EMLSAG00000003515, EMLSAG00000003515-686281 (gene) Lepeophtheirus salmonis

Overview
NameEMLSAG00000003515
Unique NameEMLSAG00000003515-686281
Typegene
OrganismLepeophtheirus salmonis (salmon louse)
Associated RNAi Experiments

Nothing found

Homology
BLAST of EMLSAG00000003515 vs. GO
Match: - (symbol:WHSC1L1 "Uncharacterized protein" species:9031 "Gallus gallus" [GO:0005634 "nucleus" evidence=IEA] [GO:0008270 "zinc ion binding" evidence=IEA] [GO:0018024 "histone-lysine N-methyltransferase activity" evidence=IEA] InterPro:IPR001841 Pfam:PF00856 InterPro:IPR001214 InterPro:IPR001965 InterPro:IPR006560 InterPro:IPR019787 Pfam:PF00628 PROSITE:PS50016 PROSITE:PS50280 PROSITE:PS51215 SMART:SM00184 SMART:SM00249 SMART:SM00317 SMART:SM00570 Pfam:PF00855 GO:GO:0005634 GO:GO:0008270 Gene3D:3.30.40.10 InterPro:IPR011011 InterPro:IPR013083 SUPFAM:SSF57903 InterPro:IPR019786 PROSITE:PS01359 GO:GO:0018024 GO:GO:0018022 InterPro:IPR003616 SMART:SM00508 PROSITE:PS50868 GeneTree:ENSGT00740000114921 InterPro:IPR000313 PROSITE:PS50812 SMART:SM00293 OrthoDB:EOG7Z69BG TreeFam:TF329088 CTD:54904 KO:K11425 OMA:MEKDIHK EMBL:AADN03008079 RefSeq:XP_001232891.1 UniGene:Gga.29652 UniGene:Gga.53440 Ensembl:ENSGALT00000005228 GeneID:426778 KEGG:gga:426778 NextBio:20828194 PRO:PR:E1C6X8 Uniprot:E1C6X8)

HSP 1 Score: 65.4698 bits (158), Expect = 1.768e-9
Identity = 47/175 (26.86%), Postives = 86/175 (49.14%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKFPKRKKDFEPGKKFRN---IFERA-----VKEAEAXMCIPVALRLEKLGFVYIPTNIDGATRNVLAKKKKSRRRSSKTSESENISSKFPLYQTVSRNDHQNI 241
            G L+W+K+  + +WP + + DP   V +K+     R + H+ F +    RAWV+E  V  Y+G++++++L  +  K+  +    +K R      ERA     +  AE  + +    R+E+  F+Y    ID     VL+K KK     +  S+SE   ++ P     ++ +H N+
Sbjct:  271 GDLVWSKVGTYPWWPCMVSCDPQLDVHTKINTRGAR-EYHVQFFSNQPERAWVHEKRVREYKGHKQYEQLLAEAAKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERIEQYTFIY----IDKEPEEVLSKAKK-----TTASKSETKKNRRPKPALNTQTEHANV 435          
BLAST of EMLSAG00000003515 vs. GO
Match: - (symbol:Whsc1l1 "Wolf-Hirschhorn syndrome candidate 1-like 1 (human)" species:10090 "Mus musculus" [GO:0005634 "nucleus" evidence=IEA] [GO:0005694 "chromosome" evidence=IEA] [GO:0006351 "transcription, DNA-templated" evidence=IEA] [GO:0006355 "regulation of transcription, DNA-templated" evidence=IEA] [GO:0008168 "methyltransferase activity" evidence=IEA] [GO:0008270 "zinc ion binding" evidence=IEA] [GO:0016568 "chromatin modification" evidence=IEA] [GO:0016571 "histone methylation" evidence=ISO] [GO:0016740 "transferase activity" evidence=IEA] [GO:0018022 "peptidyl-lysine methylation" evidence=ISO] [GO:0018024 "histone-lysine N-methyltransferase activity" evidence=ISO] [GO:0032259 "methylation" evidence=IEA] [GO:0034968 "histone lysine methylation" evidence=ISO] [GO:0046872 "metal ion binding" evidence=IEA] Pfam:PF00856 InterPro:IPR001214 InterPro:IPR001965 InterPro:IPR006560 InterPro:IPR019787 PROSITE:PS50016 PROSITE:PS50280 PROSITE:PS51215 SMART:SM00249 SMART:SM00317 SMART:SM00570 MGI:MGI:2142581 Pfam:PF00855 GO:GO:0005634 GO:GO:0005694 GO:GO:0006355 GO:GO:0008270 GO:GO:0006351 Gene3D:3.30.40.10 InterPro:IPR011011 InterPro:IPR013083 SUPFAM:SSF57903 InterPro:IPR019786 PROSITE:PS01359 eggNOG:COG2940 GO:GO:0018024 GO:GO:0034968 GO:GO:0018022 InterPro:IPR003616 SMART:SM00508 PROSITE:PS50868 GeneTree:ENSGT00740000114921 InterPro:IPR000313 PROSITE:PS50812 SMART:SM00293 EMBL:AC156990 OrthoDB:EOG7Z69BG HOGENOM:HOG000230893 HOVERGEN:HBG079979 CTD:54904 KO:K11425 ChiTaRS:WHSC1L1 EMBL:AK079952 EMBL:AK132725 EMBL:AK156746 EMBL:AK170040 EMBL:AC162367 EMBL:BC064447 RefSeq:NP_001001735.1 RefSeq:XP_006509168.1 UniGene:Mm.217337 ProteinModelPortal:Q6P2L6 SMR:Q6P2L6 BioGrid:231497 IntAct:Q6P2L6 MINT:MINT-4110979 PhosphoSite:Q6P2L6 PaxDb:Q6P2L6 PRIDE:Q6P2L6 DNASU:234135 Ensembl:ENSMUST00000146919 Ensembl:ENSMUST00000155861 GeneID:234135 KEGG:mmu:234135 UCSC:uc009lgk.1 UCSC:uc009lgm.1 UCSC:uc009lgp.1 InParanoid:Q6P2L6 NextBio:382034 PRO:PR:Q6P2L6 ArrayExpress:Q6P2L6 Bgee:Q6P2L6 Genevestigator:Q6P2L6 Uniprot:Q6P2L6)

HSP 1 Score: 65.0846 bits (157), Expect = 2.227e-9
Identity = 49/166 (29.52%), Postives = 83/166 (50.00%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKFPKRKKDFEPGKKFRN---IFERA-----VKEAEAXMCIPVALRLEKLGFVYIPTNIDGAT----RNVLAK---KKKSRRRSSKTSESENISS 225
            G L+W+K+  + +WP + + DP   V SK+     R + H+ F +    RAWV+E  V  Y+G+E+++EL  +  K+  +    +K R      ERA     +  AE  + +    R+E+  F+YI    + A+    +NV +K   KK  R RS   S+ E  ++
Sbjct:  271 GDLVWSKVGTYPWWPCMVSSDPQLEVHSKINTRGAR-EYHVQFFSNQPERAWVHEKRVREYKGHEQYEELLAEAAKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERVEQYTFIYIDKQPEEASSQAKKNVTSKTEVKKPRRPRSVLNSQPEQTNA 435          
BLAST of EMLSAG00000003515 vs. GO
Match: - (symbol:Whsc1l1 "Wolf-Hirschhorn syndrome candidate 1-like 1" species:10116 "Rattus norvegicus" [GO:0003674 "molecular_function" evidence=ND] [GO:0005575 "cellular_component" evidence=ND] [GO:0005634 "nucleus" evidence=IEA] [GO:0008150 "biological_process" evidence=ND] [GO:0008270 "zinc ion binding" evidence=IEA] [GO:0016571 "histone methylation" evidence=ISO] [GO:0018024 "histone-lysine N-methyltransferase activity" evidence=IEA;ISO] [GO:0034968 "histone lysine methylation" evidence=ISO] InterPro:IPR001841 Pfam:PF00856 InterPro:IPR001214 InterPro:IPR001965 InterPro:IPR006560 InterPro:IPR019787 PROSITE:PS50016 PROSITE:PS50280 PROSITE:PS51215 SMART:SM00184 SMART:SM00249 SMART:SM00317 SMART:SM00570 Pfam:PF00855 RGD:1308980 GO:GO:0005634 GO:GO:0008270 Gene3D:3.30.40.10 InterPro:IPR011011 InterPro:IPR013083 SUPFAM:SSF57903 InterPro:IPR019786 PROSITE:PS01359 EMBL:CH473970 GO:GO:0018024 GO:GO:0018022 InterPro:IPR003616 SMART:SM00508 PROSITE:PS50868 GeneTree:ENSGT00740000114921 InterPro:IPR000313 PROSITE:PS50812 SMART:SM00293 OrthoDB:EOG7Z69BG CTD:54904 KO:K11425 OMA:MEKDIHK EMBL:AABR06089034 EMBL:AABR06089035 EMBL:AABR06089036 EMBL:AABR06089037 RefSeq:NP_001099560.1 UniGene:Rn.163332 Ensembl:ENSRNOT00000066974 GeneID:290831 KEGG:rno:290831 NextBio:631733 Uniprot:D3ZK47)

HSP 1 Score: 63.5438 bits (153), Expect = 5.948e-9
Identity = 46/166 (27.71%), Postives = 79/166 (47.59%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKFPKRKKDFEPGKKFRN---IFERA-----VKEAEAXMCIPVALRLEKLGFVYI-------PTNIDGATRNVLAKKKKSRRRSSKTSESENISS 225
            G L+W+K+  + +WP + + DP   V +K+     R + H+ F +    RAWV+E  V  Y+G+E+++EL  +  K+  +    +K R      ERA     +  AE  + +    R+E+  F+YI       P+    +  +    KK  R RS   S+ E  S+
Sbjct:  272 GDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAR-EYHVQFFSNQPERAWVHEKRVREYKGHEQYEELLAEAAKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALQMTREERVEQYTFIYIDKQPEESPSQAKKSVTSKAEVKKPRRPRSVGNSQPEQTSA 436          
BLAST of EMLSAG00000003515 vs. GO
Match: - (symbol:WHSC1L1 "Uncharacterized protein" species:9913 "Bos taurus" [GO:0005634 "nucleus" evidence=IEA] [GO:0008270 "zinc ion binding" evidence=IEA] [GO:0018024 "histone-lysine N-methyltransferase activity" evidence=IEA] InterPro:IPR001841 Pfam:PF00856 InterPro:IPR001214 InterPro:IPR001965 InterPro:IPR006560 InterPro:IPR019787 PROSITE:PS50016 PROSITE:PS50280 PROSITE:PS51215 SMART:SM00184 SMART:SM00249 SMART:SM00317 SMART:SM00570 Pfam:PF00855 GO:GO:0005634 GO:GO:0008270 Gene3D:3.30.40.10 InterPro:IPR011011 InterPro:IPR013083 SUPFAM:SSF57903 InterPro:IPR019786 PROSITE:PS01359 GO:GO:0018024 GO:GO:0018022 InterPro:IPR003616 SMART:SM00508 PROSITE:PS50868 GeneTree:ENSGT00740000114921 InterPro:IPR000313 PROSITE:PS50812 SMART:SM00293 OrthoDB:EOG7Z69BG TreeFam:TF329088 OMA:MEKDIHK EMBL:DAAA02060851 EMBL:DAAA02060847 EMBL:DAAA02060848 EMBL:DAAA02060849 EMBL:DAAA02060850 Ensembl:ENSBTAT00000061245 ArrayExpress:E1BNH7 Uniprot:E1BNH7)

