EMLSAG00000001950, EMLSAG00000001950-684716 (gene) Lepeophtheirus salmonis
|
Overview
Associated RNAi Experiments
Nothing found Homology
BLAST of EMLSAG00000001950 vs. GO
Match: - (symbol:Npc1a "Niemann-Pick type C-1a" species:7227 "Drosophila melanogaster" [GO:0005765 "lysosomal membrane" evidence=ISS] [GO:0030301 "cholesterol transport" evidence=ISS] [GO:0008158 "hedgehog receptor activity" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0007591 "molting cycle, chitin-based cuticle" evidence=IMP] [GO:0016125 "sterol metabolic process" evidence=IMP] [GO:0045456 "ecdysteroid biosynthetic process" evidence=IMP] [GO:0032374 "regulation of cholesterol transport" evidence=IDA] [GO:0007291 "sperm individualization" evidence=IMP] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 GO:GO:0016021 GO:GO:0007165 GO:GO:0007291 GO:GO:0007591 GO:GO:0032374 GO:GO:0016125 GO:GO:0030301 GO:GO:0008158 GO:GO:0045456 eggNOG:NOG149152 OrthoDB:EOG7QRQT0 TIGRFAMs:TIGR00917 ChiTaRS:NPC1 EMBL:BT009977 ProteinModelPortal:Q7YU59 SMR:Q7YU59 STRING:7227.FBpp0079547 PaxDb:Q7YU59 PRIDE:Q7YU59 FlyBase:FBgn0024320 InParanoid:Q7YU59 Bgee:Q7YU59 Uniprot:Q7YU59) HSP 1 Score: 829.321 bits (2141), Expect = 0.000e+0 Identity = 500/1326 (37.71%), Postives = 714/1326 (53.85%), Query Frame = 0
Query: 21 IWFENCSQSPYLENNADKWLNCAYDGEAKEAP---LLKLERICPHL--DPSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQF--YNTVVESCDVGVNGSEP-CSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNL---FMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENGITLKDICHA-----------------------------------------------------PLEPISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAY--------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAW-TIDDSCCKYRAVDMSVCQSNGESKAKAQSALSFIDKFFENDDFFGGNSVNDFDDYDHEEEEKEESNSSKNGVL--PESMFSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNES--FFQYNVI----ASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
+W+ C+ + + + NC Y+G AKE L L++ C L + CC + Q++++ KN ++ +IL RCP+C+ N ++ C TC P+Q+ F+ V+ + + +E IS+V +++ E++ + Y SC V P A LMCG + C+P +WF ++G +N + PFQI Y+ +H P F N C+ V+ P CSC+DC+ +C E + + + G+D IMA +F+VG ++FL + S + S++ F + DG+D + D P + N S ++ GA E +L FFT WGT+ A P +I S+ + L GI ++ +TTDP++LWASP+S+SR+ER+FFD F PFYR+ Q+I+KA NL ++ G +FGP+F +E FL +L+LQ+ I+ I NG LKDIC+A P ++ G PV P LGGF+P + + + A+A++++ ++ N+ HN + LE AL WEK + YMDIAFTSERSIEDEL +E+ D+ TI VSY+IMF+YI SLG +KR ++SKITLG+GGVIIVL SV +S+G+FG+I +PATLII E+IPFLVLAVG DNIFI+VQT QRD R ET + VGRI+G+V PS+LLTS++ES CFFLG +SDMPAVRAFALYAG+AL+IDFL+Q+TCF+SL +LD R+ +N DI C ++G K + EG++YK F Y PF+MK+ VRA+V++IFF W C S+A+ PRI++GLDQ+L+MP DSFVL YF +++ L++GPPVYFV+ ++ + QN C G C+D+S+ + I L S+ +TYIA PA SWIDDY W SCCKYR C H++ N +KN +L E F KY F+ ++ D D+C K G A+ G YS S H + + E+ F Y+ I A F+ + K + + L+ R +S NG + V+VFPYS+FYVFYEQYLTMWSDT+ S+ +S LSI +VTF+L GFD +++++V+ I MI++NL G+MY+WNISLNAVSLVNLVMAVGISVEFCSH+ +F S ++I RA S
