGFNEYDFVP-ESFDRDKTIALIMNSSGSTGLPKGVALPHRTACVRFSHARDPIFGNQIIPDTAILSVVPFHHGFGMFTTLGYLICGFRVVLMYRFEEELFLRSLQDYKIQSALLVPTLFSFFAKSTLIDKYDLSNLHEIASGGAPLSKEVGEAVAKRFHLPGIRQGYGLTETTSAILITPEGDDKPGAVGKVVPFFEAKVVDLDTGKTLGVNQRGELCVRGPMIMS-GYVNNPEATNALIDKDGWLHSGDIAYWDEDEHFFIVDRLKSLIKYKGYQVAPAELESIL-LQHPNIFDAGVAGLPDDDAGELPAAVVVLEHGKTMTEKEIVDYVASQVTTAKKLRGGVVFVDE-VPKGLTGKLDARKIREIL 539          

Query:   72 VAHTLKDFLHKVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDTQAEIVFCTNK------TFKKVKNCGCTIINMDTDIEEMIANGCTSKVI----VPKQDVFSLKDVFV--------ILWSSGTTGQPKGVQMT----VVSF---LDSMFATPKVKGNMLLSA-NFGHISGFISSLFWTF---------HFSTSTFYYISSDDVKHFGVV---KLFEVLKKC-------------------------------------VPNFYGSTESGGGFLVST----NQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVL-GAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLFKSSLA 492
            V ++  ++L K   L K+L   GL     + L   N  + ++PV A +     ++ + +  +   L+  L  ++  IVF + K      T +K      TI+ +D+ ++      C    I     P     S K V V        I+ SSG+TG PKGVQ+T    V  F    D ++      G  +L+   F H  G  ++L +            F   TF   +  D K   V+    LF +L K                                      V   YG TE+    +++        ++G VV   +  + DL+T + LGPN+ GE+   K      GY+N  E  +++ +++GW HTGD  +Y E+  FF   R+  +IK +G  V P ELE +L   H  I + GV  V +     L GA++V+++ K +  + +   +  +V   KR+ G +    E +P+   GK+    I+++ K  +A
Sbjct:   51 VDYSYAEYLEKSCCLGKALQNYGLVVDGRIALCSENCEEFFIPVIAGLFIGVGVAPTNEIYTLRELVHSLGISKPTIVFSSKKGLDKVITVQKTVTTIKTIVILDSKVDYR-GYQCLDTFIKRNTPPGFQASSFKTVEVDRKEQVALIMNSSGSTGLPKGVQLTHENTVTRFSHARDPIYGNQVSPGTAVLTVVPFHHGFGMFTTLGYLICGFRVVMLTKFDEETFLK-TLQDYKCTSVILVPTLFAILNKSELLNKYDLSNLVEIASGGAPLSKEVGEAVARRFNLPGVRQGYGLTETTSAIIITPEGDDKPGASGKVVPLFKAKVIDLDTKKSLGPNRRGEVCV-KGPMLMKGYVNNPEATKELIDEEGWLHTGDIGYYDEEKHFFIVDRLKSLIKYKGYQVPPAELESVL-LQHPSIFDAGVAGVPDPVAGELPGAVVVLESGKNMTEKEVMDYVASQVSNAKRLRGGVRFVDE-VPKGLTGKIDGRAIREILKKPVA 546          

Query:   86 LAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSIS-HDTLMTELNDTQAEIVFCTNKTFKKVKNCGCTIINMDTDIEEM----------IANGCTSKVIVPKQDVFSLKDVFVILWSSGTTGQPKGVQMT----VVSFLDSMFA-TPKVKGNMLLSA--NFGHISGFISSLFWTFH----------FSTSTFYYISSD-------------------------DVKHFGVVKLFEVLKKCVPNF----------------YGSTE---------SGGGFLVSTNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVV-EKKQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLF 487
             A++L   G+RK  VV + + N A +Y  V   I+  G +   V+  +    +  ++ D++A++V      F KVK+ G  +I +  D E M           A   T   +VP  D     D+  + +SSGTTG  KGV ++    V +   SMFA  P+  G ++      F HI G       T            F   TF     D                         D+    +  +        P+                 YG TE         +G G      + S G ++   E    D +TG+ L  N  GEL  R + +   GY  R EE E+  +  GW HTGD  +    G+ F   RI E+IK +G  V P ELE +L + H  + +  V  V  E+   V  A +V ++  +   E I   + ++V  YKR+  ++L   + +P++  GK+LR +++  F
Sbjct:   74 FARALRSVGVRKGHVVVVALPNLA-VYPVVSLGIMSAGAVFSGVNPRALAAEIKKQVEDSEAKLVVANEVAFDKVKDAGVPVIGVG-DRERMPGAISWDGLLAAADRTGAGVVP-VDAAQQSDLCALPYSSGTTGVSKGVMLSHRNLVSNLCSSMFAVAPETAGQVVTLGLMPFFHIYGITGICCATLRHKGTVVVMDRFDLRTFLRALVDHRVMFAPLVPPVMLAMVKSPVADEFDLSDLALKSVMTAAAPLAPDLLAAFQRKFPGVQVEEAYGLTEHSCITLTHAAGDGHGHVAKKSSVGFILPNLEVKFVDPDTGRSLPANTPGELCVR-SQSVMQGYYKRKEETERTVDGKGWLHTGDVGYIDGDGDVFIVDRIKELIKYKGFQVAPAELEAVLLS-HPSVEDAAVFGVPDEEAGEVPVACVVRRHGAEEGEEEIVAYVAERVASYKRV--RVLHIVDAIPKSVSGKILRRQLRDEF 547          

Query:   73 AHTLKDFLHKVPALAKSLYEK-GLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDTQAEIVFCTNKTFKKVKNCGCTIINMDTDIEEMIANGCTS-------KVIVPKQDVFSLKDVFVILWSSGTTGQPKGVQMTVVSFLDSM--FATPKVKGN---MLLSANFGHISGFISSLFWTFHFSTSTFYYISSDDVKHFGVVKLFEVL--------------------KKC-VPNF------------------------------YGSTESGGGFLVSTNQHSN-----GGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVV-EKKQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEI 483
            A + + FL +V ALA +L  + GLR  DV  ++     D+ +  FA +    V+S +  +++   +   ++ + A + F  + T  K+     T++ +D+     +   C          V+V +Q      +   I +SSGTTG+ K   +   SF+  +  F   + K      LL A   H  GF   LF     +      + +D V   G+  L E                      ++C +P                                YGSTE+GG   + + +  N     G V    E  I D  TG+ L   + GEL  R   A  TGY+  +E N   F  +GW  TGD  +  + G  F   R+ E+IK +   V P ELE +L ++   I++  V+P   E+   +  A++V +   K+    +   + K+V  YK+I   L +  + +P++  GK+LR E+
Sbjct:   78 AVSFQAFLSRVRALAGALRSRVGLRGGDVAFVLAPAGLDVPVLYFALLSIGAVVSPANPALTPAEVSRLVSLSGASVAFAVSSTATKLPAGLTTVVLLDSPHFRSLLMDCGQAQGQEPLPVVVVRQS-----ETAAIQYSSGTTGRVKAAALPHRSFIAMVAGFHALRAKAREVRTLLGAPMFHSMGF---LFVLQGVALGATTVVVTDAVARAGIRGLVEAAERWAVMDMTASPPVVLGMTKQRCRLPALERITCGGAPLPAPAIERFRRRFPHVDLCMGYGSTEAGGISRMISQEECNHIGSAGRVTENVEVKIVDHVTGKPLPAGQQGELWVR-GPAVMTGYVGDNEANATTFNSEGWLKTGDLCYIDQDGFLFVVDRLKELIKYKAYQVPPAELELVLHSL-PQIVDAAVMPYPHEEAGQIPVALVVKQPGSKLTEAEVMYNVAKQVAPYKKIRKVLFV--DSIPKSPSGKILRREL 546          

Query:   86 LAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDT----QAEIVFCTNKTFKKV----KNCGC----TIIN----------MDTDIEEMIANGCTSKVIVPKQDVFSLKDVFVILWSSGTTGQPKGVQMT----VVSFL---DSMFATPKVKGNMLLSA-NFGHISGFISSLFW---------------------------TFHFSTSTFYYI--SSDDVKHFGVVKLFEVLKKCVP-------------------NFYGSTESGGGFLVSTN----QHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVL-GAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLFKSSLA 492
            LA+++   G++  + + L   N  + ++PV A +     I ++V   +    + ELN +    Q  IVF + K   KV    K   C     I++          M+T I++ +  G      VP       + V +++ SSG+TG PKGV++T    V  F    D ++      G  +L+   F H  G  ++L +                           T      T + I   S+ +  F +  L E+     P                     YG TE+   F+++        ++G VV   +  + DL+T + LG N+ GE+   K  +   GY N  E   +  +++GW HTGD  +Y E   FF   R+  +IK +G  V P ELE +L   H +I + GV  V +     L GA++V++  K +  + I   +N +V  +KR+ G +    E +P+   GK+    I+++ K   A
Sbjct:   64 LAEAMKNFGMKPEEHIALCSENCEEFFIPVLAGLY----IGVAVAPTNEIYTLRELNHSLGIAQPTIVFSSRKGLPKVLEVQKTVTCIKKIVILDSKVNFGGHDCMETFIKKHVELGFQPSSFVPIDVKNRKQHVALLMNSSGSTGLPKGVRITHEGAVTRFSHAKDPIYGNQVSPGTAILTVVPFHHGFGMFTTLGYFACGYRVVMLTKFDEELFLRTLQDYKCTSVILVPTLFAILNKSELIDKFDLSNLTEIASGGAPLAKEVGEAVARRFNLPGVRQGYGLTETTSAFIITPEGDDKPGASGKVVPLFKVKVIDLDTKKTLGVNRRGEICV-KGPSLMLGYSNNPEATRETIDEEGWLHTGDIGYYDEDEHFFIVDRLKSLIKYKGYQVPPAELESVL-LQHPNIFDAGVAGVPDPDAGELPGAVVVMEKGKTMTEKEIVDYVNSQVVNHKRLRGGVRFVDE-VPKGLTGKIDAKVIREILKKPQA 546          

