BLAST of EMLSAG00000000343 vs. GO
Match: - (symbol:SMPD2 "Uncharacterized protein" species:9823 "Sus scrofa" [GO:0004767 "sphingomyelin phosphodiesterase activity" evidence=IEA] Pfam:PF03372 GO:GO:0008152 Gene3D:3.60.10.10 InterPro:IPR005135 SUPFAM:SSF56219 GO:GO:0004767 GeneTree:ENSGT00390000009166 KO:K12351 OrthoDB:EOG7SXW3M CTD:6610 OMA:QARWWAT TreeFam:TF313899 EMBL:CU075452 RefSeq:XP_001925325.1 UniGene:Ssc.47535 Ensembl:ENSSSCT00000004871 GeneID:100152155 KEGG:ssc:100152155 Uniprot:F1RSY4)

HSP 1 Score: 191.43 bits (485), Expect = 3.408e-54
Identity = 102/261 (39.08%), Postives = 155/261 (59.39%), Query Frame = 0

Query:   15 ERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIR 275
            +RV+ L  +L+  E +D+VLL+EVW+++D++ L++ L+ +   +  +HYF +GIIG+G C+FSK  I+  T H F LNGYP  + HGDWF  K +G+ VL++ G  ++ YV+H HAEY+ + DIYL HRV  A E AQ+I  TS  AD+ +  GD N  P  +  +LLK  T L D++ E      +EEG T     N +  +   +  P G RIDY++Y+A +   +  K  +   +   P      SDHEA+ +T  +R
Sbjct:   28 DRVKRLGDFLNM-ESFDLVLLEEVWSEQDFQYLRQKLLPT---YPAAHYFRSGIIGSGLCVFSKHPIQEFTQHVFTLNGYPYMVHHGDWFCGKAVGLLVLHLSGLVLNAYVTHLHAEYSRQKDIYLAHRVAQAWELAQFIHHTSKKADVVLLCGDLNLHPKDLGCRLLKEWTGLHDAFLETRDFKGSEEGCTM-VPENCYVNQRELEQFPVGIRIDYVLYKAVSGLYISCKT-LKTTTGSDPHSGTPLSDHEALMATLCVR 282          

BLAST of EMLSAG00000000343 vs. GO
Match: - (symbol:CG12034 species:7227 "Drosophila melanogaster" [GO:0004767 "sphingomyelin phosphodiesterase activity" evidence=ISS;NAS] [GO:0006684 "sphingomyelin metabolic process" evidence=ISS] UniPathway:UPA00222 Pfam:PF03372 GO:GO:0016021 EMBL:AE014296 GO:GO:0046872 GO:GO:0006665 Gene3D:3.60.10.10 InterPro:IPR005135 SUPFAM:SSF56219 GO:GO:0004767 eggNOG:NOG269293 GeneTree:ENSGT00390000009166 KO:K12351 EMBL:AY051714 RefSeq:NP_647790.1 UniGene:Dm.4499 ProteinModelPortal:Q9VZS6 BioGrid:63892 DIP:DIP-18690N IntAct:Q9VZS6 MINT:MINT-808855 PaxDb:Q9VZS6 PRIDE:Q9VZS6 EnsemblMetazoa:FBtr0073043 GeneID:38396 KEGG:dme:Dmel_CG12034 UCSC:CG12034-RA FlyBase:FBgn0035421 InParanoid:Q9VZS6 OMA:IRIDHIF OrthoDB:EOG7SXW3M PhylomeDB:Q9VZS6 ChiTaRS:CG12034 GenomeRNAi:38396 NextBio:808410 PRO:PR:Q9VZS6 Bgee:Q9VZS6 Uniprot:Q9VZS6)

HSP 1 Score: 189.889 bits (481), Expect = 1.830e-53
Identity = 102/292 (34.93%), Postives = 163/292 (55.82%), Query Frame = 0

Query:   14 RERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSNKCPLVDYKRSLSVKCQSERFEVVT 305
            R R+ A+   L++ + YDIV LQEVW  ED + L+K    +      SHYF +G++G G  + SK  I  T FH++ +NGY   I H DWF  KG+G+  + + G  +H+Y +H HAEY+  ND Y  HRV+ A ++AQ+I+ T  ++ L I AGD N +P  +  K+L Y + + DS +       ++   T E  +NS+T +  ++  P G RID+I  + G   +    +  LP  +RVPG+ +S+SDHEAV +  ++ +    ++ P+     ++ V C  E  E  +
Sbjct:   24 RPRIDAICKELASGK-YDIVSLQEVWAQEDSELLQKG---TEAVLPHSHYFHSGVMGAGLLVLSKYPILGTLFHAWSVNGYFHRIQHADWFGGKGVGLCRILVGGQMVHLYNAHLHAEYDNANDEYKTHRVIQAFDTAQFIEATRGNSALQILAGDLNAQPQDISYKVLLYTSKMLDSCD-------SDSFRTNECEHNSYTSKQARERNPLGIRIDHIFVRGGDHVNAEIAEYKLPFPERVPGEKFSFSDHEAVMAKLKLFKLEPRSEEPVA----TIEVNCLVEDGETCS 300          

BLAST of EMLSAG00000000343 vs. GO
Match: - (symbol:SMPD2 "Uncharacterized protein" species:9615 "Canis lupus familiaris" [GO:0004767 "sphingomyelin phosphodiesterase activity" evidence=IEA] Pfam:PF03372 GO:GO:0008152 Gene3D:3.60.10.10 InterPro:IPR005135 SUPFAM:SSF56219 GO:GO:0004767 GeneTree:ENSGT00390000009166 OrthoDB:EOG7SXW3M OMA:QARWWAT TreeFam:TF313899 EMBL:AAEX03008595 Ensembl:ENSCAFT00000006143 Uniprot:E2RQN3)

HSP 1 Score: 189.119 bits (479), Expect = 2.821e-53
Identity = 99/261 (37.93%), Postives = 153/261 (58.62%), Query Frame = 0

Query:   15 ERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIR 275
            +R++ L   L+  E +D+ LL+EVW+++D++ L++ L+ +   +  +HYF +G+IG+G C+FSK  I+  T H + LNGYP  I HGDWF  K +G+ VL++ G  ++ YV+H HAEYN + D+YL HRV  A E AQ+I  TS  AD+ +  GD N  P  +  +LLK  T L D++ E      +EEG T     N +  +   +  P G RIDY++Y+A +   +  K  +   +   P      SDHEA+ +T  +R
Sbjct:   28 DRMKRLGDLLNM-ESFDLALLEEVWSEQDFQRLRQKLLPA---YPAAHYFRSGVIGSGLCVFSKHPIQEFTQHVYTLNGYPYMIHHGDWFCGKAVGLLVLHLSGLVLNAYVTHLHAEYNRQKDVYLTHRVAQAWELAQFIHHTSKKADVVLLCGDLNLHPKDLGCRLLKECTGLHDAYHETRDFKGSEEGCTM-VPENCYVSQRELEPFPFGIRIDYVLYKAVSGFYISCKT-LRTTTGHDPHSGTPLSDHEALMATLCVR 282          

BLAST of EMLSAG00000000343 vs. GO
Match: - (symbol:smpd2a "sphingomyelin phosphodiesterase 2a, neutral" species:7955 "Danio rerio" [GO:0005794 "Golgi apparatus" evidence=IDA] [GO:0046513 "ceramide biosynthetic process" evidence=IMP] [GO:0004767 "sphingomyelin phosphodiesterase activity" evidence=IMP;IDA] [GO:0006684 "sphingomyelin metabolic process" evidence=IMP] [GO:0071466 "cellular response to xenobiotic stimulus" evidence=IMP] Pfam:PF03372 ZFIN:ZDB-GENE-051014-1 GO:GO:0005794 GO:GO:0071466 GO:GO:0046513 Gene3D:3.60.10.10 InterPro:IPR005135 SUPFAM:SSF56219 GO:GO:0004767 GO:GO:0006684 GeneTree:ENSGT00390000009166 KO:K12351 OMA:IRIDHIF OrthoDB:EOG7SXW3M TreeFam:TF313899 EMBL:CU570774 RefSeq:XP_005170892.1 UniGene:Dr.47411 Ensembl:ENSDART00000059307 GeneID:567548 KEGG:dre:567548 CTD:567548 Bgee:F1QUD7 Uniprot:F1QUD7)

HSP 1 Score: 188.348 bits (477), Expect = 4.133e-53
Identity = 109/309 (35.28%), Postives = 165/309 (53.40%), Query Frame = 0

Query:    9 LPRSCRERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSNKCPLVDYKRSLSVKCQSERFEVVTEALEIIHRSEGL 317
            L + C +R + +   L  +E +DI LLQEVW++ D+  LK+ L  S     ++HYF +G+IG+G  +FSK RI+    + + LNGYP  +SHGDWF  K  G+ ++ + G + HVYV+H HAEY+   D YL HR+V + E  Q+++ TS  ADL I  GD N  P  +  +LL+  T L+D + E    +  E+G T     N FT +       +G RIDYI+ + G+    V  + +      V  K + YSDHEA+ +   +    D    P             S++ +VV+EA  ++   EGL
Sbjct:   22 LSKLCAQRYEMIGELL-GREQHDIALLQEVWSERDFLFLKRKLSCS---HPYTHYFKSGVIGSGLAVFSKHRIQDALLYQYSLNGYPYMLSHGDWFGGKAAGLVIVEVFGLKAHVYVTHLHAEYSRAQDGYLPHRIVQSWELQQFVRHTSHGADLVILGGDLNMHPQDLGNRLLRSHTGLRDCYTETDKFDGCEDGHTL-IANNHFTKKQDLIPFEKGIRIDYILIK-GSQRVSVKCESLSTTKGSVSDKPFPYSDHEALMADLNLLSSQDCTDAPPA-----------SDQMDVVSEARAVV--KEGL 311          

BLAST of EMLSAG00000000343 vs. GO
Match: - (symbol:SMPD2 "Uncharacterized protein" species:9913 "Bos taurus" [GO:0004767 "sphingomyelin phosphodiesterase activity" evidence=IEA] Pfam:PF03372 GO:GO:0008152 Gene3D:3.60.10.10 InterPro:IPR005135 SUPFAM:SSF56219 GO:GO:0004767 GeneTree:ENSGT00390000009166 EMBL:DAAA02025917 KO:K12351 OrthoDB:EOG7SXW3M CTD:6610 OMA:QARWWAT TreeFam:TF313899 RefSeq:NP_001068851.2 UniGene:Bt.5770 Ensembl:ENSBTAT00000010706 GeneID:509018 KEGG:bta:509018 NextBio:20868780 Uniprot:F1N588)

HSP 1 Score: 186.422 bits (472), Expect = 2.475e-52
Identity = 101/261 (38.70%), Postives = 150/261 (57.47%), Query Frame = 0

Query:   15 ERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIR 275
            +RV+ L  +L+  E +D+ LL+EVW+++D++ L++ L+ +   +  +HYF +GIIG+G C+FSK  I+  T H F LNGYP  I H DWF  K +G+ VL++ G  ++ YV+H HAEYN + D YL HRV  A E AQ+I  TS  AD+ +  GD N  P  +  +LLK  T L D++ E      +EEG T     N +         P G RIDY++Y+A +   +  K      +   P     +SDHEA+ +T  +R
Sbjct:   28 DRVKRLGDFLNM-ESFDLALLEEVWSEQDFQYLRQKLLPT---YPAAHYFRSGIIGSGLCVFSKHPIQEFTQHVFTLNGYPYMIHHCDWFCGKAVGLLVLHLSGLVLNAYVTHLHAEYNRQKDTYLAHRVAQAWELAQFIHHTSKKADVVLLCGDLNLHPKDLGCRLLKEWTGLHDAYLETRDFKGSEEGCTM-VPKNCYVKHQELGPFPLGIRIDYVLYKAVSGLYIFCKT-FKTTTGHDPYSGPPFSDHEALMATLCVR 282          

BLAST of EMLSAG00000000343 vs. GO
Match: - (symbol:SMPD2 "Sphingomyelin phosphodiesterase 2" species:9606 "Homo sapiens" [GO:0004767 "sphingomyelin phosphodiesterase activity" evidence=IEA] [GO:0005886 "plasma membrane" evidence=TAS] [GO:0005887 "integral component of plasma membrane" evidence=TAS] [GO:0005901 "caveola" evidence=IEA] [GO:0006665 "sphingolipid metabolic process" evidence=TAS] [GO:0006684 "sphingomyelin metabolic process" evidence=TAS] [GO:0006687 "glycosphingolipid metabolic process" evidence=TAS] [GO:0009612 "response to mechanical stimulus" evidence=IEA] [GO:0044281 "small molecule metabolic process" evidence=TAS] [GO:0046513 "ceramide biosynthetic process" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] [GO:0048011 "neurotrophin TRK receptor signaling pathway" evidence=TAS] [GO:0097190 "apoptotic signaling pathway" evidence=TAS] Reactome:REACT_111217 UniPathway:UPA00222 Pfam:PF03372 Reactome:REACT_111102 GO:GO:0048011 GO:GO:0005887 GO:GO:0009612 GO:GO:0046872 GO:GO:0005901 GO:GO:0097190 GO:GO:0046513 Gene3D:3.60.10.10 InterPro:IPR005135 SUPFAM:SSF56219 GO:GO:0006687 GO:GO:0004767 GO:GO:0006684 eggNOG:NOG269293 BRENDA:3.1.4.12 EMBL:AL109947 HOGENOM:HOG000044683 KO:K12351 OrthoDB:EOG7SXW3M EMBL:AJ222801 EMBL:BC000038 RefSeq:NP_003071.2 UniGene:Hs.55235 ProteinModelPortal:O60906 BioGrid:112494 STRING:9606.ENSP00000258052 BindingDB:O60906 ChEMBL:CHEMBL4712 PhosphoSite:O60906 PaxDb:O60906 PRIDE:O60906 DNASU:6610 Ensembl:ENST00000258052 GeneID:6610 KEGG:hsa:6610 UCSC:uc003pti.3 CTD:6610 GeneCards:GC06P109761 H-InvDB:HIX0006125 HGNC:HGNC:11121 HPA:HPA018110 HPA:HPA018125 MIM:603498 neXtProt:NX_O60906 PharmGKB:PA35970 HOVERGEN:HBG019089 InParanoid:O60906 OMA:QARWWAT PhylomeDB:O60906 TreeFam:TF313899 GeneWiki:SMPD2 GenomeRNAi:6610 NextBio:25735 PRO:PR:O60906 Bgee:O60906 CleanEx:HS_SMPD2 Genevestigator:O60906 Uniprot:O60906)