HSP 1 Score: 62.3882 bits (150), Expect = 1.478e-8
Identity = 43/152 (28.29%), Postives = 77/152 (50.66%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKFPKRKKDFEPGKKFRN---IFERA-----VKEAEAXMCIPVALRLEKLGFVYI----PTNIDGATRNVLAKK--KKSRR 212
            G L+W+K+  + +WP + + DP   V +K+     R + H+ F +    RAWV+E  V  Y+G+++++EL  +  ++  +    +K R      ERA     +  AE  + +    R+E+  F+YI       +  A +NV++K   KK RR
Sbjct:  272 GDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAR-EYHVQFFSNQPERAWVHEKRVREYKGHKQYEELLAEATRQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALTMTREERIEQYTFIYIDKQPEETLSQAKKNVVSKAEVKKPRR 422          
BLAST of EMLSAG00000003515 vs. GO
Match: - (symbol:MSH6 "DNA mismatch repair protein Msh6" species:9606 "Homo sapiens" [GO:0000228 "nuclear chromosome" evidence=IBA] [GO:0000710 "meiotic mismatch repair" evidence=ISS;IBA] [GO:0000790 "nuclear chromatin" evidence=IEA] [GO:0003682 "chromatin binding" evidence=IEA] [GO:0005515 "protein binding" evidence=IPI] [GO:0005634 "nucleus" evidence=IDA] [GO:0005737 "cytoplasm" evidence=IDA] [GO:0005794 "Golgi apparatus" evidence=IDA] [GO:0005886 "plasma membrane" evidence=IDA] [GO:0006200 "ATP catabolic process" evidence=IDA;IBA] [GO:0006281 "DNA repair" evidence=IDA] [GO:0006298 "mismatch repair" evidence=IGI;IMP;IDA] [GO:0007131 "reciprocal meiotic recombination" evidence=IBA] [GO:0008094 "DNA-dependent ATPase activity" evidence=IBA] [GO:0008340 "determination of adult lifespan" evidence=ISS] [GO:0008630 "intrinsic apoptotic signaling pathway in response to DNA damage" evidence=ISS;IBA] [GO:0009411 "response to UV" evidence=ISS;IBA] [GO:0016446 "somatic hypermutation of immunoglobulin genes" evidence=ISS;IBA] [GO:0016447 "somatic recombination of immunoglobulin gene segments" evidence=ISS] [GO:0030983 "mismatched DNA binding" evidence=IDA] [GO:0032301 "MutSalpha complex" evidence=IDA] [GO:0035064 "methylated histone residue binding" evidence=IDA] [GO:0043231 "intracellular membrane-bounded organelle" evidence=IDA] [GO:0045190 "isotype switching" evidence=ISS;IBA] [GO:0045910 "negative regulation of DNA recombination" evidence=IDA] [GO:0051096 "positive regulation of helicase activity" evidence=IDA] [GO:0097193 "intrinsic apoptotic signaling pathway" evidence=ISS] [GO:0005730 "nucleolus" evidence=IDA] [GO:0042803 "protein homodimerization activity" evidence=IPI] [GO:0043570 "maintenance of DNA repeat elements" evidence=IMP] [GO:0000287 "magnesium ion binding" evidence=IDA] [GO:0000400 "four-way junction DNA binding" evidence=IDA] [GO:0003690 "double-stranded DNA binding" evidence=IDA] [GO:0005524 "ATP binding" evidence=IDA] [GO:0016887 "ATPase activity" evidence=IDA] [GO:0032137 "guanine/thymine mispair binding" evidence=IDA] [GO:0032142 "single guanine insertion binding" evidence=IDA] [GO:0032143 "single thymine insertion binding" evidence=IDA] [GO:0032357 "oxidized purine DNA binding" evidence=IDA] [GO:0032405 "MutLalpha complex binding" evidence=IDA] [GO:0043531 "ADP binding" evidence=IDA] InterPro:IPR000432 InterPro:IPR007695 InterPro:IPR007696 InterPro:IPR007860 InterPro:IPR007861 InterPro:IPR015536 InterPro:IPR016151 Pfam:PF00488 Pfam:PF01624 Pfam:PF05188 Pfam:PF05190 Pfam:PF05192 PROSITE:PS00486 SMART:SM00533 SMART:SM00534 Pfam:PF00855 InterPro:IPR027417 SUPFAM:SSF52540 GO:GO:0005524 GO:GO:0008340 GO:GO:0009411 GO:GO:0008630 GO:GO:0003684 GO:GO:0003682 GO:GO:0000790 GO:GO:0016446 GO:GO:0045190 GO:GO:0035064 MIM:276300 GO:GO:0030983 GO:GO:0007131 GO:GO:0000228 InterPro:IPR000313 PROSITE:PS50812 GO:GO:0045910 Orphanet:144 SMART:SM00293 MIM:608089 GO:GO:0008094 GO:GO:0051096 eggNOG:COG0249 SUPFAM:SSF48334 Orphanet:252202 Orphanet:587 Orphanet:99817 GO:GO:0032137 GO:GO:0000710 GO:GO:0032301 Gene3D:3.40.1170.10 SUPFAM:SSF55271 PDB:2O8B PDB:2O8C PDB:2O8D PDB:2O8E PDB:2O8F PDBsum:2O8B PDBsum:2O8C PDBsum:2O8D PDBsum:2O8E PDBsum:2O8F HOGENOM:HOG000243127 KO:K08737 InterPro:IPR017261 PANTHER:PTHR11361:SF31 PIRSF:PIRSF037677 OMA:HMDAVIG CTD:2956 OrthoDB:EOG7K9K27 EMBL:U73737 EMBL:U73732 EMBL:U73733 EMBL:U73734 EMBL:U73736 EMBL:D89645 EMBL:D89646 EMBL:AY082894 EMBL:BC004246 EMBL:U54777 EMBL:U28946 PIR:JC5839 RefSeq:NP_000170.1 UniGene:Hs.445052 PDB:2GFU PDBsum:2GFU ProteinModelPortal:P52701 SMR:P52701 BioGrid:109211 DIP:DIP-32972N IntAct:P52701 MINT:MINT-131993 STRING:9606.ENSP00000234420 PhosphoSite:P52701 DMDM:68067672 PaxDb:P52701 PeptideAtlas:P52701 PRIDE:P52701 DNASU:2956 Ensembl:ENST00000234420 GeneID:2956 KEGG:hsa:2956 UCSC:uc002rwc.2 UCSC:uc002rwd.4 GeneCards:GC02P047924 HGNC:HGNC:7329 HPA:CAB009091 HPA:HPA028376 HPA:HPA028446 MIM:600678 MIM:614350 neXtProt:NX_P52701 PharmGKB:PA184 HOVERGEN:HBG000101 InParanoid:P52701 PhylomeDB:P52701 TreeFam:TF105842 EvolutionaryTrace:P52701 GeneWiki:MSH6 GenomeRNAi:2956 NextBio:11716 PMAP-CutDB:P52701 PRO:PR:P52701 ArrayExpress:P52701 Bgee:P52701 CleanEx:HS_MSH6 Genevestigator:P52701 Uniprot:P52701)

HSP 1 Score: 62.003 bits (149), Expect = 1.869e-8
Identity = 25/55 (45.45%), Postives = 34/55 (61.82%), Query Frame = 0
Query:  296 GTLIWGHMAGFPYWPCFV-TRSSDGDYIREAKNKISVHVQFFNWNDESGWVTKTM 349
            G L+W  M G+P+WPC V     DG +IRE    + VHVQFF+ +   GWV+K +
Sbjct:   93 GDLVWAKMEGYPWWPCLVYNHPFDGTFIREKGKSVRVHVQFFDDSPTRGWVSKRL 147          
BLAST of EMLSAG00000003515 vs. GO
Match: - (symbol:Msh6 "mutS homolog 6 (E. coli)" species:10090 "Mus musculus" [GO:0000166 "nucleotide binding" evidence=IEA] [GO:0000287 "magnesium ion binding" evidence=ISO] [GO:0000400 "four-way junction DNA binding" evidence=ISO;IBA] [GO:0000710 "meiotic mismatch repair" evidence=IBA] [GO:0000790 "nuclear chromatin" evidence=IDA] [GO:0003677 "DNA binding" evidence=IGI;IMP] [GO:0003682 "chromatin binding" evidence=IDA] [GO:0003684 "damaged DNA binding" evidence=IGI;IMP] [GO:0003690 "double-stranded DNA binding" evidence=ISO] [GO:0005524 "ATP binding" evidence=ISO] [GO:0005622 "intracellular" evidence=IMP] [GO:0005634 "nucleus" evidence=ISO] [GO:0005694 "chromosome" evidence=IEA] [GO:0005737 "cytoplasm" evidence=ISO] [GO:0005794 "Golgi apparatus" evidence=ISO] [GO:0005886 "plasma membrane" evidence=ISO] [GO:0006200 "ATP catabolic process" evidence=ISO;IBA] [GO:0006281 "DNA repair" evidence=ISO] [GO:0006298 "mismatch repair" evidence=ISO;IGI;IMP] [GO:0006974 "cellular response to DNA damage stimulus" evidence=IEA] [GO:0007131 "reciprocal meiotic recombination" evidence=IBA] [GO:0008094 "DNA-dependent ATPase activity" evidence=IBA] [GO:0008340 "determination of adult lifespan" evidence=IMP] [GO:0008630 "intrinsic apoptotic signaling pathway in response to DNA damage" evidence=IMP] [GO:0009411 "response to UV" evidence=IMP] [GO:0016446 "somatic hypermutation of immunoglobulin genes" evidence=IMP] [GO:0016447 "somatic recombination of immunoglobulin gene segments" evidence=IMP] [GO:0016887 "ATPase activity" evidence=ISO] [GO:0030983 "mismatched DNA binding" evidence=ISO] [GO:0032137 "guanine/thymine mispair binding" evidence=ISO;IDA] [GO:0032138 "single base insertion or deletion binding" evidence=IBA] [GO:0032142 "single guanine insertion binding" evidence=ISO] [GO:0032143 "single thymine insertion binding" evidence=ISO] [GO:0032301 "MutSalpha complex" evidence=ISO;IDA] [GO:0032357 "oxidized purine DNA binding" evidence=ISO] [GO:0032405 "MutLalpha complex binding" evidence=ISO] [GO:0035064 "methylated histone residue binding" evidence=ISO] [GO:0043231 "intracellular membrane-bounded organelle" evidence=ISO] [GO:0043531 "ADP binding" evidence=ISO] [GO:0043570 "maintenance of DNA repeat elements" evidence=IBA] [GO:0045190 "isotype switching" evidence=IMP] [GO:0045910 "negative regulation of DNA recombination" evidence=ISO;IMP] [GO:0051096 "positive regulation of helicase activity" evidence=ISO] [GO:0097193 "intrinsic apoptotic signaling pathway" evidence=IMP] InterPro:IPR000432 InterPro:IPR007695 InterPro:IPR007696 InterPro:IPR007860 InterPro:IPR007861 InterPro:IPR015536 InterPro:IPR016151 Pfam:PF00488 Pfam:PF01624 Pfam:PF05188 Pfam:PF05190 Pfam:PF05192 PROSITE:PS00486 SMART:SM00533 SMART:SM00534 MGI:MGI:1343961 Pfam:PF00855 InterPro:IPR027417 SUPFAM:SSF52540 GO:GO:0005524 GO:GO:0008340 GO:GO:0009411 GO:GO:0008630 GO:GO:0000287 GO:GO:0003684 GO:GO:0043531 GO:GO:0003682 GO:GO:0000790 GO:GO:0016446 GO:GO:0045190 GO:GO:0035064 GO:GO:0007131 InterPro:IPR000313 PROSITE:PS50812 GO:GO:0043570 GO:GO:0045910 SMART:SM00293 GO:GO:0008094 GO:GO:0051096 eggNOG:COG0249 SUPFAM:SSF48334 GO:GO:0000400 GO:GO:0032137 GO:GO:0000710 GO:GO:0032301 GO:GO:0032138 Gene3D:3.40.1170.10 SUPFAM:SSF55271 GO:GO:0032357 GO:GO:0032142 GO:GO:0032143 HOGENOM:HOG000243127 KO:K08737 InterPro:IPR017261 PANTHER:PTHR11361:SF31 PIRSF:PIRSF037677 OMA:HMDAVIG CTD:2956 GeneTree:ENSGT00550000075024 OrthoDB:EOG7K9K27 HOVERGEN:HBG000101 TreeFam:TF105842 EMBL:U42190 EMBL:AF031087 EMBL:AF031085 EMBL:AF031086 EMBL:BC051160 EMBL:BC051634 EMBL:U61388 EMBL:U61389 RefSeq:NP_034960.1 UniGene:Mm.18210 ProteinModelPortal:P54276 SMR:P54276 BioGrid:201528 IntAct:P54276 PhosphoSite:P54276 PaxDb:P54276 PRIDE:P54276 Ensembl:ENSMUST00000005503 GeneID:17688 KEGG:mmu:17688 UCSC:uc008dvd.2 InParanoid:Q6GTK8 ChiTaRS:MSH6 NextBio:292264 PRO:PR:P54276 ArrayExpress:P54276 Bgee:P54276 CleanEx:MM_MSH6 Genevestigator:P54276 Uniprot:P54276)

HSP 1 Score: 61.2326 bits (147), Expect = 2.837e-8
Identity = 25/55 (45.45%), Postives = 34/55 (61.82%), Query Frame = 0
Query:  296 GTLIWGHMAGFPYWPCFV-TRSSDGDYIREAKNKISVHVQFFNWNDESGWVTKTM 349
            G L+W  M G+P+WPC V     DG +IR+    + VHVQFF+ +   GWV+K M
Sbjct:   93 GDLVWAKMEGYPWWPCLVYNHPFDGTFIRKKGKSVRVHVQFFDDSPTRGWVSKRM 147          
BLAST of EMLSAG00000003515 vs. GO
Match: - (symbol:WHSC1L1 "WHSC1L1 protein" species:9606 "Homo sapiens" [GO:0005634 "nucleus" evidence=IEA] [GO:0008270 "zinc ion binding" evidence=IEA] [GO:0018024 "histone-lysine N-methyltransferase activity" evidence=IEA] InterPro:IPR001841 Pfam:PF00856 InterPro:IPR001214 InterPro:IPR001965 InterPro:IPR006560 InterPro:IPR019787 PROSITE:PS50016 PROSITE:PS50280 PROSITE:PS51215 SMART:SM00184 SMART:SM00249 SMART:SM00317 SMART:SM00570 Pfam:PF00855 GO:GO:0005634 GO:GO:0008270 Gene3D:3.30.40.10 InterPro:IPR011011 InterPro:IPR013083 SUPFAM:SSF57903 InterPro:IPR019786 PROSITE:PS01359 GO:GO:0018024 GO:GO:0034968 GO:GO:0018022 InterPro:IPR003616 SMART:SM00508 PROSITE:PS50868 InterPro:IPR000313 PROSITE:PS50812 SMART:SM00293 EMBL:AC087362 UniGene:Hs.434966 EMBL:AC087623 HOVERGEN:HBG079979 UniGene:Hs.608111 UniGene:Hs.655314 GeneID:54904 KEGG:hsa:54904 CTD:54904 HGNC:HGNC:12767 KO:K11425 ChiTaRS:WHSC1L1 EMBL:BC143510 RefSeq:XP_005273604.1 Ensembl:ENST00000527502 UCSC:uc011lbm.2 NextBio:35481221 Uniprot:B7ZL11)

