Query:   10 CAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGR--YMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCP-AGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFM 526
            C  C+     +C+ C+   YCS +HQK  WK HK  C  +KI ++E LGR+L ATR +KP E++L EAP +  P  ++ PVCL C   ++      C  CGWP+C   C++   H  EC +T +RG  + +      P PLY  ++ +RCL + E S+EK      LE     R  + ++  D +++ + I +FF   + +F +E+I+   G L +N HEVP T     A++  AS  E+SC+ N +K F+ N + ++     IKK  H+SI YSD +WGT +RQ+HL++TK F C C RC D TEL+T++S+I+C      G ++      +   W+C  C++     +V  ++   G+++ S+EK + E  L ++K + + L P HF++ ++K+ L Q++ +       E+  + +  LL K     E++E+  K++P   R  G + +EL +  A   R+      +S    K+ L+E   Y+ +C+    YE     EG +   A+++   L   M
Sbjct:    4 CHVCEEPTKNKCSNCNQVSYCSVQHQKQDWKVHKPSCHPFKIAHNEQLGRHLVATRTIKPYEIVLKEAPLVRGPAQISAPVCLGCLNGIEAEDHIECEQCGWPLCGPECKSLDEHKAECGLTKDRGQKVNVQ-EFGGPHPLYTCLSTVRCLLIGETSTEKASKFQDLESLESTRRGSNQWKADLVSIGQFIPKFFK--TQKFTEEEIMKAVGALQINGHEVPTTDPSHVAVFYTASFTENSCLPNLAKSFNKNGHCILWAPREIKKNAHLSICYSDAMWGTADRQRHLMQTKLFKCACERCVDVTELDTNYSAIKCEDRQCGGLMLPTKADEWNGSWRCRECHKQVQKHYVERILERAGKDIQSMEKIA-ENGLKYLKHYEKWLPPQHFHMSEIKILLVQLLAKDQ----KELMVIPDDRLLLKLNFARELVELYEKLTPCEVRTLGTLCFELHSAIAEQTRRVALETSLSP---KDRLEESLFYVDKCVNYLKYESDIFIEGHVLKQAKINRDALRMVM 512          

Query:    9 TCAYCQIQANQRCTGCHVTFYCSREHQKLHWKK-HKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCY-------APVDGRYMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTIN---KPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEV--PVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPAGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHM--KNILQEVKKYLQECIQIFSYEPTCLQ 507
            +CA CQ +A+Q C  C    YCSREHQK HWKK H++ C  ++I  +E LGR+L ATRD+K GE IL EAP ++ P   + P+CL C+        P    + C  C WP+C + C +S  H  EC++ +      KI        +    Y V+ LLRC+++K+K  + +  L  LE H KER++   Y   +  ++  I+    +    +P+ DIL +  IL  N+ EV  P      +ALY  A+++ H CV N    FD + NI+      I KGE +SI Y+ P+  T+ R+ HL + K F C C RCQDP EL +   +  C  C AG ++SL+P    + WKC+ CN   + + V      + +EL SL+K +P A   F+ +H  +LH  + +++  K AL Q+ G +    G  + EL  + L +K +LC E+L++A+    G S  RG ++ +++      A +       S D +  +  L+   + L+E   I  +EP   Q
Sbjct:    8 SCALCQAKASQLCAACRNVVYCSREHQKEHWKKGHRSECQCFEIATNEVLGRHLRATRDIKIGEQILKEAPLVLGPKVASAPLCLGCHRNLLAPGKPRGNYHKCSSCSWPLCGKECEDSVHHKAECQLMSGSNFQSKINYVPGEEERKESAYCVIMLLRCMHLKDKDPDAFLKLYNLEDHLKERLETPLYQVLRANLITFIKTVLGMKD--WPEMDILRIAAILDTNTFEVRQPRERRKIRALYPGAAMISHDCVPNMRHRFDDDMNIVFLAKRKIAKGEILSISYTQPLRSTIQRRVHLRQAKCFDCSCARCQDPEELGSFAGAQTCLKCKAGKIISLNPLLNSAPWKCQLCNFKRSAKDVVTSDAELQQELESLDKTTPVALEEFIYRHRADLHETNTHILQAKYALTQLYGSAP---GFAMEELSGESLNRKLQLCEELLKLADIFDGGWSIFRGNLLIDMEEALVTQALR-------SKDPLDCEEKLRNAAEMLREIRNIMKHEPEMQQ 509          

Query:   49 YKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVD---GRYMCPLCGWPMCNEIC---RNSPAHI-PECRITAERGSPIKIAVTINKPFP-----LYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNG----KYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNC-NILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPAGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIA 515
            Y++ +S+  GRYL A R L+ GE ++ E P  I P     PVCL CY PV     +Y CP C WP+C   C   ++   H   EC++ AER + +   +   +  P     LYE+V ++R L +++   E++  + R+E HT+ER +N      Y    +  LRV  +   + +     E +  +CGIL VN  E+    + ++ LY +A LL H C  N +   D +   IL+R +  +++ E +++ Y+  + GT+ R+  + E K F C C RC DP EL T  S++ C  C  G + ++DP     DW C+ C        V   +  I  +L  ++        +F+ ++   L P+H+ L+  K +LCQ+ G++    G  + ++  +D+ +K+  C E LE+ + + PG++RLRG++MYEL A     A+  F +G+IS    +  L+EV K LQ    I   EP    E  +   A
Sbjct:   49 YRVEHSDIYGRYLVANRQLEAGETLIREEPLAIGPCVSGDPVCLGCYHPVSLKADQYRCPGCAWPLCGSTCAGLKHRHGHTETECQLYAERRA-VAGELLTERAGPAEVRDLYELVMIVRILLLRQHDPEQFALIARMESHTEERRQNAVLWRHYEEKVVQRLRVTWQLEDLEA-----EQVHEVCGILDVNCFEIGQNGAKARTLYPSAFLLAHDCTPNTAHTDDPSSFEILLRTSRRVREREALTLSYAYTLQGTLKRRAFMHEGKLFWCCCRRCSDPRELGTDCSALVCATCRTGSVRAVDPLQQTGDWACDRCAHKMGATEVERQLDRINNDLEDIDVHDIPGLENFLLRYRDVLRPNHYLLLSAKYSLCQIYGRTE---GYLLPQMSPEDIARKESYCREFLEIVDVLDPGLTRLRGLIMYELHAPVMVLAQSAFQSGQISRQEFQRRLKEVVKLLQVSRDILLMEPEGSTENAMGQAA 523          

Query:    6 SQFTCAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPM---------AVTPPVCLSCYAPVD-GRYMCPLCGWPMCNEICRNSPAHIPECRI-TAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFF------SVPS--TRFPDEDILALCGILFVNSH--EVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNC-NILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPG----CPAGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEA--CLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLR---GVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFM 526
            S   C  C + A+Q CT C +  YC REHQK HW +HK RC  +       LGRYL  T+++  G+++ +E P ++ P          A   P C+ CY P   G++ C  C WP+C+  C++      EC + +   GSP +        +   + + +L+CL ++ +S  K+ AL+ ++ H +ER     Y   +  ++  +++ F      + P+  T    E +  LCGI+  N    E+P  +  S  L++ A ++EH+C  N    FD     + +R    ++KG+H+ I Y++ +WGT  RQ HL  TK F+CRC RC DPTE  T+ S++ C G       G  + +DP +  + WKC+TC  +    +V  +   + E++  L  G P A      + + +  LHP+HF+  ++K  L Q+ G  +   G E+  L    L +K +LC E+  V  ++ P   +L     V++ E+       AR+  + G        ++L   +  L+E   +   E   +   KL    ++++ E E  +
Sbjct:    3 SSTECPVCGVAASQACTRCKMVRYCDREHQKQHWPQHKRRCRPFSEEQDAELGRYLKVTQNIAAGQIVFIEEPLVVGPKWYLSDADKEASNVP-CVGCYTPCRLGKHQCRRCRWPVCSAGCKHESM---ECSVLSLGSGSPTRADARSLNDYFRGDALLVLKCLLLQRQSPTKWSALLEMQSHEEERKGTDLYEEAEKRVVTYLQKRFLCRLKQTNPNLLTDCGPEMLHRLCGIIETNFMVIELPSGVELS-GLFRQACMMEHACQPNCDFQFDNKTQQVAVRAGCDLRKGDHLRITYTNILWGTQLRQHHLRLTKHFSCRCSRCLDPTEYGTYISALTCLGDVNQTCGGTHLPVDPLDENTQWKCDTCPMIVDGAYVAELQSHMTEQVEGLLAGCPSANQVELLLARLTHMLHPNHFHTFNLKHTLIQLYGNEA---GLELGVLSNTQLERKLRLCGELYNVCRRLDPYSIKLAIYVTVILIEVAHTLQEQARRAPAEG-------TSLLGLAQSRLREAHMVLEKEQESVAGKKLNEKLQMEIFECEKLI 539          

Query:   53 NSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPV-CLSCYAPVDGRYMCPLCG-WPMCNEICRNSPAHIPECRI-TAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKY--KALIRLEPHTKE-RIKNGKYSRDKMTMLRVIREFF---SVPSTRFPDEDILALCGILFVNSHEVPVTMSPS-QALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPAGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELET 524
            + E LGR+L A+  ++PG+ IL E P ++AP      + C  C    +   +C  C  +P+C +  ++      EC   T+  G  +   + +      + +  LL+ L + E    K   + LI +  +  + R   G +   +  ++R + E      +P+     + + A C  +  NS EV      + + ++   + L H CV N     D   N+ +  A+P++ G+ I   Y++P+ GT  RQ  L  ++   C C RC DPTE+ TH SS++C  CP   +  +D      DW+C  C  + T   V+ +  ++G  L+    G  +   + + ++   LHP+HF L+D+K  +  ++  ++     +  +  +K L ++ +LC+++L V   + PG+S+L  + ++E           +F+  ++S       L+       E + +  +EP    EG LA    ++L  +E+
Sbjct:   12 HDEKLGRHLVASIAIEPGDTILEERPLLVAPHWECHQLKCAQCLQ--ESYVICRRCQVFPLCMDCNQHDEF---ECEFFTSGAGKALCKDILVKN----FGICGLLKLLLLLENPRTKGDCQMLIDVPINLSDYRDGEGMWQEHEELVVRPLMESGLADVLPTQELTSDALHAHCIRIDSNSFEVTAKDGDTLKGIFVWGATLPHHCVPNTVVALDEQFNMKLYAAVPLQPGDIIYNSYTNPLMGTSQRQHQLRLSRRLECICSRCLDPTEMGTHMSSLKCKECPGFSVCEIDSNGKLGDWRCPDCRALLTAAEVHELQAAVGSALVD-AMGDLQVYEALLTQYGPLLHPNHFMLLDIKQNIASILRAAALMNSMD--QPCKKLLARRVELCSDLLPVCRAVVPGISKLYAIGLFEYLLALVELVELQFAESDLSKKEYVAHLRTASLVATEAMDLLRFEPENSAEGYLADRISMELERIES 481          

Query:   50 KICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGRYMCPLCGWPMCNEICRNSPAHIPECRITAERG-SPIKIAVTINKPFPLYEVVALLRCLYMKE--KSSEKYKALIRLEPHTKERIKN---GKYSRDKMTMLRVIREFFSVPSTRFPDEDIL-ALCGILFVNSHEV--PVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCP--GCPAGFLVSLDPFNYESDWKCETCNRVETPR--FVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSVES 531
            +I  ++ LGR+  A  +++ GE +L+E P ++ P+ +    C  C+   +    C  C      E C +      +C+  AE   S  ++ +   K     E+  +L+CL ++E  ++   Y+ + +++     R        Y     T L        +      DED++  L GIL +N++E+  P      + LY+ A L  HSC  N     D    I +     I  GE +   Y++ + GT  R++ L   K F C C RCQDPTEL TH SS  C    C  G++V          W+C   N   T +  FV+ ++    EE+    +         + K S+ LH +HF ++D+K  +  ++ Q     G+     ++K   +K +LC EIL V   ++PG+SRL+ + +YEL    A  ARK ++  E S++ +   L+ V+  L+E +++  +EP    EG+L    R  L EL+   D +++
Sbjct:   13 EIKQNDTLGRFAVALCNVRAGETLLLENPIVVLPL-MGERRCSKCFNLTES--FCRKCRLLALCEDCSDHDER--DCKRLAEMNFSDDQVELLQKKEHT--EIQPVLKCLLLREHEETLPLYEEMSQMDSQLMTRRGTEVWKNYQEHAFTPLDYGGVLAQLRGA--ADEDLVQGLLGILDINAYEIRAPEVGGAMRGLYRRAGLFAHSCTPNLVISIDDEQRIKVYANRFIAAGEILYNCYTNVLLGTEERRKILKVGKCFDCSCPRCQDPTELGTHMSSFICSQCSCVDGYIVRQPDTGI---WQC-LLNPEHTLKQEFVSNMLERAKEEIFH-ARDDIYRQELLLAKLSRLLHRNHFLMLDLKQNIASILRQILQNMGTRP---NKKVYERKIRLCQEILLVLKVVTPGISRLKAIALYELANTQAELARKMYTEMEHSANDLLAELERVEVMLRESLRMLLFEPLATPEGQL---TRSMLRELKELQDDIKN 487          

Query:   48 SYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPV--CLSCYA--PVDGRYMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPL-YEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPST-RFPDEDILALCGILFVNSHEVPVTMSPSQALYQN----ASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRC--PGCPAGFLVSLDPFNYESDWKCETCNRV----ETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFY-LMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQ 460
            ++ I +S   GR + ATRD+  GELI  E   +  P A    +  C+ C+   P  G      C  P+C E C +S  H  EC     R  P  +     +  P+   ++  +R  ++     ++ + L+       ER     Y R+ +   +  R F   P+T R   + +  + G+L  N+ E P      + L +      +++ H C  NAS +F+     ++R A  I KG  I+  Y+  +WG + R   L  TK F C C+RC D TE  T+ S++ C   GC  G ++ +     + DW+C TC  V    +  ++ +  + +I   + S    S +  + F+ +      P   Y L++ KL +   + +  +       E   +++    +   E+L + +K+  G   L+ ++  E+Q
Sbjct:   56 NWTISSSTVAGRGVFATRDIAAGELIFQERALVTGPTARKGQLSSCICCHETLPQTGFLCRHRCTLPVC-ETCSDSEEHQAECE-HFRRWQPKDVDAEQEQVNPMSLRILTAVRVFHL----GKEQRHLVDAMQANAER----AYRREIIQAAQCFRNF---PTTDRVFMDQLFRIVGVLNTNAFEAPCRSGGHETLLRGLFPLTAIMNHECTPNASHYFENGRLAVVRAARDIPKGGEITTTYTKILWGNLTRNIFLKMTKHFACDCVRCHDNTENGTYLSALFCREQGC-RGLVIPVQTRTLQPDWRCITCENVFPHAKMAKYQDFALNTINNRINSC---SVQDMIHFINELCPRFCPSSNYVLIEAKLNVIWRMTRFDHE------EYTPEEMGHMDRYREEVLAILHKLGAGECTLKKLITGEIQ 462          

Query:   37 LHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPV----DGRYMCPL-CGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALI-----RLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPS------QALYQNASLLEHSCVNNASKHFDMNCN-ILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCP-AGFLVSLDPFNYESDWKCETCNRVET-PRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFY-LMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLR 452
            LH    K++  +++I  S+  GR + ATR LK GE+I  ++P +I   A       +C   +    D R+MC   CG P+C+ +C     H  +C +    G         N+P     VV  L C+      S++ + LI      L+ + +  ++N              + F + P+ +   E +     +L  N  +     +        +ALY    ++ H C+ NA   F+   N +++R A+ I +G  ++  Y+    G + R   L   K FTC+C RC DPTE     S + C     AG +V         +W C  C +  T  + + +   + G     +   S    + ++ + S +  P   Y ++D K+++ Q + Q       E+   H   L    +   +I ++ +K+  G S LR
Sbjct:   13 LHLAPFKDKDPAWEIGVSKIAGRGVVATRSLKRGEIIFRDSPLLIGLAAHEEDSLNACSVCLKMLPDTRFMCRQGCGLPVCS-LCAKKKQHKSDCDLFKSWGP--------NEPDVANSVVIRLLCVARAINLSKEQRDLIYCLQANLDNNHRTEVRNA------------AKCFKNFPTDKKLIEIMNRTVAVLRTNGFDKTTDRTNDNQEFNYRALYPLFGVVNHDCIPNAYYTFEEKTNNMIVRAAVDIPEGFEVTTTYTKLFTGNIARHLFLKMKKSFTCKCSRCSDPTEKGAFISGLYCRDTNCAGLVVPEITGLPHPNWNCLVCKQKSTHAQMMKSQDFASGAINAKVNSNSLRTLVQYLNEKSDSFIPSSNYVVIDAKMSVLQRLQQGREDCSEEL--AHNTRL----RYSRDITQLMDKLGLGDSLLR 421          

