EMLSAG00000004370, EMLSAG00000004370-687136 (gene) Lepeophtheirus salmonis
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Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of EMLSAG00000004370 vs. GO
Match: - (symbol:AN2119.2 "Uncharacterized protein" species:227321 "Aspergillus nidulans FGSC A4" [GO:0005576 "extracellular region" evidence=IDA] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 GO:GO:0016021 GO:GO:0007165 GO:GO:0005576 EMBL:BN001307 EMBL:AACD01000032 GO:GO:0030301 GO:GO:0008158 eggNOG:NOG149152 KO:K12385 OMA:YEYTPFL TIGRFAMs:TIGR00917 HOGENOM:HOG000036674 OrthoDB:EOG72VHFB RefSeq:XP_659723.1 ProteinModelPortal:Q5BBG1 STRING:162425.CADANIAP00008794 EnsemblFungi:CADANIAT00008794 GeneID:2875771 KEGG:ani:AN2119.2 Uniprot:Q5BBG1) HSP 1 Score: 416.001 bits (1068), Expect = 8.611e-125 Identity = 300/1056 (28.41%), Postives = 503/1056 (47.63%), Query Frame = 0
Query: 29 CACLDXKQACPKLDA---DEYKEILTLKNEYMNFPIAYSVLIVILLLMLLVGIF-----LIAIKIKAKNRI-------SSETQEESRKESIGWLL------------FQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDK-ITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVE-KAIKWEKSF---VKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFR-------NKKYFGI-----TLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKT---ISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGS-AGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSWSN---DCCMVDSQGKICI------------------------------------------LFSNFMAF---------------HTVLRTSNDFVQAIESTRILSDKFARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSGKIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIMGKRSAEEVYNDQ---------------AGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSFF 961
C+C+D CP+L A +E+ + L +++SV+++ + +L V F + + R+ S+ ++E G L T F ++G C+++ +I + + ++LS G V ++P+ LW S S + KE FF+E+F PF+R Q F N+ E + + ++ I ++I+ D+ ++L D+CYKP +C++QSV Y+ GS S+ + DT+ D LT C +P SCL PL + ++GG++ DS ++L + ALI+T+++ NH E +AI WE +F + ++ +N L ++F E S++ + +S+ D +V+ISY +MF+Y S AL N + TL + GI +VL S+ ++ GLF GVK T+II E++PFLVLAVG+DNIF++V R L++ + E+D I + I P++ +S +T+T AF LG MPAV FA+YA ++ IN + QIT F+++L+L+ KR++S + D CL+ + F+ Q + F K +P+L+ + VK V++ L+ L T + +GLD +P SY+ YF+ L Y++ GPPVYFV + N+++ + Q ++CG C+ YS ++ S + +++ +A + SWIDD+F W N DCC D GK+C +SN + F HT LRT +DF+++ S R ++D + E+ I FPYS +++++QY+S+ + + + I L G + G V I+I + G +++ G+ LNA+ VNL++ GI VE C + + RS E+ + G + SGI +T L+GV VL F++S IF Y+F V++++++ H LI LPV LS+F
Sbjct: 237 CSCVDCPDVCPELPAIKTEEHCHVGLLPC------LSFSVILIYSVFLLGVAGFSSYFTYRERRYRKPERVRLLQDPNPSDDEDEGDIVHAGGHLEYPHGYYKLNSMLDTVFSRIGSVCARFPALTIISSVVAVVLLSLGWLRFAVETDPVRLWVSPTSAAAKEKAFFDENFGPFYRAE------------QAFLVND---DETGDGRVLDYDTLTWWFGVESRIRRVISLDRGLSLDDICYKPTGD---ACVIQSVTGYFGGSLSNLD---------PDTWQDRLTHCASSPGD--------ASCLPDFSQPLRPEMILGGYE--------DSGNVL-DAKALIVTWVVNNHAPGSEEEAEAIDWEDTFRGIFQVVQEEAKNRGLR-VSFTTEASVEQELNKSSNTDAKIVVISYIIMFIYASLALGSVTMTWRSLINNPANALVQSKFTLGVVGIVIVLMSVSASVGLFSAAGVKVTLIIAEVIPFLVLAVGVDNIFLIVYEFER--LNVSHPDEEIDERISRAIGRIGPSIFLSAITETVAFALGVFVGMPAVRNFAIYAAGAVFINAVLQITMFVSVLALNQKRVESLRADCIPCLTVRKAHSGMPEDLAFDDQDREGILQKFIRKVYAPLLLNR-RVKVVVVITFLGILAAGLALTPEVAMGLDQRIALPSDSYLIDYFDDLSEYFNSGPPVYFV--TRNVNITKREHQRQLCGRFTTCEEYSLPFVLEQESKRSNVSYIAGATASWIDDFFYWLNPQQDCCYED--GKLCFEGRTPGWNISLTGMPEGAEFIHYLEKWIKSPTDASCPLGGKAPYSNALVFDPKRITTNASHFRTSHTPLRTQDDFIKSYISARRIADGLSAEHGIDVFPYSKTYIFFDQYVSIVQVAGTLLGSAVAIIFAITSILLGSVATGAVVTATVIMIVIDIIGSMAISGVSLNAVSLVNLVICVGIGVEFCAHIARAFMFPSRSIMEIVPSKFRGKDARSWTALVNVGGSVFSGITVTKLLGVCVLAFTRSKIFEIYYFRVWLALIIFAATHALIFLPVALSYF 1234
BLAST of EMLSAG00000004370 vs. GO
Match: - (symbol:AN2119 species:162425 "Aspergillus nidulans" [GO:0005576 "extracellular region" evidence=IDA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0030301 "cholesterol transport" evidence=IEA] [GO:0008158 "hedgehog receptor activity" evidence=IEA] [GO:0006665 "sphingolipid metabolic process" evidence=IEA] [GO:0046624 "sphingolipid transporter activity" evidence=IEA] [GO:0000329 "fungal-type vacuole membrane" evidence=IEA] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 GO:GO:0016021 GO:GO:0007165 GO:GO:0005576 EMBL:BN001307 EMBL:AACD01000032 GO:GO:0030301 GO:GO:0008158 eggNOG:NOG149152 KO:K12385 OMA:YEYTPFL TIGRFAMs:TIGR00917 HOGENOM:HOG000036674 OrthoDB:EOG72VHFB RefSeq:XP_659723.1 ProteinModelPortal:Q5BBG1 STRING:162425.CADANIAP00008794 EnsemblFungi:CADANIAT00008794 GeneID:2875771 KEGG:ani:AN2119.2 Uniprot:Q5BBG1) HSP 1 Score: 416.001 bits (1068), Expect = 8.611e-125 Identity = 300/1056 (28.41%), Postives = 503/1056 (47.63%), Query Frame = 0
Query: 29 CACLDXKQACPKLDA---DEYKEILTLKNEYMNFPIAYSVLIVILLLMLLVGIF-----LIAIKIKAKNRI-------SSETQEESRKESIGWLL------------FQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDK-ITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVE-KAIKWEKSF---VKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFR-------NKKYFGI-----TLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKT---ISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGS-AGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSWSN---DCCMVDSQGKICI------------------------------------------LFSNFMAF---------------HTVLRTSNDFVQAIESTRILSDKFARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSGKIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIMGKRSAEEVYNDQ---------------AGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSFF 961
C+C+D CP+L A +E+ + L +++SV+++ + +L V F + + R+ S+ ++E G L T F ++G C+++ +I + + ++LS G V ++P+ LW S S + KE FF+E+F PF+R Q F N+ E + + ++ I ++I+ D+ ++L D+CYKP +C++QSV Y+ GS S+ + DT+ D LT C +P SCL PL + ++GG++ DS ++L + ALI+T+++ NH E +AI WE +F + ++ +N L ++F E S++ + +S+ D +V+ISY +MF+Y S AL N + TL + GI +VL S+ ++ GLF GVK T+II E++PFLVLAVG+DNIF++V R L++ + E+D I + I P++ +S +T+T AF LG MPAV FA+YA ++ IN + QIT F+++L+L+ KR++S + D CL+ + F+ Q + F K +P+L+ + VK V++ L+ L T + +GLD +P SY+ YF+ L Y++ GPPVYFV + N+++ + Q ++CG C+ YS ++ S + +++ +A + SWIDD+F W N DCC D GK+C +SN + F HT LRT +DF+++ S R ++D + E+ I FPYS +++++QY+S+ + + + I L G + G V I+I + G +++ G+ LNA+ VNL++ GI VE C + + RS E+ + G + SGI +T L+GV VL F++S IF Y+F V++++++ H LI LPV LS+F
Sbjct: 237 CSCVDCPDVCPELPAIKTEEHCHVGLLPC------LSFSVILIYSVFLLGVAGFSSYFTYRERRYRKPERVRLLQDPNPSDDEDEGDIVHAGGHLEYPHGYYKLNSMLDTVFSRIGSVCARFPALTIISSVVAVVLLSLGWLRFAVETDPVRLWVSPTSAAAKEKAFFDENFGPFYRAE------------QAFLVND---DETGDGRVLDYDTLTWWFGVESRIRRVISLDRGLSLDDICYKPTGD---ACVIQSVTGYFGGSLSNLD---------PDTWQDRLTHCASSPGD--------ASCLPDFSQPLRPEMILGGYE--------DSGNVL-DAKALIVTWVVNNHAPGSEEEAEAIDWEDTFRGIFQVVQEEAKNRGLR-VSFTTEASVEQELNKSSNTDAKIVVISYIIMFIYASLALGSVTMTWRSLINNPANALVQSKFTLGVVGIVIVLMSVSASVGLFSAAGVKVTLIIAEVIPFLVLAVGVDNIFLIVYEFER--LNVSHPDEEIDERISRAIGRIGPSIFLSAITETVAFALGVFVGMPAVRNFAIYAAGAVFINAVLQITMFVSVLALNQKRVESLRADCIPCLTVRKAHSGMPEDLAFDDQDREGILQKFIRKVYAPLLLNR-RVKVVVVITFLGILAAGLALTPEVAMGLDQRIALPSDSYLIDYFDDLSEYFNSGPPVYFV--TRNVNITKREHQRQLCGRFTTCEEYSLPFVLEQESKRSNVSYIAGATASWIDDFFYWLNPQQDCCYED--GKLCFEGRTPGWNISLTGMPEGAEFIHYLEKWIKSPTDASCPLGGKAPYSNALVFDPKRITTNASHFRTSHTPLRTQDDFIKSYISARRIADGLSAEHGIDVFPYSKTYIFFDQYVSIVQVAGTLLGSAVAIIFAITSILLGSVATGAVVTATVIMIVIDIIGSMAISGVSLNAVSLVNLVICVGIGVEFCAHIARAFMFPSRSIMEIVPSKFRGKDARSWTALVNVGGSVFSGITVTKLLGVCVLAFTRSKIFEIYYFRVWLALIIFAATHALIFLPVALSYF 1234
BLAST of EMLSAG00000004370 vs. GO
Match: - (symbol:Npc1a "Niemann-Pick type C-1a" species:7227 "Drosophila melanogaster" [GO:0005765 "lysosomal membrane" evidence=ISS] [GO:0030301 "cholesterol transport" evidence=ISS] [GO:0008158 "hedgehog receptor activity" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0007591 "molting cycle, chitin-based cuticle" evidence=IMP] [GO:0016125 "sterol metabolic process" evidence=IMP] [GO:0045456 "ecdysteroid biosynthetic process" evidence=IMP] [GO:0032374 "regulation of cholesterol transport" evidence=IDA] [GO:0007291 "sperm individualization" evidence=IMP] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 GO:GO:0016021 GO:GO:0007165 GO:GO:0007291 GO:GO:0007591 GO:GO:0032374 GO:GO:0016125 GO:GO:0030301 GO:GO:0008158 GO:GO:0045456 eggNOG:NOG149152 OrthoDB:EOG7QRQT0 TIGRFAMs:TIGR00917 ChiTaRS:NPC1 EMBL:BT009977 ProteinModelPortal:Q7YU59 SMR:Q7YU59 STRING:7227.FBpp0079547 PaxDb:Q7YU59 PRIDE:Q7YU59 FlyBase:FBgn0024320 InParanoid:Q7YU59 Bgee:Q7YU59 Uniprot:Q7YU59) HSP 1 Score: 404.06 bits (1037), Expect = 2.526e-120 Identity = 256/763 (33.55%), Postives = 419/763 (54.91%), Query Frame = 0
Query: 18 CQLIIILNSKSCACLDXKQACPKLDADEYK----EILTLKNEYMNFPIAYSVLIVILLLMLLVGIFLIAIKIKAK-------NRISSE---TQEESRKESIGW---LLFQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDKITLQDVCYKPLAPE-----IPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFVKWI----ESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRN-KKYF---GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARR-KLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKS--QNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW---SNDCC 744
C + +C+C D +CP+ + + +I+ L + + + + ++ +L+ L+G FL N +S E ++ +S E +G +TFF K G + + LI + ++L G+ ++++T++P++LW+S NS+SR E +FF+ F PF+R +II N L + +N G TF +F +E +VL LQ+ I++I + L+D+CY PL+ + + C++QS+W Y+ + + D G TYLD L C+ NP+ CL+ P++ +GGF + ++ LAN A+I+TFL++NH K +E A+ WEK FV+++ ++N+ + +DIAF +E SI+D + S DVL +++SY +MF+Y++ +L + K+ F ITL I G+ +VL S++S+ G+FG+IG+ AT+II E++PFLVLAVG+DNIF+LV T +R + E E +V ++G ++ P++L+++L+++ F+LG LS MPAV FALYAG +L+I+FL QIT F+++ +LD KR + ++D+ C + K P S + + + FF P LMKK+ V+ SVMV+ L ++ I +GLD E MP+ S+V YF+ L ++GPPVYFV+ DLA S QN +C C+ S T + L S + T +A SWIDDYF W ++ CC
Sbjct: 234 CNQAVSSKLPACSCSDCDLSCPQGPPEPPRPEPFKIVGLDAYF----VIMAAVFLVGVLVFLMGSFLFTQGSSMDDNFQVDGNDVSDEMPYSENDSYFEKLGAHTETFLETFFTKWGTYFASNPGLTLIAGASLVVILGYGINFIEITTDPVKLWASPNSKSRLEREFFDTKFSPFYRLEQIIIKAVN---LPQIVHNTSNGP-YTFGPVFDREFLTKVLDLQEGIKEI-NANGTQLKDICYAPLSDDGSEIDVSQCVVQSIWGYFGDDRERLD-DHDEDNGFNVTYLDALYDCISNPYL----------CLAPYGGPVDPAIALGGFLPPGDQLTGSTKFELAN--AIILTFLVKNHHNKTDLENALTWEKKFVEFMTNYTKNNMSQY--MDIAFTSERSIEDELNRESQSDVLTILVSYLIMFMYIAISLGHVKEFKRVFIDSKITLGIGGVIIVLASVVSSVGVFGYIGLPATLIIVEVIPFLVLAVGVDNIFILVQTHQRDQRKPNETLEQQVGRILG----KVGPSILLTSLSESFCFFLGGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRREENRMDICCFIKGK------KPDSITSNEGLLYKFFSSVYVPFLMKKI-VRASVMVIFFAWLCFSIAIAPRIDIGLDQELAMPQDSFVLHYFQSLDENLNIGPPVYFVLKG---DLAYTNSSDQNLVCAGQYCNDDSVLTQIYLASRHSNQTYIARPASSWIDDYFDWAAAASSCC 958 HSP 2 Score: 137.887 bits (346), Expect = 1.435e-31 Identity = 93/264 (35.23%), Postives = 144/264 (54.55%), Query Frame = 0
Query: 719 KPDLTTLATSGQSWIDDYFSWSNDCCMVDSQGKICILFSNFMAFHTVLRTSNDFVQAIESTRILSDK---------------FARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIMGK------RSAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
PD T A +G + +SN S ++ I S FMA+HT+L++S D+ A+ES R +S A + FPYS+F+V+YEQYL+M +DTL S+ +L++ ++ + L G + L V ++ I++++ G + I LNA+ VNL++A GISVE C + S K R+A+ + + + SGI +T G+ VL F++S IF ++F +Y+ IVVIG HGLI LPVLLS+
Sbjct: 1004 NPD-DTCAKAGHAAYGGAVRYSN------SHERLNIEASYFMAYHTILKSSADYFLALESARKISANITQMLQGRLMSNGVPMASALTVEVFPYSVFYVFYEQYLTMWSDTLQSMGISVLSIFVVTFVLMGFDVHSALVVVITITMIVVNLGGLMYYWNISLNAVSLVNLVMAVGISVEFCSHLVHSFATSKSVSQIDRAADSL-SKMGSSIFSGITLTKFAGILVLAFAKSQIFQVFYFRMYLGIVVIGAAHGLIFLPVLLSY 1259
BLAST of EMLSAG00000004370 vs. GO
Match: - (symbol:Npc1 "Niemann-Pick type C1" species:10090 "Mus musculus" [GO:0005515 "protein binding" evidence=IPI] [GO:0005576 "extracellular region" evidence=IDA] [GO:0005635 "nuclear envelope" evidence=ISO;IDA] [GO:0005764 "lysosome" evidence=IDA] [GO:0005765 "lysosomal membrane" evidence=ISO] [GO:0005768 "endosome" evidence=IDA] [GO:0005783 "endoplasmic reticulum" evidence=ISO] [GO:0005794 "Golgi apparatus" evidence=IDA] [GO:0005886 "plasma membrane" evidence=IDA] [GO:0005887 "integral component of plasma membrane" evidence=ISO] [GO:0006486 "protein glycosylation" evidence=ISO;IDA] [GO:0006629 "lipid metabolic process" evidence=IEA] [GO:0006897 "endocytosis" evidence=IMP] [GO:0006914 "autophagy" evidence=ISO] [GO:0007628 "adult walking behavior" evidence=IGI] [GO:0008158 "hedgehog receptor activity" evidence=IEA] [GO:0008202 "steroid metabolic process" evidence=IEA] [GO:0008203 "cholesterol metabolic process" evidence=IEA] [GO:0015485 "cholesterol binding" evidence=ISO] [GO:0016020 "membrane" evidence=IDA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0016242 "negative regulation of macroautophagy" evidence=IGI;IMP] [GO:0030301 "cholesterol transport" evidence=ISO] [GO:0031982 "vesicle" evidence=IDA] [GO:0033344 "cholesterol efflux" evidence=ISO;IMP] [GO:0042493 "response to drug" evidence=IDA] [GO:0042632 "cholesterol homeostasis" evidence=ISO] [GO:0045121 "membrane raft" evidence=IDA] [GO:0046686 "response to cadmium ion" evidence=ISO] [GO:0048471 "perinuclear region of cytoplasm" evidence=ISO] [GO:0060548 "negative regulation of cell death" evidence=ISO] [GO:0070062 "extracellular vesicular exosome" evidence=ISO] [GO:0071383 "cellular response to steroid hormone stimulus" evidence=IDA] [GO:0071404 "cellular response to low-density lipoprotein particle stimulus" evidence=IDA] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 EMBL:AF003348 MGI:MGI:1097712 GO:GO:0005783 GO:GO:0005794 GO:GO:0046686 GO:GO:0048471 GO:GO:0007165 GO:GO:0005576 GO:GO:0005887 GO:GO:0005635 GO:GO:0006914 GO:GO:0045121 GO:GO:0031902 GO:GO:0005765 GO:GO:0042493 GO:GO:0008206 GO:GO:0005768 GO:GO:0006486 GO:GO:0008203 GO:GO:0006897 GO:GO:0005764 GO:GO:0015485 GO:GO:0033344 GO:GO:0042632 GO:GO:0007628 GO:GO:0031982 GO:GO:0060548 GO:GO:0007041 GO:GO:0008158 GO:GO:0071404 GO:GO:0071383 GO:GO:0016242 EMBL:AC102248 eggNOG:NOG149152 GeneTree:ENSGT00680000099777 KO:K12385 OrthoDB:EOG7QRQT0 CTD:4864 HOVERGEN:HBG003913 TreeFam:TF300416 TIGRFAMs:TIGR00917 EMBL:AF003349 EMBL:AC102096 EMBL:CH466622 PIR:T30188 RefSeq:NP_032746.2 UniGene:Mm.3484 ProteinModelPortal:O35604 SMR:O35604 ChEMBL:CHEMBL2321610 PhosphoSite:O35604 PaxDb:O35604 PRIDE:O35604 Ensembl:ENSMUST00000025279 GeneID:18145 KEGG:mmu:18145 UCSC:uc008ecb.1 HOGENOM:HOG000036674 InParanoid:O35604 OMA:ITRAFTM ChiTaRS:NPC1 NextBio:293400 PRO:PR:O35604 ArrayExpress:O35604 CleanEx:MM_NPC1 Genevestigator:O35604 Uniprot:O35604) HSP 1 Score: 399.823 bits (1026), Expect = 7.249e-119 Identity = 239/677 (35.30%), Postives = 372/677 (54.95%), Query Frame = 0
Query: 92 SSETQEESRKESIGWLL---FQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIIT---EDKITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHI-EKDRVEKAIKWEKSFVKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSWSNDCCMVDSQGKICILFS 757
SS+ E S + +G + F K G FC + ++ + V SSG+ +++VT+ P+ELWS+ +S++R E ++F++HF PFFRT LII N S Y G + F +E+ +QVL LQ IE I + +TLQD+C PL+P +C + SV NY+Q S++ + + +D Y H CV P ++ ++ + CL P+ V+GG+ N +AL++TF + N+ + +R+++A WEK F+ +++ N +N P L I+F AE SI+D + S+ DV VIISY +MF+Y+S AL ++ I+L IAGI +VL S+ + G+F ++G+ T+I+ E++PFLVLAVG+DNIF+LV T +R +E +D +G L E+AP M +S+ ++T AF+ G LS MPAV TF+L+AG ++LI+FL QIT F+++L LD+KR + LD+ CC+ +G D + +Y + FF+ Y +P+L+K V V + + LS ++ + +GLD +MP SYV YF+ L Y GPPVYFV+ + ++ K QN +CG GCD S + + T + + SWIDDYF W V Q C L++
Sbjct: 315 SSDKGEASCCDPLGAAFDDCLRRMFTKWGAFCVRNPTCIIFFSLAFITVCSSGLVFVQVTTNPVELWSAPHSQARLEKEYFDKHFGPFFRTEQLIIQAPNTSVHIYEPYPA--GADVPFGPPLNKEILHQVLDLQIAIESITASYNNETVTLQDICVAPLSPYNKNCTIMSVLNYFQNSHAVLDSQVGDDFYIYADYHTHFLYCVRAPASLNDTSLLHGPCLGTFGGPVFPWLVLGGYDDQN----------YNNATALVITFPVNNYYNDTERLQRAWAWEKEFISFVK-NYKN-PNLTISFTAERSIEDELNRESNSDVFTVIISYVVMFLYISLALGHIQSCSRLLVDSKISLGIAGILIVLSSVACSLGIFSYMGMPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDE---RLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFGALSSMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNHLDILCCV--RGADDGQGSHASESY---LFRFFKNYFAPLLLKDWLRPIVVAVFVGV-LSFSVAVVNKVDIGLDQSLSMPNDSYVIDYFKSLAQYLHSGPPVYFVLEE-GYNYSSRKGQNMVCGGMGCDNDSLVQQIFNAAELDTYTRVGFAPSSWIDDYFDW------VSPQSSCCRLYN 961 HSP 2 Score: 131.724 bits (330), Expect = 9.387e-30 Identity = 75/213 (35.21%), Postives = 130/213 (61.03%), Query Frame = 0
Query: 759 FMAFHTVLRTSNDFVQAIESTRILSDKF-----ARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIM---GKR--SAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
FM +HT+L+TS D+ A++ R+++ ++ ++ FPYS+F+V+YEQYL++ DT+ +++ L ++ L+ + G ++ + ++ IL+++ G + + GI LNA+ VNL+++CGISVE C + M G R AEE + SGI +T G+ VL F++S IF ++F +Y+++V++G HGLI LPVLLS+
Sbjct: 1037 FMTYHTILKTSADYTDAMKKARLIASNITETMRSKGSDYRVFPYSVFYVFYEQYLTIIDDTIFNLSVSLGSIFLVTLVVLGCELWSAVIMCITIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTMSTKGSRVSRAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFEIFYFRMYLAMVLLGATHGLIFLPVLLSY 1249
BLAST of EMLSAG00000004370 vs. GO
Match: - (symbol:NPC1 "Niemann-Pick type C1 protein" species:10029 "Cricetulus griseus" [GO:0005635 "nuclear envelope" evidence=ISS] [GO:0005783 "endoplasmic reticulum" evidence=ISS] [GO:0005887 "integral component of plasma membrane" evidence=ISS] [GO:0007041 "lysosomal transport" evidence=ISS] [GO:0008206 "bile acid metabolic process" evidence=ISS] [GO:0042632 "cholesterol homeostasis" evidence=ISS] [GO:0048471 "perinuclear region of cytoplasm" evidence=ISS] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 GO:GO:0005783 GO:GO:0048471 GO:GO:0007165 GO:GO:0005887 GO:GO:0005635 GO:GO:0008206 GO:GO:0042632 GO:GO:0007041 GO:GO:0030301 GO:GO:0008158 KO:K12385 CTD:4864 HOVERGEN:HBG003913 TIGRFAMs:TIGR00917 EMBL:AF182744 RefSeq:NP_001233616.1 ProteinModelPortal:Q9JLG3 GeneID:100689424 KEGG:cge:100689424 Uniprot:Q9JLG3) HSP 1 Score: 398.667 bits (1023), Expect = 2.124e-118 Identity = 235/667 (35.23%), Postives = 369/667 (55.32%), Query Frame = 0
Query: 92 SSETQEESRKESIGWLL---FQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIIT---EDKITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHI-EKDRVEKAIKWEKSFVKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW---SNDCC 744
+S+ E S + +G + F K G FC + V+ + + SSG+ +++VT+ P+ELWS+ +SR+R E ++F++HF PFFR LII N S Y + G + +F +E+ +QVL LQ IE I T +TLQD+C PL+P +C + SV NY+Q S+S + + +D Y H CV P ++ ++ + CL P+ V+GG+ D ++ N +AL++TF + N+ + +++++A WEK F+ +++S P L I+FIAE SI+D + S+ DV + ISY +MF+Y+S AL ++ I+L IAGI +VL S+ + G+F ++G+ T+I+ E++PFLVLAVG+DNIF+LV T +R +E +D +G L E+AP M +S+ ++T AF+ G LS MPAV TF+L+AG ++LI+FL QIT F+++L LD+KR + +LD+ CC+ DN + + + FF+ +P L+K + V + + LS ++ + +GLD +MP SYV YF+ L Y GPPVYFV+ + D T K QN +CG GCD S + + + T + + SWIDDYF W + CC
Sbjct: 315 TSDKGEASCCDPLGAAFDDCLRRMFTKWGAFCVRNPTCVIFFSLVFITACSSGLVFVRVTTNPVELWSAPHSRARLEKEYFDKHFGPFFRMEQLIIQAPNTSEHIYEPYPS--GSDVSFGPPLNKEILHQVLDLQIAIESITTSYNNKTVTLQDICVAPLSPYNKNCTIISVLNYFQNSHSVLDHQVGDDFYVYADYHTHFLYCVRAPTSLNDTSLLHDPCLGTFGGPVFPWLVLGGY---------DDQN-YNNATALVITFPVSNYYNDTEKLQRAQAWEKEFIDFVKSYKN--PNLTISFIAERSIEDELNRESNSDVFTIAISYAIMFLYISLALGHIKSCSRLLVDSKISLGIAGILIVLSSVACSLGVFSYMGMPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDE---RLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFGALSSMPAVHTFSLFAGLAVLIDFLLQITCFVSLLGLDIKRQEKNRLDILCCVG-----GTDNGRGIQASESYLFRFFKNSFAPFLLKDWLRPIVIAVFVGV-LSFSIAVMNKVEIGLDQSLSMPNDSYVIDYFKSLGQYLHSGPPVYFVLEEGH-DYTTHKGQNMVCGGMGCDNDSLVQQIFNAAELDNYTRIGFAPSSWIDDYFDWVAPQSSCC 957 HSP 2 Score: 130.954 bits (328), Expect = 1.996e-29 Identity = 76/213 (35.68%), Postives = 130/213 (61.03%), Query Frame = 0
Query: 759 FMAFHTVLRTSNDFVQAIESTRILSDKF-----ARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIM---GKR--SAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
FM +HTVL+TS D++ A++ ++++ ++ +N FPYS+F+V+YEQYL++ DT+ +++ L ++ L+ + G ++ + ++ IL+++ G + + I LNA+ VNL+++CGISVE C + M G R AEE + SGI +T G+ VL F++S IF ++F +Y++IV++G HGLI LPVLLS+
Sbjct: 1037 FMTYHTVLKTSADYIDAMKKAQLVARNITETMNSKGSNYRVFPYSVFYVFYEQYLTIIDDTIFNLSVSLGSIFLVTLVVLGCELWSAVIMCITIAMILVNMFGVMWLWDISLNAVSLVNLVMSCGISVEFCSHITRAFTMSTKGSRVSRAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFEIFYFRMYLAIVLLGATHGLIFLPVLLSY 1249
BLAST of EMLSAG00000004370 vs. GO
Match: - (symbol:npc1 "Niemann-Pick disease, type C1" species:7955 "Danio rerio" [GO:0008158 "hedgehog receptor activity" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0016020 "membrane" evidence=IEA] [GO:0030301 "cholesterol transport" evidence=IEA] [GO:0001666 "response to hypoxia" evidence=IDA] [GO:0006869 "lipid transport" evidence=ISS] [GO:0055113 "epiboly involved in gastrulation with mouth forming second" evidence=IMP] [GO:0035855 "megakaryocyte development" evidence=IMP] [GO:0009790 "embryo development" evidence=IMP] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 ZFIN:ZDB-GENE-030131-3161 GO:GO:0016021 GO:GO:0007165 GO:GO:0001666 GO:GO:0006869 GO:GO:0035855 GO:GO:0055113 GO:GO:0030301 GO:GO:0008158 TIGRFAMs:TIGR00917 EMBL:JF951427 UniGene:Dr.108239 Uniprot:F6N6I8) HSP 1 Score: 397.127 bits (1019), Expect = 7.378e-118 Identity = 227/655 (34.66%), Postives = 375/655 (57.25%), Query Frame = 0
Query: 113 FRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITE---DKITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHI-EKDRVEKAIKWEKSFVKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCC--LSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW---SNDCCM-VDSQGKIC 753
F + G C + + +++ + ++ + S+G+ ++++T+ P+ELWS+ +SR+R+E + F++HF PFFRT LII + ++ ++ + G FS I + +QVL LQ EIE +I E + +TL+D+C PL+P +C + SV NY+Q S+ + ++ + Y HL C +P ++ ++ + C+ P+ V+GG++ + N +AL TF + N + + +++ KA+ WEK F+++++ N EN P L ++F +E SI+D I+ S+ DV ++ISY +MFVY+S AL + + I+L IAGI +VL S+ + G+F +IG+ T+I+ E++PFLVLAVG+DNIF++V T +R E E+ IG L ++AP+M +S+ ++T AF+LG LS MPAV TF+L+AG ++ I+FL QI+ F+++L LD+KR ++ ++D+ CC LSD E KS + + FF+K +P ++K V V + + LS ++ + +GL+ +MP SYV YF L Y GPPVYFVV + D T + QN +CG GC+ S + S + T ++ SW+DDYF W + CC +S G C
Sbjct: 342 FSRWGSLCVRQPLTIILSSLVLICICSAGLSYMRITTNPVELWSAPSSRARQEKNCFDQHFGPFFRTEQLII---TTPWTEEGGFSTITGDIIPFSPILNLSLLHQVLDLQLEIENLIAEYKGENVTLKDICVSPLSPYNDNCTILSVLNYFQNSHEVLDHEFQDEFFLYNDYHTHLLYCASSPTSLDDTSRLHDPCMGTFGGPVFPWLVLGGYE----------DSAYNNATALFFTFPVTNCLNDTEKLGKALAWEKEFIRFMK-NYEN-PNLTVSFSSERSIEDEIDRESNSDVSTIVISYIIMFVYISVALGRINSCRTLLVDSKISLGIAGILIVLSSVACSLGIFSYIGIPLTLIVIEVIPFLVLAVGVDNIFIIVQTYQRDE---RMPEEELHQQIGRILGDVAPSMFLSSFSETVAFFLGALSTMPAVRTFSLFAGLAIFIDFLLQISCFVSLLGLDIKRQEANRMDILCCVKLSDGQE-----EKS----EGWLFRFFKKIYAPFILKDWVRPLVVAVFVGM-LSFSIAVVNKVEIGLEQTLSMPDDSYVLNYFGNLSKYLHTGPPVYFVVEDGH-DYKTFEGQNAVCGGVGCNNDSLVQQIYTASLMSNYTRISNVPSSWLDDYFDWVKPQSTCCRYYNSTGAFC 967 HSP 2 Score: 133.65 bits (335), Expect = 2.593e-30 Identity = 78/213 (36.62%), Postives = 128/213 (60.09%), Query Frame = 0
Query: 759 FMAFHTVLRTSNDFVQAIESTRILSDKFAR-----ENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSGKIVIGLYTVTF-VSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIMGKRS-----AEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
FM++HT+L+ S+DF+ A++ R L+D + + + FPYS+F+V+YEQYL++ DT +++ L + ++ L G + V F ++ ILI++ G + + I LNA+ VNL+++CGISVE C + + + RS AEE + SGI +T G+ +L S+S IF ++F +Y++IV++G HGLI LPVLLS+
Sbjct: 1037 FMSYHTILKNSSDFINAMKMARELTDNITQTLSTHDKSYKVFPYSVFYVFYEQYLTIVDDTALNLGVSLSAIFIVTAVLLGFELWSAVLVCFTIAMILINMFGVMWLWSISLNAVSLVNLVMSCGISVEFCSHIVRAFSISTRSSRVERAEEALAHMGSSVFSGITLTKFGGILILALSKSQIFQIFYFRMYLAIVLLGAAHGLIFLPVLLSY 1249
BLAST of EMLSAG00000004370 vs. GO