HSP 1 Score: 60.8474 bits (146), Expect = 3.733e-8
Identity = 41/144 (28.47%), Postives = 72/144 (50.00%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKFPKRKKDFEPGKKFRN---IFERA-----VKEAEAXMCIPVALRLEKLGFVYIPTNIDGATRNVLAKKKKS 210
            G L+W+K+  + +WP + + DP   V +K+     R + H+ F +    RAWV+E  V  Y+G+++++EL  +  K+  +    +K R      ERA     +  AE  + +    R+E+  F+Y    ID      L++ KKS
Sbjct:  271 GDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAR-EYHVQFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERIEQYTFIY----IDKQPEEALSQAKKS 409          
BLAST of EMLSAG00000003515 vs. GO
Match: - (symbol:WHSC1L1 "Histone-lysine N-methyltransferase NSD3" species:9606 "Homo sapiens" [GO:0005515 "protein binding" evidence=IPI] [GO:0005634 "nucleus" evidence=IC] [GO:0005694 "chromosome" evidence=IEA] [GO:0006351 "transcription, DNA-templated" evidence=IEA] [GO:0006355 "regulation of transcription, DNA-templated" evidence=IEA] [GO:0008270 "zinc ion binding" evidence=IEA] [GO:0016571 "histone methylation" evidence=IDA] [GO:0018024 "histone-lysine N-methyltransferase activity" evidence=IDA] [GO:0034968 "histone lysine methylation" evidence=IDA] InterPro:IPR001841 Pfam:PF00856 InterPro:IPR001214 InterPro:IPR001965 InterPro:IPR006560 InterPro:IPR019787 PROSITE:PS50016 PROSITE:PS50280 PROSITE:PS51215 SMART:SM00184 SMART:SM00249 SMART:SM00317 SMART:SM00570 Pfam:PF00855 GO:GO:0005634 GO:GO:0005694 GO:GO:0006355 EMBL:CH471080 GO:GO:0008270 GO:GO:0006351 Gene3D:3.30.40.10 InterPro:IPR011011 InterPro:IPR013083 SUPFAM:SSF57903 InterPro:IPR019786 PROSITE:PS01359 eggNOG:COG2940 GO:GO:0018024 InterPro:IPR003616 SMART:SM00508 PROSITE:PS50868 InterPro:IPR000313 PROSITE:PS50812 SMART:SM00293 UniGene:Hs.434966 PDB:4GNE PDB:4GNF PDB:4GNG PDBsum:4GNE PDBsum:4GNF PDBsum:4GNG PharmGKB:PA37370 OrthoDB:EOG7Z69BG TreeFam:TF329088 HOVERGEN:HBG079979 EMBL:AF332468 EMBL:AF332469 EMBL:AJ295990 EMBL:AJ295991 EMBL:AJ295992 EMBL:AF255649 EMBL:AK000360 EMBL:AK022560 EMBL:AK127594 EMBL:BC012059 EMBL:BC062631 EMBL:BC101717 EMBL:BC107734 EMBL:BC113469 EMBL:BC115006 RefSeq:NP_060248.2 RefSeq:NP_075447.1 RefSeq:XP_005273605.1 UniGene:Hs.608111 UniGene:Hs.655314 PDB:2DAQ PDB:4GND PDBsum:2DAQ PDBsum:4GND ProteinModelPortal:Q9BZ95 SMR:Q9BZ95 BioGrid:120250 IntAct:Q9BZ95 MINT:MINT-4830664 PhosphoSite:Q9BZ95 DMDM:74761342 PaxDb:Q9BZ95 PRIDE:Q9BZ95 DNASU:54904 Ensembl:ENST00000316985 Ensembl:ENST00000317025 Ensembl:ENST00000433384 GeneID:54904 KEGG:hsa:54904 UCSC:uc003xli.3 UCSC:uc003xlj.3 UCSC:uc010lwe.3 CTD:54904 GeneCards:GC08M038151 HGNC:HGNC:12767 HPA:CAB013721 HPA:HPA005659 HPA:HPA018893 MIM:607083 neXtProt:NX_Q9BZ95 InParanoid:Q9BZ95 KO:K11425 OMA:MEKDIHK ChiTaRS:WHSC1L1 EvolutionaryTrace:Q9BZ95 GeneWiki:WHSC1L1 GenomeRNAi:54904 NextBio:57940 PRO:PR:Q9BZ95 ArrayExpress:Q9BZ95 Bgee:Q9BZ95 Genevestigator:Q9BZ95 Uniprot:Q9BZ95)

HSP 1 Score: 60.8474 bits (146), Expect = 3.771e-8
Identity = 41/144 (28.47%), Postives = 72/144 (50.00%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKFPKRKKDFEPGKKFRN---IFERA-----VKEAEAXMCIPVALRLEKLGFVYIPTNIDGATRNVLAKKKKS 210
            G L+W+K+  + +WP + + DP   V +K+     R + H+ F +    RAWV+E  V  Y+G+++++EL  +  K+  +    +K R      ERA     +  AE  + +    R+E+  F+Y    ID      L++ KKS
Sbjct:  271 GDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAR-EYHVQFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERIEQYTFIY----IDKQPEEALSQAKKS 409          
BLAST of EMLSAG00000003515 vs. GO
Match: - (symbol:WHSC1L1 "Uncharacterized protein" species:9615 "Canis lupus familiaris" [GO:0005634 "nucleus" evidence=IEA] [GO:0008270 "zinc ion binding" evidence=IEA] [GO:0018024 "histone-lysine N-methyltransferase activity" evidence=IEA] InterPro:IPR001841 Pfam:PF00856 InterPro:IPR001214 InterPro:IPR001965 InterPro:IPR006560 InterPro:IPR019787 PROSITE:PS50016 PROSITE:PS50280 PROSITE:PS51215 SMART:SM00184 SMART:SM00249 SMART:SM00317 SMART:SM00570 Pfam:PF00855 GO:GO:0005634 GO:GO:0008270 Gene3D:3.30.40.10 InterPro:IPR011011 InterPro:IPR013083 SUPFAM:SSF57903 InterPro:IPR019786 PROSITE:PS01359 GO:GO:0018024 GO:GO:0018022 InterPro:IPR003616 SMART:SM00508 PROSITE:PS50868 GeneTree:ENSGT00740000114921 InterPro:IPR000313 PROSITE:PS50812 SMART:SM00293 TreeFam:TF329088 OMA:MEKDIHK EMBL:AAEX03010393 Ensembl:ENSCAFT00000009828 Uniprot:E2QUJ0)

HSP 1 Score: 60.8474 bits (146), Expect = 4.286e-8
Identity = 44/152 (28.95%), Postives = 77/152 (50.66%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKFPKRKKDFEPGKKFRN---IFERA-----VKEAEAXMCIPVALRLEKLGFVYIPTNIDGA----TRNVLAKK--KKSRR 212
            G L+W+K+  + +WP + + DP   V +K+     R + H+ F +    RAWV+E  V  Y+G+++++EL  +  K+  +    +K R      ERA     +  AE  + +    R+E+  F+YI    + A     +NV +K   KK+RR
Sbjct:  271 GDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAR-EYHVQFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERIEQYTFIYIDKQPEEALSQGKKNVASKAEVKKTRR 421          
BLAST of EMLSAG00000003515 vs. GO
Match: - (symbol:MSH6 "Uncharacterized protein" species:9615 "Canis lupus familiaris" [GO:0000287 "magnesium ion binding" evidence=IEA] [GO:0000400 "four-way junction DNA binding" evidence=IEA] [GO:0000790 "nuclear chromatin" evidence=IEA] [GO:0003682 "chromatin binding" evidence=IEA] [GO:0005524 "ATP binding" evidence=IEA] [GO:0006298 "mismatch repair" evidence=IEA] [GO:0008340 "determination of adult lifespan" evidence=IEA] [GO:0008630 "intrinsic apoptotic signaling pathway in response to DNA damage" evidence=IEA] [GO:0009411 "response to UV" evidence=IEA] [GO:0016446 "somatic hypermutation of immunoglobulin genes" evidence=IEA] [GO:0016887 "ATPase activity" evidence=IEA] [GO:0032137 "guanine/thymine mispair binding" evidence=IEA] [GO:0032142 "single guanine insertion binding" evidence=IEA] [GO:0032143 "single thymine insertion binding" evidence=IEA] [GO:0032301 "MutSalpha complex" evidence=IEA] [GO:0032357 "oxidized purine DNA binding" evidence=IEA] [GO:0032405 "MutLalpha complex binding" evidence=IEA] [GO:0035064 "methylated histone residue binding" evidence=IEA] [GO:0043531 "ADP binding" evidence=IEA] [GO:0045190 "isotype switching" evidence=IEA] [GO:0045910 "negative regulation of DNA recombination" evidence=IEA] [GO:0051096 "positive regulation of helicase activity" evidence=IEA] InterPro:IPR000432 InterPro:IPR007695 InterPro:IPR007696 InterPro:IPR007860 InterPro:IPR007861 InterPro:IPR015536 InterPro:IPR016151 Pfam:PF00488 Pfam:PF01624 Pfam:PF05188 Pfam:PF05190 Pfam:PF05192 SMART:SM00533 SMART:SM00534 Pfam:PF00855 InterPro:IPR027417 SUPFAM:SSF52540 GO:GO:0005524 GO:GO:0008340 GO:GO:0009411 GO:GO:0008630 GO:GO:0000287 GO:GO:0006298 GO:GO:0043531 GO:GO:0003682 GO:GO:0016887 GO:GO:0000790 GO:GO:0016446 GO:GO:0045190 InterPro:IPR000313 PROSITE:PS50812 GO:GO:0045910 SMART:SM00293 GO:GO:0051096 SUPFAM:SSF48334 GO:GO:0000400 GO:GO:0032137 GO:GO:0032301 Gene3D:3.40.1170.10 SUPFAM:SSF55271 GO:GO:0032357 GO:GO:0032142 GO:GO:0032143 InterPro:IPR017261 PANTHER:PTHR11361:SF31 PIRSF:PIRSF037677 OMA:HMDAVIG GeneTree:ENSGT00550000075024 TreeFam:TF105842 EMBL:AAEX03007503 Ensembl:ENSCAFT00000043509 Uniprot:J9P5H1)

HSP 1 Score: 60.4622 bits (145), Expect = 5.681e-8
Identity = 23/55 (41.82%), Postives = 34/55 (61.82%), Query Frame = 0
Query:  296 GTLIWGHMAGFPYWPCFV-TRSSDGDYIREAKNKISVHVQFFNWNDESGWVTKTM 349
            G L+W  M G+P+WPC V     DG +IRE    + +HVQFF+ +   GWV++ +
Sbjct:   11 GDLVWAKMEGYPWWPCLVYNHPFDGTFIREKGKSVRIHVQFFDDSPTRGWVSRRL 65          
BLAST of EMLSAG00000003515 vs. C. finmarchicus
Match: gi|592768106|gb|GAXK01186462.1| (TSA: Calanus finmarchicus comp45570_c1_seq1 transcribed RNA sequence)

HSP 1 Score: 119.398 bits (298), Expect = 1.032e-26
Identity = 78/227 (34.36%), Postives = 111/227 (48.90%), Query Frame = 0
Query:  290 DNLPKLGTLIWGHMAGFPYWPCFVTRSSDGDYIREA-KNKISVHVQFFNWNDESGWVTKTMPWCSVAEFRRFAKEAIKEDVSCSMDWSPV-GKMLHKWKNAALQAESTVHLSRKERHKRFL---------------VKIKKNIVMNRRIINNGFRVSDDHININASKSPISKFKTPPPPIVTTSTRLPPGWIIRCYKEEDYGKESRTEYQSPDGAVFLKIENAISYL 499
            D  PK+G L+WG M+GFP+WP FVT+S  G Y RE    K S HVQFFNWNDESGWV   + +  +  F++ A +  K D S    ++P  G M+ KW+ AA +AE T+ L+R ER +++L               V+  K   + +         +     +  +  P SK      P      +LP GW IR   E   G ++   + SPDG  F     A+ Y+
Sbjct:  711 DEFPKIGDLVWGRMSGFPFWPSFVTKSPTGQYRREGPSGKASYHVQFFNWNDESGWVNAVIEFDGLDSFKKIAAKK-KTDKS----YNPSKGAMMSKWEKAAREAEETMGLTRLERFEQYLVIYGVNNPKAPKPSPVRAPKPAPIPKPKKVPVPAAAAVPPPVKRTPGPASKTGVKRSPQAEAGGQLPAGWRIRNRAE---GGQT---FISPDGREFQDKTAALRYI 1358          

HSP 2 Score: 101.679 bits (252), Expect = 3.274e-21
Identity = 57/150 (38.00%), Postives = 85/150 (56.67%), Query Frame = 0
Query:   61 IHKSCSLSDQMTIEGCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRT--KTHIHFLAYDNLRAWVNESDVLSYEGYEKFK-ELAYKFPKRKKDFEPGKKFRNIFERAVKEAEAXMCIPVALRLE----KLGFVYIPTNIDGATRNV 203
            I     L+ +  +EG L+WAKI+G+ YWP + T DP +G   KV +S  +T  K H+ FL Y+N RAW+  +    Y+G ++F+ E A     RKKDF PGK+++  FE+AV  +E+ + +    RLE    K G+V +     G  R V
Sbjct: 1854 IKSGSELNSEDLVEGSLVWAKIKGYPYWPSVVTRDPADGEFVKVPDSQFKTQRKCHVLFLEYNNQRAWLPSTSFKEYKGRQEFQAEAAKAVSNRKKDFIPGKRYQAQFEKAVTFSESLVTLTNEERLEVVLLKYGWVMVSEPGSGEERGV 2303          

HSP 3 Score: 63.1586 bits (152), Expect = 2.726e-9
Identity = 37/123 (30.08%), Postives = 65/123 (52.85%), Query Frame = 0
Query:  296 GTLIWGHMAGFPYWPCFVTRS-SDGDYIR----EAKNKISVHVQFFNWNDESGWVTKTMPWCSVAEFR---RFAKEAIKEDVSCSMDWSPVGKMLHKWKNAALQAESTVHLSRKERHKRFLVK 410
            G+L+W  + G+PYWP  VTR  +DG++++    + K +   HV F  +N++  W    +P  S  E++    F  EA K   +   D+ P  +   +++ A   +ES V L+ +ER +  L+K
Sbjct: 1905 GSLVWAKIKGYPYWPSVVTRDPADGEFVKVPDSQFKTQRKCHVLFLEYNNQRAW----LPSTSFKEYKGRQEFQAEAAKAVSNRKKDFIPGKRYQAQFEKAVTFSESLVTLTNEERLEVVLLK 2261          

HSP 4 Score: 57.3806 bits (137), Expect = 1.487e-7
Identity = 37/127 (29.13%), Postives = 60/127 (47.24%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPY-----EGVTSKVIESSKRTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKFPKRKKDFEPGK-KFRNIFERAVKEAEAXMCIPVALRLEKLGFVYIPTN 195
            G L+W ++ GF +WP   T  P      EG + K          H+ F  +++   WVN   V+ ++G + FK++A K  K  K + P K    + +E+A +EAE  M +    R E+   +Y   N
Sbjct:  990 GDLVWGRMSGFPFWPSFVTKSPTGQYRREGPSGKA-------SYHVQFFNWNDESGWVNA--VIEFDGLDSFKKIAAK-KKTDKSYNPSKGAMMSKWEKAAREAEETMGLTRLERFEQYLVIYGVNN 1340          

HSP 5 Score: 38.5058 bits (88), Expect = 1.038e-1
Identity = 20/87 (22.99%), Postives = 39/87 (44.83%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVI----------------ESSKRTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKELA 145
            G L+W +  G SY P + + DP+    +K++                E     + H+ +L  DN R W+    ++ Y+G   ++++A
Sbjct: 3054 GDLVWGRTMGSSYHPCVVSQDPHFRFHTKIVKAEPGIGLESPPPPGKEGVGERQYHVQYLG-DNKRVWLPSKQIIPYKGIAHYEQMA 3311          