Query:  153 ALLRCLYMKEKSSEKYKA-----LIRLEPHTKERIKNGKYSRDKMTML-RVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRC---QDP 311
            ALLR +   E     Y          LE H  + +       +++ +  R ++E+     T   +E I+A    L +NS  +         L+  A+L+ HSC  NA   FD    I ++   PI  GE I I Y D  + T  RQ+ L E  FFTC C +C   +DP
Sbjct:  124 ALLRMVLRTEARKNAYTEEELVLFQTLETHIDDILNRNAPQAERIALTSRAVKEY---SKTDMEEEKIVAYHARLDLNSFNLTNDDDIGIYLHPYAALINHSCDYNAVVGFD-GSEIFVKAIRPIATGEQIFISYIDTTYPTRIRQKELQERYFFTCNCAKCLCAKDP 287          

Query:  153 ALLRCLYMKEKSSEKYKA-----LIRLEPHTKERIKNGKYSRDKMTML-RVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRC---QDP 311
            ALLR +   E     Y          LE H  + +       +++ +  R ++E+     T   +E I+A    L +NS  +         L+  A+L+ HSC  NA   FD    I ++   PI  GE I I Y D  + T  RQ+ L E  FFTC C +C   +DP
Sbjct:  124 ALLRMVLRTEARKNAYTEEELVLFQTLETHIDDILNRNAPQAERIALTSRAVKEY---SKTDMEEEKIVAYHARLDLNSFNLTNDDDIGIYLHPYAALINHSCDYNAVVGFD-GSEIFVKAIRPIATGEQIFISYIDTTYPTRIRQKELQERYFFTCNCAKCLCAKDP 287          

Query:    7 QFTCAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGRYMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVT-INKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPA---GFLVSLDPF---NYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSVESK 532
            QF CA C   ANQRCTGCH+TFYCSR+HQK HWKKHK+ CC+YK+C+S  LGRYL ATRDLKPGE+++ E P +I P +VT P+CL+CY P + +Y C  CGWPMCN  C  SP H  EC +TA RG+P+++     NKP+P+YEVVA+LRCLY+K+ S  K+K L  LEPH + R KN +Y +D  TM+RVI+EF  +P T F  ++IL +CG+L VN+H++PVT +P  ALY N S+LEHSC+NNASKHFD +  ++IR A+ IKKGEHISI YSDP+WGT +RQ HL ETK+F C+C+RC DPTEL T FSSI+CP C A   G+LVS +P      ++DWKC  C ++++  FVNAV +SIGEEL+ LEKGS EAC SF++KHSQNLHP+H+YL D+KLALCQMIGQS+ G G EIF L EK+LL KQK+  E+LEVANKISPG+SRLRGV++YELQA  AAYAR+KFS+GEISSDHM+N+++EVKKYL ECIQIFS+EP CLQEG+LA IARLDL+ELETF+DS+E K
Sbjct:   83 QFVCAQCGGAANQRCTGCHITFYCSRDHQKQHWKKHKSSCCAYKVCSSPELGRYLVATRDLKPGEMVISETPLVIGPQSVTIPICLACYKPANSKYACGKCGWPMCNANCAKSPVHEAECTLTAARGAPLQLPPNCYNKPYPIYEVVAILRCLYLKQTSEAKWKKLKELEPHEEARKKNKRYEKDIDTMVRVIQEFLKIPETVFTTQEILDVCGVLNVNAHDLPVTPTPVMALYANISILEHSCINNASKHFDGDYRVVIRAAVNIKKGEHISINYSDPMWGTSSRQLHLNETKYFICKCVRCADPTELGTMFSSIQCPQCTAEQGGYLVSTNPGLGPESQADWKCIVCQKIQSHTFVNAVTQSIGEELVRLEKGSVEACQSFIRKHSQNLHPNHYYLQDIKLALCQMIGQSATGQGHEIFNLTEKELLYKQKIGMELLEVANKISPGISRLRGVILYELQATLAAYARRKFSSGEISSDHMRNVMKEVKKYLLECIQIFSFEPPCLQEGRLATIARLDLLELETFLDSLEQK 1681          

Query:    9 TCAYCQIQANQRCTGC---HVTFYCSREHQKLHWKKHKNRC--CSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGRYMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSV-------PSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPAGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISL-EKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRL---RGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIF-SYEPTCLQEGKLAAIARLDLVELETFMDSV 529
            TC  C   A  +CTGC      +YC+R  QK  WK HK+ C   +YKI +S  LG +L A R +K GE+IL E P +  P  +T PVCL+CY PVDG Y+C   GWP+C   C    A  PE  + A+  +  +I     +P  LYE + ++R L +++ +  KYKA + LE H +ER     +++ K T++ V+++   +       P   F DE I  + GIL  N  E+ ++ S  +A+Y  A L+EHSC  N    FD + +I +R    I  GEHIS MY+  +WGT+ R+ HL  TK F C C RC DP E  ++FS+I   G P   ++ LDP + ESDW CE      T + +   +  IG EL  +  KG+ +   +F++K+ + LHP+H+++   K  L QM G++       I ++ E+ L +K++LC E + V   I P   RL        +EL       A++K+ +G IS++  +  L+E   +++  + +  + E   L EG+L   A   L +LE FM +V
Sbjct:   68 TCPVCGKIATTKCTGCTGDDQVYYCNRNCQKKDWKLHKSVCKKLAYKIGSSPELGNHLVANRAIKAGEVILREVPLVHGPSQMTIPVCLACYTPVDGSYLCQRSGWPLCGPTCAKLVAKSPEVIVPAQCDAKFEIEEYF-QPSYLYECIIVMRTLLLQKSAPAKYKAFMSLESHNEERRGTPAWNKVKETIIDVMKKTLGIMVFEAVCPEIDFSDETIQKIQGILETNKKEIRLSASDCEAVYAIACLMEHSCTPNVKITFDKDFSITVRAGRDITVGEHISTMYTHALWGTIARRDHLHITKNFWCTCPRCIDPFEFGSNFSTIFDDGHP---MLPLDPLDSESDWVCEKTGMKRTAQEIKLQLSQIGAELEEVTAKGTVDDAEAFLEKYKKLLHPNHYHMTTCKHNLLQMYGRTETCL---IQDMDEEQLKRKEELCREHISVLEFIDPSKIRLMIFAAAANFELHLPLLQVAKRKWESGNISTEEFREALKEPYNHVKIAVDLLVNEENENLPEGQLRLQATDTLTQLEGFMKTV 1660          

Query:    9 TCAYCQIQANQRCTGC---HVTFYCSREHQKLHWKKHKNRC--CSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGRYMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSV-------PSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPAGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISL-EKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRL---RGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIF-SYEPTCLQEGKLAAIARLDLVELETFMDSV 529
            TC  C   A  +CTGC      +YC+R  QK  WK HK+ C   +YKI +S  LG +L A R +K GE+IL E P +  P  +T PVCL+CY PVDG Y+C   GWP+C   C    A  PE  + A+  +  +I     +P  LYE + ++R L +++ +  KYKA + LE H +ER     +++ K T++ V+++   +       P   F DE I  + GIL  N  E+ ++ S  +A+Y  A L+EHSC  N    FD + +I +R    I  GEHIS MY+  +WGT+ R+ HL  TK F C C RC DP E  ++FS+I   G P   ++ LDP + ESDW CE      T + +   +  IG EL  +  KG+ +   +F++K+ + LHP+H+++   K  L QM G++       I ++ E+ L +K++LC E + V   I P   RL        +EL       A++K+ +G IS++  +  L+E   +++  + +  + E   L EG+L   A   L +LE FM +V
Sbjct:   68 TCPVCGKIATTKCTGCTGDDQVYYCNRNCQKKDWKLHKSVCKKLAYKIGSSPELGNHLVANRAIKAGEVILREVPLVHGPSQMTIPVCLACYTPVDGSYLCQRSGWPLCGPTCAKLVAKSPEVIVPAQCDAKFEIEEYF-QPSYLYECIIVMRTLLLQKSAPAKYKAFMSLESHNEERRGTPAWNKVKETIIDVMKKTLGIMVFEAVCPEIDFSDETIQKIQGILETNKKEIRLSASDCEAVYAIACLMEHSCTPNVKITFDKDFSITVRAGRDITVGEHISTMYTHALWGTIARRDHLHITKNFWCTCPRCIDPFEFGSNFSTIFDDGHP---MLPLDPLDSESDWVCEKTGMKRTAQEIKLQLSQIGAELEEVTAKGTVDDAEAFLEKYKKLLHPNHYHMTTCKHNLLQMYGRTETCL---IQDMDEEQLKRKEELCREHISVLEFIDPSKIRLMIFAAAANFELHLPLLQVAKRKWESGNISTEEFREALKEPYNHVKIAVDLLVNEENENLPEGQLRLQATDTLTQLEGFMKTV 1660          

Query:   10 CAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCS-----YKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGR---YMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSR-DKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPA----------GFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTC--LQEGKLAAIARL 517
            CA C   A   CTGC   FYC+R+HQ+ HW  HK+ C S     Y++  S+ +GR+L AT+DL+ GELIL E+P ++ P  +T PVCL C+  +        C  C WP+C+E C++SP H  ECR T   GS IK+    ++   +Y  +A+LR L +++   + ++   + + H +ERIK   Y++ +K  ++  I ++ ++   R+ D +IL  CG L  N  E+       +A+Y+ A ++ H C  N    FD +  I I     IKKGE I   Y++ +W T++R+ HL  +K F C C RC DP+E +++ SSIRC  C             FL+  DP N ES+W+C+ C  ++    + A   ++  EL  L++       +F+ K+   L P++ +++++K A+  M+G         +  L +++L  K++L  +++E+A+KI PG S+ +G ++ ELQ    + A      G I+    K       + L+   +I   EP    + + ++ AI+ +
Sbjct: 2535 CAVCGKIAKAICTGCKHVFYCTRDHQRKHWSSHKDECKSMAKLPYRVERSDIMGRFLIATKDLEEGELILNESPMVVGPRQLTKPVCLGCHKEITSTTPFIKCVRCNWPVCSERCQDSPMHDSECRATKAAGSRIKVE-HFDQINMMYACIAILRALALQDGPRKIWEDYTKFDSHLQERIKTPVYNKVNKEKVVFFIHQYLNI--QRYSDLEILEACGKLDTNCFEIKQNGLNLRAMYRTACIMSHDCRPNTRHTFDPDNAINIYSTQQIKKGEVICATYTNSLWSTIDRRDHLQMSKCFLCTCNRCSDPSEYDSYLSSIRCSRCAGFSDHIQNKDLQFLLPEDPLNAESNWRCQKCTNIQKASQIKAGNMTVSNELKELDRSKISNMTNFLTKYENMLGPNNHHVVEIKFAIVMMLGNRRPYL---LENLTQEELELKERLSAQLIELADKIEPGSSKWKGQLLLELQMAQISLAAGLEETGAITRFAAKEKAAIAMENLKNSARILQVEPDMRPILQDRMTAISAM 4103          

Query:   10 CAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCS-----YKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGR---YMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSR-DKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPA----------GFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTC--LQEGKLAAIARL 517
            CA C   A   CTGC   FYC+R+HQ+ HW  HK+ C S     Y++  S+ +GR+L AT+DL+ GELIL E+P ++ P  +T PVCL C+  +        C  C WP+C+E C++SP H  ECR T   GS IK+    ++   +Y  +A+LR L +++   + ++   + + H +ERIK   Y++ +K  ++  I ++ ++   R+ D +IL  CG L  N  E+       +A+Y+ A ++ H C  N    FD +  I I     IKKGE I   Y++ +W T++R+ HL  +K F C C RC DP+E +++ SSIRC  C             FL+  DP N ES+W+C+ C  ++    + A   ++  EL  L++       +F+ K+   L P++ +++++K A+  M+G         +  L +++L  K++L  +++E+A+KI PG S+ +G ++ ELQ    + A      G I+    K       + L+   +I   EP    + + ++ AI+ +
Sbjct: 2535 CAVCGKIAKAICTGCKHVFYCTRDHQRKHWSSHKDECKSMAKLPYRVERSDIMGRFLIATKDLEEGELILNESPMVVGPRQLTKPVCLGCHKEITSTTPFIKCVRCNWPVCSERCQDSPMHDSECRATKAAGSRIKVE-HFDQINMMYACIAILRALALQDGPRKIWEDYTKFDSHLQERIKTPVYNKVNKEKVVFFIHQYLNI--QRYSDLEILEACGKLDTNCFEIKQNGLNLRAMYRTACIMSHDCRPNTRHTFDPDNAINIYSTQQIKKGEVICATYTNSLWSTIDRRDHLQMSKCFLCTCNRCSDPSEYDSYLSSIRCSRCAGFSDHIQNKDLQFLLPEDPLNAESNWRCQKCTNIQKASQIKAGNMTVSNELKELDRSKISNMTNFLTKYENMLGPNNHHVVEIKFAIVMMLGNRRPYL---LENLTQEELELKERLSAQLIELADKIEPGSSKWKGQLLLELQMAQISLAAGLEETGAITRFAAKEKAAIAMENLKNSARILQVEPDMRPILQDRMTAISAM 4103          

Query:   49 YKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVD---------------------GRYMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPV--TMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPAGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKG--SPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYEL-----QAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSVESK 532
            Y+I  S  +GR++ AT+ L+ GE++  + P +  P   + P C++CY P+D                        +CP C WP+C+  C +S  H PEC    + G  I  A + +    LY+V+ +LRCL++KE +   +  L+ L+    + +      R K     +   F       F  E +  +C  L +NS E+P+  T +  Q ++  A ++EH+C+    + F+ + +I +R A   ++G+ +SI Y+D +W T  R+++L+ +K F C C RCQD TE  T  S+IRC  CP G+ ++ +P + E  W C  C     P +       +   +  +E+   +PE+C  F+K +S+ LH +H +++DVK +L  ++G S    G  + +L E  LL K+ L    LE+A+KI PG+SRL+G  ++EL     Q    A    K +   +S   +  ILQ    +L ECI+   YEP+   EG L + AR + +++   M+SV++ 
Sbjct:  336 YRIGQSPEVGRHIVATKKLEKGEVVFKDVPIVTGPSRESDPCCVACYKPIDLASPKVNSQSDCEMEVDSGPVPHVLCPRCKWPVCSIECADSETHKPECFYLTKSGCNINPADSDS----LYDVITVLRCLFLKENNLRAWANLLTLQEANPKELNPELADRAKKVTGLICGTFKL--GEEFCKELVFDICTRLDINSFEIPLGRTSATVQGIFTVACMVEHNCIPTGHRCFNSDMSITVRSAYGAEEGDAVSICYTDSLWPTAARRENLIYSKDFLCTCDRCQDETENETFMSAIRCIKCP-GYFLAENPLDCEGKWICNECGTTAPPGYSEMAYSKVASAIAKIEEEGLTPESCEKFIKNYSKVLHANHAHMLDVKFSLLNLLGHSE---GYTMSQLSEAQLLLKESLARTFLEIASKILPGISRLKGTALFELYLCMQQRGIRAVNEPKMN---LSPPEVLGILQNAYDHLMECIECLQYEPSHQPEGHLCSRAREEQMQMILLMNSVKAN 1838          

Query:    8 FTCAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXL-GRYLXATRDLKPGELILMEAPTIIAPMAVTP-PVCLSCYAPVDGRYMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTML--RVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRC--PGCPAGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSVESK 532
             +C  C       C GC    YC ++ Q+ HWK+HK  C  Y I +SE   GR++ +TRD+KPGE ++   P  + P    P P CL C++       C  CG  +C+  C   PAH  EC++ AE G+   + + I  P         LR + ++E +  +Y+ ++ +E + +E       SR     L   VI    S+       E I  + GI+  NS EV         L+   +++ H CV N     D +  + +  +  IKK   +   Y   +  T  RQ +L+E KFFTC C RC DP+EL +H SS++C    C    L S DP + + DWKC +C        V  +++ + +E   L   + +  +  + K SQ LHP+H  L ++K  L   +G+     G  I E+ E D LQK  LC ++LEV + + PG+S  RG++++EL +     +  +F   + +S  +  +L E + YL+E  +I + EP     G+LA+  +  + +L  ++ SV+++
Sbjct:  102 MSCTVCSETTATPCGGCGTVSYCGKDCQRKHWKQHKANCKPYTIVSSEEEHGRHMRSTRDIKPGETLMSTLPACVGPRLHQPTPCCLGCHSAKAKLIKCTKCGLSVCSSSCAKKPAHQGECQLIAESGTEDILGIGIVTP---------LRIIALRESAPNEYETILSMEGNLEEL-----KSRPIWNYLEENVITPVLSLNIKNISIEIIEQIVGIILTNSFEVVGAGCLLFGLFFPPAMMNHHCVGNVRITLDDSNRMTVYASRQIKKNTPVKFNYGRALDTTWTRQINLMENKFFTCACERCLDPSELGSHISSLKCYQSDCIGPVLPS-DPLSMKQDWKCSSCKTGVKAEDVRNILKELQKETAVLNSNNLKEVMQVLNKFSQLLHPNHGVLTELKQFLISGLGRLP---GYAIVEMKESDHLQKISLCRQVLEVLDIVDPGLSLGRGLMLFELHSTLVMVSNMEFEKTQNASIMLSRLL-EAETYLKEASKILTVEPPNSPYGQLASTVKHSMADLTEYIHSVQNQ 1637          