HSP 1 Score: 186.037 bits (471), Expect = 4.278e-52
Identity = 100/261 (38.31%), Postives = 155/261 (59.39%), Query Frame = 0

Query:   15 ERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIR 275
            +R++ L  +L+ +E +D+ LL+EVW+++D++ L++ L  +   +  +H+F +GIIG+G C+FSK  I+  T H + LNGYP  I HGDWF+ K +G+ VL++ G  ++ YV+H HAEYN + DIYL HRV  A E AQ+I  TS  AD+ +  GD N  P+ +   LLK  T L D++ E      +EEG T     N +  +   +  P G RIDY++Y+A +   +  K      +   P +    SDHEA+ +T  +R
Sbjct:   28 DRMRRLGDFLN-QESFDLALLEEVWSEQDFQYLRQKLSPT---YPAAHHFRSGIIGSGLCVFSKHPIQELTQHIYTLNGYPYMIHHGDWFSGKAVGLLVLHLSGMVLNAYVTHLHAEYNRQKDIYLAHRVAQAWELAQFIHHTSKKADVVLLCGDLNMHPEDLGCCLLKEWTGLHDAYLETRDFKGSEEGNTM-VPKNCYVSQQELKPFPFGVRIDYVLYKAVSGFYISCKS-FETTTGFDPHRGTPLSDHEALMATLFVR 282          

BLAST of EMLSAG00000000343 vs. GO
Match: - (symbol:Smpd2 "Sphingomyelin phosphodiesterase 2" species:10116 "Rattus norvegicus" [GO:0004767 "sphingomyelin phosphodiesterase activity" evidence=TAS] [GO:0005886 "plasma membrane" evidence=TAS] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] UniPathway:UPA00222 Pfam:PF03372 RGD:619753 GO:GO:0016021 GO:GO:0009612 GO:GO:0035556 GO:GO:0046872 GO:GO:0005901 GO:GO:0046513 Gene3D:3.60.10.10 InterPro:IPR005135 SUPFAM:SSF56219 GO:GO:0004767 eggNOG:NOG269293 BRENDA:3.1.4.12 GeneTree:ENSGT00390000009166 HOGENOM:HOG000044683 KO:K12351 OrthoDB:EOG7SXW3M CTD:6610 HOVERGEN:HBG019089 OMA:QARWWAT TreeFam:TF313899 EMBL:AB047002 EMBL:BC091139 RefSeq:NP_112650.1 UniGene:Rn.18572 ProteinModelPortal:Q9ET64 BindingDB:Q9ET64 ChEMBL:CHEMBL3528 PRIDE:Q9ET64 Ensembl:ENSRNOT00000000336 GeneID:83537 KEGG:rno:83537 InParanoid:Q9ET64 NextBio:616049 PRO:PR:Q9ET64 Genevestigator:Q9ET64 Uniprot:Q9ET64)

HSP 1 Score: 179.874 bits (455), Expect = 7.943e-50
Identity = 95/261 (36.40%), Postives = 151/261 (57.85%), Query Frame = 0

Query:   15 ERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIR 275
            +R++ L  +L+  E +D+ LL+EVW+++D++ LK+ L L+   +  +HYF +GIIG+G C+FS+  I+    H + LNGYP    HGDWF  K +G+ VL++ G  ++ YV+H HAEY+ + DIY  HRV  A E AQ+I  TS  A++ +  GD N  P  +   LLK  T L+D++ E      +E+G T     N +  +      P G RIDY++Y+A +   +  K  +   +   P     +SDHEA+ +T  ++
Sbjct:   28 DRMKRLGDFLNL-ESFDLALLEEVWSEQDFQYLKQKLSLT---YPDAHYFRSGIIGSGLCVFSRHPIQEIVQHVYTLNGYPYKFYHGDWFCGKAVGLLVLHLSGLVLNAYVTHLHAEYSRQKDIYFAHRVAQAWELAQFIHHTSKKANVVLLCGDLNMHPKDLGCCLLKEWTGLRDAFVETEDFKGSEDGCT-MVPKNCYVSQQDLGPFPFGVRIDYVLYKAVSGFHICCKT-LKTTTGCDPHNGTPFSDHEALMATLCVK 282          

BLAST of EMLSAG00000000343 vs. GO
Match: - (symbol:Smpd2 "sphingomyelin phosphodiesterase 2, neutral membrane" species:10116 "Rattus norvegicus" [GO:0004767 "sphingomyelin phosphodiesterase activity" evidence=ISO;IDA;TAS] [GO:0005886 "plasma membrane" evidence=TAS] [GO:0005901 "caveola" evidence=IDA] [GO:0009612 "response to mechanical stimulus" evidence=IMP] [GO:0016020 "membrane" evidence=IDA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0035556 "intracellular signal transduction" evidence=IMP] [GO:0046513 "ceramide biosynthetic process" evidence=IDA] [GO:0046872 "metal ion binding" evidence=IEA] UniPathway:UPA00222 Pfam:PF03372 RGD:619753 GO:GO:0016021 GO:GO:0009612 GO:GO:0035556 GO:GO:0046872 GO:GO:0005901 GO:GO:0046513 Gene3D:3.60.10.10 InterPro:IPR005135 SUPFAM:SSF56219 GO:GO:0004767 eggNOG:NOG269293 BRENDA:3.1.4.12 GeneTree:ENSGT00390000009166 HOGENOM:HOG000044683 KO:K12351 OrthoDB:EOG7SXW3M CTD:6610 HOVERGEN:HBG019089 OMA:QARWWAT TreeFam:TF313899 EMBL:AB047002 EMBL:BC091139 RefSeq:NP_112650.1 UniGene:Rn.18572 ProteinModelPortal:Q9ET64 BindingDB:Q9ET64 ChEMBL:CHEMBL3528 PRIDE:Q9ET64 Ensembl:ENSRNOT00000000336 GeneID:83537 KEGG:rno:83537 InParanoid:Q9ET64 NextBio:616049 PRO:PR:Q9ET64 Genevestigator:Q9ET64 Uniprot:Q9ET64)

HSP 1 Score: 179.874 bits (455), Expect = 7.943e-50
Identity = 95/261 (36.40%), Postives = 151/261 (57.85%), Query Frame = 0

Query:   15 ERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIR 275
            +R++ L  +L+  E +D+ LL+EVW+++D++ LK+ L L+   +  +HYF +GIIG+G C+FS+  I+    H + LNGYP    HGDWF  K +G+ VL++ G  ++ YV+H HAEY+ + DIY  HRV  A E AQ+I  TS  A++ +  GD N  P  +   LLK  T L+D++ E      +E+G T     N +  +      P G RIDY++Y+A +   +  K  +   +   P     +SDHEA+ +T  ++
Sbjct:   28 DRMKRLGDFLNL-ESFDLALLEEVWSEQDFQYLKQKLSLT---YPDAHYFRSGIIGSGLCVFSRHPIQEIVQHVYTLNGYPYKFYHGDWFCGKAVGLLVLHLSGLVLNAYVTHLHAEYSRQKDIYFAHRVAQAWELAQFIHHTSKKANVVLLCGDLNMHPKDLGCCLLKEWTGLRDAFVETEDFKGSEDGCT-MVPKNCYVSQQDLGPFPFGVRIDYVLYKAVSGFHICCKT-LKTTTGCDPHNGTPFSDHEALMATLCVK 282          

BLAST of EMLSAG00000000343 vs. GO
Match: - (symbol:Smpd2 "sphingomyelin phosphodiesterase 2, neutral" species:10090 "Mus musculus" [GO:0004767 "sphingomyelin phosphodiesterase activity" evidence=ISO;IMP] [GO:0005622 "intracellular" evidence=ISO] [GO:0005901 "caveola" evidence=ISO] [GO:0006629 "lipid metabolic process" evidence=IEA] [GO:0006665 "sphingolipid metabolic process" evidence=IEA] [GO:0009612 "response to mechanical stimulus" evidence=ISO] [GO:0016020 "membrane" evidence=ISO] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0016787 "hydrolase activity" evidence=IEA] [GO:0035556 "intracellular signal transduction" evidence=ISO] [GO:0043065 "positive regulation of apoptotic process" evidence=ISO] [GO:0046513 "ceramide biosynthetic process" evidence=ISO] [GO:0046872 "metal ion binding" evidence=IEA] UniPathway:UPA00222 Pfam:PF03372 MGI:MGI:1278330 GO:GO:0016021 GO:GO:0009612 GO:GO:0046872 GO:GO:0005901 GO:GO:0046513 Gene3D:3.60.10.10 InterPro:IPR005135 SUPFAM:SSF56219 GO:GO:0004767 eggNOG:NOG269293 GeneTree:ENSGT00390000009166 HOGENOM:HOG000044683 KO:K12351 OrthoDB:EOG7SXW3M CTD:6610 HOVERGEN:HBG019089 OMA:QARWWAT TreeFam:TF313899 EMBL:AJ222800 EMBL:BC010978 RefSeq:NP_033239.1 UniGene:Mm.953 ProteinModelPortal:O70572 MINT:MINT-1657649 STRING:10090.ENSMUSP00000019965 PhosphoSite:O70572 PaxDb:O70572 PRIDE:O70572 Ensembl:ENSMUST00000019965 GeneID:20598 KEGG:mmu:20598 UCSC:uc007exs.1 InParanoid:O70572 ChiTaRS:SMPD2 NextBio:298919 PRO:PR:O70572 ArrayExpress:O70572 Bgee:O70572 CleanEx:MM_SMPD2 Genevestigator:O70572 Uniprot:O70572)

HSP 1 Score: 179.104 bits (453), Expect = 1.105e-49
Identity = 94/261 (36.02%), Postives = 153/261 (58.62%), Query Frame = 0

Query:   15 ERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIR 275
            +R++ L  +L+  E++D+ LL+EVW+++D++ L++ L L+   +  +HYF +G+IG+G C+FSK  I+    H + LNGYP    HGDWF  K +G+ VL + G  ++ YV+H HAEY+ + DIY  HRV  A E AQ+I  TS +AD+ +  GD N  P  +   LLK  T L D++ E      +++G T     N +  +      P G RIDY++Y+A ++  V  +  +   +   P  +  +SDHEA+ +T  ++
Sbjct:   28 DRMKRLGDFLNL-ENFDLALLEEVWSEQDFQYLRQRLSLT---YPDAHYFRSGMIGSGLCVFSKHPIQEIFQHVYSLNGYPYMFHHGDWFCGKSVGLLVLRLSGLVLNAYVTHLHAEYSRQKDIYFAHRVAQAWELAQFIHHTSKNADVVLLCGDLNMHPKDLGCCLLKEWTGLHDAFVETEDFKGSDDGCT-MVPKNCYVSQQDLGPFPSGIRIDYVLYKAVSEFHVCCET-LKTTTGCDPHSDKPFSDHEALMATLYVK 282          

BLAST of EMLSAG00000000343 vs. GO
Match: - (symbol:T27F6.6 "Putative neutral sphingomyelinase" species:6239 "Caenorhabditis elegans" [GO:0004767 "sphingomyelin phosphodiesterase activity" evidence=IEA] [GO:0006629 "lipid metabolic process" evidence=IEA] [GO:0006665 "sphingolipid metabolic process" evidence=IEA] [GO:0016020 "membrane" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0016787 "hydrolase activity" evidence=IEA] [GO:0046872 "metal ion binding" evidence=IEA] UniPathway:UPA00222 Pfam:PF03372 GO:GO:0016021 GO:GO:0046872 GO:GO:0006665 Gene3D:3.60.10.10 InterPro:IPR005135 SUPFAM:SSF56219 GO:GO:0004767 eggNOG:NOG269293 GeneTree:ENSGT00390000009166 EMBL:Z82060 PIR:T25386 RefSeq:NP_493169.2 UniGene:Cel.8884 ProteinModelPortal:O45870 STRING:6239.T27F6.6 PaxDb:O45870 EnsemblMetazoa:T27F6.6.1 EnsemblMetazoa:T27F6.6.2 GeneID:173118 KEGG:cel:CELE_T27F6.6 UCSC:T27F6.6 CTD:173118 WormBase:T27F6.6 HOGENOM:HOG000044683 InParanoid:O45870 KO:K12351 OMA:KGVGLCK NextBio:878333 PRO:PR:O45870 Uniprot:O45870)

HSP 1 Score: 176.022 bits (445), Expect = 2.774e-48
Identity = 119/409 (29.10%), Postives = 202/409 (49.39%), Query Frame = 0

Query:    6 PSVLPRSCRERVQALS---HYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDG-FEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWE---EVHGSNANEE---------GATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSNKCPLVDYKRSLSVKCQSERFEVVTEALEIIHRSEGLVSYNGTKYLMIASGLLILLILSLLPSLIESSIQQYMDLAMFFPRLIVTIIMTFYLIMGFAFNRRELNELRSTKSSLKVIFD 398
            P   P    +RV  L+    Y+   E YDIV LQE+W+  D+  L + +      + + HYF +G  G+G C+FS+  I  T  + + LNG+   I  GDWF  K +G+  + IDG   ++ Y +H HAEY+ END+YL HR   A E AQ+++ T+  AD+ I  GD N EP  +  +L+     L D+W    EV   ++  E         G TC+   N +T  ++K    + KRIDY+++++G   +V  ++C + L++ +PG++ +YSDH  + + F I  +    K          SV        ++ EA+ ++   E     +   + ++A   LIL++ SL   +        M  A+   R  +T++  F++  G      E   L++ K +++ I +
Sbjct:   50 PQPWPIGSTDRVHRLNKIGQYM-IDELYDIVGLQELWSYYDFVRLSEQV---SSVYPYFHYFHSGFTGSGVCVFSRHPIVSTLTNRYSLNGFAHHIHRGDWFGGKVVGLTEIEIDGDLRVNFYTTHLHAEYDRENDLYLPHRTAQAFELAQFVRHTARGADVVIVTGDLNMEPCDLGFRLILSHAKLFDAWRMSHEVENEDSEGELLKFRGIAKGGTCDRPDNCYTKRALKNV-DDSKRIDYMLFKSGR-CNVKLEECEITLNQ-IPGEDLNYSDHVGLRARFTIDDRFRHEK----------SVNTWEPNRPLLIEAIGLVAGGERRARTDRIFFFILAVICLILILGSLFFEVFP------MGFAVL--RFALTVVGVFFVWQGLIGLTLERKALKAAKQAIQQILN 433          

