Query:    8 SSVIVGGFERFFYWYGKLISRSPWLFLIGCLVGAGLCG--IGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQSWDDVCKRVPVIDLPGLGKQVQGPGNLRQSPCDDPSANDYDPSICLDS-------------------------------EIYCQVLDQSLSEACLETSILELFG----YEA--ETYDNLDEESILKKVNEDTPTSVVFKRPIDIGQLLSLTRDADGK-IIGARAASLSWLGQVDLEHISDGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYK-HKIEPAEKESEADYEYLS----QKVFR 523
            ++ IV G E +F W+G+ I + P +F+I CL  A L     G    R+E    KLW    +    N+E+L   FP D R+ NV++ A NVL PA +  MF++ + +S +    G +    C ++PV+  P     + G    R+   DD   +DY+ +   DS                               E YC ++D S+ E C E+S+LEL+G    YE+  +  ++L    IL  +N    + +   +      L  +TRD   K I+GA+A  + W  ++++       S   G GV VD  T+EFE ++ DI        +  G  I  ++++ + DIA  TI+GD  ++ +G++IVF YV++MLGKF+ V  R +L++ G+ S+   I+ + G+CSA G F+ PMH+++PFL+LGIGIDDMF+I+QC++ L P+E      ++  G TM+HAGVAITVTS+TD + F +G ++ LPALRSFC++  VGI A+Y+FQ TFFVA +  D +R++  RNG   C +  K++   +E   D E  S     K+FR
Sbjct:   49 TNCIVRGLESYFQWHGRFIGKHP-VFVI-CLCFAFLLASFAGFPYYRKEERRIKLWSSDKTPSRLNHEFLHEYFPSDFRFANVIVEADNVLDPAAIXAMFQMRKKISEIKTNYGDTLRTKCAKMPVVKTPNFLSFIFGKRRKRRV-ADDFFTSDYESNFFSDSFEHEMEEEEDNSGFDKDDISYPERLSVEAYPEPYCNIVD-SMEETCFESSVLELWGDNGEYESTEKRLESLSLIDILDTINNKNRSGIFLIKKNFTHMLGGITRDPITKEIVGAKATRMFWFLKMNIAEAR--KSPVEGQGVIVDKKTMEFEKEMLDIL--LNDTGLPEGLKISPHVSRSFFDIAGPTILGDVKILGIGYSIVFFYVLLMLGKFDWVGXRXYLAIAGIISVVFGIVFSIGICSAMGFFWSPMHSILPFLLLGIGIDDMFIIIQCWNTLNPYEKASSSVDKF-GYTMRHAGVAITVTSLTDIVAFGIGGTSXLPALRSFCIFSAVGIAAIYYFQVTFFVAWMVFDEKRISSGRNGCCPCIEVKKVKKNTEEIMEDMEVESLSIMSKIFR 600          

Query:   59 KLWVPSGSDFVANNEWLEANFPPDTRYN--NVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQSWDDVCKRVPVIDL-PGLGKQVQGPGNLRQSPCDD-------------PSANDYDPSI------------------CLDSEIYCQVLDQSLSEACLETSILELFGYEAETYDNLDEESILKKVNEDTPTSVV-FKRPIDIGQLLSLTRDADGKIIGARAASLSWLGQVDLEHISDGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPH-------EVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSST 450
            KLW+P  S+F++N +W+E NFP + R    ++L  + N+LTP  L  + +IH+ V  ++      W D+C +VPV ++     K +    N      DD              +  DYD +                    L  ++YC  + ++L++ C E S+LE++ ++      L ++ I++ +N    + V  +K   D   + S+ R+  G ++ A   +  W  QV+LE++S+       T   V+  +LE+E K  DIF +   A  EN +   I+ A+ ++DI  ++I  D   +  GF I+ +Y +IMLG+ NCVE R F ++ GL SI L ++V+ G+ SA GL Y P+  ++PFL LGIGIDDMF+I+QC+ N+          +   K  E M+  TMK AGV IT+TS+TD   F +G  T
Sbjct:   29 KLWIPQNSEFISNKKWIEENFPTNYRVQIISLLSLSGNILTPEALLLLLDIHEKVEQISAGHNTRWKDLCFKVPVANVFLERNKVLTNDKNTTFDRVDDLFISDDNVVPQNEKTEIDYDDAFLEYENESKNGSRYEKLLKILSPKVYCDFV-ETLNDRCFERSLLEIWKFDRRRIKRLTKDRIVQAINRIQNSPVYGYKTNYD-NYMGSIIRNETGHVVSASTLNSVWFTQVNLENVSEVI---GLTDEFVNKESLEWELKFVDIFLN---ASTENISAFGIS-ARSFNDITKKSIFFDGIRLTGGFFIMCIYTVIMLGRLNCVEVRFFATIAGLFSILLGMVVSLGIISAMGLKYSPVFAMLPFLYLGIGIDDMFIIVQCWYNILEQNKKECSTDQSIKTLEEMMAETMKDAGVTITITSLTDIFAFGIGGIT 453          

Query:   14 GFERFFYWYGKLISRSPWLFLIGCLVGAGLCG-IGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPD-----TRYNNVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQSWDDVC--KRVPVIDLPGLGKQVQGPGNLRQSPCDDPSANDYDPSICLDSEIYCQVLDQSLSEACLETSILELF-----GYEAETYDNLDEESILKKVNEDTPTSVVFKRPID--IGQLLSLTRDADGKIIGARAASLSWLGQVDLEHISDGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIG---DAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERM---IGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFC 498
            G    FY YG ++++  ++F IG  +G  +   +G ++   E++  K+W+P  S +V N + ++ +   D     T    ++ +  N+L    L  ++++H S+  +     +++ D+C  +RV V                   P   P            SEI C+ L  +    C   SI E++       EA     L +E IL  +++D   S +F+RP    IG   S   + +G + GA+A  LS+         S  ++S+   G+P+      +E  V +    F  +  +  +++ + +        AE   G   D  +   G+ IVFVY++  LG+ N +E + +L++VG+A +G+    + G+     ++  PM++++PF++LGIGIDDMFVI+Q   N++ ++ D +   +M   IG  MK AG AITVTS+TD L F +G  + LPALR+FCLY   GI  VYF+  TFF+    +D RR+  +R+  L C
Sbjct:   19 GINWIFYQYGMIVAKYSYVF-IGLSLGIFIASTLGFIDYVTESDPTKIWLPQDSYYVQNTKKIK-DLNSDAVNAATVIQVIVESEVNILRAKELNAVYKLHSSIINLKAPSNETFKDLCFKERVTV-------------------PISTPP-----------SEI-CRALANA-EWLCSAKSIFEIWTSDESSKEASIIAQLTDEDILDALSQDLAISKLFRRPFRPIIG---SKMFNDNGTLKGAKALLLSY---------SIKTNSSDKNGIPI------WEKSVKE--HVFNYSFGDESSNLSVTLFSS-SIFRAEFQNGMENDVQLFIFGYLIVFVYIIFNLGEMNTLEHKFYLAVVGIACVGMGYASSVGIFQLLSVYATPMNSILPFMLLGIGIDDMFVIVQASKNVKQND-DEEGENKMDSYIGNIMKSAGXAITVTSLTDILAFGIGGFSQLPALRNFCLYSSAGIFFVYFYIMTFFLGWFVIDARRVESHRDACLPC 468          