Sbjct: 34 VWYGVCNTNDFSHSQ-----NCPYNGTAKEMATDGLELLKKRCGFLLENSENKFCCDKNQVELLNKNVELAGNILDRCPSCMENLVRHICQFTCSPKQAEFMH--VVATQKNKKGDEY--ISSVDLHISTEYINKTYKSCSQVSVPQTGQLAFDLMCGAYSASRCNPTKWFNFMGDATNPYVPFQITYI-----QHEPKSNSNNFTPLNVTTVPCNQAVSSKLPACSCSDCDLSCPQGPPEPPRPEPFKIVGLDAYFVIMAAVFLVGVLVFL---MGSFLFTQGSSMDDNFQV-DGND-VSDEMPYSENDS------------------------------YFEKLGAHTETFLETFFTKWGTYFASNPGLTLIAGASLVVILGYGINFIEITTDPVKLWASPNSKSRLEREFFDTKFSPFYRLEQIIIKAVNLPQIVHNTSNGP-YTFGPVFDRE-FLTKVLDLQEGIKEINA--NGTQLKDICYAPLSDDGSEIDVSQCVVQSIWGYFGDDRERLDDHDEDNGFNVTYLDALYDCISNPYLCLAPYGGPVDPAIALGGFLPPGDQLTGSTKFELANAIILTFLVKNH-HNKTD------LENALTWEKKFVEFMTNYTKNNMSQYMDIAFTSERSIEDELNRESQSDVLTILVSYLIMFMYIAISLGHVKEFKRVFIDSKITLGIGGVIIVLASVVSSVGVFGYIGLPATLIIVEVIPFLVLAVGVDNIFILVQTHQRDQRKPNETLEQQVGRILGKVGPSILLTSLSESFCFFLGGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRREENRMDICCFIKGKKPD-SITSNEGLLYKFFSSVYVPFLMKKIVRASVMVIFFAWLCFSIAIAPRIDIGLDQELAMPQDSFVLHYFQSLDENLNIGPPVYFVL-KGDLAYTNSSDQNLVCAGQYCNDDSVLTQIYLASRHSNQTYIARPASSWIDDYFDWAAAASSCCKYRKDSGDFCP--------------------------------------HQDTSCLRCNITKNSLLRPEEKEFVKYLPFFLKDNPD-----------------DTCAKA------------GHAAY------------------GGAVRYSNS-----HERLNIEASYFMAYHTILKSSADYFLALESARKISANITQMLQ-GRLMS-------NGVPMASALTVEVFPYSVFYVFYEQYLTMWSDTLQSMGISVLSIFVVTFVLMGFDVHSALVVVITITMIVVNLGGLMYYWNISLNAVSLVNLVMAVGISVEFCSHLVHSFATSKSVSQIDRAADS 1199
BLAST of EMLSAG00000001950 vs. GO
Match: - (symbol:Q8MKD8 "Niemann-Pick C1" species:9685 "Felis catus" [GO:0005635 "nuclear envelope" evidence=ISS] [GO:0005783 "endoplasmic reticulum" evidence=ISS] [GO:0005887 "integral component of plasma membrane" evidence=ISS] [GO:0007041 "lysosomal transport" evidence=ISS] [GO:0008206 "bile acid metabolic process" evidence=ISS] [GO:0042632 "cholesterol homeostasis" evidence=ISS] [GO:0048471 "perinuclear region of cytoplasm" evidence=ISS] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 GO:GO:0005783 GO:GO:0048471 GO:GO:0007165 GO:GO:0005887 GO:GO:0005635 GO:GO:0008206 GO:GO:0042632 GO:GO:0007041 GO:GO:0030301 GO:GO:0008158 HOVERGEN:HBG003913 TIGRFAMs:TIGR00917 EMBL:AF503634 ProteinModelPortal:Q8MKD8 Uniprot:Q8MKD8) HSP 1 Score: 593.578 bits (1529), Expect = 0.000e+0 Identity = 354/983 (36.01%), Postives = 527/983 (53.61%), Query Frame = 0
Query: 21 IWFENCSQSPYLENNADKWLNCAYDGEAKEAPLLK-----LERICP-HLDPSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFE--TQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGVNG-SEPCSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDF-LGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENG--ITLKDICHAPLEPISDGG--IPVQPYYMLGGFIPENE---PFPQNPSYHE--------------------------ASAVVISIMINNYDHNSPNP--------------EEIKKLEKALEWEKAYY----------MDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTI-DDSCCK-YRAVD 934