BLAST of EMLSAG00000000343 vs. C. finmarchicus
Match: gi|592859605|gb|GAXK01097957.1| (TSA: Calanus finmarchicus comp38672_c0_seq1 transcribed RNA sequence)

HSP 1 Score: 317.39 bits (812), Expect = 5.649e-101
Identity = 176/391 (45.01%), Postives = 243/391 (62.15%), Query Frame = 0

Query:   15 ERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHA--EYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSNKCPLV---DYKRSLSVKCQSERFEVVTEALEIIHRSEGLVSYNGTKYXXXXXXXXXXXXXXXXXXXXXXXXQQY--MDLAMFFPRLIVTIIMTFYLIMGFAFNRRELNELRSTKSSLKVIFD 398
            ER++ +  YL A +D+DIV LQE+W   ++ T+K  L+ S  P+  SH+FDNGIIGTGT IF+K +I+  TFH FGLNGYP  + HGDWF  KGLG+  +   GF IH++VSHYHA  +YNP  D+YLGHRVVH++ESAQWI+L+S+SADLTIYAGDFNTEP  VP ++++Y+T L DSW E +G +    G T ET  N++T +S  +  PEGKRIDYIMY +G +    T  C LPL  R+PGK+ SYSDHE V S   I+R    N   ++   D+ R  S K    + E V +  EI+  S   V +    Y      LL   +  LL        ++Y  +D+A+F  RL + +  T+  +M   F R+E + L  T + L+++ +
Sbjct:  124 ERMEDIGKYL-ADQDFDIVFLQEIWKRNNFNTVK-GLVSSVLPY--SHFFDNGIIGTGTAIFTKVKIKDVTFHEFGLNGYPHKLLHGDWFGGKGLGVCQIDFKGFNIHLFVSHYHATYDYNPLTDVYLGHRVVHSVESAQWIKLSSSSADLTIYAGDFNTEPKDVPYQIVRYVTPLCDSWVEANGPDG---GQTSETPSNTYTAKSSLKESPEGKRIDYIMYNSGPNITASTVYCELPLPDRIPGKSISYSDHEGVNSKLLIKR----NTGEMITSRDFVRMQSRKDLQSKLECVEQGKEILKNSLKSVRFARIMY------LLGAALCLLLLVAAFLPTKEYIGLDIALFVLRLGLIVTGTYLFLMSLLFFRKERHALNGTLACLELLLE 1245          

BLAST of EMLSAG00000000343 vs. C. finmarchicus
Match: gi|592791130|gb|GAXK01163438.1| (TSA: Calanus finmarchicus comp219954_c2_seq1 transcribed RNA sequence)

HSP 1 Score: 306.99 bits (785), Expect = 2.979e-98
Identity = 170/388 (43.81%), Postives = 234/388 (60.31%), Query Frame = 0

Query:   16 RVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVP-------GKNYSYSDHEAVESTFRIRRKMDSNKCPLVDYKRSLSVKCQSERFEVVTEALEIIHRSEGLVSYNGTKYXXXXXXXXXXXXXXXXXXXXXXXXQQYMDLAMFFPRLIVTIIMTFYLIMGFAFNRRELNELRSTKSSLKVI 396
            R +A++ +L A  DYDIV LQEVW   DY+T+   + ++     F+H+FDNGIIGTGTCI SK+ I+  TFH F LNGYP  + HGDWFA KGLG+  +   G  IHV+VSH+HAEY+  +DIYLGHRV+ ALE+AQWI+LTS+ ADLTIYAGDFNTEP  VP  LL+ + SL DSW + HG +  E   TC T YN++   +     P GKRIDYIMY+AG D  V   +C LPL++R+P       GK  SYSDHEAV +   +   +      L    R    +  + R E V   + II ++  L+     + L     ++  +I     S +       +D  MF  R+I+T+   + ++M   FNRRE + L +TK++L+++
Sbjct:   89 RFRAIAQHL-ADSDYDIVCLQEVWCPSDYRTI---IDVARDALPFNHFFDNGIIGTGTCILSKAPIQDATFHEFSLNGYPHKVLHGDWFAGKGLGVCGIDYKGLNIHVFVSHFHAEYSRSDDIYLGHRVMQALEAAQWIKLTSSGADLTIYAGDFNTEPVDVPYSLLRSVGSLSDSWVDAHGVDGGE---TCGTPYNTYCTINEVAEYPMGKRIDYIMYRAGPDKTVQITECRLPLARRIPASLSACLGKEVSYSDHEAVAAIITVADNVGPEGDNLGHTARQARGR-NAGRQEAVAAGIIIIEKA--LLGTKTDQKLYSVLAIITFIIFMASFSQLLLMDSLLLDCIMFLLRMILTLTGFYAVLMATVFNRRERHALSATKATLQLL 1222          

BLAST of EMLSAG00000000343 vs. C. finmarchicus
Match: gi|592791129|gb|GAXK01163439.1| (TSA: Calanus finmarchicus comp219954_c2_seq2 transcribed RNA sequence)

HSP 1 Score: 290.812 bits (743), Expect = 4.446e-94
Identity = 144/266 (54.14%), Postives = 182/266 (68.42%), Query Frame = 0

Query:   16 RVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVP-------GKNYSYSDHEAVESTFRI 274
            R +A++ +L A  DYDIV LQEVW   DY+T+   + ++     F+H+FDNGIIGTGTCI SK+ I+  TFH F LNGYP  + HGDWFA KGLG+  +   G  IHV+VSH+HAEY+  +DIYLGHRV+ ALE+AQWI+LTS+ ADLTIYAGDFNTEP  VP  LL+ + SL DSW + HG +  E   TC T YN++   +     P GKRIDYIMY+AG D  V   +C LPL++R+P       GK  SYSDHEAV +T  +
Sbjct:   89 RFRAIAQHL-ADSDYDIVCLQEVWCPSDYRTI---IDVARDALPFNHFFDNGIIGTGTCILSKAPIQDATFHEFSLNGYPHKVLHGDWFAGKGLGVCGIDYKGLNIHVFVSHFHAEYSRSDDIYLGHRVMQALEAAQWIKLTSSGADLTIYAGDFNTEPVDVPYSLLRSVGSLSDSWVDAHGVDGGE---TCGTPYNTYCTINEVAEYPMGKRIDYIMYRAGPDKTVQITECRLPLARRIPASLSACLGKEVSYSDHEAVAATITV 865          

BLAST of EMLSAG00000000343 vs. C. finmarchicus
Match: gi|592837771|gb|GAXK01119773.1| (TSA: Calanus finmarchicus comp653278_c0_seq1 transcribed RNA sequence)

HSP 1 Score: 233.417 bits (594), Expect = 4.155e-69
Identity = 131/398 (32.91%), Postives = 208/398 (52.26%), Query Frame = 0

Query:   14 RERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEE-GATCETYYN---------SFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSNKCPLVDYKRSLSVKCQSERFEVVTEALEIIHRSEGLVSYNGTKYXXXXXXXXXXXXXXXXXXXXXXXXQQYMDLAMFFPRLIV---TIIMTFYLIMGFAFNRRELNELRSTKSSLKVIFD 398
            +ER+ A++  + A+ DYDIVLLQEVW   D+  ++K  I       FSH+F  G IG+GTC+ SK  I+  T+H + L G PQ I HGDW+A KGLG+  + I+  ++ V++SH HAEY    + YL HRV  ALE++ WI+L SA ADL I+ GDFN+EP   P  +++ +  L+D+W   +G    E  GA   +Y           SF P  +    P+G+RID+IM++ G         C  P   R+PGK+ SYSDHE V +T  + ++ ++ +  +   K     +  S    ++++ LE  ++ +   S     ++ +   ++                     L  +   L+V   ++  T Y ++     R+E N L+ST+ SL V+ +
Sbjct:  532 KERIAAIASRI-AQGDYDIVLLQEVWCVTDFDIIRKEAIQC---LPFSHFFHIGAIGSGTCVLSKFPIQDATYHEYSLCGNPQDILHGDWYAGKGLGVCRVKINDLDVRVFISHLHAEYLSSKEAYLAHRVAQALEASLWIKLASAGADLVIFGGDFNSEPGDAPYNIIRAVIPLEDAWIVANGEAGGESCGAEKNSYTGLHNMLPGSCSFKPSELA-LIPKGQRIDFIMFKPGHGLSCKAISCTQPFPDRIPGKSVSYSDHEGVAATLMVEKQHNATQ-DITSKKLPTKKEVLSSSLTIISDRLEKAYKEQVFFSALAVLFVSLIIVMISSNY-----------------LPSWLASLLVSLCSVAATVYTLVAGVHMRKERNALKSTRQSLLVLLE 1656          

BLAST of EMLSAG00000000343 vs. C. finmarchicus
Match: gi|592848877|gb|GAXK01108667.1| (TSA: Calanus finmarchicus comp297681_c2_seq1 transcribed RNA sequence)

HSP 1 Score: 152.525 bits (384), Expect = 7.980e-39
Identity = 92/274 (33.58%), Postives = 143/274 (52.19%), Query Frame = 0

Query:    6 PSVLPRSCRERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASA--DLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRK 277
            P++   +  ER  A+  +L A E+YD V LQEVW ++DY  L K  +LS     +S+YF  G IG+GTCIFS ++I      +F +NG+P  +  GD  A  G+G   + +   ++ + V+H+HAEY  E   +   R   A E+  +++L +     DL I AGDFN+ P ++P ++L   + L+D W+   G      G    +Y     PE+          +DY+  + G++  V      LPL   +PG  +SYSDHEA+E+   I  K
Sbjct: 2090 PTISSPNRAERFHAIGEFL-ASENYDFVFLQEVWDEQDYLNLTK--VLSKN-LPYSYYFKTGTIGSGTCIFSSAQIDQVFDRTFSINGFPHQVWRGDALAGSGIGAVQVTLADKKVLLCVTHFHAEYYGE---FQTDRATQAWEARNFVKLMAQGDKFDLLILAGDFNSLPGELPHRILT--SCLRDCWQ---GDYEVTFGNMKNSYAEKEAPET----------LDYVFVKEGSNVKVTVNKTCLPLENAIPGSKHSYSDHEALETELLIESK 2845          

BLAST of EMLSAG00000000343 vs. C. finmarchicus
Match: gi|592899481|gb|GAXK01058894.1| (TSA: Calanus finmarchicus comp126177_c0_seq1 transcribed RNA sequence)

HSP 1 Score: 85.5001 bits (210), Expect = 5.173e-17
Identity = 89/283 (31.45%), Postives = 133/283 (47.00%), Query Frame = 0

Query:   16 RVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHY---------FDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEP---DKVPLKLLKYITSLKDSWEEVHGSNA-NEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPL--SKRVPGKNYSYSDHEAVESTFRIRRKMDSNKC 283
            R++AL   L  +  YDIVLLQE+W  EDY     ++I S  P+  +HY         F   +  +G  I SK  I       F   G       G+ F  KG+G+A +      I V+ +H    Y    D  L  R + A+E+   I    + AD+ I+ GD N  P    + P  +L+  T +KDS  E H S + +   AT     N++T +SV    PE  RIDY+MY+A +  D+   D  +PL  ++   G+  S SDHEA+ S + +  +   N+ 
Sbjct:  773 RIKALREEL-LQGKYDIVLLQELWYREDY-----SIIASSMPY-ITHYESINSGCSSFILPLGCSGLTILSKHPIVEVRLVPFTHRGSFWRFD-GEIFVRKGVGMARIRWGDKTIDVFTTHL-VSYTKATDNKLT-RYLQAMETVSLI--ARSDADIAIFGGDLNAGPIESPRHPYGMLR--TVMKDSLIEKHPSASFHPVFATFGNAENTYTHKSV----PE--RIDYLMYRAKSHLDMKVLDFTMPLFMTRNSEGQTVSLSDHEALLSVYSLEERYTFNQS 1561          

BLAST of EMLSAG00000000343 vs. C. finmarchicus
Match: gi|592777551|gb|GAXK01177017.1| (TSA: Calanus finmarchicus comp140614_c0_seq2 transcribed RNA sequence)

HSP 1 Score: 65.0846 bits (157), Expect = 1.629e-10
Identity = 84/290 (28.97%), Postives = 125/290 (43.10%), Query Frame = 0

Query:   14 RERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFD-----NGIIG----TGTCIFSKSRIRFTTFHSFGLNG-YPQSISHGDWFAAKGLGIAVLYID-GFEIHVYVSHYHAE------YNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEP----DKVPLKLLKYITSLKDSWEEVHGSNA---NEEGATCETYYNSFTPESVKQACPEGKR----IDYIMYQAGADTDVV--TKDCILPL---SKRVPGKNYSYSDHEAVES 270
             ER+ A+   LS  E YDIV+L+E+W   D+ T+KK+L   G  +  + Y D     +G I     +G  + SK   +   F  F   G + Q  S G++FA KG+G   L    G  + V V+H  +E         + D  L H             +  +SAD  I  GDFN  P    DK   K+ + +T   D+++E+  S     + E AT     N++T          GK+     DYI ++   +   +  TK   LP     + +     S SDHEAV S
Sbjct:  418 EERMTAIGKLLSQSE-YDIVMLEELWMRPDHDTIKKSL---GPEYYMTEYDDLTTSCDGKIWPWGCSGLAVISKFPFQQKNFSRFSQQGTFGQIFSDGEYFAGKGVGKVTLSPKPGMLLDVVVTHTISEDSNAQIREGQADELLAH-------------VKKSSADFVILGGDFNASPMMEGDKTYHKIKEVMT---DAFQEIMASIKAWLDPEYATFGHLRNTYT---------GGKKDPTIYDYIFHKRNTEEPAMIWTKWFFLPFLNTIRSMDNSTISLSDHEAVTS 1200          