HSP 6 Score: 33.4982 bits (75), Expect = 3.352e+0
Identity = 30/134 (22.39%), Postives = 56/134 (41.79%), Query Frame = 0
Query:  295 LGTLIWGHMAGFPYWPCFVT------------RSSDGDYI-------REAKNKISVHVQFFNWNDESGWV--TKTMPWCSVAEFRRFAKEAIKEDVSCSMDWSPVGKMLH-KWKNAALQAESTVHLSRKERHKR 406
            +G L+WG   G  Y PC V+            ++  G  +       +E   +   HVQ+   N    W+   + +P+  +A + + A + +K   + +  + P  + L   W+ A L A+    L+ +ER  R
Sbjct: 2925 VGDLVWGRTMGSSYHPCVVSQDPHFRFHTKIVKAEPGIGLESPPPPGKEGVGERQYHVQYLGDNKRV-WLPSKQIIPYKGIAHYEQMAIQDVK---NINKIYKPKTEALKTAWREAVLLAQQLEQLTSQERISR 3314          
BLAST of EMLSAG00000003515 vs. C. finmarchicus
Match: gi|592950526|gb|GAXK01008027.1| (TSA: Calanus finmarchicus comp137877_c0_seq4 transcribed RNA sequence)

HSP 1 Score: 59.3066 bits (142), Expect = 3.820e-8
Identity = 37/117 (31.62%), Postives = 59/117 (50.43%), Query Frame = 0
Query:   74 EGCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSK--RTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKFPKR-KKDFEPGKKFRNIFERAVKEAEAXMCIPVALRLEKL 187
            EG L+WA+++G+ +WP +      E  T      SK  R + H+ FLAY    AWV E+ ++ +   ++FK       K+ +KDF P K   +   +AV+ A   +   +  RLE L
Sbjct: 1902 EGMLVWARVQGYPFWPAVIV---REQRTEHFSNPSKGGRARIHVMFLAYQKQTAWVGEAALVPFYVADQFKTFIVSGNKKSQKDFVPTKTMASKHSQAVELATQLLPKSLYNRLEYL 2243          

HSP 2 Score: 49.6766 bits (117), Expect = 3.254e-5
Identity = 21/55 (38.18%), Postives = 32/55 (58.18%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKTHIHFLAYDNLRAWVNE 129
            G L+WAK++G+  WP I   DP  G + +V +  K    H+ FL Y N  AW+++
Sbjct: 2667 GSLVWAKMKGYPSWPAIVVPDPLTGKSREVRKGKKGEWRHVLFLEYRNEVAWLHQ 2831          

HSP 3 Score: 43.1282 bits (100), Expect = 3.321e-3
Identity = 16/69 (23.19%), Postives = 33/69 (47.83%), Query Frame = 0
Query:  296 GTLIWGHMAGFPYWPCFVTRSSDGDYIREAK--NKISVHVQFFNWNDESGWVTKT--MPWCSVAEFRRF 360
            G L+W  + G+P+WP  + R    ++        +  +HV F  +  ++ WV +   +P+    +F+ F
Sbjct: 2034 GMLVWARVQGYPFWPAVIVREQRTEHFSNPSKGGRARIHVMFLAYQKQTAWVGEAALVPFYVADQFKTF 2240          

HSP 4 Score: 38.891 bits (89), Expect = 7.176e-2
Identity = 20/76 (26.32%), Postives = 36/76 (47.37%), Query Frame = 0
Query:  274 DSDLLSD-YENTCDNTKDNLPKLGTLIWGHMAGFPYWPCFVT---RSSDGDYIREAKNKISVHVQFFNWNDESGWV 345
            D D+ SD +    + + + +  +G+L+W  M G+P WP  V     +     +R+ K     HV F  + +E  W+
Sbjct: 2673 DHDVHSDEHGGDQEQSSEIVGPVGSLVWAKMKGYPSWPAIVVPDPLTGKSREVRKGKKGEWRHVLFLEYRNEVAWL 2900          
BLAST of EMLSAG00000003515 vs. C. finmarchicus
Match: gi|592950528|gb|GAXK01008025.1| (TSA: Calanus finmarchicus comp137877_c0_seq2 transcribed RNA sequence)

HSP 1 Score: 59.3066 bits (142), Expect = 3.855e-8
Identity = 37/117 (31.62%), Postives = 59/117 (50.43%), Query Frame = 0
Query:   74 EGCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSK--RTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKFPKR-KKDFEPGKKFRNIFERAVKEAEAXMCIPVALRLEKL 187
            EG L+WA+++G+ +WP +      E  T      SK  R + H+ FLAY    AWV E+ ++ +   ++FK       K+ +KDF P K   +   +AV+ A   +   +  RLE L
Sbjct: 1902 EGMLVWARVQGYPFWPAVIV---REQRTEHFSNPSKGGRARIHVMFLAYQKQTAWVGEAALVPFYVADQFKTFIVSGNKKSQKDFVPTKTMASKHSQAVELATQLLPKSLYNRLEYL 2243          

HSP 2 Score: 49.6766 bits (117), Expect = 3.277e-5
Identity = 21/55 (38.18%), Postives = 32/55 (58.18%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKTHIHFLAYDNLRAWVNE 129
            G L+WAK++G+  WP I   DP  G + +V +  K    H+ FL Y N  AW+++
Sbjct: 2667 GSLVWAKMKGYPSWPAIVVPDPLTGKSREVRKGKKGEWRHVLFLEYRNEVAWLHQ 2831          

HSP 3 Score: 43.1282 bits (100), Expect = 3.341e-3
Identity = 16/69 (23.19%), Postives = 33/69 (47.83%), Query Frame = 0
Query:  296 GTLIWGHMAGFPYWPCFVTRSSDGDYIREAK--NKISVHVQFFNWNDESGWVTKT--MPWCSVAEFRRF 360
            G L+W  + G+P+WP  + R    ++        +  +HV F  +  ++ WV +   +P+    +F+ F
Sbjct: 2034 GMLVWARVQGYPFWPAVIVREQRTEHFSNPSKGGRARIHVMFLAYQKQTAWVGEAALVPFYVADQFKTF 2240          

HSP 4 Score: 38.891 bits (89), Expect = 7.211e-2
Identity = 20/76 (26.32%), Postives = 36/76 (47.37%), Query Frame = 0
Query:  274 DSDLLSD-YENTCDNTKDNLPKLGTLIWGHMAGFPYWPCFVT---RSSDGDYIREAKNKISVHVQFFNWNDESGWV 345
            D D+ SD +    + + + +  +G+L+W  M G+P WP  V     +     +R+ K     HV F  + +E  W+
Sbjct: 2673 DHDVHSDEHGGDQEQSSEIVGPVGSLVWAKMKGYPSWPAIVVPDPLTGKSREVRKGKKGEWRHVLFLEYRNEVAWL 2900          
BLAST of EMLSAG00000003515 vs. C. finmarchicus
Match: gi|592950527|gb|GAXK01008026.1| (TSA: Calanus finmarchicus comp137877_c0_seq3 transcribed RNA sequence)

HSP 1 Score: 59.3066 bits (142), Expect = 3.991e-8
Identity = 37/117 (31.62%), Postives = 59/117 (50.43%), Query Frame = 0
Query:   74 EGCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSK--RTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKFPKR-KKDFEPGKKFRNIFERAVKEAEAXMCIPVALRLEKL 187
            EG L+WA+++G+ +WP +      E  T      SK  R + H+ FLAY    AWV E+ ++ +   ++FK       K+ +KDF P K   +   +AV+ A   +   +  RLE L
Sbjct: 1902 EGMLVWARVQGYPFWPAVIV---REQRTEHFSNPSKGGRARIHVMFLAYQKQTAWVGEAALVPFYVADQFKTFIVSGNKKSQKDFVPTKTMASKHSQAVELATQLLPKSLYNRLEYL 2243          

HSP 2 Score: 50.0618 bits (118), Expect = 3.095e-5
Identity = 21/55 (38.18%), Postives = 32/55 (58.18%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKTHIHFLAYDNLRAWVNE 129
            G L+WAK++G+  WP I   DP  G + +V +  K    H+ FL Y N  AW+++
Sbjct: 2667 GSLVWAKMKGYPSWPAIVVPDPLTGKSREVRKGKKGEWRHVLFLEYRNEVAWLHQ 2831          

HSP 3 Score: 43.1282 bits (100), Expect = 3.324e-3
Identity = 16/69 (23.19%), Postives = 33/69 (47.83%), Query Frame = 0
Query:  296 GTLIWGHMAGFPYWPCFVTRSSDGDYIREAK--NKISVHVQFFNWNDESGWVTKT--MPWCSVAEFRRF 360
            G L+W  + G+P+WP  + R    ++        +  +HV F  +  ++ WV +   +P+    +F+ F
Sbjct: 2034 GMLVWARVQGYPFWPAVIVREQRTEHFSNPSKGGRARIHVMFLAYQKQTAWVGEAALVPFYVADQFKTF 2240          

HSP 4 Score: 38.891 bits (89), Expect = 6.940e-2
Identity = 20/76 (26.32%), Postives = 36/76 (47.37%), Query Frame = 0
Query:  274 DSDLLSD-YENTCDNTKDNLPKLGTLIWGHMAGFPYWPCFVT---RSSDGDYIREAKNKISVHVQFFNWNDESGWV 345
            D D+ SD +    + + + +  +G+L+W  M G+P WP  V     +     +R+ K     HV F  + +E  W+
Sbjct: 2673 DHDVHSDEHGGDQEQSSEIVGPVGSLVWAKMKGYPSWPAIVVPDPLTGKSREVRKGKKGEWRHVLFLEYRNEVAWL 2900          
BLAST of EMLSAG00000003515 vs. C. finmarchicus
Match: gi|592950529|gb|GAXK01008024.1| (TSA: Calanus finmarchicus comp137877_c0_seq1 transcribed RNA sequence)

HSP 1 Score: 59.3066 bits (142), Expect = 4.028e-8
Identity = 37/117 (31.62%), Postives = 59/117 (50.43%), Query Frame = 0
Query:   74 EGCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSK--RTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKFPKR-KKDFEPGKKFRNIFERAVKEAEAXMCIPVALRLEKL 187
            EG L+WA+++G+ +WP +      E  T      SK  R + H+ FLAY    AWV E+ ++ +   ++FK       K+ +KDF P K   +   +AV+ A   +   +  RLE L
Sbjct: 1902 EGMLVWARVQGYPFWPAVIV---REQRTEHFSNPSKGGRARIHVMFLAYQKQTAWVGEAALVPFYVADQFKTFIVSGNKKSQKDFVPTKTMASKHSQAVELATQLLPKSLYNRLEYL 2243          

HSP 2 Score: 50.0618 bits (118), Expect = 3.117e-5
Identity = 21/55 (38.18%), Postives = 32/55 (58.18%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKTHIHFLAYDNLRAWVNE 129
            G L+WAK++G+  WP I   DP  G + +V +  K    H+ FL Y N  AW+++
Sbjct: 2667 GSLVWAKMKGYPSWPAIVVPDPLTGKSREVRKGKKGEWRHVLFLEYRNEVAWLHQ 2831          

HSP 3 Score: 43.1282 bits (100), Expect = 3.343e-3
Identity = 16/69 (23.19%), Postives = 33/69 (47.83%), Query Frame = 0
Query:  296 GTLIWGHMAGFPYWPCFVTRSSDGDYIREAK--NKISVHVQFFNWNDESGWVTKT--MPWCSVAEFRRF 360
            G L+W  + G+P+WP  + R    ++        +  +HV F  +  ++ WV +   +P+    +F+ F
Sbjct: 2034 GMLVWARVQGYPFWPAVIVREQRTEHFSNPSKGGRARIHVMFLAYQKQTAWVGEAALVPFYVADQFKTF 2240          

HSP 4 Score: 38.891 bits (89), Expect = 6.975e-2
Identity = 20/76 (26.32%), Postives = 36/76 (47.37%), Query Frame = 0
Query:  274 DSDLLSD-YENTCDNTKDNLPKLGTLIWGHMAGFPYWPCFVT---RSSDGDYIREAKNKISVHVQFFNWNDESGWV 345
            D D+ SD +    + + + +  +G+L+W  M G+P WP  V     +     +R+ K     HV F  + +E  W+
Sbjct: 2673 DHDVHSDEHGGDQEQSSEIVGPVGSLVWAKMKGYPSWPAIVVPDPLTGKSREVRKGKKGEWRHVLFLEYRNEVAWL 2900          
BLAST of EMLSAG00000003515 vs. C. finmarchicus
Match: gi|592798956|gb|GAXK01155612.1| (TSA: Calanus finmarchicus comp105552_c9_seq2 transcribed RNA sequence)

HSP 1 Score: 48.521 bits (114), Expect = 8.201e-5
Identity = 33/132 (25.00%), Postives = 65/132 (49.24%), Query Frame = 0
Query:   77 LLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRT-----KTHIHFLAYDNLRAWVNESDVLSYEGYEKF----KELAYKFPKRK---------KDFEPGKKFRNIFERAVKEAEAXMCIPVALRLEKLGFV 190
            ++WA++    +WP + T D  EG+  + I+ ++       + H+ F   +N RAWV+E+ +  + G E F    KE+      +K         K F P  + ++ +  +V+ AE+ + +P   R+ K+G +
Sbjct: 10705 IVWARVGTHPWWPAMVTND-EEGLKCERIKPTRMGHRPLWEIHVSFFG-ENTRAWVDENHLKLFNGAESFEKEKKEVLGDISNKKTYKQKEKLLKAFTPTNQLKDRWMASVQGAESVLSVPEHRRMTKMGAI 11094          

HSP 2 Score: 32.3426 bits (72), Expect = 8.524e+0
Identity = 28/131 (21.37%), Postives = 50/131 (38.17%), Query Frame = 0
Query:  295 LGTLIWGHMAGFPYWPCFVTRSSDGDYIREAKNKI-------SVHVQFFNWNDESGWVTKT-MPWCSVAE-FRRFAKEAI---------KEDVSCSMDWSPVGKMLHKWKNAALQAESTVHLSRKERHKRF 407
            L  ++W  +   P+WP  VT   +G      K           +HV FF  N  + WV +  +   + AE F +  KE +         K+       ++P  ++  +W  +   AES + +    R  + 
Sbjct: 10714 LAEIVWARVGTHPWWPAMVTNDEEGLKCERIKPTRMGHRPLWEIHVSFFGENTRA-WVDENHLKLFNGAESFEKEKKEVLGDISNKKTYKQKEKLLKAFTPTNQLKDRWMASVQGAESVLSVPEHRRMTKM 11103          
BLAST of EMLSAG00000003515 vs. C. finmarchicus
Match: gi|592798957|gb|GAXK01155611.1| (TSA: Calanus finmarchicus comp105552_c9_seq1 transcribed RNA sequence)