Query:  293 RPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYK-HKIEPAEKESEADY--EYLSQKVFRIVGQII 529
            R  + E+    LIN    + D    +I G  ++  VGF ++ +Y +++   F+ V  R  L L+G   IG+ I  ++GL    G+ Y  +H +IPFL+LGIG+DD+F+I++  DNL   E +    ER I L ++H+GV+ITVTS+TD + F++ S+TS+P LR+FCL   +GI  +YFF  TFF+A   LD RR+ + +  + F  + H + P +     +   +Y  + +F I  Q+I
Sbjct:   15 RDWVAEDWEKNLIN----FQDEIVTSIDGGMYVFGVGFLLILIYSLLVTSDFHPVNQRVMLLLLGFMVIGMAIGSSFGLGFHIGIIYADLHPIIPFLLLGIGVDDLFIIIKSTDNLSQKEKELPLKER-IALVVQHSGVSITVTSLTDLVAFLISSTTSIPLLRAFCLSVALGISFLYFFVVTFFIAWYTLDERRIEEGKAFLWFTKRVHSVPPKKSTWTHNLYKKYYVEYLFAIPSQLI 249          

Query:  241 IIGARAASLSWLGQVDLEHISDGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPAL---MENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYK 500
            IIG +A +LS+   V  E                D L L +E K  D  +   P     +E G  + ++    ++  A++  +     + V   +VF  V  ++   +  +++  +   GL S  +  +  +G     G+ +  ++   PFL+LGIG+DD FVI+  +   R    +    ERM G     A V+ITVTS+TDF  FM G  T  P +R FCLY G+ +  +YF+  T F A LA+  R    N +G +FC K
Sbjct:  206 IIGVKAVALSYFLDVSEEW--------------RDNLGLRWEKKFLDALREIGPYFAPDLEIG--MFVSNTPAWEMEASKNSVTSTLCINVVIMVVFSLVSCLMS--DATKSKPLVGFAGLFSATIATIAGFGFACYVGVEFISLNFAAPFLLLGIGVDDTFVILSSW---RRSSSNLSIPERM-GRCYSEAAVSITVTSLTDFFSFMAGVVTPFPCVRIFCLYTGISVAFIYFWHLTLFGAILAVSGRAEKNNLHG-MFCIK 445          

Query:  302 DILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLG-----KFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGP----MHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYK 500
            DI     +  +D  A+   GD   + V + I+F+Y+   LG     K   VE++  L L G+  + L++  + G+   FG    P    +  +IPFL+L +G D++F+++Q     R      + H   +G  +     ++ +TS+T+   F +G+ + +PA+R+F LY G+ ++  +  Q T F++ ++LD+ R N N   I+ C +
Sbjct:  571 DIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGI---FGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQ--RDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVR 773          

Query:  324 FMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGI 495
            F + +G  I F  +  M+   + V+++  L L G+ S  +  L ++G     G+ +  ++   PFLMLGIGIDD FV++  +     HE         +  T + A ++IT+TSITD L F +G  T  P++R FCLY G  +   Y +  TFF   +A+       NR+ +
Sbjct:  277 FALNIGIMIAFCIITCMMT--DWVKSKPLLGLFGVISAIMAXLFSFGFIIYCGVPFIGINLAAPFLMLGIGIDDTFVMLGSWRRTSVHETV----PARLAQTYRDAAISITITSITDMLSFWIGIITPFPSVRIFCLYTGACVAFTYLWHITFFGGCMAIAGYAEKSNRHSL 442          

Query:  312 DDIAAETIIGDAFMMPVGFTIVFVYVMIMLG-----KFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGP----MHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQN 491
            D+I+ ET  GD   + + + I+FVY+ + LG     K   +E++  L++ G+  + +++  + G+   FG    P    +  +IPFL+L  G D++F+++Q      P   +   H+  IG  +     ++ +TS T+   F +G+ + +PA+R+F LY G+ ++  +F Q T F++ +ALD+ R  +N
Sbjct:  433 DEISKETT-GDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGI---FGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTE--THQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQREN 615          

Query:  321 GDAFMMPVGFTIVFVYVMIMLGKFNCVETRAF---LSLVGLASIGLTILVTYGLCSAFGLFYGPM-HNVIPFLMLGIGIDDMFV-IMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCY--KHKIEPAEKESEADYEYLSQKVF-RIVGQIITKPL 533
            GD  ++ + + ++FVYV   L  F     + F   L++ G+  +  +IL T GL    G+    +   ++PFL+L +GID++FV ++     L   E    + + +IG+T++    A+ ++++T    F +G+ + +PA+ +F LY G  ++  +  Q T F+A L+LDL+R+   +  +  C   K +I+    +S  +Y+      F + V  ++ K L
Sbjct:  403 GDVLVVIISYFLMFVYVSFALTDFR--NKKYFGITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKL 621          

Query:    1 MKFLDKVSSVIVGGFERFFYWYGKLISRSPWLFLIGCLVGAGLC---GIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPNVLT 97
            +KFLDK+S++     E  FY  G  ++  PW  +   LV + +C     GL+   + T+   LW P  ++ + N  W+E N+P D+R   ++L APNVLT
Sbjct:    2 VKFLDKLSTLFTRTLENIFYRLGFTVATYPWWTI---LVSSIICLSTMTGLIWFHQTTDYEVLWAPDNTNALQNKLWIEKNYPKDSRLEYIILEAPNVLT 98          