BLAST of EMLSAG00000000343 vs. C. finmarchicus
Match: gi|592777552|gb|GAXK01177016.1| (TSA: Calanus finmarchicus comp140614_c0_seq1 transcribed RNA sequence)

HSP 1 Score: 65.0846 bits (157), Expect = 1.637e-10
Identity = 84/290 (28.97%), Postives = 125/290 (43.10%), Query Frame = 0

Query:   14 RERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFD-----NGIIG----TGTCIFSKSRIRFTTFHSFGLNG-YPQSISHGDWFAAKGLGIAVLYID-GFEIHVYVSHYHAE------YNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEP----DKVPLKLLKYITSLKDSWEEVHGSNA---NEEGATCETYYNSFTPESVKQACPEGKR----IDYIMYQAGADTDVV--TKDCILPL---SKRVPGKNYSYSDHEAVES 270
             ER+ A+   LS  E YDIV+L+E+W   D+ T+KK+L   G  +  + Y D     +G I     +G  + SK   +   F  F   G + Q  S G++FA KG+G   L    G  + V V+H  +E         + D  L H             +  +SAD  I  GDFN  P    DK   K+ + +T   D+++E+  S     + E AT     N++T          GK+     DYI ++   +   +  TK   LP     + +     S SDHEAV S
Sbjct:  418 EERMTAIGKLLSQSE-YDIVMLEELWMRPDHDTIKKSL---GPEYYMTEYDDLTTSCDGKIWPWGCSGLAVISKFPFQQKNFSRFSQQGTFGQIFSDGEYFAGKGVGKVTLSPKPGMLLDVVVTHTISEDSNAQIREGQADELLAH-------------VKKSSADFVILGGDFNASPMMEGDKTYHKIKEVMT---DAFQEIMASIKAWLDPEYATFGHLRNTYT---------GGKKDPTIYDYIFHKRNTEEPAMIWTKWFFLPFLNTIRSMDNSTISLSDHEAVTS 1200          

BLAST of EMLSAG00000000343 vs. C. finmarchicus
Match: gi|592791736|gb|GAXK01162832.1| (TSA: Calanus finmarchicus comp784610_c0_seq2 transcribed RNA sequence)

HSP 1 Score: 64.6994 bits (156), Expect = 2.235e-10
Identity = 68/273 (24.91%), Postives = 123/273 (45.05%), Query Frame = 0

Query:   15 ERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNL---ILSGGPFKFSHYFDNGIIG----TGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLG-IAVLYIDGFEIHVYVSHYHA-EYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRI--DYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRR 276
            ER+ A+  Y+    D D+ LLQE+W   D++T+K  L    +       +    +G +     +G  + SK  ++  +F  +  +GY      G+++A KG G + +     + + ++++   A +YN        +R + A E A+   ++ ++AD  I AGDFN +P             LKD+ +E  G     +     TY N     S   +     R+  DY  ++A     V      +P+ K   G  +S+S+HEAV++TF + +
Sbjct:  609 ERMVAIGDYIRNHTDVDLYLLQELWMRPDHQTIKSALPSDYMMTAVGSLAPALCDGRVAPTFCSGLAVVSKYPLKEVSFTEYSAHGY-IFYKDGEYWARKGTGRVRIETAKNYTVDIFLTSTCAFDYNTY------YRQIQAAEFAE--TVSKSTADFVIGAGDFNIDPRTSETTYASVSKVLKDTRKEFLGKEHWLKDPKMATYGNKVNSYSYGAS-----RLVYDYFWHRARHGHSVSVAQFSVPILKTRDG--HSFSNHEAVQATFVLAK 1379          

BLAST of EMLSAG00000000343 vs. C. finmarchicus
Match: gi|592791737|gb|GAXK01162831.1| (TSA: Calanus finmarchicus comp784610_c0_seq1 transcribed RNA sequence)

HSP 1 Score: 64.6994 bits (156), Expect = 2.251e-10
Identity = 68/273 (24.91%), Postives = 123/273 (45.05%), Query Frame = 0

Query:   15 ERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNL---ILSGGPFKFSHYFDNGIIG----TGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLG-IAVLYIDGFEIHVYVSHYHA-EYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRI--DYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRR 276
            ER+ A+  Y+    D D+ LLQE+W   D++T+K  L    +       +    +G +     +G  + SK  ++  +F  +  +GY      G+++A KG G + +     + + ++++   A +YN        +R + A E A+   ++ ++AD  I AGDFN +P             LKD+ +E  G     +     TY N     S   +     R+  DY  ++A     V      +P+ K   G  +S+S+HEAV++TF + +
Sbjct:  630 ERMVAIGDYIRNHTDVDLYLLQELWMRPDHQTIKSALPSDYMMTAVGSLAPALCDGRVAPTFCSGLAVVSKYPLKEVSFTEYSAHGY-IFYKDGEYWARKGTGRVRIETAKNYTVDIFLTSTCAFDYNTY------YRQIQAAEFAE--TVSKSTADFVIGAGDFNIDPRTSETTYASVSKVLKDTRKEFLGKEHWLKDPKMATYGNKVNSYSYGAS-----RLVYDYFWHRARHGHSVSVAQFSVPILKTRDG--HSFSNHEAVQATFVLAK 1400          

BLAST of EMLSAG00000000343 vs. L. salmonis peptides
Match: EMLSAP00000000343 (pep:novel supercontig:LSalAtl2s:LSalAtl2s104:671412:673075:-1 gene:EMLSAG00000000343 transcript:EMLSAT00000000343 description:"maker-LSalAtl2s104-snap-gene-6.30")

HSP 1 Score: 851.277 bits (2198), Expect = 0.000e+0
Identity = 409/409 (100.00%), Postives = 409/409 (100.00%), Query Frame = 0

Query:    1 MNHDRPSVLPRSCRERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSNKCPLVDYKRSLSVKCQSERFEVVTEALEIIHRSEGLVSYNGTKYLMIASGLLILLILSLLPSLIESSIQQYMDLAMFFPRLIVTIIMTFYLIMGFAFNRRELNELRSTKSSLKVIFDLDKLCDESSKL 409
            MNHDRPSVLPRSCRERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSNKCPLVDYKRSLSVKCQSERFEVVTEALEIIHRSEGLVSYNGTKYLMIASGLLILLILSLLPSLIESSIQQYMDLAMFFPRLIVTIIMTFYLIMGFAFNRRELNELRSTKSSLKVIFDLDKLCDESSKL
Sbjct:    1 MNHDRPSVLPRSCRERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSNKCPLVDYKRSLSVKCQSERFEVVTEALEIIHRSEGLVSYNGTKYLMIASGLLILLILSLLPSLIESSIQQYMDLAMFFPRLIVTIIMTFYLIMGFAFNRRELNELRSTKSSLKVIFDLDKLCDESSKL 409          

BLAST of EMLSAG00000000343 vs. L. salmonis peptides
Match: EMLSAP00000008458 (pep:novel supercontig:LSalAtl2s:LSalAtl2s519:4376:14325:1 gene:EMLSAG00000008458 transcript:EMLSAT00000008458 description:"augustus_masked-LSalAtl2s519-processed-gene-0.0")

HSP 1 Score: 80.1073 bits (196), Expect = 9.171e-17
Identity = 76/264 (28.79%), Postives = 112/264 (42.42%), Query Frame = 0

Query:   29 DYDIVLLQEVWTDEDYKTLKKNLILSGGPF-KFSHYFDNGIIGT-------GTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEP---DKVPLKLLKYI--TSLKDSWEEVHGSNANEE-GATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNY--SYSDHEAVESTFRIRR 276
            +YDIVLLQEVW  +DY  L+  L     P+  +    +    GT       G  I SK  ++    + F   G   +   G+ F  KG+  A +  +GF + V+ +H  +  N  N      R + ALE+ + I+  ++ AD+ ++ GD NT P    + P  +L  +   SL D +     S      G    TY   F PE          RIDY+MY       + T D  +P    V    Y  S SDHE +   F + R
Sbjct:   62 NYDIVLLQEVWLRKDYDVLRPAL-----PYVTYYQTLNGNCFGTFLPLGCSGLTILSKHPMQDAKMYPFQFKGTFWNFD-GEVFVGKGVAKARILWNGFTVDVFTTHLISYTNHPNQDNAKFRYMQALETVRHIR--NSDADIKLFGGDLNTLPITDSREPYGILSTVLTDSLIDKFPRASFSPYYSTFGNKKNTYTRDFVPE----------RIDYLMYANSPKIKMKTFDYHVPNFYTVSSHGYKISLSDHEPIVGVFAVER 307          

BLAST of EMLSAG00000000343 vs. L. salmonis peptides
Match: EMLSAP00000012239 (pep:novel supercontig:LSalAtl2s:LSalAtl2s890:157027:158965:1 gene:EMLSAG00000012239 transcript:EMLSAT00000012239 description:"maker-LSalAtl2s890-augustus-gene-0.11")

HSP 1 Score: 55.8398 bits (133), Expect = 8.074e-9
Identity = 68/291 (23.37%), Postives = 109/291 (37.46%), Query Frame = 0

Query:   15 ERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHY--FDNGIIG-------TGTCIFSKSRIRFTTFHSFGLNGY-PQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQW----IQLTSAS-----------ADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQA-GADTDVVTKDCILPLSKRV--PGKNYSYSDHEAVESTFRIRRK 277
            ER+  ++  L     +D+V  QE+W   D+ T++  L    G +  + +   +N  +        +G  + SK       FH++  +G+  +    G+ F  KG+G   L + G              N   D +L H +  A     +    I+L   S           AD+ I  GD N  PD  P + +K      D ++ +             TY N     SV    P     D+I Y+    D    T    +P+   +   GK  S SDHE + +T   RRK
Sbjct:   77 ERILKIAEMLRKDPQFDVVFFQELWMPADHATIELEL---NGDYSMTSFDSMNNDCMHLTAPFQCSGLAVLSKYPFHEVEFHAYNESGHSSEEFIDGENFVNKGVGRVRLLLPG--------------NTTADFFLTHTIADAPPGKSYTNEDIRLNQVSELVNNGVKKSTADIVILGGDLNASPDSKPYQFIKRCMRXLDIFKILKAL----FDPVISTYANPKNTWSVNITDP--IMYDHIFYKVNNPDYLAWTNIFSVPIFHFLDDSGKKKSVSDHEGIIATLYYRRK 344          

BLAST of EMLSAG00000000343 vs. SwissProt
Match: gi|32172461|sp|Q9VZS6.2|NSMA_DROME (RecName: Full=Putative neutral sphingomyelinase)

HSP 1 Score: 189.889 bits (481), Expect = 1.244e-54
Identity = 102/292 (34.93%), Postives = 163/292 (55.82%), Query Frame = 0

Query:   14 RERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSNKCPLVDYKRSLSVKCQSERFEVVT 305
            R R+ A+   L++ + YDIV LQEVW  ED + L+K    +      SHYF +G++G G  + SK  I  T FH++ +NGY   I H DWF  KG+G+  + + G  +H+Y +H HAEY+  ND Y  HRV+ A ++AQ+I+ T  ++ L I AGD N +P  +  K+L Y + + DS +       ++   T E  +NS+T +  ++  P G RID+I  + G   +    +  LP  +RVPG+ +S+SDHEAV +  ++ +    ++ P+     ++ V C  E  E  +
Sbjct:   24 RPRIDAICKELASGK-YDIVSLQEVWAQEDSELLQKG---TEAVLPHSHYFHSGVMGAGLLVLSKYPILGTLFHAWSVNGYFHRIQHADWFGGKGVGLCRILVGGQMVHLYNAHLHAEYDNANDEYKTHRVIQAFDTAQFIEATRGNSALQILAGDLNAQPQDISYKVLLYTSKMLDSCD-------SDSFRTNECEHNSYTSKQARERNPLGIRIDHIFVRGGDHVNAEIAEYKLPFPERVPGEKFSFSDHEAVMAKLKLFKLEPRSEEPVA----TIEVNCLVEDGETCS 300          

BLAST of EMLSAG00000000343 vs. SwissProt
Match: gi|160332206|sp|O60906.2|NSMA_HUMAN (RecName: Full=Sphingomyelin phosphodiesterase 2; AltName: Full=Lyso-platelet-activating factor-phospholipase C; Short=Lyso-PAF-PLC; AltName: Full=Neutral sphingomyelinase; Short=N-SMase; Short=nSMase)

HSP 1 Score: 186.037 bits (471), Expect = 2.971e-53
Identity = 100/261 (38.31%), Postives = 155/261 (59.39%), Query Frame = 0

Query:   15 ERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIR 275
            +R++ L  +L+ +E +D+ LL+EVW+++D++ L++ L  +   +  +H+F +GIIG+G C+FSK  I+  T H + LNGYP  I HGDWF+ K +G+ VL++ G  ++ YV+H HAEYN + DIYL HRV  A E AQ+I  TS  AD+ +  GD N  P+ +   LLK  T L D++ E      +EEG T     N +  +   +  P G RIDY++Y+A +   +  K      +   P +    SDHEA+ +T  +R
Sbjct:   28 DRMRRLGDFLN-QESFDLALLEEVWSEQDFQYLRQKLSPT---YPAAHHFRSGIIGSGLCVFSKHPIQELTQHIYTLNGYPYMIHHGDWFSGKAVGLLVLHLSGMVLNAYVTHLHAEYNRQKDIYLAHRVAQAWELAQFIHHTSKKADVVLLCGDLNMHPEDLGCCLLKEWTGLHDAYLETRDFKGSEEGNTM-VPKNCYVSQQELKPFPFGVRIDYVLYKAVSGFYISCKS-FETTTGFDPHRGTPLSDHEALMATLFVR 282          