IW+ C + + DK NC Y G K PL K ++ +CP + +CC +QL ++ N + L RCP+C +N FC +TC P+QS FL T ++ + T + + + + YY+ + F +Y++C+ V PS + AL L+CGK + C+ W Y+ S NG PF I +FS H G++ N + CD V+ + PCSC DC C P + + G+D IM I ++ ++F A + + + + TP+ +N + + + +G +L GA E L F+ WG+FC + P P+I SL+ +G+ ++ VTT+P++LW++PSS++R+E+++FD F PF+R Q+I++A + S+ Y + G FGP L +L+LQ IENI N +TL+DIC APL P + + V Y+ + ++E F YH V +++ YD + N + ++L+KA WEK + + I+FT+ERSIEDEL +E+ GDI T+ +SY IMF+YI+ +LG + R +V+SKI+LG+ G++IVL SVA S+GIF ++ +P TLI+ E+IPFLVLAVG DNIFI+VQT QRD R ET + +GR++GEVAPSM L+S +E+ FFLGA+S MPAV F+L+AGMA+LIDFL+Q+TCF+SL+ LD+ RQ N D++CCVRGS+ E +++LFKH Y+P ++K+W+R V+ IF G S+AV ++E+GLDQ LSMPDDS+V+ YF + KYL GPPVYFV++ + SL G QN CGG GC+++SL I ++ T I SWIDDY W SCC+ Y + D
Sbjct: 26 IWYGECGIA-----SGDKRYNCKYSGPPK--PLPKDGYDLVQELCPGFFFDNVSLCCDVQQLQTLKDNLQLPLQFLSRCPSCFYNLVNLFCELTCSPRQSQFLN-VTATEDYVDPVTNQTKTNVKELQYYIGESFANAMYNACRDVEAPSSNDKALGLLCGKDAEA-CNATNWIEYMFSKDNGQAPFTITPIFSDLPTH-----GMEPMNNATKGCDESVDEVTGPCSCQDCSIVCGPKPQPPPPPVPWRILGLDAMYVIMWITYMAFLLVFFGAFFALWCYRKRY----------FVSEYTPI------------DSNIAFSVNANDRGEASCCDAL------GAAFEGCLRRLFSQWGSFCVRNPGPIIFFSLAFIAACSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDTHFGPFFRTEQLIIQAPHTSAHTYQPYPSGSDVPFGPPL-DLAILHQVLDLQTAIENITASYNNETVTLQDICVAPLSPYNKNCTILSVLNYFQNSHSMLDHEIGDDFFVYADYHTHLLYCVRAPASLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTERLQKAHVWEKEFINFVKNYKNPNLTISFTTERSIEDELNRESNGDIFTVIISYAIMFLYISIALGHIKSCSRLLVDSKISLGIAGILIVLSSVACSLGIFSYVGIPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLHGETLDQQLGRVLGEVAPSMFLSSFSEAVAFFLGALSKMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNRLDVLCCVRGSEDGTSVQASESCLFRLFKHSYSPLLLKDWMRPIVIAIFVGVLSFSVAVLNKVEIGLDQSLSMPDDSYVMDYFKSL-KYLHAGPPVYFVLEEGHDYTSLKG-QNMVCGGMGCNNDSLVQQIFNAAQLDSYTRIGFAPSSWIDDYFDWVKPQSSCCRVYNSTD 963 HSP 2 Score: 197.978 bits (502), Expect = 6.745e-50 Identity = 105/230 (45.65%), Postives = 150/230 (65.22%), Query Frame = 0
Query: 1031 SCIKC-PNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
+CI+C P + + +RP F R++ FL DNP +C K GHAAYS +V + + V A+ FMT+HT+L+T D+ +A+R A ++S I ++ + +VFPYS+FYVFYEQYLT+ DTI +L VS +I +VT IL G D +++I+ + IAMIL+N+ G+M+ W ISLNAVSLVNLVM+ GISVEFCSHI +AFT SM+ ++ RA+ +
Sbjct: 974 ACIRCRPLTQEG--KQRPQGGDFMRFLPMFLSDNPNPKCGKGGHAAYSSAVNILGN---------DTGVGATYFMTYHTVLQTSADFTDAMRKANLIASNITKTMG----LEGSNYRVFPYSVFYVFYEQYLTIIDDTIFNLSVSLGAIFLVTVILLGCDLWSAVIMCITIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRAQRAEEA 1188
BLAST of EMLSAG00000001950 vs. GO
Match: - (symbol:Q8MI49 "Mutant Niemann-Pick C1" species:9685 "Felis catus" [GO:0005635 "nuclear envelope" evidence=ISS] [GO:0005783 "endoplasmic reticulum" evidence=ISS] [GO:0005887 "integral component of plasma membrane" evidence=ISS] [GO:0007041 "lysosomal transport" evidence=ISS] [GO:0008206 "bile acid metabolic process" evidence=ISS] [GO:0042632 "cholesterol homeostasis" evidence=ISS] [GO:0048471 "perinuclear region of cytoplasm" evidence=ISS] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 GO:GO:0005783 GO:GO:0048471 GO:GO:0007165 GO:GO:0005887 GO:GO:0005635 GO:GO:0008206 GO:GO:0042632 GO:GO:0007041 GO:GO:0030301 GO:GO:0008158 eggNOG:NOG149152 HOVERGEN:HBG003913 TIGRFAMs:TIGR00917 EMBL:AF503633 ProteinModelPortal:Q8MI49 STRING:9685.ENSFCAP00000000483 Uniprot:Q8MI49) HSP 1 Score: 591.267 bits (1523), Expect = 0.000e+0 Identity = 353/983 (35.91%), Postives = 525/983 (53.41%), Query Frame = 0