Query:   14 GFERFFYWYGKLISRSPWLFLIGCLVGAGLCGIGLMEL-REETNAFKLWVPSGSDFVANNEWLEANFP-------------PDTRYNNVLLT--APNVLTPAILKQMFEIHQSVSTVNLTDGQS----WDDVCKRVPVIDLPGLGKQVQGPGNLRQSPCDDPSANDYDPSICLDSEIYCQVLDQSLSEACLETSILELFGYEAETYDNLDEESILKKVNEDTPTSVVFKRPIDIGQLLSLTRDADGKIIGARAASLSWLGQVDLEHISDGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILI--NIAKGYD-DIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRR 487
            GF+RF    G  +  +PWLFL+G  +     G GL+ L +E+ N  + + P GS   A   +++ +F               +T + ++L+   A ++L P I K++ ++ Q+V  + +         + +VC +   + +P        P  L                                           LF ++  +  NL +   L     +TPT +++      G +L        +++ +RA  L  L  +  E   D   S A            +     D F   + +L     +++   ++++  + +  ++T+I    +  + + ++ ++ ++   + +C+  +  +++ G+ S+ ++++  +GL    G+ +  +    PFL+LG+G+DDMF+++  +      E      ER+   +     V+IT+T+IT+ L F  G ++S  +++ FC+Y G  ++  YF+  T F A +ALD +R
Sbjct:   83 GFQRF----GATVGANPWLFLLGPALLTASLGTGLIFLPKEKENLEEQYTPIGSPAKAERRFVQGHFSTNDTYRFSASRTSSETNFASILVVSLANSLLEPEIFKEVSKLDQAVQALKVVQENGTQILYQEVCAKYKTLCVP--------PNPL-------------------------------------------LFSWQHNSSLNLSD---LTFPIHNTPTQLIYLAGFFGGNVLGQMTGKSQRLVESRAMRL--LYYLKTEDPEDSERSQA------------WLTHFLDHFNDMKSSLTLEEIEVVYFSSLSRQLEFEATSKTVIP---LFHLAYILIILFAVVSCSRLDCIRNKMCVAVFGVFSVAMSVVSGFGLMLHLGVPFVIIVANSPFLILGVGVDDMFIMISAWQKTSLSE---SIRERLSN-SYSKVAVSITITTITNVLAFYTGITSSFRSVQYFCIYTGTTLLFCYFYSITCFGAVMALDGKR 500          

Query:   15 FERFFYWYGKLISRSPWLFLIGCLVGAGLCGIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLL------TAPNVLTPAILKQMFEIHQSVSTVNLT-DGQSWD--DVC------------------KRVPVIDLPGL-----GKQVQGPGNLRQSPCDDPSANDYDPSICLDS-------EIYCQVLDQS------LSEACLETSILELFGYEAETYDNLDEESILKKVNEDTPT-SVVFKRPIDIGQLLSLTRDADGKIIGARAASLSWL---GQVDLEHI-SDGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGAD--------ILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGL-FYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYK 500
            F+   +  G  I R     L   L+  G   +GL     ETN  +LWV  GS       + +     +  Y + +L         N+LTP  L    +   + S V ++  G+SWD   +C                  K  P + L  L     G ++QG G+       D    + DP   L+        E + ++LD++      +   CL    L      A  + +    ++  +++      S  F    +   L  + RD  G+++ A A   ++L    +   EH   D  + + G      +  L+   + F   Q  + AL EN +          L +I   + +++A  ++G       G+ ++  Y  + + +++C +++  + L G+  + L +    GLC+  G+ F      V+PFL LGIG+DD+F++   F    P        ERM G  ++  G ++ +TSI +   F++ +   +PALR+F L   + +   +      F A L+LDLRR +  R  +L C+ 
Sbjct:   40 FQGLLFSLGCGIQRHCGKVLFLGLLAFGALALGLRMAIIETNLEQLWVEVGSRVSQELHYTKEKLGEEAAYTSQMLIQTARQEGENILTPEALGLHLQAALTASKVQVSLYGKSWDLNKICYKSGVPLIENGMIERMIEKLFPCVILTPLDCFWEGAKLQG-GSAYLPGRPDIQWTNLDPEQLLEELGPFASLEGFRELLDKAQVGQAYVGRPCLHPDDLHC-PPSAPNHHSRQAPNVAHELSGGCHGFSHKFMHWQEELLLGGMARDPQGELLRAEALQSTFLLMSPRQLYEHFRGDYQTHDIGWSEEQASTVLQAWQRRF--VQLAQEALPENASQQIHAFSSTTLDDILHAFSEVSAARVVG-------GYLLMLAYACVTMLRWDCAQSQGSVGLAGVLLVALAVASGLGLCALLGITFNAATTQVLPFLALGIGVDDVFLLAHAFTEALP---GTPLQERM-GECLQRTGTSVVLTSINNMAAFLMAALVPIPALRAFSLQAAIVVGCTFVAVMLVFPAILSLDLRRRHCQRLDVLCCFS 569          

Query:  304 LINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGL-FYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYK 500
            L +I + + +++   ++G       G+ ++  Y  + + +++C +++  + L G+  + L +    GLC+  G+ F      V+PFL LGIG+DD+F++   F    P   D    ERM G  ++  G ++ +TS+ + + F + +   +PALR+F L   + +   +      F A L+LDLRR ++ R  +L C+ 
Sbjct:  383 LDDILRAFSEVSTTRVVG-------GYLLMLAYACVTMLRWDCAQSQGAVGLAGVLLVALAVASGLGLCALLGITFNAATTQVLPFLALGIGVDDIFLLAHAFTKAPP---DTPLPERM-GECLRSTGTSVALTSVNNMVAFFMAALVPIPALRAFSLQAAIVVGCNFAAVMLVFPAILSLDLRRRHRQRLDVLCCFS 569          

Query:  281 FEDKVFDIFQSFRPALMENGAD---ILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFN-----CVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYG-PMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYKHKIEPAEKESE 511
            +E+      +SF+     N +D   +  +  +  +D    T I D  +  V + IVF+Y+ + LG ++      VE++A L L G+  +   +L   G  S  G+     +  V+PFL+L +G D++F+ +  +  L    +  +  E  IG T+     ++ + S+++ + F +G+ T +PA+R+F L  G+ II  +  Q T FVA L+LD +R   +R  +L C+  +  P  KE E
Sbjct:  592 WEEAFLKEMESFQ----RNTSDKFQVAFSAERSLEDEINRTTIQDLPVFAVSYIIVFLYISLALGSYSRCSRVAVESKATLGLGGVIVVLGAVLAAMGFYSYLGVPSSLVIIQVVPFLVLAVGADNIFIFVLEYQRL--PRMPGEQREAHIGRTLGSVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAIILDFLLQMTAFVALLSLDSKRQEASRPDVLCCFSTRKLPPPKEKE 825          

