Query:   20 VAKHLVAIRDIPPGKAIFSETPLAQGPSPDHPNDDDICIVCLSELDHAMVCSKCFWPVCSSECGRSDQHKMECATLAACARESEEDLLPLRHLVVMRCLLMKHRDQYAWEKLMDLEDHHGVQTLIRNVEEELSDMDRLELKYFIRESCGMGIKTD---LDIVADIVQSSSIQVDCESLEPFPAMYLTGGLLSQACVPNTVLRFDEDKDFLMTVYSARKISKGEKITFCPLQH-LTKSGTRERRKKLMRRLINCFCDRCVDPEECGSFSSAFICQKCAPKGTEDRGLILPINPVEEESPWQCQKCNYSMTSDTVESLLSRLRDSLEATKCEDNEVKFRDFILSNRSILHPNHYLMIACKDGLFNLKTSEASRAIDISIADKLETVEMGLDLLKVADILEPGLTSTRGKLLFTLGTTLQEMLSQEVMNRMESPEHAELDERHIYSAFHDALFCFEEAKKI 473
            V  HLV+  D+ PG  IF E P+A  PS                       S C+WP+CS  CG+S  HK EC +L AC    ++++LP +HL+V+RCLL++  D+  WEKL+ LEDHHG+QTLI++ +EE SD    EL  FIR+ CG+G   D   ++ V DIV+S  I V C  ++ FPA+YLT GL+S +C  NT L F  D +F ++V +   I  G K+T C LQ  +   GT ERR  L   LI+C+C RC+D  ECGSFSSA +C  C    +     +L  NP++E++ WQC  C+ + +SD V SL    +D LE         + R+F++SN+ +LHP+H+LMI+CK  +F+    E   +   +I D +E V++G +L+ VA+IL PG+T +RGKLL  LG   Q ++S+E+MNR+E  E   L E+ +++ F D+ +C++E   I
Sbjct:    4 VLLHLVSTCDLMPGDVIFFEKPIAFSPS-----------------------SSCWWPLCSFXCGQSXXHKAECQSLXACVGRPDDEMLPFQHLLVLRCLLLRLNDKEXWEKLLSLEDHHGIQTLIQSDQEEESDSSLNELLLFIRDDCGIGNVMDDETIETVFDIVRSCLIHVKC--VKKFPALYLTAGLISHSCFENTRLVFHPD-NFGVSVIACLPIKAGTKLTRCYLQKDVIFLGTEERRTFLEDYLIDCYCIRCMDSTECGSFSSAILCPTCDKLNSP----VLSSNPLDEDTEWQCAVCSSTFSSDFVRSLCLSSKDQLENAY---QTPELRNFLISNQFVLHPHHFLMISCKAKIFHCLGRENESS---TIGDLIEKVKLGKELMAVAEILIPGITVSRGKLLLKLGNAFQLLVSRELMNRIECREELGLSEKQVFNTFFDSNYCYQEVLHI 425          

Query:   20 VAKHLVAIRDIPPGKAIFSETPLAQGPSPDHPNDDDICIVCLSELDH---AMVCSKCFWPVCSSECGRSDQH-KMECATLAACARESEEDLLPLRHLV-----VMRCLLMKHRDQYAWEKLMDLEDHHGVQTLIRNVEEELSDMDRLELKYFIRESCGMGIKTDLDIVADIVQSSSIQVDCESLEPFP----AMYLTGGLLSQACVPNTVLRFDEDKDFLMTVYSARKISKGEKITFCPLQHLTKSGTRERRKKL-MRRLINCFCDRCVDPEECGSFSSAFICQKCAPKGTEDRGLILPINPVEEESPWQCQKCNYSMTSDTVESLLSRLRDSLEATKCEDNEVKFRDFILSNRSILHPNHYLMIACKDGLFNLKTSEASRAIDISIADKLETVEMGLDLLKVADILEPGLTSTRGKLLFTLGTT----LQEMLSQEVMNRMESPEHAELDERHIYSAFHDALFCFE 468
            + ++LVA  DI  G  IF+E PL  GP         +C+ C +EL        C +C WP+CS  C  S  H   EC+ L+    +   D     +++     V+R L +K  + + W++ +  + H   +   +  ++   +     + YF++    +   +DL+I+        +  +C  +  F      +Y  G ++S  C PNT   F+E+ D  + VYS   I KGE I     Q L    T  RR+ L M +   C C RC DP E G++ SAF C +C        G +LP++P++++S W+C+KC++++ S TV   +  + D L++     N     DF+    ++L   + L    + GL +L  +   R  D+     L    M   LL VA+ ++PG +  RG+LL  + +      Q  L++  ++ +++ +  + + +H+  A  D + C E
Sbjct:  189 LGRYLVAKDDISEGSLIFNEPPLVIGP---RQLTKAVCLXCHNELKDKKDTYPCRRCTWPMCSRSCSDSPVHANAECSILSYGGVKVNIDAFGTANMMYACITVLRALSLK--NDHKWQEYLKFDSHLNERMPTQVYQQVNKEKVVFFIHYFLK---LLSKFSDLEILE---ACGKLDTNCFEIRQFGKNLRGLYRIGSIMSHECTPNTRHTFEENYD--INVYSTVDIKKGEIICATYTQPLW--CTLSRREHLNMSKCFWCRCKRCSDPTEFGTYLSAFSCSECG-------GKMLPLDPLDQKSNWKCEKCSHTLESTTVRHGIESMMDELKSID-RTNPENLEDFLKRYATLLPETNQLTREIQLGLVSLFKNR--RNEDLKTTQLLRKAFMCRQLLTVANRVDPGFSKWRGELLLEMQSANVILGQRALAEGRISNIQAKDIFDENMKHLKEA--DRVLCIE 628          

Query:   24 LVAIRDIPPGKAIFSETPLAQGPSPDHPNDDDICIVCLSELDHAMVCSKCFWPVCSS-ECGRSDQH-KMECATLAAC-------ARESEEDLLPLRHLVVMRCLLMKHRDQYAWEKLMDLEDHHGVQTLIRNVEEELSDMDRLELKYFIRESCGMGIKT-DLDIVADIVQSSSIQVDCESLEPFPAMYLTGGLLSQACVPNTVLRFDEDKDFLMTVYSARKISKGEKITFCPLQHLTKSGTRERRKKLMR-RLINCFCDRCVDPEECGSFSSAFICQKCAPKGTED-RGLILPINPVEEESPWQCQKCNYSMTSDTVESLLSRLRDSLEATKCEDNEVKFRDFILSNR--SILHPNHYLMIACKDGLFNLKTSEASRAIDISIADKLETVEMGLDLLKVADILEPGLTSTRGKLLFTLGTTLQEMLSQEVMNRMESPEHAELDERHIYSAFHDALFCFEEAKKIQRLNKTN 480
            L+  RDI PG+ IF E+P+  GP         +C+ C   ++   +CS C WP+C + EC ++  H K ECA LA C         + E+DL   + L  +RCLL+K      W  L  +E H    T +R  EE    ++++ +  FI E         D++   D++  ++ ++          +Y    +++  C PNT    DE+  ++  V +  +I KG +I     + L  SGT  RR +L   +  +C C+RC DP E  S  S  +CQ   P  ++  +G +   N +   + W C+ C   M+ + V  L  +L   +E      ++  + +F L NR    LHPNHY+++  K  L     S A    +I I  ++    +  D+L V  ++ PG    R  L+      +  +    + N  ++    E  ER I     D L   EE   I R   TN
Sbjct:   81 LIVTRDIEPGEVIFEESPITVGPKQFC---QPVCLGCYKNVNGTSICSGCNWPMCGNIECEKAPIHSKKECALLADCHLKPIIDLNKPEKDLPIYQFLTALRCLLVKEFRPDNWSILESMESH----TELRKNEESYR-VNQVNIVKFILERIKYDTTVEDINKCIDVMDVNAFEIRSHEFS-IAGLYPMTAMMNSNCSPNTQNSIDEN--YICRVMAITRIPKGSEINSTYTRTL--SGTLYRRNQLKESKYFDCKCERCCDPTELNSHFSTLLCQAILPSISKTCKGFVYSENSLNTNASWICRACGAVMSHEEVTELTQKLEVEIEKEFLTIDD--YENF-LKNRLLKFLHPNHYIIVDFKFILMK-ALSRAEYDPEIRIQREIRKKRIIEDILDVHSLITPGYFRIRAMLVSERCMVMMSIAFHNLSNSNKNEIFLEECERII-----DGL---EECVSILRFENTN 526          