BLAST of EMLSAG00000000343 vs. SwissProt
Match: gi|20138814|sp|Q9ET64.1|NSMA_RAT (RecName: Full=Sphingomyelin phosphodiesterase 2; AltName: Full=Lyso-platelet-activating factor-phospholipase C; Short=Lyso-PAF-PLC; AltName: Full=Neutral sphingomyelinase; Short=N-SMase; Short=nSMase)

HSP 1 Score: 179.874 bits (455), Expect = 6.070e-51
Identity = 95/261 (36.40%), Postives = 151/261 (57.85%), Query Frame = 0

Query:   15 ERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIR 275
            +R++ L  +L+  E +D+ LL+EVW+++D++ LK+ L L+   +  +HYF +GIIG+G C+FS+  I+    H + LNGYP    HGDWF  K +G+ VL++ G  ++ YV+H HAEY+ + DIY  HRV  A E AQ+I  TS  A++ +  GD N  P  +   LLK  T L+D++ E      +E+G T     N +  +      P G RIDY++Y+A +   +  K  +   +   P     +SDHEA+ +T  ++
Sbjct:   28 DRMKRLGDFLNL-ESFDLALLEEVWSEQDFQYLKQKLSLT---YPDAHYFRSGIIGSGLCVFSRHPIQEIVQHVYTLNGYPYKFYHGDWFCGKAVGLLVLHLSGLVLNAYVTHLHAEYSRQKDIYFAHRVAQAWELAQFIHHTSKKANVVLLCGDLNMHPKDLGCCLLKEWTGLRDAFVETEDFKGSEDGCT-MVPKNCYVSQQDLGPFPFGVRIDYVLYKAVSGFHICCKT-LKTTTGCDPHNGTPFSDHEALMATLCVK 282          

BLAST of EMLSAG00000000343 vs. SwissProt
Match: gi|20138887|sp|O70572.1|NSMA_MOUSE (RecName: Full=Sphingomyelin phosphodiesterase 2; AltName: Full=Lyso-platelet-activating factor-phospholipase C; Short=Lyso-PAF-PLC; AltName: Full=Neutral sphingomyelinase; Short=N-SMase; Short=nSMase)

HSP 1 Score: 179.104 bits (453), Expect = 8.454e-51
Identity = 94/261 (36.02%), Postives = 153/261 (58.62%), Query Frame = 0

Query:   15 ERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIR 275
            +R++ L  +L+  E++D+ LL+EVW+++D++ L++ L L+   +  +HYF +G+IG+G C+FSK  I+    H + LNGYP    HGDWF  K +G+ VL + G  ++ YV+H HAEY+ + DIY  HRV  A E AQ+I  TS +AD+ +  GD N  P  +   LLK  T L D++ E      +++G T     N +  +      P G RIDY++Y+A ++  V  +  +   +   P  +  +SDHEA+ +T  ++
Sbjct:   28 DRMKRLGDFLNL-ENFDLALLEEVWSEQDFQYLRQRLSLT---YPDAHYFRSGMIGSGLCVFSKHPIQEIFQHVYSLNGYPYMFHHGDWFCGKSVGLLVLRLSGLVLNAYVTHLHAEYSRQKDIYFAHRVAQAWELAQFIHHTSKNADVVLLCGDLNMHPKDLGCCLLKEWTGLHDAFVETEDFKGSDDGCT-MVPKNCYVSQQDLGPFPSGIRIDYVLYKAVSEFHVCCET-LKTTTGCDPHSDKPFSDHEALMATLYVK 282          

BLAST of EMLSAG00000000343 vs. SwissProt
Match: gi|33302616|sp|O45870.2|NSMA_CAEEL (RecName: Full=Putative neutral sphingomyelinase)

HSP 1 Score: 176.022 bits (445), Expect = 2.337e-49
Identity = 119/409 (29.10%), Postives = 202/409 (49.39%), Query Frame = 0

Query:    6 PSVLPRSCRERVQALS---HYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDG-FEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWE---EVHGSNANEE---------GATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSNKCPLVDYKRSLSVKCQSERFEVVTEALEIIHRSEGLVSYNGTKYLMIASGLLILLILSLLPSLIESSIQQYMDLAMFFPRLIVTIIMTFYLIMGFAFNRRELNELRSTKSSLKVIFD 398
            P   P    +RV  L+    Y+   E YDIV LQE+W+  D+  L + +      + + HYF +G  G+G C+FS+  I  T  + + LNG+   I  GDWF  K +G+  + IDG   ++ Y +H HAEY+ END+YL HR   A E AQ+++ T+  AD+ I  GD N EP  +  +L+     L D+W    EV   ++  E         G TC+   N +T  ++K    + KRIDY+++++G   +V  ++C + L++ +PG++ +YSDH  + + F I  +    K          SV        ++ EA+ ++   E     +   + ++A   LIL++ SL   +        M  A+   R  +T++  F++  G      E   L++ K +++ I +
Sbjct:   50 PQPWPIGSTDRVHRLNKIGQYM-IDELYDIVGLQELWSYYDFVRLSEQV---SSVYPYFHYFHSGFTGSGVCVFSRHPIVSTLTNRYSLNGFAHHIHRGDWFGGKVVGLTEIEIDGDLRVNFYTTHLHAEYDRENDLYLPHRTAQAFELAQFVRHTARGADVVIVTGDLNMEPCDLGFRLILSHAKLFDAWRMSHEVENEDSEGELLKFRGIAKGGTCDRPDNCYTKRALKNV-DDSKRIDYMLFKSGR-CNVKLEECEITLNQ-IPGEDLNYSDHVGLRARFTIDDRFRHEK----------SVNTWEPNRPLLIEAIGLVAGGERRARTDRIFFFILAVICLILILGSLFFEVFP------MGFAVL--RFALTVVGVFFVWQGLIGLTLERKALKAAKQAIQQILN 433          

BLAST of EMLSAG00000000343 vs. SwissProt
Match: gi|20138888|sp|O74369.2|CSS1_SCHPO (RecName: Full=Inositol phosphosphingolipids phospholipase C; Short=IPS phospholipase C; Short=IPS-PLC)

HSP 1 Score: 130.183 bits (326), Expect = 1.478e-32
Identity = 107/399 (26.82%), Postives = 182/399 (45.61%), Query Frame = 0

Query:   15 ERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVL-YIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANE---------------EGATCETYYNSFTPESVKQACPE--GKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSNKCPLVDYKRSLSVKCQSERFEVVTEALEIIHRSEGLVSYNGTKYLMIASGLL-ILLILSLLPSLIESSIQQYMDLAMFFPRLIVTIIMTFYLIMGFAFNRRELNELRSTKSSLK 394
            ER++A+   L AK DYDIVLLQEVW+  D++ ++ NL+       +S +F +  +G G  +FSK  I  ++ + + LNG PQ+   GDW+  KG+  A L +  G  I ++ +H HA Y    D YL HR+  A   ++ ++       + I AGDFN +P  VP +++     + D+W  V+                      G TC++  N++      +   +   KR+DY+ +   + +    K+  +   +RVP  + SYSDH A+E+   I+ +      P+ + + S S+   +        A E +H             L IA  L+ I LI+ +  ++          + +FF  ++    +     +G  F R E N L    + LK
Sbjct:   28 ERLKAVGEKL-AKCDYDIVLLQEVWSIYDFQEIR-NLVSCN--LVYSRFFHSAAMGAGLAMFSKFPIIESSMNKYPLNGRPQAFWRGDWYVGKGVATASLQHPSGRIISLFNTHLHAPYGKGADTYLCHRLSQAWYISKLLRAAVQRGHIVIAAGDFNIQPLSVPHEIITSYGLVNDAWLSVYPDQVEHPPNRFSMNDKELVEIAGTTCDSRLNTWRENISSKDMDDFVAKRLDYVFH---SPSTCEAKNAKVVFLERVPKLDCSYSDHFAIETVLSIKLQ----PIPVQETRVSYSIIDDTLGITYQYMARERLHMR-----------LRIAHLLISIPLIIGVHVAIAWCDPAWLKVIILFFTVMLTIAAVVNGFCIGLLFGRWEFNGLLEFVAELK 404          

BLAST of EMLSAG00000000343 vs. SwissProt
Match: gi|731443|sp|P40015.1|ISC1_YEAST (RecName: Full=Inositol phosphosphingolipids phospholipase C; Short=IPS phospholipase C; Short=IPS-PLC; AltName: Full=Neutral sphingomyelinase; Short=N-SMase; Short=nSMase)

HSP 1 Score: 126.331 bits (316), Expect = 6.865e-31
Identity = 107/382 (28.01%), Postives = 168/382 (43.98%), Query Frame = 0

Query:   28 EDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGII-GTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPEND-IYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGA-------------TCETYYNSFTPE-SVKQACPEGKRIDYIMYQAGADTDVV-TKDCILPLSKRVPGKNYSYSDHEAVESTFRI-RRKMDSNKCPLVDYKRSLSVKCQSERFEVVTEALEIIHRSEGLVSYNGTKYLMIASGL-----LILLILSLLPSLIESSIQQYMDLAMFFPRLIVTIIMTFYLIMGFAFNRRELNEL 386
            EDYD++ LQE+W  ED+K L          + +   F +GI+ G G  I SK  I  T  + F +NG P ++  GDW+  K + I VL      I +  SH HA Y  + D  YL HR   A + ++ I+L   +    I  GD N+ P  +P K L     L DSWE++HG       A             TC++  N++  +    +AC    R+DY +     D D + T D  +  ++R+P  + S SDH A   T  I  +  +S     V   ++   +   +R+      +E IH    L +    K+     GL     ++LLI SL+ +   ++   +  +      + V+I  T    + F F R E+  L
Sbjct:   91 EDYDVIALQEIWCVEDWKYLASA---CASKYPYQRLFHSGILTGPGLAILSKVPIESTFLYRFPINGRPSAVFRGDWYVGKSIAITVLNTGTRPIAIMNSHMHAPYAKQGDAAYLCHRSCQAWDFSRLIKLYRQAGYAVIVVGDLNSRPGSLPHKFLTQEAGLVDSWEQLHGKQDLAVIARLSPLQQLLKGCTTCDSLLNTWRAQRQPDEAC----RLDYALI----DPDFLQTVDAGVRFTERIPHLDCSVSDHFAYSCTLNIVPQGTESRPSTSVKRAKTHDRELILQRYSNYETMIECIHTY--LKTAQRQKFF---RGLHFWASILLLIASLVVTTFTANKAGWSSIFWVLFAIAVSISGTIDGAISFLFGRSEIRAL 456          

BLAST of EMLSAG00000000343 vs. Select Arthropod Genomes
Match: EFX80740.1 (hypothetical protein DAPPUDRAFT_318357 [Daphnia pulex])

HSP 1 Score: 237.654 bits (605), Expect = 9.269e-74
Identity = 139/382 (36.39%), Postives = 207/382 (54.19%), Query Frame = 0

Query:   14 RERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRI--RRKMDSNKCPLVDYKRSLSVKCQSERFEVVTEALEIIHRSEGLVSYNGTKYLMIASGLLILLILSLLPSLIESSIQQYMDLAMFFPRLIVTIIMTFYLIMGFAFNRRELNELRSTKSSL 393
            R R+ A+  +L     YD V LQEVW ++D++ + K +   G  F +SHYF +G+IG G CI SK++I    FH++ LNGY   I HGDWF  KG+G+  +   G +I++YV+H HAEYNP +D Y  HRVV A E++Q+I+ T   AD  I  GD NTEP+ +  +L+   TSLKD +  +       EG T ET  NS+T     +ACP GKRID++M  +     + T D  +PL  R+P   +SYSDHEAV + FRI   + + +N+     + +  S+    E  +V   AL  I         N  +   +A G+ ++L+ +L  +   S I  Y          +V +   F LIM   +NR E + + + K ++
Sbjct:   21 RTRIDAIGSHLQLGH-YDFVFLQEVWVEDDFQAIVKQV---GNIFPYSHYFHSGVIGGGICILSKAKIIDVLFHAWSLNGYIHKIQHGDWFGGKGVGLCTVVYHGMKINLYVTHLHAEYNPASDEYCAHRVVQAFETSQFIRYTRNKADFCILGGDLNTEPENLAYRLICDHTSLKDLY--LSTGKPEIEGMTSETPANSYTASESLRACPNGKRIDFVMCSSRKGLQIETIDVNIPLPPRIPNYPFSYSDHEAVCAKFRILETQSVSANQ----KWSKDTSISSLKEALQVCDAALRNI--------ANDRRNYWLAFGIFVVLLAALPFTYDGSRIVHYTLTVTHLLLTLVAV---FCLIMATVWNRIERHGILAGKLAI 381          

BLAST of EMLSAG00000000343 vs. Select Arthropod Genomes
Match: gb|EFA01795.1| (Putative neutral sphingomyelinase-like Protein [Tribolium castaneum])

HSP 1 Score: 230.335 bits (586), Expect = 5.221e-71
Identity = 132/390 (33.85%), Postives = 214/390 (54.87%), Query Frame = 0

Query:    7 SVLPRSCRERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSNKCPLVDYKRSLSVKCQSERFEVVTEALEIIHRSEGLVSYNGTKYL--MIASGLLILLILSLLPSLIESSIQQYMDLAMFFPRLIVTIIMTFYLIMGFAFNRRELNELRSTKSSLK 394
            +V+ ++ R R+QA++  L A   YD+V LQE+W D DY+ ++  +    G   +SHYF +G+ G+G CI S+  +    FH + +NGY   I HGDWF  KG+G+  L ++ + ++VY +H HAEY+   D Y  HRV+ + ++AQ+IQ+TS  ADL + AGD NTEP  +  +++  +  L D++ E  G       AT E+  NS+TP ++ +    GKRIDYIMY  G+   +  K   LPL  ++PG  YSYSDHEA+ +T  + +             RSL    Q  +  V+ E++EI    + L   N  KYL       L++LL+ +L   L        ++      ++++T+ M + L+M   +N+ E + + + K  ++
Sbjct:   14 AVVSKNRRHRMQAIAEKL-ATSQYDVVCLQEIWLDSDYQLIRNKV---SGVLPYSHYFYSGVTGSGVCILSRHPMEDVFFHQWPVNGYIHKIHHGDWFGGKGVGLCKLKVNNYTVNVYSAHLHAEYDRNCDEYQAHRVLQSFDTAQFIQMTSGDADLVVLAGDLNTEPGDLAYRIMLSVPGLVDAFGEA-GETVQNCVATNESLTNSYTPVALLKKNIPGKRIDYIMYHPGSSLQIDLKSYTLPLPHKIPGCAYSYSDHEAIAATLIVTKSE----------IRSLKSD-QHMKKTVLEESIEIC--DDALRGLNNHKYLYWFFTFVLIVLLVTTLATDL---PFGYNLNFIYHILKILITLFMFYTLMMATIWNKIERHAVIAGKLGME 382          