Query:    8 FTCAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXL-GRYLXATRDLKPGELILMEAPTIIAPMAVTP-PVCLSCYAPVDGRYMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTML--RVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRC--PGCPAGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSVES 531
             +C  C       C GC    YC ++ Q+ HWK+HK  C  Y I +SE   GR++ +TRD+KPGE ++   P  + P    P P CL C++       C  CG  +C+  C   PAH  EC++ AE G+   + + I  P         LR + ++E +  +Y+ ++ +E + +E       SR     L   VI    S+       E I  + GI+  NS EV         L+   +++ H CV N     D +  + +  +  IKK   +   Y   +  T  RQ +L+E KFFTC C RC DP+EL +H SS++C    C    L S DP + + DWKC +C        V  +++ + +E   L   + +  +  + K SQ LHP+H  L ++K  L   +G+     G  I E+ E D LQK  LC ++LEV + + PG+S  RG++++EL +     +  +F   + +S  +  +L E + YL+E  +I + EP     G+LA+  +  + +L  ++ SV++
Sbjct:   84 MSCTVCSETTATPCGGCGTVSYCGKDCQRKHWKQHKANCKPYTIVSSEEEHGRHMRSTRDIKPGETLMSTLPACVGPRLHQPTPCCLGCHSAKAKLIKCTKCGLSVCSSSCAKKPAHQGECQLIAESGTEDILGIGIVTP---------LRIIALRESAPNEYETILSMEGNLEEL-----KSRPIWNYLEENVITPVLSLNIKNISIEIIEQIVGIILTNSFEVVGAGCLLFGLFFPPAMMNHHCVGNVRITLDDSNRMTVYASRQIKKNTPVKFNYGRALDTTWTRQINLMENKFFTCACERCLDPSELGSHISSLKCYQSDCIGPVLPS-DPLSMKQDWKCSSCKTGVKAEDVRNILKELQKETAVLNSNNLKEVMQVLNKFSQLLHPNHGVLTELKQFLISGLGRLP---GYAIVEMKESDHLQKISLCRQVLEVLDIVDPGLSLGRGLMLFELHSTLVMVSNMEFEKTQNASIMLSRLL-EAETYLKEASKILTVEPPNSPYGQLASTVKHSMADLTEYIHSVQN 1616          

Query:    6 SQFTCAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVD-GRYMCPLCGWPMCNEICRNSPAHIPECRITAE---------RGSPIKIAVTINKPFPLYEVVALLR-CLYMKEKSSEKYKALIRLEPHTKER--IKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRC--PGCPAGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLV 520
            S+ + A C + A   C GC  T YCS+EHQK  W  H+  C  +KI      GR+L ATRD+KPGE+IL E P    P   T PVCL C+  V    Y C  C WPMC+E C   P H  EC + A+         R + +++   +    P+YE V  LR CL M  K  E +K + ++E H +ER  +++  +++  +    +     +       +E +      L VN+ E+  +    + LY   +++  SC  N     D +    +R A  I+KGE I   Y+  +  T+ R++ L  +K+F CRC RC DPTEL +HFS++ C   GC AG++V  DP NY ++WKC  C      R V A      E++ +  K + E+    ++  S   HP+H   +DV+  L  ++G S     +++    EK L         I+EV NK+ PG+ R+RG+ + EL        R K  + EIS       L   +  L E   I  +EP    +G + A +RL+ V
Sbjct:  147 SECSAAECSLTAPLTCGGCQKTSYCSKEHQKKDWANHRKLCSPFKIVQKPGYGRHLVATRDIKPGEVILEEVPVTCGPKQYTAPVCLGCHKLVSLSGYRCSGCEWPMCDEKCAKRPIHQGECSVFAQSKLKPTSLKRKNGMEMEPDMEIEHPIYECVTSLRVCLVMGLK-PENWKVVEKMETHREERQLMEHSLHNQHNIVTFLLKHAKLAEIIPGVTEEHVTRAIDALDVNAFEIRGSFHSIRGLYPLTAMMNASCSPNTQNSIDADWVCRVRAARKIQKGEEICDTYTATLSNTLYRRKSLKNSKYFDCRCSRCADPTELGSHFSTLLCRVQGC-AGYVVCKDPLNYAANWKCLKCETEMPGRDVQAEQEEWEEKIENAPK-NIESQKKLLEALSLLYHPNHNMCVDVQFNLVPLLGLSK---KTDLIAEAEKKL----GFVENIIEVMNKVIPGMFRMRGMFLAELYTTKLFLLRSKLESKEISKSVFVRRLAGFRTILVEAKTILEFEP----QGSIEA-SRLESV 1691          

Query:    8 FTCAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNS-EXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVC-LSCYAPVDGRYMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRC--PGCPAGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSVES 531
             +C  C       C GC    YC +E QK HWK+HK +C +YKI  S E  GR + A RD+K GE +++  P  + P    P +C L C+   D    C  CG P+C+  C  S  H  EC +     S  K  VT  K   +  VV  LR + +K    E Y   + +EP+  E +K  +  +   T   VI+    +       + +    GI+  N  EV         +Y   +L+ H CV N+    D +  + +    PIKKG+     Y   +  T  RQ +LLE K+FTC+C RC DPTEL ++ SS++C    C  G  +  DP + + DW C  C  V     V  +++S+ ++  +L++   +A     KK++  LH +H  L ++K  L   +G+     G E+ +L E D  QK  LC E+L+V + + PG+   RG++M+EL +     +  +F   +     +  +L E  K+L+E  +I   EP     G LAA  + ++VEL  +++SV++
Sbjct:   74 MSCKVCNATPATPCGGCSAVSYCGKECQKTHWKEHKAKCKAYKIVTSAEEHGRNIVAARDIKAGETLMVTRPFCVGPRMHKPALCCLGCHRAADKLMSCDKCGLPVCSVKCAGSNTHQMECTLITN--SKDKNNVTDLKLGIM--VVTPLRIIGLKFTKPELYATAMSMEPNL-EVLKERELWKYLDT--HVIQPVLGLQIEGITLDIVERCVGIILTNCFEVMAKGCLLFGMYFEPALMNHHCVGNSRLMLDSSNLMTVIACQPIKKGKPAKWNYGRALDTTWTRQVNLLENKYFTCQCERCLDPTELGSNISSLKCREDKC-EGSTIPKDPMSMKGDWICVKCGDVVNGECVRKLLKSLQKDTENLDRNDMKAVKDIFKKYAGKLHKNHGVLTELKQYLISGMGRLP---GYEMDDLKESDHKQKVLLCQEVLDVLDIVEPGMMLGRGLMMFELHSSLVMVSNMEFEKKQNPGQLLCRLL-EADKFLREAEKILKMEPRNSPYGHLAATVQSNMVELSAYIESVKN 1621          

Query:    1 MAEAESQFTCAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGRYMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPAGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSVESKKAIQ 536
            MAEAESQFTCAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGRYMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPAGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSVESKKAIQ
Sbjct:    1 MAEAESQFTCAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGRYMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPAGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSVESKKAIQ 536          

Query:    3 EAESQFTCAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCS-----YKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGR---YMCPLCGWPMCNEICRNSPAHI-PECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSR-DKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPAGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEP 503
            E  +Q  C  C   A   C+ C   FYC REHQK HW  H   C       Y+I  +  LGRYL A  D+  G LI  E P +I P  +T  VCL C+  +  +   Y C  C WPMC+  C +SP H   EC I +  G  + I         +Y  + +LR L +K  +  K++  ++ + H  ER+    Y + +K  ++  I  F  + S +F D +IL  CG L  N  E+       + LY+  S++ H C  N    F+ N +I +   + IKKGE I   Y+ P+W T++R++HL  +K F CRC RC DPTE  T+ S+  C  C  G ++ LDP + +S+WKCE C+       V   I S+ +EL S+++ +PE    F+K+++  L   +    +++L L  +             +L    LL+K  +C ++L VAN++ PG S+ RG ++ E+Q+      ++  + G IS+   K+I  E  K+L+E  ++   EP
Sbjct:  130 ENTAQGDCIVCGELAKNFCSSCKYVFYCKREHQKSHWSSHSKECAHFKALPYRIERNPRLGRYLVAKDDISEGSLIFNEPPLVIGPRQLTKAVCLXCHNELKDKKDTYPCRRCTWPMCSRSCSDSPVHANAECSILSYGGVKVNIDA-FGTANMMYACITVLRALSLK--NDHKWQEYLKFDSHLNERMPTQVYQQVNKEKVVFFIHYFLKLLS-KFSDLEILEACGKLDTNCFEIRQFGKNLRGLYRIGSIMSHECTPNTRHTFEENYDINVYSTVDIKKGEIICATYTQPLWCTLSRREHLNMSKCFWCRCKRCSDPTEFGTYLSAFSCSEC-GGKMLPLDPLDQKSNWKCEKCSHTLESTTVRHGIESMMDELKSIDRTNPENLEDFLKRYATLLPETNQLTREIQLGLVSLFKNRRNE------DLKTTQLLRKAFMCRQLLTVANRVDPGFSKWRGELLLEMQSANVILGQRALAEGRISNIQAKDIFDENMKHLKEADRVLCIEP 629          

Query:    8 FTCAYCQIQANQRCTGCHVTFYCSREHQKLHW-KKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGRYMCPLCGWPMCNEI-CRNSPAHI-PECRITAERGSPIKIAVTINKP---FPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMN--CNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGC-PA------GFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKH-SQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKY---LQECIQIFSYEPTCLQEGK 510
              C  C    +Q C+GCH   YCS+EHQK HW + HKN CC+YK+   E  GR L  TRD++PGE+I  E+P  + P     PVCL CY  V+G  +C  C WPMC  I C  +P H   EC + A+    +K  + +NKP    P+Y+ +  LRCL +KE   + +  L  +E HT+ R     Y  +++ +++ I E     +T    EDI     ++ VN+ E+         LY   +++  +C  N     D N  C ++    IP  KG  I+  Y+  + GT+ R+  L E+K+F C+C RC DPTELN+HFS++ C    P+      GF+ S +  N  + W C  C  V +   V  + + +  E I  E  + +   +F+K    + LHP+H+ ++D K  L + + ++ Y       E+  +  ++K+++  +IL+V + I+PG  R+R +++ E      + A    SN    S+  +  L+E ++    L+EC+ I  +E T   EG+
Sbjct:   27 LNCPECGKCVSQFCSGCHSVGYCSKEHQKNHWLQGHKNECCAYKLVKKEGHGRILIVTRDIEPGEVIFEESPITVGPKQFCQPVCLGCYKNVNGTSICSGCNWPMCGNIECEKAPIHSKKECALLAD--CHLKPIIDLNKPEKDLPIYQFLTALRCLLVKEFRPDNWSILESMESHTELRKNEESYRVNQVNIVKFILERIKYDTTV---EDINKCIDVMDVNAFEIRSHEFSIAGLYPMTAMMNSNCSPNTQNSIDENYICRVMAITRIP--KGSEINSTYTRTLSGTLYRRNQLKESKYFDCKCERCCDPTELNSHFSTLLCQAILPSISKTCKGFVYSENSLNTNASWICRACGAVMSHEEVTELTQKLEVE-IEKEFLTIDDYENFLKNRLLKFLHPNHYIIVDFKFILMKALSRAEYDP-----EIRIQREIRKKRIIEDILDVHSLITPGYFRIRAMLVSERCMVMMSIAFHNLSN----SNKNEIFLEECERIIDGLEECVSILRFENTNSVEGQ 531          

Query:    2 AEAESQFTCAYCQIQANQR-----CTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGRYMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIK-NGKYSRDKMTMLRVIREFFSV---------PSTRFPDEDILALCGILFVNSHEV----PVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPAGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIAR 516
             E ++   C +C  +  +      C  C + +YCS EH  +H  +H NRC  + +  S+  GRY+ A RD+ P ELIL E P ++ P +   P CL+C+  VDG Y C  CG P+C++ C     H PEC    +    IK        +     V  LR L MK+     ++ +  L  H +ER+  N + +   + ++  ++E  S           S  F  ++I  + GIL  N  +     P    P  ALY    L+ H+C NN +     + ++ +R  IPIKKGE I   Y     G + R+Q + +  FF C C RC D TEL T+ S I C  C  G+L+ ++  NYESDW C  C+ +   + ++ +I +I  ++ S+E  + +     +  + + LHP+H+ ++D+   L  +          E     EK+  +K +LC  +LE   ++ PG ++ RG ++ E+       +++      I+       L    + L E  +  +   T L E  +++I +
Sbjct:   60 VEVDNDMCCFFCGNEEEEDNHLTLCPFCKIVYYCSEEHYIIH--RHSNRCFPFIVKRSKRFGRYMVAARDINPLELILSEQPAVVGPYSKKLPGCLNCFRLVDGSYYCSKCGVPVCDKECEIGDLHRPECGYFQKNNFVIKKE----NHYSSQACVTPLRMLLMKKSDPNTFRKIDMLMDHIEERVVINKQVNIQLLNIILFLKEVSSSKEFNQNEVSTSNDFDQKEIQRMLGILKTNGMKFEPLGPERGCPGVALYPVYCLINHACFNNTNYVKFPDFHLELRSQIPIKKGEQIFTRYVSSTIGNLRRRQDIKQYWFFDCECQRCIDRTELGTYMSGINCKHCKNGYLLPINSLNYESDWSCNNCDVIVNYKTISDIIDTIESQVRSIEHETIDELEEMLYHYQKLLHPNHYIVIDIMHNLIHVYA------AKETLTRPEKE--RKIQLCMSVLETLGRVDPGYTKWRGTILQEMIYPLMMVSKEDHEYKRITEREFHKRLNICARKLAEAKKCLTGGFTKLTENSVSSILK 579          

Query:   36 KLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPV--DGRYMCPLCGWPMCNEICRNSPAHIP-ECRITAERGSPIKIAVTI---NKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPS-------QALYQNASLLEHSCVNNASKHF---DMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPAGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKG-SPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQ---AXXAAYARKKFSNGEISSDHMKNI 484
            KL+ ++ ++    YKI  ++ +GRY+ ATRD+KPGE +LME P    P     P+CL CY PV  +    C  CG+PMC++ C     H   EC         +    T+        +Y  ++L+R L +K++   ++  +     H + R K+  + +     L  I+    +    +  + I  + GI  VN  E+ + +  S       + ++  AS+  HSCV+N   +F   +    + ++  + IK+G+ I+  Y++P+   + RQ  L   KFF C CIRC+DPTE++T+ S++ C  C  G ++S +  N  SDW+C++C+   +P  V  V      E+  ++K    E    F+ K++   HP+H Y++D    L +M G+     G E   L +   ++K++LC  +L+V N I+PG +R +G++MYEL          A +K  NG +    +K I
Sbjct:   18 KLYIERDQSSNRPYKIIRNDSVGRYMVATRDIKPGETVLMEYPLTFGPGNPNEPICLGCYTPVLKNQHTECDGCGFPMCSKECSQILEHKDFECAEMHNMNFRLDSQNTLKWNGSQESVYNAISLMRALVLKKRDPARWNLIWMHMSHDEARQKDTFWQKKDAKTLEHIKAMMKISPEDY--DTIKIILGIFLVNDFEICIPLEGSDEKSSLIRGIFALASMPNHSCVSNCYHNFTCREEGFKMTMKAVVDIKEGDEITHSYTEPLDPIMRRQSLLKIGKFFQCNCIRCRDPTEMSTYSSALICSKCKKGNVISKNCKNINSDWECDSCDLTLSPDSVEQVNSKAKSEIEEMDKNPDVETHEQFLNKYATIFHPNHVYMIDRSYVLGKMYGRME---GYEPDSLSDDQFMRKKELCERVLKVLNVITPGQTRKKGMMMYELHLPFVIMGNRALQKGPNGNVDPQEIKKI 481          