Query:    5 FPALREASTKRMASSVAKHLVAIRDIPPGKAIFSETPLAQGP-SPDHPNDDDICIVCLSELDHAMVCSKCFWPVCSSECGRSDQHKMECATLAA--CARESEEDLLPLRHLVVMRCLLMKHRDQYAWEKLMDLEDHHGVQTLIRNVEEELSDMDRLELKYFIRESCG--------MGIKTDLDI-----VADIVQSSSIQVDCESLE---PFPAMYLTGGLLSQACVPNTVLRFDEDKDFLMTVYSARKISKGEKITFCPLQHLTKSGTRERRKKLMRRLINCFCDRCVDPEECGSFSSAFICQKCAPKGTEDRGLILPINPVEEESPWQCQKC----NYSMTSDTVESLLSRLRDSLEATKCEDNEVKFRDFILSNRSILHPNHYLMIACKDGLFNLKTSEASRAIDISIADKLETVEMGLDLLKVADILEPGLTSTRGKLLFTLGTTLQEMLSQEVMNRMESPEHAELDERHIYSAFHDALFCFEEAKK 472
            FP + + S +       +++VA RDI P + I SE P   GP S   P     C+ C   +D +  CSKC  PVC  EC   D H+ EC          + E        +  +R LLMK  D   + K+  L DH   + +I     +  ++  L +  F++E           +    D D      +  I++++ ++ +    E   P  A+Y    L++ AC  NT   + +  DF + + S   I KGE+I F      T    R R+        +C C RC+D  E G++ S   C+ C        G +LPIN +  ES W C  C    NY   SD ++++ S++R S+E    ++ E    + +   + +LHPNHY++I   D + NL    A++   ++  +K   +++ + +L+    ++PG T  R       GT LQEM+   +M   E  E+  + ER  +   +       EAKK
Sbjct:  108 FPFIVKRSKR-----FGRYMVAARDINPLELILSEQPAVVGPYSKKLPG----CLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKENHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVI----NKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNT--NYVKFPDFHLELRSQIPIKKGEQI-FTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCK------NGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVR-SIEHETIDELE----EMLYHYQKLLHPNHYIVI---DIMHNLIHVYAAKET-LTRPEKERKIQLCMSVLETLGRVDPGYTKWR-------GTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKK 560          

Query:   18 SSVAKHLVAIRDIPPGKAIFSETPLAQGPSPDHPNDDDICIVCLSELDHA-MVCSKCFWPVCSSECGRSDQHKMECATLAACARESEEDLLPLRHLVV-MRCLLMKHRDQYAWEKLM-DLEDHHG----------------VQTLIRNVEEELSDMDRLELKYFIRESCGMGIKTDLDIVADIVQSSSIQVDCESLEPFPAMYLTGGLLSQACVPNTVLRFDEDKDFLMTVYSARKISKGEKITFCPLQHLTKSGTRERRKKLMRR-LINCFCDRCVDPEECGSFSSAFICQKCAPKGTEDRGLILPINPVEEESPWQCQKCNYSMTSDTVESLLSRLRDSL-EATKCEDNEVKFRDFILSNRSILHPNHYLMIACK----DGLFNLKTSEASRAIDISIADKLETVEMGLDLLKVADILEPGLTSTRGKLLFTLGTT 430
            S + +HLVA RDI   + I  E+PL  GP   + + ++ C+ C   LD +   C  C +P CS EC +   HK+EC+       + +E+      ++  +R L ++      W  +M D+ DH+                 V   I+++ +  +D D L     + ++ G     DL++  D                   +YL    L+ +CV NT     +D+   M   ++  ISKGE+I  C         T  RR  +  +   +C C RC DP ECGS+  A +C  C       + ++LPINP+E ES W C+ C+     + V  +L  + +SL EAT  + N   +   +   + +LHPNHYL I  +      + N+ TS  S+ +     ++    +    +L+V  +++PG    R ++L  L  T
Sbjct:   56 SQLGRHLVATRDIKALEVILEESPLVIGP---YISSNNQCLECFKTLDTSPHSCISCNYPFCSQECSQGPWHKIECSAFQKYGHKRDENDNDFYSIITTLRLLSLQESKPEFWNTIMKDMLDHNSDIQEYTPEKWTSYEETVVKKIQSLTKGNADTDTLTRLIGVIDTNG----ADLNLPHDGKHGKGT-----------GLYLIYSNLNHSCVCNTKTINFQDRRIEMR--ASVNISKGEQI--CNQYVRPNKCTLARRTTIKNKWYFDCCCKRCADPTECGSYLGALLCSSC-------KSVVLPINPLETESNWACKGCSKEYDVEYVMGVLISVGESLEEATPYDPNS--YEKILYDTQDLLHPNHYLRIEAELKVAALIGNIPTSSFSKGMPRPAVERKR--QCCFHILEVLSLVDPGFNQWRVQILSELTKT 460          