HSP 1 Score: 48.521 bits (114), Expect = 8.202e-5
Identity = 33/132 (25.00%), Postives = 65/132 (49.24%), Query Frame = 0
Query:   77 LLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRT-----KTHIHFLAYDNLRAWVNESDVLSYEGYEKF----KELAYKFPKRK---------KDFEPGKKFRNIFERAVKEAEAXMCIPVALRLEKLGFV 190
            ++WA++    +WP + T D  EG+  + I+ ++       + H+ F   +N RAWV+E+ +  + G E F    KE+      +K         K F P  + ++ +  +V+ AE+ + +P   R+ K+G +
Sbjct: 10705 IVWARVGTHPWWPAMVTND-EEGLKCERIKPTRMGHRPLWEIHVSFFG-ENTRAWVDENHLKLFNGAESFEKEKKEVLGDISNKKTYKQKEKLLKAFTPTNQLKDRWMASVQGAESVLSVPEHRRMTKMGAI 11094          

HSP 2 Score: 32.3426 bits (72), Expect = 8.525e+0
Identity = 28/131 (21.37%), Postives = 50/131 (38.17%), Query Frame = 0
Query:  295 LGTLIWGHMAGFPYWPCFVTRSSDGDYIREAKNKI-------SVHVQFFNWNDESGWVTKT-MPWCSVAE-FRRFAKEAI---------KEDVSCSMDWSPVGKMLHKWKNAALQAESTVHLSRKERHKRF 407
            L  ++W  +   P+WP  VT   +G      K           +HV FF  N  + WV +  +   + AE F +  KE +         K+       ++P  ++  +W  +   AES + +    R  + 
Sbjct: 10714 LAEIVWARVGTHPWWPAMVTNDEEGLKCERIKPTRMGHRPLWEIHVSFFGENTRA-WVDENHLKLFNGAESFEKEKKEVLGDISNKKTYKQKEKLLKAFTPTNQLKDRWMASVQGAESVLSVPEHRRMTKM 11103          
BLAST of EMLSAG00000003515 vs. C. finmarchicus
Match: gi|592825260|gb|GAXK01129929.1| (TSA: Calanus finmarchicus comp71342_c0_seq1 transcribed RNA sequence)

HSP 1 Score: 48.1358 bits (113), Expect = 1.035e-4
Identity = 30/118 (25.42%), Postives = 52/118 (44.07%), Query Frame = 0
Query:  295 LGTLIWGHMAGFPYWPCFV-TRSSDGDYIREAKNKISVHVQFFNWNDESGWVTKTMPWCSVAEFRRFAKEAIKEDVSCSMDWSPVGKMLHKWKNAALQAESTVHLSRKERHKRFLVKI 411
            LG+L+W  ++G+P+WP  V    +D    R+ +    VHV F +      WV+ TM        +++ +  +K+           G     W+     AE+   LS +ER +  LV +
Sbjct:  189 LGSLVWAKLSGYPWWPSMVCNHPTDQKSARKGE----VHVMFLDTPVNRSWVSDTM-------IKKWGESVLKD-----------GAGDRNWEKGVKDAEAVAGLSDEERLETLLVNL 476          

HSP 2 Score: 45.4394 bits (106), Expect = 7.443e-4
Identity = 32/121 (26.45%), Postives = 58/121 (47.93%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKFPKRKKDFEPGKKFRNIFERAVKEAEAXMCIPVALRLEKLGFVYIPTN 195
            G L+WAK+ G+ +WP +    P +       +S+++ + H+ FL     R+WV+++ +  + G    K+              G   RN +E+ VK+AEA   +    RLE L    +P++
Sbjct:  192 GSLVWAKLSGYPWWPSMVCNHPTDQ------KSARKGEVHVMFLDTPVNRSWVSDTMIKKW-GESVLKD--------------GAGDRN-WEKGVKDAEAVAGLSDEERLETLLVNLLPSD 488          
BLAST of EMLSAG00000003515 vs. C. finmarchicus
Match: gi|592875291|gb|GAXK01082286.1| (TSA: Calanus finmarchicus comp112014_c8_seq11 transcribed RNA sequence)

HSP 1 Score: 46.2098 bits (108), Expect = 1.089e-4
Identity = 20/72 (27.78%), Postives = 33/72 (45.83%), Query Frame = 0
Query:  296 GTLIWGHMAGFPYWPCFVTRS----SDGDYIREAKNKISVHVQFFNWNDESGWVTKTMPWCSVAEFRRFAKE 363
            G ++W H  G+P+WP  ++ S    + G +      K   H  F  WN E  W+  T       E+++F +E
Sbjct:   71 GDVVWAHQKGYPWWPAVISPSPANPNQGQWQVGVGKKTRYHCTFLEWNRERSWLEGT-------EYKKFKRE 265          

HSP 2 Score: 40.4318 bits (93), Expect = 8.736e-3
Identity = 30/114 (26.32%), Postives = 57/114 (50.00%), Query Frame = 0
Query:   74 EGCLLWAKIRGFSYWPGITT---VDPYEGVTSKVIESSKRTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKFPKRKKDFEPGKKFRNIFERAVKEAEAXMCIPVALRL 184
            EG ++WA  +G+ +WP + +    +P +G     +   K+T+ H  FL ++  R+W+  ++      Y+KF        KR+   E  KK  N+  R  K++   + I +AL++
Sbjct:   68 EGDVVWAHQKGYPWWPAVISPSPANPNQGQWQ--VGVGKKTRYHCTFLEWNRERSWLEGTE------YKKF--------KREDGGEGRKKEYNVKRREYKDSH-LVAIELALQI 358          
BLAST of EMLSAG00000003515 vs. C. finmarchicus
Match: gi|592896801|gb|GAXK01061574.1| (TSA: Calanus finmarchicus comp645744_c0_seq5 transcribed RNA sequence)

HSP 1 Score: 47.3654 bits (111), Expect = 1.188e-4
Identity = 24/70 (34.29%), Postives = 33/70 (47.14%), Query Frame = 0
Query:  296 GTLIWGHMAGFPYWPCFVTRSSD----GDYIREAKNKISVHVQFFNWNDESGWVTKTMPWCS-VAEFRRF 360
            G ++W  M G+P+WP  V+ +S     G +      KI  H  F  WN E+ W+      CS V  FRR 
Sbjct:   54 GEVVWARMTGYPWWPAVVSPASTPPHLGMWKVGVGKKIRYHCTFLAWNKETAWIG-----CSRVRRFRRI 248          

HSP 2 Score: 38.5058 bits (88), Expect = 7.207e-2
Identity = 19/69 (27.54%), Postives = 36/69 (52.17%), Query Frame = 0
Query:   74 EGCLLWAKIRGFSYWPGI---TTVDPYEGVTSKVIESSKRTKTHIHFLAYDNLRAWVNESDVLSYEGYE 139
            EG ++WA++ G+ +WP +    +  P+ G+    +   K+ + H  FLA++   AW+  S V  +   E
Sbjct:   51 EGEVVWARMTGYPWWPAVVSPASTPPHLGMWK--VGVGKKIRYHCTFLAWNKETAWIGCSRVRRFRRIE 251          
BLAST of EMLSAG00000003515 vs. L. salmonis peptides
Match: EMLSAP00000003515 (pep:novel supercontig:LSalAtl2s:LSalAtl2s191:6249:9076:-1 gene:EMLSAG00000003515 transcript:EMLSAT00000003515 description:"maker-LSalAtl2s191-augustus-gene-0.18")

HSP 1 Score: 1471.06 bits (3807), Expect = 0.000e+0
Identity = 708/708 (100.00%), Postives = 708/708 (100.00%), Query Frame = 0
Query:    1 MATVISRFVKMSLSEEERPSLTAEDSDDSGVHLKQSRMSDCDPDSDGRTQGCVEMDFSQKIHKSCSLSDQMTIEGCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKFPKRKKDFEPGKKFRNIFERAVKEAEAXMCIPVALRLEKLGFVYIPTNIDGATRNVLAKKKKSRRRSSKTSESENISSKFPLYQTVSRNDHQNIQGRQLPRRNPSHLIDTKSKDIYEFVDDETNASDSDLLSDYENTCDNTKDNLPKLGTLIWGHMAGFPYWPCFVTRSSDGDYIREAKNKISVHVQFFNWNDESGWVTKTMPWCSVAEFRRFAKEAIKEDVSCSMDWSPVGKMLHKWKNAALQAESTVHLSRKERHKRFLVKIKKNIVMNRRIINNGFRVSDDHININASKSPISKFKTPPPPIVTTSTRLPPGWIIRCYKEEDYGKESRTEYQSPDGAVFLKIENAISYLFQQNNSGIRKRSYSTPGGCIASDYSSLSCLSPSPACKKRRLDAGWFIYESDQHRYSSXLLHTSLPRGWSVKRIRMGRNPEVQSSYLSPECKTYSKVPQEWPSRREFFSKAAAASYLEGMGHPAVELEHVIVTGMIQCLSRKDHFLKVDDYLDYRLSETPELRKIVDPTFVKVTPLPKDIYRHSSVLVEEKDGKFQLKDVNSVPLSLNGN 708
            MATVISRFVKMSLSEEERPSLTAEDSDDSGVHLKQSRMSDCDPDSDGRTQGCVEMDFSQKIHKSCSLSDQMTIEGCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKFPKRKKDFEPGKKFRNIFERAVKEAEAXMCIPVALRLEKLGFVYIPTNIDGATRNVLAKKKKSRRRSSKTSESENISSKFPLYQTVSRNDHQNIQGRQLPRRNPSHLIDTKSKDIYEFVDDETNASDSDLLSDYENTCDNTKDNLPKLGTLIWGHMAGFPYWPCFVTRSSDGDYIREAKNKISVHVQFFNWNDESGWVTKTMPWCSVAEFRRFAKEAIKEDVSCSMDWSPVGKMLHKWKNAALQAESTVHLSRKERHKRFLVKIKKNIVMNRRIINNGFRVSDDHININASKSPISKFKTPPPPIVTTSTRLPPGWIIRCYKEEDYGKESRTEYQSPDGAVFLKIENAISYLFQQNNSGIRKRSYSTPGGCIASDYSSLSCLSPSPACKKRRLDAGWFIYESDQHRYSSXLLHTSLPRGWSVKRIRMGRNPEVQSSYLSPECKTYSKVPQEWPSRREFFSKAAAASYLEGMGHPAVELEHVIVTGMIQCLSRKDHFLKVDDYLDYRLSETPELRKIVDPTFVKVTPLPKDIYRHSSVLVEEKDGKFQLKDVNSVPLSLNGN
Sbjct:    1 MATVISRFVKMSLSEEERPSLTAEDSDDSGVHLKQSRMSDCDPDSDGRTQGCVEMDFSQKIHKSCSLSDQMTIEGCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKFPKRKKDFEPGKKFRNIFERAVKEAEAXMCIPVALRLEKLGFVYIPTNIDGATRNVLAKKKKSRRRSSKTSESENISSKFPLYQTVSRNDHQNIQGRQLPRRNPSHLIDTKSKDIYEFVDDETNASDSDLLSDYENTCDNTKDNLPKLGTLIWGHMAGFPYWPCFVTRSSDGDYIREAKNKISVHVQFFNWNDESGWVTKTMPWCSVAEFRRFAKEAIKEDVSCSMDWSPVGKMLHKWKNAALQAESTVHLSRKERHKRFLVKIKKNIVMNRRIINNGFRVSDDHININASKSPISKFKTPPPPIVTTSTRLPPGWIIRCYKEEDYGKESRTEYQSPDGAVFLKIENAISYLFQQNNSGIRKRSYSTPGGCIASDYSSLSCLSPSPACKKRRLDAGWFIYESDQHRYSSXLLHTSLPRGWSVKRIRMGRNPEVQSSYLSPECKTYSKVPQEWPSRREFFSKAAAASYLEGMGHPAVELEHVIVTGMIQCLSRKDHFLKVDDYLDYRLSETPELRKIVDPTFVKVTPLPKDIYRHSSVLVEEKDGKFQLKDVNSVPLSLNGN 708          
BLAST of EMLSAG00000003515 vs. SwissProt
Match: gi|118572948|sp|Q6P2L6.2|NSD3_MOUSE (RecName: Full=Histone-lysine N-methyltransferase NSD3; AltName: Full=Nuclear SET domain-containing protein 3; AltName: Full=Wolf-Hirschhorn syndrome candidate 1-like protein 1 homolog; Short=WHSC1-like protein 1)

HSP 1 Score: 65.0846 bits (157), Expect = 1.747e-9
Identity = 49/166 (29.52%), Postives = 83/166 (50.00%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKFPKRKKDFEPGKKFRN---IFERA-----VKEAEAXMCIPVALRLEKLGFVYIPTNIDGAT----RNVLAK---KKKSRRRSSKTSESENISS 225
            G L+W+K+  + +WP + + DP   V SK+     R + H+ F +    RAWV+E  V  Y+G+E+++EL  +  K+  +    +K R      ERA     +  AE  + +    R+E+  F+YI    + A+    +NV +K   KK  R RS   S+ E  ++
Sbjct:  271 GDLVWSKVGTYPWWPCMVSSDPQLEVHSKINTRGAR-EYHVQFFSNQPERAWVHEKRVREYKGHEQYEELLAEAAKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERVEQYTFIYIDKQPEEASSQAKKNVTSKTEVKKPRRPRSVLNSQPEQTNA 435          
BLAST of EMLSAG00000003515 vs. SwissProt
Match: gi|68067672|sp|P52701.2|MSH6_HUMAN (RecName: Full=DNA mismatch repair protein Msh6; Short=hMSH6; AltName: Full=G/T mismatch-binding protein; Short=GTBP; Short=GTMBP; AltName: Full=MutS protein homolog 6; AltName: Full=MutS-alpha 160 kDa subunit; Short=p160)