Query:    1 MAEAESQFTCAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSE-XLGRYLXATRDLKPGELILMEAPTIIAPMAVTP-PVCLSCYAPVDGRY-MCPL-CGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKE-RIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVT----------MSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPAG-FLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSI--GEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSN 473
            MA  E+   C +C+  A  +C  C + +YCSREHQK  W+ HK  C +Y+I +++  LGR L   RD+K G+LI+   P +I P    P P CL C+  +D +  +C   C +P+C+  C        EC++  +  SP K            E+V +LR   +K+ +   Y+ LI LE H  E +  + ++   +  +L+ ++E  S       D+++  L GI   NS E+  T              Q LY   SL+ HSCV NA    +    I +  A+PI     I+  Y  P+     RQ+ L E KFF C+C RC+DPTEL T  SS+ C  C       + D  NYE    C  C+ V + R    +  S+  G+  +     +   C+ F+K++   L   H +++ +K+ L  +    S    S++ E  +K  +++Q  C ++L V + I PG+S  RG+V++EL A     A  +F N
Sbjct:    1 MAGIEANKICEHCEAPAKLQCGACELVWYCSREHQKRKWRDHKMICIAYRIEDTQSALGRQLRTARDVKQGDLIISAPPCVIGPRLDYPKPSCLGCHVILDEKMSLCEGGCEYPLCSSECHRKFHSEEECKLLEKIKSPDKRC----------EIVTILRFALLKKSNPRIYEKLILLEDHVDEIKASSTRWKNIEEGVLKHLKEIKSDLDIE-EDQELERLVGIWITNSFELERTDQQLFGEKRAGESIQGLYDVPSLMNHSCVGNARLVINSGMYIDVYAAVPISNKAPITFNYISPLEDYDRRQKILKENKFFECKCERCEDPTELGTFSSSLLCQVCKKSPSTRTKDSKNYE----CRDCSEVMSERDAMKIANSLMKGKNKLHRIGKAWVTCIPFLKEYQDILWETHTFIIXIKMXLVXL--XXSNXAISQMDENGKKIQIERQSYCNDVLAVQDIIDPGMSLGRGLVLHELHAARVFLANYRFEN 474          

Query:   90 VCLSCYAPVDGR----YMCPLCGWPMCNEICRNSPA--HIPECRI--TAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPS--QALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPAGFLVSLDPF--NYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKG--SPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYEL 459
            VCL+CY  +        +C  CG P+C + C  S    H PEC    +++RG    +A+  N    L+EVV +LRCL++++   E +   + L  H  ER  +   +R        IR+         P E++L +CGIL  NS E+P+  SP   QA+Y+   L EH+C+    + F+ + ++++R ++ +K G+HI+I Y+D +W T+ R+ HLL +K F+C C RC+DPTE  +   ++ C  C  G ++  +P     E+ W C  C  V    F       + + +  +E G  +PE C  F+  +S+ L+  H +++DVK  L  ++G      G  + +L    L  K+ +   +L+VA KI PG+SRLRG  +YEL
Sbjct:  440 VCLNCYGSIQDENEDISVCSRCGLPLCGQ-CDESELNLHKPECHALSSSKRGKRTSLALLDNVSL-LFEVVLVLRCLHLRDIP-ENWSHFLGLTSHVGERRDSELEARALEASEXXIRDI----GIEIPREEVLNICGILDTNSFEIPLPSSPGTIQAIYKIGCLPEHNCIPTGHRCFESDLSLVLRASVDLKAGDHITITYTDSLWPTMERRTHLLYSKHFSCICERCRDPTEKGSFIGALNCLKCGVGRILPENPLEDKNETSWICIDCGYVSPQGFAEDTYNQVAQVIQGMESGEINPEQCNRFITLYSKILNSQHAHMLDVKHTLLHLLGHHE---GYLLGDLSNYLLQLKEDIARCLLQVAEKILPGISRLRGTTLYEL 813          

Query:  148 LYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREF--------FSVPSTRFP--DEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPAGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLE-KGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLR---GVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPT-CLQEGKLAAIARLDLVELETFMDSVESKKA 534
            LY+ +A LR L +++ S +K+  ++ LE H +ER K    +  K T+ +VI           F V   +F   D+ I  + GIL  N+ E+ +  S  QALY+   LLEHSC  N    FD   ++ +R    IK GEH+  MY+  +WGT+ R++HL   KFF C+C+RC+DP+E  ++ S++         L+   P      W     + V T   V + +  IG EL  L+  G+ +  + F+ K+   LH +H++L+  K +L QM+G+S    G  I +L EK     + LC ++++V   I P + RL+    V +YEL        ++K+ NG + ++  +  LQE + Y+ + + +   E    L EG +    +  L +L+ FM SV  ++A
Sbjct:   78 LYDAIAPLRILLLQKTSPKKFGKIMSLESHFEERKKADPPTAWKRTIEKVIDVMKKTLGIMVFEVLYKQFDFSDDTIQRINGILETNAIEIRLAASEIQALYELTCLLEHSCCPNIRMTFDDKYHVTVRAGRNIKAGEHLCFMYTHSLWGTMARREHLYLNKFFWCKCLRCEDPSEYGSNISTL---VREEKELLQRKPLEPNCPWTSRDGSVVITADEVMSEMSIIGAELALLQLNGTVDEYIQFIDKYEVFLHSNHYHLLTAKHSLLQMLGRSE---GHLIQDLPEK----MEDLCRQVIDVCKLIDPSIVRLQIYVAVALYELHLPLLQILKRKWENGGLPTEEFRKELQEPRDYITQALDLLKDEVNENLPEGVMRLTVKDTLSQLDLFMKSVGCEEA 469          

Query:   10 CAYCQIQANQRCTGCHVTFYCSR-EHQKLHWKKHKNR---CCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGR-YMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLR--VIREFFSVPSTRFPDEDILALCGILFVNSHEVPV----TMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPAGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQ---SSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQE---VKKYLQECIQIFS 500
            C YC   A   CT C +  +CS   H+ LH+   K+    C  + +  +  LGR+L ATRD+K  E+IL E+P +I P   +   CL C+  +D   + C  C +P C++ C   P H  EC    + G               Y ++  LR L ++E   E +  +++        I+  +Y+ +K T     V+++  S+       + +  L G++  N  ++ +           LY   S L HSCV N       +  I +R ++ I KGE I   Y  P   T+ R+  +    +F C C RC DPTE  ++  ++ C  C +  ++ ++P   ES+W C+ C++     +V  V+ S+GE L       P +    +      LHP+H+  ++ +L +  +IG    SS+  G     +    + +K++ C  ILEV + + PG ++ R  ++ EL           F+ G      +  ILQE    + YL     IFS
Sbjct:    7 CFYCGNPATASCTTCELVSFCSEPSHKALHYGHKKDETSFCFPFAVKRNSQLGRHLVATRDIKALEVILEESPLVIGPYISSNNQCLECFKTLDTSPHSCISCNYPFCSQECSQGPWHKIECSAFQKYGHKRD-----ENDNDFYSIITTLRLLSLQESKPEFWNTIMKDMLDHNSDIQ--EYTPEKWTSYEETVVKKIQSLTKGNADTDTLTRLIGVIDTNGADLNLPHDGKHGKGTGLYLIYSNLNHSCVCNTKTINFQDRRIEMRASVNISKGEQICNQYVRPNKCTLARRTTIKNKWYFDCCCKRCADPTECGSYLGALLCSSCKS-VVLPINPLETESNWACKGCSKEYDVEYVMGVLISVGESLEEATPYDPNSYEKILYDTQDLLHPNHYLRIEAELKVAALIGNIPTSSFSKG-----MPRPAVERKRQCCFHILEVLSLVDPGFNQWRVQILSELTKTKLYLVNIDFNAGLADKVEVFKILQEQQVFQYYLAYNQSIFS 501          

Query:   48 SYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGRYMCPL--CGWPMCNEIC---RNSPAHIPECRITAERGS--PIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEV-----------PVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIP----IKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPAGFLVSLDPFNYESDWKCETCNR--VETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSV 529
            SY+I      GRYL A++D++PGE IL E     +P   T P+CL CY  +  +  C +  CGWP+C+E C     +  H+ EC +        P   A       P Y+VV  +R L   +K S K+    +L  H ++  K   +     ++++ ++  F    T   DE+IL + GI + N   V           PV     + LY   SLL H C  N  +  +   +   R+ +     I KGE I+  Y D    T+ R++ L E+K F C C RC +  +     S + CP C   ++V      Y     C  C     E P+ +      + E L   E  + +A  SF+    + LHPH+   + +  +L    G+ S   G E   + EK L +K ++   +++       G+S  +G++ YEL        + +   G +  D  K+I Q+   +L+  +    YE     EG++ A A L LV L++F+  +
Sbjct:   28 SYRIKFDSKEGRYLVASKDIEPGEDILTEEALFWSPRYSTRPLCLVCYGYLYNKESCYICECGWPLCSEECLXXAKTSDHVLECSLYTSHSQLRPDVHAFNFLGVEPSYDVVGPVRLL--SKKGSSKWYMTWKLMSHLEDWKKIPGWIEAHHSVMKELKALF----TETTDEEILTIFGIFYTNDFGVRVNAGVDGNGNPVLCPKIRQLYTLTSLLSHDCEPNTFRVINSKVDKKFRLEVKAKRRISKGEKITGTYVDVFAPTIVRKKVLKESKLFDCTCKRCSEAQD-GVGGSDLVCPKC-QNYVVCQKDLTY----ICSGCKEPYPEGPKKLLKYYGDLEEILEDPESCTVQAYESFISTRKKELHPHNLIFIRLMYSLSGFYGRLS---GYEXPVMTEKMLRRKWEIGEVVMKALETFDLGISSYKGMIDYELHMPMIMLTKMELDAGYVEYDKAKDIFQKALTHLKASLSHLQYENPMSFEGQIYAGASLSLVPLDSFISQI 518          

Query:   48 SYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMA---VTPPVCLSCY----APVDGRYMCPL-CGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKAL-IRLEPHTKERIKNGK-----YSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRC--PGCPAGFLVSLDPFNYESDWKCETCNRV----ETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFY-LMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQ 460
            S+++ +S   GR + ATR++  GE +  E   ++ P A   +    C  CY       D   +CP  CG P+C+E CR+S  H  EC++   +  P++      +P  L  +++++RC ++ E S +   A+   ++ +  + ++        + R++  +    R   +  +  F             V+ HEV V     +AL+  A LL H C  NA+ HF+    I++     I  G  I++ Y+  +W T+ R+  L  TK F C+C+RCQDPTE  T+ S++ C   GC  G ++ +     + DW+C TC  V    +  ++ +  + +I   + S    S +  + F+ +      P   Y L++ KL +   + +  +       E   +++    +   E+L + +K+  G   L+ ++  E+Q
Sbjct:   43 SWRVADSPISGRGIFATREIAAGEELFREHTLLVGPTAHRSMNLRTCTLCYRLIPGSTDSAALCPAGCGLPVCSE-CRDSTRHDLECKL-FRKWKPLESQRI--EPRAL-RILSVVRCFFLDEASRKLLYAMQANMDRYYMQEVQRAADCFEHFPREQDMLDYFYRTICAFNTNAFESRS--------NVDGHEVLV-----RALFPLAGLLNHQCTPNAAHHFENGETIVVCATERIPAGAEITMSYAKLLWSTLARKIFLGMTKHFICKCVRCQDPTENGTYLSALFCREQGC-RGLVIPVQTRTLQPDWRCITCENVFPHAKMAKYQDFALNTINNRINSC---SVQDMIHFINELCPRFCPSSNYVLIEAKLNVIWRMTRFDHE------EYTPEEMGHMDRYREEVLAILHKLGAGECTLKKLITGEIQ 448          

Query:   48 SYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPV--CLSCYA--PVDGRYMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPL-YEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPST-RFPDEDILALCGILFVNSHEVPVTMSPSQALYQN----ASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRC--PGCPAGFLVSLDPFNYESDWKCETCNRV----ETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFY-LMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQ 460
            ++ I +S   GR + ATRD+  GELI  E   +  P A    +  C+ C+   P  G      C  P+C E C +S  H  EC     R  P  +     +  P+   ++  +R  ++     ++ + L+       ER     Y R+ +   +  R F   P+T R   + +  + G+L  N+ E P      + L +      +++ H C  NAS +F+     ++R A  I KG  I+  Y+  +WG + R   L  TK F C C+RC D TE  T+ S++ C   GC  G ++ +     + DW+C TC  V    +  ++ +  + +I   + S    S +  + F+ +      P   Y L++ KL +   + +  +       E   +++    +   E+L + +K+  G   L+ ++  E+Q
Sbjct:   56 NWTISSSTVAGRGVFATRDIAAGELIFQERALVTGPTARKGQLSSCICCHETLPQTGFLCRHRCTLPVC-ETCSDSEEHQAECE-HFRRWQPKDVDAEQEQVNPMSLRILTAVRVFHL----GKEQRHLVDAMQANAER----AYRREIIQAAQCFRNF---PTTDRVFMDQLFRIVGVLNTNAFEAPCRSGGHETLLRGLFPLTAIMNHECTPNASHYFENGRLAVVRAARDIPKGGEITTTYTKILWGNLTRNIFLKMTKHFACDCVRCHDNTENGTYLSALFCREQGC-RGLVIPVQTRTLQPDWRCITCENVFPHAKMAKYQDFALNTINNRINSC---SVQDMIHFINELCPRFCPSSNYVLIEAKLNVIWRMTRFDHE------EYTPEEMGHMDRYREEVLAILHKLGAGECTLKKLITGEIQ 462          

Query:   43 KNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPV-CLSCYAPVDGRYMCPLCG--WPMCNEICRNS--PAHIPECRITA--ERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMT-MLRVIREFFSVPSTRFPDEDILALCGILFVNSHEV-PVTMSPSQ-ALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQD-----PTELNTHFSSIRCPGCP-AGFLVSLDPFNYESDWKCETC 348
            ++RC    + N    GR L   RD +PGE+IL + P I  P   +    C  C+   +    C  C   W  C   C+ S    H  EC+     E+     +  TI     LY    L     +   +++ Y  +  L  H  E  +       +M  ++ +I +F SV      +      C     N+H +    + P    L+   S++ HSC  NA   F+    + +R    I K   I+I Y +    T+ RQ+ L E   F C+C RC +       E +      RC      GFL+  DP   E  + C+ C
Sbjct:    9 QDRCLG--VSNLPQKGRSLFTARDFRPGEVILSQKPYICVPNNTSSESRCDGCFK-TNNLKKCSACQVVW-YCGSSCQKSEWKLHRDECKALTRLEKEKRKFVTPTIRLMVRLYIKRNLQNEKVLPITTTDNYSLVEALVSHMSEIDEKQMLLYAQMANLVNLILQFPSVDLREIAENFSKFSC-----NAHSICDSELRPQGIGLFPLVSIINHSCSPNAVLVFEEQMAV-VRAMDNISKDSEITISYIETAGSTLTRQKSLKEQYLFHCQCARCSNFGKPHDIEESAILEGYRCANEKCTGFLLR-DP--EEKGFVCQKC 317          

Query:   58 GRYLXATRDLKPGELILMEAP-TIIAPMAVTPPVCLSCYAPVDGRYMCPLCGWP-MCNEICRNS--PAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCL--YMKEK--SSEKYKALIRLEPHTKERIKNGKYSRDK--MTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEV--PVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQ 309
            G  L A   L+PGEL+    P            VC  C    +    C  C     C+  C+    P H  EC       S +K   +    +P   V  L R +   M EK   SEK  +   LE +  +  ++ K    +  MT    +RE     S   P  D+      +  NS  +           LY + SLL HSC  N S  F+   ++L+R    I+ GE ++I Y D +  +  R++ L +   F C CIRCQ
Sbjct:   15 GNGLRAVAPLRPGELLFRSDPLAYTVCKGSRGVVCDRCLLGKEKLMRCSQCRIAKYCSAKCQKKAWPDHRREC-------SCLK---SCKPRYPPDSVRLLGRVIVKLMDEKPSESEKLYSFYDLESNISKLTEDKKEGLRQLAMTFQHFMREEIQDASQLPPSFDLFEAFAKVICNSFTICNAEMQEVGVGLYPSMSLLNHSCDPNCSIVFN-GPHLLLRAVREIEAGEELTICYLDMLMTSEERRKQLRDQYCFECDCIRCQ 267          

Query:   58 GRYLXATRDLKPGELILM-EAPTIIAPMAVTPPVCLSCYAPVDGRYMCPLCGWPM-CNEIC--RNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKS-SEKYKALIRLEPHTKERIKNGKYSRDKMTMLRV--IREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQ------ALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRC 308
            GR L  +R    GEL+    A + +  +     +C  C+    G   C  C     CN  C  +N P H  EC+     G   + + T+     +  ++A L+    KE+S SE    L  +E H  E + N K    +MT   +  + +F+S     FPD   L     LF   H    T+   +      A++ + +LL HSC  N    +    N  +R    I  G+ I   Y D ++ T +R + L +  +F+C C  C
Sbjct:   19 GRGLRVSRAYGVGELLFSCPAYSYVLSVGERGLICEQCFTRKKGLAKCGKCKKAFYCNANCQKKNWPMHKLECQAMCAFGENWRPSETVR---LVARIIARLKA--QKERSPSEILLLLGEMEAHL-EDMDNEK---REMTEAHIAGLHQFYS-KHLDFPDHQALL---TLFSQVHCNGFTVEDEELSNLGLAIFPDIALLNHSCSPNVIVTY-RGINAEVRAVKDISPGQEIYTSYIDLLYPTADRLERLRDMYYFSCDCKEC 268          