Query:   20 VAKHLVAIRDIPPGKAIFSETPLAQGPSPDHPNDDDICIVCLSELDHAMVCSKCFWPVCSSECGRSDQHKMECATLAACARESEEDL-------LPLRHLV-VMRCLLMKHRDQYAWEKLMDLEDHHGVQTLIRNVEEELSDMDRLELKYFIRE--SCGMGIKTDLDIVA----DIVQSSSIQVDCESLEPFPAMYLTGGLLSQACVPNTVLRFDEDKDFLMTVYSARKISKGEKITFCPLQHLTKSGTRERRKKLMR-RLINCFCDRCVDPEECGSFSSAFICQKCAPKGTEDRGLILPINPVEEESPWQCQKCNYSMTSDTVESLLSRLRDSLEATKCEDNEVKFRDFILSNRSILHPNHYLMIACKDGLFNL----KTSEASRAIDISIADKLETVEMGLDLLKVADILEPGLTSTRGKLLFTLGTTLQEMLSQEVMNRMESPEH 448
            + ++L A RD+ PG+ I  E P    P    P    +C+ C + +D   +C  C WP+C+  C  S  H  EC   A   R S   +        PL  +V ++RCL MK +    ++ L+ LE H   +  I+N +      D++ +   IRE  S       D DI+A      V S  + V   ++ P  A+Y    LL  +CV N    FD + + L+ V  A  I KGE I+   +      GT  R++ L+  +   C C RC DP E  +  S+  C  C        G ++ ++P   ES W+C+ CN   T   V +++  + + L + +    E     F+  +   LHP+H+ ++  K  L  +         S   ++   D L+  ++  ++L+VA+ + PG++  RG +++ L         ++  N   S +H
Sbjct:   57 LGRYLXATRDLKPGELILMEAPTIIAPMAVTP---PVCLSCYAPVDGRYMCPLCGWPMCNEICRNSPAHIPECRITA--ERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPH--TKERIKNGK---YSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPV---TMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRV--AIPIKKGEHISI--MYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPA------GFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACL-SFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDH 480          

Query:   19 SVAKHLVAIRDIPPGKAIFSETPLAQGP-SPDHPNDDDICIVCLSEL--DHAMVCSKCFWPVCSSECGRSDQHK-MECATLAACA-RESEEDLLP--------LRHLVVMRCLLMKHRDQYAWEKL---MDLEDHHGVQTLIRNVEEELSDMDRLELKYFIRESCGMGIKTDLDIVADIVQSSSIQVDCESLEPFPAMYLTGGLLSQACVPNTVLRFD-EDKDFLMTVYSARKISKGEKITFC---PLQHLTKSGTRERRKKLMR--RLINCFCDRCVDPEECGSFSSAFICQKCAPKGTEDRGLILPINPVEEESPWQCQKCNYSMTSDTVESLLSRLRDSLEATKCEDNEVKFRDFILSNRSILHPNHYLMIACKDGLFNLKTS-EASRAIDISIADKLETVEMGLDLLKVADILEPGLTSTRGKLLFTL 427
            SV +++VA RDI PG+ +  E PL  GP +P+ P    IC+ C + +  +    C  C +P+CS EC +  +HK  ECA +     R   ++ L            + +MR L++K RD   W  +   M  ++     T  +  + +  +  +  +K    +   + I   + +V D      ++   E       ++    + + +CV N    F   ++ F MT+ +   I +G++IT     PL  +       RR+ L++  +   C C RC DP E  ++SSA IC KC       +G ++  N     S W+C  C+ +++ D+VE + S+ +  +E      +      F+    +I HPNH  MI     L  +    E      +S    +   E+   +LKV +++ PG T  +G +++ L
Sbjct:   38 SVGRYMVATRDIKPGETVLMEYPLTFGPGNPNEP----ICLGCYTPVLKNQHTECDGCGFPMCSKECSQILEHKDFECAEMHNMNFRLDSQNTLKWNGSQESVYNAISLMRALVLKKRDPARWNLIWMHMSHDEARQKDTFWQKKDAKTLEHIKAMMKISPEDYDTIKIILGIFLVNDFEICIPLEGSDEKSSLIRGIFALASMPNHSCVSNCYHNFTCREEGFKMTMKAVVDIKEGDEITHSYTEPLDPIM------RRQSLLKIGKFFQCNCIRCRDPTEMSTYSSALICSKCK------KGNVISKNCKNINSDWECDSCDLTLSPDSVEQVNSKAKSEIEEMDKNPDVETHEQFLNKYATIFHPNHVYMIDRSYVLGKMYGRMEGYEPDSLSDDQFMRKKELCERVLKVLNVITPGQTRKKGMMMYEL 453          

Query:   18 SSVAKHLVAIRDIPPGKAIFSETPLAQGPSPDHPNDDDICIVCLSELDHAM-VC-SKCFWPVCSSECGRSDQHKMECATLAACARESEEDLLPLRHLVVMRCLLMKHRDQYAWEKLMDLEDH----HGVQTLIRNVEEELSDMDRLELKYFIRESCGMGIKTDLDIVAD----------IVQSSSIQVDCESL-------EPFPAMYLTGGLLSQACVPNTVLRFDEDKDFLMTVYSARKISKGEKITFCPLQHLTKSGTRERRKKLMR--RLINCFCDRCVDPEECGSFSSAFICQKCAPKGTEDRGLILPINPVEEESPWQCQKCNYSMTS-DTVESLLSRLRDSLEATKCEDNEVKFRDFILSNRSILHPNHYLMIACKDGLFNLKTSEASRAIDISIAD------KLETVEMGLDLLKVADILEPGLTSTRGKLLFTLGTTLQEMLSQ--EVMNRMESPEHAELDERHIYSAFHDALFCFEEAKKIQRLNK 478
            S++ + L   RD+  G  I S  P   GP  D+P     C+ C   LD  M +C   C +P+CSSEC R    + EC  L       +        + ++R  L+K  +   +EKL+ LEDH        T  +N+EE +       LK+         IK+DLDI  D          I  S  ++   + L       E    +Y    L++ +CV N   R   +    + VY+A  IS    ITF    +++     +RR+K+++  +   C C+RC DP E G+FSS+ +CQ C            P    ++   ++C+ C+  M+  D ++   S ++   +  +     V    F+   + IL   H  +I  K  L  L  S  +    IS  D      ++E      D+L V DI++PG++  RG +L  L      + +   E MN  +  E ++ D+  +  + +DAL    E++K  + NK
Sbjct:   56 SALGRQLRTARDVKQGDLIISAPPCVIGPRLDYPKPS--CLGCHVILDEKMSLCEGGCEYPLCSSECHRKFHSEEECKLLEKIKSPDKR----CEIVTILRFALLKKSNPRIYEKLILLEDHVDEIKASSTRWKNIEEGV-------LKHLKE------IKSDLDIEEDQELERLVGIWITNSFELERTDQQLFGEKRAGESIQGLYDVPSLMNHSCVGNA--RLVINSGMYIDVYAAVPISNKAPITF---NYISPLEDYDRRQKILKENKFFECKCERCEDPTELGTFSSSLLCQVCKKS---------PSTRTKDSKNYECRDCSEVMSERDAMKIANSLMKGKNKLHRIGKAWVTCIPFLKEYQDILWETHTFIIXIKMXLVXLXXSNXA----ISQMDENGKKIQIERQSYCNDVLAVQDIIDPGMSLGRGLVLHELHAARVFLANYRFENMNAEKEEEPSQEDKMELLMSLYDALENLXESRK--KFNK 511          