HSP 1 Score: 62.003 bits (149), Expect = 1.466e-8
Identity = 25/55 (45.45%), Postives = 34/55 (61.82%), Query Frame = 0
Query:  296 GTLIWGHMAGFPYWPCFV-TRSSDGDYIREAKNKISVHVQFFNWNDESGWVTKTM 349
            G L+W  M G+P+WPC V     DG +IRE    + VHVQFF+ +   GWV+K +
Sbjct:   93 GDLVWAKMEGYPWWPCLVYNHPFDGTFIREKGKSVRVHVQFFDDSPTRGWVSKRL 147          
BLAST of EMLSAG00000003515 vs. SwissProt
Match: gi|341940990|sp|P54276.3|MSH6_MOUSE (RecName: Full=DNA mismatch repair protein Msh6; AltName: Full=G/T mismatch-binding protein; Short=GTBP; Short=GTMBP; AltName: Full=MutS protein homolog 6; AltName: Full=MutS-alpha 160 kDa subunit; Short=p160)

HSP 1 Score: 61.2326 bits (147), Expect = 2.225e-8
Identity = 25/55 (45.45%), Postives = 34/55 (61.82%), Query Frame = 0
Query:  296 GTLIWGHMAGFPYWPCFV-TRSSDGDYIREAKNKISVHVQFFNWNDESGWVTKTM 349
            G L+W  M G+P+WPC V     DG +IR+    + VHVQFF+ +   GWV+K M
Sbjct:   93 GDLVWAKMEGYPWWPCLVYNHPFDGTFIRKKGKSVRVHVQFFDDSPTRGWVSKRM 147          
BLAST of EMLSAG00000003515 vs. SwissProt
Match: gi|74761342|sp|Q9BZ95.1|NSD3_HUMAN (RecName: Full=Histone-lysine N-methyltransferase NSD3; AltName: Full=Nuclear SET domain-containing protein 3; AltName: Full=Protein whistle; AltName: Full=WHSC1-like 1 isoform 9 with methyltransferase activity to lysine; AltName: Full=Wolf-Hirschhorn syndrome candidate 1-like protein 1; Short=WHSC1-like protein 1)

HSP 1 Score: 60.8474 bits (146), Expect = 2.958e-8
Identity = 41/144 (28.47%), Postives = 72/144 (50.00%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKFPKRKKDFEPGKKFRN---IFERA-----VKEAEAXMCIPVALRLEKLGFVYIPTNIDGATRNVLAKKKKS 210
            G L+W+K+  + +WP + + DP   V +K+     R + H+ F +    RAWV+E  V  Y+G+++++EL  +  K+  +    +K R      ERA     +  AE  + +    R+E+  F+Y    ID      L++ KKS
Sbjct:  271 GDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAR-EYHVQFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERIEQYTFIY----IDKQPEEALSQAKKS 409          
BLAST of EMLSAG00000003515 vs. SwissProt
Match: gi|29427833|sp|Q8MT36.2|MES4_DROME (RecName: Full=Probable histone-lysine N-methyltransferase Mes-4; AltName: Full=Maternal-effect sterile 4 homolog)

HSP 1 Score: 59.6918 bits (143), Expect = 7.349e-8
Identity = 46/189 (24.34%), Postives = 84/189 (44.44%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRT---------KTHIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKF-----PKRKK--DFEPGKKFRNIFERAVKEAEAXMCIPVALRLEKLGFVYIPTNIDGATRNVLAKKKKSRRRSS-KTSESENISSKFPLYQTVSRNDHQNIQGRQL 246
            G L W K+  + +WP +   DP   +   +    +R+         + H+ F A +  R W+   ++L++ G + F ++  +      PK  K     P +    I+ +A++EA+A   IP + RLEK    Y          NV+   ++ R+R+     ++ ++ S   LY   S ++  N QG QL
Sbjct:  396 GDLFWGKVFSYCFWPCMVCPDPLGQIVGNMPSHPQRSSLDNANVPIQVHVRFFADNGRRNWIKPENLLTFAGLKAFDDMREELRIKHGPKSAKYRQMVPKRTKVVIWRQAIEEAQAMTQIPYSDRLEKFYQTY---------ENVVTLNRQKRKRTKYMMQDTSDVGSS--LYD--STDNLHNKQGTQL 571          
BLAST of EMLSAG00000003515 vs. SwissProt
Match: gi|118572947|sp|Q8BVE8.2|NSD2_MOUSE (RecName: Full=Histone-lysine N-methyltransferase NSD2; AltName: Full=Multiple myeloma SET domain-containing protein; Short=MMSET; AltName: Full=Nuclear SET domain-containing protein 2; Short=NSD2; AltName: Full=Wolf-Hirschhorn syndrome candidate 1 protein homolog; Short=WHSC1)

HSP 1 Score: 58.151 bits (139), Expect = 2.205e-7
Identity = 33/127 (25.98%), Postives = 63/127 (49.61%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKT-HIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKFPKRK-------KDFEP-GKKFRNIFERAVKEAEAXMCIPVALRLEKLGFVYI 192
            G L+W+K+ G+ +WP + + DP     +K+    K  +  H+ F      RAW+ E  ++++EG E+F++L  +  K+        K  +P   + R  +E  + +AE    + +  R  K  F+Y+
Sbjct:  223 GDLVWSKVSGYPWWPCMVSADPLLHNHTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEEQFEKLCQESAKQAPTKAEKIKLLKPISGRLRAQWEMGIVQAEEAASMSIEERKAKFTFLYV 349          
BLAST of EMLSAG00000003515 vs. SwissProt
Match: gi|74706096|sp|O96028.1|NSD2_HUMAN (RecName: Full=Histone-lysine N-methyltransferase NSD2; AltName: Full=Multiple myeloma SET domain-containing protein; Short=MMSET; AltName: Full=Nuclear SET domain-containing protein 2; Short=NSD2; AltName: Full=Protein trithorax-5; AltName: Full=Wolf-Hirschhorn syndrome candidate 1 protein; Short=WHSC1)

HSP 1 Score: 56.9954 bits (136), Expect = 4.284e-7
Identity = 34/127 (26.77%), Postives = 62/127 (48.82%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKT-HIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKFPKRK-------KDFEP-GKKFRNIFERAVKEAEAXMCIPVALRLEKLGFVYI 192
            G L+W+K+ G+ +WP + + DP     +K+    K  +  H+ F      RAW+ E  ++++EG  +F++L  +  K+        K  +P   K R  +E  + +AE    + V  R  K  F+Y+
Sbjct:  223 GDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYV 349          
BLAST of EMLSAG00000003515 vs. Select Arthropod Genomes
Match: gb|KPM03216.1| (histone-lysine N-methyltransferase Mes-4-like protein [Sarcoptes scabiei])

HSP 1 Score: 71.633 bits (174), Expect = 8.189e-12
Identity = 48/166 (28.92%), Postives = 85/166 (51.20%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKT--HIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKFPKRKKDFEPGKKFR---------NIFER---AVKEAEAXMCIPVALRLEKLGFVYIPTNIDGATRNVLAKKKKSRRRSSKTSESENISSK 226
            G L+WAK++G+ +WP + ++DP  G   ++  SS +     H+ +      R W N   V+ +EG+EK  E   K     KD +  K+ +         +I ++   ++ EAE  M +P+  R++ L F YI +N++  T     +  KS+  SS TS+S+ ++ K
Sbjct:  145 GDLIWAKMQGYPWWPCMISIDPETGTFCRIAGSSYKADRVYHVQYFGSQPYRGWTNIGMVMPFEGFEKLIE---KIQNEMKDLDRKKRSKIEAKYMVKNSILKKWNESISEAEEAMILPLKERVDLLTFNYI-SNVEKKT----PRPNKSKSDSSITSKSKTVTKK 302          
BLAST of EMLSAG00000003515 vs. Select Arthropod Genomes
Match: gb|EEC05044.1| (set domain protein, putative [Ixodes scapularis])

HSP 1 Score: 61.6178 bits (148), Expect = 6.611e-9
Identity = 37/133 (27.82%), Postives = 58/133 (43.61%), Query Frame = 0
Query:   73 IEGCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKELA------YKFPKRKKDFEPGKKFRNIFERAVKEAEAXMCIPVALRLEKLGFVYIPTNIDGA 199
            + G LLW+K+ G  +WP + + DP  G+ +K +    R   H+ +   D    W     ++ YEG  KF  +       Y  P RK+D          +  AV+EA   + +  + R  KL F Y  +   GA
Sbjct:   50 LVGDLLWSKVGGHPFWPCMVSFDPLSGIYTKTVRQQHRL-YHVQYFGDDAQHGWTQPGRIMPYEGLAKFVAMGNLERAPYNVPDRKRD---------AWRVAVQEATDALELTRSERKHKLTFEYYDSRSKGA 172          
BLAST of EMLSAG00000003515 vs. Select Arthropod Genomes
Match: AGB96409.1 (nuclear receptor binding SET domain protein, isoform B [Drosophila melanogaster])

HSP 1 Score: 60.8474 bits (146), Expect = 1.598e-8
Identity = 48/188 (25.53%), Postives = 84/188 (44.68%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRT---------KTHIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKF-----PKRKK--DFEPGKKFRNIFERAVKEAEAXMCIPVALRLEKLGFVYIPTNIDGATRNVLAKKKKSRRRSSKTSESENISSKFPLYQTVSRNDHQNIQGRQL 246
            G L W K+  + +WP +   DP   +   +    +R+         + H+ F A +  R W+   ++L++ G + F ++  +      PK  K     P +    I+ +A++EA+A   IP + RLEK    Y          NV+ K+K+++     TS+   + S   LY   S ++  N QG QL
Sbjct:  396 GDLFWGKVFSYCFWPCMVCPDPLGQIVGNMPSHPQRSSLDNANVPIQVHVRFFADNGRRNWIKPENLLTFAGLKAFDDMREELRIKHGPKSAKYRQMVPKRTKVVIWRQAIEEAQAMTQIPYSDRLEKFYQTY---------ENVVQKRKRTKYMMQDTSD---VGSS--LYD--STDNLHNKQGTQL 567          
BLAST of EMLSAG00000003515 vs. Select Arthropod Genomes
Match: AAF56762.2 (nuclear receptor binding SET domain protein, isoform A [Drosophila melanogaster])

HSP 1 Score: 59.6918 bits (143), Expect = 3.562e-8
Identity = 46/189 (24.34%), Postives = 84/189 (44.44%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRT---------KTHIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKF-----PKRKK--DFEPGKKFRNIFERAVKEAEAXMCIPVALRLEKLGFVYIPTNIDGATRNVLAKKKKSRRRSS-KTSESENISSKFPLYQTVSRNDHQNIQGRQL 246
            G L W K+  + +WP +   DP   +   +    +R+         + H+ F A +  R W+   ++L++ G + F ++  +      PK  K     P +    I+ +A++EA+A   IP + RLEK    Y          NV+   ++ R+R+     ++ ++ S   LY   S ++  N QG QL
Sbjct:  396 GDLFWGKVFSYCFWPCMVCPDPLGQIVGNMPSHPQRSSLDNANVPIQVHVRFFADNGRRNWIKPENLLTFAGLKAFDDMREELRIKHGPKSAKYRQMVPKRTKVVIWRQAIEEAQAMTQIPYSDRLEKFYQTY---------ENVVTLNRQKRKRTKYMMQDTSDVGSS--LYD--STDNLHNKQGTQL 571          
BLAST of EMLSAG00000003515 vs. Select Arthropod Genomes
Match: EEB16725.1 (set domain protein, putative [Pediculus humanus corporis])

HSP 1 Score: 57.7658 bits (138), Expect = 1.526e-7
Identity = 40/132 (30.30%), Postives = 63/132 (47.73%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPY---EGVTSKVIESSKRTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKFPK-----RKKD-------FEPGKKFRNIFERAVKEAEAXMCIPVALRLEKLGFVY 191
            G L+WA+  G  +WPG+   DP+   E    K +    R   H+ FLA    RAW  E  ++S+ G + F+++ +  P+     ++KD       F P K+    + RAVKE EA +C     R+  +   Y
Sbjct:  973 GDLVWARFAGNPFWPGLILRDPFNNDEYSKVKYLGRLPRPFVHVQFLADWGRRAWGPELYIMSFTGMDNFEKMKWDLPEVNTFTQRKDLLYQQAFFIP-KRMEKHWMRAVKEGEALLCKTKDERITYMKIKY 1103          
BLAST of EMLSAG00000003515 vs. nr
Match: gi|941757853|ref|XP_014331566.1| (PREDICTED: histone-lysine N-methyltransferase NSD3-like [Xiphophorus maculatus])

HSP 1 Score: 77.411 bits (189), Expect = 4.314e-11
Identity = 63/255 (24.71%), Postives = 112/255 (43.92%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIE--SSKRTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKEL-------AYKFPKRKKDFEP-GKKFRNIFERAVKEAEAXMCIPVALRLEKLGFVYI---PTNIDGATRNVLAKKKKSRRRSSKTSESENISSKFPLYQTVSRNDHQNIQGRQLPRRNPSHLIDTKSKDIYEFVDDETN--ASDSDLLSDYENTCDNTKDNLPKLGTLIWGHMAGFPYWPCFVT 314
            G L+W+K+  + +WP + + DP   V +++     S+  + H+ F      RAW++E  +++Y+G ++F EL       A    +R+K  +P  ++ R  +E  V  AE    +    R++   F+Y+   P +     +  L  +K+SRR S    + E++  K P        D +    RQLPRR  S + +T+     +  ++E N         S  +N   N K + P      W   A     P  +T
Sbjct:  379 GDLVWSKVGTYPWWPCMVSSDPQMKVHTRINTRGKSRHREYHVQFFGSVAERAWIHEKRIVTYQGKKQFDELQAETLRKATNPVERQKLLKPIPQRERTQWEVGVGHAEDAFLMTRQERIDNYTFIYVDPDPEDAPPTKKPSLRAEKRSRRSSGSVGKKEDVGVKLP--------DREQPPRRQLPRRQCS-ISNTEDSSNSQPAEEEKNQKGEQQKKSSPLQNAGSNAKQDSPPPVVRPWKTAAARKLLPLSIT 624          
BLAST of EMLSAG00000003515 vs. nr
Match: gi|934152399|gb|KPM03216.1| (histone-lysine N-methyltransferase Mes-4-like protein [Sarcoptes scabiei])