Query:   15 FERFFYW----YGKLISRSPWLFLIGCLVGAGLCGIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPN-----------VLT--PAI----LKQMFEIHQSVSTVNLTDGQSWDDVCKRVPVI---DLPGLGK-QVQGPGNLRQSPCDDPSANDYDPSICLDSEIYC-QVLDQSLSEACLETSILE-LFGYEAETYDNLDEESILKKVNEDTPTSVVFKRPID----IGQLLSLTRDADGKIIGARAASLSWLGQVDLEHISDGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFL--SLVGLASIGLTILVTYGLCSAFGLFYGPMH--------NVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYK 500
            F  FFY     +G   ++ P + L  C         G+  +   T+  +LW    S      ++ + +F P  R N + + A N           VL   PA     LK++FE+  S+  + + D +  D +C   PV+   + P + +  +Q      Q   D    N Y     +DS  Y    L+Q   E CL   ++E  FG                           F  PI+    +G +  +    D   + A    L++LG+    + +D S              LE   K   +F  F      +  DI     +   D   E   G+   + + + ++FVYV I LG       R FL  S + LA  G+ I++   +CS  G F+G +          VIPFL+L +G+D++F+++  +  L   +  FK     IG  +   G +I  T+ ++   F +G  + +PA+++F +Y  + I+  +  Q T FVA +A+D +R    R  +L C K
Sbjct:  306 FGEFFYHGFRIWGTFCAKHPVIVLALCSWAIAGLSFGIRYMTITTDPVELWAGEESQTRIEKDYFDQHFGPFYRTNQMFVKAVNQTYFTHETSNGVLNFGPAFEYNFLKEVFELQDSIMKLGMADNEGLDKIC-YAPVLMAGETPTVDRCAIQSVYGYFQHDMDR-FENSY-----VDSNNYTINYLNQL--EDCLRVPMMEDCFG--------------------------TFGGPIEPGIAVGGMPKVAVGEDPDYMLATGLVLTFLGR----NYNDESK-------------LEPNMKWEKLFVDFLRDYKSDRLDIAYMAERSIQDAIVELSEGEVSTVVISYVVMFVYVAIALGHIR--SCRGFLRESRIMLAIGGIVIVLASVVCS-LG-FWGYLDVTTTMLAIEVIPFLVLAVGVDNIFIMVHTYQRLDHSK--FKTTHEAIGEAIGQVGPSILQTAGSEMACFAIGCISDMPAVKTFAMYAAIAILLDFLLQITAFVALMAIDEKRYLDGRLDMLCCVK 774          

Query:    5 DKVSSVIVGGFERFFYWYGKLISRSPWLFLIGCLVGAGLCGIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQSWDDVCKRVPVIDLPGLGKQVQGPGNLRQSPCDDPSANDYDPSICLDSEIYCQVLDQSLSEACLETSILELFGYEAETYDNLDEESILKKVNEDTPTSVVFKRPIDIGQLLSLTRDADGKIIGARAASLSWLGQVDLEHISDGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDD------IAAETII---------GDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCS--AFGLFYGPMH----NVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYK 500
            D VS+   G   R F  +G    R+P   +   LV    C  GL+ +R  TN   LW    S      E+ + +F P  R   +++ A     P   K +++ + S + V               P +D+  L + +       Q   ++ +A+ YD       +I C       +  C   S+L  F       D+   +      +  T      + P  +    SL  D      G        LG  D     D + +NA   V    +T    +   D  +  R    E      IN  K Y +        AE  I          D F + + + I+F+Y+ + LG           S V L   G+ I+++   CS   F     P+      VIPFL+L +G+D++F+++Q +   R   +  +  ++ +G  +     ++ ++S ++ + F +G+ + +PA+ +F L+ G+ +   +  Q T FV+ L LD++R  +NR  I  C +
Sbjct:  325 DPVSAAFEGCLRRLFTRWGSFCVRNPGCVIFFSLVFITACSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIRA-----PLTDKHIYQPYPSGADVPFG------------PPLDIQILHQVLD-----LQIAIENITAS-YDNETVTLQDI-CLAPLSPYNTNCTILSVLNYFQNSHSVLDHKKGDDFFVYADYHTHFLYCVRAPASLNDT-SLLHDPCLGTFGGPVFPWLVLGGYD-----DQNYNNATALV----ITFPVNNYYNDTEKLQRAQAWEKE---FINFVKNYKNPNLTISFTAERSIEDELNRESDSDVFTVVISYAIMFLYISLALGHMKSCRRLLVDSKVSLGIAGILIVLSSVACSLGVFSYIGLPLTLIVIEVIPFLVLAVGVDNIFILVQAYQ--RDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLGALSVMPAVHTFSLFAGLAVFIDFLLQITCFVSLLGLDIKRQEKNRLDIFCCVR 802          

Query:  280 EFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFM---MPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYK----HKIEPAEKESEADYEYL-SQKVFRIVGQIITK 531
            E  ++  D+F S  P   E  + I  + +K    +A E       +   MP    ++ V+ M      N V+++ F+    + +  +  + +  L       + P+  ++PFL++ IG D+MF++++ +   R  +    + +R I   +  +  ++ +TS+TD L F +GS +   A+R FC YC + I+ ++ FQ TFF A ++L  RR    ++ +  CY+     + +  EK+S  D+  + ++ +F+I+  + ++
Sbjct:  222 ESTERWIDLFLSAIPRYKETNSTIFWSSSKS---LAKEMERNGELLIPWMPWTSLVLVVFCMFACSSLNIVKSQPFIGFFAMFNATMATIASTSLLLYLQYPFLPLVFIMPFLVVSIGTDNMFLMLKSW---RMTKKSSNEEQRYIH-ALTESAASLFLTSLTDGLSFAIGSISDFHAVRVFCTYCAMAILFMFLFQVTFFNAVMSLCCRREVSGKHPVFCCYEITPPEETQVLEKQSNFDFSSIVAKHLFKILNPLPSR 474          

Query:  304 LINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGL-FYGPMHNVIPFLMLGIGIDDMFVIMQCFDNL-RPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCY 499
            L +I K + D++   +         G+ ++  Y  + + +++C +++  + L G+  + L++    GLCS  G+ F      V+PFL LG+G+DD+F++   F    +   + F+D     G  +K  G ++ +TSI++   F + +   +PALR+F L   V ++  +      F A L++DL R    R  I  C+
Sbjct:  427 LDDILKSFSDVSVIRVAS-------GYLLMLAYACLTMLRWDCAKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDR---TGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCF 614          

Query:  304 LINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGL-FYGPMHNVIPFLMLGIGIDDMFVIMQCFDNL-RPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYKH-------KIEP-AEKESEADYEY 516
            L +I K + D++   +         G+ ++  Y  + + +++C +++  + L G+  + L++    GLCS  G+ F      V+PFL LG+G+DD+F++   F    +   + F+D     G  +K  G ++ +TSI++   F + +   +PALR+F L   V ++  +      F A L++DL R    R  I  C+         ++EP A  E  ++  Y
Sbjct:  413 LDDILKSFSDVSVIRVAS-------GYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDR---TGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTEPHSNTRY 625          

Query:  304 LINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGL-FYGPMHNVIPFLMLGIGIDDMFVIMQCFDNL-RPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCY 499
            L +I K + D++   +         G+ ++  Y  + + +++C +++  + L G+  + L++    GLCS  G+ F      V+PFL LG+G+DD+F++   F    +   + F+D     G  +K  G ++ +TSI++   F + +   +PALR+F L   V ++  +      F A L++DL R    R  I  C+
Sbjct:  427 LDDILKSFSDVSVIRVAS-------GYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDR---TGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCF 614          