Query:  115 MRCLLMKHRDQYAWEKLMDLEDHHGVQTLIRNVEEELSDMDRLELKY--FIRESCGMGIKTDLDIVADIVQSSSIQVDCESLEPFPAMYLTGGLLSQACVPNTVLRFDEDKDFLMTVYSARKISKGEKIT--FCPLQHLTKSGTRERRKKLMRRLINCFCDRCVDPEECGSFSSAFICQKCAPKGTEDRGLILPINPVEEESPWQCQKCNYSMTSDTVESLLSRLRDSLEATKCEDN-EVKFRDFILSNRSILHPNHYLMIACKDGLFNLKTSEASRAIDISIADKLETVE-------MGLDLLKVADILEPGLTSTRGKLLFTLGTTLQEMLSQEVMNRMESPEHAELDERHIYSAFHDALFCFEE 469
            +R L +K ++   W ++  L DH         V++   DM  L  K   FI +SC +   T  DI+  +    +  V+    + F  +Y T   +S +C PN   RF   ++  + + + + I KGE+IT  + P+   T    R R K     L +C+C+RC DP E GS  SA  C++C        G++LP    + +S W+C +C Y ++  ++ +++     ++E     D  E++F+  I S    L+PN+YL+      L ++          +   D  ET E       +  D+LK+ D++EPGL++TRG++L  +     ++   ++ +   + +   L  + I      A+ C EE
Sbjct:  305 LRILKLKSKEPEVWSRVNLLMDH---------VDDLEKDMKSLYEKTVDFILDSCKLTKYTRSDILRALGIFRTNGVNQGFSQGF-GLYPTFSFISHSCSPNA--RFQIFENHSLVLRAIQNIPKGEEITISYLPIYQAT---FRRRIKIKNNWLFDCYCERCKDPSEFGSNLSAVSCKECI------TGILLPKISTDMKSEWKCSECKYEVSFSSLSNVMLVFEQNMELFLDHDPLEIQFK--IDSWTQTLNPNNYLIFLLNRRLLDV----------LCTNDNFETREDLEKVLLLARDILKIVDLIEPGLSTTRGRILKQIHKPSLKLAKNDLKDGKINSQEFLLITKDIIKNMKTAVRCLEE 638          

Query:   55 DICIVCLS-------ELDHAMVCSKCFWPVCSSECGRS--DQHKMECATLAACARESEEDL-------LPLRHLVVMRCLLMKHRDQYAWEKLMDLEDHHGVQTLIRNVEEELSDMDRLELKYFIRESCGMGIKTDLDIVADIVQSSSIQVDCESLE-PFP-------AMYLTGGLLSQACVPNTVLRFDEDKDFLMTVYSARKISKGEKITFCPLQHLTKSGTRERRKKLM-RRLINCFCDRCVDPEECGSFSSAFICQKCAPKGTEDRGLILPINPVEE--ESPWQCQKCNYSMTSDTVESLLSRLRDSLEATKC-EDNEVKFRDFILSNRSILHPNHYLMIACK-DGLFNLKTSEASRAIDISIADKLETVEMGLDLLKVADILEPGLTSTRGKLLFTLGTTLQE 433
            D  IVCL+       E +   VCS+C  P+C  +C  S  + HK EC  L++  R     L       L    ++V+RCL ++   +  W   + L  H G +   R+ E E   ++  E    IR+   +GI+   + V +I       +D  S E P P       A+Y  G L    C+P     F+ D   ++   ++  +  G+ IT      L    T ERR  L+  +  +C C+RC DP E GSF  A  C KC        G ILP NP+E+  E+ W C  C Y       E   +++   ++  +  E N  +   FI     IL+  H  M+  K   L  L   E     D+S        ++   LL+VA+ + PG++  RG  L+ L  T Q+
Sbjct:  436 DSSIVCLNCYGSIQDENEDISVCSRCGLPLCG-QCDESELNLHKPECHALSSSKRGKRTSLALLDNVSLLFEVVLVLRCLHLRDIPE-NWSHFLGLTSHVGER---RDSELEARALEASEXX--IRD---IGIEIPREEVLNICGI----LDTNSFEIPLPSSPGTIQAIYKIGCLPEHNCIPTGHRCFESDLSLVLR--ASVDLKAGDHITITYTDSLWP--TMERRTHLLYSKHFSCICERCRDPTEKGSFIGALNCLKCG------VGRILPENPLEDKNETSWICIDCGYVSPQGFAEDTYNQVAQVIQGMESGEINPEQCNRFITLYSKILNSQHAHMLDVKHTLLHLLGHHEGYLLGDLSNYLLQLKEDIARCLLQVAEKILPGISRLRGTTLYELYLTYQQ 819          

Query:   10 EASTKRMASS--VAKHLVAIRDIPPGKAIFSETPLAQGPSPDHPNDDDICIVCL----SELDHAMVC-SKCFWPVCSSECGRSDQHKMECATLAACARESEEDLLP--LRHLVVMRCLLMKHRDQ---YAWEKLMDLEDHHGVQTLIRNVEEELSDMDRLELKYFIRESCGMGIKTDLDIVADIVQSSSIQVDCESLEPFPAMYLTGGLLSQACVPNTVLRFDEDKDFLMTVYSARKISKGEKITFCPLQHLTKSGTRERRKKLMRRLINCFCDRCVDPEECGSFSSAFIC--QKCAPKGTEDRGLILPINPVEEESPWQCQKC 319
            E  + R+A S    + + A R+I  G+ +F E  L  GP+     +   C +C        D A +C + C  PVCS EC  S +H +EC           + + P  LR L V+RC  +    +   YA +  MD      VQ      E    + D L+  YF R  C            +  +S S     E L    A++   GLL+  C PN    F+  +   + V +  +I  G +IT    + L  +  R+    + +  I C C RC DP E G++ SA  C  Q C       RGL++P+     +  W+C  C
Sbjct:   40 EEPSWRVADSPISGRGIFATREIAAGEELFREHTLLVGPTAHRSMNLRTCTLCYRLIPGSTDSAALCPAGCGLPVCS-ECRDSTRHDLECKLFRKWKPLESQRIEPRALRILSVVRCFFLDEASRKLLYAMQANMDRYYMQEVQRAADCFEHFPREQDMLD--YFYRTICAFN--------TNAFESRSNVDGHEVL--VRALFPLAGLLNHQCTPNAAHHFENGET--IVVCATERIPAGAEITMSYAKLLWSTLARKIFLGMTKHFI-CKCVRCQDPTENGTYLSALFCREQGC-------RGLVIPVQTRTLQPDWRCITC 340          

Query:   24 LVAIRDIPPGKAIFSETPLAQGPSPDHPNDDDICIVCLSELDHAMVCSKC-FWPVCSSECGRS--DQHKMECATLAACARESEEDLLPLRHLVVMRCLLMKHRDQYAWEKLMDLEDHHGVQTLIRNVEEELSDMDRLELKYFIRE----SCGMGIKTDL-DIVADIVQSSSIQVDCESLEPFPAMYLTGGLLSQACVPNTVLRFDEDKDFLMTVYSARKISKGEKITFCPLQHLTKSGTRERRKKLMRRL-INCFCDRC 273
            L A+  + PG+ +F   PLA        +   +C  CL   +  M CS+C     CS++C +     HK EC  L +C      D + L   VV + +     +        DLE +  +  L  + +E L  +  +  ++F+RE    +  +    DL +  A ++ +S    + E  E    +Y +  LL+ +C PN  + F+     L  V   R I  GE++T C L  L  S   ERRK+L  +    C C RC
Sbjct:   18 LRAVTPLRPGELLFRSDPLAYTVCKG--SRGVVCDRCLLGKEKLMRCSQCRVAKYCSAKCQKKAWPDHKRECKCLKSCKPRYPPDSVRLLGRVVFKLMDGAPSESEKLYSFYDLESN--INKLTEDKKEGLRQL-VMTFQHFMREEIQDASQLPPAFDLFEAFAKVICNSFTICNAEMQEVGVGLYPSISLLNHSCDPNCSIVFNGPHLLLRAV---RDIEVGEELTICYLDMLMTS--EERRKQLRDQYCFECDCFRC 266          