Query:   72 VAHTLKDFLHKVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDTQAEIVFCTNK------TFKKVKNCGCTIINMDTDIE----EMIAN-----------GCTSKVIVPKQDVFSLKDVFVILWSSGTTGQPKGVQMT----VVSF---LDSMFATPKVKGNMLLSA-NFGHISGFISSL-FWTFHFS--------------------------TSTFYYI--SSDDVKHFGVVKLFEVLKKCVP-------------------NFYGSTESGGGFLVST----NQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVL-GAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLFKSSLA 492
            V +T  ++L K   L ++L   GL     + L   N  + ++PV A +     ++ + +  +   L+  L  ++  IVF + K      T +K      TI+ +D+ ++    + + N           G + K +    +V   + V +I+ SSG+TG PKGVQ+T    V  F    D ++      G  +L+   F H  G  ++L + T  F                             T + I   S+ +  + +  L E+     P                     YG TE+    +++        ++G VV   +  + DL+T + LGPN+ GE+   K      GY++  E   ++ +++GW HTGD  +Y E+  FF   R+  +IK +G  V P ELE +L   H +I + GV  V +     L GA++V++  K +  + +   +  +V   KR+ G +    E +P+   GK+    I+++ K  +A
Sbjct:   51 VDYTYAEYLEKSCCLGEALKNYGLVVDGRIALCSENCEEFFIPVLAGLFIGVGVAPTNEIYTLRELVHSLGISKPTIVFSSKKGLDKVITVQKTVTAIKTIVILDSKVDYRGYQSMDNFIKKNTPQGFKGSSFKTV----EVNRKEQVALIMNSSGSTGLPKGVQLTHENAVTRFSHARDPIYGNQVSPGTAILTVVPFHHGFGMFTTLGYLTCGFRIVMLTKFDEETFLKTLQDYKCSSVILVPTLFAILNRSELLDKYDLSNLVEIASGGAPLSKEIGEAVARRFNLPGVRQGYGLTETTSAIIITPEGDDKPGASGKVVPLFKAKVIDLDTKKTLGPNRRGEVCV-KGPMLMKGYVDNPEATREIIDEEGWLHTGDIGYYDEEKHFFIVDRLKSLIKYKGYQVPPAELESVL-LQHPNIFDAGVAGVPDPIAGELPGAVVVLEKGKSMTEKEVMDYVASQVSNAKRLRGGVRFVDE-VPKGLTGKIDGKAIREILKKPVA 546          

Query:  290 YGSTESGG----GFLVSTNQHSNGGVVARTETYIRDLN--TGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVV----PVVEKKQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQ 484
            YG TE+      G L S N  S G    RT+  I DLN  T   LGPN+ GEL+ R       GY N  +  ++M  + GW  TGD  HY EQ +F+   R+ E+IK +G  V P ELE LL++ H+ + +  VV    PV  +   V  A +V K   +++ + ++  + +KV  YKR+EG +      +P+NA GK+LR +++
Sbjct:  144 YGLTETAPVVLMGALGSRNYASVGSPCPRTQAKIVDLNDPTNTALGPNQSGELLVRGPQVMK-GYHNNRKATDEMIIEGGWLRTGDIAHYDEQLQFYITDRLKELIKVKGFQVPPAELEELLRS-HEAVADAAVVGMPHPVAGE---VPRAFVVPKAGARVSEDALKAFIAEKVAVYKRLEGGVTFLDS-IPKNASGKILRRQLK 342          

Query:  189 KQDVFSLKDVFVILWSSGTTGQPKGVQMTVVSFLDS--MFATPKVKGNMLLSAN------------FGHISGFISSLFWTF----------HFSTSTF--------------------YYISSDDVKHFGVVKLFEVLKKCVP-------------------NFYGSTESGG----GFLVSTNQHSNGGVVARTETYIRDLN--TGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVV----PVVEKKQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQ 484
            +Q   +  D+  + +SSGTTG PKGV++T ++ + +  M A     G ++L               F HI G   ++              +F   TF                    +    D VK      +  V     P                     YG TE+      G L S N  S G    RT+  I DLN  T   LGPN+ GEL+ R       GY N  +  ++M  + GW  TGD  HY EQ +F+   R+ E+IK +G  V P ELE LL++ H+ + +  VV    PV  +   V  A +V K   +++ + ++  + +KV  YKR+EG +    + +P+NA GK+LR +++
Sbjct:  233 RQHDRTADDIVFLPYSSGTTGMPKGVELTHLNIVSNSEMLAVKAGNGTVVLPTTDTFQDVLPCVLPFFHIYGLTVTMISKLRQGCKLVTLPNFKPDTFLNALAEHKGTVLHLVPPIIIFLGHHDGVKPRHTDSIRNVFSGAAPMGTPDAERFTARAPNAEFIQGYGLTETAPVVLMGALGSRNYASVGSPCPRTQAKIVDLNDPTNTALGPNQSGELLVRGPQVMK-GYHNNRKATDEMIIEGGWLRTGDIAHYDEQLQFYITDRLKELIKVKGFQVPPAELEELLRS-HEAVADAAVVGMPHPVAGE---VPRAFVVPKAGARVSEDALKAFIAEKVAVYKRLEGGVTFL-DSIPKNASGKILRRQLK 595          

Query:   86 LAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTEL----NDTQAEIVFCTNKTFK-------------KVKNCGCTIINMDTDIEEMIANGCTSKVIVPKQDVFSLKDVFVILWSSGTTGQPKGVQMT------------------------VVSFLD--SMFATPKVKGNMLLSANFGHISGFISSLFWT----------FHFSTSTFYYISSDDVKHFGVVKLFEVLKKCVPNF---------------------YGSTESGGGF-LVSTNQHSNGGVVARTETYIRDL---NTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLF 487
            LA  L   G+++ DV+ +I  N     L    T++    +   V+ ++HD    EL    +  + ++VFCT+K+ +             K+        +   + E +I +   S+   P +   +  DV +IL SSGTTG PK VQ+T                         ++FL    +F      G +LL   F  +  F+  LF            F       + I S  V+ + +  + +VL  C  +F                     YG TE+ G   L+  N    G +   T   +  +    TG+ L  N +GE+ F K++    GYL   +E ++ F+ +G+  TGD  +Y ++G F+   R+ E+IK +G  V P ELE +L   H  + +VGVV   +++   +   +VVK       E +R  + K V   KR+ G +   KE +P+N+ GK+LR ++++L 
Sbjct:   26 LAHELQNIGIKQGDVLTIISQNHWKYLL----TLIAGFYVGAKVNLLNHDYTSGELKHIMSTCRPKVVFCTHKSLQALLELKNEDYFAPKIYIYDAPTSDYAVNFENLIESTNDSENFCPVEA--NPNDVSLILTSSGTTGFPKCVQLTNSNIRYTMTFMADPDLIDFNENESTIAFLPFFHIFGFAVGVGCVLLGVEFVILEKFVPDLFLKTIQNYKITKLFGVPPVFHFLIKSPKVQEYDISSMRDVL--CGASFLSKEIEELVVKKLNVVSVRQGYGMTEASGAITLIPKNAKKYGSLGKPTTGVLIKVCHTETGEVLPANSVGEIRF-KSDGVMKGYLGSDKETKQAFDGEGFMKTGDLGYYDDEGFFYIVGRLKEIIKYKGFQVSPAELENIL-LQHSAVKDVGVVGKPDERAGEVPVALVVKQADVTEEELVR-HVEKNVSAQKRLYGGVKFVKE-IPKNSSGKVLRMKLKELL 493          

Query:   78 DFLHKVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVIS-----ISVDSISHDTLMTE-----LNDTQAEIVFCTNKTFKKVKNCGC-----TIINMDTDIE----EMIAN-GCTSKVIVPKQDVFSLKDVFVILWSSGTTGQPKGVQMTVVSFLDSM--------------FATP--KVKGNML-LSANFGHISGFISSLF---------------WTFHFSTSTFYYISSDDVKHFGVVKL--------------FEVLKKCVPN-----FYGSTESGGGFLVSTNQHSNGG---VVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVLGAIIVVKNDKKINVETIRKELNKKV-----DEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLFK 488
            D   +    A  + + G++K D+V +   N  D  +P  AT+    +++     +++D   H   +++     +N+  AEI     K         C      II     ++      +AN  CT        D+       +I++SSGTTG PKGVQ++  S L+ M              + TP   + G+ L L + + HI    +  F               W    ++    ++  D +  + +  L               +++KK + N      YG TE GG   + ++  ++G    V+   +  I D+ TG+ LGPN+ GEL   K     TGY    E  + +F+K+GW H+GD  +Y E GE F   R+ E+IK +G  + P ++E LL++ H  ++EVGVV +      +   + +    K  N E   +EL+K V     D YK   G   L    LP    GK+ R +++ + K
Sbjct:   23 DICDRTIKCALWMQKHGVKKGDIVAICSHNHRDCIIPFLATLYLGAIVNPWDHLMNIDMARHFITLSQPKVIFVNEGSAEIALEAAKIELHHTKLVCFGYYPGIIPFSETLKYHDKSTVANFQCT--------DIDDPLHTGLIMFSSGTTGMPKGVQLSHKSILNIMELREGFPYGIQTQLWFTPLYWISGSFLNLKSIYFHIKKISAPEFNEKIACEIIEKYKVDWIMLSTSMANRFVRYDYLHDYDISNLKFAIIGGSALNRETQDIIKKYLSNTMIIQAYGMTELGGIITIQSSTATSGSCGIVIPNCQIKIIDIETGKTLGPNQTGELC-AKTWTMMTGYHKNCEATKNIFDKNGWLHSGDLAYYNENGEVFIVDRLKEIIKYKGYQISPNKIENLLQS-HPAVLEVGVVGI---PHPIYDELPIAFISKVPNKEVSEEELSKMVASNMMDIYKLRGGIKFLPS--LPHTPSGKISRKKLRAMAK 497          