HSP 1 Score: 71.633 bits (174), Expect = 4.007e-9
Identity = 48/166 (28.92%), Postives = 85/166 (51.20%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKT--HIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKFPKRKKDFEPGKKFR---------NIFER---AVKEAEAXMCIPVALRLEKLGFVYIPTNIDGATRNVLAKKKKSRRRSSKTSESENISSK 226
            G L+WAK++G+ +WP + ++DP  G   ++  SS +     H+ +      R W N   V+ +EG+EK  E   K     KD +  K+ +         +I ++   ++ EAE  M +P+  R++ L F YI +N++  T     +  KS+  SS TS+S+ ++ K
Sbjct:  145 GDLIWAKMQGYPWWPCMISIDPETGTFCRIAGSSYKADRVYHVQYFGSQPYRGWTNIGMVMPFEGFEKLIE---KIQNEMKDLDRKKRSKIEAKYMVKNSILKKWNESISEAEEAMILPLKERVDLLTFNYI-SNVEKKT----PRPNKSKSDSSITSKSKTVTKK 302          
BLAST of EMLSAG00000003515 vs. nr
Match: gi|926636662|ref|XP_013784275.1| (PREDICTED: LOW QUALITY PROTEIN: histone-lysine N-methyltransferase NSD2-like [Limulus polyphemus])

HSP 1 Score: 70.4774 bits (171), Expect = 8.203e-9
Identity = 55/197 (27.92%), Postives = 90/197 (45.69%), Query Frame = 0
Query:   73 IEGCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKT-HIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKFPK--RKKDFEPGKKF----------RNIFERAVKEAEAXMCIPVALRLEKLGFVYI-------PTNIDGAT--RNVLAKKKKSRRRSSKTSESENISSKFPLYQTVSRNDH---QNIQGR 244
            I G LLW+KI G  +WP + + DP +G+ +KV+      +  H+ +  ++    W   S V++YEG +KF+E    F     KK+ +   K           +  +E AV+EAE  + +  A R ++L F Y+         +ID      + + K  K++  S+K S  E +  K P      +N       IQGR
Sbjct:  427 IIGDLLWSKISGHPWWPCMVSFDPIQGIYTKVVRVRTLARVYHVQYFGHEAQHGWTVPSCVMAYEGKDKFEEHVKNFIASVHKKNTKNRNKLLAKFKITPARKKAWELAVEEAEDALKMSRAERKQELTFQYVMPKPKKNSVDIDECKLENSHVTKNGKAKTHSNKCSPKEKLKQKTPKEGPAKKNKKVCSSKIQGR 623          
BLAST of EMLSAG00000003515 vs. nr
Match: gi|926620767|ref|XP_013775693.1| (PREDICTED: histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific-like [Limulus polyphemus])

HSP 1 Score: 68.9366 bits (167), Expect = 1.972e-8
Identity = 44/134 (32.84%), Postives = 68/134 (50.75%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKT-----HIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKF----PKRKKD-------FEPGKKFRNIFERAVKEAEAXMCIPVALRLEKLGFVYI 192
            G LLW+KI G  +WP + + DP +G  SKVI    R +T     H+ +  ++    W     VL+YEG +KF+E   KF    P+  K+       F+     +  +E AV+EAE  + +  A R ++L F Y+
Sbjct:  435 GDLLWSKISGHPWWPCMVSFDPIQGTYSKVI----RVRTLFRIYHVQYFGHEAHHGWTKPGCVLAYEGKDKFEEYVKKFVAAIPRGCKNRDKLLAKFKITSARKKAWELAVEEAEDALRMSRAERKQELTFQYV 564          
BLAST of EMLSAG00000003515 vs. nr
Match: gi|1048036438|ref|XP_017492378.1| (PREDICTED: histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific-like [Rhagoletis zephyria])

HSP 1 Score: 67.781 bits (164), Expect = 5.768e-8
Identity = 58/208 (27.88%), Postives = 92/208 (44.23%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKT--HIHFLAYDNLRAWVNESDVLSYEGYEKFKEL-------AYKFPKRKKDFE-----PGKKFRNIFERAVKEAEAXMCIPVALRLEKLGFVYIPTNIDGATRNVLAKKKKSRRRSSKTSESENISSKFPLYQTVSRNDHQNIQGRQLPRRNPSHLIDTKSKDIYEFVDD 268
            G L+WAK+ G+ +WP I ++DP  G   KV  SS +     H+ +   D  R W +   V+ +EG++KF E        A   P  +K  E     PG K +  +  +V EA+  M +    R++ L F Y      G   ++  KK  +  ++S      N +S  P   T  +    + +GR   R       +  S D+YEF +D
Sbjct:   71 GDLIWAKMTGYPWWPCIVSIDPVTGTYFKVTGSSYKADRVYHVQYFGPDPSRGWTSIGMVMPFEGFDKFSEKISNDIDNAANKPAAQKVLEKCTVKPGIKKK--WNESVAEAQEAMKLNRQERVQTLTFNYT-----GPGSDIKPKKVPTTPKASAV----NNNSATPKASTSGKKRSSSGKGRGSKR-------EATSDDVYEFPED 260          
BLAST of EMLSAG00000003515 vs. nr
Match: gi|1129896221|ref|XP_019742482.1| (PREDICTED: histone-lysine N-methyltransferase NSD3 isoform X4 [Hippocampus comes])

HSP 1 Score: 67.0106 bits (162), Expect = 9.729e-8
Identity = 51/189 (26.98%), Postives = 86/189 (45.50%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKEL-AYKFPKRKKDFEPGKKFRNIFER-------AVKEAEAXMCIPVALRLEKLGFVY---IPTNIDGATRNVLAKKKKSRRRSSKTSESENISSKFPLYQTVSRNDHQNIQGRQLPRRNPS 252
            G L+W+K+  + +WP + + DP   V +++     R + H+ F      RAW++E  ++ Y+G ++F EL A    K     E  K  + I +R        V  AE    +    R++   F+Y   +P     A + V   +K++RR S  T++ ++   K P  +   R        RQLPRR  S
Sbjct:  370 GDLVWSKVGTYPWWPCMVSSDPQMKVHTRINTRGHR-EYHVQFFGSVAERAWIHEKRIVIYQGKQQFDELQADTLRKTTNTVEKHKLLKPIPQRERAQWEVGVGHAEDAFLMTRQERIDNYTFIYVDPVPNETPIAKKPVGRPEKRNRRSSGSTTKKDDGGVKSPEREQPPR--------RQLPRRQCS 549          
BLAST of EMLSAG00000003515 vs. nr
Match: gi|1129896215|ref|XP_019742457.1| (PREDICTED: histone-lysine N-methyltransferase NSD3 isoform X1 [Hippocampus comes])

HSP 1 Score: 67.0106 bits (162), Expect = 9.959e-8
Identity = 51/189 (26.98%), Postives = 86/189 (45.50%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKEL-AYKFPKRKKDFEPGKKFRNIFER-------AVKEAEAXMCIPVALRLEKLGFVY---IPTNIDGATRNVLAKKKKSRRRSSKTSESENISSKFPLYQTVSRNDHQNIQGRQLPRRNPS 252
            G L+W+K+  + +WP + + DP   V +++     R + H+ F      RAW++E  ++ Y+G ++F EL A    K     E  K  + I +R        V  AE    +    R++   F+Y   +P     A + V   +K++RR S  T++ ++   K P  +   R        RQLPRR  S
Sbjct:  370 GDLVWSKVGTYPWWPCMVSSDPQMKVHTRINTRGHR-EYHVQFFGSVAERAWIHEKRIVIYQGKQQFDELQADTLRKTTNTVEKHKLLKPIPQRERAQWEVGVGHAEDAFLMTRQERIDNYTFIYVDPVPNETPIAKKPVGRPEKRNRRSSGSTTKKDDGGVKSPEREQPPR--------RQLPRRQCS 549          
BLAST of EMLSAG00000003515 vs. nr
Match: gi|1129896217|ref|XP_019742466.1| (PREDICTED: histone-lysine N-methyltransferase NSD3 isoform X2 [Hippocampus comes])

HSP 1 Score: 67.0106 bits (162), Expect = 1.022e-7
Identity = 51/189 (26.98%), Postives = 86/189 (45.50%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKEL-AYKFPKRKKDFEPGKKFRNIFER-------AVKEAEAXMCIPVALRLEKLGFVY---IPTNIDGATRNVLAKKKKSRRRSSKTSESENISSKFPLYQTVSRNDHQNIQGRQLPRRNPS 252
            G L+W+K+  + +WP + + DP   V +++     R + H+ F      RAW++E  ++ Y+G ++F EL A    K     E  K  + I +R        V  AE    +    R++   F+Y   +P     A + V   +K++RR S  T++ ++   K P  +   R        RQLPRR  S
Sbjct:  370 GDLVWSKVGTYPWWPCMVSSDPQMKVHTRINTRGHR-EYHVQFFGSVAERAWIHEKRIVIYQGKQQFDELQADTLRKTTNTVEKHKLLKPIPQRERAQWEVGVGHAEDAFLMTRQERIDNYTFIYVDPVPNETPIAKKPVGRPEKRNRRSSGSTTKKDDGGVKSPEREQPPR--------RQLPRRQCS 549          
BLAST of EMLSAG00000003515 vs. nr
Match: gi|1129896219|ref|XP_019742474.1| (PREDICTED: histone-lysine N-methyltransferase NSD3 isoform X3 [Hippocampus comes])

HSP 1 Score: 67.0106 bits (162), Expect = 1.043e-7
Identity = 51/189 (26.98%), Postives = 86/189 (45.50%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKEL-AYKFPKRKKDFEPGKKFRNIFER-------AVKEAEAXMCIPVALRLEKLGFVY---IPTNIDGATRNVLAKKKKSRRRSSKTSESENISSKFPLYQTVSRNDHQNIQGRQLPRRNPS 252
            G L+W+K+  + +WP + + DP   V +++     R + H+ F      RAW++E  ++ Y+G ++F EL A    K     E  K  + I +R        V  AE    +    R++   F+Y   +P     A + V   +K++RR S  T++ ++   K P  +   R        RQLPRR  S
Sbjct:  370 GDLVWSKVGTYPWWPCMVSSDPQMKVHTRINTRGHR-EYHVQFFGSVAERAWIHEKRIVIYQGKQQFDELQADTLRKTTNTVEKHKLLKPIPQRERAQWEVGVGHAEDAFLMTRQERIDNYTFIYVDPVPNETPIAKKPVGRPEKRNRRSSGSTTKKDDGGVKSPEREQPPR--------RQLPRRQCS 549          
BLAST of EMLSAG00000003515 vs. nr
Match: gi|26348305|dbj|BAC37792.1| (unnamed protein product, partial [Mus musculus])

HSP 1 Score: 65.4698 bits (158), Expect = 1.227e-7
Identity = 49/166 (29.52%), Postives = 83/166 (50.00%), Query Frame = 0
Query:   75 GCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRTKTHIHFLAYDNLRAWVNESDVLSYEGYEKFKELAYKFPKRKKDFEPGKKFRN---IFERA-----VKEAEAXMCIPVALRLEKLGFVYIPTNIDGAT----RNVLAK---KKKSRRRSSKTSESENISS 225
            G L+W+K+  + +WP + + DP   V SK+     R + H+ F +    RAWV+E  V  Y+G+E+++EL  +  K+  +    +K R      ERA     +  AE  + +    R+E+  F+YI    + A+    +NV +K   KK  R RS   S+ E  ++
Sbjct:   13 GDLVWSKVGTYPWWPCMVSSDPQLEVHSKINTRGAR-EYHVQFFSNQPERAWVHEKRVREYKGHEQYEELLAEAAKQASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERVEQYTFIYIDKQPEEASSQAKKNVTSKTEVKKPRRPRSVLNSQPEQTNA 177          
BLAST of EMLSAG00000003515 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold11_size778918-snap-gene-6.41 (protein:Tk03679 transcript:maker-scaffold11_size778918-snap-gene-6.41-mRNA-1 annotation:"histone-lysine n- h3 lysine-36 and h4 lysine-20 specific")

HSP 1 Score: 61.2326 bits (147), Expect = 9.368e-10
Identity = 50/177 (28.25%), Postives = 77/177 (43.50%), Query Frame = 0
Query:   74 EGCLLWAKIRGFSYWPGITTVDPYEGVTSKVIESSKRT----KTHIHFLAYDNLRAWVNESDVLSYEGYEKF-----------KELAYKFPKRKKDFEPGKKFRNIFERAVKEAEAXMCIPVALRLEKLGFVY-----IPTN--IDGATRNVLAKKKKSRRRSSKTSESENISSKFP 228
            EGC+LWA++ G  YWP     DP  G+ ++V  S +R     + H+ F      RAWV  + ++ YEG E+F           K    K P  K     GK  +  ++ AV+ AE  + +    R+ +L  V      +P      G++    A +K+ R  S  T  S     +FP
Sbjct:  549 EGCMLWARVGGAPYWPCAVINDPDLGIYTRV--SHRRGYVHREYHVQFFGKVIQRAWVVSNAIMEYEGIEEFLLKTEAVKNDLKGKKSKLPALKAYCIYGKVAKAAWDEAVEGAEKTLSLSSQERVLQLRNVTYDQPPVPRQRRTSGSSTISTASRKRKRNTSGGTVGSAVSEEEFP 723          

HSP 2 Score: 53.9138 bits (128), Expect = 1.627e-7
Identity = 40/123 (32.52%), Postives = 53/123 (43.09%), Query Frame = 0
Query:  296 GTLIWGHMAGFPYWPCFVTRSSD-GDYIREAKNKISV----HVQFFNWNDESGWVTKT--MPWCSVAEFRRFAKEAIKEDVSCSMDWSPV-------GKMLH-KWKNAALQAESTVHLSRKER 403
            G ++W  + G PYWPC V    D G Y R +  +  V    HVQFF    +  WV     M +  + EF     EA+K D+       P        GK+    W  A   AE T+ LS +ER
Sbjct:  550 GCMLWARVGGAPYWPCAVINDPDLGIYTRVSHRRGYVHREYHVQFFGKVIQRAWVVSNAIMEYEGIEEF-LLKTEAVKNDLKGKKSKLPALKAYCIYGKVAKAAWDEAVEGAEKTLSLSSQER 671          
The following BLAST results are available for this feature:
BLAST of EMLSAG00000003515 vs. GO
Analysis Date: 2014-04-02 (Blast vs. GO)
Total hits: 25
Match NameE-valueIdentityDescription
-1.768e-926.86symbol:WHSC1L1 "Uncharacterized protein" species:9... [more]
-2.227e-929.52symbol:Whsc1l1 "Wolf-Hirschhorn syndrome candidate... [more]
-5.948e-927.71symbol:Whsc1l1 "Wolf-Hirschhorn syndrome candidate... [more]
-1.478e-828.29symbol:WHSC1L1 "Uncharacterized protein" species:9... [more]
-1.869e-845.45symbol:MSH6 "DNA mismatch repair protein Msh6" spe... [more]
-2.837e-845.45symbol:Msh6 "mutS homolog 6 (E. coli)" species:100... [more]
-3.733e-828.47symbol:WHSC1L1 "WHSC1L1 protein" species:9606 "Hom... [more]
-3.771e-828.47symbol:WHSC1L1 "Histone-lysine N-methyltransferase... [more]
-4.286e-828.95symbol:WHSC1L1 "Uncharacterized protein" species:9... [more]
-5.681e-841.82symbol:MSH6 "Uncharacterized protein" species:9615... [more]