Query:   21 AKHLVAIRDIPPGKAIFSETPLAQGPSPDHPNDDDICIVCLSELDHAMVCSKCFWPVCSSECGRSDQHKMECATLAACARESEEDLLPLRHLVVMRCLLMKHRDQYAWEKLMDLEDHHGVQTLIRNVEEELSDMDRLELKYFIRESCGMGIKT-DLDIVADIVQSSSIQVDCESLEPFPAMYLTGGLLSQACVPNT--VLRFDEDKDFLMTVYSARKISKGEKITFCPLQHLTKSGTRERRKKLMRRLINCFCDRCVDPEECGSFSSAFICQKCAPKGTEDRGLILPINPVEEESPWQCQKCNYSMTSDTVESLLSRLRDSLEATKCEDNEVKFRDFILSNRSILHPNHYLMIACKDGLFNLKTSEASRAIDISIADKLETVEMGLDLLKVADILEPGLTSTRGKLLFTLGTTLQEMLSQEVMNRMESPEHAE-LDERHIYSAFHDALFCFEEAKKIQRLNKTNQGKEVYSTIKSSMHVLRDMKKDFE 504
            ++HLVA+RD+  G+ IFSE P+A GP     +    CIVC    D   VCS+C+W +C   C  SD H+ EC  L++C  +  E  LP RH++ +RC+L+K ++   WEKL  L DH G+Q+L  + +    D    +L  FIR+ CG+     D+  V     SS I    E +     +YL GGLL+ +C+ NT  +++ D+ K   M VY++  I KGEKIT+C L  +   GT ERR+ L    ++C C RC DP EC S++S+  CQ+C        G+ +P+NP+ ++  W+C  C  ++    V +LL  +R+ ++  +   ++ ++R F   N+ ILHPNHYL  A +   F         +++ S+ D L  +  G D+L++ D+L+PGL+  R  LL  LGT LQ +LS E++ R  S  + E L +  +Y+ F DALFCF+EA+K   L      K   ++I  ++ +L +M++ FE
Sbjct:   18 SRHLVALRDLEAGELIFSEHPVAVGPGDSQGS----CIVC--SRDTQAVCSRCWWTLCQ-RCVHSDIHQEECRLLSSCTVKGPELGLPTRHVLSLRCILLK-KNLRIWEKLQGLCDH-GLQSLDLSPDILNQDPGLRDLVSFIRDDCGLNYSIEDISSVYLAATSSCIIARSEGIS-LHGVYLQGGLLTHSCIQNTRIIIKGDQPK---MFVYASVPIKKGEKITYCRLPEVVPIGTLERRRLLRESFLDCHCKRCCDPTECSSYTSSIYCQRC-------EGVCIPLNPLNQDCTWKCLSCQETVDGRFVSTLLLSIREDIKTFQGSRSQ-RYRTFREQNKRILHPNHYLHTAERAKFF------LQFSVEESVEDTLLKISAGKDMLELVDVLDPGLSIFRESLLVNLGTNLQLLLSDEIVRRQSSDTNTENLADTQVYAGFRDALFCFKEARKAAELEGC---KSAMTSIDENISILEEMRQYFE 475          

Query:    2 WNKFPALREASTKRMASSVAKHLVAIRDIPPGKAIFSETPLAQGPSPDHPNDDDICIVCLSELDHAMVCSKCFWPVCSS-ECGRSDQ-HKMECATLAACARESEEDL--LPLRHLVVMRCLLMKHRDQYAWEKLMDLEDHHGVQTLIRNVEEELSDMDRLELKYFIRESCGMGIKTDLDI-VADIVQSSSIQ---VDCESLEPFPAMYLTGGLLSQACVPNTVLRFDEDKDFLMTVYSARKISKGEKITFCPLQHLTKSGTRERRKKLMR-RLINCFCDRCVDPEECGSFSSAFICQKCAPKGTEDRGLILPINPVEEESPWQCQKCNYSMTSDTVESLLSRLRDSLEATK---CEDNEVKFRDFILSNRSILHPNHYLMIACKDGLFNLKTS-EASRAIDISIADKLETVEMGLDLLKVADILEPGLTSTRGKLLFTLGTTL 431
            W K  +   A       +V + L+A RD+  G  I  E PL  GP         +C+ C S +D    CS+C WP C   EC  +D  H +EC  +A+  R     L     + ++V+RCL +K ++   WE+L+ LE H     +    +  L D+D+      IRE+ G+ +  +L + +  I+  +S +   +   S +   A+Y T  LL   CV N +  F  + D +  + +A  ISKG+KI  C  + L   GT  R++ L + +   C C+RC DP E  +F S   CQKC     +  G++L  NP ++ S W+C++C     ++ V  ++  +   + A K    +D EV  R F      ILHPNH+ +   K  L  +    E    I+++    +    + L+LLKVAD + PGLT  R  LL+ L   L
Sbjct:   43 WKKHRSNCRAYRVERTLNVGRRLIACRDLKAGDVILQEKPLVMGPKY---TAGQVCLGCYSSVDGRTKCSQCGWPTCGRVECHTNDSDHAVECGLIASGGRPIVGSLPVQAYQSVMVLRCLALKDQNPGRWEELLQLESH-----VHERRQRGLEDVDQATSVRLIRETLGLDVPEELILQLCGILMVNSFEQPPLKANSPQGLVAVYSTASLLEHDCVANAIKTFTNNGDIV--IRAAVPISKGDKIALCYTEPLW--GTVNRQRHLSQTKFFQCVCERCKDPTELDTFISGLYCQKCP----QQSGILLIENPTDDASDWKCRQCGTRQPANYVAEIIESVGKEIVALKKGSLKDCEVFLRKF----SKILHPNHFYLTDVKMALCQMYGHLEGQSLIEMNDDTLIAKEALALELLKVADAVSPGLTRLRAILLYELQAVL 465          