Query:   78 DFLHKVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVIS-----ISVDSISHDTLMTE-----LNDTQAEIVFCTNKTFKKVKNCGC-----TIINMDTDIE----EMIAN-GCTSKVIVPKQDVFSLKDVFVILWSSGTTGQPKGVQMTVVSFLDSM--------------FATP--KVKGNML-LSANFGHISGFISSLF---------------WTFHFSTSTFYYISSDDVKHFGVVKL--------------FEVLKKCVPN-----FYGSTESGGGFLVSTNQHSNGG---VVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVLGAIIVVKNDKKINVETIRKELNKKV-----DEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLFK 488
            D   +    A  + + G++K D+V +   N  D  +P  AT+    +++     +++D   H   +++     +N+  AEI     K         C      II     ++      +AN  CT        D+       +I++SSGTTG PKGVQ++  S L+ M              + TP   + G+ L L + + HI    +  F               W    ++    ++  D +  + +  L               +++KK + N      YG TE GG   + ++  ++G    V+   +  I D+ TG+ LGPN+ GEL   K     TGY    E  + +F+K+GW H+GD  +Y E GE F   R+ E+IK +G  + P ++E LL++ H  ++EVGVV +      +   + +    K  N E   +EL+K V     D YK   G   L    LP    GK+ R +++ + K
Sbjct:   53 DICDRTIKCALWMQKHGVKKGDIVAICSHNHRDCIIPFLATLYLGAIVNPWDHLMNIDMARHFITLSQPKVIFVNEGSAEIALEAAKIELHHTKLVCFGYYPGIIPFSETLKYHDKSTVANFQCT--------DIDDPLHTGLIMFSSGTTGMPKGVQLSHKSILNIMELREGFPYGIQTQLWFTPLYWISGSFLNLKSIYFHIKKISAPEFNEKIACEIIEKYKVDWIMLSTSMANRFVRYDYLHDYDISNLKFAIIGGSALNRETQDIIKKYLSNTMIIQAYGMTELGGIITIQSSTATSGSCGIVIPNCQIKIIDIETGKTLGPNQTGELC-AKTWTMMTGYHKNCEATKNIFDKNGWLHSGDLAYYNENGEVFIVDRLKEIIKYKGYQISPNKIENLLQS-HPAVLEVGVVGI---PHPIYDELPIAFISKVPNKEVSEEELSKMVASNMMDIYKLRGGIKFLPS--LPHTPSGKISRKKLRAMAK 527          

Query:   72 VAHTLKDFLHKVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVIS-----ISVDSISHDTLMTE-----LNDTQAEIVFCTNKTFKKVKNCGC-----TIINMDTDIE----EMIAN-GCTSKVIVPKQDVFSLKDVFVILWSSGTTGQPKGVQMTVVSFLDSM--------------FATP--KVKGNML-LSANFGHISGFISSLF---------------WTFHFSTSTFYYISSDDVKHFGVVKL--------------FEVLKKCVPN-----FYGSTESGGGFLVSTNQHSNGG---VVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVLGAIIVVKNDKKINVETIRKELNKKV-----DEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLFK 488
            +     D   +    A  + + G++K D+V +   N  D  +P  AT+    +++     +++D   H   +++     +N+  AEI     K         C      II     ++      +AN  CT        D+       +I++SSGTTG PKGVQ++  S L+ M              + TP   + G+ L L + + HI    +  F               W    ++    ++  D +  + +  L               +++KK + N      YG TE GG   + ++  ++G    V+   +  I D+ TG+ LGPN+ GEL   K     TGY    E  + +F+K+GW H+GD  +Y E GE F   R+ E+IK +G  + P ++E LL++ H  ++EVGVV +      +   + +    K  N E   +EL+K V     D YK   G   L    LP    GK+ R +++ + K
Sbjct:   62 IEDNFSDICDRTIKCALWMQKHGVKKGDIVAICSHNHRDCIIPFLATLYLGAIVNPWDHLMNIDMARHFITLSQPKVIFVNEGSAEIALEAAKIELHHTKLVCFGYYPGIIPFSETLKYHDKSTVANFQCT--------DIDDPLHTGLIMFSSGTTGMPKGVQLSHKSILNIMELREGFPYGIQTQLWFTPLYWISGSFLNLKSIYFHIKKISAPEFNEKIACEIIEKYKVDWIMLSTSMANRFVRYDYLHDYDISNLKFAIIGGSALNRETQDIIKKYLSNTMIIQAYGMTELGGIITIQSSTATSGSCGIVIPNCQIKIIDIETGKTLGPNQTGELC-AKTWTMMTGYHKNCEATKNIFDKNGWLHSGDLAYYNENGEVFIVDRLKEIIKYKGYQISPNKIENLLQS-HPAVLEVGVVGI---PHPIYDELPIAFISKVPNKEVSEEELSKMVASNMMDIYKLRGGIKFLPS--LPHTPSGKISRKKLRAMAK 542          

Query:  187 VPKQDVFSLKDVFVILWSSGTTGQPKGVQMTVVSFLDS--MFATPK---VKGN--MLLSANFGHISGF---------------------------ISSLFWTFHFSTSTF------------YYISSDDVKHFGVVKLFEVLKKCVP---------NFYGSTESGGGFLV----STNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVLGAIIVVKNDKKINVETIRKELNKKVDE----YKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLF 487
            VP  D    K +  +++SSGTTG PKGV ++  + + +  + + P+   + GN  +L +A   H+SG                            I     T  F   T+            Y +SS  + + G   +  V+ + V            YG TE+ G   +    S +  S G  +A T   + D+NTG  LGP + GE+  +     S GYLN  E   K+++ +G+ HTGD  +YTE+G F+   R+ EMIKC    V P ELE LL   H+D+ EV V  V   +        VV ++     E +++ L K V +    +K + G L      +P++  GK LR  ++  F
Sbjct:   13 VPSGDP---KQLLALIYSSGTTGFPKGVMLSSKNIVANACIISDPRHRSLDGNDIVLGTAPLTHVSGLTMFNVSIAVGACMVLLPGSEPSITLPAIDKYKATVMFQFPTYIQKLVKSPLLEKYDVSSVRILYCGGSSMPSVVVRAVRTKLNIKALRQGYGLTETCGTVSLTPFNSEDAESIGKPLAMTRMKVVDVNTGLKLGPCEHGEIRVKGPTCVS-GYLNNPEATAKLYDSEGFLHTGDIGYYTEEGMFYVVDRMKEMIKCMDQQVAPAELEDLL-LKHEDVKEVAVAGVPHAEYGEAARAFVVLSNGHSGSEALKRRLFKLVADQSAPHKHLHGGLEFVSS-IPKSETGKNLRRALRDTF 370          

Query:  290 YGSTESGGGFLVST--NQH--SNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVLGAIIVVKND--KKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLFKSS 490
            YG TE   G + +   N H  S G +++RT+  I DL +G+ LGPN+ GEL +        GY N  +  ++M  +DGW  +GD  +Y E G F+   R+ E+IK +G  V P ELE +L   H  ++E  V+ + ++    L    VV+    + ++   IR  ++ KV  +K+I+G +    + LP+N +GK+LR E++  +  +
Sbjct:  283 YGLTEMSPGAMQTPLNNDHLGSCGRLISRTKAKIVDLESGKTLGPNQQGEL-YMTGPQVMKGYWNNPQATKEMIGEDGWLRSGDVAYYDEGGNFYIVDRLKELIKVKGLQVAPAELEDILSG-HPAVVEAAVIGIPDEHAGELPRAYVVRKPGMESVSDAEIRTYVDSKVSSHKQIKGGIEFC-DALPKNNLGKVLRRELRSQYAQA 486          

Query:  290 YGSTESGG----GFLVSTNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVLG-AIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLFKSSLA 492
            YG TES        +++    S G  V+RT   I DLNTG+ LGP + GE+          GY    +  E+  +  GW HTGD  +Y EQ +FF   R+ E+IK +G  V P ELE +L+  H  +++V V+ + +     L  A +V KN   ++ E I + ++ KV  +KR++G ++   + +P+   GKLLR E++ +  S ++
Sbjct:  284 YGMTESSPVTHMSPIINNEIGSFGEPVSRTRVKIMDLNTGESLGPGQEGEMCVFGPQVMK-GYYKNEKATEETIDSAGWLHTGDIAYYNEQNQFFIVDRLKELIKVKGLQVSPSELEDVLRR-HPAVLDVAVIGIPDDMSGELPRAYVVKKNGVSVSKEDIAEFVDAKVAPHKRLKGGVMFI-DAIPKTNTGKLLRRELKSMLLSQIS 488          