Match: - (symbol:NPC1 "Uncharacterized protein" species:9615 "Canis lupus familiaris" [GO:0005576 "extracellular region" evidence=IEA] [GO:0005635 "nuclear envelope" evidence=IEA] [GO:0005765 "lysosomal membrane" evidence=IEA] [GO:0005768 "endosome" evidence=IEA] [GO:0005783 "endoplasmic reticulum" evidence=IEA] [GO:0005794 "Golgi apparatus" evidence=IEA] [GO:0005887 "integral component of plasma membrane" evidence=IEA] [GO:0006486 "protein glycosylation" evidence=IEA] [GO:0006897 "endocytosis" evidence=IEA] [GO:0006914 "autophagy" evidence=IEA] [GO:0007628 "adult walking behavior" evidence=IEA] [GO:0008158 "hedgehog receptor activity" evidence=IEA] [GO:0015485 "cholesterol binding" evidence=IEA] [GO:0016242 "negative regulation of macroautophagy" evidence=IEA] [GO:0031982 "vesicle" evidence=IEA] [GO:0033344 "cholesterol efflux" evidence=IEA] [GO:0042493 "response to drug" evidence=IEA] [GO:0045121 "membrane raft" evidence=IEA] [GO:0048471 "perinuclear region of cytoplasm" evidence=IEA] [GO:0071383 "cellular response to steroid hormone stimulus" evidence=IEA] [GO:0071404 "cellular response to low-density lipoprotein particle stimulus" evidence=IEA] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 GO:GO:0005783 GO:GO:0005794 GO:GO:0048471 GO:GO:0007165 GO:GO:0005576 GO:GO:0005887 GO:GO:0005635 GO:GO:0006914 GO:GO:0045121 GO:GO:0042493 GO:GO:0005768 GO:GO:0006486 GO:GO:0006897 GO:GO:0005764 GO:GO:0015485 GO:GO:0033344 GO:GO:0007628 GO:GO:0031982 GO:GO:0008158 GO:GO:0071404 GO:GO:0071383 GO:GO:0016242 GeneTree:ENSGT00680000099777 OrthoDB:EOG7QRQT0 OMA:YEYTPFL TreeFam:TF300416 TIGRFAMs:TIGR00917 EMBL:AAEX03005455 Ensembl:ENSCAFT00000028892 Uniprot:F1PB50) HSP 1 Score: 396.741 bits (1018), Expect = 9.577e-118 Identity = 240/679 (35.35%), Postives = 379/679 (55.82%), Query Frame = 0
Query: 92 SSETQEESRKESIGWLLFQTFFRKL----GYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIIT---EDKITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHI-EKDRVEKAIKWEKSFVKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLS-DKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW---SNDCCMV-DSQGKIC 753
+ +T E S +++G F+ R+L G FC + ++ + SSG+ + +VT+ P++LWS+ S++R E ++F+ HF PFFRT LII + S Y + G + F + +QVL LQ IE I + +TLQD+C PL+P +C + SV NY+Q S+S + I +D Y HL CV P ++ ++ + CL P+ V+GG+ N +AL++TF + N+ + +++++A WEK F+ +++ N EN P L I+F E SI+D + S+GDV V+ISY +MF+Y+S AL ++ F I+L IAGI +VL S++ + G+F + G+ T+I+ E++PFLVLAVG+DNIF+LV T +R L+G +E +G L E+AP+M +S+ ++ AF+LG LS+MPAV TF+L+AG ++LI+FL QIT F+++L LDLKR + +LD+ CCL+ +G + +S + FF+ SP L+K + V + I LS ++ + +GLD +MP SY+ YF+ LK Y GPPVYFV+ + D +++ QN +CG GC+ S + + + T + + SWIDDYF W + CC V +S + C
Sbjct: 316 AGDTGEASCCDALG-AAFEGCLRRLFTQWGSFCIRNPGCIIFFSLAFIAACSSGLVFSRVTTNPVDLWSAPGSQARLEKEYFDAHFGPFFRTEQLIIQAPHTSVHTYQPYPS--GSDVPFGPPLDIGILHQVLDLQTAIENITATYNNETVTLQDICVAPLSPYNKNCTIMSVLNYFQNSHSMLDHKIGDDFYVYADYHTHLLYCVRAPASLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDQN----------YNNATALVITFPVNNYYNDTEKLQRAQAWEKEFINFVK-NYEN-PNLTISFTTERSIEDELNRESNGDVFTVLISYAVMFLYISIALGHIKSCSRFLVDSKISLGIAGILIVLSSVMCSLGIFSYFGIPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDE-RLQGETLE--QQLGRVLGEVAPSMFLSSFSEAVAFFLGALSQMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDLKRQEKNRLDVLCCLTGSEGGTGIQASES------CLFRFFKNSYSPFLLKDWMRPIVIAVFVGI-LSFSIAVLNKVEIGLDQSLSMPDDSYMMDYFKSLK-YLHAGPPVYFVLEEGH-DYTSLEGQNMVCGGMGCNNDSLVQQIFSAAQLDNYTRIGFAPSSWIDDYFDWVKPQSSCCRVYNSTDQFC 967 HSP 2 Score: 130.183 bits (326), Expect = 2.911e-29 Identity = 77/213 (36.15%), Postives = 126/213 (59.15%), Query Frame = 0
Query: 759 FMAFHTVLRTSNDFVQAIESTRILSDKFARENNITS-----FPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEIC---IGYLTSVIMGKR--SAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
FM +HTVL+TS DF A+ +++ + ++ FPYS+F+V+YEQYL++ DT+ +++ L + L+ L G ++ + ++ IL+++ G + + GI LNA+ VNL+++CGISVE C T G R AEE + + SGI +T G+ VL F++S IF ++F +Y+++V++G HGLI LPVLLS+
Sbjct: 1037 FMTYHTVLQTSADFTDAMRKAILIASNITKTMSLKGSHYRVFPYSVFYVFYEQYLTIIDDTIFNLSVSLGAIFLVTLVLLGCELWSAVIMCVTIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSAKGSRVERAEEALSHMGSSVFSGITLTKFGGIVVLAFAKSQIFQVFYFRMYLAMVLLGATHGLIFLPVLLSY 1249
BLAST of EMLSAG00000004370 vs. GO
Match: - (symbol:Q8MKD8 "Niemann-Pick C1" species:9685 "Felis catus" [GO:0005635 "nuclear envelope" evidence=ISS] [GO:0005783 "endoplasmic reticulum" evidence=ISS] [GO:0005887 "integral component of plasma membrane" evidence=ISS] [GO:0007041 "lysosomal transport" evidence=ISS] [GO:0008206 "bile acid metabolic process" evidence=ISS] [GO:0042632 "cholesterol homeostasis" evidence=ISS] [GO:0048471 "perinuclear region of cytoplasm" evidence=ISS] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 GO:GO:0005783 GO:GO:0048471 GO:GO:0007165 GO:GO:0005887 GO:GO:0005635 GO:GO:0008206 GO:GO:0042632 GO:GO:0007041 GO:GO:0030301 GO:GO:0008158 HOVERGEN:HBG003913 TIGRFAMs:TIGR00917 EMBL:AF503634 ProteinModelPortal:Q8MKD8 Uniprot:Q8MKD8) HSP 1 Score: 395.201 bits (1014), Expect = 3.622e-117 Identity = 241/689 (34.98%), Postives = 382/689 (55.44%), Query Frame = 0
Query: 81 IAIKIKAKNRISSETQEESRKESIGWLLFQTFFRKL----GYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIIT---EDKITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHI-EKDRVEKAIKWEKSFVKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW---SNDCCMV-DSQGKIC 753
IA + A +R E S +++G F+ R+L G FC + ++ + SSG+ +++VT+ P++LWS+ +S++R E ++F+ HF PFFRT LII + S Y + G + F + +QVL LQ IE I + +TLQD+C PL+P +C + SV NY+Q S+S + I +D Y HL CV P ++ ++ + CL P+ V+GG+ N +AL++TF + N+ + +R++KA WEK F+ +++ N +N P L I+F E SI+D + S+GD+ VIISY +MF+Y+S AL ++ I+L IAGI +VL S+ + G+F ++G+ T+I+ E++PFLVLAVG+DNIF+LV T +R L G + D +G L E+AP+M +S+ ++ AF+LG LSKMPAV TF+L+AG ++LI+FL QIT F+++L LD+KR + +LD+ CC+ +G D + ++ + + F+ SP+L+K + + + + LS ++ + +GLD +MP SYV YF+ LK Y GPPVYFV+ + D ++K QN +CG GC+ S + + T + + SWIDDYF W + CC V +S + C
Sbjct: 309 IAFSVNANDR-----GEASCCDALG-AAFEGCLRRLFSQWGSFCVRNPGPIIFFSLAFIAACSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDTHFGPFFRTEQLIIQAPHTSAHTYQPYPS--GSDVPFGPPLDLAILHQVLDLQTAIENITASYNNETVTLQDICVAPLSPYNKNCTILSVLNYFQNSHSMLDHEIGDDFFVYADYHTHLLYCVRAPASLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDQN----------YNNATALVITFPVNNYYNDTERLQKAHVWEKEFINFVK-NYKN-PNLTISFTTERSIEDELNRESNGDIFTVIISYAIMFLYISIALGHIKSCSRLLVDSKISLGIAGILIVLSSVACSLGIFSYVGIPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDE-RLHGETL--DQQLGRVLGEVAPSMFLSSFSEAVAFFLGALSKMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNRLDVLCCV--RGSEDGTSVQAS---ESCLFRLFKHSYSPLLLKDWMRPIVIAIFVGV-LSFSVAVLNKVEIGLDQSLSMPDDSYVMDYFKSLK-YLHAGPPVYFVLEEGH-DYTSLKGQNMVCGGMGCNNDSLVQQIFNAAQLDSYTRIGFAPSSWIDDYFDWVKPQSSCCRVYNSTDRFC 966 HSP 2 Score: 132.109 bits (331), Expect = 7.702e-30 Identity = 78/213 (36.62%), Postives = 126/213 (59.15%), Query Frame = 0
Query: 759 FMAFHTVLRTSNDFVQAIESTRILSDKFARE-----NNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEIC---IGYLTSVIMGKRS--AEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
FM +HTVL+TS DF A+ +++ + +N FPYS+F+V+YEQYL++ DT+ +++ L + L+ L G + + ++ IL+++ G + + GI LNA+ VNL+++CGISVE C T + G R+ AEE + SGI +T G+ VL F++S IF ++F +Y+++V++G HGLI LPVLLS+
Sbjct: 1036 FMTYHTVLQTSADFTDAMRKANLIASNITKTMGLEGSNYRVFPYSVFYVFYEQYLTIIDDTIFNLSVSLGAIFLVTVILLGCDLWSAVIMCITIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRAQRAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSY 1248
BLAST of EMLSAG00000004370 vs. GO
Match: - (symbol:Q8MI49 "Mutant Niemann-Pick C1" species:9685 "Felis catus" [GO:0005635 "nuclear envelope" evidence=ISS] [GO:0005783 "endoplasmic reticulum" evidence=ISS] [GO:0005887 "integral component of plasma membrane" evidence=ISS] [GO:0007041 "lysosomal transport" evidence=ISS] [GO:0008206 "bile acid metabolic process" evidence=ISS] [GO:0042632 "cholesterol homeostasis" evidence=ISS] [GO:0048471 "perinuclear region of cytoplasm" evidence=ISS] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 GO:GO:0005783 GO:GO:0048471 GO:GO:0007165 GO:GO:0005887 GO:GO:0005635 GO:GO:0008206 GO:GO:0042632 GO:GO:0007041 GO:GO:0030301 GO:GO:0008158 eggNOG:NOG149152 HOVERGEN:HBG003913 TIGRFAMs:TIGR00917 EMBL:AF503633 ProteinModelPortal:Q8MI49 STRING:9685.ENSFCAP00000000483 Uniprot:Q8MI49) HSP 1 Score: 394.43 bits (1012), Expect = 6.745e-117 Identity = 240/689 (34.83%), Postives = 382/689 (55.44%), Query Frame = 0
Query: 81 IAIKIKAKNRISSETQEESRKESIGWLLFQTFFRKL----GYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIIT---EDKITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHI-EKDRVEKAIKWEKSFVKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW----SNDCCMVDSQGKIC 753
IA + A +R E S +++G F+ R+L G FC + ++ + SSG+ +++VT+ P++LWS+ +S++R E ++F+ HF PFFRT LII + S Y + G + F + +QVL LQ IE I + +TLQD+C PL+P +C + SV NY+Q S+S + I +D Y HL CV P ++ ++ + CL P+ V+GG+ N +AL++TF + N+ + +R++KA WEK F+ +++ N +N P L I+F E SI+D + S+GD+ VIISY +MF+Y+S AL ++ I+L IAGI +VL S+ + G+F ++G+ T+I+ E++PFLVLAVG+DNIF+LV T +R L G + D +G L E+AP+M +S+ ++ AF+LG LSKMPAV TF+L+AG ++LI+FL QIT F+++L LD+KR + +LD+ CC+ +G D + ++ + + F+ SP+L+K + + + + LS ++ + +GLD +MP SYV YF+ LK Y GPPVYFV+ + D ++K QN +CG GC+ S + + T + + SWIDDYF W S+ C + +S + C
Sbjct: 309 IAFSVNANDR-----GEASCCDALG-AAFEGCLRRLFSQWGSFCVRNPGPIIFFSLAFIAACSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDTHFGPFFRTEQLIIQAPHTSAHTYQPYPS--GSDVPFGPPLDLAILHQVLDLQTAIENITASYNNETVTLQDICVAPLSPYNKNCTILSVLNYFQNSHSMLDHEIGDDFFVYADYHTHLLYCVRAPASLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDQN----------YNNATALVITFPVNNYYNDTERLQKAHVWEKEFINFVK-NYKN-PNLTISFTTERSIEDELNRESNGDIFTVIISYAIMFLYISIALGHIKSCSRLLVDSKISLGIAGILIVLSSVACSLGIFSYVGIPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDE-RLHGETL--DQQLGRVLGEVAPSMFLSSFSEAVAFFLGALSKMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNRLDVLCCV--RGSEDGTSVQAS---ESCLFRLFKHSYSPLLLKDWMRPIVIAIFVGV-LSFSVAVLNKVEIGLDQSLSMPDDSYVMDYFKSLK-YLHAGPPVYFVLEEGH-DYTSLKGQNMVCGGMGCNNDSLVQQIFNAAQLDSYTRIGFAPSSWIDDYFDWVKPQSSSCRVYNSTDRFC 966 HSP 2 Score: 132.109 bits (331), Expect = 7.970e-30 Identity = 78/213 (36.62%), Postives = 126/213 (59.15%), Query Frame = 0
Query: 759 FMAFHTVLRTSNDFVQAIESTRILSDKFARE-----NNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEIC---IGYLTSVIMGKRS--AEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
FM +HTVL+TS DF A+ +++ + +N FPYS+F+V+YEQYL++ DT+ +++ L + L+ L G + + ++ IL+++ G + + GI LNA+ VNL+++CGISVE C T + G R+ AEE + SGI +T G+ VL F++S IF ++F +Y+++V++G HGLI LPVLLS+
Sbjct: 1036 FMTYHTVLQTSADFTDAMRKANLIASNITKTMGLEGSNYRVFPYSVFYVFYEQYLTIIDDTIFNLSVSLGAIFLVTVILLGCDLWSAVIMCITIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRAQRAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSY 1248
BLAST of EMLSAG00000004370 vs. GO
Match: - (symbol:NPC1 "Uncharacterized protein" species:9031 "Gallus gallus" [GO:0005576 "extracellular region" evidence=IEA] [GO:0005635 "nuclear envelope" evidence=IEA] [GO:0005765 "lysosomal membrane" evidence=IEA] [GO:0005768 "endosome" evidence=IEA] [GO:0005783 "endoplasmic reticulum" evidence=IEA] [GO:0005794 "Golgi apparatus" evidence=IEA] [GO:0005887 "integral component of plasma membrane" evidence=IEA] [GO:0006486 "protein glycosylation" evidence=IEA] [GO:0006897 "endocytosis" evidence=IEA] [GO:0006914 "autophagy" evidence=IEA] [GO:0007628 "adult walking behavior" evidence=IEA] [GO:0008158 "hedgehog receptor activity" evidence=IEA] [GO:0015485 "cholesterol binding" evidence=IEA] [GO:0016242 "negative regulation of macroautophagy" evidence=IEA] [GO:0031982 "vesicle" evidence=IEA] [GO:0033344 "cholesterol efflux" evidence=IEA] [GO:0042493 "response to drug" evidence=IEA] [GO:0045121 "membrane raft" evidence=IEA] [GO:0048471 "perinuclear region of cytoplasm" evidence=IEA] [GO:0071383 "cellular response to steroid hormone stimulus" evidence=IEA] [GO:0071404 "cellular response to low-density lipoprotein particle stimulus" evidence=IEA] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 GO:GO:0016021 GO:GO:0007165 GO:GO:0030301 GO:GO:0008158 GeneTree:ENSGT00680000099777 OrthoDB:EOG7QRQT0 TreeFam:TF300416 TIGRFAMs:TIGR00917 EMBL:AADN03002550 Ensembl:ENSGALT00000024240 Uniprot:F1NQT4) HSP 1 Score: 394.43 bits (1012), Expect = 9.772e-117 Identity = 231/681 (33.92%), Postives = 375/681 (55.07%), Query Frame = 0
Query: 92 SSETQEESRKESIGWLLFQTF-------FRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIIT---EDKITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHI-EKDRVEKAIKWEKSFVKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW---SNDCCMV-DSQGKIC 753
S+ + ++ K + G L + F F G FC + V++ + + + SG ++K T+ P++LWS+ +S++RKE ++F++HF PFFRT LII N Y + G + F +++ +QVL LQ I I + +TL+D+C PLAP +C + SV NY+Q S+S + ++ +D Y H CV P ++ ++ + CL P+ V+GG+ D N +AL++T + N+ + ++ KA+ WEK F+ +++ N +N P L I+F AE SI+D I S DV V+ISY +MFVY+S AL ++ I+L IAGI +VL S+ + G+F + GV T+I+ E++PFLVLA+G+DN+F++V T +R LEG + D IG L ++AP+M +S+ ++T AF+LGTLS MPAV TF+L+AG ++LI+F+ Q+T F+++L LD++R + +LD+ CC+ E+ + + + FF+ SP L+K + + + + LS + N+ +GLD +MP SYV YF+ L Y GPPVYFV+ + + +++ QN +CG GC+ S + + T + + SWIDDYF W + CC V ++ G+ C
Sbjct: 321 SANSHRDNGKITCGERLGERFENGLRMTFTSWGAFCVRNPRPVILFSVVFIAMCCSGFVYIKATTNPVDLWSAPSSQARKEKEYFDKHFGPFFRTEQLIIQAPNSHPDIYSPYPS--GADVPFGPPLNKDILHQVLDLQDAIVNIAASFDNETVTLKDICLAPLAPYNNNCTILSVLNYFQNSHSVLDHSVGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGAFGGPVFPWLVLGGYDGDN----------YNNATALVITLPVNNYYNDSKKIMKALAWEKEFINFLK-NYDN-PNLTISFSAERSIEDEINRESRSDVSTVVISYVVMFVYISIALGHIQSWGRLLVDSKISLGIAGILIVLSSVACSIGIFSYFGVPVTLIVAEVIPFLVLAIGVDNLFIIVQTLQRDE-RLEGETL--DKQIGRVLGDVAPSMFLSSFSETVAFFLGTLSTMPAVRTFSLFAGMAVLIDFILQVTCFVSLLGLDIRRQERNRLDILCCIKGSEEM-----RGVQRSESILFLFFKNLYSPYLLKDWMRPIVIALFVGL-LSFSTAVIHNVEIGLDQSLSMPDDSYVMNYFKQLGKYMHAGPPVYFVLEEGH-NYTSLEGQNMVCGGTGCNNDSLVQQVFNAAEISSYTRIGYAPSSWIDDYFDWVKPQSSCCRVYNTTGQFC 977 HSP 2 Score: 135.576 bits (340), Expect = 6.961e-31 Identity = 77/213 (36.15%), Postives = 128/213 (60.09%), Query Frame = 0
Query: 759 FMAFHTVLRTSNDFVQAIESTRILSDKFA-----RENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEIC---IGYLTSVIMGKR--SAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
FM +HTVL+ S+D++ A++ R ++D +E N FPYS+F+V+YEQYL++ D + ++ L ++ L+ L G ++ + ++ I++++ G + + GI LNA+ VNL+++CGI+VE C T G R AEE + + SGI +T G+ VL FS+S IF ++F +Y+++V++G HGLI LPVLLS+
Sbjct: 1047 FMTYHTVLKKSSDYIDAMKKARDIADNITETMGIKEKNYRVFPYSVFYVFYEQYLTIVNDAIFNLCISLGSIFLVTAVLLGFEVWAAVVVTVTIAMIIVNMFGVMWLWGISLNAVSLVNLVMSCGIAVEFCSHVTRAFTVSTKGSRVERAEEALSHMGSSVFSGITLTKFGGIVVLAFSKSQIFKIFYFRMYLAMVLLGATHGLIFLPVLLSY 1259
BLAST of EMLSAG00000004370 vs. C. finmarchicus
Match: gi|592794335|gb|GAXK01160233.1| (TSA: Calanus finmarchicus comp142827_c0_seq2 transcribed RNA sequence) HSP 1 Score: 421.394 bits (1082), Expect = 3.845e-126 Identity = 266/785 (33.89%), Postives = 427/785 (54.39%), Query Frame = 0
Query: 13 PEYLFCQLIIILNSKSCACLDXKQAC-----PKLDADEYKEILTLKNEYMN-----FPIAYSXXXXXXXXXXXXXXXXXAIKIKAKNRISSETQEESRKESIGWLLFQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNE---SFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQX-----------XXXXXXXXXXXXLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNI---TNDRGHQDTYLDHLTTCVENPFTI---KSSTAMGQS-----CLSKGFVPLEAKFVMGGFKTDKS--PESLDSEDILANTSALIMTFLLQN---HIEKDR----VEKAIKWEKSFVK----WIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYFG------ITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARR-KLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNST--NMDLATVKSQNRIC-GSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW 739
PE + CQ S C C + AC P+ + ++ K K ++ + +SV V+ + +V + I + K +I + + ++I + FF G F +++ V VL+ + I L GV LK+T++PIELW+S SRSR E DFF+ F PF+RTS++II +NE + ++KF + + YGKE F +F ++ + LKLQ+ E L +C PL+P +C + + W YW S + ++ G TYLDH CV+NP + + T +G CL+K P+ +V+GGF + + PES D A + A++M ++ N H EK+ +E+A+ WE+ FV+ W+E+ + + +D+AF +E S++D ++ ++GDV + +SY +MF+Y++ +L + G ITL + G+ +VL S+ ++ G+F GV AT+IIFEI+PFLVLAVG+DNIF+LV T +R K E E +V ++G E+AP+ML+S+LT++ F+LG LS MPAV FA+YAG +LLI+FL Q+T F+A++SLD+ R ++ K D+ CC+ +G P Y+ F+ +P L+ K V+ ++M+L ++ I +GLD E +MP+ S+V K+F ++K Y SVGPPVYFV+N+T ++DL QN +C G GC S + W +P+ + +AT+ +W+DDY +W
Sbjct: 1261 PEVISCQDTAPGYSTGCGCANCPAACSGSGVPEFNREDDKPFYDFKLGGLDGLSVIMGLVFSVGSVLFIGFSIVCVPS-VIPVTTKPKIGPKARTNLVNDAI-----EKFFTWWGKFAARHPVLVLVISLTIAFGLCCGVVKLKITTDPIELWASPTSRSRVEKDFFDTEFRPFYRTSLVIIK-ANENPSAGIEKFNFTDAYGKEYEFGAMFNKKFLKEALKLQQKIENITFQYEETEGNETVEHTYDLTRICNSPLSPLNTNCNINNAWAYWHDDESLLDKEFKPSSDSVGRNLTYLDHFLDCVKNPSMVSQQDTHTDLGDGNGGIGCLAKWGGPVNPYYVLGGFIPEGTTFPESPD----YAKSQAIVMQIIINNFDPHSEKEEDVKGLERAMAWEEKFVEFMKDWVENEMPEY--IDVAFTSERSVEDELDRETYGDVATIAVSYIIMFIYITLSLGQYGKFSLSGFMIESKITLGLFGVMIVLLSVFASIGIFAVAGVPATLIIFEIIPFLVLAVGVDNIFILVQTYQRDKKRPTETDEEQVGRVVG----EVAPSMLLSSLTESTCFFLGALSGMPAVRAFAMYAGMALLIDFLMQVTSFVALMSLDMARQRNNKFDILCCI--RGSKKDSEPVEGVLYR-----VFKHLYAPALLSKW-VRPAIMILFFGAACSSIAVVPRIGIGLDQELSMPEDSFVLKFFVYMKEYLSVGPPVYFVLNNTAGHLDLTDPSVQNLLCLGLGGCQENSLAGQVNSWRLQPNQSYIATAPMNWLDDYVTW 3540 HSP 2 Score: 119.013 bits (297), Expect = 3.357e-26 Identity = 84/219 (38.36%), Postives = 127/219 (57.99%), Query Frame = 0
Query: 757 SNFMAFHTVLRTSNDFVQAIESTRILSDKFAR--------ENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQXXXXXXXXXXXXCGISVEICIGYLTSVIMGKRSAEEVYNDQAGIL------MSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
SN MAFHT+LRTS D+ A++ R L+D E + FPYSIF+V+YEQYL+M DTL+S+ L+T+ ++ + L G + + + ILI++ + I LNA+ VNL++A GISVE C ++T + + N + ++ +SGI +T G+ VL F++S IF ++F +Y+ IV+IG HGLI LPVLLS+
Sbjct: 304 SNMMAFHTILRTSEDYYTALKRARELTDSITEMINANRTEEEKVNVFPYSIFYVFYEQYLTMWKDTLISVGISLVTIFVVTFLLMGFDLRSATIILFVIILILINLGALMYWWNITLNAVSLVNLVMAVGISVEFC-SHITRYFATHSHQDRIENARNSVIKMGSSVLSGITLTKFGGILVLAFAKSKIFTVFYFRMYLGIVLIGAAHGLIFLPVLLSY 957
BLAST of EMLSAG00000004370 vs. C. finmarchicus
Match: gi|592794336|gb|GAXK01160232.1| (TSA: Calanus finmarchicus comp142827_c0_seq1 transcribed RNA sequence) HSP 1 Score: 421.394 bits (1082), Expect = 4.187e-126 Identity = 266/785 (33.89%), Postives = 427/785 (54.39%), Query Frame = 0
Query: 13 PEYLFCQLIIILNSKSCACLDXKQAC-----PKLDADEYKEILTLKNEYMN-----FPIAYSXXXXXXXXXXXXXXXXXAIKIKAKNRISSETQEESRKESIGWLLFQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNE---SFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQX-----------XXXXXXXXXXXXLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNI---TNDRGHQDTYLDHLTTCVENPFTI---KSSTAMGQS-----CLSKGFVPLEAKFVMGGFKTDKS--PESLDSEDILANTSALIMTFLLQN---HIEKDR----VEKAIKWEKSFVK----WIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYFG------ITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARR-KLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNST--NMDLATVKSQNRIC-GSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW 739
PE + CQ S C C + AC P+ + ++ K K ++ + +SV V+ + +V + I + K +I + + ++I + FF G F +++ V VL+ + I L GV LK+T++PIELW+S SRSR E DFF+ F PF+RTS++II +NE + ++KF + + YGKE F +F ++ + LKLQ+ E L +C PL+P +C + + W YW S + ++ G TYLDH CV+NP + + T +G CL+K P+ +V+GGF + + PES D A + A++M ++ N H EK+ +E+A+ WE+ FV+ W+E+ + + +D+AF +E S++D ++ ++GDV + +SY +MF+Y++ +L + G ITL + G+ +VL S+ ++ G+F GV AT+IIFEI+PFLVLAVG+DNIF+LV T +R K E E +V ++G E+AP+ML+S+LT++ F+LG LS MPAV FA+YAG +LLI+FL Q+T F+A++SLD+ R ++ K D+ CC+ +G P Y+ F+ +P L+ K V+ ++M+L ++ I +GLD E +MP+ S+V K+F ++K Y SVGPPVYFV+N+T ++DL QN +C G GC S + W +P+ + +AT+ +W+DDY +W
Sbjct: 1281 PEVISCQDTAPGYSTGCGCANCPAACSGSGVPEFNREDDKPFYDFKLGGLDGLSVIMGLVFSVGSVLFIGFSIVCVPS-VIPVTTKPKIGPKARTNLVNDAI-----EKFFTWWGKFAARHPVLVLVISLTIAFGLCCGVVKLKITTDPIELWASPTSRSRVEKDFFDTEFRPFYRTSLVIIK-ANENPSAGIEKFNFTDAYGKEYEFGAMFNKKFLKEALKLQQKIENITFQYEETEGNETVEHTYDLTRICNSPLSPLNTNCNINNAWAYWHDDESLLDKEFKPSSDSVGRNLTYLDHFLDCVKNPSMVSQQDTHTDLGDGNGGIGCLAKWGGPVNPYYVLGGFIPEGTTFPESPD----YAKSQAIVMQIIINNFDPHSEKEEDVKGLERAMAWEEKFVEFMKDWVENEMPEY--IDVAFTSERSVEDELDRETYGDVATIAVSYIIMFIYITLSLGQYGKFSLSGFMIESKITLGLFGVMIVLLSVFASIGIFAVAGVPATLIIFEIIPFLVLAVGVDNIFILVQTYQRDKKRPTETDEEQVGRVVG----EVAPSMLLSSLTESTCFFLGALSGMPAVRAFAMYAGMALLIDFLMQVTSFVALMSLDMARQRNNKFDILCCI--RGSKKDSEPVEGVLYR-----VFKHLYAPALLSKW-VRPAIMILFFGAACSSIAVVPRIGIGLDQELSMPEDSFVLKFFVYMKEYLSVGPPVYFVLNNTAGHLDLTDPSVQNLLCLGLGGCQENSLAGQVNSWRLQPNQSYIATAPMNWLDDYVTW 3560 HSP 2 Score: 119.013 bits (297), Expect = 3.366e-26 Identity = 84/219 (38.36%), Postives = 127/219 (57.99%), Query Frame = 0
Query: 757 SNFMAFHTVLRTSNDFVQAIESTRILSDKFAR--------ENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQXXXXXXXXXXXXCGISVEICIGYLTSVIMGKRSAEEVYNDQAGIL------MSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
SN MAFHT+LRTS D+ A++ R L+D E + FPYSIF+V+YEQYL+M DTL+S+ L+T+ ++ + L G + + + ILI++ + I LNA+ VNL++A GISVE C ++T + + N + ++ +SGI +T G+ VL F++S IF ++F +Y+ IV+IG HGLI LPVLLS+
Sbjct: 324 SNMMAFHTILRTSEDYYTALKRARELTDSITEMINANRTEEEKVNVFPYSIFYVFYEQYLTMWKDTLISVGISLVTIFVVTFLLMGFDLRSATIILFVIILILINLGALMYWWNITLNAVSLVNLVMAVGISVEFC-SHITRYFATHSHQDRIENARNSVIKMGSSVLSGITLTKFGGILVLAFAKSKIFTVFYFRMYLGIVLIGAAHGLIFLPVLLSY 977
BLAST of EMLSAG00000004370 vs. C. finmarchicus
Match: gi|592809975|gb|GAXK01144593.1| (TSA: Calanus finmarchicus comp58031_c0_seq1 transcribed RNA sequence) HSP 1 Score: 415.616 bits (1067), Expect = 1.096e-123 Identity = 249/667 (37.33%), Postives = 379/667 (56.82%), Query Frame = 0
Query: 111 TFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSN--ESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQXX--------XXXXXXXXXXXLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQD------TYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGF--KTDKSPESLDSEDILANTSALIMTFLLQNHIEKDR-------VEKAIKWEKSFVKWIESNLENF--PLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFAL--TDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDS-LIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNST--NMDLATVKSQNRIC-GSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSWS 740
FF G +KY + V+I + + LS+GV +L+VT++PIELW+S SRSR E DFF+ F PF+RT+ +II E + +F + + + F IF + +VLKLQ++ E T+ L+ VC KPL+PEI C +Q+V YWQ + + G+ TYLDH C NP S + C+SK P+ + +GGF K PE+ + A++M+ ++ N+ K + +E+A++WEK F+ ++ EN ++IAF +E SI+D ++ ++GD++ + ISY +MFVY++F+L T F ITL + G+ +VL S+ ++ G FGF+GV AT+IIFEI+PFLVLAVG+DNIF+LV T +R+ +E E + +G + E+AP+ML+S+++++ F+LG LS MPAV FALYAG +L ++FL QIT F+++LSLD+ R +S + D+ CC+ + K + + + F+ P LMKK V+ SV+V+ ++ I +GLD E +MP SYV KYF +LK Y SVGPPVYFVVN+T +DL++ K QN++C G GC S + W P+ T +AT+ WID Y +W+
Sbjct: 1388 NFFTWWGTLAAKYPLPVIILSIAFAVGLSTGVIYLEVTTDPIELWASPTSRSRVEKDFFDSTFRPFYRTAQVIIHAKEMPEHGVTRFNFTDHLRNQLDFGPIFNKNFMKEVLKLQQKIEELEFKYKESDGTDQTYNLKKVCNKPLSPEINECNIQNVLAYWQDDEALLEKEKYDPEGNDGNVPRTWTYLDHFLACANNPTLTSQSDKLNIGCMSKWGGPVNPYYCLGGFIPKGSSFPENPEYH----KADAVVMSIIVDNYDPKSKDPNDIRGLERAMEWEKVFIDFMHDWEENEKPEYMEIAFNSERSIEDELDKETYGDIVTIAISYIIMFVYITFSLGQTSKCTVSMFMIESKITLGLGGVMIVLISVAASIGTFGFVGVPATLIIFEIIPFLVLAVGVDNIFILVQTYQRE----PRKEYESHAEHVGRVVGEVAPSMLLSSVSESTCFFLGALSDMPAVRAFALYAGVALFVDFLMQITCFVSLLSLDMMRQESNRFDIICCVR-------GSKKDQEQSEGMLFRLFKHLYGPFLMKKW-VRASVIVIFFGWACSSIAVVPKIEIGLDAEISMPDNSYVLKYFTFLKEYLSVGPPVYFVVNNTRGQLDLSSEKDQNKLCLGLPGCSENSLAGQIFNWQKAPESTYIATAPMPWIDGYITWA 3340 HSP 2 Score: 126.716 bits (317), Expect = 1.391e-28 Identity = 86/231 (37.23%), Postives = 136/231 (58.87%), Query Frame = 0