Query:   12 YCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGRYMCPLCGWPMC--NEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQ----ALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCP---AGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSVE 530
            +C  +A+QRC+GC   FYCSR+HQK  WKKH++ C +Y+I  +  +GR+L A RDLK G++IL E P ++ P      +CL CY+ VDGR  C  CGWPMC  ++   +   H  EC + A  G PI  ++    P   Y+ V +LRCL +++++ E++  L++LE H +ER + G    D+ T +R IRE   +   + P+E IL LCGIL VNS E P     SQ    A+Y  ASLLEH CV NA K F    +I+IR A+PI KGE I++ Y++P+WGT+NRQ+HL +TKFF C C RC+DPTEL+T  S   C  CP   AG L++ +P +  SDW C  C   +   +   +I S+G+E+++L+KGS   C  F++K S+ LHP+HFYL DVK+ALCQM G   +  G  + E+++  L  K+ L  E+L+VA+ +SPG++RLR +++YELQA  +   RK      IS + ++  ++ V+K LQE   IFS+EP    EG+LA I+  +L ++E F+ +++
Sbjct:    7 FCGKEAHQRCSGCQAVFYCSRDHQKSDWKKHRSHCKAYRIEQTLTVGRHLIACRDLKAGDVILQEKPIVMGPKHTAGQICLGCYSGVDGRTRCSQCGWPMCGRDDCHAHESDHAAECGVMASGGRPIVGSL----PVQAYQSVMVLRCLALRDQNPERWDELMQLEAHVQERRQKGMEDVDQATAVRFIRETLGL---QIPEELILQLCGILMVNSFEQPPMKGNSQHGLVAVYSTASLLEHDCVANAIKTFTNKGDIVIRAAVPIPKGEKIALCYTEPLWGTMNRQRHLSQTKFFQCVCERCKDPTELDTFTSGFYCQKCPQQSAGILLTENPLDDASDWICRQCGARQPANYAAEIIESVGKEIVALKKGSVRDCEGFLRKFSKVLHPNHFYLTDVKMALCQMYG---HLEGQSLIEMNDDTLNAKEALALELLKVADAVSPGMTRLRAILLYELQAVLSVRCRKLCLTQSISKEELQANVKVVRKMLQESSTIFSWEPEETDEGRLAIISSKELKDVELFLKTLD 524          

Query:   10 CAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDG--RYMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCP--GCPAGFLV--SLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSVESKKAIQ 536
            C  C+  A  +C  CH   YC ++HQ+ HWK+HK+ C  +KIC    LGR+L ATR LKPGE+++ EAP I  P   + PVCL C   VD      C  CGWP+C+++C  SP+HIPECR T++RG  I + +    P P+Y+ + +LRCLY K+   + +K L  L+ H +E      Y  D++T+   IR FF + +T F +EDI+ + G   VN HEVP+T     A+Y +AS+LEHSC  N +K F    +I+I  A  I++G+H+SI YSDP+WGT +R+  L ETKFF C C RC+DP+E  T+FS+I+C    C  G+L+  +        DW C+ C++  +   V+ ++  IG +L  L+K S E C  F+  H   LH +H+Y  +VK  L Q+IGQ        I  + ++DL  K + C  + ++   I+P   R  G++++E        AR+       +       L+E KK L E I++   EP  L EGK+   A   L +++T + +++SK+ ++
Sbjct:    7 CEVCEKPALHKCGKCHNAHYCDKKHQREHWKQHKSVCQPFKICEDAVLGRHLVATRALKPGEVVIQEAPLIWGPSYNSIPVCLGCGKAVDETCSRPCQKCGWPVCSDLCEKSPSHIPECRYTSQRGEKITVKI-FGVPHPIYKCITVLRCLYQKQFLPKNWKKLETLQNHLEEHKSTTNYESDRVTIAEFIRRFFKLSAT-FSEEDIMKVHGSTLVNGHEVPLTEPFHVAIYSSASMLEHSCGPNCTKSFTKQGHIVISAAKSIQEGDHLSICYSDPLWGTPSRRYFLHETKFFWCHCERCEDPSEFGTNFSAIKCSTKSC-GGYLLPATFTELQKLPDWVCDKCDKTMSFYSVHDILERIGRDLFDLDKSSIEDCKDFLNTHQDLLHENHYYCTEVKYTLSQLIGQRL------ILVISDEDLSLKLQYCNSLEKLLKIIAPAEKRALGLILFEKYVALTEIARR-------AGPQKITDLEEAKKILLETIELLKNEPDVLPEGKICKQAVQKLKDIDTALQTLKSKEDVK 523          

Query:    5 ESQFTCAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILME-APTIIAPMAVTPPVCLSCYAPVDGRYM--CPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVT-INKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCP-AGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSVESK 532
            ESQ TC  C   +  +C+ C   +YCS++HQK  WKKH   C S+K+  +  LGR+  ATR++K GE+IL +  P I   M  T PVCL CY  ++      C  CGWP+C    +N   H  EC+ ++ R    KI++T    P P Y+ + ++R L +K+ + E YK LI LE H  E       S++ + +   I+ FF   +    +E+I  + GIL VN HEVP+T SP  A+Y+ ASL+EH+C  N SK F     ++IR A+PI KG+HISI Y+DP+WGT NR+ HL +TKFF C C RCQDPTE  T F++++C     +G+++       E D+ C+ C  V +   +  V+  IG +L +++K    AC  F+ ++  +LHP+H+Y +DV +AL Q+IGQ + G       + E  L++K KLC ++  +   + P  +R+RG++++EL A  A  +R ++ N E     M ++LQE KKYL +  Q+  YEP  L EGK+A  A  +L E+   +     K
Sbjct:    2 ESQ-TCVICGGHSVHKCSACENVYYCSKKHQKEDWKKHSKICKSFKLAENPSLGRHYIATRNIKVGEIILRDDQPLITGLMYNTVPVCLQCYTVLNQEIAIPCEKCGWPLC----QNCNEHGLECKFSSSRRDS-KISITEFGYPHPSYQCINVIRALSLKDTNPESYKKLISLESHCNEM----NNSKEPLNIAHFIKRFFK--ADDISEEEIATIIGILQVNGHEVPLTDSPYVAVYEMASLIEHNCRANCSKSFTDMGGLIIRAALPITKGDHISICYTDPLWGTANRRHHLFKTKFFECICNRCQDPTEFQTMFNALKCNNINCSGYILPKTFLEQEQDYICKICESVVSCTEIEKVLEDIGIDLSNMKKNDIVACKEFLDRYKNDLHPNHYYNIDVTIALAQLIGQQTGGLAV----IEENLLIEKIKLCKKLDTLLKLLVPAENRIRGLILFELHAALAELSR-RYKNEET----MISLLQESKKYLIDGYQLLKYEPKILPEGKIAQHAEKNLEEITKLLKQFHMK 513          

Query:    5 ESQFTCAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILME-APTIIAPMAVTPPVCLSCYAPVDGRYM--CPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVT-INKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCP-AGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTG--------SEIF---------------ELHEKDLLQKQKLCTEILEVANK-------------ISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSVESK 532
            ESQ TC  C   +  +C+ C   +YCS++HQK  WKKH   C S+K+  +  LGR+  ATR++K GE+IL +  P I   M  T PVCL CY  ++      C  CGWP+C    +N   H  EC+ ++ R    KI++T    P P Y+ + ++R L +K+ + E YK LI LE H  E       S++ + +   I+ FF   +    +E+I  + GIL VN HEVP+T SP  A+Y+ ASL+EH+C  N SK F     ++IR A+PI KG+HISI Y+DP+WGT NR+ HL +TKFF C C RCQDPTE  T F++++C     +G+++       E D+ C+ C  V +   +  V+  IG +L +++K    AC  F+ ++  +LHP+H+Y +DV +AL Q+IGQ + G           +I                E   K L    +    + EV  +             ++   +R+RG++++EL A  A  +R ++ N E     M ++LQE KKYL +  Q+  YEP  L EGK+A  A  +L E+   +     K
Sbjct:    2 ESQ-TCVICGGHSVHKCSACENVYYCSKKHQKEDWKKHSKICKSFKLAENPSLGRHYIATRNIKVGEIILRDDQPLITGLMYNTVPVCLQCYTVLNQEIAIPCEKCGWPLC----QNCNEHGLECKFSSSRRDS-KISITEFGYPHPSYQCINVIRALSLKDTNPESYKKLISLESHCNEM----NNSKEPLNIAHFIKRFFK--ADDISEEEIATIIGILQVNGHEVPLTDSPYVAVYEMASLIEHNCRANCSKSFTDMGGLIIRAALPITKGDHISICYTDPLWGTANRRHHLFKTKFFECICNRCQDPTEFQTMFNALKCNNINCSGYILPKTFLEQEQDYICKICESVVSCTEIEKVLEDIGIDLSNMKKNDIVACKEFLDRYKNDLHPNHYYNIDVTIALAQLIGQQTGGLAVIEENLLIEKIKLCKKLDTLLKLLVPGEEFSKTLFVLNRFLRRLNEVGRQSIVLPISQHAWLSVNRAENRIRGLILFELHAALAELSR-RYKNEET----MISLLQESKKYLIDGYQLLKYEPKILPEGKIAQHAEKNLEEITKLLKQFHMK 553          

Query:    5 ESQFTCAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILME-APTIIAPMAVTPPVCLSCYAPVDGRYM--CPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVT-INKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCP-AGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTG--------SEIF---------------ELHEKDLLQKQKLCTEILEVANK-------------ISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSVESK 532
            ESQ TC  C   +  +C+ C   +YCS++HQK  WKKH   C S+K+  +  LGR+  ATR++K GE+IL +  P I   M  T PVCL CY  ++      C  CGWP+C    +N   H  EC+ ++ R    KI++T    P P Y+ + ++R L +K+ + E YK LI LE H  E       S++ + +   I+ FF   +    +E+I  + GIL VN HEVP+T SP  A+Y+ ASL+EH+C  N SK F     ++IR A+PI KG+HISI Y+DP+WGT NR+ HL +TKFF C C RCQDPTE  T F++++C     +G+++       E D+ C+ C  V +   +  V+  IG +L +++K    AC  F+ ++  +LHP+H+Y +DV +AL Q+IGQ + G           +I                E   K L    +    + EV  +             ++   +R+RG++++EL A  A  +R ++ N E     M ++LQE KKYL +  Q+  YEP  L EGK+A  A  +L E+   +     K
Sbjct:    2 ESQ-TCVICGGHSVHKCSACENVYYCSKKHQKEDWKKHSKICKSFKLAENPSLGRHYIATRNIKVGEIILRDDQPLITGLMYNTVPVCLQCYTVLNQEIAIPCEKCGWPLC----QNCNEHGLECKFSSSRRDS-KISITEFGYPHPSYQCINVIRALSLKDTNPESYKKLISLESHCNEM----NNSKEPLNIAHFIKRFFK--ADDISEEEIATIIGILQVNGHEVPLTDSPYVAVYEMASLIEHNCRANCSKSFTDMGGLIIRAALPITKGDHISICYTDPLWGTANRRHHLFKTKFFECICNRCQDPTEFQTMFNALKCNNINCSGYILPKTFLEQEQDYICKICESVVSCTEIEKVLEDIGIDLSNMKKNDIVACKEFLDRYKNDLHPNHYYNIDVTIALAQLIGQQTGGLAVIEENLLIEKIKLCKKLDTLLKLLVPGEEFSKTLFVLNRFLRRLNEVGRQSIVLPISQHAWLSVNRAENRIRGLILFELHAALAELSR-RYKNEET----MISLLQESKKYLIDGYQLLKYEPKILPEGKIAQHAEKNLEEITKLLKQFHMK 553          

Query:    5 ESQFTCAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILME-APTIIAPMAVTPPVCLSCYAPVDGRYM--CPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVT-INKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCP-AGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTG--------SEIF---------------ELHEKDLLQKQKLCTEILEVANK-------------ISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSVESK 532
            ESQ TC  C   +  +C+ C   +YCS++HQK  WKKH   C S+K+  +  LGR+  ATR++K GE+IL +  P I   M  T PVCL CY  ++      C  CGWP+C    +N   H  EC+ ++ R    KI++T    P P Y+ + ++R L +K+ + E YK LI LE H  E       S++ + +   I+ FF   +    +E+I  + GIL VN HEVP+T SP  A+Y+ ASL+EH+C  N SK F     ++IR A+PI KG+HISI Y+DP+WGT NR+ HL +TKFF C C RCQDPTE  T F++++C     +G+++       E D+ C+ C  V +   +  V+  IG +L +++K    AC  F+ ++  +LHP+H+Y +DV +AL Q+IGQ + G           +I                E   K L    +    + EV  +             ++   +R+RG++++EL A  A  +R ++ N E     M ++LQE KKYL +  Q+  YEP  L EGK+A  A  +L E+   +     K
Sbjct:    2 ESQ-TCVICGGHSVHKCSACENVYYCSKKHQKEDWKKHSKICKSFKLAENPSLGRHYIATRNIKVGEIILRDDQPLITGLMYNTVPVCLQCYTVLNQEIAIPCEKCGWPLC----QNCNEHGLECKFSSSRRDS-KISITEFGYPHPSYQCINVIRALSLKDTNPESYKKLISLESHCNEM----NNSKEPLNIAHFIKRFFK--ADDISEEEIATIIGILQVNGHEVPLTDSPYVAVYEMASLIEHNCRANCSKSFTDMGGLIIRAALPITKGDHISICYTDPLWGTANRRHHLFKTKFFECICNRCQDPTEFQTMFNALKCNNINCSGYILPKTFLEQEQDYICKICESVVSCTEIEKVLEDIGIDLSNMKKNDIVACKEFLDRYKNDLHPNHYYNIDVTIALAQLIGQQTGGLAVIEENLLIEKIKLCKKLDTLLKLLVPGEEFSKTLFVLNRFLRRLNEVGRQSIVLPISQHAWLSVNRAENRIRGLILFELHAALAELSR-RYKNEET----MISLLQESKKYLIDGYQLLKYEPKILPEGKIAQHAEKNLEEITKLLKQFHMK 553          

Query:   10 CAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVD-GRYM-CPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCP-----AGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSE-IFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFM 526
            C  C+ +A++RC+ C + +YC  EHQ+  WK HK  C  +KI ++E  GR+L ATRD+K GE++L E+P +  P  +T PVC+ C   ++  +Y+ C  CGWP+C   C++SP+H  EC+ T  RGS I I      P P Y+ +  +RCL + E    +++ L++LE H +ER  + ++  D+  + ++I  FF     ++ +++IL + GI+ VN HEVP+T   S A+Y  AS+LEHSC  N +K F     +++    PI++G+ +SI Y+D +W T NR +HL +TK F C C RC D TE  T+FS++RC G        G+L+ +D   +  +W+C  C++  +   V  ++     +L ++EK   + C  ++K +S+ L  +H Y++DVK++L Q+IG    G   E I ++  + L+ K K+C +++ +  KI P  +R  G   +EL A  A   R+       ++  ++  L++      ECI++  +EP+ L E K+ A AR++   L+  +
Sbjct:    2 CPVCKKEASKRCSRCAMVYYCCVEHQQQDWKVHKTTCQPFKIFSNEQYGRFLVATRDIKAGEIVLKESPLVHGPAQITGPVCVGCLQGLEEKKYLDCERCGWPVCKRSCQDSPSHQAECKFTIARGSKISIQ-HFYVPHPTYQCLMPVRCLLLAESDPARWETLLKLESHEEERRGSEQWRNDREGVAKLIPRFFKC-ENKWDEDEILRVVGIIQVNGHEVPMTEPSSVAIYNMASMLEHSCRPNLAKSFTNRGEVVMWAPNPIRRGDRLSICYTDVLWTTGNRLEHLQQTKMFRCECERCSDRTEYETYFSAVRCSGFQKDSKCKGYLLPVDNAQWTGEWQCLRCSKEVSGATVCQILERARMDLEAMEKHREDHCNRYMKHYSKWLTANHQYMVDVKISLSQVIG----GKNPEAIKKIPYEKLMNKIKICQDLIALFEKICPAEARAFGATRFELHAALAELGRRSTEANNPAAAAVQ--LEDSLYNANECIRMLLHEPSMLMESKICAQARINANTLKALL 518          