BLAST of EMLSAG00000000343 vs. Select Arthropod Genomes
Match: XP_395633.4 (PREDICTED: putative neutral sphingomyelinase [Apis mellifera])

HSP 1 Score: 228.794 bits (582), Expect = 2.311e-70
Identity = 137/390 (35.13%), Postives = 209/390 (53.59%), Query Frame = 0

Query:    6 PSVLPRSCRERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSNKCPLVDYKRSLSVKCQSERFEVVTEALEIIHRSEGLVSYNGTKYLMIASGLLILLILSLLPSLIESSIQQYMDLAMFFPRLIVTIIMTFYLIMGFAFNRRELNELRSTKSSLKV 395
            P V P     R+ A++    A E+YDI+ LQE+W+  D+K +K     +     +SHYF +G+IG+G CI SK  I+   FH + LNGY   I HGDWF  KG+G+  L I  + ++VY++H HAEYN  ND Y+ HRV+ A ++AQ+I++TS  AD TI  GD NTEP  +  +++  +  L D+      SN++    T E   NS+T        P+GKRID+I+YQ   +  +   +   P   R+P KN+SYSDHEA+ +TF+    +  +K   +D K SL             EA+ I   S   V      YL++   L+I LI S+      +S+   + L +   R+ +T I+ + L M   +N  E N L++    +++
Sbjct:   18 PYVSPNR-SARMTAIADKF-ATENYDIICLQEIWSINDFKMIKAK---TQEQLPYSHYFYSGVIGSGLCILSKFPIKDVIFHKWPLNGYVHKIHHGDWFGGKGVGLCKLQIHNWNVNVYIAHLHAEYNRHNDEYIAHRVLQAFDTAQFIRMTSGGADSTILGGDLNTEPQDLVYRIICGVAGLTDA-----CSNSSSNLGTNECANNSYTNTKHANTFPDGKRIDHILYQGTKNVKIEIINFQHPFPNRIPYKNFSYSDHEAIMATFKF--SIGESKIINIDIKDSLK------------EAINICETSLKNVRRQRFWYLLLGCILIIPLIWSIGLDCSFTSLDVIIGLNI--GRIFLTAILCYTLFMSSIWNSVEKNALKAACLGMEI 381          

BLAST of EMLSAG00000000343 vs. Select Arthropod Genomes
Match: XP_006565412.1 (PREDICTED: putative neutral sphingomyelinase [Apis mellifera])

HSP 1 Score: 228.794 bits (582), Expect = 2.311e-70
Identity = 137/390 (35.13%), Postives = 209/390 (53.59%), Query Frame = 0

Query:    6 PSVLPRSCRERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSNKCPLVDYKRSLSVKCQSERFEVVTEALEIIHRSEGLVSYNGTKYLMIASGLLILLILSLLPSLIESSIQQYMDLAMFFPRLIVTIIMTFYLIMGFAFNRRELNELRSTKSSLKV 395
            P V P     R+ A++    A E+YDI+ LQE+W+  D+K +K     +     +SHYF +G+IG+G CI SK  I+   FH + LNGY   I HGDWF  KG+G+  L I  + ++VY++H HAEYN  ND Y+ HRV+ A ++AQ+I++TS  AD TI  GD NTEP  +  +++  +  L D+      SN++    T E   NS+T        P+GKRID+I+YQ   +  +   +   P   R+P KN+SYSDHEA+ +TF+    +  +K   +D K SL             EA+ I   S   V      YL++   L+I LI S+      +S+   + L +   R+ +T I+ + L M   +N  E N L++    +++
Sbjct:   18 PYVSPNR-SARMTAIADKF-ATENYDIICLQEIWSINDFKMIKAK---TQEQLPYSHYFYSGVIGSGLCILSKFPIKDVIFHKWPLNGYVHKIHHGDWFGGKGVGLCKLQIHNWNVNVYIAHLHAEYNRHNDEYIAHRVLQAFDTAQFIRMTSGGADSTILGGDLNTEPQDLVYRIICGVAGLTDA-----CSNSSSNLGTNECANNSYTNTKHANTFPDGKRIDHILYQGTKNVKIEIINFQHPFPNRIPYKNFSYSDHEAIMATFKF--SIGESKIINIDIKDSLK------------EAINICETSLKNVRRQRFWYLLLGCILIIPLIWSIGLDCSFTSLDVIIGLNI--GRIFLTAILCYTLFMSSIWNSVEKNALKAACLGMEI 381          

BLAST of EMLSAG00000000343 vs. Select Arthropod Genomes
Match: EDO63591.1 (AGAP008053-PA, partial [Anopheles gambiae str. PEST])

HSP 1 Score: 218.009 bits (554), Expect = 5.515e-66
Identity = 129/392 (32.91%), Postives = 214/392 (54.59%), Query Frame = 0

Query:   16 RVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSNKCPLVDYKRSLSVK----CQSERFE--------VVTEALEIIHRSEGLVSYNGTKYLMIASGLLILLILSLLPSLIESSIQQYMDLAMFFPRLIVTIIMTFYLIMGFAFNRRELNELRSTKSSLKV 395
            RV+A+   L A  +YDIV LQEVW+D DY+ LK+ +        F HYF +G++G+G  I S+  I    FH++ +NGY   I HGDWF  KG+G+A + ++   +HVYV+H HAEYN + D Y+ HRV+ A ++AQ+I+ T   + L + AGD NTEP  +  ++L   + LKDS++     +      T E + NS+T     +  P GKRIDYI+Y+ G   +    +  LPL +RVPG+ +SYSDHEAV +   +++   ++    +    S  V+    C  E  E         + E++ I + S   +  +   Y ++A G++I LI      ++E      + +A    + ++  ++ F+++M   +N  E + + + K S+++
Sbjct:   23 RVKAIGDVL-ASGNYDIVSLQEVWSDSDYQYLKQRV---ENVLPFCHYFYSGVVGSGLAILSRYPIVAAFFHAWSVNGYIHRIQHGDWFGGKGVGMAKISVNDQLVHVYVAHLHAEYNRQCDDYMAHRVIQAHDTAQFIESTRGQSVLQVLAGDLNTEPGDLAYRVLVTSSKLKDSYDR---KSIGSGVGTNECHTNSYTDPLAAKQLPNGKRIDYILYRIGDHYEGRLLEHRLPLPERVPGQTFSYSDHEAVYAKLILKKSSSTSTIQNLIACNSGKVREEDSCSRESREETDREAVLSLRESVAICNESLKQLESHRRSYTLMAIGVIIALIY-----MLELQAPYGLKIAFLVLKFLLCAVIIFFVVMATIWNVMEKHGILAGKLSMEI 402          

BLAST of EMLSAG00000000343 vs. Select Arthropod Genomes
Match: gb|EEC04339.1| (conserved hypothetical protein, partial [Ixodes scapularis])

HSP 1 Score: 214.157 bits (544), Expect = 3.200e-64
Identity = 132/420 (31.43%), Postives = 205/420 (48.81%), Query Frame = 0

Query:   15 ERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRI-------------RRK----MDSNKCPLVDYKRSLSVKCQS---------------------ERFEVVTEALEIIHRSEGLVSYNGTKYLMIASGLLILLILSLLPSLIESSIQQYMDLAMFFPRLIVTIIMTFYLIMGFAFNRRELNELRSTKSSLKVI 396
            ER+ A+++YLS+  D D V LQE+W+  DYK ++     +      +HYF +G++G+G CI SKS I  T    + LNGY     HGDWF  K +G+  +   G  I++YV+H HAEYN + DIYL HR+  A E +Q+++LTS + DL I AGDFNTEP   P  ++ + T L+D+++ +        GATC    N +T    K  CP GKRIDY+M++ G       K C  P  K   G     SDHE VE   R+             RR+    +    C  V   +SL + C +                          +T   E + RS   + Y    + +++   ++ ++ + LP      + +  D  +   R + T+++ F L+MGF +N  E + L     S++++
Sbjct:   23 ERMTAIANYLSS-SDLDFVFLQEIWSQRDYKRIRSK---TRNNLPHAHYFHSGVLGSGVCILSKSPIADTGMLKYNLNGYAHKFYHGDWFGGKVVGLCKVNHRGLLINLYVTHLHAEYNRQRDIYLSHRICQAFEMSQYVKLTSETCDLAIVAGDFNTEPLDPPYNIILHNTCLEDAFDSL------CVGATCGHPDNHYTSAYDKHTCPTGKRIDYVMFKVGRGVVANCKVCKNPRLKTTSG--LPLSDHEPVEVVMRVTKSSQRESEYQVSRRRSILHLRRAFCRNVATPQSLCIVCLAVASAGLNGGALSPNKSDVSTPAHLNALTRGQEQLMRSLDRL-YMDRVFYIVSCCFMVCVLAATLP----MELPEGFDWVLVVCRTVATLLLGFCLVMGFFWNAMEKSSLLEAHKSMRLL 425          

BLAST of EMLSAG00000000343 vs. Select Arthropod Genomes
Match: gb|KFM82038.1| (Sphingomyelin phosphodiesterase 2, partial [Stegodyphus mimosarum])

HSP 1 Score: 206.453 bits (524), Expect = 7.136e-63
Identity = 107/276 (38.77%), Postives = 162/276 (58.70%), Query Frame = 0

Query:    9 LPRSCRERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGS---NANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSN 281
            + R  ++R++A++ ++ A  +YD V LQEVW+++D++ + K    +     FSHYF +G++G+G CI SKS I       + LNGY   I HGDW+  K +G+  +   G +I++YV+H HAEY+  +D YL HRV  A E +Q++QLTS +ADL+I AGDFNTEP  +P K++ +     D++         N +    TC    N +T       CP GKRIDYI+Y+ G  T      C  PL K +PG +  YSDHEAV +T  + + +++ 
Sbjct:   20 ISRHRKQRMEAIASHI-ASSNYDFVFLQEVWSEKDFQLICKK---AAAVLPFSHYFYSGVLGSGVCILSKSCIVDVAQFQYALNGYAHKILHGDWYGGKVVGLCKVIHHGLKINLYVTHLHAEYDAFHDQYLPHRVAQAFEFSQFVQLTSETADLSIVAGDFNTEPTDLPYKVIIHNAGCIDTYLSQRNPDLLNCSTIKTTCGHPDNLYTSRKEINRCPTGKRIDYILYKCGTGTHAECLTCDTPLGK-IPGSSIPYSDHEAVVATLHVFKSIEAQ 290          

BLAST of EMLSAG00000000343 vs. Select Arthropod Genomes
Match: EEB11492.1 (sphingomyelin phosphodiesterase, putative [Pediculus humanus corporis])

HSP 1 Score: 205.297 bits (521), Expect = 9.423e-61
Identity = 107/254 (42.13%), Postives = 150/254 (59.06%), Query Frame = 0

Query:   16 RVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVE 269
            R+ A++ YLS+  D DIV LQE+W+ +DY  + K   L      +SHYF++ IIG+G CIFSK  I    FH + +NGY   I  GDW A KG+  A + I    ++VY +H HAEYN     YL HRV+ A +++Q+I+LT    DL + AGD NTEPD + +K+L     L D +           G T E+  NS+ P+S  +  P+GKRIDYI+Y+     +V  ++   PL ++VPG  +SYSDHE VE
Sbjct:   35 RITAIAEYLSS-SDLDIVCLQEIWSKKDYLYISKKCFLQ---LPYSHYFNSFIIGSGLCIFSKHPISDVYFHQWPINGYAHKIHQGDWLAGKGVAFARIKIKDLVVNVYNAHLHAEYNIHGTEYLSHRVLQAFDTSQFIRLTIEDCDLAVLAGDLNTEPDDLAIKILNQNAQLTDCYFVAQKKTLTFFG-TNESTRNSYAPKSEVKRLPQGKRIDYILYRNSRKINVEVQNYQFPLPEKVPGCTHSYSDHEGVE 283          

BLAST of EMLSAG00000000343 vs. Select Arthropod Genomes
Match: AAF47741.2 (uncharacterized protein Dmel_CG12034 [Drosophila melanogaster])

HSP 1 Score: 189.889 bits (481), Expect = 6.028e-55
Identity = 102/292 (34.93%), Postives = 163/292 (55.82%), Query Frame = 0

Query:   14 RERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSNKCPLVDYKRSLSVKCQSERFEVVT 305
            R R+ A+   L++ + YDIV LQEVW  ED + L+K    +      SHYF +G++G G  + SK  I  T FH++ +NGY   I H DWF  KG+G+  + + G  +H+Y +H HAEY+  ND Y  HRV+ A ++AQ+I+ T  ++ L I AGD N +P  +  K+L Y + + DS +       ++   T E  +NS+T +  ++  P G RID+I  + G   +    +  LP  +RVPG+ +S+SDHEAV +  ++ +    ++ P+     ++ V C  E  E  +
Sbjct:   24 RPRIDAICKELASGK-YDIVSLQEVWAQEDSELLQKG---TEAVLPHSHYFHSGVMGAGLLVLSKYPILGTLFHAWSVNGYFHRIQHADWFGGKGVGLCRILVGGQMVHLYNAHLHAEYDNANDEYKTHRVIQAFDTAQFIEATRGNSALQILAGDLNAQPQDISYKVLLYTSKMLDSCD-------SDSFRTNECEHNSYTSKQARERNPLGIRIDHIFVRGGDHVNAEIAEYKLPFPERVPGEKFSFSDHEAVMAKLKLFKLEPRSEEPVA----TIEVNCLVEDGETCS 300          