Query: 745 MVDSQGKICILFSNFMAFHTVLRTSNDFVQAIESTRILSDKFAR--------ENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQXXXXXXXXXXXXCGISVEICIGYLT---SVIMGKRSAEEVYN---DQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
+ ++ G + SN MAFH++L+TS D+ A+ R L+D E+++ FPYS+F+V+YEQYL+M DTL ++ L + L+ + L G +V + + I++++ G + I LNA+ VNL++A GISVE C ++T SV +GK E N + ++SGI +T G+ VL F++S IF ++F +Y+ IV+IG HGLI+LPVLLS+
Sbjct: 236 LANNGGSNSVRSSNMMAFHSILKTSKDYYMALARARELTDNVMEFVNNGTDPEDHVNIFPYSVFYVFYEQYLTMWRDTLQQLSISLAAIFLVTFVLMGFDLVSSCINLLIIVLIVLNLGGLMYWWHITLNAVSLVNLVMAVGISVEFC-SHMTRAFSVNIGKDRTERALNVLTNMGSSVLSGITLTKFGGIVVLAFAKSQIFSIFYFRMYLGIVLIGAAHGLILLPVLLSY 925
BLAST of EMLSAG00000004370 vs. C. finmarchicus
Match: gi|592765110|gb|GAXK01189458.1| (TSA: Calanus finmarchicus comp620364_c3_seq2 transcribed RNA sequence) HSP 1 Score: 357.066 bits (915), Expect = 2.381e-105 Identity = 210/590 (35.59%), Postives = 338/590 (57.29%), Query Frame = 0
Query: 117 GYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPS--NESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQXX--------XXXXXXXXXXXLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQD------TYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGF--KTDKSPESLDSEDILANTSALIMTFLLQNHIEKDR-------VEKAIKWEKSFVKW-IESNLENFPL-LDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF------GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYS 673
G + Y + V+I + + IVLS+G+ +L+VT+ PIELW+S SRSR E DFF+ +F PF+RTS +II +E + +F + + IF++ +VLKLQK+ E+ + K L+ VC KPL+PEI C +Q+V YWQ + + G YLDH C NP S + C+++ P++ + +GGF K PE+ D A++MT +L N+ + +E+A+ WEK+F+++ +E + P+ +DIAF +E SI+D +E ++GD++ +++SY +MFVY++F L + + +TL + G+ +VL S+ ++ G+F F+GV AT+IIFEI+PFLVLA+G+DNIF+LV T +R+ + E +G + E+AP+ML+S+++++ F+LG LS MPAV FALYAG +++++FL QIT F+++LSLD+ R ++++ D+ CCL KG+ + ++ Y FF+ P LMK+ +++ S V I VGLDPE T+P S+++KYF +LK Y S
Sbjct: 1389 GTVAATYPIPVIIISTGMAIVLSTGILYLQVTTNPIELWASPTSRSRVEKDFFDSNFRPFYRTSQVIIHAKEMDEYNITRFNFTDHLRNNLEMGPIFQKTFLKEVLKLQKKIESLEFVYKEEDDMDYKYNLKTVCNKPLSPEIEECNIQNVLAYWQDDEELLDAEKYDPVGSDGDLPRTWNYLDHFLACANNPTLTSESDKLNIRCMARWGGPVQPYYCLGGFIPKDTSFPENPDYH----QADAVVMTIILNNYDSQSEEEEDVKGLERAMAWEKTFIEFMLEWEEKEKPIYMDIAFNSERSIEDELEKETYGDIMTIVLSYIIMFVYITFTLGQAGSCSFSTFMIESKVTLGLGGVLIVLLSVTASIGVFAFVGVPATLIIFEIIPFLVLAIGVDNIFILVQTYQREPRKDDESHAE---HVGRIVGEVAPSMLVSSISESTCFFLGALSDMPAVQAFALYAGMAIMLDFLMQITCFVSLLSLDISREENRRFDILCCL--KGDKNEESSGDGMIY-----NFFKHLYGPFLMKEWVRALVIIIFFGWACSSVAVLP-KIEVGLDPEITIPDDSFLRKYFSFLKEYLS 3113
BLAST of EMLSAG00000004370 vs. C. finmarchicus
Match: gi|592765111|gb|GAXK01189457.1| (TSA: Calanus finmarchicus comp620364_c3_seq1 transcribed RNA sequence) HSP 1 Score: 355.525 bits (911), Expect = 8.143e-105 Identity = 210/591 (35.53%), Postives = 336/591 (56.85%), Query Frame = 0
Query: 117 GYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPS--NESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQXX--------XXXXXXXXXXXLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQD------TYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGF--KTDKSPESLDSEDILANTSALIMTFLLQNHIEKDR-------VEKAIKWEKSFVKW-IESNLENFPL-LDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF------GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCL-SDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYS 673
G + + + V+I + + IVLS+G+ +L+VT+ PIELW+S SRSR E DFF+ +F PF+RTS +II +E + +F + + IF++ +VLKLQK+ E+ + K L+ VC KPL+PEI C +Q+V YWQ + + G YLDH C NP S + C+++ P++ + +GGF K PE+ D A++MT +L N+ + +E+A+ WEK+F+++ +E + P+ +DIAF +E SI+D +E ++GD++ +++SY +MFVY++F L + + +TL + G+ +VL S+ ++ G+F F+GV AT+IIFEI+PFLVLA+G+DNIF+LV T +R+ + E +G + E+AP+ML+S+++++ F+LG LS MPAV FALYAG +++++FL QIT F+++LSLD+ R ++++ D+ CCL DK E + I FF+ P LMK+ +++ S V I VGLDPE T+P S+++KYF +LK Y S
Sbjct: 1395 GTVAATHPIPVIIISTGMAIVLSTGILYLQVTTNPIELWASPTSRSRVEKDFFDSNFRPFYRTSQVIIHAKEMDEYNITRFNFTDHLRNNLEMGPIFQKTFLKEVLKLQKKIESLEFVYKEEDDMDYKYNLKTVCNKPLSPEIEECNIQNVLAYWQDDEELLDAEKYDPVGSDGDLPRTWNYLDHFLACANNPTLTSESDKLNIRCMARWGGPVQPYYCLGGFIPKDTSFPENPDYH----QADAVVMTIILNNYDSQSEEEEDVKGLERAMAWEKTFIEFMLEWEEKEKPIYMDIAFNSERSIEDELEKETYGDIMTIVLSYIIMFVYITFTLGQAGSCSFSTFMIESKVTLGLGGVLIVLLSVTASIGVFAFVGVPATLIIFEIIPFLVLAIGVDNIFILVQTYQREPRKDDESHAE---HVGRIVGEVAPSMLVSSISESTCFFLGALSDMPAVQAFALYAGMAIMLDFLMQITCFVSLLSLDISREENRRFDILCCLKGDKNE--------ESSGDGMIYNFFKHLYGPFLMKEWVRALVIIIFFGWACSSVAVLP-KIEVGLDPEITIPDDSFLRKYFSFLKEYLS 3119
BLAST of EMLSAG00000004370 vs. C. finmarchicus
Match: gi|592765108|gb|GAXK01189460.1| (TSA: Calanus finmarchicus comp620364_c3_seq4 transcribed RNA sequence) HSP 1 Score: 333.569 bits (854), Expect = 3.138e-97 Identity = 194/538 (36.06%), Postives = 310/538 (57.62%), Query Frame = 0
Query: 117 GYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPS--NESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQXX--------XXXXXXXXXXXLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQD------TYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGF--KTDKSPESLDSEDILANTSALIMTFLLQNHIEKDR-------VEKAIKWEKSFVKW-IESNLENFPL-LDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF------GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCL-SDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKK 620
G + Y + V+I + + IVLS+G+ +L+VT+ PIELW+S SRSR E DFF+ +F PF+RTS +II +E + +F + + IF++ +VLKLQK+ E+ + K L+ VC KPL+PEI C +Q+V YWQ + + G YLDH C NP S + C+++ P++ + +GGF K PE+ D A++MT +L N+ + +E+A+ WEK+F+++ +E + P+ +DIAF +E SI+D +E ++GD++ +++SY +MFVY++F L + + +TL + G+ +VL S+ ++ G+F F+GV AT+IIFEI+PFLVLA+G+DNIF+LV T +R+ + E +G + E+AP+ML+S+++++ F+LG LS MPAV FALYAG +++++FL QIT F+++LSLD+ R ++++ D+ CCL DK E + I FF+ Y P LMKK
Sbjct: 1389 GTVAATYPIPVIIISTGMAIVLSTGILYLQVTTNPIELWASPTSRSRVEKDFFDSNFRPFYRTSQVIIHAKEMDEYNITRFNFTDHLRNNLEMGPIFQKTFLKEVLKLQKKIESLEFVYKEEDDMDYKYNLKTVCNKPLSPEIEECNIQNVLAYWQDDEELLDAEKYDPVGSDGDLPRTWNYLDHFLACANNPTLTSESDKLNIRCMARWGGPVQPYYCLGGFIPKDTSFPENPD----YHQADAVVMTIILNNYDSQSEEEEDVKGLERAMAWEKTFIEFMLEWEEKEKPIYMDIAFNSERSIEDELEKETYGDIMTIVLSYIIMFVYITFTLGQAGSCSFSTFMIESKVTLGLGGVLIVLLSVTASIGVFAFVGVPATLIIFEIIPFLVLAIGVDNIFILVQTYQREPRKDDESHAE---HVGRIVGEVAPSMLVSSISESTCFFLGALSDMPAVQAFALYAGMAIMLDFLMQITCFVSLLSLDISREENRRFDILCCLKGDKNE--------ESSGDGMIYNFFKHYYGPFLMKK 2957
BLAST of EMLSAG00000004370 vs. C. finmarchicus
Match: gi|592765109|gb|GAXK01189459.1| (TSA: Calanus finmarchicus comp620364_c3_seq3 transcribed RNA sequence) HSP 1 Score: 332.028 bits (850), Expect = 1.333e-96 Identity = 192/537 (35.75%), Postives = 312/537 (58.10%), Query Frame = 0
Query: 117 GYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPS--NESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQXX--------XXXXXXXXXXXLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQD------TYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGF--KTDKSPESLDSEDILANTSALIMTFLLQNHIEKDR-------VEKAIKWEKSFVKW-IESNLENFPL-LDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF------GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKK 620
G + + + V+I + + IVLS+G+ +L+VT+ PIELW+S SRSR E DFF+ +F PF+RTS +II +E + +F + + IF++ +VLKLQK+ E+ + K L+ VC KPL+PEI C +Q+V YWQ + + G YLDH C NP S + C+++ P++ + +GGF K PE+ D A++MT +L N+ + +E+A+ WEK+F+++ +E + P+ +DIAF +E SI+D +E ++GD++ +++SY +MFVY++F L + + +TL + G+ +VL S+ ++ G+F F+GV AT+IIFEI+PFLVLA+G+DNIF+LV T +R+ + E +G + E+AP+ML+S+++++ F+LG LS MPAV FALYAG +++++FL QIT F+++LSLD+ R ++++ D+ CCL KG+ + ++ Y FF+ Y P LMKK
Sbjct: 1395 GTVAATHPIPVIIISTGMAIVLSTGILYLQVTTNPIELWASPTSRSRVEKDFFDSNFRPFYRTSQVIIHAKEMDEYNITRFNFTDHLRNNLEMGPIFQKTFLKEVLKLQKKIESLEFVYKEEDDMDYKYNLKTVCNKPLSPEIEECNIQNVLAYWQDDEELLDAEKYDPVGSDGDLPRTWNYLDHFLACANNPTLTSESDKLNIRCMARWGGPVQPYYCLGGFIPKDTSFPENPD----YHQADAVVMTIILNNYDSQSEEEEDVKGLERAMAWEKTFIEFMLEWEEKEKPIYMDIAFNSERSIEDELEKETYGDIMTIVLSYIIMFVYITFTLGQAGSCSFSTFMIESKVTLGLGGVLIVLLSVTASIGVFAFVGVPATLIIFEIIPFLVLAIGVDNIFILVQTYQREPRKDDESHAE---HVGRIVGEVAPSMLVSSISESTCFFLGALSDMPAVQAFALYAGMAIMLDFLMQITCFVSLLSLDISREENRRFDILCCL--KGDKNEESSGDGMIY-----NFFKHYYGPFLMKK 2963
BLAST of EMLSAG00000004370 vs. C. finmarchicus
Match: gi|592810949|gb|GAXK01143619.1| (TSA: Calanus finmarchicus comp525863_c1_seq1 transcribed RNA sequence) HSP 1 Score: 121.709 bits (304), Expect = 2.374e-27 Identity = 87/228 (38.16%), Postives = 128/228 (56.14%), Query Frame = 0
Query: 747 DSQGKICILFSNFMAFHTVLRTSNDFVQAIESTRILSDKFAR--------ENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICW-FLSGKIVIGLYTVTFVSSILIHVTGFISMLGIQXXXXXXXXXXXXCGISVEICIGYLT--SVIMGKRSAEE---VYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
D G + SN MAFHT+L+TS DF A+ R L+D + E + FPYS+F+V+YEQYL+M DTL S+A + + L+ + F+ IV + + I++++ G + I LNAI VNL++ GISVE C SV +G+ E + ++SGI +TN VL F++S IF ++F +Y+ IV+IG HGLI+LPVLLS+
Sbjct: 1245 DDNGVRVVTSSNMMAFHTILKTSEDFYMALSRARELADSIMQAVNNGTEAEKQVNIFPYSVFYVFYEQYLTMWRDTLKSLAISITAIFLVTFVFMGFDIVSSFINLLIIILIVLNMGGLMYWWNITLNAISLVNLVMTVGISVEFCCHTTRAFSVNVGRDRVERATAILTSMGTSVLSGIALTNFFPTMVLAFAKSQIFSIFYFRMYLGIVMIGVAHGLILLPVLLSY 1928 HSP 2 Score: 58.151 bits (139), Expect = 1.312e-7 Identity = 28/69 (40.58%), Postives = 39/69 (56.52%), Query Frame = 0
Query: 675 GPPVYFVVNSTN--MDLATVKSQNRIC-GSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSWS 740
GPPVYFVVN+T +D + QN++C G GC S + W P+ T +AT+ WID Y +W+
Sbjct: 2286 GPPVYFVVNNTQGQLDFSLPHDQNKLCLGLPGCQEDSLAGQIFNWQKVPEKTYIATAPMPWIDGYITWA 2492
BLAST of EMLSAG00000004370 vs. C. finmarchicus
Match: gi|592924582|gb|GAXK01033833.1| (TSA: Calanus finmarchicus comp82933_c0_seq2 transcribed RNA sequence) HSP 1 Score: 115.546 bits (288), Expect = 3.737e-25 Identity = 156/698 (22.35%), Postives = 295/698 (42.26%), Query Frame = 0
Query: 336 DILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFVKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYF-------LMFVYVSFALTDFRNKKYFGITLAIAGIFMVLGSILSTTGLFG--------FIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCL-------SDK---------GEIDVDNP-KSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQ-------NRICGSAGCDP-------YSFQTAMKLWSTKPDLTTLATSGQS---------------WIDDYFSWSNDC------CMVDSQGKICILFSNFMAFHTVLRTSNDFVQAIESTRILSDKFARENNITSF-PYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSGKIVIGLYTVTFVSSILIHVTGFISMLGIQXXXXXXXXXXXXCGISVEICIGYLTSVIMGKRSA--EEVYNDQAGILMSGIH--ITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSFF 961
+ + +AL +T+ L E ++ + WE SF+ + + +N P + I + ++++ +E N++ +I YF ++F ++ +TD+ K + G+F V+ +IL++ FG FIG+ PFL+L +GID+ FV++ RR V +G E A ++ I+++T +F++G ++ P V F +Y G ++ +L IT F +++ K + L CC+ K G I+ D+P + N + FF + L K K V+ + I L N+ GL+ + SY Y+E ++ P VV S +D + V+ Q +++ + DP SF ++ W PD L + ++ D + C C + I+ + F+ ++ S D + ++ R + A + N+T F PY I Y++Q+L + T+ + + M+ I V L+ + SI + V GF++ + L++I +NL++ G SV+ +++ M + V N G+ + + ++ ++GV L + S IF +F V++ ++ +G +HG+ +LPVLLS F
Sbjct: 1095 NTIDKAAALSLTYFLDAQ-EDWQIARGSAWEASFLATVSA--QNLPNIKITRFSSLTLEQELEENTNS-----VIPYFSLNIGVMIVFCILTCMMTDWVKSK------PLLGLFGVISAILASISAFGMVMYLGMDFIGINLA------APFLMLGIGIDDTFVMLAAWRRT-----SSHDPVPVRMGNCYREAAVSITITSVTDMLSFWIGVITPFPCVKIFCVYTGACVIFTYLWHITFFGGCMAVAGYAEKQNRHALSCCVVLPKSQAGSKGFFYNVFCSGGINKDDPFNPKDNKDNGMMVFFRDVIGNWLNKPY-AKALVLTIFVIYLGFASWGVTNLQEGLEKKRLSRFDSYSVDYYEVEDEFFREYPFRINVVVSGALDYSQVEVQKDMEDLLSKLENTTYIDPLYTESWLRSFLDYVERWKDYPDYYELKVDDEQNFIKTLKDVYLINTPFVQDIDFDTTTCPGNIEDCKETPEALEHIVGARFLLQGHQIKNSQDEAKFVQELRDICH--ASKYNVTVFHPYFI---YFDQFLVVLPTTIQCVVIAAVVMMFISLIFIPNPVCSLWVAFAIISIELGVLGFMTFWHVNLDSISMINLIMCIGFSVDFA-AHISYHYMDSEGTPDDRVRNSLYGLGLPIVQGAVSTILGVIGLMIAPSYIFVTFFKMVFL-VICLGALHGIFLLPVLLSIF 3089
BLAST of EMLSAG00000004370 vs. C. finmarchicus
Match: gi|592924583|gb|GAXK01033832.1| (TSA: Calanus finmarchicus comp82933_c0_seq1 transcribed RNA sequence) HSP 1 Score: 115.546 bits (288), Expect = 3.896e-25 Identity = 156/698 (22.35%), Postives = 295/698 (42.26%), Query Frame = 0
Query: 336 DILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFVKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYF-------LMFVYVSFALTDFRNKKYFGITLAIAGIFMVLGSILSTTGLFG--------FIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCL-------SDK---------GEIDVDNP-KSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQ-------NRICGSAGCDP-------YSFQTAMKLWSTKPDLTTLATSGQS---------------WIDDYFSWSNDC------CMVDSQGKICILFSNFMAFHTVLRTSNDFVQAIESTRILSDKFARENNITSF-PYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSGKIVIGLYTVTFVSSILIHVTGFISMLGIQXXXXXXXXXXXXCGISVEICIGYLTSVIMGKRSA--EEVYNDQAGILMSGIH--ITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSFF 961
+ + +AL +T+ L E ++ + WE SF+ + + +N P + I + ++++ +E N++ +I YF ++F ++ +TD+ K + G+F V+ +IL++ FG FIG+ PFL+L +GID+ FV++ RR V +G E A ++ I+++T +F++G ++ P V F +Y G ++ +L IT F +++ K + L CC+ K G I+ D+P + N + FF + L K K V+ + I L N+ GL+ + SY Y+E ++ P VV S +D + V+ Q +++ + DP SF ++ W PD L + ++ D + C C + I+ + F+ ++ S D + ++ R + A + N+T F PY I Y++Q+L + T+ + + M+ I V L+ + SI + V GF++ + L++I +NL++ G SV+ +++ M + V N G+ + + ++ ++GV L + S IF +F V++ ++ +G +HG+ +LPVLLS F
Sbjct: 1095 NTIDKAAALSLTYFLDAQ-EDWQIARGSAWEASFLATVSA--QNLPNIKITRFSSLTLEQELEENTNS-----VIPYFSLNIGVMIVFCILTCMMTDWVKSK------PLLGLFGVISAILASISAFGMVMYLGMDFIGINLA------APFLMLGIGIDDTFVMLAAWRRT-----SSHDPVPVRMGNCYREAAVSITITSVTDMLSFWIGVITPFPCVKIFCVYTGACVIFTYLWHITFFGGCMAVAGYAEKQNRHALSCCVVLPKSQAGSKGFFYNVFCSGGINKDDPFNPKDNKDNGMMVFFRDVIGNWLNKPY-AKALVLTIFVIYLGFASWGVTNLQEGLEKKRLSRFDSYSVDYYEVEDEFFREYPFRINVVVSGALDYSQVEVQKDMEDLLSKLENTTYIDPLYTESWLRSFLDYVERWKDYPDYYELKVDDEQNFIKTLKDVYLINTPFVQDIDFDTTTCPGNIEDCKETPEALEHIVGARFLLQGHQIKNSQDEAKFVQELRDICH--ASKYNVTVFHPYFI---YFDQFLVVLPTTIQCVVIAAVVMMFISLIFIPNPVCSLWVAFAIISIELGVLGFMTFWHVNLDSISMINLIMCIGFSVDFA-AHISYHYMDSEGTPDDRVRNSLYGLGLPIVQGAVSTILGVIGLMIAPSYIFVTFFKMVFL-VICLGALHGIFLLPVLLSIF 3089
BLAST of EMLSAG00000004370 vs. L. salmonis peptides
Match: EMLSAP00000004370 (pep:novel supercontig:LSalAtl2s:LSalAtl2s22:157610:161978:1 gene:EMLSAG00000004370 transcript:EMLSAT00000004370 description:"maker-LSalAtl2s22-snap-gene-1.32") HSP 1 Score: 1951.02 bits (5053), Expect = 0.000e+0 Identity = 962/962 (100.00%), Postives = 962/962 (100.00%), Query Frame = 0
Query: 1 MYALNFSFVSLIPEYLFCQLIIILNSKSCACLDXKQACPKLDADEYKEILTLKNEYMNFPIAYSVLIVILLLMLLVGIFLIAIKIKAKNRISSETQEESRKESIGWLLFQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDKITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFVKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYFGITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSWSNDCCMVDSQGKICILFSNFMAFHTVLRTSNDFVQAIESTRILSDKFARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSGKIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIMGKRSAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSFFY 962
MYALNFSFVSLIPEYLFCQLIIILNSKSCACLDXKQACPKLDADEYKEILTLKNEYMNFPIAYSVLIVILLLMLLVGIFLIAIKIKAKNRISSETQEESRKESIGWLLFQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDKITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFVKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYFGITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSWSNDCCMVDSQGKICILFSNFMAFHTVLRTSNDFVQAIESTRILSDKFARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSGKIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIMGKRSAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSFFY
Sbjct: 1 MYALNFSFVSLIPEYLFCQLIIILNSKSCACLDXKQACPKLDADEYKEILTLKNEYMNFPIAYSVLIVILLLMLLVGIFLIAIKIKAKNRISSETQEESRKESIGWLLFQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDKITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFVKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYFGITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSWSNDCCMVDSQGKICILFSNFMAFHTVLRTSNDFVQAIESTRILSDKFARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSGKIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIMGKRSAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSFFY 962
BLAST of EMLSAG00000004370 vs. L. salmonis peptides
Match: EMLSAP00000008403 (pep:novel supercontig:LSalAtl2s:LSalAtl2s513:547002:563743:1 gene:EMLSAG00000008403 transcript:EMLSAT00000008403 description:"maker-LSalAtl2s513-augustus-gene-5.4") HSP 1 Score: 396.741 bits (1018), Expect = 2.314e-121 Identity = 232/597 (38.86%), Postives = 354/597 (59.30%), Query Frame = 0
Query: 22 IILNSKS-CACLDXKQACPKLDADEYKEILTLKNEYMNFPIAYSVLIVILLLMLLVGI-----FLIAIKIKAK----NRISSETQEESRK----ESIG-----WLLFQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQ-EMFYQVLKLQKEIEKIITED-KITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDR-GHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEK-------AIKWEKSFV----KWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLF 581
I +N KS C+C D + +C ++ L N +N +I ++ ++ VG+ F+ I+A N S SR ++ G WL+ FF + G FC+ Y V V+ + ++ + L +G+FWL+VT++PIELW+S SRSR+E DFF+E F PF+R + +II N L F+Y +L+G+ F IF + E +L+LQKEIEKI T+D K+ L+D+C+ PL P +C +Q++W+YWQ + ND+ H DTYLDH C NP + + T+M QSC+SKG +P++ FV+GGF + + + + + AN A+++TFL+ N+ + R + A++WEK+F+ KWI+ N EN +DIAF +E SI D I + GD+ + ISY +MFVY++ +L D + K F ITLAI G+ +V+ S+ ++ G+FGFI AT+IIFEI+PFLVLA G DNIF+LV A+R E E + IG + ++ P+ML+++ T++ F+LG +S MPAV FALYAG +LLI+F QIT FI++++LD+ R + D+F
Sbjct: 35 IRVNGKSPCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRADCTDMNDTGSSKTFFSRTINSIKNAGEDLDEWLII--FFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKN---LSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQAN--AVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQ-NPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQR--YGPESTETHQE-YIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIF 620 HSP 2 Score: 89.7373 bits (221), Expect = 1.994e-18 Identity = 50/140 (35.71%), Postives = 87/140 (62.14%), Query Frame = 0
Query: 754 ILFSNFMAFHTVLRTSNDFVQAIESTRILSDKF--ARENNITS-------FPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEIC 883
++ SNFM FHT+L++S D+ +A+ +R L+ + A N+T+ FPYSIF+V+YEQYL+M DT+ S+ +++ ++ + +G +++ L + + I ++ G + + I LNAI VNL++A GIS+E C
Sbjct: 770 VIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFC 909
BLAST of EMLSAG00000004370 vs. L. salmonis peptides
Match: EMLSAP00000001950 (pep:novel supercontig:LSalAtl2s:LSalAtl2s1345:18618:29195:1 gene:EMLSAG00000001950 transcript:EMLSAT00000001950 description:"maker-LSalAtl2s1345-snap-gene-0.7") HSP 1 Score: 400.208 bits (1027), Expect = 2.543e-120 Identity = 236/650 (36.31%), Postives = 364/650 (56.00%), Query Frame = 0
Query: 106 WLLFQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMF-YQVLKLQKEIEKIIT-EDKITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEK---AIKWEKSFVKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSWSND--CC 744
WL+ FF G FC+KY + V+I + I I L +G+FWL VT++PIELW+S +SRSR E DFF++ F PF+R + +I+ N L FKY++ G+ +F IF +E F + +L+LQK IE I T E+ ITL+D+C+ PL P +D G ++ +G GF+P F P++ + A ++++ N + ++K A++WEK++ +DIAF +E SI+D + ++GD+ + +SY +MF+Y++F+L + K F ITL + G+ +VL S+ ++ G+FGFI V AT+IIFEI+PFLVLAVG DNIF++V T +R +E +G + E+AP+ML++++T++ F+LG +S MPAV FALYAG +LLI+FL Q+T FI+++SLD+ R D+ CC+ + N Y+ F+ + +P +MK+ V+ +V+++ +L T I VGLD + +MP S+V KYF +++ Y SVGPPVYFVV+S+N+DL+ QN+ CG AGC S + + LWS +P+ T +A QSWIDDY +W+ D CC
Sbjct: 362 WLV--NFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKN---LSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENGITLKDICHAPLEP-------------------------ISDGG----------------IPVQPYYMLG------GFIPENEPF----------PQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAY------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVE---HVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYK-----LFKHFYAPFVMKEW-VRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTIDDSCC 928 HSP 2 Score: 85.8853 bits (211), Expect = 3.991e-17 Identity = 52/140 (37.14%), Postives = 84/140 (60.00%), Query Frame = 0
Query: 754 ILFSNFMAFHTVLRTSNDFVQAIESTRILSDKFA---------RENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEIC 883
++ SNFM FHT+L+T D+ +A+ R LS + + + FPYSIF+V+YEQYL+M +DT+ S+ L++ ++ + L+G + + V ++ ILI++ G + I LNA+ VNL++A GISVE C
Sbjct: 1098 VIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFC 1237
BLAST of EMLSAG00000004370 vs. L. salmonis peptides
Match: EMLSAP00000008727 (pep:novel supercontig:LSalAtl2s:LSalAtl2s542:206164:232722:1 gene:EMLSAG00000008727 transcript:EMLSAT00000008727 description:"maker-LSalAtl2s542-augustus-gene-2.8") HSP 1 Score: 146.362 bits (368), Expect = 5.323e-36 Identity = 204/918 (22.22%), Postives = 388/918 (42.27%), Query Frame = 0
Query: 113 FRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQ-----------KEIEKIITEDKITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFVKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDV--LVVIISYFLMFVYVSFALTDFRNKKYFGITLAIAGIFMVLGSILSTTGLFGFI---GVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCC----------------LSDKGEIDVDNP-KSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW---SNDCCMVD--------SQGKICILFSNFMAFHTVLRTSNDFVQAIESTRIL-----------SDKFARENN----ITSFPYSIFH---VYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSGKIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVE----ICIGYLT---SVIMGKRSAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSFF 961
F K+G K+ Y +I ++ + ++G L S+P L+S ++ S E + E +F T+ PS S + +F + K+ I R +++ ++ L KE +++ + K+ +D+C A C W+ N D G T ++ + P T G + F GG L ++ + + +A+ + + L + KD +E+ KWE F+ +E+ ++F + +A + ++++ +E+N++ + + I + F ++ +TD+ K + G+F V+ +I++ FGFI GV I PFL+L +GID+ FV++ + RR + V + + T + A ++ I+++T +F++G ++ P+V F LY G + +L IT F +++ KS + L C + G I D+P + N + I F YV+ + K V+V L I NI GL+ + SY +++E Y+ P VV S + + + ++ QN + + +K + + T +SW D+ + + D +D S K L S F + + S D ++I ++R L KF +E +++ ++FH +Y++Q+L + T+ I M+ I V L+ + SI + V GF+++ G+ L++I +NL++ G SV+ I Y++ S +R + +Y G+ + I+ ++GV L + S +F +F V++ ++V+G +HGL+VLP+LLS F
Sbjct: 17 FSKVGIIVGKHPGYFVIIPLLLTALAATGFQRLHFQSDPEYLFSPSDGESHYE----RKVLETYFNTNYSDFEPSRSSRVGRFGKLIISSKDN--GSILRMKIWEEIESLNFLIENFEVFSLKECDEVKSSMKLNFKDLC----ASHQGKC--------WR--------NKILDLGKHITEIESKEIKLTFPLWFDPETFQGYTF----------NFFFGGV-------ILRNDSTIKSVTAVSLFYFLNSQTSKD-IERGAKWEGMFLATVEA--QSFSYIKVARFSSLTLEVELENNTNSVIPFFALNIGIMIAFCIITCMMTDWVKSK------PLLGLFGVISAIMAXLFSFGFIIYCGVPFIGINLA-APFLMLGIGIDDTFVMLGSWRRTSV-----HETVPARLAQTYRDAAISITITSITDMLSFWIGIITPFPSVRIFCLYTGACVAFTYLWHITFFGGCMAIAGYAEKSNRHSLTCLTVIPKSKAESKNWLYRIFCSGGISPDDPFNKKDNAENAIMVIFRDYVARAINNGY-FKIFVLVFFTFYLVIAGWGVSNIQEGLERKKLARYDSYSVEFYEMEDTYFREYPYRVNVVLSGHFNYSNLQVQNDV-----------EKLLKKLENSSFVDHVYT--ESWYRDFLDYVKRNKDFAELDISTEENFISTLKEVYLGSGFTHYVKDVHFSTD-NKSIIASRFLIQGTKIYNTNDEKKFVQELRYVCLTSNYNVTVFHPYFIYFDQFLMVLPTTIQCITVAAFVMMFISLIFIPNPVCSLWVAFSIISIEVGVVGFMTLWGVGLDSISMINLIMCIGFSVDFSAHISYHYMSCEKSFTDKERIRDSMY--ALGLPIVQGAISTILGVVGLALAPSYVFITFFKMVFL-VIVLGALHGLLVLPILLSIF 858
BLAST of EMLSAG00000004370 vs. L. salmonis peptides
Match: EMLSAP00000003602 (pep:novel supercontig:LSalAtl2s:LSalAtl2s197:152115:159124:1 gene:EMLSAG00000003602 transcript:EMLSAT00000003602 description:"maker-LSalAtl2s197-snap-gene-1.29") HSP 1 Score: 132.494 bits (332), Expect = 8.446e-32 Identity = 217/923 (23.51%), Postives = 399/923 (43.23%), Query Frame = 0