Query:    2 WNKFPALREASTKRMASSVAKHLVAIRDIPPGKAIFSETPLAQGPSPDHPNDDDICIVCLSELDHAMVCSKCFWPVCSSECGRSD------QHKMECATLAACARESEEDL--LPLRHLVVMRCLLMKHRDQYAWEKLMDLEDHHGVQTLIRNVEEELSDMDRLELKYFIRESCGMGIKTDLDI-VADIVQSSSIQ---VDCESLEPFPAMYLTGGLLSQACVPNTVLRFDEDKDFLMTVYSARKISKGEKITFCPLQHLTKSGTRERRKKLMR-RLINCFCDRCVDPEECGSFSSAFICQKCAPKGTEDRGLILPINPVEEESPWQCQKCNYSMTSDTVESLLSRLRDSLEATK---CEDNEVKFRDFILSNRSILHPNHYLMIACKDGLFNLKTSEASRAIDISIADKLETVE-MGLDLLKVADILEPGLTSTRGKLLFTLGTTL 431
            W K  +  +A       +V +HL+A RD+  G  I  E P+  GP         IC+ C S +D    CS+C WP+C    GR D       H  EC  +A+  R     L     + ++V+RCL ++ ++   W++LM LE H  VQ      ++ + D+D+     FIRE+ G+ I  +L + +  I+  +S +   +   S     A+Y T  LL   CV N +  F    D +  + +A  I KGEKI  C  + L   GT  R++ L + +   C C+RC DP E  +F+S F CQKC  +     G++L  NP+++ S W C++C     ++    ++  +   + A K     D E   R F      +LHPNH+ +   K  L  +      +++     D L   E + L+LLKVAD + PG+T  R  LL+ L   L
Sbjct:   34 WKKHRSHCKAYRIEQTLTVGRHLIACRDLKAGDVILQEKPIVMGPKH---TAGQICLGCYSGVDGRTRCSQCGWPMC----GRDDCHAHESDHAAECGVMASGGRPIVGSLPVQAYQSVMVLRCLALRDQNPERWDELMQLEAH--VQ---ERRQKGMEDVDQATAVRFIRETLGLQIPEELILQLCGILMVNSFEQPPMKGNSQHGLVAVYSTASLLEHDCVANAIKTFTNKGDIV--IRAAVPIPKGEKIALCYTEPLW--GTMNRQRHLSQTKFFQCVCERCKDPTELDTFTSGFYCQKCPQQSA---GILLTENPLDDASDWICRQCGARQPANYAAEIIESVGKEIVALKKGSVRDCEGFLRKF----SKVLHPNHFYLTDVKMALCQMYGHLEGQSLIEMNDDTLNAKEALALELLKVADAVSPGMTRLRAILLYELQAVL 457          

Query:   20 VAKHLVAIRDIPPGKAIFSETPLAQGPSPDHPNDDDICIVCLSELDHAMVCSKCFWPVCSSECGRSDQHKMECATLAACARESE----------EDL-LPLRHLVVMRCLLMKHRDQYAWEKLMDLEDHHGVQTLIRNVEEELSDMDRLELKYFIRESCGMGIKTDLDI--VADIVQSSSIQVDCESLEPFPAMYLTGGLLSQACVPNTVLRFDEDKDFLMTVYSARKISKGEKITFCPLQHLTKSGTRERRKKLM-RRLINCFCDRCVDPEECGSFSSAFICQKCAPKGTEDRGLILPINPVEEESPWQC---------QKC-NYSMTSDTVESLLSRLRDSLEATKCEDNEVKFRDFILSNRSILHPNHYLMIACKDGLFNLKTSEASRAIDISIADKL-ETVEMGLDLLKVADILEPGLTSTRGKLLFTLGTTLQEMLSQEVMNRMESPEHAELDERHIYSAFHDALFCFEEAKKI 473
            + +++VA R   PG+ I SETPL  GP          C   L++ D    C  C WP+CS +C    Q+     +     +E++          +DL + L  LV +RCLL+K  +   +EKLM++E H+ ++  I     E+ + ++  +   IR   G+   T+ +I  +  I++ ++ ++    +     +Y +  LLS  CVPNT    DE+KDF +T+ ++  ISK + IT       T  GT +RR+ L+  +   C C RC DP E G+F+SA  C KC      ++G +L  NP++ E+ W C          +C  Y +T+ +++ L++R+   +++  C D E +  +F+   R++LHP+HYL +  K  L  L        I+    ++L    E+  +++K+ DI+EPG T  RG  L+ L   +  + +++        E  ++ +  +     + + C E+A  I
Sbjct:   50 MGRYMVAARYFEPGEIIVSETPLVVGPCTGCKVQCLGCYQTLNQKDKYHKCKNCGWPLCSPKCSGISQYYGHSTSECNILKETKSSNFLNYANFDDLKINLHALVPLRCLLLKSLNPSGYEKLMNMEAHNEIRANI----PEVWNGNQKTVVEKIRNDWGLLEYTEEEIHTICGILEVNAFEIGQNGVN-IRGLYPSAFLLSHDCVPNTN-HNDEEKDFRLTIRASLPISKNQPITLS--YAYTLQGTLKRREHLLENKFFECMCKRCSDPTELGTFTSALRCPKC------EKGWVLSTNPLDPEAAWSCNNSQTQESENRCPGYRVTAKSMKLLINRITQEVDSIDCNDIE-RMEEFLEKYRNVLHPSHYLCLGVKLSLSQLYGKINGYLINELTDEQLTRKREICREIMKIFDIIEPGYTRLRGVTLYELHAPIMILTTRQY-------EQEDITKSELRRRLKEVVKCLEQANII 506          

Query:   15 RMASSVAKHLVAIRDIPPGKAIFSETPLAQGPSPDHPNDDDICIVCLSELDHAMVCSKCF--WPVCSSECG----RSDQHKMECATLAACAR------ESEEDLLP-LRHLVVMRCLLMKHRDQYAWEKLMDLEDHHGVQTLIRNVEE-----ELSDMDRLELKYFIRESCGMGIKTDLDIVADIVQSSSIQVDCESLEPFPAMYLTGGLLSQACVPNTVLRFDEDKDFLMTVYSARKISKGEKITFCPLQHLTKSGTRERRKKLMRRLINCFCDRCVDPEECGSFSSAFICQKCAPKGTEDRGLILPINPVEEESPWQCQKCN----YSMTSDTVESLLSRLRDSLEATKCEDNEVKFRDFILSNRSILHPNHYLMIACKDGLFNLKTSEASRAIDISIADKLET--VEMGLDLLKVADILEPGLTSTRGKLLFTLGTTLQEMLSQEVMNRMESPEHAELDERH-----IYSAFHDALFCFEEAKKI 473
            + +  + +++V+ +++ PG  I SE PL  GP          C+ C   L+ +  C+KC   WP+CS +C     R    ++ECA L A         ++ E++ P    +V +RCLL+K  D  +++ LM +E H+ ++   RN+ E     + + +D++ + + +RE      + ++  V  I++ +S ++  + +     +Y +  L+S  CVPNT    DE+  F +TV ++ +I  GE IT     +  +S  + R   L  +   C C RC DP E G+F+SA IC KC        G +L  NP++ E+ W C   N    Y +++ +++ LL ++   ++   C D  +    F+   R++LHP HY+ ++ K  L  L        ID  ++D++ T  +E+  +++KV +++EPG T  RG  L+ +   L  +L+++              ERH     + S     L C EEA  I
Sbjct:   43 KTSKVMGRYMVSRKNLKPGDVILSEAPLVIGPCTGCKVQ---CLGCYKTLESSF-CTKCTCGWPLCSPKCKGLGKRFGHSQVECAVLKATKSSKFLNYDNFEEMRPNFNAIVPLRCLLLKETDARSYQHLMTMETHNEIR---RNIPELWQTNQRTVVDKIRIDWGLREYS----QEEIHSVCGILEVNSFEIGQQGVN-IRGLYPSAFLMSHDCVPNTN-HIDEESTFRLTVRASTRIEPGEMITL-SYAYTLQSTLKRREHLLENKFFECQCRRCSDPTELGTFTSALICPKCKD------GFVLSSNPLDPEADWTCSNYNKCPGYKISAKSMQLLLDKITQEVDNIDCND-VITMETFLKKYRNVLHPTHYINLSVKLSLSQLYGRINGFLID-ELSDEVLTRKLEICEEIIKVFNVIEPGFTRLRGVTLYEMHAPLMVLLTRQF-------------ERHCTKSELRSKLKKVLKCLEEASVI 495          