Query:    4 LDKVSSVIVGGFERFFYWYGKLISRSPWLFLIGCLVGAGLCGIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAP--NVLTPAILKQMFEIHQSVSTVNLTDGQ-SWDDVCKRVPVIDLPGLGKQVQGPGNLRQSPCDDPSANDYDPSICLDSEIYCQVLDQSLSEACLETSILELFGYEAETYDNLDEESILKKVNEDTPTSVVFKRPIDIGQLL--SLTRDADGKIIGARAASLSWLGQVDLEHISDGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYKHKIEPAEKESEADYEYLSQKVFRIVGQII 529
            L  +S  +V G E FF WYG  ++R P++ ++ CLV  G   IG+++ R E NAFKLW+P  SDFVA+N WLE N PP+ R+N++++T+P  +VL P ++K + ++   V+     + +  W   C +    D+P    Q   P          P A              C  +   L   C E SILE +  + + ++ LD+ S+L+++N D   S  FK PI+I   L   + RD  GKI+ A A  + W G+++   ++    S++GTG  VD+ +LE+E+++  + +  +  L  N  +  IN+A+ Y D+A ETI+ DA MMP+GF IVFVYV IMLGKF C E RA L+L GLA IGLT+  TYG CSA  LFYGPMHNVIPFL+LGIGIDDMFVIMQC+DNL P + D  + +  IG+TM+HAGVAITVTS+TDF+VF +G +T LPAL+SFCL+C VGIIAVYFFQAT F A L LD RRL  NRNG+  CY HK +  + +       LSQK F+   + I
Sbjct:    5 LTAISEKVVHGLEDFFSWYGIKVARHPFIAILACLVITGAAAIGMIKYRTENNAFKLWIPDNSDFVADNAWLEENSPPEIRFNSLIVTSPGGSVLNPELIKHLNKLRLKVNEFETDENKLDWKQQCFQR---DVPKFAVQQDIPY---------PEA--------------CPGIASMLEPVCFEQSILEFWPKDYD-FEKLDQTSLLEQINADNAFSSFFKTPINIVDYLGGKIERDPTGKIVSAEATFMRWYGKINSTAVTPDDISSSGTGEIVDSNSLEWEEQLEKVLKDDQSELPAN-IETFINVARSYSDVAGETIVNDAMMMPIGFLIVFVYVTIMLGKFTCTEQRALLALGGLACIGLTVGFTYGFCSALDLFYGPMHNVIPFLLLGIGIDDMFVIMQCYDNLGPLKTD--NIQENIGMTMRHAGVAITVTSLTDFIVFALGGTTVLPALKSFCLWCSVGIIAVYFFQATLFTAFLTLDCRRLASNRNGLCPCYTHKKKKEKVDITKIDLSLSQKCFQHFSKFI 505          

Query:    1 MKFLDKVSSVIVGGFERFFYWYGKLISRSPWLFLIGCLVGAGLCGIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQSWDDVCKRVPVIDLPGLGKQVQGPGNLRQSPC-------------------DDPSANDYDPSICLDSEIYCQVLDQSLSEACLETSILELFGYEAETYDNLDEESILKKVNEDTPTSV---VFKRPIDIG-QLLSLTRDADGKIIGARAASLSWLGQVDLEHISDGSSSN-AGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGIL 496
            M  L  +S  IVG  ERFFY +G  I  +P  F++ C++   LCGIGL+    E    KLW+P  S+FV + EWL  NFP   R++  ++TA +VL P +L  + EIH  V  +  +  + W D+C ++PVI      ++ +   N   S                     +  S   +DPS+ L +++YC ++  SL + C E ++LEL+ Y +   + L +E I+  +N +    V   VF RP++   +L  L R+  G IIGA A  + W  +++   ++ G   N  GTG  VD     +E ++   F SFRP     G +I  N+A+ + DI+  TI+GDA M+ VGF+IVF+YV+ MLGKFN VE R  LSL GL+ +GL ILV+YG+CSAF + YGP+HN++PFL+LGIGIDDMFVIMQC++NLRP ++  K     +GLT++HAGV+IT+TS+TDF  F +G +T LPAL+SFC+Y  +GI+A Y FQATFFVA LA+D +R+ + RN  +
Sbjct:   53 MTILQLISLKIVGSLERFFYRWGYQIGLTPVPFIVACVILTVLCGIGLLRFTPENRPDKLWIPWNSEFVKDTEWLNKNFPSPFRFHYAIITAEDVLQPKVLDVLLEIHNKVKEIEASTYK-WKDICFKLPVIKFDTNKRRKREVNNANNSATLFNGNFDGFDSAFDFDDDEEATSEKPFDPSVSLPTDVYCNIVS-SLDKECFELNMLELWNYNSSVINKLTKEEIVNAINHEQIRQVFYPVFGRPVNYATELGKLQRNESGYIIGAEAVMIRWFARLNRTAMNLGDVLNDEGTGQAVDKYNFMWEKELSKFFLSFRPP---EGVNIYFNVARSFADISGSTIMGDASMLAVGFSIVFLYVIFMLGKFNFVEQRPLLSLAGLSCVGLAILVSYGICSAFKIIYGPVHNILPFLLLGIGIDDMFVIMQCWNNLRPEDMK-KSIPEKLGLTLQHAGVSITITSLTDFFAFAIGGTTVLPALQSFCVYAALGIVATYIFQATFFVAWLAIDQKRIERRRNAFI 566          

Query:    7 VSSVIVGGFERFFYWYGKLISRSPWLFLIGCLVGAGLCGIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQSWDDVCKRVPVIDL------------------------PGLGKQVQGPGN-----------LRQSPCDDPS-------------ANDYDPSICLDSEIYCQVLDQSLSEACLETSILELFG---YEAETYD---NLDEESILKKVNEDTPTSVVFKRPIDIGQLL-SLTRDADGKIIGARAASLSWLGQVDLEHISDGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPH-EVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYKHKIEPAEKESEADYEYLSQKVFRIVGQIITKPLVKG 536
            +S  IV   E FFYWYG +++R P   +   LV  GLC IGL+ L +E N +KLW+P  SD++ N+EWL  NFP D R+++V+LT  NVLTP  +++++E+H+++  V  + G+ W D+C RVP++DL                        P   +Q+Q  G+            + S  D+ +             A+++DP+I L  E YC +++   +  CLE S+LEL+G   Y  ET D    L +E IL+ +N  T TS V+ R  D  + L  ++R++ G IIGARA  L + GQV+   ++D        G PVD  TL +ED + D+       L +  + ++ N+AK + D++A  I GDA +  +G + VFVYV IMLGKFN V+TR  LS VGL   GL IL +YG CS  GL + P+H+VIPFL++G+G+DDMFVIMQ  DNL           ER I  TMK  GVAIT+TS TD + F +G+ T LPAL+SFCL+C VGI +VYF+ AT FVA L++D RR+   RNG+     HK     K S+ ++    +++F  +G +++ P V+ 
Sbjct:   27 ISETIVHSMELFFYWYGSILARYPIRSICLTLVIPGLCAIGLLRLEQENNPYKLWIPQDSDYIRNHEWLWQNFPDDIRFHSVILTGDNVLTPEYIRKLYEVHEAMVNVTSSKGERWSDICYRVPMVDLEPIQDLLNDSLYEYEDYEDDVEEIPETTEQIQDGGSETTADSMFDITTQISVIDNSTLISSNNSENRIKRASEFDPAIDLYPEDYCPLIEDLTTSICLENSLLELWGKAGYTQETKDIIYALTQEDILRAINTVT-TSPVYDRAQDFSKYLGDISRNSSGHIIGARAMFLRFFGQVNTTALTDSEDVAVTKGSPVDGNTLAWEDAIIDVLSK----LADGDSSLVFNVAKSFSDLSAGAIYGDALLFGIGTSTVFVYVQIMLGKFNFVQTRPGLSSVGLGCYGLAILTSYGFCSGIGLVFSPLHSVIPFLIMGLGVDDMFVIMQSLDNLDAKGGTALWSIERKIAETMKLGGVAITITSFTDLIAFAIGAITVLPALKSFCLFCAVGIASVYFYTATIFVAFLSIDERRIRAKRNGMCPLIVHKDWTPNKISQREF---GRELFEKLGWVLSNPFVQA 604          