BLAST of EMLSAG00000000343 vs. Select Arthropod Genomes
Match: gb|KPM09275.1| (neutral sphingomyelinase-like protein [Sarcoptes scabiei])

HSP 1 Score: 108.227 bits (269), Expect = 9.845e-27
Identity = 62/178 (34.83%), Postives = 99/178 (55.62%), Query Frame = 0

Query:   16 RVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNG-IIGT-GTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPEN---DIYLGHRVVHALESAQWIQL------TSASADLTIYAGDFNTEPDKVPLKLL 182
            R++ ++ +L   +DYD+V LQEVW   D++ ++     +   +KF+H F+N  ++GT G  I +K       F+ + +NG P    HGDWF+ KG+  A + + G  +H++ +H HA+Y+      D Y  HR+  A E  ++I L       SAS DL I AGD NT   ++P +LL
Sbjct:   31 RMKLIAQHL-CDQDYDVVFLQEVWIQSDFEYIRTK---TNFKYKFAHIFNNASLLGTSGLVILAKWLPALIYFNPYTINGSPFRPLHGDWFSTKGVAYARIELIGLNLHLFCTHMHAQYDDNEKLIDQYSVHRICQAYELGKFINLMSCNCTNSASKDLIILAGDLNTCSKEIPYRLL 204          

BLAST of EMLSAG00000000343 vs. nr
Match: gi|1080053249|ref|XP_018568210.1| (PREDICTED: putative neutral sphingomyelinase [Anoplophora glabripennis])

HSP 1 Score: 258.07 bits (658), Expect = 6.267e-79
Identity = 143/389 (36.76%), Postives = 231/389 (59.38%), Query Frame = 0

Query:    7 SVLPRSCRERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSNKCPLVDYKRSLSVKCQSERFEVVTEALEIIHRSEGLVSYNGTKYLMIASGLLILLILSLLPSLIESSIQQYMDLAMFFPRLIVTIIMTFYLIMGFAFNRRELNELRSTKSSLKV 395
            +V+ ++ +ER+QA++  L A   YD+V LQEVWTD DY  ++K +    G   FSHYF +G+ G+G CI S+  I  T FH + +NGY   + HGDWF  KG+G+  L I+ F I+VY +H HAEY+ E+D Y  HR++ A ++AQ+I LTS  ADL I AGD NTEP  +  ++   +  L D++ E +    N++ AT E+  NS+TP S+ +    GKRIDYIMY  G+   V  K   LPL  RVP +++SYSDHEA+E+T  I RK   ++   ++ K+            V+ ++L ++  +   ++ +   YL+ +   L+L I  L+ ++++S +     +  +  R ++T++M F +IM   +N+ E + + + K +++V
Sbjct:   18 AVVSKNRKERIQAIAEVL-ATSQYDVVCLQEVWTDRDYNLIRKKV---SGVLPFSHYFYSGVTGSGVCILSRHPIEETFFHQWSVNGYIHKLHHGDWFGGKGVGLCKLKINNFNINVYSAHLHAEYDRESDEYQAHRILQAYDTAQFIMLTSGGADLVILAGDLNTEPGDLAYRVTLCVPGLLDAFTEAN-EVPNDKVATNESLQNSYTPSSLVRKNIPGKRIDYIMYHPGSKIHVDLKKYNLPLPDRVPERSFSYSDHEAIEATLVINRKEIPDRIRDLEQKKI-----------VLEDSLVVLEDALRRLNTHQLIYLIFS---LVLFITLLVSAVLDSPVG--YAILFYVLRALITVLMVFTIIMATIWNKIERHAVLAGKLAIEV 385          

BLAST of EMLSAG00000000343 vs. nr
Match: gi|1061479693|gb|ODM97185.1| (putative neutral sphingomyelinase [Orchesella cincta])

HSP 1 Score: 244.973 bits (624), Expect = 1.465e-72
Identity = 137/378 (36.24%), Postives = 213/378 (56.35%), Query Frame = 0

Query:   16 RVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEV---HGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSNKCPLVDYKRSLSVKCQSERFEVVTEALEIIHRSEGLVSYNGTKYLMIASGLLILLILSLLPSLIESSIQQYMDLAMFFPRLIVTIIMTFYLIMGFAFNRRELNELRSTK 390
            R+ A++  L A   YD V LQEVWT EDY+ +K     +G    +SHYF +G+IG G CIFSKS I+   FH + +NGY   I HGDWF  KG+G+  +   G  I++Y +H HAEY+  ND YL HRV  A ++AQ+I LTS  AD  I  GD NTEP  +  +L+ +   L+D+ EE+     S + E   TCET  NS++  +  +  P GKRIDYI Y+ G++ +V    C      RVPG+ +SYSDHEAV +  ++ +   + K P+++  ++          E + E++EI + +   +  +   Y++++  L + +ILS+  +L    +  Y+   +   R I+ +I  F + M   ++R E++ + S K
Sbjct:  107 RMTAIAEEL-ATGKYDFVFLQEVWTTEDYERIKSR---TGDVLPYSHYFFSGVIGAGICIFSKSPIKSAFFHQWAVNGYIHKIQHGDWFGGKGIGMVEVDHRGLTINLYTTHLHAEYDRTNDEYLAHRVTQAFDTAQFISLTSKHADAVIVGGDLNTEPGDLAYRLIVHTAQLQDACEEIVSKSKSASKELMNTCETARNSYSSPNSLKLNPFGKRIDYIAYKGGSNVNVSALSCETSWPDRVPGQPFSYSDHEAVVTKLKVSKSDTNAKVPVLNEAKT----------ETLEESIEICNLALNHLQTSKNMYILLS--LAMFVILSMTANL---ELTGYLSPVVPILRAIILLIFFFGIFMSVIWHRMEVHGILSGK 465          

BLAST of EMLSAG00000000343 vs. nr
Match: gi|942408373|gb|JAN86116.1| (Neutral sphingomyelinase [Daphnia magna])

HSP 1 Score: 241.891 bits (616), Expect = 2.003e-72
Identity = 140/378 (37.04%), Postives = 206/378 (54.50%), Query Frame = 0

Query:   16 RVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSNKCPLVDYKRSLSVKCQSERFEVVTEALEIIHRSEGLVSYNGTKYLMIASGLLILLILSLLPSLIESSIQQYMDLAMFFPRLIVTIIMTFYLIMGFAFNRRELNELRSTKSSL 393
            R+ A+ ++L +   YD V LQEVW +ED++ +   +         SHYF +G+IG G CI SK++I    FH++ LNGY   I HGDWF  KG+G+  +   G +I++YV+H HAEYNP +D Y  HRVV A E++Q I+ T   AD+ I  GD NTEP  +  +L+   TSL+D +  +     + EG T ET  NS+T      ACP GKRID+IM  +     + T +  +PL  R+PG  +SYSDHEAV + FRI     +    +    + LS+    E  +V   AL  +         N  +   +A GL I+L+++L  S   S I  Y    +    L +T++  F LIM   +NR EL+ + + K ++
Sbjct:   47 RIDAIGNHLQSG-CYDFVFLQEVWVEEDFQLIANKV---ANVMPHSHYFHSGVIGGGICILSKAKIIDVFFHAWSLNGYIHKIQHGDWFGGKGVGLCTVIYHGLKINLYVTHLHAEYNPSSDEYHAHRVVQAFETSQMIRYTRNKADVCILGGDLNTEPGSLAYRLISDHTSLQDLY--LATGKPDSEGTTSETSVNSYTAIESLYACPNGKRIDFIMGSSREGLQIETVNVNIPLPSRIPGYPFSYSDHEAVCAKFRIVEGQSN----VSSQSKELSICSLKEALQVCDSALRNLS--------NDRRNYWLAFGLFIVLLMTLPFSYDGSRIVHY---TLMVTHLFLTLVAVFCLIMATLWNRIELHGILAGKLAI 403          

BLAST of EMLSAG00000000343 vs. nr
Match: gi|1022774071|gb|KZS18109.1| (Neutral sphingomyelinase [Daphnia magna])

HSP 1 Score: 240.736 bits (613), Expect = 2.830e-72
Identity = 140/378 (37.04%), Postives = 206/378 (54.50%), Query Frame = 0

Query:   16 RVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSNKCPLVDYKRSLSVKCQSERFEVVTEALEIIHRSEGLVSYNGTKYLMIASGLLILLILSLLPSLIESSIQQYMDLAMFFPRLIVTIIMTFYLIMGFAFNRRELNELRSTKSSL 393
            R+ A+ ++L +   YD V LQEVW +ED++ +   +         SHYF +G+IG G CI SK++I    FH++ LNGY   I HGDWF  KG+G+  +   G +I++YV+H HAEYNP +D Y  HRVV A E++Q I+ T   AD+ I  GD NTEP  +  +L+   TSL+D +  +     + EG T ET  NS+T      ACP GKRID+IM  +     + T +  +PL  R+PG  +SYSDHEAV + FRI     +    +    + LS+    E  +V   AL  +         N  +   +A GL I+L+++L  S   S I  Y    +    L +T++  F LIM   +NR EL+ + + K ++
Sbjct:   23 RIDAIGNHLQSG-CYDFVFLQEVWVEEDFQLIANKV---ANVMPHSHYFHSGVIGGGICILSKAKIIDVFFHAWSLNGYIHKIQHGDWFGGKGVGLCTVIYHGLKINLYVTHLHAEYNPSSDEYHAHRVVQAFETSQMIRYTRNKADVCILGGDLNTEPGSLAYRLICDHTSLQDLY--LATGKPDSEGTTSETSVNSYTAIESLYACPNGKRIDFIMGSSREGLQIETVNVNIPLPSRIPGYPFSYSDHEAVCAKFRIVEGQSN----VSSQSKELSICSLKEALQVCDSALRNLS--------NDRRNYWLAFGLFIVLLMTLPFSYDGSRIVHY---TLMVTHLFLTLVAVFCLIMATLWNRIELHGILAGKLAI 379          

BLAST of EMLSAG00000000343 vs. nr
Match: gi|780643257|ref|XP_011688531.1| (PREDICTED: putative neutral sphingomyelinase [Wasmannia auropunctata] >gi|780643261|ref|XP_011688532.1| PREDICTED: putative neutral sphingomyelinase [Wasmannia auropunctata])

HSP 1 Score: 239.965 bits (611), Expect = 5.346e-72
Identity = 134/373 (35.92%), Postives = 209/373 (56.03%), Query Frame = 0

Query:   16 RVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSNKCPLVDYKRSLSVKCQSERFEVVTEALEIIHRSEGLVSYNGTKYLMIASGLLILLILSLLPSLIESSIQQYMDLAMFFPRLIVTIIMTFYLIMGFAFNRRELNELRS 388
            R+ A++   +++E YD+V LQEVW+ ED+K +K     +     +SHYF +G+ G+G CI S+  I    FH + LNGY   I HGDWF  KG+G+  + I    ++VY++H HAEYNPEND Y+ HRV+ A ++AQ++++TS  AD  + AGD NTEP  +  K+++ ++SL D+       N++    T E   NS+T   + +  P+GKRID+IMY       V   +   PL  R+P KN+SYSDHEAV +T +     D++K    D   S S+K   E   +   AL+ + R           Y + A  L+I LI S+  + + +S+   +D+ +    + +T I+ + L M   +N  E N L++
Sbjct:   27 RISAIAEKCASRE-YDVVCLQEVWSVEDFKLIKTK---AQEVLPYSHYFHSGVFGSGVCILSRYPIHDVMFHKWPLNGYVHKIHHGDWFGGKGVGLCKIQIRDMNVNVYITHLHAEYNPENDEYMAHRVLQAFDTAQFVRMTSGGADAVVLAGDLNTEPQDLAYKIIRGVSSLTDT-----CPNSSSHIGTNECANNSYTSSKLARTKPDGKRIDHIMYSGSKTVKVEVTNFQHPLPNRIPYKNFSYSDHEAVMATLKF---TDNDKHATDDADVSDSLK---EAVTICENALKSVERQRFW-------YALSACMLIIPLIWSIWMNCMNTSLA--VDIGLNIVCIFLTAILCYTLFMSSIWNSVEKNALKA 375          

BLAST of EMLSAG00000000343 vs. nr
Match: gi|321469761|gb|EFX80740.1| (hypothetical protein DAPPUDRAFT_318357 [Daphnia pulex])

HSP 1 Score: 237.654 bits (605), Expect = 4.535e-71
Identity = 139/382 (36.39%), Postives = 207/382 (54.19%), Query Frame = 0

Query:   14 RERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRI--RRKMDSNKCPLVDYKRSLSVKCQSERFEVVTEALEIIHRSEGLVSYNGTKYLMIASGLLILLILSLLPSLIESSIQQYMDLAMFFPRLIVTIIMTFYLIMGFAFNRRELNELRSTKSSL 393
            R R+ A+  +L     YD V LQEVW ++D++ + K +   G  F +SHYF +G+IG G CI SK++I    FH++ LNGY   I HGDWF  KG+G+  +   G +I++YV+H HAEYNP +D Y  HRVV A E++Q+I+ T   AD  I  GD NTEP+ +  +L+   TSLKD +  +       EG T ET  NS+T     +ACP GKRID++M  +     + T D  +PL  R+P   +SYSDHEAV + FRI   + + +N+     + +  S+    E  +V   AL  I         N  +   +A G+ ++L+ +L  +   S I  Y          +V +   F LIM   +NR E + + + K ++
Sbjct:   21 RTRIDAIGSHLQLGH-YDFVFLQEVWVEDDFQAIVKQV---GNIFPYSHYFHSGVIGGGICILSKAKIIDVLFHAWSLNGYIHKIQHGDWFGGKGVGLCTVVYHGMKINLYVTHLHAEYNPASDEYCAHRVVQAFETSQFIRYTRNKADFCILGGDLNTEPENLAYRLICDHTSLKDLY--LSTGKPEIEGMTSETPANSYTASESLRACPNGKRIDFVMCSSRKGLQIETIDVNIPLPPRIPNYPFSYSDHEAVCAKFRILETQSVSANQ----KWSKDTSISSLKEALQVCDAALRNI--------ANDRRNYWLAFGIFVVLLAALPFTYDGSRIVHYTLTVTHLLLTLVAV---FCLIMATVWNRIERHGILAGKLAI 381          