Query: 94 ETQEESRKESIGWLLFQTFFRKLGYFCSKYAVYVLICNGI-IFIVLSSGVFWLKVTSEPIELWSSTNS----RSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDKITLQDVCYK-----PLAPEIPSCLLQSVWNY-WQGSNSS-FNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQ-NHIEKDRVEKAIKWEKSFVKWIESNLENFPLLD------IAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYFGITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARR-KLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKY--VSPVLMKKLTVKFSVMVLIAITLSITLVFTLN-IPVGLDPESTMPKGSYVKKYFEWLKLYYS-VG--PPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTT----------LATSGQSWIDDYFSWSNDCCMVDSQGKIC------ILFSNF-MAFHTVLRTS-NDFVQAIESTRILSDKFARENNITSFPYSIFHVYYEQYLSMKT-DTLVS-----IAYVLLTMLLICWFLSGKIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVE----ICIGYLTS--VIMGKRSAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
T E I W+ +Q G +KY+ YV I + IFI + G S+P ++W +S ++K D ++ T I +I S + L+ + N +Y KL I + T +D+C+K P++ PS + +++ N W S S F + +++ + + + LT E+ S + F P ++G + + L AL++++ ++ N +K+ + WEKS ++ ++ N+ D + + + ++ DV + I Y ++FVY+ F L + ++ LA+ GI V S+ G+F + V AT + I+PF++L +GID++FV+V ++ K E E ++DS IG ++ A+ +++LT AF +G S++PA+ F LY+ + + +T F+ +D +R++S + C+ KS + T +F E S VL+ L + + +++ I +S V+ L I DP+S + S + YF+ + ++ +G P ++++N N + K + S + S +T K +S + TT L TS F W+ SQ +C + S F + F + +T D +Q+++ + +K E N FP++ QY ++ T D ++S I L+T+ + FL + +Y + + +I VTG++ G+ ++ AV L V+ G++V+ I GY+ S G++ + + +L G I+ + +L S S+I F FF ++ +V+ G HGLI LPVLLSF
Sbjct: 10 HTCHERVNHGINWIFYQ-----YGMIVAKYS-YVFIGLSLGIFIASTLGFIDYVTESDPTKIWLPQDSYYVQNTKKIKDLNSDAVNA--ATVIQVIVESEVNILRAKELNAVY-------------------KLHSSIINLKAPSNETFKDLCFKERVTVPISTP-PSEICRALANAEWLCSAKSIFEIWTSDESSKEASIIAQLTD--EDILDALSQDLAISKLFRRPFRP-----IIGS-------KMFNDNGTLKGAKALLLSYSIKTNSSDKNGIPI---WEKS----VKEHVFNYSFGDESSNLSVTLFSSSIFRAEFQNGMENDVQLFIFGYLIVFVYIIFNLGEMNTLEH-KFYLAVVGIACVGMGYASSVGIFQLLSVYATPMN-SILPFMLLGIGIDDMFVIVQASKNVKQNDDEEGENKMDSYIGNIMKSAGXAITVTSLTDILAFGIGGFSQLPALRNFCLYSSAGIFFVYFYIMTFFLGWFVIDARRVESHRDACLPCIIK---------KSSWVPCYTRKSFAEXLFSCSGVLIDSLFFR-GLAIIVTIVVSGFGVYGLTLIEPKFDPKSYINPESKLLSYFKASEQHFQKLGGIPGQFYILNPNNSLVEIEKVYEELKNSEFIEENSLRTFHKAFSKTINSTTNFQYSSLTNFLYTSRVP-----FDWA--VKFKASQKPVCGDTTEDVKLSAFVLYFQHIKKTRVQDQIQSMKKIYQIGEKIEGERNGLIFPHAT------QYSNLITLDIILSELTRNILLALMTVFIAALFLLAXALTSIYVLLSILLSIIDVTGYMYFWGVSIDTASAVLLTVSLGLAVDYSAHIAHGYIHSSKSSRGEKVKDSLTKVGPAVLSGG--ISTFLAFILLANS-SSIVFTTFFKIFFLVVLFGLYHGLIFLPVLLSF 855
BLAST of EMLSAG00000004370 vs. L. salmonis peptides
Match: EMLSAP00000010537 (pep:novel supercontig:LSalAtl2s:LSalAtl2s6:1415448:1420769:-1 gene:EMLSAG00000010537 transcript:EMLSAT00000010537 description:"maker-LSalAtl2s6-augustus-gene-13.12") HSP 1 Score: 125.176 bits (313), Expect = 2.256e-29 Identity = 157/675 (23.26%), Postives = 282/675 (41.78%), Query Frame = 0
Query: 355 EKDRVEKAIKWEKSFVKWIESNLENF-PLLDIAFIAEMSIQDAIES--NSHGDVLVVIISYFLMFVYVSFALTDFRNKKYFGITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVD-------------NPKSRFNYQKTIS----TFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLY---YSVGPPVYFVVNSTNMDL--ATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW--------------SNDCCMVDS--------------------QGKICILFSNFMAFHTVLRTSNDFVQAIESTRILSDKFARENNITSFPYSIFHVYY---EQYLSMKTDTLVSIAYVLLTMLLICWFLSGKIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVE----ICIGYLTSVIMGKRSAEEVYNDQAGILMSGIH--ITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSFF 961
E+ R ++WEK F+ + F P L+I + +E+ NS L + + ++F VS ++D K + AG+F + ++ G ++GV+ + F PFL+L +G+D+ FV++ + RR + + +G E A ++ +++LT +F G ++ P V F LY G S+ + +T F AIL++ + K+ +FC + V+ NPK N FF + L+ + K V++L + + NI GL+ ++ SY KY+ Y YS V S DL + K+Q RI L++ + + QSW+ D+ + S + VD+ K I+ S F+ + S + R + ++F+ + S+FH Y+ +QYL++ T+ I L M++I +FL +V + + SI + V G+++ G++L+ + +NL++ G SV+ IC Y+T E + + G+ + I + ++GV L F+ S +F +F V++ ++V+G +HGLI+LPVLLS F
Sbjct: 222 EEWRDNLGLRWEKKFLDALREIGPYFAPDLEIGMFVSNTPAWEMEASKNSVTSTLCINVVIMVVFSLVSCLMSDATKSKPL---VGFAGLFSATIATIAGFGFACYVGVEFISLNFA-APFLLLGIGVDDTFVILSSWRRS-----SSNLSIPERMGRCYSEAAVSITVTSLTDFFSFMAGVVTPFPCVRIFCLYTGISVAFIYFWHLTLFGAILAVSGRAEKNNLHGMFCIKVIPKSLAVNKSWLTRTFMTGGTNPKDPHNPDDNKDHAGMVFFRDNMG-RLLSRTWFKSLVLLLFGAYIVVACWGVTNIEEGLEKQNMANYDSYSVKYYSMDDSYFREYSYTISVIITSASNERDLLYSDSKTQARI-------------ERVLYALENSXFIEKAATQSWLRDFLDYIKRNENYEDIILPVSTEMEFVDTLSNVYLSDPSNPLRLDVAYNHNKNGIIASRFLIQGRNILNSYMEQSMVAELRDICNQFSTPD----ISISVFHPYFIYIDQYLAIAPQTVQCILVTSLVMMIISFFLIPSLVCSFWVAFSIISIELGVIGYMTWWGVRLDGVALINLIMCIGFSVDFSAHICYHYITDT-ESSSPDERIRSSLYGLGLPIIQGATSTILGVLGLAFAPSYLFVTFFKMVFL-VIVLGGLHGLIILPVLLSLF 867
BLAST of EMLSAG00000004370 vs. L. salmonis peptides
Match: EMLSAP00000007725 (pep:novel supercontig:LSalAtl2s:LSalAtl2s44:25674:28922:-1 gene:EMLSAG00000007725 transcript:EMLSAT00000007725 description:"maker-LSalAtl2s44-augustus-gene-0.13") HSP 1 Score: 94.7449 bits (234), Expect = 6.169e-20 Identity = 138/615 (22.44%), Postives = 251/615 (40.81%), Query Frame = 0
Query: 403 GDVLVVIISYFLMFVYVSFALTDFRNKKYFGIT--LAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKG------EIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSWSNDCCMVDS----------------QGKICILFSNFMAFHTVLRTSNDFVQAIES--------------TRILSDKFAR------ENNITS----FPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSGKIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVI----------MGKRSAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLS 959
GDV ++ I Y ++F YV L F + G LAIAGI V+ I+ + G+ +G + + I+PFL+L +GID++F+++ L E VD G T+ A+ +++LT AF +G S +PA+ +F +++ + + Q+T F+A + D KRI S + C+ K EI D + I F+ + +K VKF ++++ S+ I DP +P +Y+ +FE ++S + V +DL+ D + ++ ++ D+ S SW +Y + + + + Q K L N A ++S F + ES ++I R N+TS FP S + +E + + +I + + + ++ W + V + V ++ V+G + G+ ++ + + N L+ IS+ +C+ Y T V +R + + N ++ G I+ + +L S S++F FF V+ +V G HGL+ LPV+LS
Sbjct: 394 GDVKILGIGYSIVFFYVLLMLGKF---DWVGXRXYLAIAGIISVVFGIVFSIGICSAMGFFWSPM-HSILPFLLLGIGIDDMFIII-QCWNTLNPYEKASSSVDKF-GYTMRHAGVAITVTSLTDIVAFGIGGTSXLPALRSFCIFSAVGIAAIYYFQVTFFVAWMVFDEKRISSGRNGCCPCIEVKKVKKNTEEIMEDMEVESLSIMSKIFRFYASH-----LKFKPVKFLIILITMGFTSLGAYGNYLIEQKFDPIWFIPPHTYLSDWFEANTKWFSDKGGFFVNVYVYEVDLSV-------------DLMELERIIRAIESQSDII---DSVNSWTTNYIKYVDTHGLAEGTLYERITQFLHSPMGLQYKRNFLTVNGTADFDCGKSSTGFFNSNESIWYFNFNYKVLESDSKIKISAMNRIKDILNSANLTSSGRIFPLSQGYSMWETDEIIGYELYKNIIFAFVAVFIMTWIVISNFVASFLVLFAVMLTVLDVSGIMHFWGLTIDTV-SCNFLI---ISIGLCVDYSTHVAHRFLIEAEGSRDQRIVKALTNIGPAVMNGG--ISTFLAFCLLCGSSSHVFI-TFFKVFFLVVTFGLFHGLVFLPVILS 974
BLAST of EMLSAG00000004370 vs. L. salmonis peptides
Match: EMLSAP00000012098 (pep:novel supercontig:LSalAtl2s:LSalAtl2s867:155984:163315:1 gene:EMLSAG00000012098 transcript:EMLSAT00000012098 description:"maker-LSalAtl2s867-snap-gene-0.32") HSP 1 Score: 81.2629 bits (199), Expect = 8.946e-16 Identity = 146/672 (21.73%), Postives = 301/672 (44.79%), Query Frame = 0
Query: 321 GGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFVKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYFGITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARR--KLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGT-LSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITL-SITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDL--ATVKSQ-----NRICGSAGCDP---------YSF-------QTAMKLWSTKPDLTTLATSGQSWIDDYFSWSNDCCMVDSQGKICILFSNFMAFHTVLRTSNDFVQAIESTRILSDKFARENNITS--FPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSGKIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVE----ICIGYLTSVIMGKRSAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLS 959
GG D+ ++ +I+ AL ++++L + + + A W + +++++ N+ P L++ + SI+ SN + + +S L+ Y + ++ N +++ G ++ +I + G +IGV+ I V F++L VG+D+I+V++ + RR +LLS+ R + + EE A ++ I++LT +F +G+ P+V F LY+G + ++ +T F +L++ ++++L K +ID+ + + F++ ++ F+E + P ++ K+ K V+ L L S L+ N GLD S++ Y++ Y+ P + VV + +D ++V+ Q N+I S + F QT W+ + T + + + +V + K IL S +R S++ ++ + D E I + FP +++Q+L + T+ S++ + ++LI + L IV L+ + SI I V GF+ + I L+ I + L++ G S++ + +++ I + G + ++ ++GV+ L F S I F + + ++++G +HG ++LPVLLS
Sbjct: 194 GGITVDE-----NNTNIVRKIQALRLSYIL----DPSQSKYANLWLSALLEFLD-NIST-PHLNVYKMTTKSIEVEFASNVDSAIDFLPLSVALLISYNIWNALNWNNPILGKPYVSLVGSLNIVVAIGAAWGFLMYIGVEWISINLASV-FILLGVGLDDIYVILFSWRRTSELLSVPER-------LSLCYEEAAVSITITSLTNIVSFVMGSAFPVFPSVWIFCLYSGIGIFFIYIWTLTFFGGVLAISGYTEETERL------KKKQDIDIVDSEIGFDF---LNHFYESTL-PNILNKVYAKVIVIALYLTYLTSFILIILNNTKEGLDRSKLSRYDSFLSSYYKAEDNYFRQNPYRFQVVFTEALDYSNSSVRQQISNFINKIQNSKYVSQNEQFKENWLHVFDQIVEKKQTIFTGWTLENSEHRFITKLSETLHRHHLPEIEENIVFNHNKTKILASRIFLQSEKVRNSHEEKLMMQDLYEILDSAPFETIIFNPLFP------FFDQFLQVLPSTIYSVSITAIVVILITFILIPNIVFTLWVTIALVSIEIGVLGFMVIFEINLDIISMICLIMCVGFSIDYSAHVSYHFVSMNIRNNSIRLKSXLXAYGPPIVQSAVSTMLGVTGLFFLPSYI-IRSFSLLLVIVILLGVIHGTVLLPVLLS 829
BLAST of EMLSAG00000004370 vs. L. salmonis peptides
Match: EMLSAP00000006144 (pep:novel supercontig:LSalAtl2s:LSalAtl2s335:81464:114163:-1 gene:EMLSAG00000006144 transcript:EMLSAT00000006144 description:"maker-LSalAtl2s335-augustus-gene-1.6") HSP 1 Score: 77.411 bits (189), Expect = 1.320e-14 Identity = 77/291 (26.46%), Postives = 121/291 (41.58%), Query Frame = 0
Query: 695 QNRICGSAGC-DPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSWSNDC----CMVDSQGKICILFSNFMAFHTVLRTSNDFVQAIESTRILSDKFARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSGKIVIGLYTVTFVSS---------------ILIHVTGFISMLGIQLNAILAVNLLVACGISVE----ICIGYLTSVIMGKRSAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSFF 961
+NR+ G +P F + W + D T + S +++ W +D V I F H +N V + R + KF + + +FP + Y+EQY+S++ VS+ V+ G +V F S LI G + LGI +A+ AV L++A GI VE ICIG++TSV R + G ++ +G+ +L FS + F YFF V S++++G +GL+ LPVLL F
Sbjct: 715 RNRLVDIHGMINPSGFYNYLXAWVSN-DATAYSFSQANFVPTPKKWMHDPRDSDLRVPKSQPIAYAQIPFYLSHVGGPDTNVMVSTVSQIREICSKFEEQRGLPNFPSGVPFSYWEQYISLRFWLAVSLGAVMAG------------TFGTVSVVFASPWLGTVVVVVLTTILVQLIGAMGLV--LGIHFSAVPAVVLILAVGIGVEFTLHICIGFVTSVGSKNRRIVLSLKHMFTPVFHGA-VSTFLGIIMLAFSHFDFVFRYFFLVLSSLILLGLFNGLVFLPVLLLMF 989 HSP 2 Score: 62.003 bits (149), Expect = 7.887e-10 Identity = 47/173 (27.17%), Postives = 75/173 (43.35%), Query Frame = 0
Query: 507 IGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKG------EIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYS 673
IG L ++L++ + AF + +PA+ +FA A + N + F AI++ DLKR+ +++ DLFCC S K E D N + RF Y K +F + K VK V+V I L+ + GLD +PK + + + Y+
Sbjct: 436 IGEVLSRAGMSVLLTAVCNIAAFVSAAVIPVPALRSFAFQAAILVACNLPCSLILFPAIMTWDLKRVSARRSDLFCCYSAKDPESNKLEDDKLNVR-RFKYDKWTLKYFASRYYGQWISKTPVKILVLVTTTILTCGGLIGLARMEDGLDLTEIVPKNTSFHDFLQAQNKYFG 607
BLAST of EMLSAG00000004370 vs. L. salmonis peptides
Match: EMLSAP00000005221 (pep:novel supercontig:LSalAtl2s:LSalAtl2s276:209809:212602:-1 gene:EMLSAG00000005221 transcript:EMLSAT00000005221 description:"maker-LSalAtl2s276-augustus-gene-2.14") HSP 1 Score: 70.0922 bits (170), Expect = 1.624e-12 Identity = 86/326 (26.38%), Postives = 152/326 (46.63%), Query Frame = 0
Query: 352 NHIEKD--RVEKAIKWEKSFVKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFR--NKKYFGITLAIAGIFMVLG-SILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVF------TLNIPVGLDPESTMPKGSYVKKYFE 666
+++E D R A WEK NL NF QD I ++ G + V + + L+ +Y +DF N++ + L + G FMV+G +I S+ GL IG+ + I+PFL+L +G+D++F+++ + LS + +E+ + I + ++ ++ +++LT AF + + + +P + F L + + +T FIA +LD +RI+ K L+ K V KS + + ++KY ++ L S ++L I+L LVF T NI DP + M + SY K+ E
Sbjct: 7 DYVEGDLPRDWVAEDWEK--------NLINF-------------QDEIVTSIDGGMYVFGVGFLLILIYSLLVTSDFHPVNQR---VMLLLLG-FMVIGMAIGSSFGLGFHIGIIYADL-HPIIPFLLLGIGVDDLFIIIKSTDN--LSQKEKELPLKERIALVVQHSGVSITVTSLTDLVAFLISSTTSIPLLRAFCLSVALGISFLYFFVVTFFIAWYTLDERRIEEGKAFLWFT---KRVHSVPPKKSTWTHN-----LYKKY----YVEYLFAIPSQLILGGISL---LVFGFGIFGTFNIQQDYDPITYMRQNSYQVKFIE 289
BLAST of EMLSAG00000004370 vs. SwissProt
Match: gi|449081276|sp|O35604.2|NPC1_MOUSE (RecName: Full=Niemann-Pick C1 protein; Flags: Precursor) HSP 1 Score: 399.823 bits (1026), Expect = 3.743e-120 Identity = 239/677 (35.30%), Postives = 372/677 (54.95%), Query Frame = 0
Query: 92 SSETQEESRKESIGWLL---FQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIIT---EDKITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHI-EKDRVEKAIKWEKSFVKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSWSNDCCMVDSQGKICILFS 757
SS+ E S + +G + F K G FC + ++ + V SSG+ +++VT+ P+ELWS+ +S++R E ++F++HF PFFRT LII N S Y G + F +E+ +QVL LQ IE I + +TLQD+C PL+P +C + SV NY+Q S++ + + +D Y H CV P ++ ++ + CL P+ V+GG+ N +AL++TF + N+ + +R+++A WEK F+ +++ N +N P L I+F AE SI+D + S+ DV VIISY +MF+Y+S AL ++ I+L IAGI +VL S+ + G+F ++G+ T+I+ E++PFLVLAVG+DNIF+LV T +R +E +D +G L E+AP M +S+ ++T AF+ G LS MPAV TF+L+AG ++LI+FL QIT F+++L LD+KR + LD+ CC+ +G D + +Y + FF+ Y +P+L+K V V + + LS ++ + +GLD +MP SYV YF+ L Y GPPVYFV+ + ++ K QN +CG GCD S + + T + + SWIDDYF W V Q C L++
Sbjct: 315 SSDKGEASCCDPLGAAFDDCLRRMFTKWGAFCVRNPTCIIFFSLAFITVCSSGLVFVQVTTNPVELWSAPHSQARLEKEYFDKHFGPFFRTEQLIIQAPNTSVHIYEPYPA--GADVPFGPPLNKEILHQVLDLQIAIESITASYNNETVTLQDICVAPLSPYNKNCTIMSVLNYFQNSHAVLDSQVGDDFYIYADYHTHFLYCVRAPASLNDTSLLHGPCLGTFGGPVFPWLVLGGYDDQN----------YNNATALVITFPVNNYYNDTERLQRAWAWEKEFISFVK-NYKN-PNLTISFTAERSIEDELNRESNSDVFTVIISYVVMFLYISLALGHIQSCSRLLVDSKISLGIAGILIVLSSVACSLGIFSYMGMPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDE---RLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFGALSSMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNHLDILCCV--RGADDGQGSHASESY---LFRFFKNYFAPLLLKDWLRPIVVAVFVGV-LSFSVAVVNKVDIGLDQSLSMPNDSYVIDYFKSLAQYLHSGPPVYFVLEE-GYNYSSRKGQNMVCGGMGCDNDSLVQQIFNAAELDTYTRVGFAPSSWIDDYFDW------VSPQSSCCRLYN 961 HSP 2 Score: 131.724 bits (330), Expect = 7.356e-30 Identity = 75/213 (35.21%), Postives = 130/213 (61.03%), Query Frame = 0
Query: 759 FMAFHTVLRTSNDFVQAIESTRILSDKF-----ARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIM---GKR--SAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
FM +HT+L+TS D+ A++ R+++ ++ ++ FPYS+F+V+YEQYL++ DT+ +++ L ++ L+ + G ++ + ++ IL+++ G + + GI LNA+ VNL+++CGISVE C + M G R AEE + SGI +T G+ VL F++S IF ++F +Y+++V++G HGLI LPVLLS+
Sbjct: 1037 FMTYHTILKTSADYTDAMKKARLIASNITETMRSKGSDYRVFPYSVFYVFYEQYLTIIDDTIFNLSVSLGSIFLVTLVVLGCELWSAVIMCITIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTMSTKGSRVSRAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFEIFYFRMYLAMVLLGATHGLIFLPVLLSY 1249
BLAST of EMLSAG00000004370 vs. SwissProt
Match: gi|1100165154|sp|Q9VRC9.2|NPC1B_DROME (RecName: Full=Niemann-Pick type protein homolog 1B; Flags: Precursor) HSP 1 Score: 393.66 bits (1010), Expect = 5.996e-118 Identity = 243/744 (32.66%), Postives = 389/744 (52.28%), Query Frame = 0
Query: 25 NSKSCACLDXKQACPKLDADEYKEILTLKNEYMNFPIAYSVLIVILLLMLLVGIFLIAIKIKAKNRISSETQEESRKESIGWLLFQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDKITLQDVCYKPL-----APEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFVKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTIS---TFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW--SNDCCMVD-SQGKIC 753
+S +CAC+D +++CP DA T +E Y V ++ L++ F I K S E F FR G FC+K+ V VL LS G+ ++ +T++P+ELW+ S++R E D+F++HF PF+RT+ + + N+++ N + F F +V +LQ I K+ D L +CY P+ P + C +QSV+ Y+Q F + + + YL+ L C+ P M + C P+E +GG K D + +LA + L++TFL +N+ ++ ++E +KWEK FV ++ + LDIA++AE SIQDAI S G+V V+ISY +MFVYV+ AL R+ + F I LAI GI +VL S++ + G +G++ V TM+ E++PFLVLAVG+DNIF++V T +R S E IG + ++ P++L + ++ F +G +S MPAV TFA+YA ++L++FL QIT F+A++++D KR +LD+ CC+ G+ D + K + T F+ + SP L+ K VK SV+++ + ++L+ T +I GLD E +MPK S+V KYF ++ ++G PVY+V+ ++ + QN ICG C+ S + + P++T+LA SW+DDY W +DCC + + G C
Sbjct: 237 DSYACACIDCEESCPLTDAP------TGPDELWKIAGLYGVTFILALIIACALSFFIFWGAFGKTSAPSVCMPTLFGE-----FFYHGFRIWGTFCAKHPVIVLALCSWAIAGLSFGIRYMTITTDPVELWAGEESQTRIEKDYFDQHFGPFYRTNQMFVKAVNQTYFTHETSNGVL----NFGPAFEYNFLKEVFELQDSIMKLGMADNEGLDKICYAPVLMAGETPTVDRCAIQSVYGYFQHDMDRFENSYVDSNNYTINYLNQLEDCLRVP--------MMEDCFGTFGGPIEPGIAVGGMP--KVAVGEDPDYMLA--TGLVLTFLGRNYNDESKLEPNMKWEKLFVDFLRDYKSD--RLDIAYMAERSIQDAIVELSEGEVSTVVISYVVMFVYVAIALGHIRSCRGFLRESRIMLAIGGIVIVLASVVCSLGFWGYLDVTTTMLAIEVIPFLVLAVGVDNIFIMVHTYQRLDHSKFKTTHEA---IGEAIGQVGPSILQTAGSEMACFAIGCISDMPAVKTFAMYAAIAILLDFLLQITAFVALMAIDEKRYLDGRLDMLCCVKSGGKKINDEDGDGVDRPKEVGLLETLFKNFYSPFLLSK-PVKVSVLLIFTVITCLSLMVTPSIEKGLDQEMSMPKNSHVVKYFRYMVDLLAMGAPVYWVLKP-GLNYSEPLQQNLICGGVECNNNSLSVQLYTQAQYPEITSLARPASSWLDDYIDWLAISDCCKYNVTTGGFC 946 HSP 2 Score: 108.997 bits (271), Expect = 7.275e-23 Identity = 76/219 (34.70%), Postives = 118/219 (53.88%), Query Frame = 0
Query: 746 VDSQGKICILFSNFMAFHTVLRTSNDFVQAIESTRILSDKFA---RENNITS--FPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSGKIVIGLYTVTF-VSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIMGKRSAEE----VYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVL 954
+D G + S FM + T TS +F + R +S + +ENN+ + F Y +F++YYEQYL++ D + S+ L+ + L+ ++G + + V F V ILI++ G + I LNAI VNL+V GI VE + S + +A+E N ++SGI +T G+ VLGFS S IF ++F +Y+ IV+IG HGLI+L
Sbjct: 1006 IDDVGMSTVQDSYFMQYSTTSTTSEEFYSQLREVRRISGEINAMFKENNVDAEIFAYCVFYIYYEQYLTIWGDAMFSLGMSLVAIFLVTLLITGLDITSTFIVLFMVICILINMLGMMWAWSINLNAISLVNLVVCVGIGVEFVAHIVRSFKRAEGTAQERARHSLNVTGSSVLSGITLTKFAGIVVLGFSNSQIFQVFYFRMYLGIVLIGAAHGLILL 1224
BLAST of EMLSAG00000004370 vs. SwissProt
Match: gi|8134591|sp|P56941.1|NPC1_PIG (RecName: Full=Niemann-Pick C1 protein; Flags: Precursor) HSP 1 Score: 391.349 bits (1004), Expect = 6.059e-117 Identity = 226/657 (34.40%), Postives = 372/657 (56.62%), Query Frame = 0
Query: 110 QTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNL-YGKEATFSXIFRQEMFYQVLKLQKEIEKIIT---EDKITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHI-EKDRVEKAIKWEKSFVKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW---SNDCCMV-DSQGKIC 753
+ F + G FC ++ V+ + + SSG+ +++VT++P++LWS+ S++R+E ++F+ HF PFFR LII +N Q Y+ G + F +++ +QVL LQ IE I + +TLQD+C PL+P +C + SV NY+Q S+S + + + Y H CV P ++ ++ + CL P+ V+GG+ N +AL++TF + N+ + +++++A WE F+ +++ N +N P L I+F+AE SI+D + S+ D+ ++ISY +MF+Y+S AL ++ I+L IAGI +VL S+ + G+F +IGV T+I+ E++PFLVLAVG+DNIF+LV T +R L+G + D +G L E+AP+M +S+ ++T AF+LG LS +PAV TF+L+AG ++LI+FL QIT F+++L LD+KR + +LD+ CC+ +G D ++ + + FF+ +P+L+K + V + + LS ++ + +GLD +MP SYV YF+ L Y GPPVYFVV + + ++K QN +CG GC+ S + + + T + + SWIDDYF W + CC V +S + C
Sbjct: 336 RRLFAQWGAFCVRHPGCVVFFSLAFIVACSSGLVFIRVTTDPVDLWSAPGSQARREKEYFDTHFGPFFRMEQLIIRATNN---QSHIYHPYPAGADVPFGPPLSRDILHQVLDLQTAIENITASYNNETVTLQDICLAPLSPYNKNCTILSVLNYFQNSHSVLDHQVGDFFFVYADYHTHFLYCVRAPASLNDASLLHDPCLGTFGGPVFPWLVLGGYDDQN----------YNNATALVITFPVNNYYNDTEKLQRAQAWESEFINFVK-NYKN-PNLTISFMAERSIEDELNRESNSDLFTILISYAIMFLYISIALGHIKSCSRLLVDSKISLGIAGILIVLSSVACSLGIFSYIGVPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDE-RLQGETL--DQQLGRVLGEVAPSMFLSSFSETVAFFLGGLSVVPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNRLDVVCCV--QGAEDGAGVQAS---ESCLFRFFKNSYAPLLLKDWMRPIVIAVFVGV-LSFSIAVLNKVEIGLDQSLSMPDDSYVMDYFQSLSRYLHAGPPVYFVVEEGH-NYTSLKGQNMVCGGLGCNNDSLVQQIFTAAQLDNYTRIGFAPSSWIDDYFDWIKPQSSCCRVYNSTDQFC 967 HSP 2 Score: 134.806 bits (338), Expect = 8.178e-31 Identity = 79/214 (36.92%), Postives = 128/214 (59.81%), Query Frame = 0
Query: 759 FMAFHTVLRTSNDFVQAIESTRILSDKFARENNITS-----FPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIM----GKR--SAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
FM +HTVL+ S DF+ A++ R+++ R + + FPYS+F+V+YEQYL++ DT+ ++ L + L+ L G ++ + ++ IL+++ G + + GI LNA+ VNL+++CGISVE C ++T G R AEE + SGI +T G+ VL F++S IF ++F +Y++IV++G HGLI LPVLLS+
Sbjct: 1037 FMTYHTVLQASADFIDAMQKARLIASNITRTMGLEASSYRVFPYSVFYVFYEQYLTVIDDTIFNLGVSLGAIFLVTVVLMGCELWATVIMCVTIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFC-SHITRAFTLSTKGSRVDRAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAIVLLGATHGLIFLPVLLSY 1249
BLAST of EMLSAG00000004370 vs. SwissProt
Match: gi|83305902|sp|O15118.2|NPC1_HUMAN (RecName: Full=Niemann-Pick C1 protein; Flags: Precursor) HSP 1 Score: 390.963 bits (1003), Expect = 8.251e-117 Identity = 229/681 (33.63%), Postives = 378/681 (55.51%), Query Frame = 0
Query: 81 IAIKIKAKNRISSETQEESRKESIGWLLFQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXP--SNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIIT---EDKITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHI-EKDRVEKAIKWEKSFVKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW---SNDCCMVDS 748
IA + A ++ + + G L + F + G FC + V+ + + SSG+ +++VT+ P++LWS+ +S++R E ++F++HF PFFRT LII +++ Q + G + F ++ +QVL LQ IE I + +TLQD+C PL+P +C + SV NY+Q S+S + +D Y H CV P ++ ++ + CL P+ V+GG+ N +AL++TF + N+ + +++++A WEK F+ +++ N +N P L I+F AE SI+D + S DV V+ISY +MF+Y+S AL ++ + ++L IAGI +VL S+ + G+F +IG+ T+I+ E++PFLVLAVG+DNIF+LV +R L+G + D +G L E+AP+M +S+ ++T AF+LG LS MPAV TF+L+AG ++ I+FL QIT F+++L LD+KR + +LD+FCC+ +G D + ++ + + FF+ SP+L+K + + + + LS ++ + +GLD +MP SY+ YF+ + Y GPPVYFV+ + D + K QN +CG GC+ S + + + T + + SWIDDYF W + CC VD+
Sbjct: 309 IAFSVNASDKGEASCCDPVSAAFEGCL--RRLFTRWGSFCVRNPGCVIFFSLVFITACSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIRAPLTDKHIYQPYPS----GADVPFGPPLDIQILHQVLDLQIAIENITASYDNETVTLQDICLAPLSPYNTNCTILSVLNYFQNSHSVLDHKKGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDQN----------YNNATALVITFPVNNYYNDTEKLQRAQAWEKEFINFVK-NYKN-PNLTISFTAERSIEDELNRESDSDVFTVVISYAIMFLYISLALGHMKSCRRLLVDSKVSLGIAGILIVLSSVACSLGVFSYIGLPLTLIVIEVIPFLVLAVGVDNIFILVQAYQRDE-RLQGETL--DQQLGRVLGEVAPSMFLSSFSETVAFFLGALSVMPAVHTFSLFAGLAVFIDFLLQITCFVSLLGLDIKRQEKNRLDIFCCV--RGAEDGTSVQAS---ESCLFRFFKNSYSPLLLKDWMRPIVIAIFVGV-LSFSIAVLNKVDIGLDQSLSMPDDSYMVDYFKSISQYLHAGPPVYFVLEEGH-DYTSSKGQNMVCGGMGCNNDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQSSCCRVDN 961 HSP 2 Score: 135.191 bits (339), Expect = 6.951e-31 Identity = 78/213 (36.62%), Postives = 126/213 (59.15%), Query Frame = 0
Query: 759 FMAFHTVLRTSNDFVQAIESTRILSDKFARENNITS-----FPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEIC---IGYLTSVIMGKR--SAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
FM +HTVL+TS DF+ A++ R+++ I FPYS+F+V+YEQYL++ DT+ ++ L + L+ L G ++ + ++ +L+++ G + + GI LNA+ VNL+++CGISVE C T + G R AEE + SGI +T G+ VL F++S IF ++F +Y+++V++G HGLI LPVLLS+
Sbjct: 1038 FMTYHTVLQTSADFIDALKKARLIASNVTETMGINGSAYRVFPYSVFYVFYEQYLTIIDDTIFNLGVSLGAIFLVTMVLLGCELWSAVIMCATIAMVLVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRVERAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSY 1250
BLAST of EMLSAG00000004370 vs. SwissProt
Match: gi|73921247|sp|Q6T3U3.1|NPCL1_RAT (RecName: Full=Niemann-Pick C1-like protein 1; Flags: Precursor) HSP 1 Score: 385.571 bits (989), Expect = 1.422e-114 Identity = 247/756 (32.67%), Postives = 402/756 (53.17%), Query Frame = 0
Query: 25 NSKSCACLDXKQACPKLDADEYKEILTLKNE-YMNFPIAYSVLIVI------LLLMLLVGIFLIAIKIKAKNRISSETQEESRKESIG-WLLFQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKII-----TEDKITLQDVCYKPLAP---EIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDT---YLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFK-TDKSPESLDSEDILANTSALIMTFLLQNHIEKD-RVEKAIKWEKSFVKWIESNLENFP-LLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYFGI----TLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW---SNDCCMVDSQGK 751
+S C+C D +CP + E L+ YM + LI+I LL +LV + +++ + K K E + K + + FF+ G + + + VL + I+ I L++G+ ++++T++P+ELWS+ S++RKE F +EHF PFFRT+ + + N S +KY++L FS I + ++L+LQ+ + + E I+LQD+CY PL P + C + S+ Y+Q + + L Q + + DH C P T K T++ SC++ P+ +GG++ TD S ALI+TF L N+ D R+ +A WE++F+K +ES N +AF AE S++D I + D+ V +SY ++F+Y+S AL + + TL + G+ +VLG++L+ G + ++GV ++++I ++VPFLVLAVG DNIF+ VL +R L + G + E IG TL +AP+ML+ +L++ F+LG L+ MPAV TFAL +G +++++FL Q+T F+A+LSLD KR ++ + D+ CC S + + PK + + + FF K +P L+ + ++ VM+L L NI VGLD E +PK SY+ YF +L Y VGPPVYFV S + ++ N C SAGC +S ++ S PD + +A + SW+DD+ W S+ CC + +G