Query: 21 IWFENCSQSPYLENNADKWLNCAYDGEAKEAPLLK-----LERICP-HLDPSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFE--TQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGVNG-SEPCSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDF-LGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENG--ITLKDICHAPLEPISDGG--IPVQPYYMLGGFIPENE---PFPQNPSYHE--------------------------ASAVVISIMINNYDHNSPNP--------------EEIKKLEKALEWEKAYY----------MDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTI--DDSCCKYRAVD 934
IW+ C + + DK NC Y G K PL K ++ +CP + +CC +QL ++ N + L RCP+C +N FC +TC P+QS FL T ++ + T + + + + YY+ + F +Y++C+ V PS + AL L+CGK + C+ W Y+ S NG PF I +FS H G++ N + CD V+ + PCSC DC C P + + G+D IM I ++ ++F A + + + + TP+ +N + + + +G +L GA E L F+ WG+FC + P P+I SL+ +G+ ++ VTT+P++LW++PSS++R+E+++FD F PF+R Q+I++A + S+ Y + G FGP L +L+LQ IENI N +TL+DIC APL P + + V Y+ + ++E F YH V +++ YD + N + ++L+KA WEK + + I+FT+ERSIEDEL +E+ GDI T+ +SY IMF+YI+ +LG + R +V+SKI+LG+ G++IVL SVA S+GIF ++ +P TLI+ E+IPFLVLAVG DNIFI+VQT QRD R ET + +GR++GEVAPSM L+S +E+ FFLGA+S MPAV F+L+AGMA+LIDFL+Q+TCF+SL+ LD+ RQ N D++CCVRGS+ E +++LFKH Y+P ++K+W+R V+ IF G S+AV ++E+GLDQ LSMPDDS+V+ YF + KYL GPPVYFV++ + SL G QN CGG GC+++SL I ++ T I SWIDDY W SC Y + D
Sbjct: 26 IWYGECGIA-----SGDKRYNCKYSGPPK--PLPKDGYDLVQELCPGFFFDNVSLCCDVQQLQTLKDNLQLPLQFLSRCPSCFYNLVNLFCELTCSPRQSQFLN-VTATEDYVDPVTNQTKTNVKELQYYIGESFANAMYNACRDVEAPSSNDKALGLLCGKDAEA-CNATNWIEYMFSKDNGQAPFTITPIFSDLPTH-----GMEPMNNATKGCDESVDEVTGPCSCQDCSIVCGPKPQPPPPPVPWRILGLDAMYVIMWITYMAFLLVFFGAFFALWCYRKRY----------FVSEYTPI------------DSNIAFSVNANDRGEASCCDAL------GAAFEGCLRRLFSQWGSFCVRNPGPIIFFSLAFIAACSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDTHFGPFFRTEQLIIQAPHTSAHTYQPYPSGSDVPFGPPL-DLAILHQVLDLQTAIENITASYNNETVTLQDICVAPLSPYNKNCTILSVLNYFQNSHSMLDHEIGDDFFVYADYHTHLLYCVRAPASLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTERLQKAHVWEKEFINFVKNYKNPNLTISFTTERSIEDELNRESNGDIFTVIISYAIMFLYISIALGHIKSCSRLLVDSKISLGIAGILIVLSSVACSLGIFSYVGIPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLHGETLDQQLGRVLGEVAPSMFLSSFSEAVAFFLGALSKMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNRLDVLCCVRGSEDGTSVQASESCLFRLFKHSYSPLLLKDWMRPIVIAIFVGVLSFSVAVLNKVEIGLDQSLSMPDDSYVMDYFKSL-KYLHAGPPVYFVLEEGHDYTSLKG-QNMVCGGMGCNNDSLVQQIFNAAQLDSYTRIGFAPSSWIDDYFDWVKPQSSSCRVYNSTD 963 HSP 2 Score: 197.978 bits (502), Expect = 6.687e-50 Identity = 105/228 (46.05%), Postives = 149/228 (65.35%), Query Frame = 0
Query: 1031 SCIKC-PNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAK 1257
+CI+C P + + +RP F R++ FL DNP +C K GHAAYS +V + + V A+ FMT+HT+L+T D+ +A+R A ++S I ++ + +VFPYS+FYVFYEQYLT+ DTI +L VS +I +VT IL G D +++I+ + IAMIL+N+ G+M+ W ISLNAVSLVNLVM+ GISVEFCSHI +AFT SM+ ++ RA+