BLAST of EMLSAG00000000343 vs. nr
Match: gi|1061133695|ref|XP_017891097.1| (PREDICTED: putative neutral sphingomyelinase [Ceratina calcarata])

HSP 1 Score: 237.654 bits (605), Expect = 5.185e-71
Identity = 134/387 (34.63%), Postives = 206/387 (53.23%), Query Frame = 0

Query:    9 LPRSCRERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSNKCPLVDYKRSLSVKCQSERFEVVTEALEIIHRSEGLVSYNGTKYLMIASGLLILLILSLLPSLIESSIQQYMDLAMFFPRLIVTIIMTFYLIMGFAFNRRELNELRSTKSSLKV 395
            + R  + R+ A++   S KE YD++ LQEVW+ +D+K +K     +     +SHYF +G++G+G CI ++  I+   FH + LNGY   + HGDWF  KG+ +  L I   +++VYV H HAEYN +ND Y  HRV+ A ++AQ+++LT   AD  I  GD NTEP+ +  K++  +T L D+      +N      T E   NS+T      ACPEGKRIDYI+Y    + +V       P   RVPGKN+SYSDHEA+ +TFR      S     +D + SL             E + I   +   VS+    YL+ +  L++ L+ S+   L  S       + +   R+ ++ ++ + L M   +N  E N LR+  S +++
Sbjct:   21 VSRDRKARMAAIAEKFS-KESYDVICLQEVWSIDDFKMIKAK---TQEQLPYSHYFYSGVVGSGICILTRFPIKDVMFHKWPLNGYVHKLHHGDWFGGKGVALCRLQIQDMDVNVYVVHLHAEYNRDNDEYAAHRVLQAFDTAQFVRLTCDGADSAILLGDLNTEPNDLAYKIICGVTGLLDACSNTSSTNL----GTHECANNSYTTSKSANACPEGKRIDYILYHGTKNIEVKATSFKHPFPNRVPGKNFSYSDHEAIVATFRF--SAGSTPSANMDVRDSLK------------EGISICETALKSVSWQRYWYLLFSGMLIVPLVWSM--GLDCSVTSADATIGLNVGRVCLSAVLCYALFMSSIWNSVEKNALRAGCSGMEI 383          

BLAST of EMLSAG00000000343 vs. nr
Match: gi|936595406|ref|XP_014211102.1| (PREDICTED: putative neutral sphingomyelinase [Copidosoma floridanum])

HSP 1 Score: 233.417 bits (594), Expect = 1.881e-69
Identity = 141/397 (35.52%), Postives = 211/397 (53.15%), Query Frame = 0

Query:   15 ERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSNKCPLVDYKRSLSVKCQSERFEVVTEALEIIHRSEGLVSYNGTKYLMIASGLLILLILSL-LPSLIESSIQQYMDLAMFFPRLIVTIIMTFYLIMGFAFNRRELNELRSTKSSLKV-IFDLDKLCDESSKL 409
             R+ A++  L++ ED DIV LQEVW+  DY+ +K     +     +SHYF +G++G+G C+FS+  I    FH + LNGY   I HGDWF  KG+G+  L +   ++HVY++H HAEY  END Y  HRV+ A ++AQ+I++T   AD  I  GD NTEP  +  K++  +  L D+  +  GS    E A      NS+T   V +  P GKRIDYI+Y    +  +   D   P   R+P  N+SYSDHEA+ ++ ++ +   S     VD + SL      E   +  +AL  IHR           YL  +  L+I LI S+ L  LI S I   + +     RL +T ++ + L M   +N  E N L++  S++++ +  L K  D +  L
Sbjct:   26 NRMNAIADKLTS-EDCDIVCLQEVWSINDYRLIKGK---TREKLPYSHYFFSGVLGSGVCMFSRYPIDDVIFHKWPLNGYVHKIHHGDWFGGKGVGLCRLKVHNLDVHVYIAHLHAEYCKENDEYTAHRVLQAFDTAQFIRMTKGGADAVILGGDLNTEPQDLAYKIICGVAGLMDACAKKSGSLGTNECAN-----NSYTDLRVAEKEPNGKRIDYILYMGSKNYKIEVNDFSQPFPTRIPDTNFSYSDHEAIMASLKLTKGYQSEDAN-VDIRTSL-----KEAISICEKALHNIHRQR-------LWYLFFSFILIISLIWSMGLDYLISSII---LSIGFNILRLFLTAVLCYTLFMSSLWNSLEKNALKAGCSAMELQLVRLSKNLDNNCNL 397          

BLAST of EMLSAG00000000343 vs. nr
Match: gi|380020011|ref|XP_003693892.1| (PREDICTED: putative neutral sphingomyelinase [Apis florea] >gi|820849060|ref|XP_012342277.1| PREDICTED: putative neutral sphingomyelinase [Apis florea] >gi|820849062|ref|XP_012342278.1| PREDICTED: putative neutral sphingomyelinase [Apis florea])

HSP 1 Score: 231.106 bits (588), Expect = 1.738e-68
Identity = 137/390 (35.13%), Postives = 209/390 (53.59%), Query Frame = 0

Query:    6 PSVLPRSCRERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSNKCPLVDYKRSLSVKCQSERFEVVTEALEIIHRSEGLVSYNGTKYLMIASGLLILLILSLLPSLIESSIQQYMDLAMFFPRLIVTIIMTFYLIMGFAFNRRELNELRSTKSSLKV 395
            P V P     R+ A++    A E+YDI+ LQE+W+  D+K +K     +     +SHYF +G+IG+G CI SK  I+   FH + LNGY   I HGDWF  KG+G+  L I  + ++VY++H HAEYN  ND Y+ HRV+ A ++AQ+I++TS  AD TI  GD NTEP  +  +++  +  L D+      SN++    T E   NS+T        P+GKRID+I+YQ   +  +   +   P   R+P KN+SYSDHEA+ +TF+    +  +K   +D K SL             EA+ I   S   V      YL++   L+I LI S+      +S+   + L +   R+ +T I+ + L M   +N  E N L++    +++
Sbjct:   18 PYVSPNR-NARMTAIADKF-ATENYDIICLQEIWSINDFKMIKAK---TQEQLPYSHYFYSGVIGSGLCILSKFPIKDVIFHKWPLNGYVHKIHHGDWFGGKGVGLCKLQIHNWNVNVYIAHLHAEYNRHNDEYIAHRVLQAFDTAQFIRMTSGGADSTILGGDLNTEPQDLVYRIICGVAGLTDA-----CSNSSSNLGTNECANNSYTNSKHANTLPDGKRIDHILYQGTKNVKIEITNFQHPFPNRIPYKNFSYSDHEAIMATFKF--SIGESKTINIDIKDSLK------------EAINICETSLKNVRRQRFWYLLLGCILIIPLIWSIGLDCSFTSLNVIIGLNI--GRIFLTAILCYTLFMSSIWNSVEKNALKAACLGMEI 381          

BLAST of EMLSAG00000000343 vs. nr
Match: gi|795114309|ref|XP_011882899.1| (PREDICTED: putative neutral sphingomyelinase [Vollenhovia emeryi] >gi|795114316|ref|XP_011882900.1| PREDICTED: putative neutral sphingomyelinase [Vollenhovia emeryi] >gi|795114323|ref|XP_011882901.1| PREDICTED: putative neutral sphingomyelinase [Vollenhovia emeryi])

HSP 1 Score: 230.72 bits (587), Expect = 1.997e-68
Identity = 131/380 (34.47%), Postives = 209/380 (55.00%), Query Frame = 0

Query:   16 RVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVHGSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSNKCPLVDYKRSLSVKCQSERFEVVTEALEIIHRSEGLVSYNGTKYLMIASGLLILLILSLLPSLIESSIQQYMDLAMFFPRLIVTIIMTFYLIMGFAFNRRELNELRSTKSSLKV 395
            R+ A++   +++E YDI+ LQEVW+ ED+K +K     +     +SHYF +G+ G+G C+ S+  I    FH + LNGY   I HGDWF  KG+G+  + I    ++VY++H HAEYN END Y+ HRV+ A ++AQ++++TS  AD  + AGD NTEP  +  ++++ +  L D+       N+     T E   NS+T   + +  P+GKRID+IMY       V   +   PL  RVP KN+SYSDHEAV +T     K   +K    D   + S+K   E  E+   AL+ + R           Y + A  L++ LI S+  + +  SI   +D+ +    +++T I+ + L M   +N  E N L++ + ++++
Sbjct:   27 RISAIADKCASRE-YDIICLQEVWSVEDFKLIKTK---AQEVLPYSHYFHSGVFGSGVCVLSRYPIHDVMFHKWPLNGYVHKIHHGDWFGGKGVGLCKINIRNMNVNVYITHLHAEYNRENDEYMAHRVLQAFDTAQFVRMTSGGADAVVLAGDLNTEPQDLAYRIIQGVAGLADA-----CPNSASHRGTNECANNSYTSSKLARTKPDGKRIDHIMYLGSKTVKVEVTNFQHPLPNRVPYKNFSYSDHEAVMATL----KFTDDKHVTNDLDVTDSLK---EATEICDNALKSVQRQRFW-------YGLSACILIVPLIWSIWLNCMNMSIA--VDIGLNIVCILLTAILCYTLFMSSIWNSVEKNALKAGRLAIEI 381          

BLAST of EMLSAG00000000343 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold280_size224562-snap-gene-1.16 (protein:Tk08833 transcript:maker-scaffold280_size224562-snap-gene-1.16-mRNA-1 annotation:"neutral sphingomyelinase")

HSP 1 Score: 130.183 bits (326), Expect = 3.683e-34
Identity = 101/362 (27.90%), Postives = 165/362 (45.58%), Query Frame = 0

Query:   14 RERVQALSHYLSAKED-YDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHY--FDNGIIGTGTCIFSKSRIRFTTFHSFGLNGYPQSISHGDWFAAKGLGIAVLYI-DGFEIHVYVSHYHAEYNP---------ENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKVPLKLLKYITSLKDSWEEVH--GSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVVTKDCILPLSKRVPGKNYSYSDHEAVESTFRIRRKMDSNKCPLVDYKRSLSVKCQSERFEVV-TEALEIIHRSEGLVSYNGTKYLMIASGLLILLILSLLPSLIESSIQQYMDLAMFF 359
            R R+ AL+ +L    + YD V LQE+W   D   +K +   +       H+  F  G+IGTG  + S+  +    +  F +NG+   I  GD     G+G A   + +G  I +  SHYHAEY+           +D +L  RV  ALE+ + I   S +AD+ IYAGD NTEP  +P ++L  +  L+D+ +  H  G + N  G     +Y+     +V         IDYI+ ++ A+  + +  C  PL +R+  +  SYS+HE V +TF I        C       S   K +    E++ +E +  +       ++     + +    L+LL  SL       +  Q +D+ + F
Sbjct:   23 RTRIGALARHLEQSGNRYDFVFLQELWLQSDRDEIKASCSET-----LPHFLEFHGGVIGTGLLMLSRYPLLKPAYSMFSMNGFKHQIWLGDSLCGSGIGTAWTTLPNGLSILLSTSHYHAEYDRLAHNWINSRSHDEFLVDRVSQALEAQEVIAAQSEAADVVIYAGDLNTEPGDLPHRILTTLGGLQDTRDPNHVPGPSFNLAG----NFYSVSKERAVT--------IDYILAKSSAEKTIKSSACRNPLPERIQDEVISYSNHEPVWATFEIGEATKEEDC-------SSGPKNEPSEPEILRSEIMSFLASERAKATWRQRGLIFLTMSFLVLLSTSL------RTWNQVVDVGLGF 354          

BLAST of EMLSAG00000000343 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold478_size161223-snap-gene-0.27 (protein:Tk02255 transcript:maker-scaffold478_size161223-snap-gene-0.27-mRNA-1 annotation:"neutral sphingomyelinase")

HSP 1 Score: 72.4034 bits (176), Expect = 4.591e-14
Identity = 81/295 (27.46%), Postives = 132/295 (44.75%), Query Frame = 0

Query:   15 ERVQALSHYLSAKEDYDIVLLQEVWTDEDYKTLKKNLILSGGPFKFSHYFDNGI--IGTGTC-------------IFSKSRIRFTTFHSFGLNGYP-QSISHGDWFAAKGLG-IAVLYIDGFEIHVYVSHYHAEYNPENDIYLGHRVVHALESAQWIQLTSASADLTIYAGDFNTEPDKV---PLKLLKYITSLKDSWEEVH-------GSNANEEGATCETYYNSFTPESVKQACPEGKRIDYIMYQAGADTDVV---TKDCILPLSKRVPGKNY--SYSDHEAVESTFRIRRK 277
            ER++A++  LS + D+DI LLQE+W + D+ TL   L         S Y+  G   +  GTC             I SK       F+S+  +G P +S    +W A KG+G + +  + G  + V+V+H  A+ +P +     +  +  ++      +T + AD+ +  GDFN  P++    P  ++K    +++  EEV               G    T+ N +TP             DYI +    D +VV   T    LP  K    K++  S+SDHEAVE+T  + +K
Sbjct:  133 ERMKAIAQELS-RGDHDIYLLQELWMNPDWNTLHAALP--------SGYYMTGFRDLALGTCDGRVGPEFCSGLTIVSKYPFLEKEFNSYTYHGDPLKSWIDAEWLARKGVGRVRIEPLPGMVVDVFVTHTAADPDPSHGYDNRYYRIRQVQELMDTYVTHSEADVVLLGGDFNAGPNQTAGEPYAMVK--DHMQNCIEEVFYKLLEWLNPQYATYGNQKNTFSNHYTP----------IIYDYIFHHT-RDPNVVRVWTNLFELPFFKFFLKKDHEISFSDHEAVEATIYMWKK 405