Sbjct: 250 DSAVCSCQDCAASCPVIPPPE-----ALRPSFYMGRMPGWLALIIIFTAVFVLLSAVLVRLRVVSNRNKNKAEGPQEAPKLPHKHKLSPHTILGRFFQNWGTRVASWPLTVLALSFIVVIALAAGLTFIELTTDPVELWSAPKSQARKEKSFHDEHFGPFFRTNQIFVTARNRS---SYKYDSLLLGSKNFSGILSLDFLLELLELQERLRHLQVWSPEAERNISLQDICYAPLNPYNTSLSDCCVNSLLQYFQNNRTLLMLTANQTLNGQTSLVDWKDHFLYCANAPLTFKDGTSLALSCMADYGAPVFPFLAVGGYQGTDYS-----------EAEALIITFSLNNYPADDPRMAQAKLWEEAFLKEMESFQRNTSDKFQVAFSAERSLEDEINRTTIQDLPVFAVSYIIVFLYISLALGSYSRCSRVAVESKATLGLGGVIVVLGAVLAAMGFYSYLGVPSSLVIIQVVPFLVLAVGADNIFIFVLEYQR-LPRMPGEQREAH--IGRTLGSVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAIILDFLLQMTAFVALLSLDSKRQEASRPDVLCCFSTR---KLPPPKEK---EGLLLRFFRKIYAPFLLHRF-IRPVVMLLFLTLFGANLYLMCNINVGLDQELALPKDSYLIDYFLFLNRYLEVGPPVYFVTTS-GFNFSSEAGMNATCSSAGCKSFSLTQKIQYASEFPDQSYVAIAASSWVDDFIDWLTPSSSCCRLYIRGP 975 HSP 2 Score: 100.138 bits (248), Expect = 4.736e-20 Identity = 85/325 (26.15%), Postives = 153/325 (47.08%), Query Frame = 0
Query: 659 SYVKKYFEWL-------KLYYSVGPPVYFVVNSTNMDLATVKS-QNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSWSNDCCMVDSQGKICILFSNFMAFHTVLRTSNDFVQAIESTRILSDKF--------ARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIMGKRSAEEVYNDQAGILM-----SGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSFF 961
S+V + +WL +LY GP ST+ +K+ NR G F + + P G + + S+D ++ SQ FMA+H LR S DF +A+ ++R+L+ + N FPY+I +V+Y+QYL++ + + ++A + ++C+ L G + G+ + + IL+ G +++ GI NA+ +NL+ A G+SVE S + + A + M +G+ +TN G+ +LGF+Q+ + +FF + + I ++G +HGL+ LPV+LS+
Sbjct: 952 SWVDDFIDWLTPSSSCCRLYIR-GPHKDEFCPSTDTSFNCLKNCMNRTLGPVRPTAEQFHKYLPWFLNDPPNIRCPKGGLAAYRTSVNLSSDGQVIASQ---------FMAYHKPLRNSQDFTEALRASRLLAANITADLRKVPGTDPNFEVFPYTISNVFYQQYLTVLPEGIFTLALCFVPTFVVCYLLLGLDMCSGILNLLSIIMILVDTIGLMAVWGISYNAVSLINLVTAVGMSVEFVSHITRSFAVSTKPTRLERAKDATVFMGSAVFAGVAMTNFPGILILGFAQAQLIQIFFFRLNLLITLLGLLHGLVFLPVVLSYL 1266
BLAST of EMLSAG00000004370 vs. SwissProt
Match: gi|425906049|sp|Q9UHC9.2|NPCL1_HUMAN (RecName: Full=Niemann-Pick C1-like protein 1; Flags: Precursor) HSP 1 Score: 364.385 bits (934), Expect = 1.002e-106 Identity = 226/743 (30.42%), Postives = 401/743 (53.97%), Query Frame = 0
Query: 28 SCACLDXKQACPKLDADEYKEILTLKNEYMNFPIAYSVLIVILLLMLLVGIFLIAIKIKAKNRISSETQEESRKESIG-------WLLFQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKII-----TEDKITLQDVCYKPLAPEIPS---CLLQSVWNYWQGSNSSFNLNITN---DRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKD-RVEKAIKWEKSFVKWIESNLENFP-LLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYFGI----TLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW--SNDCC 744
+C+C D +CP + + L P + ++I++ + +V I L+ ++ A R S+ + + S+ L FF+ G + + + + +L+ + I + L++G+ + ++T++P+ELWS+ NS++R E F ++HF PFFRT+ +I+ N S ++Y++L FS I ++ ++L+LQ+ + + + I+LQD+CY PL P+ S C + S+ Y+Q + + L + Q + DH C P T K TA+ SC++ P+ +GG+K E+ ALIMTF L N+ D R+ +A WE++F++ + + + + F+AE S++D I + D+ + SY ++F+Y+S AL + + + TL + G+ +VLG++++ G F ++G++++++I ++VPFLVL+VG DNIF+ VL +R L G EV IG L +AP+ML+ +L++ F+LG L+ MPAV TFAL +G +++++FL Q++ F+A+LSLD KR ++ +LD+ CC+ + ++ P + + FF+K +P L+ +T + V++L ++L +I VGLD E +PK SY+ YF +L Y+ VG PVYFV + + ++ N IC SAGC+ +SF ++ + P+ + LA SW+DD+ W + CC
Sbjct: 253 TCSCQDCAASCPAI---ARPQALDSTFYLGQMPGSLVLIIILCSVFAVVTILLVGFRV-APARDKSKMVDPKKGTSLSDKLSFSTHTLLGQFFQGWGTWVASWPLTILVLSVIPVVALAAGLVFTELTTDPVELWSAPNSQARSEKAFHDQHFGPFFRTNQVILTAPNRS---SYRYDSLLLGPKNFSGILDLDLLLELLELQERLRHLQVWSPEAQRNISLQDICYAPLNPDNTSLYDCCINSLLQYFQNNRTLLLLTANQTLMGQTSQVDWKDHFLYCANAPLTFKDGTALALSCMADYGAPVFPFLAIGGYKGKDYSEA----------EALIMTFSLNNYPAGDPRLAQAKLWEEAFLEEMRAFQRRMAGMFQVTFMAERSLEDEINRTTAEDLPIFATSYIVIFLYISLALGSYSSWSRVMVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLVILQVVPFLVLSVGADNIFIFVLEYQR-LPRRPGEPREVH--IGRALGRVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAVILDFLLQMSAFVALLSLDSKRQEASRLDVCCCVKPQ---ELPPPGQG---EGLLLGFFQKAYAPFLLHWIT-RGVVLLLFLALFGVSLYSMCHISVGLDQELALPKDSYLLDYFLFLNRYFEVGAPVYFVT-TLGYNFSSEAGMNAICSSAGCNNFSFTQKIQYATEFPEQSYLAIPASSWVDDFIDWLTPSSCC 967 HSP 2 Score: 80.4925 bits (197), Expect = 5.463e-14 Identity = 66/218 (30.28%), Postives = 115/218 (52.75%), Query Frame = 0
Query: 757 SNFMAFHTVLRTSNDFVQAIES--------TRILSDKFARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLL-TMLLICWFLSGKIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIMGKRS-----AEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
S FMA+H L+ S D+ +A+ + T L + FPY+I +V+YEQYL++ + L ++ L+ T + C L + GL + + IL+ GF+++ GI NA+ +NL+ A G+SVE S + + A+E + +G+ +TNL G+ VLG +++ + +FF + + I ++G +HGL+ LPV+LS+
Sbjct: 1074 SRFMAYHKPLKNSQDYTEALRAARELAANITADLRKVPGTDPAFEVFPYTITNVFYEQYLTILPEGLFMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWGISYNAVSLINLVSAVGMSVEFVSHITRSFAISTKPTWLERAKEATISMGSAVFAGVAMTNLPGILVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSY 1291
BLAST of EMLSAG00000004370 vs. SwissProt
Match: gi|73921246|sp|Q6T3U4.1|NPCL1_MOUSE (RecName: Full=Niemann-Pick C1-like protein 1; Flags: Precursor) HSP 1 Score: 348.977 bits (894), Expect = 2.046e-101 Identity = 243/756 (32.14%), Postives = 402/756 (53.17%), Query Frame = 0
Query: 25 NSKSCACLDXKQACPKLDADEYKEILTLKNE-YMNFPIAYSVLIVILLLMLLVGIFLIAIKIKAKNRISSET---QEES---RKESIG-WLLFQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQK-----EIEKIITEDKITLQDVCYKPLAPE---IPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDT---YLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFK-TDKSPESLDSEDILANTSALIMTFLLQNHIEKD-RVEKAIKWEKSFVKWIES-NLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYFGI----TLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW---SNDCCMVDSQGK 751
+S +C+C D +CP + L+ YM + LI+I + ++ ++ A NR ++T QE RK + FF G + + + VL + I+ I LS G+ ++++T++P+ELWS+ S++RKE F +EHF PFFRT+ + + N S +KY++L FS I ++ ++L+LQ+ ++ + I+LQD+CY PL P + C + S+ Y+Q +++ L Q + + DH C P T K TA+ SC++ P+ +GG++ TD S ALI+TF + N+ D R+ A WE++F+K ++S IAF AE S++D I + D+ V ISY ++F+Y+S AL + + TL + G+ +VLG++++ G + ++GV ++++I ++VPFLVLAVG DNIF+ VL +R L + G + E IG TL +AP+ML+ +L++ F+LG L+ MPAV TFAL +G +++ +FL Q+T F+A+LSLD KR ++ + D+ CC S + ++ PK + + + FF K +P L+ + ++ V++L + L NI VGLD + +PK SY+ YF +L Y VGPPVYF S + +T N IC SAGC+ +S ++ S P+ + +A + SW+DD+ W S+ CC + ++G
Sbjct: 250 DSAACSCQDCAASCPVIPPPP-----ALRPSFYMGRMPGWLALIIIFTAVFVLLSVVLVYLRVASNRNKNKTAGSQEAPNLPRKRRFSPHTVLGRFFESWGTRVASWPLTVLALSFIVVIALSVGLTFIELTTDPVELWSAPKSQARKEKAFHDEHFGPFFRTNQIFVTAKNRS---SYKYDSLLLGPKNFSGILSLDLLQELLELQERLRHLQVWSHEAQRNISLQDICYAPLNPHNTSLTDCCVNSLLQYFQNNHTLLLLTANQTLNGQTSLVDWKDHFLYCANAPLTYKDGTALALSCIADYGAPVFPFLAVGGYQGTDYS-----------EAEALIITFSINNYPADDPRMAHAKLWEEAFLKEMQSFQRSTADKFQIAFSAERSLEDEINRTTIQDLPVFAISYLIVFLYISLALGSYSRWSRVAVDSKATLGLGGVAVVLGAVVAAMGFYSYLGVPSSLVIIQVVPFLVLAVGADNIFIFVLEYQR-LPRMPGEQREAH--IGRTLGSVAPSMLLCSLSEAICFFLGALTSMPAVRTFALTSGLAIIFDFLLQMTAFVALLSLDSKRQEASRPDVVCCFSSR---NLPPPKQK---EGLLLCFFRKIYTPFLLHRF-IRPVVLLLFLVLFGANLYLMCNISVGLDQDLALPKDSYLIDYFLFLNRYLEVGPPVYFDTTS-GYNFSTEAGMNAICSSAGCESFSLTQKIQYASEFPNQSYVAIAASSWVDDFIDWLTPSSSCCRIYTRGP 975 HSP 2 Score: 102.064 bits (253), Expect = 1.095e-20 Identity = 69/221 (31.22%), Postives = 121/221 (54.75%), Query Frame = 0
Query: 754 ILFSNFMAFHTVLRTSNDFVQAIESTRILSDKFARE--------NNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIMGKRSAEEVYNDQAGILM-----SGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
I+ S FMA+H LR S DF +A+ ++R+L+ E N FPY+I +V+Y+QYL++ + + ++A + ++C+ L G I G+ + + IL+ G +++ GI NA+ +NL+ A G+SVE S + + A I M +G+ +TN G+ +LGF+Q+ + +FF + + I ++G +HGL+ LPV+LS+
Sbjct: 1045 IIASQFMAYHKPLRNSQDFTEALRASRLLAANITAELRKVPGTDPNFEVFPYTISNVFYQQYLTVLPEGIFTLALCFVPTFVVCYLLLGLDIRSGILNLLSIIMILVDTIGLMAVWGISYNAVSLINLVTAVGMSVEFVSHITRSFAVSTKPTRLERAKDATIFMGSAVFAGVAMTNFPGILILGFAQAQLIQIFFFRLNLLITLLGLLHGLVFLPVVLSY 1265
BLAST of EMLSAG00000004370 vs. SwissProt
Match: gi|74676548|sp|Q12200.1|NPC1_YEAST (RecName: Full=Niemann-Pick type C-related protein 1; Flags: Precursor) HSP 1 Score: 236.884 bits (603), Expect = 2.799e-63 Identity = 244/1013 (24.09%), Postives = 432/1013 (42.65%), Query Frame = 0
Query: 29 CACLDXKQACPKLDADEYKEILTLKNEYMNFPIAYSVLIVILLLMLLVGIFLIAIKIKAKNRISSETQEESRK-ESIGWLLFQTF--------------FRKLGYFCSKYAVYVLICNGIIFIVLSSGVF-WLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITE-----DKITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFVKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYFGITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGS-AGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSWSN----DCCMVD--------------------SQGKICILFSNFMAFHTVLRTSNDFVQAIESTRILSDKFAREN----NITSFPYSIFHVYYEQYLSMKT---------------DTLVSIAYVLLTMLLICWFLSGKIVIGLYT-----VTFVSSILIH-------VTGFISMLGIQLNAILA-----------VNLLVACGISVEICIGYLTSVIMGKRSAEEVYNDQ--------AGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVI 945
CAC D +++CP L K+ + F ++ + I L + +L K + + ES + +F++F F K+G F + +LI V S +F + + ++PI LW S NS KE ++F+++F PF+RT + + L Y+ L ++E ITE + I QD+C++P E +C+++S Y+QG+ ++D++ L C + P +CL PL+ + S+D + N A ++T LL NH + A +WE+ +++ +L+ L I+F E+S++ E N++ D+ V ISY +MF+Y ++AL R + L I+G+ +VL SI+ G G+K+T+II E++PFL+LA+GIDNIF++ R + E +D I + ++P++L+S L QT F + MPAV FA+Y+ S++ N + Q+T +++ILSL KR K++ N +++ ++ KT K LT K ++++ + +LVF I GLD +P+ SY+ YF+ + + +VGPPVY VV N+DL ++Q +ICG C+ S ++ + +T+ +W+DDYF + N CC + QG S F + + ++ A L + N TS S+F + S K L AY + + + G + + L + F+SS+ + + ++M+ + + A++A VNL++ G+ VE C+ + S + ++ N + ++ GI +T IGV VL F+QS IF ++F ++ +++++
Sbjct: 230 CACSDCQESCPHLKP--LKDGVCKVGPLPCFSLSVLIFYTICALFAFMWYYLCKRKKNGAMIVDDDIVPESGSLDESETNVFESFNNETNFFNGKLANLFTKVGQFSVENPYKILITTVFSIFVFSFIIFQYATLETDPINLWVSKNSEKFKEKEYFDDNFGPFYRTEQIFVVNETGPVLS-----------------------YETLHWWFDVENFITEELQSSENIGYQDLCFRPT--EDSTCVIESFTQYFQGA-----------LPNKDSWKRELQECGKFPV----------NCLPTFQQPLKTNLLF-------------SDDDILNAHAFVVTLLLTNH-----TQSANRWEERLEEYL-LDLKVPEGLRISFNTEISLEK--ELNNNNDISTVAISYLMMFLYATWALR--RKDGKTRLLLGISGLLIVLASIVCAAGFLTLFGLKSTLIIAEVIPFLILAIGIDNIFLITHEYDRN--CEQKPEYSIDQKIISAIGRMSPSILMSLLCQTGCFLIAAFVTMPAVHNFAIYSTVSVIFNGVLQLTAYVSILSLYEKRSNYKQI-------------TGNEETKESFLKTF-----------YFKMLTQKRLIIIIFSAWFFTSLVFLPEIQFGLDQTLAVPQDSYLVDYFKDVYSFLNVGPPVYMVVK--NLDLTKRQNQQKICGKFTTCERDSLANVLEQERHR---STITEPLANWLDDYFMFLNPQNDQCCRLKKGTDEVCPPSFPSRRCETCFQQGSWNYNMSGFPEGKDFMEYLSIWINAPSDPCPLGGRAPYSTALVYNETSVSASVFRTAHHPLRSQKDFIQAYSDGVRISSSFPELDMFAYSPFYIFFVQYQTLGPLTLKLIGSAIILIFFISSVFLQNIRSSFLLALVVTMIIVDIGALMALLGISLNAVSLVNLIICVGLGVEFCVHIVRSFTVVPSETKKDANSRVLYSLNTIGESVIKGITLTKFIGVCVLAFAQSKIFDVFYFRMWFTLIIV 1140
BLAST of EMLSAG00000004370 vs. SwissProt
Match: gi|37999494|sp|Q19127.2|NPC1_CAEEL (RecName: Full=Niemann-Pick C1 protein homolog 1; Flags: Precursor) HSP 1 Score: 230.72 bits (587), Expect = 4.366e-61 Identity = 179/716 (25.00%), Postives = 325/716 (45.39%), Query Frame = 0
Query: 70 LLLMLLVGIFLIAIKIKAKNRISSETQEESRKESI-----GWL--LFQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHF-EPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDK----ITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDR---------------GHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFVKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDF---RNK-----KYFGITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLE-GREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW---SNDCCMV 746
L ++L VG + N +++ EES K + W+ + R +G + + I G+ + K ++ +++WSS SR+R+E FN +F P I+++ S+ F K LYG +F +++F ++ + I+ I T+D ITL DVCY+P+ P CL+ S NY+QG+ ++ + D +++H+ C++ P + K T G SC+ P V G T+ ++++MT L+ E + ++KA WEK F+K+ + E P + +F+AE SI D IE+++ +++ V+I+ + YV+F+L + N+ + I L + + + L S + G+F G+ + F+V +G+ F++V ++ +S+ + ++G+ + PAM S+L +F++G + +PA+ TF LYAG ++LI+ + T F+A+ D +R + K + F K + + ++ FF V+P LM ++T + ++ IA + T++ + I VG D + SY+ +F +L ++ VGPPV+F V+ +D QN+ C GC SF M + T L+ +WID+Y W + CC V
Sbjct: 292 LAVLLCVGFVFTSYDEDYTNLRQTQSGEESPKRNRIKRTGAWIHNFMENNARDIGMMAGRNPKSHFFIGCAVLIFCLPGMIYHKESTNVVDMWSSPRSRARQEEMVFNANFGRPQRYQQIMLL--SHRDFQSSGK---LYGP------VFHKDIFEELFDILNAIKNISTQDSDGRTITLDDVCYRPMGPGY-DCLIMSPTNYFQGNKEHLDMKSNKEETVSEDDDAFDYFSSEATTDEWMNHMAACIDQPMSQK--TKSGLSCMGTYGGPSAPNMVFGKNSTNHQA-----------ANSIMMTILVTQRTEPE-IQKAELWEKEFLKFCKEYREKSPKVIFSFMAERSITDEIENDAKDEIVTVVIALAFLIGYVTFSLGRYFVCENQLWSILVHSRICLGMLSVIINLLSSFCSWGIFSMFGIHPVKNALVVQFFVVTLLGVCRTFMVVKYYAQQRVSMPYMSPDQCPEIVGMVMAGTMPAMFSSSLGCAFSFFIGGFTDLPAIRTFCLYAGLAVLIDVVLHCTIFLALFVWDTQRELNGKPEFFFPYQIKDLLGAYLIGRQRATDTFMTQFFHFQVAPFLMHRMTRIITGIIFIA-SFITTVILSSKISVGFDQSMAFTEKSYISTHFRYLDKFFDVGPPVFFTVDG-ELDWHRPDVQNKFCTFPGCSDTSFGNIMNYAVGHTEQTYLSGEMYNWIDNYLEWISRKSPCCKV 979 HSP 2 Score: 82.4185 bits (202), Expect = 1.122e-14 Identity = 70/223 (31.39%), Postives = 108/223 (48.43%), Query Frame = 0
Query: 748 SQGKICILFSNFMAFHTVLRTSN--DFVQAIESTRILSDKFARENNITS--FPYSIFHVYYEQYLS-MKTDTLVSIAYVLLTMLLICWFLSGKIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGI----SVEICIGYLTSVIM-GKRSAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
S+G+I S FM FH L SN DF++A+++ R++S + R + T+ F YS +YEQY + M T V+ +IC L + V S H+ F+ + I +NA+ A NL+++ GI SV + GY S+ K AE I++SG +T L + I YFF +++ +V VH LI+LP+LL+F
Sbjct: 1062 SRGRI--QASQFMTFHKKLSISNSSDFIKAMDTARMVSRRLERSIDDTAHVFAYSKIFPFYEQYSTIMPILTTQLFITVVGVFGIICVTLGIDVKGAACAVICQVSNYFHIVAFMYIFNIPVNALSATNLVMSSGILIEFSVNVLKGYACSLRQRAKDRAESTVGSIGPIILSGPVVTMAGSTMFLSGAHLQIITVYFFKLFLITIVSSAVHALIILPILLAF 1282
BLAST of EMLSAG00000004370 vs. SwissProt
Match: gi|37999933|sp|P34389.2|NPC2_CAEEL (RecName: Full=Niemann-Pick C1 protein homolog 2; Flags: Precursor) HSP 1 Score: 153.68 bits (387), Expect = 1.352e-36 Identity = 177/767 (23.08%), Postives = 331/767 (43.16%), Query Frame = 0
Query: 28 SCACLDXKQACPKLDADEYKEILTLKNEYMNFPIAYSVLIVILLLMLLVGIFLIAIKIKAKNRISSETQEESRKESIGWLLFQTFFRKLGYFCSKYAVYVLICNGIIFIVLS--------SGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIX--PSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDKITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSF---NLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFVKWI---ESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYV-----------SFALTDFRNKKYFGITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRK-----LLSLEGREMEVDSLIGITLEEIAPAMLISTL-TQTCAFYLGTL-----SKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCC--LSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQS--WIDDYFSW---SNDCCMVDSQ 749
+C +D +L E L K + +FP +L + L L V L+ I + +R S+ E+ +G + F L C++YA V I + +IF+ L SG F + ++ S+ + +R+ F F P R + I P+ +S F+ +EMF V +Q + + L D+CYKP+ C + S NY+Q ++F +D D + +HL C+ NP T+ + + M SC + P++ V GG S ES+ ++ +++T L+ + ++AI WE +F+ + E NF F+ E S+ + I + D +V +I+ + ++V S L+ + K + ++I+ + + + S+ + G+F GV AT ++ F++ +GI+ IFV++ T + L ++ REM + I + P +L ++L TC F G + MPAV FA +AG ++L++ + + + D +R S K +++ LS++ +I++ N + + +F+ ++P+L+KK+ + + ++L I TL + G + + SY+ K+F+ + ++GPP++FVV ++ K QN+ C AGCD S ++ + + G W+D Y + CC +D +
Sbjct: 234 ACGAIDCPTNAHQLVDISKVEHLGTKVFHPHFPDFEWLLKICGCLALTV--LLVFILKYSCHRRSAPNGEDGCYVDLGKGNLEVQFEGL---CARYANAV-IKHPLIFVSLGLIVAAACCSGNFKFHSLTHSVDQVSAADGETRRNEKKFIHSFGPNHRIEQIFINLPPTTKSM---------------FNMPLFEEMFQLVGNIQN-LTACYGNSSVKLDDICYKPIGKN-HGCAIMSPTNYFQNKWTNFENAGPPTIDDEIFDDQHWEHLKYCIRNPLTVSTYSEM--SCFGEFSGPIDPILVFGG-----SNESIKGAEMYYTARTIMITVLI-----RGPEDQAIAWETAFLNMMSRYEMKHANF-----TFMTETSVAEEIHTAVETDKIVSVIACAAVLIWVITMLGINHWPESSILSALVHHK---LLISISAVMISVISVWCSIGMFSLFGVHATDNAIVVLFFVITCLGINRIFVIIRTFQANGHCYGLPNISYREM--NHRISNVMRRSIPIVLTNSLICSTCLFLAGGVLPYVSVSMPAVEVFARHAGLAILMDTAFYLLVMLPLFQYDARREMSGKCEIWPWYELSNESKINLCMEAVDGNLRSPVD-WFKLAIAPLLLKKI-CRIWIATFFFVSLIIACYCTLCLEFGFNQVMAFSETSYLTKHFQNMNENLNIGPPLWFVVEG-DVKWHDPKMQNKFCTLAGCDDNSMGNKIRSLAYAENYKGNYLHGDVNIWLDSYLQFMHPRGSCCKMDGK 952 HSP 2 Score: 64.3142 bits (155), Expect = 4.444e-9 Identity = 57/204 (27.94%), Postives = 93/204 (45.59%), Query Frame = 0
Query: 770 NDFVQAIESTRI---LSDKFARENNITS---FPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLL-ICWFLSGKIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIMGKRSAEEVYN-----DQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSFF 961
+D +Q ++ R L+D RE I + YS F YYEQYL++ T + VL + I FL + L TV + S +H+ ++ +LGI +N + +N+ ++ GI+VE L K+ E +SGI +I L F+ S + YF + I ++ VHG++ +P LL+ F
Sbjct: 1032 SDSIQLYDAWRFAKYLADDIERELEIPGVKVYVYSTFFPYYEQYLTLSTTVYTLVVLVLFVAFVTISLFLRVNLAGSLVTVFVLLSSYLHLMEWMYLLGITVNVVSVINMAMSLGIAVEFFGQMLHGFYNSKKPKREERAFAALVSNGSTTLSGIFPAIMITAGCLSFADSRVLITYFCNQLVGIGLVCAVHGVVYMPTLLAIF 1235
BLAST of EMLSAG00000004370 vs. Select Arthropod Genomes
Match: gb|EEC13272.1| (Niemann-Pick type C1 domain-containing protein, putative [Ixodes scapularis]) HSP 1 Score: 493.041 bits (1268), Expect = 1.887e-152 Identity = 340/1062 (32.02%), Postives = 554/1062 (52.17%), Query Frame = 0
Query: 5 NFSFVSLIPEYLFCQLIIILNSKSCACLDXKQACPKL------DADEYKEILTLKNEYMNFPIAYSVLIVILLLMLLVGIFLIAIKIKAK-NRISSETQEESRKESIGWLLFQTF----FRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSN-ESF---LQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITED---KITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFVKWIESNLENF--PLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLT-ARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKL-----------------------WSTKPDLTTL-ATSGQ----------------------------------SWIDD----------YFSWSNDCCMVDSQGKICILFSNFMAFHTVLRTSNDFVQAIESTRILSDKF-------ARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSGKIVIGLYTVTF-VSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIMGKRS-----AEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
N ++V + + C ++C+C AC K+ D + I + Y+ I +S+ +VI+L + + G L K +A N + ++ E G + QT F + G FC+++ + VL + + ++ SG+ +L + ++P++LWS+ SR+R E + FN+ F PF+R +I+ ++ E F ++K +N + TF +F + F++V LQ+ + ++ E +TL+D+C P+ + CL+ S NY+Q + S +L D+G TYL+HL C+ P +++ T SCL P+ +GG E AN+SAL++T ++ N+I+ V AI WE+ F++ L+NF P + ++F++E+SI+D ++ S DVL V+ISYF+MFVYVS AL +R+ +TL ++G+ +VL S+ S+ GLF F G T+I+ E++PFLVLAVG+DNIF+LV R +L E + +V ++G + P+++++++++ F LG LS MPAV TFALYAG +LL++FL Q+T F+A+L+LD KR ++++LD+ CC+S E+ + P + F Y FEKY +P LM+ V+ VM++ I+L T I +GLD E MP SY++ YF K +VGPP+YFVV + K Q+ +CGSAGC P S + ++L WS D + AT+ Q ++DD + ++SN + +S G I + FMA+H L S DF I+ +R ++D + +N T FPYSIFHV+YEQYL++ + L+ + + + +I + L + V + IL+ + G + GI LNA+ VNL++A GISVE C + + ++ RS +++ ++SGI +T GV VL FS S +F ++F +Y+SIV+IG HGL+ LPVLLS+
Sbjct: 163 NKTYVPMNDTFRKCSEPGAPGKEACSCSSCLDACSKIVPVYPQDPKPWT-IFRVDGFYIVAGIVFSIFLVIVLAVAVSGYVLRRFKDEANLNLLKAD------DEMGGGGILQTALVVGFGRWGGFCARHPLPVLAASAAVVVICCSGLAFLTILTDPVKLWSAPGSRARVERNLFNKEFGPFYRIEQVIVTRNDGEPFNYLVKKIGFN----RTVTFGSVFEKHFFHEVAALQESLLQLTAEHDGRNVTLKDICNSPM--DNGECLIMSPLNYFQNNASLLDLE---DQGR--TYLEHLDFCLSGPLSVEDKTFANLSCLGAYGGPVFPFVALGGVY----------EGNYANSSALVITLMVNNNIDPSLVAPAIAWERLFIE----TLKNFSHPNMSVSFLSEISIEDELQRESQSDVLTVLISYFIMFVYVSLALGQYRSWSTLMMDSQVTLGLSGVVIVLASVASSLGLFSFAGSPVTLIVIEVIPFLVLAVGVDNIFILVQGFQRANVLDEEPLDQKVSRVVG----NLGPSLMLASVSEAACFLLGGLSTMPAVRTFALYAGVALLLDFLLQVTCFVALLTLDAKRQRARRLDMCCCISRTPELLEEPPSNGFLY-----GLFEKYYAPNLMRA-PVRLVVMLVFVGWACISLAVTNKIEIGLDQEIAMPLDSYLQGYFHMQKTALAVGPPLYFVVQ-PGYNYTGKKDQDLVCGSAGCAPDSLVSQIQLASIYSNVTTISQPAQSWLDDYISWSGTQDCCRMNATTKQFCPRHENTTGCVSCLSDQKTMSRPLGETFSRFLPDFLDDVPDPKCPKGGHAAYSNAVQLYNSNGST-IGATQFMAYHAPLANSGDFTHGIKMSRFIADNVTATLRASSTAHNATVFPYSIFHVFYEQYLTIVNEALLHLGISVAGIFVITFLLLDLDLHAAAVVCLTILMILVDLLGIMYFWGIALNAVSLVNLVMAVGISVEFCSHIVRAFLVSSRSTRLLRSQDSLARMGSSVLSGITLTKFGGVVVLAFSTSQLFRIFYFRMYLSIVLIGAAHGLVFLPVLLSY 1180
BLAST of EMLSAG00000004370 vs. Select Arthropod Genomes
Match: gb|KYB26045.1| (Niemann-Pick C1 protein-like Protein [Tribolium castaneum]) HSP 1 Score: 473.011 bits (1216), Expect = 2.827e-147 Identity = 336/1071 (31.37%), Postives = 538/1071 (50.23%), Query Frame = 0
Query: 8 FVSLIPEYLFCQLIIILNSKSCACLDXKQACPKLDADEYK----EILTLKNEYMNFPIAYSVLIVILLLMLLVGIFLIAIKIKAK----------NRISSETQEESR-KESIGW---LLFQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDKITLQDVCYKPL------APEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFVKWIE--SNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGRE-MEVDSL-IGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCL--SDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW---SNDCCMVD-SQGKICILFSNFMAFHTV-------LRTSNDFVQAI---------------------ESTRILSDKFARENNITSFPYSIFHV-------YYEQYLSMK------TDTL-------------VSIAYVLLTMLLICW---FLSGKIVI-GLYTVTFV---------SSILIHVTGFISMLG-------IQLNAILAVNLLVACGISVEICIGYLTSVIMG------KRSAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
+ L PE C S +C+C+D +++CP I + I + V ++ LL++ V I + ++ N++ E + S E +G Q FF G C++ VL + + L G+ +LKVT++P+ELW+S SRSR E ++F+ HFEPF+R +II N L + +N G E F F +VLKLQ+ I+ I + L +C+ PL + ++ C++QS+W Y+Q +F+ + G + YLD+ +C +NP+ K CL+ P++ MGGF + E+L + N +A+I+TFL+ N+ K ++ A++WEK+FV +++ + E ++IAF +E SI+D ++ S DV+ +++SY +MF Y++ +L ITL + G+ +VL S++S+ GLFGF+G+ AT+II E++PFLVLAVG+DNIF+LV T +R EG++ E + IG TL ++ P+ML+++++++C F+LG+LS MPAV FALYAG +LL +FL QIT F+++LSLD R S + D+ CC K EI + N + + +FF+ P+LM + F VM++ L ++ +I +GLD E +MP+ SYV KYF++LK S+GPP+YFVV ++ + K+QN ICG CD S T + S P+ T +A SW+DDY W + CC + + G C A + T NDF + + ++K + + + + +H YYE S + T+T+ S+ YV L W S I + ++ VTF+ + ++I +T + LG I LNA+ VNL++A GI+VE C + S + +R+A+ + + I SGI +T G+ VLGF++S IF ++F +Y+ IV+ G HGLI LPVLLS+
Sbjct: 241 YQPLNPEITPCNKAFDSKSAACSCVDCEESCPVPPPQPPAPQPFTIAGFDGYFFLMIIVFCVGTLMFLLVVFVCPSRAEIGVTSEMGHELDTHSINKMPGEYESSSSFLEKLGANTDTFLQRFFEWWGTICAERPWLVLFLGACVVVGLGHGIKYLKVTTDPVELWASPTSRSRIEKEYFDSHFEPFYRNEQVIIKAVN---LPQIHHNTSNG-EVVFGPAFDATFLKEVLKLQERIKAIGADTDYALGRICFAPLRSVGKVSTDVEECVVQSIWGYYQNDEETFDETDVDPDGFETNYLDYFISCAQNPYNPK--------CLAPYGGPVDPAIAMGGFL--QPGENLSKQPNYQNATAVILTFLVNNYHNKTKLSPAMEWEKAFVAFMKNYTTSEKPSYMEIAFTSERSIEDELDRESQSDVVTILVSYIIMFAYIAVSLGQVNTCSRLLIDSKITLGLGGVLIVLASVVSSVGLFGFVGLPATLIIIEVIPFLVLAVGVDNIFILVQTHQR-----EGKKPTETHAQHIGRTLGQVGPSMLLTSVSESCCFFLGSLSDMPAVKAFALYAGMALLFDFLLQITCFVSLLSLDTIRQASNRFDI-CCFIKGSKKEI------VQTNQEGLLYSFFKSIYVPLLMNRFVRAF-VMIVFFGWLCSSIAVVPHIEIGLDQELSMPEDSYVLKYFKFLKDDLSIGPPMYFVVKD-GLNYSDPKAQNVICGGQYCDLDSLITQVFEASKVPERTYIARPSSSWLDDYIDWAAAAKTCCKYNKTTGAFCPHTKGTCATCNISYLPLNHRPTPNDFEHYVSFFLQDNPDETCAKAGHAAYSQGVNYATNKTTHLSKVGASYFMAYHTILKTSKDYYESMRSARKVSANITNTINTKIPSSQIEVFPYSVFYVFYEQYLTMWPDTLQSMAISLAAIFVVTFLLMGLDFFSSAVVVITITMIVVNLGGLMYWWHITLNAVSLVNLVMAVGIAVEFCSHLVHSFSVSLKTTRVERAADSLTRMGSSIF-SGITLTKFGGIIVLGFAKSQIFQVFYFRMYLGIVLFGAAHGLIFLPVLLSY 1282
BLAST of EMLSAG00000004370 vs. Select Arthropod Genomes
Match: gb|EFA11848.2| (Niemann-Pick C1 protein-like Protein [Tribolium castaneum]) HSP 1 Score: 468.774 bits (1205), Expect = 2.679e-145 Identity = 314/951 (33.02%), Postives = 496/951 (52.16%), Query Frame = 0
Query: 110 QTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDKITLQDVCYKPL------APEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFVKWIE--SNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGRE-MEVDSL-IGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCL--SDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW---SNDCCMVD-SQGKICILFSNFMAFHTV-------LRTSNDFVQAI---------------------ESTRILSDKFARENNITSFPYSIFHV-------YYEQYLSMK------TDTL-------------VSIAYVLLTMLLICW---FLSGKIVI-GLYTVTFV---------SSILIHVTGFISMLG-------IQLNAILAVNLLVACGISVEICIGYLTSVIMG------KRSAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