Query:  290 YGSTESG----GGFLVSTNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVLGAIIVVKND-KKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLFKSSL 491
            YG TES       F+ S+   S G V+   E+ + D +T + LGPN+ GE+  R       GY+      +   +  GW HTGD  +Y E G FF   R+ E+IK +G  V P ELE +L   H DIIE  V PV ++    L    VVK+    +  + + K +  KV  +KR+ G ++  K  +P+ A GK+LR E++K+ KS L
Sbjct:  332 YGMTESTLRTHSNFIGSSRDGSIGTVMPFCESIVVDPDTNKALGPNEEGEICVR-GPLIMKGYIGDESATKHTIDSQGWLHTGDIGYYDEDGFFFITDRMKELIKYKGLQVSPTELEQIL-LTHPDIIEAAVAPVPDEAAGELPRAYVVKSPGSTLTEDDVAKFVADKVSAHKRLRGGVVFIKA-VPKTATGKILRRELKKI-KSKL 534          

Query:   78 DFLHKVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISV-DSISHDTLMTELNDTQAEIVFCTNKTFKKVK------NCGCTIINMDTDIEEMIANGCTSKVIV----PKQDVFSLK--------DVFVILWSSGTTGQPKGVQMT----VVSFL---DSMFATPKVKGNMLLS-ANFGHISGFISSLFW---------------TFHFSTSTFYYIS--------------SDDVKHFGVVKLFEVLKKCVP-------------------NFYGSTESGGGFLVSTNQHSNGGVVARTETYIR----DLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVL-GAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLF 487
            D L     LAK     GLR++ V+ +   N    + PV A  L  GVI+ +V DS +   L+  LN ++ E+VFC+ K  K +       N    ++ +D+  E+M    C S  +     P  DV + K         V +I+ SSGTTG PKGV +T     V F+   D +F T  +    +LS   F H  G  ++L +                F  ST   Y I               S  V  + +  + EV     P                     YG TE+    L++ +     G   R   Y++    DL TG+ LGPNK GEL F K+     GY N  +  E+  +K+GW H+GD  +Y + G FF   R+ E+IK +G  V P ELE LL   H  I + GV  V ++    L GA IV++  K +  + I   + ++V   KRI G ++   + +P+ A GKL+RSE++KL 
Sbjct:   52 DILENSCRLAKCYENYGLRQNSVISVCSENSTIFFYPVIAA-LYMGVITATVNDSYTERELLETLNISKPELVFCSKKAIKNMMALKRNVNFIKKVVLLDSK-EDMGEAQCLSNFMARYSEPNLDVRNFKPRDFDAKEQVALIMSSSGTTGLPKGVVLTHRNLSVRFVHCKDPLFGTRTIPSTSILSIVPFHHAFGMFTTLSYFIVGLRVVLLKRFEEKFFLSTIEKYRIPTIVLAPPVMVFLAKSPLVDQYDLSSIREVATGGAPVGTEVAVAVAKRLKIGGILQGYGLTETCCAVLITPHDDVKTGSTGRVAPYVQAKIVDLTTGKSLGPNKRGELCF-KSEIIMKGYFNNKQATEEAIDKEGWLHSGDVGYYDDDGHFFVVDRLKELIKYKGYQVAPAELEWLL-LQHPSIKDAGVTGVPDEAAGELPGACIVLQEGKSLTEQEIIDYIAERVSPTKRIRGGVVFVDD-IPKGATGKLVRSELRKLL 536          

Query:   78 DFLHKVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISV-DSISHDTLMTELNDTQAEIVFCTNKTFKKVK------NCGCTIINMDTDIEEMIANGCTSKVIV----PKQDVFSLK--------DVFVILWSSGTTGQPKGVQMT----VVSFL---DSMFATPKVKGNMLLS-ANFGHISGFISSLFW---------------TFHFSTSTFYYIS--------------SDDVKHFGVVKLFEVLKKCVP-------------------NFYGSTESGGGFLVSTNQHSNGGVVARTETYIR----DLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVL-GAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLF 487
            D L     LAK     GLR++ V+ +   N    + PV A  L  GVI+ +V DS +   L+  LN ++ E+VFC+ K  K +       N    ++ +D+  E+M    C S  +     P  DV + K         V +I+ SSGTTG PKGV +T     V F+   D +F T  +    +LS   F H  G  ++L +                F  ST   Y I               S  V  + +  + EV     P                     YG TE+    L++ +     G   R   Y++    DL TG+ LGPNK GEL F K+     GY N  +  E+  +K+GW H+GD  +Y + G FF   R+ E+IK +G  V P ELE LL   H  I + GV  V ++    L GA IV++  K +  + I   + ++V   KRI G ++   + +P+ A GKL+RSE++KL 
Sbjct:   52 DILENSCRLAKCYENYGLRQNSVISVCSENSTIFFYPVIAA-LYMGVITATVNDSYTERELLETLNISKPELVFCSKKAIKNMMALKRNVNFIKKVVLLDSK-EDMGEAQCLSNFMARYSEPNLDVRNFKPRDFDAKEQVALIMSSSGTTGLPKGVVLTHRNLSVRFVHCKDPLFGTRTIPSTSILSIVPFHHAFGMFTTLSYFIVGLRVVLLKRFEEKFFLSTIEKYRIPTIVLAPPVMVFLAKSPLVDQYDLSSIREVATGGAPVGTEVAVAVAKRLKIGGILQGYGLTETCCAVLITPHDDVKTGSTGRVAPYVQAKIVDLTTGKSLGPNKRGELCF-KSEIIMKGYFNNKQATEEAIDKEGWLHSGDVGYYDDDGHFFVVDRLKELIKYKGYQVAPAELEWLL-LQHPSIKDAGVTGVPDEAAGELPGACIVLQEGKSLTEQEIIDYIAERVSPTKRIRGGVVFVDD-IPKGATGKLVRSELRKLL 536          

Query:   62 FPDETVS---DGPVAHTLKDFLHKVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDTQAEIVFCTNKTFKKVKNCGCTIINMDTDIEEMI----ANGCTSKVIV------PKQDVFSLKDVFVILWSSGTTGQPKGVQMT----VVSFLDSMFATPKVKGNMLLS-ANFGHISGFI----------SSLFWTFHFSTSTFY-YISSDDVKHFGVVKLFEVLKKCVP-------------------------------------NFYGSTESGGGFLVSTNQHSNGGVVART---ETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEI 483
            +PD   +   DG   HT       V   A  L  +G  K DV+ L+  N     +   A  L  G + +     + D L   LNDT A ++        K      T +   T +EE+I    A G TS   +      P+  +   +DV  +L SSG+TG PKGV +T    + + L +    P  +G  +L+   F H  G I          ++L     F   ++   I    V    VV    VL    P                                       YG TE+   F+   +  + G V   +   E  I D+ TG+ LG N+ GE++ R  +    GYLN  E   K+ E DG+ HTGD  H  E GE F   RI E+IK +G  V P+ELE +L + H ++ +  V+ V +++ + +    VV  +  +  E I   + ++V  YK+I     + +  +PR  +GK+ R  +
Sbjct:   28 YPDRLATVDVDGENGHTYGQLASAVRRAATGLGARGFGKGDVLALLAPNVPAYPVAYHAAALAGGTVVVLNPLDTADDLTAHLNDTGARLLVTVPSEVAK-----ATAVTARTKVEEVIVFGEAEGATSFSALLADGAPPEPAIDPARDVVTVLHSSGSTGYPKGVLLTHRNMIANVLQTSLVAPLDEGETVLAVPPFHHAFGLIMTMNASLLQGATLVTMPRFDPESYLKAIQEHRVTRLYVVPTIAVLLAKSPLVDRYDLSSLRSIVSGGAALDPGTAELCRRRLGVSIGQGYGLTEALVSFMQLADPVAPGSVGPTSPNIECKILDITTGEELGHNQDGEVLIRGPHVMK-GYLNAPEATAKVLEPDGFLHTGDLGHVDENGELFLVDRIKELIKYKGQQVSPVELEAVLMS-HPNVTDAAVIGVPDEEASEIPKGFVVTGE-PVTPEEIMAFVAERVAPYKKIRRIEFIDQ--IPRTPVGKIERRSL 508          

Query:   75 TLKDFLHKVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDTQAEIVFCTNKTFKKVKNCGCTIINMDTDIEEMIANGCTSKVI-----------VPKQDVFSLK--DVFVILWSSGTTGQPKGVQMTVVSFLDS--------------------------MFATPKV------KGNMLLS-ANF------GHISGFISSLFWTF--------------HFSTSTFYYISSDDVKHFGVVKLFEVLKKCVPNF-----YGSTESGG------GFLVSTNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVV-EKKQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLFKSSL 491
            T       V  LA   +  G+RK+DVV +   N     L   A     GV + +    + + +  ++ D+  +I+   N+ F K+K     ++ + +     I  G  SK++           V +     +K  D   +L+SSGTTG  KGV++T  +F+ +                          +F    +      +GN L+S A F       +I  F  +  W                 F  S+  YI S      G   L E   + +PN      YG TE+ G        L   N  S G +    E  I  + TG+   PN+ GE+  R  N    GYLN  +  ++  +K GW HTGD  ++ E G  +   RI E+IK +G  V P ELEGLL + H +I++  V+P   E+   V  A +V   +  I  + I+K + K+V  YKR+     ++   +P++A GK+LR E+ +  +S +
Sbjct:   56 TFSQLKSAVARLAHGFHRLGIRKNDVVLIFAPNSYQFPLCFLAVTAIGGVFTTANPLYTVNEVSKQIKDSNPKIIISVNQLFDKIKGFDLPVVLLGSKDTVEIPPGSNSKILSFDNVMELSEPVSEYPFVEIKQSDTAALLYSSGTTGTSKGVELTHGNFIAASLMVTMDQDLMGEYHGVFLCFLPMFHVFGLAVITYSQLQRGNALVSMARFELELVLKNIEKFRVTHLWVVPPVFLALSKQSIVKKFDLSSLKYIGSG-AAPLGK-DLMEECGRNIPNVLLMQGYGMTETCGIVSVEDPRLGKRNSGSAGMLAPGVEAQIVSVETGKSQPPNQQGEIWVRGPNMMK-GYLNNPQATKETIDKKGWVHTGDLGYFNEDGNLYVVDRIKELIKYKGFQVAPAELEGLLVS-HPEILDAVVIPFPDEEAGEVPIAFVVRSPNSSITEQDIQKFIAKQVAPYKRLRRVSFISL--VPKSAAGKILRRELVQQVRSKM 544          