Sbjct: 974 ACIRCRPLTQEG--KQRPQGGDFMRFLPMFLSDNPNPKCGKGGHAAYSSAVNILGN---------DTGVGATYFMTYHTVLQTSADFTDAMRKANLIASNITKTMG----LEGSNYRVFPYSVFYVFYEQYLTIIDDTIFNLSVSLGAIFLVTVILLGCDLWSAVIMCITIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRAQRAE 1186
BLAST of EMLSAG00000001950 vs. GO
Match: - (symbol:NPC1 "Niemann-Pick type C1 disease protein" species:9685 "Felis catus" [GO:0005635 "nuclear envelope" evidence=ISS] [GO:0005783 "endoplasmic reticulum" evidence=ISS] [GO:0005887 "integral component of plasma membrane" evidence=ISS] [GO:0007041 "lysosomal transport" evidence=ISS] [GO:0008206 "bile acid metabolic process" evidence=ISS] [GO:0042632 "cholesterol homeostasis" evidence=ISS] [GO:0048471 "perinuclear region of cytoplasm" evidence=ISS] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 GO:GO:0005783 GO:GO:0048471 GO:GO:0007165 GO:GO:0005887 GO:GO:0005635 GO:GO:0008206 GO:GO:0042632 GO:GO:0007041 GO:GO:0030301 GO:GO:0008158 KO:K12385 CTD:4864 HOVERGEN:HBG003913 TIGRFAMs:TIGR00917 EMBL:AF258783 RefSeq:NP_001009829.2 ProteinModelPortal:Q9N0Q0 GeneID:493693 KEGG:fca:493693 Uniprot:Q9N0Q0) HSP 1 Score: 590.882 bits (1522), Expect = 0.000e+0 Identity = 353/983 (35.91%), Postives = 526/983 (53.51%), Query Frame = 0
Query: 21 IWFENCSQSPYLENNADKWLNCAYDGEAKEAPLLK-----LERICP-HLDPSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFE--TQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGVNG-SEPCSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDF-LGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENG--ITLKDICHAPLEPISDGG--IPVQPYYMLGGFIPENE---PFPQNPSYHE--------------------------ASAVVISIMINNYDHNSPNP--------------EEIKKLEKALEWEKAYY----------MDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTI-DDSCCK-YRAVD 934
IW+ C + + DK NC Y G K PL K ++ +CP + +CC +QL ++ N + L RCP+C +N FC +TC P+QS FL T ++ + T + + + + YY+ + F +Y++C+ V PS + AL L+CGK + C+ W Y+ S NG PF I +FS H G++ N + CD V+ + PCSC DC C P + + G+D IM I ++ ++F A + + + + TP+ +N + + + +G +L GA E L F+ WG+FC + P P+I SL+ +G+ ++ VTT+P++LW++PSS++R+E+++FD F PF+R Q+I++A + S+ Y + G FGP L +L+LQ IENI N +TL+DIC APL P + + V Y+ + ++E F YH V +++ YD + N + ++L+KA WEK + + I+FT+ERSIEDEL +E+ GDI T+ +SY IMF+YI+ +LG + R +V+SKI+LG+ G++IVL S A S+GIF ++ +P TLI+ E+IPFLVLAVG DNIFI+VQT QRD R ET + +GR++GEVAPSM L+S +E+ FFLGA+S MPAV F+L+AGMA+LIDFL+Q+TCF+SL+ LD+ RQ N D++CCVRGS+ E +++LFKH Y+P ++K+W+R V+ IF G S+AV ++E+GLDQ LSMPDDS+V+ YF + KYL GPPVYFV++ + SL G QN CGG GC+++SL I ++ T I SWIDDY W SCC+ Y + D
Sbjct: 26 IWYGECGIA-----SGDKRYNCKYSGPPK--PLPKDGYDLVQELCPGFFFDNVSLCCDVQQLQTLKDNLQLPLQFLSRCPSCFYNLVNLFCELTCSPRQSQFLN-VTATEDYVDPVTNQTKTNVKELQYYIGESFANAMYNACRDVEAPSSNDKALGLLCGKDAEA-CNATNWIEYMFSKDNGQAPFTITPIFSDLPTH-----GMEPMNNATKGCDESVDEVTGPCSCQDCSIVCGPKPQPPPPPVPWRILGLDAMYVIMWITYMAFLLVFFGAFFALWCYRKRY----------FVSEYTPI------------DSNIAFSVNANDRGEASCCDAL------GAAFEGCLRRLFSQWGSFCVRNPGPIIFFSLAFIAACSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDTHFGPFFRTEQLIIQAPHTSAHTYQPYPSGSDVPFGPPL-DLAILHQVLDLQTAIENITASYNNETVTLQDICVAPLSPYNKNCTILSVLNYFQNSHSMLDHEIGDDFFVYADYHTHLLYCVRAPASLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTERLQKAHVWEKEFINFVKNYKNPNLTISFTTERSIEDELNRESNGDIFTVIISYAIMFLYISIALGHIKSCSRLLVDSKISLGIAGILIVLSSKACSLGIFSYVGIPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLHGETLDQQLGRVLGEVAPSMFLSSFSEAVAFFLGALSKMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNRLDVLCCVRGSEDGTSVQASESCLFRLFKHSYSPLLLKDWMRPIVIAIFVGVLSFSVAVLNKVEIGLDQSLSMPDDSYVMDYFKSL-KYLHAGPPVYFVLEEGHDYTSLKG-QNMVCGGMGCNNDSLVQQIFNAAQLDSYTRIGFAPSSWIDDYFDWVKPQSSCCRVYNSTD 963 HSP 2 Score: 197.978 bits (502), Expect = 6.573e-50 Identity = 105/230 (45.65%), Postives = 150/230 (65.22%), Query Frame = 0
Query: 1031 SCIKC-PNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
+CI+C P + + +RP F R++ FL DNP +C K GHAAYS +V + + V A+ FMT+HT+L+T D+ +A+R A ++S I ++ + +VFPYS+FYVFYEQYLT+ DTI +L VS +I +VT IL G D +++I+ + IAMIL+N+ G+M+ W ISLNAVSLVNLVM+ GISVEFCSHI +AFT SM+ ++ RA+ +
Sbjct: 974 ACIRCRPLTQEG--KQRPQGGDFMRFLPMFLSDNPNPKCGKGGHAAYSSAVNILGN---------DTGVGATYFMTYHTVLQTSADFTDAMRKANLIASNITKTMG----LEGSNYRVFPYSVFYVFYEQYLTIIDDTIFNLSVSLGAIFLVTVILLGCDLWSAVIMCITIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRAQRAEEA 1188
BLAST of EMLSAG00000001950 vs. GO
Match: - (symbol:NPC1 "Niemann-Pick type C1 protein" species:10029 "Cricetulus griseus" [GO:0005635 "nuclear envelope" evidence=ISS] [GO:0005783 "endoplasmic reticulum" evidence=ISS] [GO:0005887 "integral component of plasma membrane" evidence=ISS] [GO:0007041 "lysosomal transport" evidence=ISS] [GO:0008206 "bile acid metabolic process" evidence=ISS] [GO:0042632 "cholesterol homeostasis" evidence=ISS] [GO:0048471 "perinuclear region of cytoplasm" evidence=ISS] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 GO:GO:0005783 GO:GO:0048471 GO:GO:0007165 GO:GO:0005887 GO:GO:0005635 GO:GO:0008206 GO:GO:0042632 GO:GO:0007041 GO:GO:0030301 GO:GO:0008158 KO:K12385 CTD:4864 HOVERGEN:HBG003913 TIGRFAMs:TIGR00917 EMBL:AF182744 RefSeq:NP_001233616.1 ProteinModelPortal:Q9JLG3 GeneID:100689424 KEGG:cge:100689424 Uniprot:Q9JLG3) HSP 1 Score: 580.867 bits (1496), Expect = 0.000e+0 Identity = 351/989 (35.49%), Postives = 524/989 (52.98%), Query Frame = 0
Query: 21 IWFENCSQSPYLENNADKWLNCAYDGEAKEAPLLK-----LERICP-HLDPSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFE--TQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGVNG-SEPCSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDF-LGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENG--ITLKDICHAPLEPISDGG--IPVQPYYMLGGFIPENE---PFPQNPSYHE--------------------------ASAVVISIMINNYDHNSPNP--------------EEIKKLEKALEWEKAYY----------MDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTI-DDSCCKYRAVDMSVCQSN 941