Query:    5 ESQFTCAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILME-APTIIAPMAVTPPVCLSCYAPVDGRYM--CPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVT-INKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCP-AGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTG--------SEIF---------------ELHEKDLLQKQKLCTEILEVANK-------------ISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSVESK 532
            ESQ TC  C   +  +C+ C   +YCS++HQK  WKKH   C S+K+  +  LGR+  ATR++K GE+IL +  P I   M  T PVCL CY  ++      C  CGWP+C    +N   H  EC+ ++ R    KI++T    P P Y+ + ++R L +K+ + E YK LI LE H  E       S++ + +   I+ FF   +    +E+I  + GIL VN HEVP+T SP  A+Y+ ASL+EH+C  N SK F     ++IR A+PI KG+HISI Y+DP+WGT NR+ HL +TKFF C C RCQDPTE  T F++++C     +G+++       E D+ C+ C  V +   +  V+  IG +L +++K    AC  F+ ++  +LHP+H+Y +DV +AL Q+IGQ + G           +I                E   K L    +    + EV  +             ++   +R+RG++++EL A  A  +R ++ N E     M ++L E KKYL +  Q+  YEP  L EGK+A  A  +L E+   +     K
Sbjct:    2 ESQ-TCVICGGHSVHKCSACENVYYCSKKHQKEDWKKHSKICKSFKLAENPSLGRHYIATRNIKVGEIILRDDQPLITGLMYNTVPVCLQCYTVLNQEIAIPCEKCGWPLC----QNCNEHGLECKFSSSRRDS-KISITEFGYPHPSYQCINVIRALSLKDTNPESYKKLISLESHCNEM----NNSKEPLNIAHFIKRFFK--ADDISEEEIATIIGILQVNGHEVPLTDSPYVAVYEMASLIEHNCRANCSKSFTDMGGLIIRAALPITKGDHISICYTDPLWGTANRRHHLFKTKFFECICNRCQDPTEFQTMFNALKCNNINCSGYILPKTFLEQEQDYICKICESVVSCTEIEKVLEDIGIDLSNMKKNDIVACKEFLDRYKNDLHPNHYYNIDVTIALAQLIGQQTGGLAVIEENLLIEKIKLCKKLDTLLKLLVPGEEFSKTLFVLNRFLRRLNEVGRQSIVLPISQHAWLSVNRAENRIRGLILFELHAALAELSR-RYKNEET----MISLL-ESKKYLIDGYQLLKYEPKILPEGKIAQHAEKNLEEITKLLKQFHMK 552          

Query:    5 ESQFTCAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILME-APTIIAPMAVTPPVCLSCYAPVDGRYM--CPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVT-INKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCP-AGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYG 414
            ESQ TC  C   +  +C+ C   +YCS++HQK  WKKH   C S+K+  +  LGR+  ATR++K GE+IL +  P I   M  T PVCL CY  ++      C  CGWP+C    +N   H  EC+ ++ R    KI++T    P P Y+ + ++R L +K+ + E YK LI LE H  E       S++ + +   I+ FF   +    +E+I  + GIL VN HEVP+T SP  A+Y+ ASL+EH+C  N SK F     ++IR A+PI KG+HISI Y+DP+WGT NR+ HL +TKFF C C RCQDPTE  T F++++C     +G+++       E D+ C+ C  V +   +  V+  IG +L +++K    AC  F+ ++  +LHP+H+Y +DV +AL Q+IGQ + G
Sbjct:    2 ESQ-TCVICGGHSVHKCSACENVYYCSKKHQKEDWKKHSKICKSFKLAENPSLGRHYIATRNIKVGEIILRDDQPLITGLMYNTVPVCLQCYTVLNQEIAIPCEKCGWPLC----QNCNEHGLECKFSSSRRDS-KISITEFGYPHPSYQCINVIRALSLKDTNPESYKKLISLESHCNEM----NNSKEPLNIAHFIKRFFK--ADDISEEEIATIIGILQVNGHEVPLTDSPYVAVYEMASLIEHNCRANCSKSFTDMGGLIIRAALPITKGDHISICYTDPLWGTANRRHHLFKTKFFECICNRCQDPTEFQTMFNALKCNNINCSGYILPKTFLEQEQDYICKICESVVSCTEIEKVLEDIGIDLSNMKKNDIVACKEFLDRYKNDLHPNHYYNIDVTIALAQLIGQQTGG 404          

Query:   10 CAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGR--YMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCP-AGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFM 526
            C  C+     +C+ C+   YCS +HQK  WK HK  C  +KI ++E LGR+L ATR +KP E++L EAP +  P  ++ PVCL C   ++      C  CGWP+C   C++   H  EC +T +RG  + +      P PLY  ++ +RCL + E S+EK      LE     R  + ++  D +++ + I +FF   + +F +E+I+   G L +N HEVP T     A++  AS  E+SC+ N +K F+ N + ++     IKK  H+SI YSD +WGT +RQ+HL++TK F C C RC D TEL+T++S+I+C      G ++      +   W+C  C++     +V  ++   G+++ S+EK + E  L ++K + + L P HF++ ++K+ L Q++ +       E+  + +  LL K     E++E+  K++P   R  G + +EL +  A   R+      +S    K+ L+E   Y+ +C+    YE     EG +   A+++   L   M
Sbjct:    4 CHVCEEPTKNKCSNCNQVSYCSVQHQKQDWKVHKPSCHPFKIAHNEQLGRHLVATRTIKPYEIVLKEAPLVRGPAQISAPVCLGCLNGIEAEDHIECEQCGWPLCGPECKSLDEHKAECGLTKDRGQKVNVQ-EFGGPHPLYTCLSTVRCLLIGETSTEKASKFQDLESLESTRRGSNQWKADLVSIGQFIPKFFK--TQKFTEEEIMKAVGALQINGHEVPTTDPSHVAVFYTASFTENSCLPNLAKSFNKNGHCILWAPREIKKNAHLSICYSDAMWGTADRQRHLMQTKLFKCACERCVDVTELDTNYSAIKCEDRQCGGLMLPTKADEWNGSWRCRECHKQVQKHYVERILERAGKDIQSMEKIA-ENGLKYLKHYEKWLPPQHFHMSEIKILLVQLLAKDQ----KELMVIPDDRLLLKLNFARELVELYEKLTPCEVRTLGTLCFELHSAIAEQTRRVALETSLSP---KDRLEESLFYVDKCVNYLKYESDIFIEGHVLKQAKINRDALRMVM 512          

Query:   12 YCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGRYMCPLCGWPMCNEI-CR-NSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQ----ALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCP--AGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSVE 530
            +C  +A QRC+GC   FYCSREHQK  WKKH++ C +Y++  +  +GR L A RDLK G++IL E P ++ P      VCL CY+ VDGR  C  CGWP C  + C  N   H  EC + A  G PI  ++    P   Y+ V +LRCL +K+++  +++ L++LE H  ER + G    D+ T +R+IRE   +     P+E IL LCGIL VNS E P   + S     A+Y  ASLLEH CV NA K F  N +I+IR A+PI KG+ I++ Y++P+WGTVNRQ+HL +TKFF C C RC+DPTEL+T  S + C  CP  +G L+  +P +  SDWKC  C   +   +V  +I S+G+E+++L+KGS + C  F++K S+ LHP+HFYL DVK+ALCQM G   +  G  + E+++  L+ K+ L  E+L+VA+ +SPG++RLR +++YELQA  +   RK      IS + ++  ++ V+K LQE   IFS+EP    EG+LA I+  +L ++E F+ +++
Sbjct:   16 FCGKEALQRCSGCQSVFYCSREHQKADWKKHRSNCRAYRVERTLNVGRRLIACRDLKAGDVILQEKPLVMGPKYTAGQVCLGCYSSVDGRTKCSQCGWPTCGRVECHTNDSDHAVECGLIASGGRPIVGSL----PVQAYQSVMVLRCLALKDQNPGRWEELLQLESHVHERRQRGLEDVDQATSVRLIRETLGLD---VPEELILQLCGILMVNSFEQPPLKANSPQGLVAVYSTASLLEHDCVANAIKTFTNNGDIVIRAAVPISKGDKIALCYTEPLWGTVNRQRHLSQTKFFQCVCERCKDPTELDTFISGLYCQKCPQQSGILLIENPTDDASDWKCRQCGTRQPANYVAEIIESVGKEIVALKKGSLKDCEVFLRKFSKILHPNHFYLTDVKMALCQMYG---HLEGQSLIEMNDDTLIAKEALALELLKVADAVSPGLTRLRAILLYELQAVLSVRCRKLCVTQSISKEELQANVKVVRKMLQESSTIFSWEPEETDEGQLAVISAKELRDVELFLKTLD 532          

Query:   12 YCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGRYMCPLCGWPMC--NEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQ----ALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCP---AGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSVE 530
            +C  +A+QRC+GC   FYCSR+HQK  WKKH++ C +Y+I  +  +GR+L A RDLK G++IL E P ++ P      +CL CY+ VDGR  C  CGWPMC  ++   +   H  EC + A  G PI  ++    P   Y+ V +LRCL +++++ E++  L++LE H +ER + G    D+ T +R IRE   +   + P+E IL LCGIL VNS E P     SQ    A+Y  ASLLEH CV NA K F    +I+IR A+PI KGE I++ Y++P+WGT+NRQ+HL +TKFF C C RC+DPTEL+T  S   C  CP   AG L++ +P +  SDW C  C   +   +   +I S+G+E+++L+KGS   C  F++K S+ LHP+HFYL DVK+ALCQM G   +  G  + E+++  L  K+ L  E+L+VA+ +SPG++RLR +++YELQA  +   RK      IS + ++  ++ V+K LQE   IFS+EP    EG+LA I+  +L ++E F+ +++
Sbjct:    7 FCGKEAHQRCSGCQAVFYCSRDHQKSDWKKHRSHCKAYRIEQTLTVGRHLIACRDLKAGDVILQEKPIVMGPKHTAGQICLGCYSGVDGRTRCSQCGWPMCGRDDCHAHESDHAAECGVMASGGRPIVGSL----PVQAYQSVMVLRCLALRDQNPERWDELMQLEAHVQERRQKGMEDVDQATAVRFIRETLGL---QIPEELILQLCGILMVNSFEQPPMKGNSQHGLVAVYSTASLLEHDCVANAIKTFTNKGDIVIRAAVPIPKGEKIALCYTEPLWGTMNRQRHLSQTKFFQCVCERCKDPTELDTFTSGFYCQKCPQQSAGILLTENPLDDASDWICRQCGARQPANYAAEIIESVGKEIVALKKGSVRDCEGFLRKFSKVLHPNHFYLTDVKMALCQMYG---HLEGQSLIEMNDDTLNAKEALALELLKVADAVSPGMTRLRAILLYELQAVLSVRCRKLCLTQSISKEELQANVKVVRKMLQESSTIFSWEPEETDEGRLAIISSKELKDVELFLKTLD 524          

Query:   12 YCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGRYMCPLCGWPMCN--EICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQ----ALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCP--AGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSVE 530
            +C  +A QRC+GC   FYCSREHQK  WKKH++ C +Y++  +  +GR L A RDLK G++IL E P ++ P      VCL CY+ VDGR  C  CGWP C   E   N   H  EC + A  G PI  ++    P   Y+ V +LRCL +K+++  +++ L++LE H  ER + G    D+ T +R+IRE   +     P+E IL LCGIL VNS E P   + S     A+Y  ASLLEH CV NA K F  N +I+IR A+PI KG+ I++ Y++P+WGTVNRQ+HL +TKFF C C RC+DPTEL+T  S + C  CP  +G L+  +P +  SDWKC  C   +   +V  +I S+G+E+++L+KGS + C  F++K S  LHP+HFYL DVK+ALCQM G   +  G  + E+++  L+ K+ L  E+L+VA+ +SPG++RLR +++YELQA  +   RK      IS + ++  ++ V+K LQE   IFS+EP    EG+LA I+  +L ++E F+ +++
Sbjct:   53 FCGKEALQRCSGCQSVFYCSREHQKADWKKHRSNCRAYRVERTLNVGRRLIACRDLKAGDVILQEKPLVMGPKYTAGQVCLGCYSSVDGRTKCSQCGWPTCGRAECHTNDSDHAVECGLIASGGRPIVGSL----PVQAYQSVMVLRCLALKDQNPGRWEELLQLESHVHERRQRGLEDVDQATSVRLIRETLGLD---VPEELILQLCGILMVNSFEQPPLKANSPQGLVAVYSTASLLEHDCVANAIKTFTNNGDIVIRAAVPISKGDKIALCYTEPLWGTVNRQRHLSQTKFFQCVCERCKDPTELDTFISGLYCQKCPQQSGILLIENPTDDASDWKCRQCGTRQPANYVAEIIESVGKEIVALKKGSLKDCEVFLRKFSTILHPNHFYLTDVKMALCQMYG---HLEGQSLIEMNDDTLIAKEALALELLKVADAVSPGLTRLRAILLYELQAVLSVRCRKLCVTQSISKEELQANVKVVRKMLQESSTIFSWEPEETDEGQLAVISAKELRDVELFLKTLD 569          

Query:    9 TCAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGRYMCPL--CGWPMCNEICRNSPAHIPECRITA-ERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRC-PGCPAGFLVSLDPFNYESD-----WKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSVES 531
            TCA C   ANQRC GCHV +YC R+HQ+L WK H++RC  +K+ +++ LGR+L ATRD+K GE+IL E P +  P  VTPPVCL CY  +  +  C    CGWPMC+E C  +PAH  EC IT  ++GS + +   + +P P+Y+ V  LRCLY+++    K++ L  LE H +ER K  +Y  D++T+ + +R FF +    F  E+IL +CGIL VN HEVPVT  P  A+Y  ASLLEHSC  N SK F  +  ++I    PI KG+H+SI Y+D +WGT NR+ HL ETKFF CRC+RC DPTE  T+FS++RC      G+LV  +    +SD     W+C  C+  ET   V +V+  +G  L S++KG P  C  F+ + S  LHP+H+YL DV+LAL Q+ GQ+S      +  + ++DL +K  LC ++LE+ N + P   R+RGV+M+EL A  A  AR+  + G++    +++ L E K+ L E   + S+EP  L EGK+A  AR +L +L T + ++ +
Sbjct:   11 TCAVCTEPANQRCGGCHVIYYCCRDHQRLDWKGHRSRCKPFKVADNKALGRHLIATRDIKVGEVILDEQPLVAGPSQVTPPVCLGCYRILTEQSACACLDCGWPMCSEDCARTPAHRAECDITKLKKGSKVTVRNFL-QPHPIYQCVTTLRCLYLRDSDPVKWERLQSLESHCEERKKTRRYEDDRVTVAQFLRHFFHLQD--FEQEEILRVCGILQVNGHEVPVTDPPHVAVYDQASLLEHSCRPNCSKSFTPDGGLIIHALEPILKGQHLSICYTDALWGTANRRHHLAETKFFWCRCVRCADPTEFGTYFSAVRCLSKTCDGYLVPENSLLEDSDLGTTIWRCGRCSVSETAPRVLSVLERVGSALSSMQKGDPRVCEHFLAQFSPELHPNHYYLTDVRLALAQLYGQTS---DVGLVGISDQDLSEKASLCRQVLELMNTLVPAEHRVRGVLMFELHAAVAEVARRASNRGQLDPMALRDSLLESKRLLTEASFLLSHEPETLPEGKIALQARKNLTDLNTLLQNIHA 536          

Query:   12 YCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGRYMCPLCGWPMCN--EICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQ----ALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCP--AGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSVE 530
            +C  +A QRC+GC   FYCSREHQK  WKKH++ C +Y++  +  +GR L A RDLK G++IL E P ++ P      VCL CY+ VDGR  C  CGWP C   E   N   H  EC + A  G PI  ++    P   Y+ V +LRCL +K+++  +++ L++LE H  ER + G    D+ T +R+IRE   +     P+E IL LCGIL VNS E P   + S     A+Y  ASLLEH CV NA K F  N +I+IR A+PI KG+ I++ Y++P+WGTVNRQ+HL +TKFF C C RC+DPTEL+T  S + C  CP  +G L+  +P +  SDWKC  C   +   +V  +I S+G+E+++L+KGS + C  F++K S  LHP+HFYL DVK+ALCQM G   +  G  + E+++  L+ K+ L  E+L+VA+ +SPG++RLR +++YELQA  +   RK      IS + ++  ++ V+K LQE   IFS+EP    EG+LA I+  +L ++E F+ +++
Sbjct:  111 FCGKEALQRCSGCQSVFYCSREHQKADWKKHRSNCRAYRVERTLNVGRRLIACRDLKAGDVILQEKPLVMGPKYTAGQVCLGCYSSVDGRTKCSQCGWPTCGRAECHTNDSDHAVECGLIASGGRPIVGSL----PVQAYQSVMVLRCLALKDQNPGRWEELLQLESHVHERRQRGLEDVDQATSVRLIRETLGLD---VPEELILQLCGILMVNSFEQPPLKANSPQGLVAVYSTASLLEHDCVANAIKTFTNNGDIVIRAAVPISKGDKIALCYTEPLWGTVNRQRHLSQTKFFQCVCERCKDPTELDTFISGLYCQKCPQQSGILLIENPTDDASDWKCRQCGTRQPANYVAEIIESVGKEIVALKKGSLKDCEVFLRKFSTILHPNHFYLTDVKMALCQMYG---HLEGQSLIEMNDDTLIAKEALALELLKVADAVSPGLTRLRAILLYELQAVLSVRCRKLCVTQSISKEELQANVKVVRKMLQESSTIFSWEPEETDEGQLAVISAKELRDVELFLKTLD 627          