Query:   75 TLKDFLHKVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDTQAEIVFCTNKTFKKVKNCGCTIINMDTDIEEMIANGCTSKVI-----------VPKQDVFSLK--DVFVILWSSGTTGQPKGVQMTVVSFLDS--------------------------MFATPKV------KGNMLLS-ANF------GHISGFISSLFWTF--------------HFSTSTFYYISSDDVKHFGVVKLFEVLKKCVPNF-----YGSTESGG------GFLVSTNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVV-EKKQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLFKSSL 491
            T       V  LA   +  G+RK+DVV +   N     L   A     GV + +    + + +  ++ D+  +I+   N+ F K+K     ++ + +     I  G  SK++           V +     +K  D   +L+SSGTTG  KGV++T  +F+ +                          +F    +      +GN L+S A F       +I  F  +  W                 F  S+  YI S      G   L E   + +PN      YG TE+ G        L   N  S G +    E  I  + TG+   PN+ GE+  R  N    GYLN  +  ++  +K  W HTGD  ++ E G  +   RI E+IK +G  V P ELEGLL + H DI++  V+P   E+   V  A +V   +  I  + I+K + K+V  YKR+     ++   +P++A GK+LR E+ +  +S +
Sbjct:   56 TFSQLKSAVARLAHGFHRLGIRKNDVVLIFAPNSYQFPLCFLAVTAIGGVFTTANPLYTVNEVSKQIKDSNPKIIISVNQLFDKIKGFDLPVVLLGSKDTVEIPPGSNSKILSFDNVMELSEPVSEYPFVEIKQSDTAALLYSSGTTGTSKGVELTHGNFIAASLMVTMDQDLMGEYHGVFLCFLPMFHVFGLAVITYSQLQRGNALVSMARFELELVLKNIEKFRVTHLWVVPPVFLALSKQSIVKKFDLSSLKYIGSG-AAPLGK-DLMEECGRNIPNVLLMQGYGMTETCGIVSVEDPRLGKRNSGSAGMLAPGVEAQIVSVETGKSQPPNQQGEIWVRGPNMMK-GYLNNPQATKETIDKKSWVHTGDLGYFNEDGNLYVVDRIKELIKYKGFQVAPAELEGLLVS-HPDILDAVVIPFPDEEAGEVPIAFVVRSPNSSITEQDIQKFIAKQVAPYKRLRRVSFISL--VPKSAAGKILRRELVQQVRSKM 544          

Query:   74 HTLKDFLHKVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDTQAEIVFCTNKTFKKVKNCGCTIINMDTDIEEMIANGCTSK--------VIVPKQDVFSLKDV------FVILWSSGTTGQPKGVQMT---VVSFL----DSMFATPKVKGNMLLSANFGHISGFISSLFWTFHFS---------------------TSTFYYISS----------------DDVKHF--GVVKLFE----VLKK-----CVPNFYGSTESGGGFLVSTNQHSNGG-------VVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVLGAIIVVKND-KKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLFKSSL 491
             T  D L +  ++A+ L+ +G+   DVV +   N  D  LPV A+       +      +   L+  +N ++  I+FC++   K V      I +    ++E++  G             +  K   F L DV        I  SSGTTG PKGV +T   ++S L    D  F   K    +L      H   FI  L  T H S                      +T   + S                  V+H   G   L +    +LKK      +   YG TE+    LV T    NG        +VA  +  + DL TG++LGPNK GEL F K      GY   ++E   +F+ DG+ HTGD  +Y + G F+   R+ E+IK +G  V P ELE +L   H  + + GV+ V ++    L    VVK    ++  + I K +  +V   KR+ G +L   + +P+   GK+LR E++ + KS L
Sbjct:   45 RTFSDILTRSLSVAECLHIRGVTIGDVVGICSENNLDFILPVLASYYIGATCAPLNPYYTTRELLHAVNISKPRIIFCSDGALKSVDE----ISHQVGFLKEIVTFGFPLSHKHTPFISFVRDKSRSFQLPDVNDLNITAAIQCSSGTTGLPKGVMLTQRNILSILQTANDPRFTITKPGDVLLALLPMFHSYAFICQLISTTHGSKVVVMNKFEEELFLRSIQNHKITTLMLVPSLVVFLAKAKIVDEYDLSSVQHVFSGAAPLSKESETLLKKRLRVQSIKQAYGMTETT---LVVTLPPPNGNKSGSSGILVAGVKCKVVDLETGRNLGPNKKGELCF-KGPQIMKGYCGNAQETSAIFDADGFLHTGDVGYYDDDGFFYIVDRVKELIKYKGYQVPPAELEAVL-INHPAVKDAGVIGVPDEAAGELPLAFVVKQPGARVTEDEIIKYMAGQVSPQKRLRGGVLFV-DSIPKTNSGKILRKELRSMLKSKL 529          

Query:   68 SDGPVAHTLKDFLHKVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDTQAEIVFCTNKTFKKVK--NCGCTIINMDTDIEEMIANGCTSKVIVPKQDVFS--------LKDVFVILWSSGTTGQPKGVQMTVVSFLDS--------------------------MFATPKV------KGNMLLS-ANF------GHISGFISSLFWTF--------------HFSTSTFYYISSDDVKHFGVVKLFEVLKKCVPNF-----YGSTESGG------GFLVSTNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVV-EKKQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLFKSSL 491
            SD   + T  +    V  LA      G+RK+DVV +   N     L   A     GV + +    +++ +  ++ D+  +I+    + F K+K  N    ++     + E  +   T   ++   D  S          D   +L+SSGTTG  KGV++T  +F+ +                          +F    V      +GN ++S A F       +I  +  +  W                 +  S+  YI S      G   L E   K +PN      YG TE+ G        L   N  S G +    E  I  + TG+   PN++GE+  R  N    GYLN  +  ++  ++ GW HTGD  ++ E G  F   RI E+IK +G  V P ELEGLL + H +I++  V+P   E+   V  A +V   D  I  E I+K + K+V  YKR+     ++   +P++A GK+LR E+ +  +S +
Sbjct:   49 SDSGDSLTFSELKSSVSRLAHGFLRLGIRKNDVVLIFAPNSYQFPLCFLAVSAIGGVFTTANPLYTNNEVSKQVRDSNPKIIISVEQLFDKIKGFNLPVVLLGSGESVPESNSKILTFNNVMELSDPVSDLPVVDIKQSDTAALLYSSGTTGISKGVELTHGNFIAASLMVTMDQDLMGEYHGVFLCFLPMFHVFGLAVVTYSQLQRGNAVISMAKFELETLLKNIDKYRVTQLWVVPPVFLALAKQNIVKKYDLSSLKYIGSG-AAPLGK-DLMEECGKNIPNVLLMQGYGMTETTGIVSVEDPRLGKRNSGSAGMLSPGVEAQIVSVETGKFQPPNQLGEIWVRGPNMMK-GYLNNPQATKETIDRKGWVHTGDLGYFNEDGNLFVVDRIKELIKYKGFQVAPAELEGLLVS-HPEILDAVVIPFPDEEAGEVPIAFVVRSPDSSITEEVIQKFIAKQVAPYKRLRRVSFISS--VPKSAAGKILRRELVQQVRSKM 541          

Query:   86 LAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISV-DSISHDTLMTELNDTQAEIVFCTNKTF------KKVKNCGCTIINMDTDIEEMIANGCTSKVIVPKQDV---------FSLKD-VFVILWSSGTTGQPKGVQMT----VVSFL---DSMFATPKVKGNMLLS-ANFGHISGFISSLFWTF---------HFSTSTF--------------------YYISSDDVKHFGVVKLFEVLKKCVP-------------------NFYGSTESGGGFLVSTNQH----SNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVLGAIIVVKND-KKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKL 486
            LA+ L   G +++DV+ +   N    + P+ A  LC GV+S  + D+ +   L   LN ++  I+FC+ K        KK  +C   II +D + E++  N   S  I+   D          F   D V  I+ SSGTTG PKGV +T     V F    D    T  + G  +LS   F H  GF ++L +            F    F                    +   S  V  + +  L E+     P                     YG TE+      + N      S+G VV      + +++ G+ LGPN +GEL F K      GY    +  ++  ++DGW HTGD  +Y ++G F+   R+ E+IK +G  V P ELEGLL   H  I +  V+ + ++    L A  VVK   KK++ + +   +  +V   K + G +    E +P++A GK++R  +++L
Sbjct:   61 LAQCLQRCGYKRNDVISVCSENNLHFFSPILAA-LCIGVVSAPLNDNYTQGELHNALNISKPGIIFCSEKVLPRMLEVKKQFSCIRRIILLDAE-EDVGENESLSNFILRNSDESFRNFKPLDFDPDDQVAAIMCSSGTTGLPKGVMITHKNLAVRFTHVRDPRTGTQTIPGTTVLSFMPFFHGFGFCTNLGYFLVGNRIVMLKRFQPELFLRSIQDYEVRSVLAVPPIILFLAKSPIVDKYDLTSLKEIGVGAAPLGKEVGEAVAKRLNLEGIRQGYGLTEATLAVTFTPNNEFRPGSSGTVVPLMSAKVINIDNGESLGPNVVGELCF-KGGLVMRGYAGNIKATKEAIDEDGWLHTGDLGYYDKEGHFYIVDRLKELIKYKGFQVPPAELEGLL-LKHPCIKDAAVIGIPDELAGELPAAFVVKQPGKKLSEKEVFDYIANQVSSPKHLRGGVRFIDE-IPKSATGKIVRKALREL 534          