Q FF G C++ VL + + L G+ +LKVT++P+ELW+S SRSR E ++F+ HFEPF+R +II N L + +N G E F F +VLKLQ+ I+ I + L +C+ PL + ++ C++QS+W Y+Q +F+ + G + YLD+ +C +NP+ K CL+ P++ MGGF + E+L + N +A+I+TFL+ N+ K ++ A++WEK+FV +++ + E ++IAF +E SI+D ++ S DV+ +++SY +MF Y++ +L ITL + G+ +VL S++S+ GLFGF+G+ AT+II E++PFLVLAVG+DNIF+LV T +R EG++ E + IG TL ++ P+ML+++++++C F+LG+LS MPAV FALYAG +LL +FL QIT F+++LSLD R S + D+ CC K EI + N + + +FF+ P+LM + F VM++ L ++ +I +GLD E +MP+ SYV KYF++LK S+GPP+YFVV ++ + K+QN ICG CD S T + S P+ T +A SW+DDY W + CC + + G C A + T NDF + + ++K + + + + +H YYE S + T+T+ S+ YV L W S I + ++ VTF+ + ++I +T + LG I LNA+ VNL++A GI+VE C + S + +R+A+ + + I SGI +T G+ VLGF++S IF ++F +Y+ IV+ G HGLI LPVLLS+
Sbjct: 407 QRFFEWWGTICAERPWLVLFLGACVVVGLGHGIKYLKVTTDPVELWASPTSRSRIEKEYFDSHFEPFYRNEQVIIKAVN---LPQIHHNTSNG-EVVFGPAFDATFLKEVLKLQERIKAIGADTDYALGRICFAPLRSVGKVSTDVEECVVQSIWGYYQNDEETFDETDVDPDGFETNYLDYFISCAQNPYNPK--------CLAPYGGPVDPAIAMGGFL--QPGENLSKQPNYQNATAVILTFLVNNYHNKTKLSPAMEWEKAFVAFMKNYTTSEKPSYMEIAFTSERSIEDELDRESQSDVVTILVSYIIMFAYIAVSLGQVNTCSRLLIDSKITLGLGGVLIVLASVVSSVGLFGFVGLPATLIIIEVIPFLVLAVGVDNIFILVQTHQR-----EGKKPTETHAQHIGRTLGQVGPSMLLTSVSESCCFFLGSLSDMPAVKAFALYAGMALLFDFLLQITCFVSLLSLDTIRQASNRFDI-CCFIKGSKKEI------VQTNQEGLLYSFFKSIYVPLLMNRFVRAF-VMIVFFGWLCSSIAVVPHIEIGLDQELSMPEDSYVLKYFKFLKDDLSIGPPMYFVVKD-GLNYSDPKAQNVICGGQYCDLDSLITQVFEASKVPERTYIARPSSSWLDDYIDWAAAAKTCCKYNKTTGAFCPHTKGTCATCNISYLPLNHRPTPNDFEHYVSFFLQDNPDETCAKAGHAAYSQGVNYATNKTTHLSKVGASYFMAYHTILKTSKDYYESMRSARKVSANITNTINTKIPSSQIEVFPYSVFYVFYEQYLTMWPDTLQSMAISLAAIFVVTFLLMGLDFFSSAVVVITITMIVVNLGGLMYWWHITLNAVSLVNLVMAVGIAVEFCSHLVHSFSVSLKTTRVERAADSLTRMGSSIF-SGITLTKFGGIIVLGFAKSQIFQVFYFRMYLGIVLFGAAHGLIFLPVLLSY 1328
BLAST of EMLSAG00000004370 vs. Select Arthropod Genomes
Match: gb|KYB26017.1| (Niemann-Pick C1 protein-like Protein [Tribolium castaneum]) HSP 1 Score: 452.595 bits (1163), Expect = 3.020e-140 Identity = 314/1039 (30.22%), Postives = 538/1039 (51.78%), Query Frame = 0
Query: 27 KSCACLDXKQACP---KLDADEYKEILTLKNEYMNFPIAYSVLIVILLLMLLVGIFLIAIKIKAKN-----RISSETQEESRKESIGWLLFQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYN---NLYGKEA-----TFSXIFRQEMFYQVLKLQKEIEKIITEDKITLQDVCYKPL------APEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFV----KWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSWSN--DCCM-VDSQGKICI---------------------LFSNFMAF--------------HTVLRTSNDFV------QAIESTRILSD--------------KFAR--ENNITS---------FPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIMGKR-----SAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
++C+C+D + +C + + YK+ + + +F IA VL+ I + + F++ +I K+ R ++ + ++ + I L +T FR G F SK + VLI + + I L+ G+ +L V ++P+ELW++ +SRSR+E +FF+ +F+PF+RT+ + I N + F YN +L + TF F +V KLQ IE I D L+ +C PL +I C +QS+ + S + +D Y++ C+ +P+++ CL+ P+ +GG D +++ A+ +TFL++NH++++ ++ A++WE+ F+ +W E F ++IA+ AE SIQD I S ++ V ISY +MF+Y++FAL + + F I + I G+ +VLGS+L++ GL G+ G+ T++ E++PFLVLAVG+DNIF++V T +RK L+ ++ ++ IG T+ ++ P+ML+++ ++ F +G LS MPAV TFA+YA ++ NFL QIT F+A+ +LDLKR ++ ++++F C K + P + KT ++P++M V+ V++L I L +++ ++ +GLD + +MP+ S+V YF+++ +GPPVY+V ++ + ++Q ++CG C+ S T + + +LTT+AT SWIDD+ W+N DCC G C F+ F++F H + +FV IES+ ++S K+AR +N+T FPYSIF+ Y+EQYL++ D L S+ LL + ++ + +SG + T+ V I+I + G + I NAI VNL+++ GI+VE C + I + A + + + ++SGI +T G+ VL F++S IF +FF +Y+ IV+IG +HGLI LPVLLSF
Sbjct: 228 QACSCIDCEASCSNSVQFEDLSYKDFIFGNVQRDSF-IAACVLLTIGFVSI---NFIVYFRIVKKSLFPIFRKENKKKTKTIQAKISSYL-ETGFRNWGIFMSKQRIIVLIISILGIIALTVGIIFLDVITDPVELWAAPHSRSRQEKNFFDTNFQPFYRTNQIFIKTVN---IDPFVYNQTIDLGNNKTDILSHTFGPAFNATFLKEVFKLQTLIENITLGDGSGLESICLAPLVTVFSGPKDISVCAVQSLLGLFGNDASKLD---------EDDYVETFIKCLSSPYSV--------DCLAPYGGPVLPGLALGGNTFDNYTDAI----------AVSLTFLVENHLDENDLQAALEWEEKFIDLMKRWDEFVKPEF--MEIAYSAERSIQDEIARTSSSEIGTVTISYVVMFIYIAFALGRYTSSDRFLVETKICVGIGGVLIVLGSVLASIGLCGYAGISTTLLTIEVIPFLVLAVGVDNIFIIVQTHQRKQLN---EKLSLEEEIGETMAKVGPSMLLTSCSEIFCFAIGALSTMPAVNTFAIYATFAIFFNFLLQITAFVALFTLDLKRYRANRMEIFFCEKAKTSPEDIGPGIVYKIWKT-------NITPLIM-NFPVRCVVLLLFLIWLCVSIAVMPSLELGLDQQLSMPEDSHVLTYFKFMNDLMGIGPPVYWVAKG-KVNYSVPENQAKMCGGIFCESNSISTQLYQAYRQSNLTTMATEASSWIDDFRDWANATDCCFYFKENGTFCPHTLQRYCEPCNYGIMNLNESEYFTQFVSFFLMDNPDAKCAKGGHASYASGINFVLNQEGKATIESSNMMSYHTVLKGSTDYINALKYARYIGDNLTKTLDIPDVEIFPYSIFYTYFEQYLTIWEDALESLGLSLLVVFVVAFAISGLNLFAACTTLIVVLMIVIDMMGLMYFWNINFNAISLVNLVMSVGIAVEFCGHIVHHYIHSSKLSPLEKASDAFAEMGSSVLSGITLTKFSGIIVLAFARSQIFQIFFFRMYLGIVIIGALHGLIFLPVLLSF 1217
BLAST of EMLSAG00000004370 vs. Select Arthropod Genomes
Match: EAA06340.6 (AGAP000579-PA [Anopheles gambiae str. PEST]) HSP 1 Score: 434.876 bits (1117), Expect = 2.844e-133 Identity = 312/1046 (29.83%), Postives = 527/1046 (50.38%), Query Frame = 0
Query: 13 PEYLFCQLIIILN-----SKSCACLDXKQACPKLDADEYKEILTLKNEYMNFPIAYSVLIVILLLMLLVGIFLIAIKIKAKNRISSETQEESRKESIGWLLFQTFFRKLGYFCSKYAVYVL-ICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDKITLQDVCYKPLAPE-----IPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFVKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW--SNDCCMVD-SQGKICI-----------------------LFSNFMAFHTVLRTSNDFVQAIES--TRILS---DKFARENNITSFPYSIFH---VYYEQ-YLSMKTDTLV--------------------SIAYVLLTMLLICW--------------FLSGKIVIGLYTVTFVSSILIHVTGFISMLG------IQLNAILAVNLLVACGISVEICIGYLTSVIMGKRSAEEVYNDQAGILM--------SGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
PE F Q + N S +C+C+D ++CP + + K+ + + +V++ + L +V L K +K ++ S+ L +TF R G FC++ V +L IC+ I+ L+ G+ +L +T++P+ELW++ +SR+R+E D+F+ F PF+RT + I P+ + F F + G + TF + +E +V KLQ IE++ + L+ +C+ P+ + C +QSV+ Y++ S + FN T+ G YLD + C N + SC P+E +GGF P + D T +++TFL++N KD + A++WE+ FV ++ + E+ P++++A+ AE SI+D I+ S ++ VIISY +MFVY++F+L R + F I LA+ GI +VL S+ + G FG++ + TM+ E++PFLVLAVG+DNIF+LV R + E R E IG L +I P++L+++ ++ C F +G LS MPAV TFA YA +LL++FL QI+ F+A+++LD +R++ +LDL CC+ + + D P + + + E++ P L++ V+ +V+ L + S++L+ +I GLD E +M + S+V KYF ++ + +GPPVYFVV + ++ V+ QN +CG C+ S T + S P+ T +A SW+DDY W CC + + G C F ++ F + +A + +R L+ D+ R N S+ +S +H V Q Y +++ L+ S+ YV L W F+ +V GL ++ + IL+ ++M+G I LNAI VNL+++ GI VE +++ ++ R A +++ M SGI +T G+ VL F++S IF ++F +Y+ IV++G HGLI+LPV L++
Sbjct: 210 PEQRFNQEVKHCNEAYDGSYACSCVDCDESCPTSEPPQPKDPGFMVGDLNGVTFTVAVVVGGIGLACIVLALLFGGKEGSKQQLPDLPSFFGGFPSVNRALGRTFTR-WGTFCARNPVLILAICSWIVG-GLAFGIQYLIITTDPVELWAAPDSRARQEKDYFDSRFSPFYRTEQIFIKPTRQEF---FIHPTAEGNQ-TFGPAYDREFLLEVFKLQTTIEQLGQAEGRGLEQICFAPMTQVGAQTVLSECTVQSVFGYFKNSLAEFNRTGTDLNGFVVNYLDKINGCTRNAYL--------PSCFGTYGGPIEPGVAVGGFP---QPAPGANPDFRLAT-GVVLTFLVENKANKDELGPALEWEQRFVDFMR-DFEH-PMMEVAYSAERSIEDGIDEMSEAEMYTVIISYVVMFVYITFSLGKIRGFRQFLHGSRIVLAVGGIVVVLASVACSLGFFGYLELATTMLTIEVIPFLVLAVGVDNIFMLVHAFNR--IDRE-RTPETACAIGEALGQIGPSILLTSASECCCFAIGALSPMPAVNTFAWYATVALLVDFLLQISAFVALMALDEQRVERGRLDLVCCV--RATKNPDKPVAP-DGPGWLERVVERFYVPFLLRP-RVRLTVLALFLVWGSLSLMVVPSIEPGLDQELSMAEDSHVVKYFRFMAELFWMGPPVYFVVKA-GLNYTDVQHQNLVCGGILCNDDSISTKLYQASLYPETTHIARPASSWLDDYIDWLAIQSCCKYNPTDGSFCASNIVFCPACPEEYDETGIRPTVPQFERYLEFFLSDLPDENCAKAGRAAYSRALNYLLDRDGRLNVQDSY-FSTYHTTAVTSRQFYTALEQARLIAADIQQMLDERQAGVEIFPYSVFYVFYEQYLTIWSDALQSLGLSLAAVFVVTFLVTGLDLLSALVVILLVFLIVLNMMGLMWLWNITLNAISLVNLVMSVGIGVE----FISHIVRTYRLAHGTRLERSAAAMVRTGSSVFSGITLTKFAGIIVLAFAKSQIFQIFYFRMYLCIVLVGAAHGLILLPVFLTY 1222
BLAST of EMLSAG00000004370 vs. Select Arthropod Genomes
Match: EFX69947.1 (hypothetical protein DAPPUDRAFT_328579 [Daphnia pulex]) HSP 1 Score: 433.335 bits (1113), Expect = 6.281e-132 Identity = 267/788 (33.88%), Postives = 423/788 (53.68%), Query Frame = 0
Query: 13 PEYLFCQLIIILNSKSCACLDXKQACPKLDADEYKEILTLKNEYMNFPIAYSVLIVILLLMLLV-GIFLIAIKIK---------AKNR-------------ISSETQEESRKESIGWLL---FQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDKITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITND-RGHQDTYLDHLTTCVENP---------FTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFVK----WIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRK-LLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW--SNDCC--MVDSQGK 751
P + C +I +S +C+C+D +C + E Y V V+L++ L V G FL+ + K K R E E S E G + ++FF G FC+++ VLI + L+ GV +L+VT +P+ELW+S SRSR+E D+F++ F PF+RT +I+ ++ F Y L G + F F+ + +VL LQ +IE ++ ++ L D+CY P+ P++ C +QSV +WQG ++ G+ TYLDH C +NP + ++ T C+++ P V+GGF+ ++ ES+ E + N +ALI+TF++QN KD++ A WEK F++ W ++ + + + +A++AE SI+D + S DV+ + ISY +MF Y++ AL R+ ITL I G+ +VL S++++ G +G++GV AT+II E++PFLVLAVG+DNIF+LV T +R+ + E E + ++G E+AP+ML+S++++ F+LG LS MPAV FALYAG +LL+ FL Q+T FI + SLD R +S +LD+FCC+ + D PK + + F+ +P ++ K ++ VMV+ L ++ T + VGLD E +MP+ SY+ YF +L Y SVG PVYFVV +N + +Q ++CG GCD S T + L S + +A + SWIDDY W ++CC +D G+
Sbjct: 307 PPAIPCYEVISNSSGTCSCVDCTGSC------PVPKPWPPLPEPWTIGSMYGVSFVMLMVFLAVSGTFLVTVFWKWHVDQVARGVKRRSLQPTISTTSSTDSQYEYVEGSFMERAGASMEKALESFFTAWGTFCARWPWMVLIFGLSVAAALTVGVVFLEVTIDPVELWASPESRSRQEKDYFDKSFTPFYRTEQVILHAEG---IEGFDYETLSGTK-RFGPAFQLDFLLEVLHLQHDIEALMGDNGTHLNDICYMPMKPDVNECTIQSVLGWWQGREDYLLKSVVGTTNGYNYTYLDHAIYCSKNPLMPYDNNFKWQNENGTLEQIGCMAEYGGPAFPYVVLGGFRNGEN-ESVTDESLYMNATALILTFIVQNIANKDQLGPAKDWEKKFLEYMKFWKKNKMPKY--MSVAYMAERSIEDELTRASQSDVITIAISYCIMFAYIAIALGQARSFSRLLVDSKITLGIGGVIIVLLSVVASIGFYGYVGVPATLIIIEVIPFLVLAVGVDNIFILVQTYQREPRRANETHEEHIGRIVG----EVAPSMLLSSISEAFCFFLGALSGMPAVKAFALYAGMALLLAFLLQMTCFIGLFSLDTARQESNRLDIFCCVQVGKKND---PKDAAAAKGALYKLFQHAYAPFILSK-PMRAIVMVVFFGWLCASVALTPRVEVGLDQELSMPEDSYMLDYFSYLAKYLSVGAPVYFVVKESNFNYTDQLAQKKLCGGRGCDADSLVTQIYLASKNKSRSYIAATPASWIDDYLDWFRISECCKTKLDEHGE 1073 HSP 2 Score: 137.502 bits (345), Expect = 6.310e-32 Identity = 84/215 (39.07%), Postives = 127/215 (59.07%), Query Frame = 0
Query: 759 FMAFHTVLRTSNDFVQAIESTRILSDKFAR------ENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIMG------KRSAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
FM +HT+LRTS DF ++ R+++D + +N+ FPYSIF+VYYEQYL+M D LVS++ + + ++ + L G I + + + IL+ + G + + I LNA+ VNL++A GISVE C + + M RS E + + +L SGI +T G+ VL F++S IF ++F +Y+ IV+IG HGLI LPVLLSF
Sbjct: 1144 FMTYHTILRTSKDFYSSLIEARVIADSISETLSNITNSNVEVFPYSIFYVYYEQYLTMWRDVLVSLSISIGAIFVVTFILLGLDIHSSVVVLITIIMILVDLFGLMYLWDITLNAVSLVNLVMAVGISVEFCSHIVRAFAMSIEPTRIARSKESLVRMGSSVL-SGITLTKFGGIVVLAFAKSQIFQVFYFRMYLGIVLIGAAHGLIFLPVLLSF 1357
BLAST of EMLSAG00000004370 vs. Select Arthropod Genomes
Match: EFX76733.1 (hypothetical protein DAPPUDRAFT_321920 [Daphnia pulex]) HSP 1 Score: 429.869 bits (1104), Expect = 6.923e-131 Identity = 263/789 (33.33%), Postives = 425/789 (53.87%), Query Frame = 0
Query: 13 PEYLFCQLIIILNSKSCACLDXKQACPKLDADEYKEILTLKNEYMNFPIAYSVLIVILLLMLLV-GIFLIAIKIKAK-NRISSETQEESRK---------------------ESIGWLL---FQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDKITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITND-RGHQDTYLDHLTTCVENP---------FTIKSSTAMGQ-SCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFVK----WIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRK-LLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW--SNDCC--MVDSQGK 751
P + C I S +C+C+D +C + E Y V V+L++ L V G FL+ + K +R++ + S + E G + ++FF G FC+++ VLI + L+ GV +L+VT +P+ELW+S SRSR+E D+F++ F PF+RT +I+ ++ F Y L G + F F+ + + L LQ +IE ++ ++ L D+CY P+ P++ C +QSV +WQG ++ G+ TYLDH C +NP + +++ A+ Q C+++ P V+GGF+ ++ ES+ E + N +ALI+TF++QN +KD++ A WEK F++ W E+ + + + +A++AE SI+D + S DV+ + ISY +MF Y++ AL R+ ITL I G+ +VL S++++ G +G++GV AT+II E++PFLVLAVG+DNIF+LV T +R+ + E E + ++G E+AP+ML+S++++ F+LG LS MPAV FALYAG +LL++FL Q+T FI + SLD R +S +LD+ CC+ + D PK + + F+ +P ++ K ++ VMV+ L ++ T + VGLD E +MP+ SY+ YF +L Y SVG PVYFVV + + +Q ++CG GCD S T + L S + +A + SWIDDY W ++CC +D G+
Sbjct: 264 PPAIPCYEAISNTSGACSCVDCTGSC------PVPKPWPPLPEPWTIGSMYGVSFVMLMVFLAVSGTFLVTVFWKWHVDRVARGVKRRSLQPTISTTSSTDSQYEYVEGSFMERAGASMEKALESFFTAWGTFCARWPWMVLIFGLSVAAALTVGVVFLEVTIDPVELWASPESRSRQEKDYFDKSFTPFYRTEQVILHAEG---IEGFDYETLSGTK-RFGPAFQLDFLLEALHLQHDIEALMGDNGTHLNDICYMPMKPDVNECTIQSVLGWWQGREDYLLKSVVGTTNGYNYTYLDHAIYCSKNPLMPYDNNFKWQNETTGALEQIGCMAEYGGPAFPYVVLGGFRNGEN-ESVTDESLYMNATALILTFIVQNIADKDQLGPAKDWEKKFLEYMKFWKENKMPKY--MSVAYMAERSIEDELTRASQSDVITIAISYCIMFAYIAIALGQARSFSRLLVDSKITLGIGGVIIVLLSVVASIGFYGYVGVPATLIIIEVIPFLVLAVGVDNIFILVQTYQREPRRANETHEEHIGRIVG----EVAPSMLLSSISEAFCFFLGALSGMPAVKAFALYAGMALLLDFLLQMTCFIGLFSLDTARQESNRLDICCCVQVGKKND---PKDAAAAEGALYKLFQDAYAPFILSK-PMRAIVMVVFFGWLCASVALTPRVEVGLDQELSMPEDSYMLDYFSYLAKYLSVGAPVYFVVKESKFNYTDQLAQQKLCGGRGCDADSLVTQIYLASKNKSRSYIAATPASWIDDYLDWFRISECCKTKLDEHGE 1031 HSP 2 Score: 134.42 bits (337), Expect = 6.529e-31 Identity = 85/215 (39.53%), Postives = 129/215 (60.00%), Query Frame = 0
Query: 759 FMAFHTVLRTSNDFVQAIESTRILSDKFARE-NNITS-----FPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIMG------KRSAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
FM +HT+LRTS DF ++ R+++D + +NIT+ FPYSIF+VYYEQYL+M D LVS++ + + ++ + L G I + + + IL+ + G + + I LNA+ VNL++A GISVE C + + + RS E + + +L SGI +T G+ VL F++S IF ++F +Y+ IV+IG HGLI LPVLLSF
Sbjct: 1102 FMTYHTILRTSKDFYSSLIEARVIADSISETLSNITNSKVEVFPYSIFYVYYEQYLTMWRDVLVSLSISIGAIFVVTFILLGLDIHSSVVVLITIIMILVDLFGLMYLWDITLNAVSLVNLVMAVGISVEFCSHIVRAFAVSIEPTRIARSKESLVRMGSSVL-SGITLTKFGGIVVLAFAKSQIFQVFYFRMYLGIVLIGAAHGLIFLPVLLSF 1315
BLAST of EMLSAG00000004370 vs. Select Arthropod Genomes
Match: gb|KFM58254.1| (Niemann-Pick C1 protein, partial [Stegodyphus mimosarum]) HSP 1 Score: 405.601 bits (1041), Expect = 2.035e-125 Identity = 233/666 (34.98%), Postives = 375/666 (56.31%), Query Frame = 0
Query: 106 WLLFQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKII---TEDKITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQD------TYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFVKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYFGIT----LAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARR-KLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIA-ITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSWSND---CCMVDSQGKIC 753
WL + F + G FC+ +L+ F++ +SG+ + V + P+ELWS+ NS++R+E D+F+ HF PF+RT +II ++ + G TFS +F + +Q+L LQ I + I +++C+ P+ C++QS N++Q ND H D YL+ L C NPF I+ G SCL + P+ +GG DK+ N SALI++F++QN+++ + + A+ WE+ F+++++ N N P ++ F AE SIQD ++ SH D + ++ISY +MF YVS L + + + L + G+ +VL S++S+ G+F + GV AT+II E++PFLVLAVG+DNIF++V +R K + E RE + ++G ++AP++L+++L ++ F+LG LS MPAV FA Y+G +L+I+FL QI+ F+A++SLD R ++ ++D+ CC I +D+P+S + + F++Y +P LMK + ++V A + LSI+++ +N VGLD + MPK SYV KYF L+ Y SVGPPVYFVV S + + V+ QN +C A C S T + S + T +A W+D++ SW+ND CC V + G C
Sbjct: 4 WL--KDVFTQWGVFCATNPALILLIGLAFFVMFASGLVFFTVRTNPVELWSAPNSQAREEKDYFDNHFGPFYRTEQVIITRKTKT--------PVIGDNLTFSSVFDRSFLHQILDLQNNITSLTAVQNNRTIRFENICFAPMTKH--KCMIQSAVNWFQ-----------NDHAHLDYYKNTEEYLEFLKNCTSNPFFIQKK---GLSCLGEYGGPIFPYVALGGVP-DKN---------YNNASALILSFMVQNYVKSEDNDDAVAWEERFIEFLK-NFSN-PDMEFTFSAERSIQDELDRESHSDEVTILISYMVMFAYVSITLGQYHSPSLICVKSKMLLGLTGVLIVLASVVSSLGIFSYFGVPATLIIIEVIPFLVLAVGVDNIFIMVQAYQRSKRRAFETREQHIGRIVG----QVAPSILVASLAESSCFFLGALSHMPAVHVFAFYSGLALVIDFLLQISCFVAVMSLDAAREEANRIDICCC------IKIDHPESVPERKGFLHKLFDEYYAPFLMKDIVRCLVLLVFSAWVCLSISVLGGIN--VGLDQKLAMPKDSYVLKYFSSLEEYLSVGPPVYFVVKS-GFNYSDVEDQNSLCSVAYCYRDSMVTQISDASKFSNRTYIAHPPLDWLDNFISWANDQTGCCRVYANGTFC 618 HSP 2 Score: 117.857 bits (294), Expect = 6.086e-26 Identity = 74/218 (33.94%), Postives = 120/218 (55.05%), Query Frame = 0
Query: 757 SNFMAFHTVLRTSNDFVQAIESTRILSDKFAR--------ENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSGKIVIGLYTVTF-VSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEIC------IGYLTSVIMGKRSAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLS 959
+++M +HT+L+TS+DF A+ R + + + FPYS+F+V+YEQY+++ D + +I L+ + ++ + L G + F + IL ++ G + I LNA+ VNL++A GISVE C + T +R+ V + + +L SGI +T G+ VL FS+S IF ++F +Y+ IV+IG HGLI LPV LS
Sbjct: 683 THYMTYHTILKTSDDFTNALRWARKIGKNITQTLHLFNVSDREAEVFPYSVFYVFYEQYITVIHDAIRNIIISLVDIFIVSFLLMGLDFHSAMIIVFTIFMILQNLMGLMFFWDISLNAVSLVNLMMAAGISVEFCSHIIRAFAFNTEGSKVERARSAVAHTGSSVL-SGITLTKFGGIVVLAFSKSQIFQVFYFRMYLGIVLIGAAHGLIFLPVFLS 899
BLAST of EMLSAG00000004370 vs. Select Arthropod Genomes
Match: AHN54311.1 (Niemann-Pick type C-1a, isoform G [Drosophila melanogaster]) HSP 1 Score: 407.912 bits (1047), Expect = 2.360e-123 Identity = 257/759 (33.86%), Postives = 420/759 (55.34%), Query Frame = 0
Query: 18 CQLIIILNSKSCACLDXKQACPKLDADEYK----EILTLKNEYMNFPIAYSVLIVILLLMLLVGIFLIAIKIKAK---NRISSE---TQEESRKESIGW---LLFQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDKITLQDVCYKPLAPE-----IPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFVKWI----ESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRN-KKYF---GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARR-KLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKS--QNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW---SNDCC 744
C + +C+C D +CP+ + + +I+ L + + + + ++ +L+ L+G FL + N +S E ++ +S E +G +TFF K G + + LI + ++L G+ ++++T++P++LW+S NS+SR E +FF+ F PF+R +II N L + +N G TF +F +E +VL LQ+ I++I + L+D+CY PL+ + + C++QS+W Y+ + + D G TYLD L C+ NP+ CL+ P++ +GGF + ++ LAN A+I+TFL++NH K +E A+ WEK FV+++ ++N+ + +DIAF +E SI+D + S DVL +++SY +MF+Y++ +L + K+ F ITL I G+ +VL S++S+ G+FG+IG+ AT+II E++PFLVLAVG+DNIF+LV T +R + E E +V ++G ++ P+ML+++L+++ F+LG LS MPAV FALYAG +L+I+FL QIT F+++ +LD KR + ++D+ C + K P S + + + FF P LMKK+ V+ SVMV+ L ++ I +GLD E MP+ S+V YF+ L ++GPPVYFV+ DLA S QN +C C+ S T + L S + T +A SWIDDYF W ++ CC
Sbjct: 234 CNQAVSSKLPACSCSDCDLSCPQGPPEPPRPEPFKIVGLDAYF----VIMAAVFLVGVLVFLMGSFLFTQDDNFQVDGNDVSDEMPYSENDSYFEKLGAHTETFLETFFTKWGTYFASNPGLTLIAGASLVVILGYGINFIEITTDPVKLWASPNSKSRLEREFFDTKFSPFYRLEQIIIKAVN---LPQIVHNTSNGP-YTFGPVFDREFLTKVLDLQEGIKEI-NANGTQLKDICYAPLSDDGSEIDVSQCVVQSIWGYFGDDRERLD-DHDEDNGFNVTYLDALYDCISNPYL----------CLAPYGGPVDPAIALGGFLPPGDQLTGSTKFELAN--AIILTFLVKNHHNKTDLENALTWEKKFVEFMTNYTKNNMSQY--MDIAFTSERSIEDELNRESQSDVLTILVSYLIMFMYIAISLGHVKEFKRVFIDSKITLGIGGVIIVLASVVSSVGVFGYIGLPATLIIVEVIPFLVLAVGVDNIFILVQTHQRDQRKPNETLEQQVGRILG----KVGPSMLLTSLSESFCFFLGGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRREENRMDICCFIKGK------KPDSITSNEGLLYKFFSSVYVPFLMKKI-VRASVMVIFFAWLCFSIAIAPRIDIGLDQELAMPQDSFVLHYFQSLNENLNIGPPVYFVLKG---DLAYTNSSDQNLVCAGQYCNDDSVLTQIYLASRHSNQTYIARPASSWIDDYFDWAAAASSCC 954 HSP 2 Score: 137.887 bits (346), Expect = 5.334e-32 Identity = 93/264 (35.23%), Postives = 144/264 (54.55%), Query Frame = 0
Query: 719 KPDLTTLATSGQSWIDDYFSWSNDCCMVDSQGKICILFSNFMAFHTVLRTSNDFVQAIESTRILSDK---------------FARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIMGK------RSAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
PD T A +G + +SN S ++ I S FMA+HT+L++S D+ A+ES R +S A + FPYS+F+V+YEQYL+M +DTL S+ +L++ ++ + L G + L V ++ I++++ G + I LNA+ VNL++A GISVE C + S K R+A+ + + + SGI +T G+ VL F++S IF ++F +Y+ IVVIG HGLI LPVLLS+
Sbjct: 1000 NPD-DTCAKAGHAAYGGAVRYSN------SHERLNIEASYFMAYHTILKSSADYFLALESARKISANITQMLQGRLMSNGVPMASALTVEVFPYSVFYVFYEQYLTMWSDTLQSMGISVLSIFVVTFVLMGFDVHSALVVVITITMIVVNLGGLMYYWNISLNAVSLVNLVMAVGISVEFCSHLVHSFATSKSVSQIDRAADSL-SKMGSSIFSGITLTKFAGILVLAFAKSQIFQVFYFRMYLGIVVIGAAHGLIFLPVLLSY 1255
BLAST of EMLSAG00000004370 vs. Select Arthropod Genomes
Match: AHN54310.1 (Niemann-Pick type C-1a, isoform F [Drosophila melanogaster]) HSP 1 Score: 407.912 bits (1047), Expect = 2.360e-123 Identity = 257/759 (33.86%), Postives = 420/759 (55.34%), Query Frame = 0
Query: 18 CQLIIILNSKSCACLDXKQACPKLDADEYK----EILTLKNEYMNFPIAYSVLIVILLLMLLVGIFLIAIKIKAK---NRISSE---TQEESRKESIGW---LLFQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDKITLQDVCYKPLAPE-----IPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFVKWI----ESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRN-KKYF---GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARR-KLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKS--QNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW---SNDCC 744
C + +C+C D +CP+ + + +I+ L + + + + ++ +L+ L+G FL + N +S E ++ +S E +G +TFF K G + + LI + ++L G+ ++++T++P++LW+S NS+SR E +FF+ F PF+R +II N L + +N G TF +F +E +VL LQ+ I++I + L+D+CY PL+ + + C++QS+W Y+ + + D G TYLD L C+ NP+ CL+ P++ +GGF + ++ LAN A+I+TFL++NH K +E A+ WEK FV+++ ++N+ + +DIAF +E SI+D + S DVL +++SY +MF+Y++ +L + K+ F ITL I G+ +VL S++S+ G+FG+IG+ AT+II E++PFLVLAVG+DNIF+LV T +R + E E +V ++G ++ P+ML+++L+++ F+LG LS MPAV FALYAG +L+I+FL QIT F+++ +LD KR + ++D+ C + K P S + + + FF P LMKK+ V+ SVMV+ L ++ I +GLD E MP+ S+V YF+ L ++GPPVYFV+ DLA S QN +C C+ S T + L S + T +A SWIDDYF W ++ CC
Sbjct: 234 CNQAVSSKLPACSCSDCDLSCPQGPPEPPRPEPFKIVGLDAYF----VIMAAVFLVGVLVFLMGSFLFTQDDNFQVDGNDVSDEMPYSENDSYFEKLGAHTETFLETFFTKWGTYFASNPGLTLIAGASLVVILGYGINFIEITTDPVKLWASPNSKSRLEREFFDTKFSPFYRLEQIIIKAVN---LPQIVHNTSNGP-YTFGPVFDREFLTKVLDLQEGIKEI-NANGTQLKDICYAPLSDDGSEIDVSQCVVQSIWGYFGDDRERLD-DHDEDNGFNVTYLDALYDCISNPYL----------CLAPYGGPVDPAIALGGFLPPGDQLTGSTKFELAN--AIILTFLVKNHHNKTDLENALTWEKKFVEFMTNYTKNNMSQY--MDIAFTSERSIEDELNRESQSDVLTILVSYLIMFMYIAISLGHVKEFKRVFIDSKITLGIGGVIIVLASVVSSVGVFGYIGLPATLIIVEVIPFLVLAVGVDNIFILVQTHQRDQRKPNETLEQQVGRILG----KVGPSMLLTSLSESFCFFLGGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRREENRMDICCFIKGK------KPDSITSNEGLLYKFFSSVYVPFLMKKI-VRASVMVIFFAWLCFSIAIAPRIDIGLDQELAMPQDSFVLHYFQSLNENLNIGPPVYFVLKG---DLAYTNSSDQNLVCAGQYCNDDSVLTQIYLASRHSNQTYIARPASSWIDDYFDWAAAASSCC 954 HSP 2 Score: 137.887 bits (346), Expect = 5.334e-32 Identity = 93/264 (35.23%), Postives = 144/264 (54.55%), Query Frame = 0
Query: 719 KPDLTTLATSGQSWIDDYFSWSNDCCMVDSQGKICILFSNFMAFHTVLRTSNDFVQAIESTRILSDK---------------FARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIMGK------RSAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
PD T A +G + +SN S ++ I S FMA+HT+L++S D+ A+ES R +S A + FPYS+F+V+YEQYL+M +DTL S+ +L++ ++ + L G + L V ++ I++++ G + I LNA+ VNL++A GISVE C + S K R+A+ + + + SGI +T G+ VL F++S IF ++F +Y+ IVVIG HGLI LPVLLS+
Sbjct: 1000 NPD-DTCAKAGHAAYGGAVRYSN------SHERLNIEASYFMAYHTILKSSADYFLALESARKISANITQMLQGRLMSNGVPMASALTVEVFPYSVFYVFYEQYLTMWSDTLQSMGISVLSIFVVTFVLMGFDVHSALVVVITITMIVVNLGGLMYYWNISLNAVSLVNLVMAVGISVEFCSHLVHSFATSKSVSQIDRAADSL-SKMGSSIFSGITLTKFAGILVLAFAKSQIFQVFYFRMYLGIVVIGAAHGLIFLPVLLSY 1255
BLAST of EMLSAG00000004370 vs. nr
Match: gi|478250629|gb|ENN71121.1| (hypothetical protein YQE_12054, partial [Dendroctonus ponderosae]) HSP 1 Score: 519.62 bits (1337), Expect = 3.928e-165 Identity = 321/942 (34.08%), Postives = 501/942 (53.18%), Query Frame = 0
Query: 110 QTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSN-ESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDKITLQDVCYKPLAPE-----IPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFV----KWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSWS--NDCCM-------------VDSQGKICIL-------------FSNFMAF-------------------HTVLRTSN------------------------DFVQAIESTRILSDKFARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIMGKRS-----AEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
Q FF K G FC++ VL + + L G+ +LKVT++P+ELW+S +SRSR E ++F+ HF+PF+R +II N +S + N+ TF F +VL LQ++I+ I +++C+ PL + + C +QSVW Y+Q S +F T+ Q YLD L C+ NP+ C + P++ GGF KS E+L + +A+I+TFL+ N+ K ++ A++WEK FV + ESN+ + +DIAF +E SI+D ++ S GDV+ ++ISY +MF Y++ +L + ITL + G+ +VL S++S+ GLFGF+G AT+II E++PFLVLAVG+DNIF+LV T +R + + IG TL ++ P+ML+++++++ F+LG+LS MPAV FALYAG +LL +F+ QIT F+++LSLD R S + D+FCCL + + DN S+ + + TFF+ +MKK ++ +M++ L ++ +I +GLD E +MP+ S+V KYF++LK Y S+GPP+YFVV + ++ + K QN +CG C+ S T + + S P+ T +A SW+DDY W+ CC D Q + C + F +++F H V SN D+ +++ R +S + + FPYS+F+V+YEQYL+M DTL S+ LL + L +FL G I + + ++ IL+++ G + I LNA+ VNL++A GISVE C + S M ++ A + + SGI +T G+ VL F++S IF ++F +Y+ IV+ G HGLI LPVLLSF