Query:    4 LDKVSSVIVGGFERFFYWYGKLISRSPWLFLIGCLVGAGLCGIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQSWDDVCKRVPVIDLPGLGKQVQGPGNLRQSPCDD----------------PSAN---DYDPSICLDSEIYCQVLDQSLSEACLETSILELFGYEAETYDNLDEESILKKVNEDTPTSVVFKRPIDIGQLLSLTR-DADGKIIGARAASLSWLGQVDLEHIS-DGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYKHK 502
            +++ S + +  FE FF  +G  ++++PW ++I  +V A  C IGL+    E    KLW+P  S FV N+EWL+ NFP + R  + ++   NVL P +L  M E+H +++ V+   G  W DVC +VPV+      ++ +   N+ ++   D                PS++   D++P+I L + I+C ++ + L EACLE +IL+++ Y+ E    L  E I+  +N    +++     +    LL   R +  G I+ A +  +    +V+   I+ D + ++AGTG  VD + LE+E    ++  +F      N + +    A+ + DI++ TI+GD  ++  G  +VF+YV +MLGKFN VE RAFLSL G+AS+ + I+V+YGLCSAFG+FYGP+H+++PFL+LGIGIDDMFVI+QC+ NL   E+  +     IG+TMKHAGV+IT+TS+TDF  F VG++T LP+LRSFC+Y  VGI+A Y FQA+FFVA L LD +R+  +R+G++ C+ H+
Sbjct:   23 VNRASFIFMANFENFFLRWGITVAKNPWTYIIASVVIAATCSIGLLNFTAENRPTKLWIPQDSGFVQNSEWLQENFPNEIRLQSWVVVDDNVLRPEVLLWMLELHDNITAVSSASGYQWRDVCFKVPVVTEQQTNQRRKRQLNISENDPFDFEDFNFDGFDANFEEMPSSSIDPDFEPAIDLPTGIFCDIV-EGLEEACLENNILDIWSYKKEVISKLSREDIINTINTVQKSNLT---RVQYSSLLGQPRFNETGHIVSAGSLLVQLFSRVNYSLIANDVTDNDAGTGEVVDPINLEWEKAFVNLLHNFTSP--PNSSKLYYMAARSFGDISSATILGDVRLLAAGICVVFIYVQLMLGKFNLVEQRAFLSLTGIASVAMAIVVSYGLCSAFGVFYGPVHSILPFLLLGIGIDDMFVIVQCWSNLNKEEMK-RSLPVRIGITMKHAGVSITITSVTDFAAFAVGATTVLPSLRSFCIYSAVGILATYIFQASFFVAWLTLDQKRIESHRDGMIPCFVHR 535          

Query:   22 YGKLISRSPWLFLIGCLVGAGLCGIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQSWDDVCKRVPVIDLPGLGKQVQGPGNLRQ----------------------SPCDDPSANDYDPSICLDSEIYCQVLDQSLSEACLETSILELFGYEAETYDNLDEESILKKVNEDTPTSVVFKRPIDIGQLLSLTR-DADGKIIGARAASLSWLGQVDLEHIS-DGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYKHK 502
            +G  ++++PW ++I  +V A  C IGL+    E    KLW+P  S FV N+EWL+ +FP + R  + +L   +VL P     M E+H +++ +  ++G  W DVC ++PV+  P   ++ +   N  +                      +P  DP   +++P+I L   I+C ++ + L EACLE + L+++ Y+ E    L  + I+  +N    +++     +    L+   R +  G I+GA +  +  L +V+   I+ D +S++AGTG  VD ++LE+E    ++  +F   L  N +++    ++ + DI++ TI+GD  ++  G  +VF+YV +MLGKFN VE RAFLSL G+AS+ + ILV+YGLCSAFG+FYGP+H+++PFL+LGIGIDDMFVI+QC+ NL   E+  +     IG+TMKHAGV+IT+TS+TDF  F VG++T LP+LRSFC+Y  VGI+A Y FQA+FFVA L LD RR+  +R+G+L C+ H+
Sbjct:   66 WGITVAKNPWTYIIASVVIAATCSIGLLNFTAENRPTKLWIPQDSGFVHNSEWLQEHFPNEIRLQSWVLVDDDVLRPETFLWMLELHDNITELASSNGYKWKDVCFKIPVVTEPETKRRRKRQANSSEIESFGFEDFDFDGFDSNFEDIPAPALDP---NFEPAIDLPIGIFCDIV-EGLEEACLENNFLDIWNYKKEVISKLSRQDIINAINSVERSNLT---RVQYSNLIGQPRYNESGHIVGAGSVLVQLLTRVNYSLITNDATSNDAGTGDLVDPISLEWEGAFVNLLHNFTVTL--NNSNLYYMASRSFGDISSATILGDVRLLSAGICVVFIYVQLMLGKFNLVEQRAFLSLTGIASVAMAILVSYGLCSAFGVFYGPVHSILPFLLLGIGIDDMFVIVQCWSNLNKEEMK-RSLPVRIGITMKHAGVSITITSVTDFAAFAVGATTVLPSLRSFCIYSAVGILATYLFQASFFVAWLTLDQRRIESHRDGMLPCFVHR 560          