Query:   83 VPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDTQAEIVFCTNKTFKKVKNCGCTIINMDTDIEEMIANGCTSKVIV---------PKQD--VFSLK--DVFVILWSSGTTGQPKGVQMTVVSFLDSMFAT------------------PKV--------------KGNMLLS-------ANFGHISGFISSLFWTF--------------HFSTSTFYYISSDDVKHFGVVKLFEVLKKCVPNF-----YGSTESGG------GFLVSTNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVLGAIIVVKNDK-KINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLFKSSL 491
            V  LA+     G+RK+DVV +   N     L   A     GV + +    + + +  ++ D+  +++    + F KVK     ++ + +  E +      SK++          P  D  V  +K  D   +L+SSGTTG  KGV++T  +F+ +   T                  P                +GN L+S       A   +I  +  +  W                 +  S+  YI S      G   L E   K +PN      YG TE+ G        L   N  S G +    E  I  + TG+   PN+ GE+  R AN    GY N  +  ++  +K GW HTGD  ++ E G  F   RI E+IK +G  V P ELEGLL + H +I++  V+P  +++   +    VV++ K  I  E I+K + K+V  YKR+     ++   +P++A GK+LR E+ +  +S +
Sbjct:   64 VSRLAQGFLRLGIRKNDVVLIFAPNSYQFPLCFLAVSAIGGVFTTANPLYTTNEVSKQIKDSNPKLIVSVERLFDKVKGFNLPVVLLGSG-ESVQIPESDSKILTFDNVMELSDPVSDLPVVDIKQSDTAALLYSSGTTGISKGVELTHGNFVAASLMTTMDQDLMGEYHGVFLCFLPMFHVFGLAVIAYSQLQRGNALISMARFELEALLKNIEKYRVTQLWVVPPVFLALSKQSIVKKYDLSSLKYIGSG-AAPLGK-DLMEECGKNIPNIVLMQGYGMTETCGIVSVEDPRLGKRNSGSAGMLAPGVEAQIVSVETGKSQPPNQQGEIWVRGANMMK-GYFNNPQATKETIDKKGWVHTGDLGYFNEDGNLFVVDRIKELIKYKGFQVAPAELEGLLVS-HPEILDAVVIPFPDEEAGEVPIAFVVRSPKSSITQEDIQKFIAKQVAPYKRLRRVSFISS--VPKSAAGKILRRELVQQVRSKM 543          

Query:   75 TLKDFLHKVPALAKSLYEK-GLRKSDVVHLIIGNRADIYLPV-FATILCQGV-ISISVDSISHDTLMTELNDTQAEIVFCTNKTFKKVKNCGCTIINMDT-DIEEMIANGCTSKVIVPKQDVFSLKDVFVILWSSGTTGQPKGVQMT---VVSFLDSMFATPKVKGNM----LLSANFGHISGFI---------SSLFWTFHFSTSTF-------------------------------YYISSDDVKHFGVVKL----FEVLKKCVPNF-----YGSTESGGGFLVSTNQH------SNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVV-EKKQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKL 486
            +  + +H    LA SL  +  L+K D   ++  N   I++P+ + ++   GV IS S    S   ++ + N ++  I F T++T  K+ +     I +D+ + E ++ +     V   ++      D   IL+SSGTTG+ KGV +T    +S L +  AT  VK  +    L +  + H  GF+          +L     F  S                                 Y +SS +V   G   L     E+ K+  PN      YG TE+      +          + G +++  +  I D +TG  L P+  GEL  R  +    GY+   E      +  GW  TGD  +  + G  FF  RI E+IKC+G  V P ELE LL++ + DIIE  V+P   E+   V  A +V +N   I+   I+  + ++V  YKR+     +  E LPRNA GK+LR E+  L
Sbjct:   71 SFPELIHFTETLASSLLNRFRLKKGDTAFILSPN--SIHIPILYLSLFSLGVVISPSNPLSSEQEILHQTNLSKPVIAFVTSQTAHKIPDSVKKTILLDSPEFESLMTSQSQGTVNGLERVRVYQSDPAAILYSSGTTGRFKGVLLTHRNFISMLAATIATRGVKNKITAVTLCTVPYFHAYGFVYCLRFAATGDTLMSMGRFDLSAMLRAIQDYRVSHVALAPPVVVAMAKNVGAMDGYDLSSLEVVACGGAPLRKSVLELFKERFPNVHIAQGYGLTETTARIFATIGPKESEVIGATGKLISNCQAKIVDPDTGVSLPPSSPGELWVR-GDTIMKGYIGDDEATAATLDSGGWLRTGDLCYIDKDGFLFFVDRIKELIKCKGYQVAPAELEHLLQS-NPDIIEAAVIPYPDEEAGQVPVAFVVRQNGSIIDEPKIKDFVARQVAPYKRLRQVTFI--ESLPRNATGKVLRRELINL 543          

Query:   86 LAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDTQAEIVFCTNKTFKKV-KNC-GCTIINMDTDI--------EEMIANGCTSKVIVPKQDVFSLKDVFVILWSSGTTGQPKGVQMTVVSFLDSMFATPKVKGNMLLSANFGHISGF----ISSLFWTF--------------HFSTSTFYY------ISSDDVKHFGVVK-----------------------LFEVLKKCVPN------FYGSTESGGGFLVSTNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKK-QTVLGAIIVVKNDKKINVETIRK-ELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQ 484
            +A +L   GL+  DVV L + N  D YL  F   LC  ++S+S  S+   ++ +++ D   +IVFCT   F +V + C GC +I +D +         E  +A G  + +  P+ ++   +D  +I WSSGTTG PKG+Q +  + ++ M A    + N+L +  F HI GF     +S+F T+              H   + + Y      I S    H                            L E L++ +PN      +YG TE G     S +  + G +    E  I +  T + LGPN+IGE+ + K   T+ GY+NR   N++ F   G+  TGD  ++ E+G  +FH R+ ++IK + +HVYP +LE +++  H D++EV +  + E   Q ++ A++V +   ++N + +R   L + ++ YK++ G +      LPRN  GK++R  ++
Sbjct:   73 VASALKANGLQAGDVVQLYLPNSVDYYLIAFGAWLCGAIVSMSDSSLKCKSIESQIEDVHPKIVFCTEDNFAEVEQGCPGCPLIVLDHEFGPCKHLTYEGFLAMGQVTAMESPEVNI---EDCVLIFWSSGTTGNPKGIQHSHRNMINFMVADDFTRANLLATTMFPHIGGFTIPICASIFGTYDIVFYGHNFPVESHHIFEAIYKYKPQFLVIGSHHAVHLASAPHPKNMDLSSVKAVYPIGSATYAGLLEDLRQHLPNLTDILNYYGLTEIGA-LSNSLSSFNLGTLRDGREAKIVNPETNELLGPNEIGEI-WGKTPTTTIGYVNRPTLNKESFGLGGFFRTGDLGYFDEEGLLYFHDRLKDLIKYKNNHVYPGDLEAIIQK-HPDVVEVAIFGIPEPTVQELVSALVVKRPGSQLNEKDVRDLVLKEDLEYYKQVRGPIKFVDR-LPRNHRGKIVRRTLK 529          

Query:   87 AKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDTQAEIVFCTNKTFKKVKNC--GCTIINMDTD---------IEEMIANGCTSKVIVPKQDVFSLKDVFVILWSSGTTGQPKGVQMTVVSFLDSMFATPKVKGN--MLLSANFGHISGF-----------ISSLFWTF-HFSTSTFYYISSDDVK--------HFGV---------------------------VKLFEVLK------KCVPNFYGSTESGGGFLVSTNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKK-QTVLGAIIVVKNDKKINVETIRKE-LNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQ 484
            A +  + GL   DVV   + N  D Y+P+F   LC  ++S++  ++    + +++ DTQ +++ C       ++    G T+I ++TD          E  +  G      +P   V  +    +ILWSSGTTG PKG+Q +  + L+     P V  N     +  F H+ G+           ++ +F  F H  T      ++   K        H GV                             L E LK      K + N+YG TE G   +  T   S G ++   E  I D NT + LG N+IGE M+ K   T+ GY+NR   NEK F  DG+  TGD  +Y E G  +FH R+ ++IK + + VYP+ELE +L   H +I EV V    E   Q ++ A +V      ++   +R   ++  VD+ K I G +      LP+NA GK+LR  +Q
Sbjct:  149 ASAFTKLGLEAGDVVQFYLPNCVDYYIPLFGAWLCGAIVSLTSSTLKVPAIQSQIEDTQPKVLLCYQGNLATIEQAITGQTLIALNTDGDESTDHLSYERFLDMGEAEPFQLP---VTQVDQCTMILWSSGTTGLPKGIQHSHRNMLN--LVQPIVSPNPYSYTTTMFYHMGGYHLAVSGAIFGNVNVVFHGFNHIVTGVEIMEAAHKYKPNLMFIWTHHGVELAMAKPRPDLDLSSVTAISPLGSSLDTNLLEDLKPKFPNCKAILNYYGMTELGSISMGHTPT-SMGSLLNGREVKIVDPNTQELLGANQIGE-MWVKTPITTIGYINRPGLNEKSFAPDGFYKTGDLGYYDEAGLLYFHDRLKDLIKYKNNQVYPVELETVLME-HPEIAEVAVYGTPEPAVQELISACVVKTPGSTLSEADVRAWVVHADVDDGKLIRGPVKFVSH-LPKNAHGKILRKLLQ 605          