+W+ C + DK NC Y G K PL K L+ +CP + +CC +QL ++ N + L RCP+C +N FC +TC P QS FL T ++ + TQE + + + YY+ F +Y++C+ V P+ + AL ++CGK C+ W Y+ + +NG PF I +FS PI G++ + C+ V+ + PCSC DC C P + + G+D IM + ++ IF ++A + + F + + TP+ N + S TS KG L GA + L FT WG FC + P VI SL +G+ ++ VTT+P+ELW++P SR+R+E+++FDK F PF+R+ Q+I++A N S Y+ + G SFGP +K E L +L+LQ IE+I T N +TL+DIC APL P + I V Y+ + +++ F YH V +++ YD + N + +KL++A WEK + + I+F +ERSIEDEL +E+ D+ TIA+SY IMF+YI+ +LG + R +V+SKI+LG+ G++IVL SVA S+G+F ++ +P TLI+ E+IPFLVLAVG DNIFI+VQT QRD R ET + +GRI+GEVAP+M L+S +E++ FF GA+S MPAV F+L+AG+A+LIDFL+Q+TCF+SL+ LD+ RQ N DI+CCV G+ E +++ FK+ +APF++K+W+R V+ +F G S+AV ++E+GLDQ LSMP+DS+V+ YF + +YL GPPVYFV++ + D + QN CGG GC ++SL I ++ T I SWIDDY W SCC+ C ++
Sbjct: 26 VWYGECGIA-----FGDKKYNCKYSGPPK--PLPKDGNDLLQELCPGFFFGNVSLCCDVQQLQTLKSNLQLPMQFLSRCPSCFYNLMTLFCELTCSPHQSQFLN-VTATEDYVDPKTQENKTNVKELEYYIGQSFANEMYNACRDVEAPASNEKALGILCGK-DASACNATNWIEYMFNKNNGQAPFTITPIFS----DLPI-LGMEPMRNATKGCNESVDEVTGPCSCQDCSIVCGPKPQPPPTPVPWRILGLDAMYVIMWVTYMAFLFIFFGGLLA--VWCHRRRYF--------VSEYTPIDSNIAFSSNTSD------------KGEASCCDPL------GAAFDDCLRRMFTKWGAFCVRNPTCVIFFSLVFITACSSGLVFVRVTTNPVELWSAPHSRARLEKEYFDKHFGPFFRMEQLIIQAPNTSEHIYEPYPSGSDVSFGPPLNK-EILHQVLDLQIAIESITTSYNNKTVTLQDICVAPLSPYNKNCTIISVLNYFQNSHSVLDHQVGDDFYVYADYHTHFLYCVRAPTSLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVSNYYNDTEKLQRAQAWEKEFIDFVKSYKNPNLTISFIAERSIEDELNRESNSDVFTIAISYAIMFLYISLALGHIKSCSRLLVDSKISLGIAGILIVLSSVACSLGVFSYMGMPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFGALSSMPAVHTFSLFAGLAVLIDFLLQITCFVSLLGLDIKRQEKNRLDILCCVGGTDNGRGIQASESYLFRFFKNSFAPFLLKDWLRPIVIAVFVGVLSFSIAVMNKVEIGLDQSLSMPNDSYVIDYFKSLGQYLHSGPPVYFVLEEGH-DYTTHKGQNMVCGGMGCDNDSLVQQIFNAAELDNYTRIGFAPSSWIDDYFDWVAPQSSCCRLYNATHQFCNAS 970 HSP 2 Score: 199.904 bits (507), Expect = 1.633e-50 Identity = 104/228 (45.61%), Postives = 155/228 (67.98%), Query Frame = 0
Query: 1031 SCIKC-PNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAK 1257
+CI+C P + + +RP K F +++ FL DNP +C K GHAAYS +V + ++++ V A+ FMT+HT+LKT DY +A++ A+ ++ I ++N K +VFPYS+FYVFYEQYLT+ DTI +L VS SI +VT ++ G + +++I+ + IAMIL+N+ G+M+ W+ISLNAVSLVNLVM+ GISVEFCSHI +AFT S + +++ RA+
Sbjct: 975 TCIRCRPLTPEG--KQRPQGKEFMKFLPMFLSDNPNPKCGKGGHAAYSSAVNIIG-----DDTY----VGATYFMTYHTVLKTSADYIDAMKKAQLVARNITETMN----SKGSNYRVFPYSVFYVFYEQYLTIIDDTIFNLSVSLGSIFLVTLVVLGCELWSAVIMCITIAMILVNMFGVMWLWDISLNAVSLVNLVMSCGISVEFCSHITRAFTMSTKGSRVSRAE 1187
BLAST of EMLSAG00000001950 vs. GO
Match: - (symbol:Npc1 "RCG41239" species:10116 "Rattus norvegicus" [GO:0005576 "extracellular region" evidence=IEA] [GO:0005635 "nuclear envelope" evidence=IEA] [GO:0005768 "endosome" evidence=IEA] [GO:0005783 "endoplasmic reticulum" evidence=IEA] [GO:0005794 "Golgi apparatus" evidence=IEA] [GO:0005887 "integral component of plasma membrane" evidence=IEA] [GO:0006486 "protein glycosylation" evidence=IEA] [GO:0006897 "endocytosis" evidence=IEA] [GO:0006914 "autophagy" evidence=IEA] [GO:0007628 "adult walking behavior" evidence=IEA] [GO:0008158 "hedgehog receptor activity" evidence=IEA] [GO:0015485 "cholesterol binding" evidence=IEA] [GO:0016242 "negative regulation of