Query:    3 FLDKVSSVIVGGFERFFYWYGKLISRSPWLFLIGCLVGAGLCGIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQSWDDVCKRVPVIDLPGL-------GKQVQGPGNL--------RQSPCDDPSANDYDPSICLDSEIYCQVLDQSLSEACLETSILELFG----YEAETYD---NLDEESILKKVNEDTPTSVVFKRPIDIGQLLS-LTRDADGKIIGARAASLSWLGQVDLEHISDGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYKHKIEPAEKESEADYEYLSQKVFRIVGQIITKPLVK 535
             L+K+    +   E  F  YG+ ++R P + ++ C+    +CG GL   R E    KLW+P  SD+  NN+W+  N+P D R+N+++LT  NVLT  +L+ M+ + +S+ T+   + ++WDD C + PVI +P L        ++++   +L        + +   DP       SI    + YC ++   +  AC+E SILELFG    Y+  T D    L +E +L  +N     S +F  P +    LS +  +  G+IIGA+A  + WLG++++       +   G G P+    L++E  + ++      +    G +   N+A+ + DIA  TIIGD      G+ ++F YV IMLGKF+CVE R +LS VG+  + + I+V+YG+CSA G FYGPMH+V+PFLMLGIGIDDMFVI+QC+D L   E   ++  +  G  MK AG AITVTS TD + F VG+ T LPAL+SFC+Y  VGI+A + FQ++FF+A + LD RR+  NRNG   CY H   P       + +   Q+VF+   + + K  VK
Sbjct:   16 LLNKLQGSTLRILEDVFQSYGEFVARHPVIVILSCVALTCVCGGGLYWFRAENEGVKLWIPYNSDYRLNNDWMFENYPRDLRFNSLILTGENVLTAQVLRTMYRVSKSIRTMRNINNETWDDHCMKRPVIKVPSLFDIFGRKRREIKFDDDLFGDEFDEEKDTVITDPLKLATQFSIDEYPDPYCGIV-TGMPLACMELSILELFGQGGDYDERTDDVMETLTDEIVLDVINNKN-VSGIFLTPYNFTSYLSNIEYNTQGEIIGAKATYIIWLGRMNMTEAKLNPA--PGRGEPISMSMLQWEGDMLEVM--LNKSDYPKGLESFPNVARSFGDIAGSTIIGDITFFVAGYIMMFTYVQIMLGKFSCVEHRTYLSTVGILGVIMGIIVSYGICSAAGHFYGPMHSVMPFLMLGIGIDDMFVIIQCWDTLSEEEKK-ENLVKRFGFLMKQAGAAITVTSATDVIAFGVGAFTILPALQSFCIYAAVGIVATFVFQSSFFLAWMNLDQRRIESNRNGCCPCYVH---PETNNQTQERKGALQRVFKKYAEYLIKTPVK 561          

Query:    4 LDKVSSVIVGGFERFFYWYGKLISRSPWLFLIGCLVGAGLCGIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQSWDDVCKRVPVIDLPGL-------GKQVQGPGNL--------RQSPCDDPSANDYDPSICLDSEIYCQVLDQSLSEACLETSILELFG----YEAETYD---NLDEESILKKVNEDTPTSVVFKRPIDIGQLLS-LTRDADGKIIGARAASLSWLGQVDLEHISDGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYKHKIEPAEKESEADYEYLSQKVFRIVGQIITKPLVK 535
            L+K+    +   E  F  YG+ ++R P + ++ C+    +CG GL   R E    KLW+P  SD+  NN+W+  N+P D R+N+++LT  NVLT  +L+ M+ + +S+ T+   + ++WDD C + PVI +P L        ++++   +L        + +   DP       SI    + YC ++   +  AC+E SILELFG    Y+  T D    L +E +L  +N     S +F  P +    LS +  +  G+IIGA+A  + WLG++++       +   G G P+    L++E  + ++      +    G +   N+A+ + DIA  TIIGD      G+ ++F YV IMLGKF+CVE R +LS VG+  + + I+V+YG+CSA G FYGPMH+V+PFLMLGIGIDDMFVI+QC+D L   E   ++  +  G  MK AG AITVTS TD + F VG+ T LPAL+SFC+Y  VGI+A + FQ++FF+A + LD RR+  NRNG   CY H   P       + +   Q+VF+   + + K  VK
Sbjct:   17 LNKLQGSTLRILEDVFQSYGEFVARHPVIVILSCVALTCVCGGGLYWFRAENEGVKLWIPYNSDYRLNNDWMFENYPRDLRFNSLILTGENVLTAQVLRTMYRVSKSIRTMRNINNETWDDHCMKRPVIKVPSLFDIFGRKRREIKFDDDLFGDEFDEEKDTVITDPLKLATQFSIDEYPDPYCGIV-TGMPLACMELSILELFGQGGDYDERTDDVMETLTDEIVLDVINNKN-VSGIFLTPYNFTSYLSNIEYNTQGEIIGAKATYIIWLGRMNMTEAKLNPA--PGRGEPISMSMLQWEGDMLEVM--LNKSDYPKGLESFPNVARSFGDIAGSTIIGDITFFVAGYIMMFTYVQIMLGKFSCVEHRTYLSTVGILGVIMGIIVSYGICSAAGHFYGPMHSVMPFLMLGIGIDDMFVIIQCWDTLSEEEKK-ENLVKRFGFLMKQAGAAITVTSATDVIAFGVGAFTILPALQSFCIYAAVGIVATFVFQSSFFLAWMNLDQRRIESNRNGCCPCYVH---PETNNQTQERKGALQRVFKKYAEYLIKTPVK 561          

Query:    6 KVSSVIVGGFERFFYWYGKLISRSPWLFLIGCLVGAGLCGIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQSWDDVCKRVPVIDLPGLGKQVQGPGNL--RQSPCDDPSANDYDPSICLDSEIYCQVLDQSLSEACLETSILELFGYEAETYDNLDEESILKKVNEDTPTSVVFKRPIDIGQLL-SLTRDADGKIIGARAASLSWLGQVDLEHIS-DGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYKHKIEPAEKESEADYE------YLSQKVFRIVGQIITKPLVKG 536
            K+S++I+ G E FFY +G  ++  PW  ++GCL    L   G++   +E +  KLWVP  SDF+ +  WL + F    R  ++L+TAPNVL P +L+++ +I   V  +N  DG +W+D+C R+PV+D     ++     NL   +   D     ++D    L  ++YC ++++ L  AC++ S+LEL+ +  +   NL EE I+K +N  T  S V+  P D  QLL ++ R+  G + GA A    ++  +D   ++ D   + AGT        L++E K  D+ +         G ++     + + DI+A ++  D   + VG  ++F+YV I + KFN VE R  L  VGL  I +  +V  G CS  G+ YGP+H  +PFL+LGIG+DD+FVI+ C+ NL          E+M G TM+ AGV+IT+T++TD   F+VG+ T LP+L+SFCLY   G++  Y FQ +FFVA   LD RR+ +NRN  L CYKH+       SE +Y         S+ VF   G+++   L  G
Sbjct:   13 KLSAIILLGLESFFYRFGHAVACHPWSVILGCLGFVALSSFGILRFHQEKHPIKLWVPKNSDFIHDTNWLTSKFREGYRIQSILITAPNVLEPQVLQKLQDIQNKVENLN-ADGITWEDICFRIPVVDFNFKRRKRDVKENLILAEDYVDVEEDFEFDLGSILGYDLYCNIINR-LETACMQHSLLELWKFNEQKIHNLTEEKIIKALNR-TTVSPVYGHPTDYLQLLGNVRRNETGHVTGASALLSLYMVHIDFMSVNFDEDGNEAGTADWATKPILKWEQKFMDMMEDVSKH--AQGIEVFYEAGRSFADISAASMFQDINKLIVGIILMFIYVQINVSKFNMVECRLILGSVGLLCILMAFVVACGFCSLLGISYGPVHTALPFLLLGIGVDDLFVIVTCWKNLNVGNNLVSLPEKM-GQTMRRAGVSITITTLTDVAAFLVGALTILPSLQSFCLYAAAGLLMTYIFQTSFFVACFVLDERRIKKNRNCALICYKHRDYKPNPCSEVEYSKPILYTVYSKAVFTKPGKLLVILLTLG 547          