Sbjct: 52 QKFFEKWGTFCAERPWLVLFFGTCVIVALGHGIKYLKVTTDPVELWASPSSRSRVEKEYFDSHFDPFYRNEQVIIRAKNLKSIIHPTSLGNV-----TFGPAFNDTFLLEVLDLQEKIKAIGGGTDYAYENICFAPLRTDEDEASLDQCAVQSVWGYFQDSIETFEETGTDPDHFQINYLDALLKCMSNPYNT--------DCFALYGGPVDPAIAFGGFL--KSGENLPKSPKYEDATAVILTFLVNNYHNKSKIVAAMEWEKHFVAFMKNYTESNVSQY--MDIAFTSERSIEDELDRESQGDVITILISYLIMFAYIAVSLGQVNSCSRLLIDSKITLGLGGVIIVLASVVSSVGLFGFVGTPATLIIIEVIPFLVLAVGVDNIFILVQTHQRDVKKPGETHAQ---HIGRTLGQVGPSMLLTSVSESSCFFLGSLSDMPAVRAFALYAGMALLFDFIFQITCFVSLLSLDTIRQNSNRFDIFCCLRGSKKNEPDNLTSQ---EGLLFTFFKSVYVGFIMKK-PMRVLIMIVFFGWLCSSIAVVPHIEIGLDQELSMPEDSFVLKYFKFLKDYLSIGPPMYFVVKN-GLNYSEFKDQNLVCGGQYCNVDSLITQVYMASKDPENTYIAKPSSSWLDDYIDWTAIESCCKKRVADGGFCPHESYDPQCQACGIALNNRTHRPKPEEFERYISFFLQDNPDATCAKAGHAAYSHAVNYASNRKTNLSNVGASYFMSYHSILKTSADYYESMRKARTISANLTKSVGVEVFPYSVFYVFYEQYLTMWPDTLQSLGISLLAIFLATFFLMGLDIFSSIVVLITITMILVNLGGLMYWWHITLNAVSLVNLVMAVGISVEFCSHLVHSFSMSVKTTRVDRAADALAKMGSSIFSGITLTKFGGIIVLYFAKSQIFQVFYFRMYLGIVLFGAAHGLIFLPVLLSF 968
BLAST of EMLSAG00000004370 vs. nr
Match: gi|1130262884|ref|XP_019770256.1| (PREDICTED: Niemann-Pick C1 protein isoform X4 [Dendroctonus ponderosae]) HSP 1 Score: 520.776 bits (1340), Expect = 2.053e-162 Identity = 341/1071 (31.84%), Postives = 549/1071 (51.26%), Query Frame = 0
Query: 7 SFVSLIPEYLFCQLIIILNSKSCACLDXKQACPKLDADEYKEILTLKNEYMNFPIA-YSVLIVILLLMLLVG--IFLIAIKIKAKNR---ISSETQEESRKESIGWL--------------------LFQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSN-ESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDKITLQDVCYKPLAPE-----IPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFV----KWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSWS--NDCCM-------------VDSQGKICIL-------------FSNFMAF-------------------HTVLRTSN------------------------DFVQAIESTRILSDKFARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIMGKRS-----AEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
+F + E C + ++ +C+C+D + +C + F IA + + ++L++ ++G +FL+ + + + R I+SE + E S+ + Q FF K G FC++ VL + + L G+ +LKVT++P+ELW+S +SRSR E ++F+ HF+PF+R +II N +S + N+ TF F +VL LQ++I+ I +++C+ PL + + C +QSVW Y+Q S +F T+ Q YLD L C+ NP+ C + P++ GGF KS E+L + +A+I+TFL+ N+ K ++ A++WEK FV + ESN+ + +DIAF +E SI+D ++ S GDV+ ++ISY +MF Y++ +L + ITL + G+ +VL S++S+ GLFGF+G AT+II E++PFLVLAVG+DNIF+LV T +R + + IG TL ++ P+ML+++++++ F+LG+LS MPAV FALYAG +LL +F+ QIT F+++LSLD R S + D+FCCL + + DN S+ + + TFF+ +MKK ++ +M++ L ++ +I +GLD E +MP+ S+V KYF++LK Y S+GPP+YFVV + ++ + K QN +CG C+ S T + + S P+ T +A SW+DDY W+ CC D Q + C + F +++F H V SN D+ +++ R +S + + FPYS+F+V+YEQYL+M DTL S+ LL + L +FL G I + + ++ IL+++ G + I LNA+ VNL++A GISVE C + S M ++ A + + SGI +T G+ VL F++S IF ++F +Y+ IV+ G HGLI LPVLLSF
Sbjct: 231 NFTPMDIEITPCNKPLNSDTPACSCVDCEDSC--------PVPPPDPPKPQPFHIAGFEGMSFLMLVVFVIGSIVFLLIVFMCSAGRTFGITSELEHEMDMHSVSKVPGEYDTPSSFIERLGANTDSCLQKFFEKWGTFCAERPWLVLFFGTCVIVALGHGIKYLKVTTDPVELWASPSSRSRVEKEYFDSHFDPFYRNEQVIIRAKNLKSIIHPTSLGNV-----TFGPAFNDTFLLEVLDLQEKIKAIGGGTDYAYENICFAPLRTDEDEASLDQCAVQSVWGYFQDSIETFEETGTDPDHFQINYLDALLKCMSNPYNTD--------CFALYGGPVDPAIAFGGFL--KSGENLPKSPKYEDATAVILTFLVNNYHNKSKIVAAMEWEKHFVAFMKNYTESNVSQY--MDIAFTSERSIEDELDRESQGDVITILISYLIMFAYIAVSLGQVNSCSRLLIDSKITLGLGGVIIVLASVVSSVGLFGFVGTPATLIIIEVIPFLVLAVGVDNIFILVQTHQRDVKKPGETHAQ---HIGRTLGQVGPSMLLTSVSESSCFFLGSLSDMPAVRAFALYAGMALLFDFIFQITCFVSLLSLDTIRQNSNRFDIFCCLRGSKKNEPDNLTSQ---EGLLFTFFKSVYVGFIMKK-PMRVLIMIVFFGWLCSSIAVVPHIEIGLDQELSMPEDSFVLKYFKFLKDYLSIGPPMYFVVKN-GLNYSEFKDQNLVCGGQYCNVDSLITQVYMASKDPENTYIAKPSSSWLDDYIDWTAIESCCKKRVADGGFCPHESYDPQCQACGIALNNRTHRPKPEEFERYISFFLQDNPDATCAKAGHAAYSHAVNYASNRKTNLSNVGASYFMSYHSILKTSADYYESMRKARTISANLTKSVGVEVFPYSVFYVFYEQYLTMWPDTLQSLGISLLAIFLATFFLMGLDIFSSIVVLITITMILVNLGGLMYWWHITLNAVSLVNLVMAVGISVEFCSHLVHSFSMSVKTTRVDRAADALAKMGSSIFSGITLTKFGGIIVLYFAKSQIFQVFYFRMYLGIVLFGAAHGLIFLPVLLSF 1268
BLAST of EMLSAG00000004370 vs. nr
Match: gi|546679528|gb|ERL89983.1| (hypothetical protein D910_07342 [Dendroctonus ponderosae]) HSP 1 Score: 518.464 bits (1334), Expect = 1.570e-161 Identity = 321/942 (34.08%), Postives = 500/942 (53.08%), Query Frame = 0
Query: 110 QTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSN-ESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDKITLQDVCYKPLAPE-----IPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFV----KWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSWS--NDCCM-------------VDSQGKICIL-------------FSNFMAF-------------------HTVLRTSN------------------------DFVQAIESTRILSDKFARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIMGKRS-----AEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
Q FF K G FC++ VL + + L G+ +LKVT++P+ELW+S +SRSR E ++F+ HF+PF+R +II N +S + N+ TF F +VL LQ+ I+ I +++C+ PL + + C +QSVW Y+Q S +F T+ Q YLD L C+ NP+ C + P++ GGF KS E+L + +A+I+TFL+ N+ K ++ A++WEK FV + ESN+ + +DIAF +E SI+D ++ S GDV+ ++ISY +MF Y++ +L + ITL + G+ +VL S++S+ GLFGF+G AT+II E++PFLVLAVG+DNIF+LV T +R + + IG TL ++ P+ML+++++++ F+LG+LS MPAV FALYAG +LL +F+ QIT F+++LSLD R S + D+FCCL + + DN S+ + + TFF+ +MKK ++ +M++ L ++ +I +GLD E +MP+ S+V KYF++LK Y S+GPP+YFVV + ++ + K QN +CG C+ S T + + S P+ T +A SW+DDY W+ CC D Q + C + F +++F H V SN D+ +++ R +S + + FPYS+F+V+YEQYL+M DTL S+ LL + L +FL G I + + ++ IL+++ G + I LNA+ VNL++A GISVE C + S M ++ A + + SGI +T G+ VL F++S IF ++F +Y+ IV+ G HGLI LPVLLSF
Sbjct: 360 QKFFEKWGTFCAERPWLVLFFGTCVIVALGHGIKYLKVTTDPVELWASPSSRSRVEKEYFDSHFDPFYRNEQVIIRAKNLKSIIHPTSLGNV-----TFGPAFNDTFLLEVLDLQERIKAIGGGTDYAYENICFAPLRTDEDEASLDQCAVQSVWGYFQDSIETFEETGTDPDHFQINYLDALLKCMSNPYNTD--------CFALYGGPVDPAIAFGGFL--KSGENLPKSPKYEDATAVILTFLVNNYHNKSKIVAAMEWEKHFVAFMKNYTESNVSQY--MDIAFTSERSIEDELDRESQGDVITILISYLIMFAYIAVSLGQVNSCSRLLIDSKITLGLGGVIIVLASVVSSVGLFGFVGTPATLIIIEVIPFLVLAVGVDNIFILVQTHQRDVKKPGETHAQ---HIGRTLGQVGPSMLLTSVSESSCFFLGSLSDMPAVRAFALYAGMALLFDFIFQITCFVSLLSLDTIRQNSNRFDIFCCLRGSKKNEPDNLTSQ---EGLLFTFFKSVYVGFIMKK-PMRVLIMIVFFGWLCSSIAVVPHIEIGLDQELSMPEDSFVLKYFKFLKDYLSIGPPMYFVVKN-GLNYSEFKDQNLVCGGQYCNVDSLITQVYMASKDPENTYIAKPSSSWLDDYIDWTAIESCCKKRVADGGFCPHESYDPQCQACGIALNNRTHRPKPEEFERYISFFLQDNPDATCAKAGHAAYSHAVNYASNRKTNLSNVGASYFMSYHSILKTSADYYESMRKARTISANLTKSVGVEVFPYSVFYVFYEQYLTMWPDTLQSLGISLLAIFLATFFLMGLDIFSSIVVLITITMILVNLGGLMYWWHITLNAVSLVNLVMAVGISVEFCSHLVHSFSMSVKTTRVDRAADALAKMGSSIFSGITLTKFGGIIVLYFAKSQIFQVFYFRMYLGIVLFGAAHGLIFLPVLLSF 1276
BLAST of EMLSAG00000004370 vs. nr
Match: gi|1130262878|ref|XP_019770254.1| (PREDICTED: Niemann-Pick C1 protein isoform X2 [Dendroctonus ponderosae]) HSP 1 Score: 518.079 bits (1333), Expect = 4.825e-161 Identity = 321/942 (34.08%), Postives = 501/942 (53.18%), Query Frame = 0
Query: 110 QTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSN-ESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDKITLQDVCYKPLAPE-----IPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFV----KWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSWS--NDCCM-------------VDSQGKICIL-------------FSNFMAF-------------------HTVLRTSN------------------------DFVQAIESTRILSDKFARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIMGKRS-----AEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
Q FF K G FC++ VL + + L G+ +LKVT++P+ELW+S +SRSR E ++F+ HF+PF+R +II N +S + N+ TF F +VL LQ++I+ I +++C+ PL + + C +QSVW Y+Q S +F T+ Q YLD L C+ NP+ C + P++ GGF KS E+L + +A+I+TFL+ N+ K ++ A++WEK FV + ESN+ + +DIAF +E SI+D ++ S GDV+ ++ISY +MF Y++ +L + ITL + G+ +VL S++S+ GLFGF+G AT+II E++PFLVLAVG+DNIF+LV T +R + + IG TL ++ P+ML+++++++ F+LG+LS MPAV FALYAG +LL +F+ QIT F+++LSLD R S + D+FCCL + + DN S+ + + TFF+ +MKK ++ +M++ L ++ +I +GLD E +MP+ S+V KYF++LK Y S+GPP+YFVV + ++ + K QN +CG C+ S T + + S P+ T +A SW+DDY W+ CC D Q + C + F +++F H V SN D+ +++ R +S + + FPYS+F+V+YEQYL+M DTL S+ LL + L +FL G I + + ++ IL+++ G + I LNA+ VNL++A GISVE C + S M ++ A + + SGI +T G+ VL F++S IF ++F +Y+ IV+ G HGLI LPVLLSF
Sbjct: 428 QKFFEKWGTFCAERPWLVLFFGTCVIVALGHGIKYLKVTTDPVELWASPSSRSRVEKEYFDSHFDPFYRNEQVIIRAKNLKSIIHPTSLGNV-----TFGPAFNDTFLLEVLDLQEKIKAIGGGTDYAYENICFAPLRTDEDEASLDQCAVQSVWGYFQDSIETFEETGTDPDHFQINYLDALLKCMSNPYNTD--------CFALYGGPVDPAIAFGGFL--KSGENLPKSPKYEDATAVILTFLVNNYHNKSKIVAAMEWEKHFVAFMKNYTESNVSQY--MDIAFTSERSIEDELDRESQGDVITILISYLIMFAYIAVSLGQVNSCSRLLIDSKITLGLGGVIIVLASVVSSVGLFGFVGTPATLIIIEVIPFLVLAVGVDNIFILVQTHQRDVKKPGETHAQ---HIGRTLGQVGPSMLLTSVSESSCFFLGSLSDMPAVRAFALYAGMALLFDFIFQITCFVSLLSLDTIRQNSNRFDIFCCLRGSKKNEPDNLTSQ---EGLLFTFFKSVYVGFIMKK-PMRVLIMIVFFGWLCSSIAVVPHIEIGLDQELSMPEDSFVLKYFKFLKDYLSIGPPMYFVVKN-GLNYSEFKDQNLVCGGQYCNVDSLITQVYMASKDPENTYIAKPSSSWLDDYIDWTAIESCCKKRVADGGFCPHESYDPQCQACGIALNNRTHRPKPEEFERYISFFLQDNPDATCAKAGHAAYSHAVNYASNRKTNLSNVGASYFMSYHSILKTSADYYESMRKARTISANLTKSVGVEVFPYSVFYVFYEQYLTMWPDTLQSLGISLLAIFLATFFLMGLDIFSSIVVLITITMILVNLGGLMYWWHITLNAVSLVNLVMAVGISVEFCSHLVHSFSMSVKTTRVDRAADALAKMGSSIFSGITLTKFGGIIVLYFAKSQIFQVFYFRMYLGIVLFGAAHGLIFLPVLLSF 1344
BLAST of EMLSAG00000004370 vs. nr
Match: gi|1130262881|ref|XP_019770255.1| (PREDICTED: Niemann-Pick C1 protein isoform X3 [Dendroctonus ponderosae]) HSP 1 Score: 518.079 bits (1333), Expect = 4.986e-161 Identity = 321/942 (34.08%), Postives = 501/942 (53.18%), Query Frame = 0
Query: 110 QTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSN-ESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDKITLQDVCYKPLAPE-----IPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFV----KWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSWS--NDCCM-------------VDSQGKICIL-------------FSNFMAF-------------------HTVLRTSN------------------------DFVQAIESTRILSDKFARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIMGKRS-----AEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
Q FF K G FC++ VL + + L G+ +LKVT++P+ELW+S +SRSR E ++F+ HF+PF+R +II N +S + N+ TF F +VL LQ++I+ I +++C+ PL + + C +QSVW Y+Q S +F T+ Q YLD L C+ NP+ C + P++ GGF KS E+L + +A+I+TFL+ N+ K ++ A++WEK FV + ESN+ + +DIAF +E SI+D ++ S GDV+ ++ISY +MF Y++ +L + ITL + G+ +VL S++S+ GLFGF+G AT+II E++PFLVLAVG+DNIF+LV T +R + + IG TL ++ P+ML+++++++ F+LG+LS MPAV FALYAG +LL +F+ QIT F+++LSLD R S + D+FCCL + + DN S+ + + TFF+ +MKK ++ +M++ L ++ +I +GLD E +MP+ S+V KYF++LK Y S+GPP+YFVV + ++ + K QN +CG C+ S T + + S P+ T +A SW+DDY W+ CC D Q + C + F +++F H V SN D+ +++ R +S + + FPYS+F+V+YEQYL+M DTL S+ LL + L +FL G I + + ++ IL+++ G + I LNA+ VNL++A GISVE C + S M ++ A + + SGI +T G+ VL F++S IF ++F +Y+ IV+ G HGLI LPVLLSF
Sbjct: 400 QKFFEKWGTFCAERPWLVLFFGTCVIVALGHGIKYLKVTTDPVELWASPSSRSRVEKEYFDSHFDPFYRNEQVIIRAKNLKSIIHPTSLGNV-----TFGPAFNDTFLLEVLDLQEKIKAIGGGTDYAYENICFAPLRTDEDEASLDQCAVQSVWGYFQDSIETFEETGTDPDHFQINYLDALLKCMSNPYNTD--------CFALYGGPVDPAIAFGGFL--KSGENLPKSPKYEDATAVILTFLVNNYHNKSKIVAAMEWEKHFVAFMKNYTESNVSQY--MDIAFTSERSIEDELDRESQGDVITILISYLIMFAYIAVSLGQVNSCSRLLIDSKITLGLGGVIIVLASVVSSVGLFGFVGTPATLIIIEVIPFLVLAVGVDNIFILVQTHQRDVKKPGETHAQ---HIGRTLGQVGPSMLLTSVSESSCFFLGSLSDMPAVRAFALYAGMALLFDFIFQITCFVSLLSLDTIRQNSNRFDIFCCLRGSKKNEPDNLTSQ---EGLLFTFFKSVYVGFIMKK-PMRVLIMIVFFGWLCSSIAVVPHIEIGLDQELSMPEDSFVLKYFKFLKDYLSIGPPMYFVVKN-GLNYSEFKDQNLVCGGQYCNVDSLITQVYMASKDPENTYIAKPSSSWLDDYIDWTAIESCCKKRVADGGFCPHESYDPQCQACGIALNNRTHRPKPEEFERYISFFLQDNPDATCAKAGHAAYSHAVNYASNRKTNLSNVGASYFMSYHSILKTSADYYESMRKARTISANLTKSVGVEVFPYSVFYVFYEQYLTMWPDTLQSLGISLLAIFLATFFLMGLDIFSSIVVLITITMILVNLGGLMYWWHITLNAVSLVNLVMAVGISVEFCSHLVHSFSMSVKTTRVDRAADALAKMGSSIFSGITLTKFGGIIVLYFAKSQIFQVFYFRMYLGIVLFGAAHGLIFLPVLLSF 1316
BLAST of EMLSAG00000004370 vs. nr
Match: gi|1059380984|ref|XP_017782952.1| (PREDICTED: Niemann-Pick C1 protein isoform X5 [Nicrophorus vespilloides]) HSP 1 Score: 516.153 bits (1328), Expect = 1.172e-160 Identity = 343/1060 (32.36%), Postives = 532/1060 (50.19%), Query Frame = 0
Query: 26 SKSCACLDXKQACPKLDADEYKEILTLKNEYMNFPIAYSVLIVILLLMLLVG-IFLIAIKIKAKNR---ISSETQEESRKESIGWL---------------------LFQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDKITLQDVCYKPLA------PEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFVKWIESNLENFP--LLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQT----AMKL-------------------WSTKPDLTTLATSGQSWIDDYFSWSNDC--CMV----------------------DSQGKIC------------------------ILFSNFMAFHTVLRTSNDFVQAIESTRILS-----------DKFARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTS-----VIMGKRSAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
+ +CAC+D +++CP E L Y + V++ ++ +VG + I + + NR ++SET E SI + Q FF + G +C+ +VL + I L G+ +LKVT++P+ELW+S +SRSR E + F+ HFEPF+R +II LQ + G E F +F + V LQ++I+ I +L +C+ PL ++ C +QSVW Y+Q +F ++ G YLD TC +NPF CL + P++ GGF K E L +++A+I+TFL+ N+ K ++ A++WE FVK++++ E+ +DIAF E SI+D ++ S DVL ++ISY +MF Y++ +L +TL + G+ +VL S++S+ G+FGF G+ AT+II E++PFLVLAVG+DNIF+LV T +R+L E IG L ++ P+ML++++++ C F+LG+LS MPAV FALYAG +LL +FL QIT F+ +LSLD +R + K D+ CC+ K N + + +FF++ P LM K V+ VM++ L +L +I +GLD E +MP+ S+V KYF++LK Y S+GPP+YFVV S ++ + + QN IC CD S T A K+ WS+ P TS + + S SN C CM+ D+ C + S FMA+H++L+TS D+ +++ + R +S K + ++ FPYS+F+V+YEQYL+M DTL S+ LL + + + L G I + V ++ I+I++ G + I LNA+ VNL++A GISVE C + S K+ A + + SGI +T G+ VL F++S IF ++F +Y+ IVV+G HGLI LPVLLS+
Sbjct: 252 NPACACMDCEESCPVPKPPPPAEGPFLIGGYDGY-------AVVMTIVFVVGSVLFITANVLSNNRCSSVTSETDHELDTHSINKMPGEYDVVSSSFLEKLGANTDTYLQRFFERWGVYCASRPWFVLFLGACLVIALGHGIKYLKVTTDPVELWASPSSRSRVEREIFDSHFEPFYRNEQIIIRAVG---LQPVVHETSIG-ELKFGPVFNETFLRAVFDLQEKIKLIGANTGHSLDKICFAPLRNKDTKDTDVTQCAIQSVWGYFQDDVDTFEETDEDENGFVVNYLDRFITCTQNPFN--------PDCLGQYGGPVDPAIAFGGFL--KPGEHLSKHSQYKDSTAIILTFLVNNYHNKTKLSPAMEWESDFVKFMKNYTEHGKPEFMDIAFTTERSIEDELDRESQSDVLTILISYVIMFAYIAVSLGQLNKCNRVLIDSKVTLGLGGVVIVLASVISSVGIFGFFGLPATLIIIEVIPFLVLAVGVDNIFILVQTHQRELRKPNETHAE---HIGRILGQVGPSMLLTSVSECCCFFLGSLSDMPAVRAFALYAGMALLFDFLLQITCFVGLLSLDTQRQVNNKFDICCCIQGK-----KNSDEGAQSEGLLYSFFKEIYVPFLMNKY-VRTGVMIIFFGWLCSSLAVAPHIEIGLDQELSMPEDSFVLKYFKFLKDYLSIGPPMYFVV-SAGLNYSQTEQQNMICSGLYCDLDSLVTQVFVASKMPTTSYISKPSNSWIDDYFDWSSIPSCCKYDTSTGGFCP-HESTSNKCDRCMITTEKNSRPNATGFEKYVSFFLQDNPDATCAKGGHAAYGQGVDYATNSTTGLSTVGASYFMAYHSILKTSEDYYESMRAARTISKNITDTINGKLQKMGVKESVEVFPYSVFYVFYEQYLTMWPDTLQSMGISLLAIFVCTFLLMGLDIFSSVVVVITIAMIVINLGGVMYWWHITLNAVSLVNLVMAVGISVEFCSHLVHSFSVSVAATRKQRAADCLTRMGSSVFSGITLTKFGGIVVLAFAKSQIFQVFYFRMYLGIVVLGAAHGLIFLPVLLSY 1279
BLAST of EMLSAG00000004370 vs. nr
Match: gi|1130262874|ref|XP_019770253.1| (PREDICTED: Niemann-Pick C1 protein isoform X1 [Dendroctonus ponderosae]) HSP 1 Score: 517.694 bits (1332), Expect = 1.226e-160 Identity = 321/942 (34.08%), Postives = 501/942 (53.18%), Query Frame = 0
Query: 110 QTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSN-ESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDKITLQDVCYKPLAPE-----IPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFV----KWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSWS--NDCCM-------------VDSQGKICIL-------------FSNFMAF-------------------HTVLRTSN------------------------DFVQAIESTRILSDKFARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIMGKRS-----AEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
Q FF K G FC++ VL + + L G+ +LKVT++P+ELW+S +SRSR E ++F+ HF+PF+R +II N +S + N+ TF F +VL LQ++I+ I +++C+ PL + + C +QSVW Y+Q S +F T+ Q YLD L C+ NP+ C + P++ GGF KS E+L + +A+I+TFL+ N+ K ++ A++WEK FV + ESN+ + +DIAF +E SI+D ++ S GDV+ ++ISY +MF Y++ +L + ITL + G+ +VL S++S+ GLFGF+G AT+II E++PFLVLAVG+DNIF+LV T +R + + IG TL ++ P+ML+++++++ F+LG+LS MPAV FALYAG +LL +F+ QIT F+++LSLD R S + D+FCCL + + DN S+ + + TFF+ +MKK ++ +M++ L ++ +I +GLD E +MP+ S+V KYF++LK Y S+GPP+YFVV + ++ + K QN +CG C+ S T + + S P+ T +A SW+DDY W+ CC D Q + C + F +++F H V SN D+ +++ R +S + + FPYS+F+V+YEQYL+M DTL S+ LL + L +FL G I + + ++ IL+++ G + I LNA+ VNL++A GISVE C + S M ++ A + + SGI +T G+ VL F++S IF ++F +Y+ IV+ G HGLI LPVLLSF
Sbjct: 428 QKFFEKWGTFCAERPWLVLFFGTCVIVALGHGIKYLKVTTDPVELWASPSSRSRVEKEYFDSHFDPFYRNEQVIIRAKNLKSIIHPTSLGNV-----TFGPAFNDTFLLEVLDLQEKIKAIGGGTDYAYENICFAPLRTDEDEASLDQCAVQSVWGYFQDSIETFEETGTDPDHFQINYLDALLKCMSNPYNTD--------CFALYGGPVDPAIAFGGFL--KSGENLPKSPKYEDATAVILTFLVNNYHNKSKIVAAMEWEKHFVAFMKNYTESNVSQY--MDIAFTSERSIEDELDRESQGDVITILISYLIMFAYIAVSLGQVNSCSRLLIDSKITLGLGGVIIVLASVVSSVGLFGFVGTPATLIIIEVIPFLVLAVGVDNIFILVQTHQRDVKKPGETHAQ---HIGRTLGQVGPSMLLTSVSESSCFFLGSLSDMPAVRAFALYAGMALLFDFIFQITCFVSLLSLDTIRQNSNRFDIFCCLRGSKKNEPDNLTSQ---EGLLFTFFKSVYVGFIMKK-PMRVLIMIVFFGWLCSSIAVVPHIEIGLDQELSMPEDSFVLKYFKFLKDYLSIGPPMYFVVKN-GLNYSEFKDQNLVCGGQYCNVDSLITQVYMASKDPENTYIAKPSSSWLDDYIDWTAIESCCKKRVADGGFCPHESYDPQCQACGIALNNRTHRPKPEEFERYISFFLQDNPDATCAKAGHAAYSHAVNYASNRKTNLSNVGASYFMSYHSILKTSADYYESMRKARTISANLTKSVGVEVFPYSVFYVFYEQYLTMWPDTLQSLGISLLAIFLATFFLMGLDIFSSIVVLITITMILVNLGGLMYWWHITLNAVSLVNLVMAVGISVEFCSHLVHSFSMSVKTTRVDRAADALAKMGSSIFSGITLTKFGGIIVLYFAKSQIFQVFYFRMYLGIVLFGAAHGLIFLPVLLSF 1344
BLAST of EMLSAG00000004370 vs. nr
Match: gi|1059380982|ref|XP_017782942.1| (PREDICTED: Niemann-Pick C1 protein isoform X4 [Nicrophorus vespilloides]) HSP 1 Score: 509.22 bits (1310), Expect = 7.298e-158 Identity = 341/1076 (31.69%), Postives = 533/1076 (49.54%), Query Frame = 0
Query: 26 SKSCACLDXKQACPKLDADEYKEILTLKNEYMNFPIAYSVLIVILLLMLLVG--------------------IFLIAIKIKAKNRISSETQEESRKESIGWL---------------------LFQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDKITLQDVCYKPLA------PEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFVKWIESNLENFP--LLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQT----AMKL-------------------WSTKPDLTTLATSGQSWIDDYFSWSNDC--CMV----------------------DSQGKIC------------------------ILFSNFMAFHTVLRTSNDFVQAIESTRILS-----------DKFARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTS-----VIMGKRSAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
+ +CAC+D +++CP E L Y + + +++ V+ ++ + + L+AI + ++SET E SI + Q FF + G +C+ +VL + I L G+ +LKVT++P+ELW+S +SRSR E + F+ HFEPF+R +II LQ + G E F +F + V LQ++I+ I +L +C+ PL ++ C +QSVW Y+Q +F ++ G YLD TC +NPF CL + P++ GGF K E L +++A+I+TFL+ N+ K ++ A++WE FVK++++ E+ +DIAF E SI+D ++ S DVL ++ISY +MF Y++ +L +TL + G+ +VL S++S+ G+FGF G+ AT+II E++PFLVLAVG+DNIF+LV T +R+L E IG L ++ P+ML++++++ C F+LG+LS MPAV FALYAG +LL +FL QIT F+ +LSLD +R + K D+ CC+ K N + + +FF++ P LM K V+ VM++ L +L +I +GLD E +MP+ S+V KYF++LK Y S+GPP+YFVV S ++ + + QN IC CD S T A K+ WS+ P TS + + S SN C CM+ D+ C + S FMA+H++L+TS D+ +++ + R +S K + ++ FPYS+F+V+YEQYL+M DTL S+ LL + + + L G I + V ++ I+I++ G + I LNA+ VNL++A GISVE C + S K+ A + + SGI +T G+ VL F++S IF ++F +Y+ IVV+G HGLI LPVLLS+
Sbjct: 252 NPACACMDCEESCPVPKPPPPAEGPFLIGGYDGYAVVMTIVFVVGSVLFITANVLSNNRCSSSILVQKNVQEVELLAI-YRHNQGVTSETDHELDTHSINKMPGEYDVVSSSFLEKLGANTDTYLQRFFERWGVYCASRPWFVLFLGACLVIALGHGIKYLKVTTDPVELWASPSSRSRVEREIFDSHFEPFYRNEQIIIRAVG---LQPVVHETSIG-ELKFGPVFNETFLRAVFDLQEKIKLIGANTGHSLDKICFAPLRNKDTKDTDVTQCAIQSVWGYFQDDVDTFEETDEDENGFVVNYLDRFITCTQNPFN--------PDCLGQYGGPVDPAIAFGGFL--KPGEHLSKHSQYKDSTAIILTFLVNNYHNKTKLSPAMEWESDFVKFMKNYTEHGKPEFMDIAFTTERSIEDELDRESQSDVLTILISYVIMFAYIAVSLGQLNKCNRVLIDSKVTLGLGGVVIVLASVISSVGIFGFFGLPATLIIIEVIPFLVLAVGVDNIFILVQTHQRELRKPNETHAE---HIGRILGQVGPSMLLTSVSECCCFFLGSLSDMPAVRAFALYAGMALLFDFLLQITCFVGLLSLDTQRQVNNKFDICCCIQGK-----KNSDEGAQSEGLLYSFFKEIYVPFLMNKY-VRTGVMIIFFGWLCSSLAVAPHIEIGLDQELSMPEDSFVLKYFKFLKDYLSIGPPMYFVV-SAGLNYSQTEQQNMICSGLYCDLDSLVTQVFVASKMPTTSYISKPSNSWIDDYFDWSSIPSCCKYDTSTGGFCP-HESTSNKCDRCMITTEKNSRPNATGFEKYVSFFLQDNPDATCAKGGHAAYGQGVDYATNSTTGLSTVGASYFMAYHSILKTSEDYYESMRAARTISKNITDTINGKLQKMGVKESVEVFPYSVFYVFYEQYLTMWPDTLQSMGISLLAIFVCTFLLMGLDIFSSVVVVITIAMIVINLGGVMYWWHITLNAVSLVNLVMAVGISVEFCSHLVHSFSVSVAATRKQRAADCLTRMGSSVFSGITLTKFGGIVVLAFAKSQIFQVFYFRMYLGIVVLGAAHGLIFLPVLLSY 1301
BLAST of EMLSAG00000004370 vs. nr
Match: gi|1059380980|ref|XP_017782936.1| (PREDICTED: Niemann-Pick C1 protein isoform X3 [Nicrophorus vespilloides]) HSP 1 Score: 506.523 bits (1303), Expect = 1.291e-156 Identity = 322/951 (33.86%), Postives = 493/951 (51.84%), Query Frame = 0
Query: 110 QTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDKITLQDVCYKPLA------PEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFVKWIESNLENFP--LLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQT----AMKL-------------------WSTKPDLTTLATSGQSWIDDYFSWSNDC--CMV----------------------DSQGKIC------------------------ILFSNFMAFHTVLRTSNDFVQAIESTRILS-----------DKFARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTS-----VIMGKRSAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
Q FF + G +C+ +VL + I L G+ +LKVT++P+ELW+S +SRSR E + F+ HFEPF+R +II LQ + G E F +F + V LQ++I+ I +L +C+ PL ++ C +QSVW Y+Q +F ++ G YLD TC +NPF CL + P++ GGF K E L +++A+I+TFL+ N+ K ++ A++WE FVK++++ E+ +DIAF E SI+D ++ S DVL ++ISY +MF Y++ +L +TL + G+ +VL S++S+ G+FGF G+ AT+II E++PFLVLAVG+DNIF+LV T +R+L E IG L ++ P+ML++++++ C F+LG+LS MPAV FALYAG +LL +FL QIT F+ +LSLD +R + K D+ CC+ K N + + +FF++ P LM K V+ VM++ L +L +I +GLD E +MP+ S+V KYF++LK Y S+GPP+YFVV S ++ + + QN IC CD S T A K+ WS+ P TS + + S SN C CM+ D+ C + S FMA+H++L+TS D+ +++ + R +S K + ++ FPYS+F+V+YEQYL+M DTL S+ LL + + + L G I + V ++ I+I++ G + I LNA+ VNL++A GISVE C + S K+ A + + SGI +T G+ VL F++S IF ++F +Y+ IVV+G HGLI LPVLLS+
Sbjct: 397 QRFFERWGVYCASRPWFVLFLGACLVIALGHGIKYLKVTTDPVELWASPSSRSRVEREIFDSHFEPFYRNEQIIIRAVG---LQPVVHETSIG-ELKFGPVFNETFLRAVFDLQEKIKLIGANTGHSLDKICFAPLRNKDTKDTDVTQCAIQSVWGYFQDDVDTFEETDEDENGFVVNYLDRFITCTQNPFN--------PDCLGQYGGPVDPAIAFGGFL--KPGEHLSKHSQYKDSTAIILTFLVNNYHNKTKLSPAMEWESDFVKFMKNYTEHGKPEFMDIAFTTERSIEDELDRESQSDVLTILISYVIMFAYIAVSLGQLNKCNRVLIDSKVTLGLGGVVIVLASVISSVGIFGFFGLPATLIIIEVIPFLVLAVGVDNIFILVQTHQRELRKPNETHAE---HIGRILGQVGPSMLLTSVSECCCFFLGSLSDMPAVRAFALYAGMALLFDFLLQITCFVGLLSLDTQRQVNNKFDICCCIQGK-----KNSDEGAQSEGLLYSFFKEIYVPFLMNKY-VRTGVMIIFFGWLCSSLAVAPHIEIGLDQELSMPEDSFVLKYFKFLKDYLSIGPPMYFVV-SAGLNYSQTEQQNMICSGLYCDLDSLVTQVFVASKMPTTSYISKPSNSWIDDYFDWSSIPSCCKYDTSTGGFCP-HESTSNKCDRCMITTEKNSRPNATGFEKYVSFFLQDNPDATCAKGGHAAYGQGVDYATNSTTGLSTVGASYFMAYHSILKTSEDYYESMRAARTISKNITDTINGKLQKMGVKESVEVFPYSVFYVFYEQYLTMWPDTLQSMGISLLAIFVCTFLLMGLDIFSSVVVVITIAMIVINLGGVMYWWHITLNAVSLVNLVMAVGISVEFCSHLVHSFSVSVAATRKQRAADCLTRMGSSVFSGITLTKFGGIVVLAFAKSQIFQVFYFRMYLGIVVLGAAHGLIFLPVLLSY 1322
BLAST of EMLSAG00000004370 vs. nr
Match: gi|1059380978|ref|XP_017782929.1| (PREDICTED: Niemann-Pick C1 protein isoform X2 [Nicrophorus vespilloides]) HSP 1 Score: 506.138 bits (1302), Expect = 1.479e-156 Identity = 322/951 (33.86%), Postives = 493/951 (51.84%), Query Frame = 0
Query: 110 QTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDKITLQDVCYKPLA------PEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFVKWIESNLENFP--LLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQT----AMKL-------------------WSTKPDLTTLATSGQSWIDDYFSWSNDC--CMV----------------------DSQGKIC------------------------ILFSNFMAFHTVLRTSNDFVQAIESTRILS-----------DKFARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTS-----VIMGKRSAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
Q FF + G +C+ +VL + I L G+ +LKVT++P+ELW+S +SRSR E + F+ HFEPF+R +II LQ + G E F +F + V LQ++I+ I +L +C+ PL ++ C +QSVW Y+Q +F ++ G YLD TC +NPF CL + P++ GGF K E L +++A+I+TFL+ N+ K ++ A++WE FVK++++ E+ +DIAF E SI+D ++ S DVL ++ISY +MF Y++ +L +TL + G+ +VL S++S+ G+FGF G+ AT+II E++PFLVLAVG+DNIF+LV T +R+L E IG L ++ P+ML++++++ C F+LG+LS MPAV FALYAG +LL +FL QIT F+ +LSLD +R + K D+ CC+ K N + + +FF++ P LM K V+ VM++ L +L +I +GLD E +MP+ S+V KYF++LK Y S+GPP+YFVV S ++ + + QN IC CD S T A K+ WS+ P TS + + S SN C CM+ D+ C + S FMA+H++L+TS D+ +++ + R +S K + ++ FPYS+F+V+YEQYL+M DTL S+ LL + + + L G I + V ++ I+I++ G + I LNA+ VNL++A GISVE C + S K+ A + + SGI +T G+ VL F++S IF ++F +Y+ IVV+G HGLI LPVLLS+