Query:    3 NIQHSKISEDYVLTTKS--DDNRTLQAEYNQNLAECFLDKITKYLEVNEDKELLVNCGKRFFPDETVSDGPVAHTLKDFLHKVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDTQAEIVFCTNKTFKKV--------KNCGCTIINMDTDIEEMIANG---CTSKVIV---------PKQDVFSLKDVFVILWSSGTTGQPKGVQMTVVSFLDSM------FATPKVKGNMLLSANFGHISGFISSLFWTFHFSTSTFYYISSDDVKHFGVV----------KLF-------------EV--------------------------LKKCVPNF-----YGSTESGGGFLVSTNQHSN--GGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEK-KQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEI 483
            ++Q S +  D +++ K+  D N  L    ++ + E +   I   +E NE  +       RF+ D           + D   K   +AK     G+ + D+V + + N  +    V  T +C  V S++   +S  T+  ++ DTQA+++ CT    +K          +    +++ D +  + I N      S+++          P  D FSL D+ +I WSSGTTG PKG+Q++       M      F+ P      LL+    HISG I  L  T  F+    ++  +D V+   ++          K+F             EV                          LK   PN      Y  TE G  F VS +   N  G V   ++  I D  T   LGPN+ GE++ +     + GY  +  E  +  + DG+ HTGDF H+ EQG  ++  R+ E+IK + +H+YP+ELE L++ +   + EVGV    +   Q +  A++ +     +    I+K + ++VD++K++ G +     PLPR+A+GK++R+++
Sbjct:   45 SLQMSLVGSDNIVSAKTPVDHNHVLPTAPDRPMVEAYFLGIKARIE-NEGNQ-------RFYTDGVTGK---YLNISDLEVKARQVAKLFTSMGVGRGDIVQISVPNSLEFVPLVLGTWVCGAVPSLTDPDLSVATVRAQVEDTQAKVIICTPGKVRKFHEALDQLHASTQLVLLHDDEENLQFIQNADIPVLSQLLAICDQLPNPKPISD-FSLDDIAIICWSSGTTGTPKGIQVSFQLVKHRMKPSANDFSAPD-----LLTTCMFHISG-IGKLLMT-AFNQQVIFFQDADLVQDISLILQACHKYRAGKVFLGSHHCAQLVNMSEVPSGLDLSCVRLVYPVGARVHNAMLADLKAFFPNMTLCNCYTMTELG--FFVSYSFDPNCLGSVAEGSQVKIVDPVTKMALGPNQTGEIVVKPPYPFA-GYYKQPLETTRFCDPDGFCHTGDFGHFDEQGLLYYDGRMKEIIKYRNNHIYPMELENLIQHL-PGVAEVGVYGQPDPASQELAVAVVRLAPGATLREAEIKKHVAEQVDDFKQLRGGVRFVDVPLPRSAVGKVMRNKL 587          

Query:   76 LKDFLHKVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDTQAEIVFCTNKTFKKVKNCGC--TIINMDT--------DIEEMIANGCTSKVIVPKQDVFSLKDVFVILWSSGTTGQPKGVQMTVVSFLDSMFATPKVKGNMLLSANFGHISGFI----SSLFWTF--------------------------------HFSTSTFYYISSDDVKHFGVVKLFEV-----------LKKCVPN------FYGSTESGGGFLVSTNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVE-KKQTVLGAIIVVKNDKKINVETIRKELNKK-VDEYKRIEGQLLLTKEPLPRNAMGK 477
            +K   ++V +  K+L   G+   DVV L + N  D Y+ +F   LC  ++S+   ++   ++ +++ D+Q ++VFCT     +V       + I + +          E  +A G +  + VPK +     D  +I WSSGTTG+PKG++ +  S ++ M A+    GNM ++  F HI GF      S+F T+                                H +       +  DV    V  ++ +           L++ +PN      FYG TE G       +Q++ G ++   E    +  T + LGPN++GE+ + K    + GYLN+ + ++      G+  TGD  ++ E+G  FF  R+ ++IK + +HVYP ++E L+   H DI+EV V  + E   Q ++ A++V     K+  + ++  + K+ ++ YK I G +      LPRN   +
Sbjct:   66 IKPLSYQVASAFKAL---GIGAGDVVQLYLPNSIDYYIVIFGAWLCGAIVSMCDSTMKAKSIESQVKDSQPKLVFCTGDNLDEVMKGSSKQSFIVLASKPGAKDHMSYESFLAKGNSESIEVPKSNP---DDCTLIFWSSGTTGRPKGIKHSQKSVVNLMQASLFAPGNMFVTTMFTHIGGFTMPLCGSIFGTYDIVFHGNDFVVECQHIFEAINKYKPHFLVLGAHHAVHMVSAPTPKDVDLSSVEMIYPIGSSTYTGVLEDLRQILPNLSVILNFYGMTEIGT-LTTGISQNNLGKLLGGREAKFINPETNKVLGPNQVGEI-WGKTPIMTLGYLNQPDLDKHSIGPGGFFRTGDLGYFDEEGTLFFQERLKDLIKYKNNHVYPADIE-LIIQRHPDIVEVAVFGLPELTVQELVSALVVKMPGSKLTEDDVKALVAKEDLESYKLIRGPVKFVPS-LPRNTQAR 522          

Query:   20 DDNRTLQAE--YNQNLAECFLDKITKYLEVNEDKELLVNCG---KRFFPDETVSDGPVAHTLKDFLHKVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDTQAEIVFCTNKTFKKVKNC--GCTIINMDTD--------IEEMIANGCTSKVIVPKQDVFSLKDVFVILWSSGTTGQPKGVQMTVVSFLDSMFATPKVKGNMLLSANFGHISGF------------------------------------ISSLF-WTFHFSTSTFYYISSD-DVKHFGVV---------KLFEVLKKCVPNF------YGSTESG--GGFLVSTNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEKKQTVLGAIIVVKNDKKINVETIRKELNKK--VDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKL 486
            D+++ L+A+  Y+        D I K+  + E  + LV  G   + +  D  V D P    L +        A +  + GL+  DVV   + N  D Y PVF   L   ++S++  ++   T+ +++ DTQ + +FC       V+    G T+I ++T+         E+ +A G   +V +P  DV    +V +ILW+SGTTG PKG++ +  + ++ +         +  +  F H+SG+                                     S +F WT H           D D+    ++          L   L+   PN       YG TE G     L STN    G +    E  I D +T +  GP+ IGE+  +   AT  G++NR    E+ F   G+  TGD  +Y E+G  +FH R+ ++IK + S +YP E+E +L   H DI EV V    E     L ++ VVK+      E   KEL  K  +D+   I G +      +P+NA GK+LR  +++ 
Sbjct:    4 DESKILKAKLPYDPVCKAKPSDSIVKH--ILEKIDALVQSGQGDRPWLTDICVLDQPQVQRLSEVRPLAFQAASAFKKLGLKAGDVVQFYLPNSIDYYGPVFGAWLNGAIVSLTCSTLKAPTIRSQIEDTQPKYLFCYQSNLAAVEQASTGQTLIVLNTNGADCGHLSFEKFMAMGDDVEVQLPTPDV---DEVTMILWTSGTTGLPKGIKHSHRNLINLVVPIVSSTSYLYSTTVFYHMSGYNLVVSGGVFGNADIVFHGNNYPFESRDIMVAAHKYKPSLMFTWTHHIVQLGLAEPQKDLDLSSVLIIGPLGSSVDTSLLNDLRTKFPNLQGVMNIYGMTEIGSIATSLCSTNL---GPIFNGREVKIVDPDTQELQGPHGIGEIWAKTPMAT-VGFVNRPGLTEESFAPGGFYKTGDLGYYDEKGILYFHDRLKDLIKYKNSQIYPSEIEAVLME-HPDIDEVAVYGTPEPAVQELVSVCVVKSPSSKLTEAEVKELVAKADLDDSLLIRGPVKFVSH-IPKNAHGKILRKSLREF 531          

Query:   86 LAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDTQAEIVFCTNKTFKKVKNC------------GCTIINMD-TDIEEMIANGCTSKVIVPKQDVFSLKDVFVILWSSGTTGQPKGVQMTVVSFLDSMFATPKV-----KGNMLLSANFGHISGFISSLFWTFHFSTSTFYYISSDDVKH------------------------------------FGVVKLFEVLKKCVP------------------NFYGSTESGGGFLVSTNQHSN--GGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVV-PVVEKKQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLFKSSL 491
            L     + G +K DV+H+++GN    +   F   +  G +S+   ++   ++  +LN  Q   V C   T K V                C   N +  D+ +++ N   ++   P  D+   +DV VI WSSGTTG PK +  +  S ++  F  P +     K N++ +  F H+ GF + +     + T    +  S  + H                                    F  ++        VP                  N YG TESG   ++S    S   G ++      + +++TG+   P++ GEL + K  A   GYLNR ++N    + +G+ H+GD  +YT  G+ +F  R+ E+IK + +H+ P ELE +L+  H  + E  V     ++ Q ++ A++V+K   +     + + +N++V +YKRI G ++   E +PRN++GKL+R E++   +  +
Sbjct:  137 LGAFFLQNGCKKGDVIHVLLGNHNMTFPICFGGWILGGCMSLGDVNLEPRSVAEQLNTCQTRFVICMPDTQKLVTEALKLASRPQDIKTFCLGKNEEFEDLNDLLRNIDPTECPDP-MDMDVEEDVPVIFWSSGTTGHPKAICHSHNSAIN--FGGPAINFLVPKTNVVTTTCFFHVGGFFTGINACLKYQTYYHMFGPSFRLDHLLRAMSKLKPKTLAIGSHHYVQLSEYDGFHDANPDDFDSIEFLAPAGAAVPQSCEAIYKEKCRNLKGVLNAYGQTESG---IISAGVSSQALGSILPNIRVKVENVSTGERCAPHEEGELCY-KTPAMMKGYLNRPKDNADFLDFEGFGHSGDIVYYTPDGDIYFVDRLKELIKYKNNHIAPTELEDILQR-HPAVQESLVFGKHNDEVQELVSAVVVLKPKHQATEAELIEFVNREVTDYKRIRGDIIFRDE-IPRNSVGKLMRREMRDWARHQM 608          