Query:   15 RMASSVAKHLVAIRDIPPGKAIFSETPLAQGPSPDHPNDDDICIVC------LSELDHAMVCSKCFWPVCSSECGRSDQHKMECATLAACARE-------SEEDLLPLRHLVV--MRCLLMKHRDQYAWEKLMDLEDHHGVQTLIRNVEEELSDMDRLELKYFIRESCGMGIKTDLDI-VADIVQSSSIQVDC-ESLEPFPAMYLTGGLLSQACVPNTVLRFDEDKDFLMTVYSARKISKGEKITFCPLQHLTKSGTRERRKKL-MRRLINCFCDRCVDPEECGSFSSAFICQKCAPKGTED--RGLILPINPVEEESPWQCQKCNYSMTSDTVESLLSRLRDSLEATKCEDNEVK-FRDFILSNRSILHPNHYLMIACKDGLFNLKTSEASRAIDISIADKL--ETVEMGLDLLKVADILEPGLTSTRGKLLFTLGTTLQEMLSQEVMNRMESPEHAELDERHIYSAFHDALFCFEEAKKIQRL 476
            +++ ++ +H++A RDI  G+ I  E P   GP    P    +C+ C      LS+      C+KC WP+C  +C +SD HK EC   A C R+          D +   + V+  MR LLMK  D   ++ +M+LE H     L   +   L  + +  L  FI +  G+    +  + VA I  ++S  V   +  +    +YLT  ++  +C+PNT   F  D ++ + V +   I+KGE IT    Q L   GT ERRK L   +  +C C RC DP E G++     C  C   G E+  R +++  NP+EE +PW+C+KC++S+ S  + S  + L   L  +K +    K F +FI     ILHP ++L++  K  L  +  +     +   ++D L    +++  +LL++AD LEPG +  RG LL  L   +        M    + E  +L +         ++   +EA  I ++
Sbjct:   54 QISDTLGRHMIATRDIKQGEMILKEKPAVLGPKICSP---ALCLTCGKRLEPLSDTCDFYKCTKCQWPMCGPQCEKSDVHKPECN--AMCNRKYRCRIKYESPDKVESAYCVISPMRVLLMKESDPLQYDNIMNLESH-----LDERINTPLYLVLKANLVTFINQVLGLPFDEETILKVASIFDTNSFDVRSPDGTKKLRGIYLTSSMMDHSCLPNTKHVFVGD-EYHLAVIATVPIAKGELITATYTQSLW--GTLERRKHLKTNKWFDCTCARCQDPTEFGTYLGNIYCSLCNFLGNENVSRPMLVSTNPLEENAPWKCEKCDHSILSRQMVSGNNVLNQEL--SKLDKRGPKDFEEFIGKYSQILHPRNHLVVQAKLALVQIYGNYKGYTLS-ELSDNLLKRKIDICYELLEIADQLEPGWSKFRGTLLLDLQAAM-------TMQTKRNYESGKLTKEGTQDQLMQSMGLLQEATNILKV 515          

Query:   22 KHLVAIRDIPPGKAIFSETPLAQGPSPDHPNDDDICIVCLSELDHAMV---CSKCFWPVCSSECGRSDQH----KMECATLAACARES---EEDLLPLR----HLVVMRCLLMKHRDQYAWEKLMDLEDHHGVQTLIRNVEEELS-DMDRLELKYFIRESCGMGIKTDLDIVADIVQSSSIQVDCESLEPFPAMYLTGGLLSQACVPNTVLRFDEDKDFLMTVYSARKISKGEKITFCPLQHLTKSGTRERRKKLM-RRLINCFCDRCVDPEECGSFSSAFICQKCAPKGTEDRGLILPINPVEEESPWQCQ---KC--NYSMTSDTVESLLSRLRDSLEATKCEDNEVKFRDFILSN-RSILHPNHYLMIACKDGLFNLKTSEASRAI-DISIADKLETVEMGLDLLKVADILEPGLTSTRGKLLFTLGTTLQEMLSQEV 439
            +++VA +DI PG+ I SE PL  GP  D       C+ C  +L+  +    CSKC WP+CS +C    +H    ++EC  L  C   S    +DL  LR     +V +RCL++K  D   +  LMD+E H+ ++   RN+ +  + +  R+  +           + ++  +  I++ ++ Q+  + +     +Y T  LLS  CVPNT    DE+  + +T+ ++ KI +G  IT       T   T +RR+ L+  +   C C+RC D  E G++  A IC KC      D GL+L  NP++ +S W C    KC   YS+++ ++  LL+R+ D ++   C  N++K  +  L   R++LHPNHYL +  K  L  +    +   I ++     L   E+  ++L V D++EPGLT  RG  L+ +   +  +L++++
Sbjct:    4 RYIVAKKDIKPGEVIISEEPLVIGPCTDCKVQ---CLGCYKDLEKEIRLFRCSKCGWPMCSKQCPGIKKHHGHTEIECTILQECKSASFFNYDDLEDLRTHFQAIVPLRCLILKTTDPERYAILMDMESHNEIR---RNIPDLWALNQSRVVNRIIKHWKLTEFSEEEIHTICGILEVNTFQIGQQGIN-IRGLYPTSFLLSHNCVPNTN-HTDEEDTYELTIRASTKIQEGHPITLS--YAYTLQCTSKRREHLLENKFFECRCERCSDQTELGTYCGALICPKC------DNGLVLCDNPLDFDSTWSCNNTAKCCAGYSISATSMNLLLNRISDEVDQIDC--NDIKSMELFLEKYRNVLHPNHYLCLGIKIYLSQVYGRISGYIIQELDEKPLLRKKEICKEILSVFDVIEPGLTRIRGVTLYEIHAPVMILLTRQM 426          