Query:    4 LDKVSSVIVGGFERFFYWYGKLISRSPWLFLIGCLVGAGLCGIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQSWDDVCKRVPVIDLPGLGK----------------QVQGPGNLRQSPCDD------------------------PSANDYDPSICLDSEIYCQVLDQSLSEACLETSILELFGYEAETYDNLDEESILKKVNEDTPTSVVFKRPIDIGQLL--SLTRDADGKIIGARAASLSWLGQVDLEHISDGSS-SNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDH----ERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYKH---KIEPAEKESEADYEYLSQKVFRIVGQIITKPLVK 535
            L+KVS  I G  E FFY +G L++  P+ F+ G  +   L  +G +   +E    KLW+P  S F ++ EWL  NFP   R +  + TA NVL P +++ +FEIH+ V  +++ DG+ W+D+C ++P+       K                +V      R +  +D                        P   D+DPSI L  E YC +++ SL EAC E +  EL+ +      NL ++ I++ +N    TS +F R ++    L   +T +  G+IIGA A  L ++  ++   +  G S S+  TG   D  T  +E    ++ Q+   +L   G  +     + + DI    I  D  M+ VGF ++FVY+ IM+G+FN VE R FLS+ G+  +G  ++V YG+ +   L YGP++ ++PF++LGIGIDDMFVIMQC+ NL P  +  K      ERM G+TMKHAGV+ITVTS+TD   F VG+ST +P L+SFC+Y  +GIIAV+  QATFFVA  A+D +RL   RNG     K+   +  P+E   ++ Y+ + +  F    +II  P+ K
Sbjct:   18 LEKVSLAIQGSLENFFYRWGVLVATHPFKFIFGAFMFTALLALGFINFTQENRPDKLWIPRDSKFASDTEWLRNNFPSPLRESFAIFTAENVLVPEVMQAIFEIHERVGRISILDGKKWEDLCFKLPITKFNEASKYRRRRRRSVATTLPSREVLMTSENRTAREEDTFFGHAFDDFDNAFNEDFFNEVSSPHVVDWDPSIELPVETYCSMVN-SLDEACWEVNPTELWSFNRSLIHNLTKDDIVQVMNYQL-TSPIFGRKVNYTAELGGKITHNEKGEIIGAEAIRLKFVVAINQTAVDLGKSMSDFSTGETADEGTWLWEKAWTELMQNASKSL-PRGIQVYYANGRSWGDITESLIFEDGMMLVVGFLVMFVYISIMIGRFNMVEQRPFLSIAGITCVGFAVIVAYGIGAMCFLLYGPVNKILPFMLLGIGIDDMFVIMQCWSNLYPSCLTKKCKQSIPERM-GMTMKHAGVSITVTSLTDVAAFGVGASTIMPGLQSFCIYAAIGIIAVFLLQATFFVACFAVDQKRLEDRRNGFFPWIKYSESEFTPSEWSQKSYYQSVFEWFFF---KIILTPIGK 592          

Query:    1 MKFLDKVSSVIVGGFERFFYWYGKLISRSPWLFLIGCLVGAGLCGIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQSWDDVCKRVPV--IDLPGLGKQVQGPGNLRQSPCD--------------------DPSAND---------YDPSICLDSEIYCQVLDQSLSEACLETSILELFGYEAETYDNLDEESILKKVNEDTPTSVVFKRPIDIGQLL--SLTRDADGKIIGARAASLSWLGQVDLEHISDGSS-SNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDH----ERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYKHKIEP--AEKESEADY------EYLSQKVFRIVGQIITKPLVKG 536
            M  L K+S  I G  ERFFY +G +++  P+ F+  CL+   +CG+GL+    E    KLW+P  S F  N EWL  NFP   R ++V++TA NVL P I+K + EIH+SV  +++ D + W+D+C R+P+   DL    ++ + P N      D                    D S N+         +DP + L  +IYC ++D +L +AC E + LEL+ Y     ++L +E I++  N     S +F R ++    L  ++ R++ G+II A + SL W   ++   +  G +  + GTG   D   L +E +   +  S     M +G ++     + + DI+   I  D  M+  GF I+F+YV  MLGKFN VE R   +        ++ +++YG+ SA  L YGP++ ++PFL+LGIG+DDMFVI+QC++NL P  +   +     ERM G+ +KHAGV+ITVTS+TD   F VG+ST LP L+SFC+Y  +GI+A++  Q+TFFVA  ALD +R+ + RN    C +++ +       S+  Y      EY S+ +F  V + +   +  G
Sbjct:   24 MTSLQKISLAITGTMERFFYRWGFIVATYPYRFISVCLLFTAICGLGLVNFTLENRPDKLWIPRDSAFAHNTEWLRDNFPSPVRQSHVIITADNVLDPGIMKMILEIHESVKNISVFDNKKWEDICFRLPITKFDLERRRRRRRSPTNSSHHEYDAFFGSAFSGFDEFDSEFFTSDASTNNTTKGGDVRSFDPMLSLPEDIYCSIID-NLDDACWEINPLELWSYNRTEVESLTKEEIIQVFNTRL-ISPIFGRVVNYTADLGGNIERNSLGQIIKAESISLKWFVAINQSEVRAGRAVPDMGTGEVADETGLAWETEFIYLMDSITKQ-MPDGVNLYFATGRSFGDISQGLIFDDGLMLVAGFFIMFLYVSTMLGKFNLVEQRLMANKNRHCVSIISFIISYGVGSACFLVYGPVNKILPFLLLGIGVDDMFVIVQCWNNLFPDCLSKPNKLSIPERM-GMALKHAGVSITVTSLTDIAAFGVGASTILPGLQSFCVYAAIGILAIFLLQSTFFVAWFALDQKRVEERRNAYCCCIQYRDDKFIPNSYSQRSYAQIFFDEYFSKYLFTPVAKTLVITVTLG 601