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BLAST of EMLSAG00000003515 vs. C. finmarchicus
Analysis Date: 2014-05-09 (TblastN vs C. finmarchicus TSA)
Total hits: 25
Match NameE-valueIdentityDescription
gi|592768106|gb|GAXK01186462.1|1.032e-2634.36TSA: Calanus finmarchicus comp45570_c1_seq1 transc... [more]
gi|592950526|gb|GAXK01008027.1|3.820e-831.62TSA: Calanus finmarchicus comp137877_c0_seq4 trans... [more]
gi|592950528|gb|GAXK01008025.1|3.855e-831.62TSA: Calanus finmarchicus comp137877_c0_seq2 trans... [more]
gi|592950527|gb|GAXK01008026.1|3.991e-831.62TSA: Calanus finmarchicus comp137877_c0_seq3 trans... [more]
gi|592950529|gb|GAXK01008024.1|4.028e-831.62TSA: Calanus finmarchicus comp137877_c0_seq1 trans... [more]
gi|592798956|gb|GAXK01155612.1|8.201e-525.00TSA: Calanus finmarchicus comp105552_c9_seq2 trans... [more]
gi|592798957|gb|GAXK01155611.1|8.202e-525.00TSA: Calanus finmarchicus comp105552_c9_seq1 trans... [more]
gi|592825260|gb|GAXK01129929.1|1.035e-425.42TSA: Calanus finmarchicus comp71342_c0_seq1 transc... [more]
gi|592875291|gb|GAXK01082286.1|1.089e-427.78TSA: Calanus finmarchicus comp112014_c8_seq11 tran... [more]
gi|592896801|gb|GAXK01061574.1|1.188e-434.29TSA: Calanus finmarchicus comp645744_c0_seq5 trans... [more]

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BLAST of EMLSAG00000003515 vs. L. salmonis peptides
Analysis Date: 2014-05-10 (Blastp vs. self)
Total hits: 1
Match NameE-valueIdentityDescription
EMLSAP000000035150.000e+0100.00pep:novel supercontig:LSalAtl2s:LSalAtl2s191:6249:... [more]
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BLAST of EMLSAG00000003515 vs. SwissProt
Analysis Date: 2017-02-10 (Blastp vs. SwissProt)
Total hits: 7
Match NameE-valueIdentityDescription
gi|118572948|sp|Q6P2L6.2|NSD3_MOUSE1.747e-929.52RecName: Full=Histone-lysine N-methyltransferase N... [more]
gi|68067672|sp|P52701.2|MSH6_HUMAN1.466e-845.45RecName: Full=DNA mismatch repair protein Msh6; Sh... [more]
gi|341940990|sp|P54276.3|MSH6_MOUSE2.225e-845.45RecName: Full=DNA mismatch repair protein Msh6; Al... [more]
gi|74761342|sp|Q9BZ95.1|NSD3_HUMAN2.958e-828.47RecName: Full=Histone-lysine N-methyltransferase N... [more]
gi|29427833|sp|Q8MT36.2|MES4_DROME7.349e-824.34RecName: Full=Probable histone-lysine N-methyltran... [more]
gi|118572947|sp|Q8BVE8.2|NSD2_MOUSE2.205e-725.98RecName: Full=Histone-lysine N-methyltransferase N... [more]
gi|74706096|sp|O96028.1|NSD2_HUMAN4.284e-726.77RecName: Full=Histone-lysine N-methyltransferase N... [more]
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BLAST of EMLSAG00000003515 vs. Select Arthropod Genomes
Analysis Date: 2017-02-20 (Blastp vs. Selected Arthropods)
Total hits: 5
Match NameE-valueIdentityDescription
gb|KPM03216.1|8.189e-1228.92histone-lysine N-methyltransferase Mes-4-like prot... [more]
gb|EEC05044.1|6.611e-927.82set domain protein, putative [Ixodes scapularis][more]
AGB96409.11.598e-825.53nuclear receptor binding SET domain protein, isofo... [more]
AAF56762.23.562e-824.34nuclear receptor binding SET domain protein, isofo... [more]
EEB16725.11.526e-730.30set domain protein, putative [Pediculus humanus co... [more]
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BLAST of EMLSAG00000003515 vs. nr
Analysis Date: 2017-02-20 (Blastp vs. NR (2/2017))
Total hits: 25
Match NameE-valueIdentityDescription
gi|941757853|ref|XP_014331566.1|4.314e-1124.71PREDICTED: histone-lysine N-methyltransferase NSD3... [more]
gi|934152399|gb|KPM03216.1|4.007e-928.92histone-lysine N-methyltransferase Mes-4-like prot... [more]
gi|926636662|ref|XP_013784275.1|8.203e-927.92PREDICTED: LOW QUALITY PROTEIN: histone-lysine N-m... [more]
gi|926620767|ref|XP_013775693.1|1.972e-832.84PREDICTED: histone-lysine N-methyltransferase, H3 ... [more]
gi|1048036438|ref|XP_017492378.1|5.768e-827.88PREDICTED: histone-lysine N-methyltransferase, H3 ... [more]
gi|1129896221|ref|XP_019742482.1|9.729e-826.98PREDICTED: histone-lysine N-methyltransferase NSD3... [more]
gi|1129896215|ref|XP_019742457.1|9.959e-826.98PREDICTED: histone-lysine N-methyltransferase NSD3... [more]
gi|1129896217|ref|XP_019742466.1|1.022e-726.98PREDICTED: histone-lysine N-methyltransferase NSD3... [more]
gi|1129896219|ref|XP_019742474.1|1.043e-726.98PREDICTED: histone-lysine N-methyltransferase NSD3... [more]
gi|26348305|dbj|BAC37792.1|1.227e-729.52unnamed protein product, partial [Mus musculus][more]

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BLAST of EMLSAG00000003515 vs. Tigriopus kingsejongenis genes
Analysis Date: 2018-04-18 (Blastp vs. Tigriopus kingsejongensis proteins)
Total hits: 1
Match NameE-valueIdentityDescription
maker-scaffold11_size778918-snap-gene-6.419.368e-1028.25protein:Tk03679 transcript:maker-scaffold11_size77... [more]
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Alignments
The following features are aligned
Aligned FeatureFeature TypeAlignment Location
LSalAtl2s191supercontigLSalAtl2s191:6249..9076 -
Analyses
This gene is derived from or has results from the following analyses
Analysis NameDate Performed
ensembl2013-09-26 .965016
Blast vs. GO2014-04-02
TblastN vs C. finmarchicus TSA2014-05-09
Blastp vs. self2014-05-10
Blastp vs. SwissProt2017-02-10
Blastp vs. Selected Arthropods2017-02-20
Blastp vs. NR (2/2017)2017-02-20
Blastp vs. Tigriopus kingsejongensis proteins2018-04-18
Properties
Property NameValue
Logic nameensemblgenomes
Descriptionmaker-LSalAtl2s191-augustus-gene-0.18
Biotypeprotein_coding
EvidenceIEA
NoteHistone-lysine N-methyltransferase NSD3
Cross References
External references for this gene
DatabaseAccession
Ensembl Metazoa (gene)EMLSAG00000003515 (primary cross-reference)
Relationships

The following mRNA feature(s) are a part of this gene:

Feature NameUnique NameSpeciesType
EMLSAT00000003515EMLSAT00000003515-699362Lepeophtheirus salmonismRNA


Sequences
The following sequences are available for this feature:

gene from alignment at LSalAtl2s191:6249..9076-

Legend: mRNA
Hold the cursor over a type above to highlight its positions in the sequence below.
>EMLSAG00000003515-686281 ID=EMLSAG00000003515-686281|Name=EMLSAG00000003515|organism=Lepeophtheirus salmonis|type=gene|length=2828bp|location=Sequence derived from alignment at LSalAtl2s191:6249..9076- (Lepeophtheirus salmonis)
ATGGCGACTGTCATATCAAGGTTTGTATTTGAACTTGATATAAAGAACTA GTATATGTACATTCAAAAAGGGAAGAATCAAATCATTAGCAAAAGAATCC TTTTGACATTGTCCTCCTTAATTTATCTAATGGATGAGGATTTCAACGTT AGATCCATTGTTTGCTAAATAGTTGATATCCAAGTGAGGAGGCCGATTGT TATGAATTATGAGCTTATTTCGTTATTCATCTATGTTCTGAGACAGATCT TCCATATTTTATTTATTGATCATCATTATGTATTACAAGTTACAAAGATT ATATTTTTATAATCAAATAACTAATCAGGGTTGTCATTGTATATATCTTA TTTTCATTAATTGTATCAAATAGAATAACACATCTTATAGTTTATCCAAT GATGTGAACATCATGATAATGACCTGTTCATTTCAAATTCATGACAGTGC ATTCAAAACTTTGGGTTGCAGTTCAAATTGGATACATTTTAATCACTTAT CGCGTTTTTTATAAATATATATTAATATATAGTTCTAAAAACGCTCATTT TTTTTTTTTTTCTAGGATCTAAAAAGKGATCACAAGAACTAACTTTAAAT ATCAAGCCCATGGATTTATAAATACCCATTGTTACAAGATAGAATATTTA TAAATAACTACCATTGAAGGTTTGTAAAAATGAGCTTATCAGAAGAAGAA CGACCTTCATTAACAGCAGAAGATTCAGATGACTCGGGAGTTCATTTAAA ACAATCAAGAATGTCGGACTGTGATCCGGATTCAGATGGTAGAACTCAGG GATGTGTTGAAATGGATTTTTCTCAGAAGATACACAAGTCATGTTCGCTG AGTGATCAAATGACTATAGAAGGTTGTCTTCTCTGGGCTAAAATTAGAGG GTTTTCTTATTGGCCTGGAATAACTACAGTTGATCCATACGAAGGAGTTA CGAGCAAAGTTATAGAATCATCCAAGCGTACGAAGACTCATATTCATTTC TTGGCATATGATAATCTACGCGCTTGGGTAAATGAATCGGATGTATTGTC CTATGAAGGTTATGAAAAGTTTAAGGAGCTTGCATATAAATTTCCAAAGA GGAAAAAGGATTTTGAGCCAGGGAAAAAGTTCCGTAATATTTTCGAACGG GCTGTTAAGGAAGCAGAGGCTGKTATGTGTATCCCTGTTGCATTGAGATT GGAAAAACTAGGATTTGTATATATTCCAACAAATATTGATGGGGCAACAC GAAATGTACTTGCTAAGAAAAAGAAAAGTAGGCGAAGGAGTAGTAAGACC TCCGAGTCTGAAAATATTAGCAGTAAGTTTCCTCTATACCAAACTGTATC TCGCAACGATCATCAAAATATTCAAGGTCGACAATTACCTCGAAGAAACC CATCTCATTTAATCGATACTAAATCCAAAGATATTTACGAATTTGTTGAT GATGAGACAAATGCTTCAGATTCTGATCTCTTGTCTGATTATGAAAATAC TTGTGATAATACCAAAGACAACTTGCCAAAACTTGGAACTTTAATATGGG GTCACATGGCTGGGTTCCCTTACTGGCCTTGTTTTGTGACTCGAAGTTCT GATGGGGATTACATAAGAGAGGCTAAAAACAAGATATCTGTGCATGTTCA ATTTTTCAATTGGAATGATGAGTCTGGTTGGGTAACTAAGACAATGCCTT GGTGCTCTGTGGCAGAATTTCGTAGATTTGCCAAAGAAGCCATTAAAGAG GATGTTAGTTGTTCAATGGATTGGAGCCCTGTTGGAAAGATGCTACATAA GTGGAAGAATGCTGCATTACAAGCTGAGTCAACCGTTCATTTATCTCGGA AGGAAAGGCATAAAAGATTCTTAGTTAAAATAAAGAAGAATATAGTAATG AATCGAAGAATAATTAATAATGGTTTCAGAGTGTCTGATGACCATATTAA TATCAATGCTTCAAAATCTCCCATTTCTAAGTTTAAAACMCCTCCCCCTC CCATTGTTACAACTTCTACTCGTTTACCTCCAGGTTGGATCATCCGTTGT TACAAAGAAGAAGACTATGGAAAGGAATCAAGAACTGAGTATCAGAGTCC AGATGGTGCGGTTTTCCTTAAAATTGAGAACGCTATATCGTATTTGTTCC AACAAAATAACTCTGGAATAAGAAAACGGTCCTACTCTACCCCTGGTGGT TGTATAGCATCTGATTATTCAAGTTTATCATGTCTTTCCCCCAGTCCTGC TTGTAAAAAACGTCGTTTAGATGCTGGATGGTTCATTTATGAGTCAGATC AACATAGATATTCTTCTMCMCTCCTCCGTCCACAAATTAATTATCTAGAT TTAGACGATTCTGTACANGTATATTCAAGATACTTCTCTTCCACGGGGTT GGTCAGTCAAACGCATTAGAATGGGAAGAAATCCTGAGGTGCAATCATCC TATTTATCACCAGAATGTAAAACATACTCGAAAGTTCCACAAGAATGGCC ATCACGAAGAGAGTTTTTCTCAAAAGCCGCAGCTGCCTCTTATCTCGAAG GAATGGGCCATCCAGCAGTTGAGCTTGAACATGTCATTGTTACAGGGATG ATCCAATGTCTCTCGCGTAAAGATCATTTTTTGAAAGTTGATGACTACTT GGATTATCGACTTTCAGAGACCCCTGAGCTGCGAAAAATTGTTGATCCAA CATTTGTAAAAGTGACTCCACTTCCAAAAGATATCTATAGACATTCAAGT GTTCTTGTTGAGGAGAAAGATGGAAAATTCCAATTGAAAGATGTTAATTC TGTTCCTCTTTCTTTAAATGGAAATTAA
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