Query:   10 CAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGRYM--CPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCP--GCPAGFLVSLDPFNYESD--------WKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNG--EISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSV 529
            CA CQ  A Q+C+GCH+ +YCS+EHQK +WK HK  C  +KI N   +GR+L ATR+LKPG++IL E P +  P  VT PVCL C   ++ +    C  CGWPMC+EIC+NSP+HIPEC  T  RG  + I+V  + P P Y+ + +LRCL+ K+  S  +K +  LE H + R    KY ++K+T++  I+ FF + S  F DEDIL +CGI+ VN+HEVP+T  P  A++   S+ EHSC  N SK F  N ++LI   + IKKGEH+SI Y+DP+WGT NR+ HL +TKFF C C RCQD TE  T+FS+++CP   C    L    P  ++ D        W C TCN       V  +++  G  L  + KG+  AC  F+    + LHP+H+YL DVK AL Q++GQ  +G    + ++ ++DL  K  +C ++ E+ANKI+P  +R++G++++EL A      R++ ++G  E   D++   L + KKYL + I+    E   + EG++   AR +L +++  + +V
Sbjct:    7 CAVCQKPAQQKCSGCHLVYYCSKEHQKDNWKLHKIDCKPFKISNDPNVGRHLIATRNLKPGDVILKEPPIVWGPSQVTIPVCLGCGKGLNAKTSKPCQKCGWPMCSEICQNSPSHIPECSYTVNRGDKVNISV-FDIPNPSYQCITVLRCLHSKQFLSNVWKKIDALESHCEARKGTDKYEQEKITVVAFIKRFFKLDS--FEDEDILRICGIIMVNAHEVPLTDPPYVAIFNTTSMFEHSCHANCSKTFTANGHVLITAGVDIKKGEHLSICYTDPLWGTANRRHHLQQTKFFWCSCSRCQDVTEFGTNFSALKCPKKDCKGYAL----PKTFKEDNLELSDKSWFCTTCNYEVGAGEVGGILQDCGTNLSGIRKGNSNACKVFISNSLKFLHPNHYYLTDVKFALSQLLGQEFHGG---LPKISDEDLQLKIDICRQLTELANKIAPAENRIKGLLLFELHAAIMELGRRRGNSGTEESGPDYLYTKLIDSKKYLVQSIEALKNESEVMPEGQICIQARRNLKDIDVLLKTV 530          

Query:   10 CAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGRYM--CPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRC--PGCPAGFLVSLDPFNYES-----DWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIG-QSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFM 526
            C  CQ  A+Q+C+GCH  FYCSREHQ+  WKKHK  C  YKIC+ E LGR+L AT+D+  G+++L E P I  P  VT PVCL C   +D +    C  CGWP+C+  C  SP HIPEC+ T+ RGS I I+ T     P Y+ V +LRCLY K+  SE +K +  L+ H  ER    KY +D++++ + I  FF +    F +E+IL +CGIL VN HEVP+T  P  A+Y+ AS+LEH C  N ++ F     +L++    IKKG+H+SI Y+DP+WGT+NR+ HL E+KFF C C RC DPTE  T+FS+IRC  P C +G+++     +  +     +W C  C           ++  IG++L  +EKG+ +A   F+K + + LH +H+YL+DVKLAL Q++G + ++G  +    + + DL  K +LC  I  +   ++PG SRLRG++++EL A  A   R+     ++ +     +LQE KK LQE   +  +EP CL EGKL   A+ +L E++  +
Sbjct:    7 CQVCQSAASQKCSGCHTVFYCSREHQRADWKKHKKMCKPYKICHDEALGRFLIATKDISVGDIVLQEPPLIRGPSQVTMPVCLGCGNAIDEKNFKPCAKCGWPVCSSTCEKSPNHIPECQYTSSRGSKITIS-TFGSIHPSYQCVTVLRCLYQKQFLSETWKKIDLLQSHCAERKLTSKYEKDRVSIAQFILNFFKLRQV-FTEEEILRVCGILMVNGHEVPLTNPPHVAIYEIASMLEHKCNANCNRTFTSQGAVLVKAGTAIKKGDHLSICYTDPLWGTLNRRHHLYESKFFWCLCERCADPTEFGTYFSAIRCQKPNC-SGYILPSSFLDQSANGKLPNWTCNKCESSCNSYHAQEILDRIGQDLHEMEKGTTKAAKDFIKTYEKYLHSNHYYLVDVKLALSQLMGHEDAFGLPA----VGDDDLQYKARLCQGIANLVKTLAPGESRLRGLLLFELHATVAELGRRNADPQQLPA-----VLQESKKLLQESCDLLRHEPDCLPEGKLYIQAQKNLKEIDVVL 521          

Query:    4 AESQFTCAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGRYM--CPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPA-GFLVS---LDPFNYE--SDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSV 529
            +E    C  CQ  A+Q+C  CH  FYC +EHQK  WK HK  C  +K+C  E LGR+L ATRD+KPGE++L E P I  P  VT PVCL C   V  +    C  CGWP+CNE C  +P HIPECR T  RG  + +        P+Y+ + +LRCLY K+   E +K L  L+ H +ER    KY ++K+T+ + I  FF + +  F +E+I+ +CGI+ +NSHEVP+T  P  A+Y++ S+ EH+C  N +K F     +L+     IKKG+++ I Y+DP+WGT NR+ HL ++KFF C C RCQD TE  T FSS++C   P  G+L+    ++  N E  SDW C  C  V +      ++  IG++L  + KG  + C +F+K +   LHP+HFYL DV+LAL Q+IGQ   G    +  + ++DL  K +LC  ++ +   + PG +R+RG++M+EL A  A   R+K   G++ +     +L E K  L E   +  +EP  + EGK+   A  +L ELE  + +V
Sbjct:    2 SEESGECDICQKPASQKCGACHSVFYCCKEHQKSGWKTHKKVCRPFKVCYDEILGRHLKATRDIKPGEVVLQEPPLIWGPAQVTVPVCLGCGNAVTEKNSRPCFKCGWPVCNETCEKAPGHIPECRYTVLRGDRVSVK-NFGVVHPIYQCITVLRCLYQKQFLPEVWKKLDTLQSHCEERKGTQKYEQEKVTIAQFILRFFKLANV-FTEEEIMRVCGIVMINSHEVPLTEPPHVAIYESTSMFEHNCSANCTKSFTNKGGVLVAAGTHIKKGDNLCICYTDPLWGTSNRRHHLYQSKFFWCNCKRCQDTTEFGTFFSSLKCQNSPCNGYLLPKTFIENNNNEKGSDWTCTKCTNVFSAYSAQDLLERIGKDLSDMPKGVSQECKNFIKDYESLLHPNHFYLTDVRLALSQIIGQEGQGG---LPAVSDEDLELKARLCQGLVNLFKTLIPGETRVRGLLMFELHASIAEIGRRKGDPGDLHT-----LLLESKNVLTEAADLLKHEPDFIPEGKIYKQAVSNLKELEFVLRTV 525          

Query:   10 CAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGRYM--CPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPA-GFLVSLDPFNYES-----DWKCETCNRVETPRFVNA-----VIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSV 529
            C  C   A Q+C GCH+ +YCS+EHQK  WK+HK +C  +K+C  + LGRY+ ATRD+K GE++L E   I  P   + PVCL C   +  +    C  CGWPMC+E C  +PAHIPECR T  RG  + +        P+Y+ + +LRCLY K+   + +K L +LE H +ER ++ KY  +++T+ + I +FF + +T F +++I+ +CGIL VN HE+P++  P   L+ + S+ EH+C  N  K F     ILI   I I+KG+H+SI Y+DP+WGT NR+ HL +TKFF C+C RC D TE  T+FS+++C      G+L+     + E      DWKC  C     P F+NA     ++   G++L  LEKG+  +C  F+  +   LHP+H+Y+ DVK+AL Q++GQ   G    +  L + DLL K  LC  +  +   + PG SR+RG++++EL A  A   R+K     +  D +   L E K+ L E   +  +EP CL EGKL   A+++L+++E  + +V
Sbjct:    7 CDICAKPALQKCGGCHIVYYCSKEHQKNGWKQHKRQCKPFKVCQDDILGRYVVATRDIKAGEIVLQEPALIWGPSQTSVPVCLGCGNAITEKNCKPCTKCGWPMCSETCEKAPAHIPECRYTVLRGDKVTVK-NFGIIHPIYQCITVLRCLYQKQFLPDVWKKLEKLESHCEERKRSPKYENERITVGQFILKFFKLENT-FTEDEIMKICGILMVNGHEIPLSDPPHVGLFHSCSMFEHNCRPNCKKSFTNKGEILISSGIKIEKGQHLSICYTDPLWGTPNRRYHLFQTKFFWCKCERCCDVTEFGTNFSTMKCQNSECNGYLLPKSFIDDEENGKIVDWKCSKC-----PGFMNAYSIQDIMERAGKDLSLLEKGNSNSCKDFISTYESYLHPNHYYMTDVKIALTQILGQEYEGG---LPNLSDDDLLLKANLCQGLNNMLKILIPGESRVRGLLLFELHAAIAEIGRRK---ALVDPDELHRTLLESKRILLEAADLLKFEPDCLPEGKLYKQAQMNLLQIEHVLKTV 526          

Query:    3 EAESQFTCAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCY--------APVDGRYM----CPLCGWPMC-NEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHT-KERIKNGKYS---------------------------RDKMTMLRVIREFFSVPSTRFPDED-ILALCGILFVNSHEVPVTMSPSQ------ALYQNASLLEHSCVNNASKHFDM-NCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPG---CPAGFLVSL----DPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEK--GSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSVESKK 533
            + +S+  CA C   AN RC GC    YC++EHQK HWK HK  CC++K+C S  LGRYL A RD+K GE+IL E P ++ P  VTP +CL CY          V   Y+    CP CGWPMC N+ C NSP H  EC I   RG    +    N   P+Y  + +LR L +K++  +KY+ L+ L+ H+ K+R+++ K +                           RDK+  ++V+R FF        DED IL L  I+  N HE+P+  +          +Y N S LEH+C  N  K FDM +  I+IR A+PIKKG ++SI Y DP+WGT +R   L  TK+FTC+C RC+DPTEL  H SS+RC     C    L SL    DPF  E DW C  C       +V++++  IG+++  L +  G   A   FVKK S+ L P HFYL+++K+ L Q+ G++       I  L  + LL+K +LC E+L V NKI PG +RLRG++ YELQA     ++ KF+ GEI  D   + L +  K++ E I++  +EP    E + A  A  DL  L++ + S++  +
Sbjct:    7 DKKSEDQCALCNATANSRCGGCSKVSYCTKEHQKKHWKIHKGECCAWKVCESTSLGRYLTAVRDIKAGEVILRERPILLTPPKVTPAICLGCYREFNTDPEEQVQREYVEPRPCPKCGWPMCQNDECINSPEHAAECAIAEARGG--AVIRDFNVDHPVYRSIGILRVLGLKDRHPDKYQKLLNLQSHSEKQRLEDAKAADSSSLHSNAAALGRFGGEYPEQRSEIERDKVVTVKVVRGFFQRKDV---DEDTILNLISIIETNGHEIPIPNARGHINRRLIGVYNNTSFLEHNCKPNCVKTFDMADKAIVIRSAVPIKKGTNLSISYVDPLWGTNDRCNFLQMTKYFTCKCTRCRDPTELGAHVSSLRCQSLKCCEKTGLESLVIPEDPFAPEKDWVCIACKETYPVGYVSSIVNKIGKDMDELHEKFGDIPAIEEFVKKSSKFLSPFHFYLLEMKVELAQLYGRTP---DEPILALAPRKLLRKIQLCEELLIVLNKIYPGYNRLRGIITYELQAAVCTLSKMKFAAGEIPLDKHLDELMQCGKWMTEVIKVLGWEPENSIEKQRADGAAQDLQLLKSMVLSIQGDQ 587          

Query:    1 MAEAESQFTCAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGRYMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINK-PFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPA---GFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEI-----FELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSVESK 532
            +AE E + +CA+C   ANQRCTGCHVTFYCSREHQK HWKKHK  CC++KIC+S  +GR++ ATRDL+PGEL+L E P +IAPMA T P+CL+C+ PVDG   C  CGWPMC+++C  S  H+PEC +   RG PI   V  N  P P+YE +A LRC+Y+K+ + + ++ L++LE H ++R  NG+  +D++ +L++IR FF++ ++   D+++L L GILFVNSHEVPVT +P  ALY N+SL+EH+CV+NASKHFD + ++ IR A+ I+KG+HI+I YSDP+WG  NRQQHL+E+KFF C C RCQDP EL T+FSS+RCP CPA   G+L S++P +  S + C+ C+  E+  +VNAVIRSIGEEL+ LEKG+PEACL+F+KKHSQNLH +HFYLMDVKLALCQ+IG++      +      F   EKDL+ KQKLC E++ +AN ISPG+SRLRGV++YELQ+  A YARKKF+  EI+ DH KNI+QEV++YL ECIQIFS+E  C+QEG+LA++ARL L E+E  + S ++K
Sbjct:    4 LAEIE-KISCAFCNGDANQRCTGCHVTFYCSREHQKQHWKKHKTNCCAFKICSSSVIGRHVVATRDLRPGELVLSENPLLIAPMAYTVPICLACFKPVDGSIRCTTCGWPMCSDLCIGSSNHVPECTLNNSRGKPIPDEVGSNSVPNPIYEAIATLRCIYLKQSNPDVFEKLMQLEAHAEKRKLNGRVDKDQI-ILKMIRRFFNISASLISDDEVLDLQGILFVNSHEVPVTPTPVLALYLNSSLIEHNCVSNASKHFDTDGSLQIRAAVHIRKGDHIAITYSDPMWGNANRQQHLMESKFFQCICNRCQDPLELGTNFSSLRCPSCPAQANGYLSSINPLDIHSPFSCDHCHCEESADYVNAVIRSIGEELVQLEKGNPEACLTFIKKHSQNLHRNHFYLMDVKLALCQLIGKNLDTVEDQSNTVMDFRTREKDLIIKQKLCMELISIANIISPGISRLRGVILYELQSTLAIYARKKFAAKEITLDHFKNIIQEVRRYLIECIQIFSFESECIQEGRLASVARLKLAEVEDQLSSFDTK 542          

Query:   49 YKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGRYMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQ---ALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSD---PIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPAGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELETFMDSVESKK 533
            Y+I   + +GRY+ A R++ PGE+I  + P  + P   + P+CL C+  V+G Y CP C WPMC E C   P H  EC I  +R + + +    +KP   Y+ +  +R L++K  + + Y  +  L  H  +  +     R +  ++  IR+   +    F +E++  + GIL VNS  V  T   +     LY   S++ H+CV+N       + + +      I++GE I   Y      ++GT  R++ L  T  F C C RCQDPTE  T  S++ C GC  G+L+ + P ++ES W+C  C        V A ++   +EL +++     +    +++    LH +H++++DVK  L  + G      G E+++L ++ L  K   C  +LEV  K+SPG S LRG ++++        ++ K+    I++      L+ +   L+E I I         EG++   A+++L  LE  +  +  +K
Sbjct:   43 YRIGKCDPVGRYMVAKRNIYPGEVIFTDQPACVGPDNSSKPLCLGCFRKVNGSYKCPGCRWPMCCESCTRLPGHRAECTIFQKRKAVVNVP-WFDKPCSYYDAILPMRILFLKWFNPKVYHLVTLLMDHNDQLDELTIKHRQR--IIDFIRKTCRL-GKDFSEEEVNHVLGILTVNSFVVHDTEEDNLDLIGLYPWTSIMSHNCVSNTKITTREDFSYVCHATTFIREGEEIVTSYHHYHYQLYGTAYRRKDLKNTWSFECLCQRCQDPTEAGTMVSAVLCEGCKEGYLLPITPHDFESSWRCNHCFSHVPHGDVEAKVKKFEDELDTIKSSDVVSLEKLLRRMKYVLHENHYWILDVKRRLVDIWGNKP---GFEVYKLPKEILENKIDFCDHLLEVTTKLSPGPSELRGYLLWQSHNVTMRLSQWKWIRMRINTLQYIEQLKALTGKLKEVITILGPIRPDSDEGQMGQTAKMELRSLEKLIFEMSKQK 526          