Query:   15 RMASSVAKHLVAIRDIPPGKAIFSETPLAQGPSPDHPNDDDICIVCLSELDHAMV---CSKCFWPVCSSECGRSDQH----KMECATLAACARES---EEDLLPLR----HLVVMRCLLMKHRDQYAWEKLMDLEDHHGVQTLIRNVEEELS-DMDRLELKYFIRESCGMGIKTDLDIVADIVQSSSIQVDCESLEPFPAMYLTGGLLSQACVPNTVLRFDEDKDFLMTVYSARKISKGEKITFCPLQHLTKSGTRERRKKLM-RRLINCFCDRCVDPEECGSFSSAFICQKCAPKGTEDRGLILPINPVEEESPWQCQ---KC--NYSMTSDTVESLLSRLRDSLEATKCEDNEVKFRDFILSN-RSILHPNHYLMIACKDGLFNLKTSEASRAI-DISIADKLETVEMGLDLLKVADILEPGLTSTRGKLLFTLGTTLQEMLSQEV 439
            + +  + +++VA +DI PG+ I SE PL  GP  D       C+ C  +L+  +    CSKC WP+CS +C    +H    ++EC  L  C   S    +DL  LR     +V +RCL++K  D   +  LMD+E H+ ++   RN+ +  + +  R+  +           + ++  +  I++ ++ Q+  + +     +Y T  LLS  CVPNT    DE+  + +T+ ++ KI +G  IT       T   T +RR+ L+  +   C C+RC D  E G++  A IC KC      D GL+L  NP++ +S W C    KC   YS+++ ++  LL+R+ D ++   C  N++K  +  L   R++LHPNHYL +  K  L  +    +   I ++     L   E+  ++L V D++EPGLT  RG  L+ +   +  +L++++
Sbjct:   42 KTSKIMGRYIVAKKDIKPGEVIISEEPLVIGPCTDCKVQ---CLGCYKDLEKEIRLFRCSKCGWPMCSKQCPGIKKHHGHTEIECTILQECKSASFFNYDDLEDLRTHFQAIVPLRCLILKTTDPERYAILMDMESHNEIR---RNIPDLWALNQSRVVNRIIKHWKLTEFSEEEIHTICGILEVNTFQIGQQGIN-IRGLYPTSFLLSHNCVPNTN-HTDEEDTYELTIRASTKIQEGHPITLS--YAYTLQCTSKRREHLLENKFFECRCERCSDQTELGTYCGALICPKC------DNGLVLCDNPLDFDSTWSCNNTAKCCAGYSISATSMNLLLNRISDEVDQIDC--NDIKSMELFLEKYRNVLHPNHYLCLGIKIYLSQVYGRISGYIIQELDEKPLLRKKEICKEILSVFDVIEPGLTRIRGVTLYEIHAPVMILLTRQM 471          

Query:   20 VAKHLVAIRDIPPGKAIFSETPLAQGPSPDHPNDDDICIVCLSEL-------DHAMVCSKCFWPVCSSECGRSDQHKMECATLAACARESEEDLLPLRH---------LVVMRCLLMKHRDQYAWEKLMDLEDHHGVQTLIRNVEEELSDMDRLELKYFIRESCGMGIKTDLDI--VADIVQSSSIQV-DCESLEPFPAMYLTGGLLSQACVPNTVLRFDEDKDFLMTVYSARKISKGEKITFCPLQHLTKSGTRERRKKLMR-RLINCFCDRCVDPEECGSFSSAFICQKCAPKGTEDRGLILPINPVEEESPWQCQKCNYSMTSDTVESLLSRLRDSLEATKCEDNEVKFRDFILSNRSILHPNHYLMIACKDGLFNLKTSEASRAIDISIADKLE-TVEMGLDLLKVADILEPGLTSTRGKLLFTLGTTL 431
            + +HL A RDI  G+ I  E PL  GP         +C+ C   L        +   CS C WP+C  EC  S  HK EC  ++    +S+ + +P            ++++RC+ +K +D  A+ KL +LEDH     L   +E  L  + R  L  FI+   GM    ++DI  +A I+ +++ +V          A+Y    ++S  CVPN   RFD+D + L    + RKI+KGE ++    Q L    T +RR  L + +  +C C RC DPEE GSF+ A  C KC        G I+ +NP+   +PW+CQ CN+  ++  V +  + L+  LE+   +   V   +FI  +R+ LH  +  ++  K  L  L  S    A++    + L   +++  +LLK+ADI + G +  RG LL  +   L
Sbjct:   57 LGRHLRATRDIKIGEQILKEAPLVLGPKV---ASAPLCLGCHRNLLAPGKPRGNYHKCSSCSWPLCGKECEDSVHHKAECQLMSGSNFQSKINYVPGEEERKESAYCVIMLLRCMHLKDKDPDAFLKLYNLEDH-----LKERLETPLYQVLRANLITFIKTVLGMKDWPEMDILRIAAILDTNTFEVRQPRERRKIRALYPGAAMISHDCVPNMRHRFDDDMNILF--LAKRKIAKGEILSISYTQPL--RSTIQRRVHLRQAKCFDCSCARCQDPEELGSFAGAQTCLKCKA------GKIISLNPLLNSAPWKCQLCNFKRSAKDVVTSDAELQQELESLD-KTTPVALEEFIYRHRADLHETNTHILQAKYALTQLYGSAPGFAMEELSGESLNRKLQLCEELLKLADIFDGGWSIFRGNLLIDMEEAL 470          

Query:   20 VAKHLVAIRDIPPGKAIFSETPLAQGPSPDHPNDDDICIVCLSELD--HAMVCSKCFWPVCSSEC-GRSDQH---KMECATLAACARESEEDLL---PLRHLVVMRCLLMKHRDQYAWEKLMDLEDHHGVQTLIRNVEE--ELSDMDRLELKYFIRESCGMGIKTDLDIVADIVQSSSIQVDCESLEPFPAMYLTGGLLSQACVPNTVLRFDEDKDFLMTVYSARKISKGEKITFCPLQHLTKSGTRERRKKL-MRRLINCFCDRCVDPEECGSFSSAFICQKCAPKGTEDRGLILPINPVEEESPWQCQKCN-YSMTSDTVESLLSRLRDSLEATKCEDNEVKFRDFILSNRSILHPNHYLMIACKDGLFNLKTSEASRAIDISIADKL--ETVEMGLDLLKVADILEPGLTSTRGKLLFTLGTTLQEMLSQ 437
            + ++LVA RDI     IF E  L  GPS D      +C+ C   L+   +  CSKC WP+C+++C G   +H   + ECA LA CA  +  DL        +V +RCLL+K  +   W  L  LE H+ ++  +  + E  +   +DR+   + + E     I T    V   ++ ++ +V    +    A+Y    L++  C PNT    ++++++ + V +A +I +G+ IT       T  GT  RR+ L   +  +C C RC DP E G+  S+  C KC       +G +L   P+++++ W C  C+ YS+   T+E L+ R+++ L++    D+ V   +F+     +LHP HY+MIA K  L  L        I   ++D L     ++  +LLKV D++EPG +  RG  L+ +   +  + ++
Sbjct:   52 IGRYLVASRDIEQASVIFHEDALVVGPSQD---TRPLCLGCYKSLNLTTSSRCSKCTWPLCANDCPGLHTEHGHSEAECAALAKCAPPTVNDLTTHKAYNAIVPLRCLLLKSHNPAKWNILQTLEAHNSIRKKLNYIWECNQKYIVDRIRNTWKMEEYAEEEIHT----VCGYLEVNAFEVGQGGIS-IRALYPNVFLVAHDCTPNT--SHNDNENYQLVVRAASRIKQGQLITLSYAN--TLHGTLRRREHLRTAKFFDCICARCSDPTELGTNLSSLKCPKCL------KGAVLSTKPLDDKADWLCTNCSQYSVPYHTIEKLIERIQNGLDSIGM-DSVVDLENFLKKYEKVLHPQHYIMIAAKYSLSQLYGKAPGYVIH-QLSDDLLMRKRDICSELLKVFDVIEPGYSRLRGVTLYEIHAPIMILFTR 464