Query:  278 LFEVLKKCVPNFYGSTESGGGFLVSTNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEK-KQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLF 487
            +F  LK  V N Y  TE G     ST     G V   T   I D +T + LG N++GE+M  K      GYLNR +E E   + DG+ HTGD  HY E G  FF  R+ E+IK +G H+YP+E+E +++ +   + EV V    +   Q ++ A++V      +N  TI   + + VD+YKRI G ++     LPRN++GK++R   + ++
Sbjct:  636 VFPALKN-VFNLYSLTEFGALITFSTTPRHLGSVAPGTTVKIVDSDTQETLGANQVGEIM-AKGTRIMMGYLNRPKETEACLDSDGFLHTGDLGHYDENGIMFFDGRLKELIKFEGKHIYPMEIEEIIRKL-PGVSEVAVFGKPDPINQELVTAMVVRAEGSNVNENTILNLVTQHVDDYKRIRGGVIFVPS-LPRNSIGKIMRRHAKTMY 842          

Query:   11 EDYVLTTK-SDDNRTLQAEYNQNLAECFLDKITKYLEVNEDKELLVNCG---KRFFPDETVSDGPVAHTLKDFLHKVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDTQAEIVFCTNKTFKKVKNCGCTIINMDTDIEEMIANGCTSKVIVPKQDVFS-------------------LKDVFVILWSSGTTGQPKGVQMT--VVSFLDSMFATPKVKGNMLLSANFGHISGF 247
            +D VL +K  +DN  +     ++L E    K+ + +E N D + L+NC    +    DE   D  +   ++    K   L +S+   G    DV+HL++ N  + + PV  T+LCQGV+S+    +  + +  ++ ++ A+ V C      +V+         D  ++ ++   C  +   P   V+S                   +     I+WSSGTTG  KG+Q +  +++ + +    P     +L S  F H  GF
Sbjct:    5 KDKVLYSKMPEDNSIIPDIVKESLVEALFQKVQQNIETNGDFKFLINCDLGLRGLTEDEVGLDCRMGSEMEPMSRKSAKLLRSM---GFEFQDVLHLVLPNTTEYFFPVLGTLLCQGVVSLGDPDLKPELMRYQIQESGAKFVVCHPGNLAQVRKA-----TRDLMVKILVVRDCPEE---PDNHVYSFCQQLAKVDDAQFVSDHLDIDQRMAIIWSSGTTGMLKGIQHSFRIIANIINRGYGPLSAQTILQSTCFFHAGGF 255          

Query:  278 LFEVLKKCVPNFYGSTESGGGFLVSTNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEK-KQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEIQKLF 487
            +F  LK  V N Y  TE G     ST     G V   T   I D +T + LG N++GE+M  K      GYLNR +E E     DG+ HTGD  HY E G  FF  R+ E+IK +  H+YP+E+E +++ +   + EV V    +   Q ++ A++V      +N +TI   + + VD+YKRI G ++     LPRN++GK++R  ++ ++
Sbjct:  348 VFPALKN-VFNLYSLTEFGALITFSTTPRHLGSVAPGTTVKIVDSDTQETLGANQVGEIM-AKGTRIMMGYLNRPKETEACLNSDGFLHTGDLGHYDEDGIMFFDGRLKELIKFENKHLYPMEIEEIIRKL-PGVSEVAVFGKPDPISQELVTAVVVKSEGSNVNEKTILDLVTQHVDDYKRIRGGVIFVPS-LPRNSIGKIMRRHVKTMY 554          

Query:   11 EDYVLTTK-SDDNRTLQAEYNQNLAECFLDKITKYLEVNEDKELLVNCG---KRFFPDETVSDGPVAHTLKDFLHKVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDTQAEIVFCTNKTFKKVKNCGCTII-------NMDTDIEEMIANGCTSKVIVPK----QDVFSLKDVFVILWSSGTTGQPKGVQ 215
            +D VL +K  +DN  +     ++L E    K+ + +E N D + L+NC    +    DE   D  +   ++    K   L +S+   G    DV+HL + N  + + PV  T LCQGV+S+    +  + +  ++ +++A+ V C      +V+     ++       +   D +  + + C     V       D   +     I+WSSGTTG PKG+Q
Sbjct:    5 KDKVLYSKMPEDNSIIPDIVKESLVEALFQKVQQNIETNGDFKFLINCNLGLRGLAEDEVGLDCRMGSEMEPMSRKTAKLLRSM---GFEFQDVLHLALPNTTEYFFPVLGTFLCQGVVSLGDPDLKPELMRYQILESRAKFVVCHPGNLAQVRKATRDLMVKILVVRDCPEDPDNHVYSFCQQLAKVDDAQFVSDHLDIDQRMAIIWSSGTTGMPKGIQ 221          

Query:  288 NFYGSTESGGGFLV--STNQHSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVVEK-KQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRS 481
            N Y  TE G  FLV  S + H  G +    +  I+D  T   LGP + GE++  K      GY N+ EE  K  + DG+ HTGDF HY E+G  +   R+ E+IK + +HVYP+ELE L++ +  ++ EVGV    +   Q +  A++ +    ++  E I+K + + VD YK++ G +  T  PLP+NAMGK +R+
Sbjct:  416 NCYSMTELG--FLVANSMDPHCLGSLAEGAQVKIQDPVTQTALGPLQTGEILV-KPPYPFPGYYNKPEETAKFCDSDGFCHTGDFGHYDEKGMLYLDGRMKEVIKYRNNHVYPMELENLIQDL-PEVAEVGVYGKPDPASQELAVAVVRLVPGAQLTEEAIQKHVAENVDNYKQLRGGVRFTNAPLPKNAMGKPVRN 608          

Query:   86 LAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDTLMTELNDTQAEIVFCTNKT----FKKVK--NCGCTIINMD--TDIEEMIANGCT--SKVIV---------PKQDVFSLKDVFVILWSSGTTGQPKGVQMT 217
            LAK     G+++ D+V + I N  +    V  T +C  + S++   +S  TL  ++ DT+A+I+ CT+       K +K  + G  I+ +D    ++EM   G +  S+++          P +D FSL D   I WSSGTTG PKG+ ++
Sbjct:  143 LAKLFTSLGVKRGDIVQISIPNDLEFSSLVLGTWVCGAIPSMTDPDLSVTTLQAQVEDTKAKIIICTSSKVEMFLKAIKQTSTGAQIVVLDDAAHVQEMKDAGLSTLSQLLAGCDQLPDPEPVKD-FSLDDTAFICWSSGTTGTPKGICLS 292          

Query:   82 KVPALAKSLYEKGLRKSDVVHLIIGNRADIYLPVFATILCQGVISISVDSISHDT-LMTELNDTQAEIVFCTNKTFKKVK----------NCGCTIINM---DTDIE---EMIANGCTSKVIVPKQDVFSLK-DVFVILWSSGTTGQPKGVQMT---VVS------------FLDSMFATPKVKGNMLLSANFGHISGFISSLFWTFH----------FSTSTF--------------------YYISSDDVK--HFGVVK------------LFEVLKKCVPNF-----YGSTE-SGGGFLVSTNQ---HSNGGVVARTETYIRDLNTGQHLGPNKIGELMFRKANATSTGYLNRSEENEKMFEKDGWTHTGDFFHYTEQGEFFFHSRINEMIKCQGSHVYPIELEGLLKAMHDDIIEVGVVPVV-EKKQTVLGAIIVVKNDKKINVETIRKELNKKVDEYKRIEGQLLLTKEPLPRNAMGKLLRSEI 483
            +V  +A +LY+ G R  DV+ L + N  D  L V       G+I+ +V+     + L  +L  +Q +I+         VK          N    ++N     +D+E   + +             D F  + DV  + +SSGTTG PKGV +T   VV+            FLD    T   + + L      HI G   + F T H          F   TF                    +  +  DVK  H   ++            L E   +  P+      +G TE S    +   N+    S G  VA T   + DL TG+ L P K GE+   K      GYL      E    K+GW HTGD  +Y +   F+   R+ E+IK  G  V P ELE  +++ H  +++V V+ +  EK+  V  A +V++ ++ +  E I + +N++V +YKR+ G +   +  +P++A GK+LR ++
Sbjct:   64 RVENIAAALYQIGARNGDVLGLFLPNHIDYPL-VHTGATSLGMITTTVNPTYKPSELSRQLIMSQTKILVTMKAFLPTVKEALAKIEGDQNVAVVVLNTTDHQSDVELSFDKLLQESHGGAFTTNYDSFDFENDVVSLPFSSGTTGVPKGVMLTHQNVVNNARQMIYSQDFNFLD--LPTDSFQPSTLCVLPLFHIFGLNVTTFPTLHVGGKLVMLPSFDPKTFLEALEQYRPTFMHFAPPLVGFCANHPDVKPHHLESIESVFVGAAPVGKALSESFLRKAPHIAFREGFGMTELSPCATMTPGNRVVGGSCGTPVANTAMKVVDLTTGEDLPPLKQGEICV-KGPQVMKGYLRNDIATESTI-KNGWLHTGDIGYYDDNKFFYVVDRLKELIKVSGYQVPPAELENTIRS-HPAVLDVAVIGIPDEKRGEVPRAYVVLRPNQNVTEEVIHEFVNEEVADYKRLLGGIEFMQV-IPKSASGKILRKDL 545