Sbjct: 419 QRFFERWGVYCASRPWFVLFLGACLVIALGHGIKYLKVTTDPVELWASPSSRSRVEREIFDSHFEPFYRNEQIIIRAVG---LQPVVHETSIG-ELKFGPVFNETFLRAVFDLQEKIKLIGANTGHSLDKICFAPLRNKDTKDTDVTQCAIQSVWGYFQDDVDTFEETDEDENGFVVNYLDRFITCTQNPFN--------PDCLGQYGGPVDPAIAFGGFL--KPGEHLSKHSQYKDSTAIILTFLVNNYHNKTKLSPAMEWESDFVKFMKNYTEHGKPEFMDIAFTTERSIEDELDRESQSDVLTILISYVIMFAYIAVSLGQLNKCNRVLIDSKVTLGLGGVVIVLASVISSVGIFGFFGLPATLIIIEVIPFLVLAVGVDNIFILVQTHQRELRKPNETHAE---HIGRILGQVGPSMLLTSVSECCCFFLGSLSDMPAVRAFALYAGMALLFDFLLQITCFVGLLSLDTQRQVNNKFDICCCIQGK-----KNSDEGAQSEGLLYSFFKEIYVPFLMNKY-VRTGVMIIFFGWLCSSLAVAPHIEIGLDQELSMPEDSFVLKYFKFLKDYLSIGPPMYFVV-SAGLNYSQTEQQNMICSGLYCDLDSLVTQVFVASKMPTTSYISKPSNSWIDDYFDWSSIPSCCKYDTSTGGFCP-HESTSNKCDRCMITTEKNSRPNATGFEKYVSFFLQDNPDATCAKGGHAAYGQGVDYATNSTTGLSTVGASYFMAYHSILKTSEDYYESMRAARTISKNITDTINGKLQKMGVKESVEVFPYSVFYVFYEQYLTMWPDTLQSMGISLLAIFVCTFLLMGLDIFSSVVVVITIAMIVINLGGVMYWWHITLNAVSLVNLVMAVGISVEFCSHLVHSFSVSVAATRKQRAADCLTRMGSSVFSGITLTKFGGIVVLAFAKSQIFQVFYFRMYLGIVVLGAAHGLIFLPVLLSY 1344
BLAST of EMLSAG00000004370 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold22_size673200-snap-gene-4.23 (protein:Tk12689 transcript:maker-scaffold22_size673200-snap-gene-4.23-mRNA-1 annotation:"niemann-pick c1 protein isoform x3") HSP 1 Score: 481.871 bits (1239), Expect = 4.631e-152 Identity = 283/750 (37.73%), Postives = 425/750 (56.67%), Query Frame = 0
Query: 28 SCACLDXKQACPKLDADEYKEILTLKNE-YMNFPIAYSVLIVILLLMLLVGIFLIAIKIKAKNRISSETQEESRK---------ESIGWLLFQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITEDKITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSF-NLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEKAIKWEKSFVKWIESNLE-NFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCL--SDKGE-IDVD-NPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTN----MDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSWSNDCCMVDSQGKIC 753
+C+C D ++AC D + ++ L +E N+ + +L + + L +G+F+ + ++ + +I +K +++ +F F+R G C+++A ++ + +V S G+F+++V ++P+ LWS+ SRSR E DFF FEPFFR +I+ P F Y NL+ + +FR E + L+L KE++ + T ++L D+C+KPLAP+ C +QS+W YWQ F I GH DTY+DH C NP + T M Q C+SKG VP++ FV+GGF KS S S+ +N +ALI+T L+ NH + A+ WEK+FV+++ + LE L++I F +E SIQD +E +S GD+ VV+ISY M VY+ +L +K F ITL++ G VL +I S G G++G+ T+IIF+I+PFL+LAVG+DNIF+LV T + L E +V +I + + ++ P++L+ST+ Q AF LG +S MPAV +F++YA +L NF+ Q+T FI L DL R + + D+FCCL S + E +D D P S F T E YV P L ++ K V+V A T + ++ +I VGL+ E MP S V +YF LK SVGPPVYFVVN T D + SQ++ICG GC+ Q +KLWS +P +T +AT QSWIDD+FSW+ CC D G+ C
Sbjct: 235 ACSCTDCERACQSPD---FGQVYHLSDEDSENYFDLWLLLGCLGIFFLSMGVFIGCLWMRHRTKIYPMMASGDKKTKAAASCGTQTLNKFMFDQFYR-WGLMCARHAAKIMALGFALVLVASGGIFFIEVETDPVRLWSAPTSRSRVEKDFFETAFEPFFRVEQIILKPKKND---PFMYRNLFEDDIQMGAVFRPEFMLETLRLLKEVQALTTSSGVSLSDICHKPLAPDQQECNIQSIWAYWQDDPDKFLESGINPTTGHNDTYIDHFLMCSNNPTLQQDQTFMKQGCMSKGGVPVQPVFVLGGFDLSKSNASQGSQQ-FSNPTALIVTILVNNH--PNDTHLAMDWEKTFVEFMNAQLEEGSDLMEITFNSERSIQDELERSSLGDIAVVLISYSTMLVYIMVSLGKIYSKSTFFVDIKITLSLIGTLGVLLAIASAIGTLGYLGLPTTLIIFQILPFLILAVGVDNIFILVNTVQSILE--EDSTKDVKEIIALAVAKVGPSILMSTVAQVTAFLLGGISDMPAVRSFSIYAAMALAWNFVLQMTIFIGALYWDLYRQCALRADIFCCLQRSPREEPLDGDFRPGSWFQRLWT-----ELYV-PFLFNQVVRKMVVVVFAAWTCA-SIWLIPHIRVGLEQEVAMPDDSQVLRYFNALKSDLSVGPPVYFVVNRTRPDSPFDFSLEASQDKICGGRGCNSDGLQAQIKLWSKEPRITRIATPAQSWIDDFFSWAKYCCQHDGLGQPC 965 HSP 2 Score: 141.739 bits (356), Expect = 2.027e-34 Identity = 83/217 (38.25%), Postives = 134/217 (61.75%), Query Frame = 0
Query: 757 SNFMAFHTVLRTSNDFVQAIESTRILSDKF-----ARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSGKIVIGLYTVTF-VSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYL------TSVIMGKRSAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSFF 961
S+F AFH+VLR SNDF +A+ +R L+D + + ++ FPYSIF+V+YEQYL+M +DTL+S+A ++ + L+ +G V + + L+++ G + +LGI LNAI VNL++ G+ VE + T G + + + +++G+H+TN IGV VL S+S IF YFF +Y+SIV++G +HGL++LPV+L+F+
Sbjct: 1052 SSFFAFHSVLRDSNDFTEALRWSRRLADNLTSMLNSGDQHVRVFPYSIFYVFYEQYLTMWSDTLISLAVAVVAVFLVVLAFTGLDVFSAVAIMVTILVTLVNMGGVMVILGIDLNAISLVNLVMTVGVGVEFSSHLVQAFRSYTDEPSGLVRSRKALVEWGPTILAGVHLTNAIGVVVLALSRSQIFHIYFFQMYMSIVILGMLHGLVLLPVILTFW 1268
BLAST of EMLSAG00000004370 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold609_size125094-snap-gene-0.22 (protein:Tk01016 transcript:maker-scaffold609_size125094-snap-gene-0.22-mRNA-1 annotation:"niemann-pick c1 isoform x7") HSP 1 Score: 452.981 bits (1164), Expect = 1.384e-137 Identity = 255/692 (36.85%), Postives = 409/692 (59.10%), Query Frame = 0
Query: 107 LLFQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQ-VLKLQKEIEKIITEDKITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNL-NITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQ-SCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILAN---TSALIMTFLLQN-------HIEKDRVEKAIKWEKSFVKWI---ESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREME-VDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNM--DLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW-SNDCCMVDSQGKICILFSNF-----MAFHTVLRTS 769
L + F + G FC+ Y V V++ + ++L SGV WLK+T++P+ELW++ SRSR E ++F+ F PF+RT+ +I N L F+Y + G E TF +F + F + +L+LQ+ I+ I T + LQDVC PL+P+ C +Q+VW YWQ S +F+L + G+ TYLDH TC NP + C+SKG +P++ FV+GGF PE + AN + A++M+ ++ N H + R+ KA +WEK+F++++ E N +N +D+AF +E SI+D + + GDV ++ISY +MFVY++ AL F + + ITL I+G+ +VL S+ ++ G+FGF +++T+IIFEI+PFLVLAVG+DNIF+LV T +R E + E + +G + E+ P+ML+S+L++ F+LG L+ MPAV +FAL AG ++LI+F QIT F+++ +LD+ R +S + D+ CC K++ + + FE++ +P ++ K ++ +V+V+ L +L ++ VGLD E +MP S+V KYFE++K Y SVGPP Y +++ ++ + + QNR+ GS G P S +K WS + D+T +A++ QSW+DDYFSW N C +Q + + SN+ + +H RT
Sbjct: 933 LTMERLFARWGTFCAYYPVPVIVFGVVAALILCSGVQWLKITTDPVELWAAPGSRSRSEKEYFDSTFRPFYRTAQVIAAAKN---LPDFEYTDADGIEQTFGPVFHADEFLKPLLRLQEAIQNITTASGLKLQDVCNAPLSPQDNVCNIQNVWAYWQDSEENFDLIRFDANTGNNLTYLDHFLTCARNPALPTDGNQVNPLGCMSKGGIPVQPFFVLGGFI----PEGVSGLPQNANYQGSKAVVMSIIVDNFDMYSTDHESQLRLTKAKEWEKAFIEFMKEWEKNPDNTQYMDVAFNSERSIEDELARQTQGDVKTIVISYAIMFVYITIALGQFTSFRTIMVESKITLGISGVLLVLLSVGASIGIFGFANIESTLIIFEIIPFLVLAVGVDNIFILVQTYQRS----ERKPYETLPEHVGRVVGEVGPSMLLSSLSEATCFFLGALTDMPAVYSFALNAGMAILIDFFMQITCFVSLTALDMYRQESHRYDIVCCAKASK-------KTKKAGKGVLYRLFEQFYAPFILSKW-LRPTVVVVFLAWLCSSLAVAPHLEVGLDQEISMPDDSFVLKYFEYMKDYLSVGPPFYITLDNKDLKFNFSDPAMQNRLSGSFGSLPDSLNAQVKQWSIRSDITYVASTAQSWLDDYFSWLRNSACCSYNQITLDVCQSNYQGDNELPWHPESRTG 1605 HSP 2 Score: 150.214 bits (378), Expect = 7.661e-37 Identity = 92/220 (41.82%), Postives = 127/220 (57.73%), Query Frame = 0
Query: 757 SNFMAFHTVLRTSNDFVQAIESTRILSD--------KFARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVI------MGKRSAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSFF 961
+NFM FHT+LRTS DF +A+ +R L+D E + F YS+F+VYYEQYL+M D+L ++ Y LL + + L G I L + + ILI++ G + IQLN + VNL+V GISVE C + S M KRS + N + +L SGI +T G+ VLGF++S IF +FF +Y+ IV+IG HGLI LPVLLS+
Sbjct: 1681 NNFMVFHTILRTSTDFSEALRWSRKLTDAIDETVNKDLGEEERLNIFAYSVFYVYYEQYLTMWEDSLETLGYSLLAVFCVTLVLLGLDIASALIVILVILMILINMIGLMYWWNIQLNGVTLVNLVVTIGISVEFCAHMVRSFSVTNESDMIKRSKATLVNMGSSVL-SGITLTKFGGIIVLGFAKSQIFKIFFFRMYLGIVIIGAAHGLIFLPVLLSYL 1899
BLAST of EMLSAG00000004370 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold28_size608977-snap-gene-1.19 (protein:Tk05739 transcript:maker-scaffold28_size608977-snap-gene-1.19-mRNA-1 annotation:"AGAP010394-PA") HSP 1 Score: 117.087 bits (292), Expect = 7.840e-27 Identity = 184/901 (20.42%), Postives = 368/901 (40.84%), Query Frame = 0
Query: 110 QTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMFYQVLKLQKEIEKIITE---DKITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKD-RVEKAIKWEKSFVKWIESNLEN--FPLLDIA-FIAEMSIQDAIESN-SHGDVLVVIISYFLMFVYVSFALTD-FRNKKYFGITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSD-----------------KGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYY-SVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSW------SNDCCM-VDSQGKICILFSNFMAFHTVLRTSNDFVQAIESTRILSDKFARENNITSFPY--------------------------SIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSGKIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVE----ICIGYLTSVIMGKRSAEEVYNDQAGILMSGIH--ITNLIGVSVLGFSQSNIFFYYFFTVYISIVV 944
+ F KLG+F ++ Y +I ++ + +SG +++ +P L+S T+ ++ E + HF T+ S S + KF + K+ I R ++ Q++ L + + + QDVC + + +L+ Q NL TY + NP+ ++ T A F +GG + + + I+ + A+ + + L + +D V WE+ ++ + SNL P L+I F++ + +S S ++L++ + ++F + + ++D R+K G + G+ + ++ G FIGV+ + PFL+L +GID+ FV++ + RR + V +G + A ++ +++LT +F G ++ P+V F L+ G S+ ++ T F AIL+L K + CC+ G I+ D+P + + + F + V + K VK V+ L + + I N+ GL+ +T SY Y++ LY+ + + N++ A V++Q +I + +++ + T QSW+ D+ + + D + +D++ K + T S D + +R+ S +F + + Y F +Y +QYL +K T+ + + M+++ L +V L+ + SI + V GF++ G+ L+ + +NL++ G SV+ IC Y+ GK + + G+ + + ++ ++GV+ LGF+ S +F +F +++ IV+
Sbjct: 11 KRMFYKLGHFIGEHPGYFIIIPILLTKLCASGFYFMDYQYDPEYLFSPTHGAAKLEREVLEAHFP----TNYSQFKSSRISRVGKFARLVIAPKDG--GSILRSSLWNQMIYLDQIVYNVTVSFEGQNYQYQDVCARWAGYCYDNEILRLADLIPQVEQGQINL----------TYPLYF-----NPYDFETVTM--------------AAF-LGGVEHGE-------DHIIKDAKAMSLAYFLD--VSEDWMVTVGDDWERQLLEDV-SNLSATYAPDLEIGRFVSNTPAWEMEKSRLSVTNILIINVIAMIIFSFGAALMSDNVRSKPVIGFS----GLLSAGMATIAAFGFACFIGVEFISLNMA-APFLLLGIGIDDTFVMLSSWRRS-----SGHLTVPERMGRCYSDAAVSITVTSLTDFLSFMAGAVTPFPSVRIFCLFTGISVAFIYIWHCTFFGAILALSGYGEKKNLHSICCCIKATPSSQALNRNFLFRWFMTGGINPDDPHNPRDNRDHAGMVFFRDVFGKFLTKTWVKSLVLCLFGVYIVIACWGVTNLKEGLEKRNTANYDSYSVSYYDMEDLYFKKYAFTISLMFTGPNINFADVRTQQKI-----------ENITRMFEDSVYIDGSVT--QSWLRDFLDYISRNGGTPDFDLSIDTEQKFATILREVYVADTDNPLSLDVEYTKDFSRVKSARFLIQGHNIKNSYMEQQMVMELRDICNRFSTDEMQIAVFQPFFIYIDQYLDIKPQTIQCVVATAIIMIIVSLLLIPSVVSSLWISFSIISIEVGVVGFMTWWGVSLDGVALINLIMCIGFSVDFSAHICYHYIAED--GKLPDDRIRGSLYGLGIPIVQGALSTVVGVAGLGFAPSYLFVTFFKMIFLVIVL 840
BLAST of EMLSAG00000004370 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold34_size539781-snap-gene-1.9 (protein:Tk05354 transcript:maker-scaffold34_size539781-snap-gene-1.9-mRNA-1 annotation:"hypothetical protein DAPPUDRAFT_306990") HSP 1 Score: 110.153 bits (274), Expect = 1.275e-24 Identity = 138/598 (23.08%), Postives = 265/598 (44.31%), Query Frame = 0
Query: 404 DVLVVIISYFLMFVYVSFALTDFRNKKYFGITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSI---TLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVG--------PPVYFVVNS------TNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSG--QSWIDDYFSWSNDCCMVDSQGKICILFSNFMAFHT----VLRTSNDF-------VQAIESTRILSDKFARENNITSFPYSIFHVYYEQYLSMKTDTLVS------IAYVLLTMLLICWFLSGKIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSVIMGKRSAEEVYNDQ-----AGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSF 960
D + + YFLMF Y L N +A GI V + G+ +G+ T I I+PFL L +GID++FV+V LS E ++ + IG+T++ A+ +++LT AF +G ++ +P + F + ++ ++ Q + F+A+LSLD +RI+ + C+ + I + ++ Y K F K ++KK F+ +V++ ITL + + T I DP +P SY++++ ++++ P+ + N ++++ + +I S F+T ++ D T+ G + ++ D+ V S+ K I+ + + + T++DF + R L + + +S +S V Y + +TD ++S +A ++ + +I L + I L ++ + L+ + GF+ G+ ++ I +N+++A G+ V+ + I+ + EE + IL G IT + + +LGFS+S+ F FF V++ V+ G HGL+ LPV+LS
Sbjct: 442 DAVKMAAGYFLMFFYTMLFLGKL-NLVEHRTWIAAGGIISVGMGLGIAFGVTSALGMPYTPI-HGILPFLALGIGIDDMFVIVQCWYN--LSPEEQQRTLPEKIGLTMKHAGVAITVTSLTDVFAFGVGAVTILPGLQAFCVTCAIAIAAIYILQASWFVALLSLDQRRIRDHRDGFAPCIRYRNWI--PSAWTQKEYGKMFMAGFAK-----ILKK---GFTKIVVLGITLGVFGTGIYGTYLIRQEFDPVLLLPAQSYLRQWLAVQEVHFPTNGWGANIYTGPLEDIENDLEQFEKLSLEMDALTKDGKILKSYDSWWVPFKTFIETKRNVTDWRTMVREGNFEMFLSDFL-----FSKVGSRYKPKIILEKELVCNQPASRITATNSDFSYVKFSGPEEHVPGRRLVENLIQGKKFSSKAFSFSKV----YAAWETDEVISFELWRNLALAMVCVFIITLVLLANVKICLMVLSCICLTLVDMVGFLHFWGLTIDTISCINIVLAIGLCVDYSAHIAHAFIVEEGDREERAMNSLVSMGPAILNGG--ITTFLALVLLGFSESHAFI-TFFKVFMLTVIFGLFHGLVYLPVILSL 1013
BLAST of EMLSAG00000004370 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold193_size270907-snap-gene-0.15 (protein:Tk01088 transcript:maker-scaffold193_size270907-snap-gene-0.15-mRNA-1 annotation:"hypothetical protein DAPPUDRAFT_306990") HSP 1 Score: 107.842 bits (268), Expect = 5.654e-24 Identity = 138/606 (22.77%), Postives = 255/606 (42.08%), Query Frame = 0
Query: 389 AEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFR--NKKYFGITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMD-----------LATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTL----------------ATSGQSWIDDY-FSWSNDCCMVDSQGKICILFSNFMAFHTVLRTSNDFVQAIESTRILSDKFARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSGKIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEIC--IGYLTSVIMGKRSA---EEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLS 959
A S D S GDV + I Y ++F +V L F ++ F L+ AGI V I++ G+ +G+ + I+PFL+L +GID++FV+V L+ E + + + G T++ A+ I+++T AF +G + +PA+ +F LYA ++ + Q T F+A +++D +RI++K+ CC N S+ +Y ++ T ++ K +K V++L + + + + D +P +Y+ K+F K Y+ G ++ N+D + +K Q I F M + PD L + G + + + F C SQ ++ S H V + + A+ + L + I FP S + +E + + ++ +L + + FL ++ + V LI V GF+ + ++ + A NL++A G+ V+ I + V G R+ + + N +L G + + +L S+S++ F FF ++ +V G HGL+ LPV+LS
Sbjct: 407 ARRSFGDVAGSTILGDVGKLGIGYTIVFFFVMIMLGRFNCVEQRAF---LSFAGIMGVGMGIITAYGVCSALGLFFGPM-HGILPFLLLGIGIDDMFVIVQCF--NTLTEEEKSLPLIDKFGATMQHAGVAITITSITDVIAFGIGGSTVIPALKSFCLYASVGIIATYFYQCTFFVAWMAIDQRRIEAKRDG--CCPCWTHSNWTPNALSQKDYLGSVFTAIGHGLT-----KGPIKILVIILTLAITGVAIWGNVLLEQEFDITWFLPPDTYIAKWFVKNKEYFPFGGD-RVIIYCHNVDYIHDYESIANLVDQIKQQTDIVDDVESWTDPFTNYMNKY-FDPDFPVLPYNQSYFNSKLSQFFFSPRGGKYREQFEFKKPLQCGQEASQ----LMLSKINFVHKVFSGPKEHIPAMNRIKELIAQVNASGRI--FPMSQGYTLWETDEIISEELYRNLGLAVLCVFITTLFLISNVITSFLVLVCVILSLIDVGGFMHFWNLTIDTVSANNLIIAIGLCVDYSAHIAHRFMVEHGTRNQRVRQTLRNIGPAVLNGG--FSTFLAFILLADSKSHV-FSSFFKIFFLVVTFGLFHGLVFLPVILS 988
BLAST of EMLSAG00000004370 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold104_size368486-snap-gene-1.6 (protein:Tk07540 transcript:maker-scaffold104_size368486-snap-gene-1.6-mRNA-1 annotation:"hypothetical protein DAPPUDRAFT_306990") HSP 1 Score: 107.842 bits (268), Expect = 6.729e-24 Identity = 132/543 (24.31%), Postives = 248/543 (45.67%), Query Frame = 0
Query: 375 SNLENFP--LLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYFGITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEW-LKLYYSVGPPVYFVVNSTNMDLA-----------TVKSQNRICGSAGCDPYSFQTAMKLWSTKPDL--TTLATSGQSWIDDYFSWSN---------DCCMVDSQGKICILFSNFMAFHTVLRTSNDFVQAIESTRILSDKFARENNITS--FPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSGKIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEICIGYLTSV 890
+N E F L+ + +A S D N DV +V+ + ++F+YV L F K + +++AG+ V +++++ G+ G +G + + +PFL++ +GID++FV ++ A K +V+ G T++ A+ ++++T AF +G + +PA+ +F L+ G +LI F Q T F+A +SLD RI S + LF E +V + S+ + + + F+ Y L + TVK ++ L + L+ ++ T + DP +PK SY+ ++F+ K Y S G V+ + T++DL ++ +Q+ I F +K +P+L + A + FS S D ++ + I S F H +L + A+ + + RE N + FP+S + +E + + + ++ L +LL L ++ + +T V L++V GF+ + G +L + V L+V G VE+ + + T V
Sbjct: 686 NNQEGFTDGLVSYSHVAR-SFSDIASGNIFTDVNMVVFGFAIVFIYVLLMLGQFHCVKNR-VFVSLAGLVSVFMALVASYGICGTLGFPFSPL-HNFIPFLIMGLGIDDMFV-IMQAWTKFAEHRKDLTKVEKF-GETMKRAGVAITVTSITDFIAFGIGASTLLPALKSFCLFCGVGILITFFLQATWFVAWMSLDQDRIDSGRTLLFTAQKPSSEDEVSHCLSKVD-KNLLQRAFDAY-GQSLSQTHTVKIVILSLTTVFLAFSIWNTTQLRQEFDPVWFLPKDSYLFQWFQLKCKYYPSQGEHVHVFM--TDLDLHGEFHKIESVALSIANQSDIISHVNSWALEFVRYIKKMDLEPNLIVSDFAQFQERLTQFLFSSSGSKYRLLFHYDEELLCGKPSPNISMSIFEFTHRLLDGPGQQIPAMNRIKAI----IREANFSGHVFPFSKGYATWETDEVIMEELVRNLLLALFCILLTTLMLLSNVMAAIQVLTCVVLTLVNVAGFMHVWGKRLEGAMGVALVVIFGTGVELVVIFGTGV 1215
BLAST of EMLSAG00000004370 vs. Tigriopus kingsejongenis genes
Match: snap_masked-scaffold472_size162276-processed-gene-0.4 (protein:Tk12251 transcript:snap_masked-scaffold472_size162276-processed-gene-0.4-mRNA-1 annotation:"hypothetical protein DAPPUDRAFT_306990") HSP 1 Score: 99.3673 bits (246), Expect = 2.230e-21 Identity = 134/614 (21.82%), Postives = 279/614 (45.44%), Query Frame = 0
Query: 392 SIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFR--NKKYFGITLAIAGIFMVLGSILSTTGLFGFIG-VKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLE-GREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYF---------EWLKLYYSVGPPVYF-VVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTT---------------------LATSGQSWIDDYFSWSNDCCMVDSQGKICILFSNFMAFHTVLRTSNDFVQAIESTRILSDKFARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVL-LTMLLICWFLSGKIVIGLYTVTF-----VSSILIHVTGFISMLGIQLNAILAVNLLVACGISVE----ICIGYLT-SVIMGKRSAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLS 959
S D E + DVL+ + + ++F+YV +L ++ F L+ GI + ++ ++ GL +G V + M I+PFL+L +GID++FV+ + L +L + V++ + + ++ A+ ++++T F +G + +PA+ +F ++ +L+ ++ Q T F+A L+ D +RI S + C K P++ ++ + + T F ++ L+K VK +V+V + L+ + +P +P SY+ ++F E ++ ++GP Y + N+ + +K++ I S S+ + K + K DL + +G + ++ N C Q ++ S H + ++ + A+ + + N +S +++ + +Y S +TD +++ V L + ++C F++ ++IG + V L++V GF+ G+ ++ + VNL++A G+ V+ I ++T S +R+ + + + +L G + + ++ SQS++ F FF ++ +VV G HGLI LPV LS
Sbjct: 364 SFNDLSEKVINTDVLLFGVGFGIVFIYVQLSLGKLNLVEQRPF---LSAVGIGCIALTVFTSYGLCSLMGFVFSPM--HNIIPFLLLGIGIDDMFVIC----QSLDNLPPDPSLTVETRVALAMKHAGVAITVTSITDVAVFAIGASTVLPALRSFCVFCAVGILVVYILQATIFVAALAKDSQRIASHRNGFLICYQHKNW----TPQA-WSQKNLLQTAF-YHLGRCLVKPF-VKVAVIVCSLLLLAGGSYGLYLLRQEFNPIWFIPPESYLSQWFAANEKFFPEEGERVTINIGPIDYSEELWKINLLVDKLKNETEIVSSVD----SWFSGFKDYMEKNDLVQDFFETFHVNNTEFYFRLTQFLFSPNGAKYRTNFQFDQNIIC---GQESPSVMLSTIQFTHHLFEGPSEHIPAMNKIK----GIVKSMNFSSRAFAVAN----EYASWETDEIIAQETVRNLLISVVCVFVTTIVLIGNFKACALVLLSVLMTLVNVGGFMHFWGLTIDVVSCVNLVIAVGLCVDYSAHIAHAFMTCSGSKNERTIKAMRDIGPAVLNGG--FSTFLAFALTVTSQSHV-FATFFKIFFLVVVFGLFHGLIFLPVSLS 943
BLAST of EMLSAG00000004370 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold67_size430214-snap-gene-3.36 (protein:Tk00792 transcript:maker-scaffold67_size430214-snap-gene-3.36-mRNA-1 annotation:"patched 1 ") HSP 1 Score: 94.7449 bits (234), Expect = 7.690e-20 Identity = 73/282 (25.89%), Postives = 141/282 (50.00%), Query Frame = 0
Query: 691 TVKSQNRICGSAGC-DPYSFQTAMKLWSTKPDLT------TLATSGQSWIDDYFSWSNDCCMVDSQGKICILFSNFMAFHTVLRTSNDFVQAIESTRILSDKFARENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSGKIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGI----SVEICIGYLTSVIMGKRSAEEVYNDQAGILMSGIHITNLIGVSVLGFSQSNIFFYYFFTVYISIVVIGFVHGLIVLPVLLSFF 961
T+ ++NR+ + G +P F + W T + + + + W+ D S + + SQ I ++ F + + V+ I R + KF + +FP + ++EQYL ++ T+V++ +L + L+ F + +G VT V+ ++ + GF+ ++GI+L+AI AV L+V+ G+ ++ ICIG++T++ R + ++ G I+ +G+ +L FS + F YFF V +++++G +GLI LPV L+F
Sbjct: 762 TLLTRNRLVDAHGMINPSGFYNYLSAWYTNDAMAVSFGQGNIVPTPKLWLHD--SRDYNLKIPKSQ---AIAYAQIPFFLYNVGETEVMVETIRQVREVCQKF-ESLGLPNFPRGLPFTFWEQYLHLRLWTMVALGAILGVIFLVSAFFLMNMWLGAIIVTVVALMIAQLLGFMGIIGIKLSAIPAVILIVSAGMGLQFTIHICIGFITAIGNKNRRILMALSHVFAPVLHGA-ISTFLGIFMLAFSHFDFIFRYFFLVLTAMIILGIFNGLIFLPVFLAFL 1036 HSP 2 Score: 78.9518 bits (193), Expect = 5.778e-15 Identity = 53/191 (27.75%), Postives = 100/191 (52.36%), Query Frame = 0
Query: 397 IESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYFGITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDK 587
+E S V+ + I LM +Y + + + ++ + + + G+ + S+ + GL G + + +IVPFL L +G+D +F+L T + + R ++ +++IG L + ++L+ +L AF L +PA+ F+L A + N +A + F A+LSLDL+RI + K+D+ CC S +
Sbjct: 357 MEKYSEFSVVNLAIGLGLMALYSTVTMVRWSDEVFSQSGIGLCGVLLTALSVAAGLGLCGILDIAFNATTSQIVPFLALGLGVDAMFLLSHTYGETVSNR--RHLQRENIIGDVLRKAGISVLLMSLCNIAAFLAAALIPIPALRAFSLQAAILVGFNSVAMMILFPAVLSLDLRRIFADKVDILCCYSGR 545
BLAST of EMLSAG00000004370 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold171_size289870-snap-gene-1.39 (protein:Tk00433 transcript:maker-scaffold171_size289870-snap-gene-1.39-mRNA-1 annotation:"hypothetical protein DAPPUDRAFT_306990") HSP 1 Score: 79.7221 bits (195), Expect = 1.611e-15 Identity = 59/221 (26.70%), Postives = 115/221 (52.04%), Query Frame = 0
Query: 403 GDVLVVIISYFLMFVYVSFALTDFR--NKKYFGITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKL 621
GD ++ + + ++FVYV L F + F L++ G+ + +IL T GL G+ + ++PFL+L +GID++FV ++ L E + + +IG+T++ A+ ++++T F +G+ + +PA+ +F LY G ++ + Q T F+A L+LDL+R+ + + C K +I+ +S +Y+ F + V ++ K L
Sbjct: 321 GDAFMMPVGFTIVFVYVMIMLGKFNCVETRAF---LSLVGLASIGLTILVTYGLCSAFGLFYGPM-HNVIPFLMLGIGIDDMFV-IMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCY--KHKIEPAEKESEADYEYLSQKVF-RIVGQIITKPL 533
BLAST of EMLSAG00000004370 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold627_size122700-snap-gene-0.37 (protein:Tk10659 transcript:maker-scaffold627_size122700-snap-gene-0.37-mRNA-1 annotation:"hypothetical protein AaeL_AAEL001299") HSP 1 Score: 75.485 bits (184), Expect = 4.855e-14 Identity = 85/343 (24.78%), Postives = 163/343 (47.52%), Query Frame = 0
Query: 359 VEKAIKWEKSFVKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDV--LVVIISYFLMFVYVSFALTDF-RNKKYFGITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREME-VDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSL-----DLKRI---------------KSKKLDLFCCLSDKGEIDVDNPKSRFNYQK-TISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGP 676
+E+ WEK+F+ IE+ LE F + +A + ++++ +E N++ + V I+ ++F ++ ++D+ R+K Y G+ ++ I LGSI + G+ GV I PFL+L +GID+ FV + + RR ME + +G E+ A ++ I++LT +F++G ++ P+V F LY G ++ ++ I F A L+L + R KSK LFC G I+ ++P ++ + + FF S L+ + + ++V+ L +++ N+ GL+ ++ SY +++ Y+ P
Sbjct: 220 MERGKIWEKTFLDTIET-LE-FEHIKVARFSSLTLEIELEENTNSVIPFFSVNIAIMVVFCVITCLMSDWVRSKPYLGLLGLVSAI---LGSI-TAFGVVMLCGVPFIGINLA-APFLMLGIGIDDTFVFLSSWRRS------NPMEPIPKRLGQCYEDSAVSITITSLTDMLSFFVGIITPFPSVKIFCLYTGVAVAFTYMYHIFFFGACLALAGIAEEQNRHALTCFKVLPKSQSLEKSKMYRLFC----SGGINRNDPGNQDDMPTFDMMEFFRGPFSRFLLNQY-ARAMIIVVYLCYLGVSIWGVSNVKEGLERKNLARFDSYSLEFYTLEDTYFRDYP 544 The following BLAST results are available for this feature:
BLAST of EMLSAG00000004370 vs. GO
Analysis Date: 2014-04-02 (Blast vs. GO) Total hits: 25
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BLAST of EMLSAG00000004370 vs. C. finmarchicus
Analysis Date: 2014-05-09 (TblastN vs C. finmarchicus TSA) Total hits: 25
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BLAST of EMLSAG00000004370 vs. L. salmonis peptides
Analysis Date: 2014-05-10 (Blastp vs. self) Total hits: 11
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BLAST of EMLSAG00000004370 vs. SwissProt
Analysis Date: 2017-02-10 (Blastp vs. SwissProt) Total hits: 25
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BLAST of EMLSAG00000004370 vs. Select Arthropod Genomes
Analysis Date: 2017-02-20 (Blastp vs. Selected Arthropods) Total hits: 25
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BLAST of EMLSAG00000004370 vs. nr
Analysis Date: 2017-02-20 (Blastp vs. NR (2/2017)) Total hits: 25
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BLAST of EMLSAG00000004370 vs. Tigriopus kingsejongenis genes
Analysis Date: 2018-04-18 (Blastp vs. Tigriopus kingsejongensis proteins) Total hits: 14
Pagesback to topAlignments
The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Cross References
External references for this gene
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at LSalAtl2s22:157610..161978+ Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>EMLSAG00000004370-687136 ID=EMLSAG00000004370-687136|Name=EMLSAG00000004370|organism=Lepeophtheirus salmonis|type=gene|length=4369bp|location=Sequence derived from alignment at LSalAtl2s22:157610..161978+ (Lepeophtheirus salmonis)back to top Add to Basket
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