Query:   45 RCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGRYMCPLCGWPMCNEICRNSPAHIP-ECRITAERGSPIKI---AVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEV--PVTMSPSQALYQNASLLEHSCVNNASKHFDM---NCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPAGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEE----LISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKL 511
            R  + K+       R++ A      G ++  E P ++ P   T PVCL CY  VDG  +C  CGWP+C+  C+    H   EC +   +G  IKI    +  ++   +Y+++  LR   MK K  ++ +    LE H  +   N    RD  T  +V+       S    +E++  + GIL+ N   V  P        +Y++ S+  +SC+ NA +          I +R  +PI++GE ++I Y D +  T  RQ+HL   K FTC+C RC DPTEL TH SS+ C G   G  V LDP      +KC+ C RV     V  ++     E    L S    + E C  F+ K+ + LHP++  ++ +K  L  M+G+ S   G  +  L    +++K+KLC E L+V + + PG+S  RG++ YEL       A+ ++S+G++     K   +   K L++ +++  +E     EG L
Sbjct:   19 RTITPKVTTGSSSARHVLAKSKWDQGVILWTEKPILVGPRYSTTPVCLGCYGTVDGSCLCQRCGWPLCDNACQYLDQHSQWECELFQSKG--IKIDGKKLKYDQTEVMYDIILPLRVWIMKTKDPDQARDFFELESHV-DTWTNTPAWRDGHT--KVLGYLNDTLSLNVSEEELSRIFGILYTNDFSVDNPSGSVKITTVYKDVSMCSNSCIPNAIRSIGSIQEGFQITLRAKVPIQEGEGVTIAYVDNMIPTPIRQEHLQYGKHFTCQCPRCSDPTELGTHGSSLNC-GQECGGEVVLDPVQDRGAFKCQKCGRVMAKDIVGKIMTKAYHETEALLASSGSETVELCEMFLTKYRRLLHPNNILMLRIKYGLSTMLGRVS---GYLMESLTPVQVIRKRKLCEESLQVLDVLDPGLSSKRGLIHYELHIAQIMIAQLEYSSGKMDVLLAKEEFESSLKSLEKALELLQFEKAESFEGTL 489          

Query:   10 CAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCS-YKICNSEXLGRYLXATRDLKPGELILMEAPTIIAP-MAVTPPVCLSCYAPVD--GRYMCPLCGWPMCNEICRNSPAHIP-ECRITAERGSPIKIAVT------INKPFPL-----YEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDIL-ALCGILFVNSHEVPVTMSPS--QALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCP--GC-PAGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACL----SFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIARLDLVELE 523
            C  C + A  RC+ C + FYC +EHQK  WK HK  C   ++I + E +GRY+ A RDL+ G++IL E P ++ P +  +  +C+ CY  +   G   C LC  P+C+  C  S +H   EC +  ++  P+    T      +++  P      ++++  LR L +K++  ++YK  + LE H   R            + R++ +F    +    + D++  +CGI   NS ++ +         LY NA+++ HSCV N    F  +  + I    PI KG+ I   Y+  +  T  R+  L   K F+C C+RC+DPTE+ +  S+  CP  GC P G ++S  P +  + W C  C+  ETP  V+ ++ +     + +++  P AC+     F+++H+  LHP H  L++ K  L   +G   +  G    +L    + +K +LC E+L     +  G++   G+  YEL     A+A  ++   + S+        E+   L E + +FSYEP     G L   AR +L   E
Sbjct:   24 CQVCAVPAALRCSACFLVFYCQQEHQKSDWKAHKKICAKPFQIKDDEIVGRYMVAARDLQAGQVILREKPCLLGPNLEESDLICVVCYRVLTPRGFLTCKLCQVPVCSVQCSQSESHREGECGVLKQK--PLGFYSTWTNRELVHRSSPSAEHANFQLIIPLRALLLKKRDVQQYKKFMALESHVSAREGTQAEVNTDERVCRLLDQFRMHEAA---NRDLVQKICGIFDTNSFDLAIQGGGRGITGLYLNAAMMMHSCVKNTRLVFSHDHVMTIYAREPIHKGDPIHHSYTRVLAPTTLRRTLLFVGKHFSCECVRCKDPTEMGSLASAWLCPNSGCGPEGVVLSETPLDLSAPWTCRHCS--ETPYSVSEILLTERRLRMEMDRLKPLACVPAWEDFLERHASLLHPQHALLVEAKQTLS--VGYGRF-QGHFYAQLTPSQVQRKVQLCREVLATLRLLESGLAAEIGLATYEL-----AFALIRWVQCQ-STPSGSEHADEIVALLMESVSVFSYEPPDSHCGILGQTARKELANWE 547          

Query:    6 SQFTCAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDG-RYMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGK----YSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPG------CPAGFLVSLDPFNYESD---WKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVK-KHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCL 506
            S   C  C   A Q C  C++  +CS +H+++H  + +  C  +KI +    GR + A+RD++P ELIL +      P   +PPVCL C  P+    + CP C WPMC++ C     H  EC   A+  + +      +     Y  +A LR L +++   + Y     L  H  ER K+ +    Y +     LR   E     + RF +E+I   CG+ + N+          QA++   S + HSCV+NA+     N ++ ++  I IKKGE ++I Y  P+  T+ R+  L +  +F C C RC DPTE  T+ +S++C         P   ++ ++    E     W C  C+   +   V  +   + +EL  +E          V+ K    LHP+HF L+ +K  +  +          +I++L  + L + Q LC ++L V NK+ PG +R RG+++  L        RK F N  IS D          + + EC+ +F     C+
Sbjct:    4 SSSACFLCGEPATQVCQDCNLVKFCSDDHRQVH--RPEKLCFPFKILHDPIKGRCMVASRDIQPLELILYDHTMAYGPKMGSPPVCLQCLKPIRNLDHPCPKCSWPMCSQKCAQGKTHELECSSLAQNTAKVDFG-NFHATHDHYRSIAPLRFLLLRDSHPKFYDQFQYLMDHNVERKKDTETWELYQKYVNDFLREDCEL----ADRFSNEEIDRACGLYWTNA--FACNSGGGQAIFPTFSFMSHSCVSNANHVVFPNKHLALQAKILIKKGEELTISYISPLQSTLRRRAKLRDKWYFECNCSRCLDPTEKGTYLASLKCGANLANSKGPCQGVMCIEELANEPSQVFWSCSKCSNRISGDSVLQLENVVAKELQDIENRRDVGLYEQVQTKFEVQLHPNHFLLVLLKRHIIAL-------GCEDIYDLELEQLKKFQALCEQVLNVLNKLDPGYNRDRGLILGHLANVKKLTCRKMFHNELISHD-------VFNRQVAECMILFGESQKCM 496          

Query:    2 AEAESQFTCAYCQIQANQRCTGCHVTFYCSREHQKLHWKKHKNRCCS-----YKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCY---APVDGRYMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSR-DKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPAGFLVSLDPFNYESDW 343
            ++ + Q  C  C   A   C+ C   FYC+REHQK HWK HK  C +     Y++  +  LGR+L AT D+  G   L E+P ++ P  ++ PVCL C+     ++    C  C WP+C+  C +S  H PECR+    GS + +  +  +   +Y  + +LR L +++ +   +K   + E H  +R++   Y++ +K  ++  I  F  +   ++ D +IL  CG L  N  E+       +A+Y+ A ++ H C  N    FD + +I +     I+KG  IS  Y+  IW T+NR+ HL  +K F C+C RC+DPTE  T+ S+  C  C  G ++   P +  + W
Sbjct:  220 SDGKPQGDCEICGHLAKMFCSCCKHVFYCTREHQKKHWKSHKEDCSALKKLPYRVERNGELGRHLVATTDIPAGTHFLNESPMVMGPRQMSKPVCLGCHKELVDLESVVKCSRCLWPLCSRKCEDSKLHEPECRVIKYGGSKVNVE-SFGQVNMMYACITVLRALALQDGAQTIWKDYTKFESHLDKRMETEIYTKVNKEKVVYFIHYFLKL-INKYSDLEILETCGRLDTNCFEIKQNGMNLRAMYRVACIISHDCCPNTKHTFDPDHSINLFATTNIRKGSIISATYTQSIWNTMNRRAHLYMSKCFWCQCRRCRDPTEFGTYLSANSCNAC-GGQVIPTQPLDNSAKW 567          

Query:   61 LXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAP---VDGRYMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPL-------------------------YEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGKYSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSP-SQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPAGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSF-----VKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQE 487
            L A+RD+K  E++L E P +I P   +P  CL C+ P   V   + CP C +P+C E C  S  +  +       G  +KI                                   Y ++ +LR L +KE+  E +  +++L  H  E  + G  + + + M  VI      P     +++ L   GI   N+  + +T      +LY   + + H C+ N       +  + +R + PI+KG+ IS  Y  P+  T  R+  L    +F C+C RC DPTEL ++ S+  C  C +G +++ DP + ES W C  C+   T  ++ A +  I   L S++    +  L       + K S  LHP H    D+   L  + G   YG   ++       L +K + C ++L+   ++ PG S  R  ++ EL       A++    G I  D M+ IL E
Sbjct:    1 LVASRDVKTMEILLEENPCVIGPYVKSPVQCLECFKPIPDVSQAFRCPGCQFPLCGEECSQSKLNHAQDECDQLSGGNLKIQKIPGDNGEKPKKRSKGKKHQETHSMAGSSACNFDYSIITVLRSLRLKERKPEVWNNIMQLVDHNHEMAQEGSPTWN-LWMTEVIPRLKQFPGIN--EQEALRFLGIGVTNNANLNLTHGGRGTSLYPTFARINHQCICNTKVIKQKDHKLQVRASGPIEKGQEISNQYVKPLNNTAIRRSILRSKWYFECKCPRCSDPTELGSYLSAFICSKCKSGTVLAQDPLDPESLWICRDCSTSFTVDYLQARLNEI---LASIDSAHLQTNLIHRYEECLHKFSHTLHPGHQIFTDLNSQLAILYGNPMYG---DLSSWSRPSLDRKIQACQQVLDTNGRVDPGFSAWREKILIELTRTKVHLAQRDLRAGVIGEDKMEEILGE 452          

Query:   28 FYCSREHQKLHWKKHKNRCCSYKICNSEXLGRYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGRYMCPLCGWPMCNEICRNSPAHIPECRITAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGK-YSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPVTMSPS-QALYQNASLLEHSCVNNASKHFDMNC--NILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGC-PAGFLVSLDPFNYESDWKC--ETCNRVETPRFVNAVIRSIGEELISLEKGSPEACLSFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDHMKNILQEVKKYLQECIQIFSYEPTCLQEGKLAAIAR 516
            ++C   H   H +K    C   K+ + + +GR   ATRD+K GE+I  E P ++ P  VT P CL C                                    ++  P K  +        YE++  LR +   +       A   L  H  E+  N + +  ++ +M   +    S+    F  +D++   G++ VN+ E+   +    + ++   SL+ HSC  NA      +   + +   ++ I +GE I+I Y   I  +  R+  L E  +F CRC RC DPTEL T+   I C  C P+GFL+  D  +Y S W C    C    +    +  +  +  E   L++      L+F+++  + LH +H+ L  ++  +  +     Y   S    + E+ L  K  L T  L V N I PG++R RG  +YEL     A    +  +G +        L+E  +  QE  Q   ++     EG   A  R
Sbjct:  459 WFCRPGHGNYH-RKLDGSCSPMKVASQKDVGRCTFATRDIKAGEVIFNENPIVVGPNNVTTPQCLVC-----------------------------------TKKLVPKKSDLN-------YELILPLRLITHSDPDVRSLMAT--LMDHRVEKEANAQVWEHNRQSM---VDPLTSILEGHFTSDDVIRAVGVVEVNNFEIYNPLDCGFRGIFPLTSLMSHSCTPNARHAIGRSAPWSSVCIASVDIPRGEEITITYVPLILCSSERRAKLKENWYFDCRCRRCLDPTELGTNLGGILCQACSPSGFLLPADSIDYNSKWICSRSDCQAELSAEECSQKVERLLTEKDHLDRKDIPGFLTFLQRAGEELHVNHYVLNSLRRWIVSL-----YCKSSTCSTITEEMLRSKVHLATLYLSVLNTIEPGLTRNRGRALYELAEAQLAILSLQLKSGSLDGTDFLGTLEECLERAQEAAQCLEHD----TEGSFEAYIR 897          

Query:   59 RYLXATRDLKPGELILMEAPTIIAPMAVTPPVCLSCYAPVDGRYMCPLCGWPMCNEICRNSPAHIP-ECRI---TAERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPHTKERIKNGK--YSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPV---TMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRVAIPIKKGEHISIMYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPAGFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSI 364
            R++ ATRD++  E+IL E P +I P       CL C+  V   Y C  C  P+C+  C++   H   EC+        G   +   T+    P    V  LR L  + +  + +  +  L  H      NGK   +   + ++ +IR+      T F   +I  + GIL  N  ++       +P  ALY   SL+ H+C NN +     + ++ +R  + I KG+ I   Y     G V R++ +    FF C+C RC DPTE  T  S++RC  C +G+L+  D  + ESDWKC+ C  +   + VN VI ++
Sbjct:  171 RFMVATRDIEALEMILWEQPAVIGPYTREAQGCLQCFQKVSSPYTCQRCNLPVCDAKCQDGTLHKDNECQFFQAGVTEGGQARGTGTV----PSQICVTPLRMLLKRARDPKVFAQIDMLMDHAT----NGKDLLTLSTLKVICMIRD--QRQGTNFAQSEIQRMIGILRTNGMKLEQRGEDGTPGVALYPIYSLINHACSNNTNYVKYSDRHMELRSQVAIGKGQEIFTRYISSTLGNVRRREEIERNWFFRCQCPRCLDPTEFGTFMSAVRCFQCQSGYLLPSDAQDLESDWKCDRCEWIILHQKVNEVITTL 475          

Query:   57 LGRYLXATRDLKPGELILMEAPTIIAPMAVTP---PVCLSCYAPVDGRYMCPLCGWPMCNEICRNSPAHIPECRITA--ERGSPIKIAVTINKPFPLYEVVALLRCLYMKEKSSEKYKALIRLEPH--TKERIKNGK---YSRDKMTMLRVIREFFSVPSTRFPDEDILALCGILFVNSHEVPV---TMSPSQALYQNASLLEHSCVNNASKHFDMNCNILIRV--AIPIKKGEHISI--MYSDPIWGTVNRQQHLLETKFFTCRCIRCQDPTELNTHFSSIRCPGCPA------GFLVSLDPFNYESDWKCETCNRVETPRFVNAVIRSIGEELISLEKGSPEACL-SFVKKHSQNLHPHHFYLMDVKLALCQMIGQSSYGTGSEIFELHEKDLLQKQKLCTEILEVANKISPGVSRLRGVVMYELQAXXAAYARKKFSNGEISSDH 480
            + ++L A RD+ PG+ I  E P    P    P    +C+ C + +D   +C  C WP+C+  C  S  H  EC   A   R S   +        PL  +V ++RCL MK +    ++ L+ LE H   +  I+N +      D++ +   IRE  S       D DI+A      V S  + V   ++ P  A+Y    LL  +CV N    FD + + L+ V  A  I KGE I+   +      GT  R++ L+  +   C C RC DP E  +  S+  C  C        G ++ ++P   ES W+C+ CN   T   V +++  + + L + +    E     F+  +   LHP+H+ ++  K  L  +         S   ++   D L+  ++  ++L+VA+ + PG++  RG +++ L         ++  N   S +H
Sbjct:   20 VAKHLVAIRDIPPGKAIFSETPLAQGPSPDHPNDDDICIVCLSELDHAMVCSKCFWPVCSSECGRSDQHKMECATLAACARESEEDL-------LPLRHLV-VMRCLLMKHRDQYAWEKLMDLEDHHGVQTLIRNVEEELSDMDRLELKYFIRE--SCGMGIKTDLDIVA----DIVQSSSIQVDCESLEPFPAMYLTGGLLSQACVPNTVLRFDEDKDFLMTVYSARKISKGEKITFCPLQHLTKSGTRERRKKLMR-RLINCFCDRCVDPEECGSFSSAFICQKCAPKGTEDRGLILPINPVEEESPWQCQKCNYSMTSDTVESLLSRLRDSLEATKCEDNEVKFRDFILSNRSILHPNHYLMIACKDGLFNL----KTSEASRAIDISIADKLETVEMGLDLLKVADILEPGLTSTRGKLLFTLGTTLQEMLSQEVMNRMESPEH 448