macroautophagy" evidence=IEA] [GO:0031982 "vesicle" evidence=IEA] [GO:0033344 "cholesterol efflux" evidence=IEA] [GO:0042493 "response to drug" evidence=IEA] [GO:0045121 "membrane raft" evidence=IEA] [GO:0048471 "perinuclear region of cytoplasm" evidence=IEA] [GO:0071383 "cellular response to steroid hormone stimulus" evidence=IEA] [GO:0071404 "cellular response to low-density lipoprotein particle stimulus" evidence=IEA] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 RGD:628693 GO:GO:0005783 GO:GO:0005794 GO:GO:0046686 GO:GO:0048471 GO:GO:0007165 GO:GO:0005576 GO:GO:0005887 GO:GO:0005635 GO:GO:0006914 GO:GO:0045121 GO:GO:0042493 GO:GO:0005768 GO:GO:0006486 GO:GO:0006897 GO:GO:0005764 GO:GO:0015485 GO:GO:0033344 GO:GO:0007628 GO:GO:0031982 GO:GO:0060548 GO:GO:0008158 GO:GO:0071404 GO:GO:0071383 GO:GO:0016242 GeneTree:ENSGT00680000099777 KO:K12385 OrthoDB:EOG7QRQT0 CTD:4864 TreeFam:TF300416 TIGRFAMs:TIGR00917 OMA:ITRAFTM EMBL:CH474073 EMBL:AABR06093698 EMBL:AABR06093699 EMBL:AABR06093700 RefSeq:NP_705888.2 UniGene:Rn.115253 Ensembl:ENSRNOT00000016167 GeneID:266732 KEGG:rno:266732 NextBio:624576 PRO:PR:G3V7K5 Uniprot:G3V7K5) HSP 1 Score: 579.326 bits (1492), Expect = 0.000e+0 Identity = 347/989 (35.09%), Postives = 522/989 (52.78%), Query Frame = 0
Query: 21 IWFENCSQSPYLENNADKWLNCAYDGEAKEAPLLK-----LERICPHLD-PSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHF--ETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGVNG-SEPCSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDF-LGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENG--ITLKDICHAPLEPISDGG--IPVQPYYMLGGFIPENE---PFPQNPSYHE--------------------------ASAVVISIMINNYDHNSPNP--------------EEIKKLEKALEWEKAYY----------MDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAW-TIDDSCCKYRAVDMSVCQSN 941
+W+ C + DK NC Y G K PL K ++ +CP L + +CC +QL ++ N + L RCP+C +N FC +TC P QS FL T ++F ET+E + + + YYV F +Y++C+ V PS + AL L+CG+ + C+ W Y+ + NG PF I VFS + G++ + C+ V+ + PCSC DC + C P + + G+D IM + ++ ++F ++A + + F + + TP+ N + S +S KG L G + L FT WG FC + P +I SL +G+ ++ VTT+P+ELW++P S++R+E+++FDK F PF+R Q+I++A N S Y+ + G FGP +K E L +L+LQ IE+I N +TL+DIC APL P + + V Y+ + +N+ F YH V +++ YD + N + +KL++A WEK + + I+FT+ERSIEDEL +E+ D+ T+ +SY +MF+YI+ +LG +W R +V+SKI+LG+ G++IVL SV S+GIF +I +P TLI+ E+IPFLVLAVG DNIFI+VQT QRD R ET + +GRI+GEVAP+M L+S +E++ FF GA+S MPAV F+L+AGMA+LIDFL+Q+TCF+S + LD+ RQ N DI+CCVRG E +++ FK+ +APF++ +W+R V+ +F G S+AV ++E+GLDQ LSMP+DS+V+ YF + +YL GPPVYFV++ S G QN CGG GC ++SL I ++ T + SWIDDY W + SCC+ V C ++
Sbjct: 27 VWYGECGVA-----FGDKRYNCEYSGPPK--PLPKDGYDLVQELCPGLFFGNVSLCCDVQQLQTLKSNLQLPLQFLSRCPSCFYNLMTLFCELTCSPHQSQFLN-VTATEDYFDPETRENKTNVKELEYYVGRSFANAMYNACRDVEAPSSNEKALGLLCGR-DARACNATNWIEYMFNKDNGQAPFTIIPVFSDLSVL-----GMEPMRNATKGCNESVDEVTGPCSCQDCSAVCGPKPQPPPPPVPWRILGLDAMYVIMWVAYMAFLVLFFGGLLA--VWCHRRRYF--------VSEYTPIDSNIAFSSNSSD------------KGEASCCDPL------GVAFDDCLRRMFTKWGAFCVRNPTCIIFFSLVFIAACSSGLVFVQVTTNPVELWSAPHSQARLEKEYFDKHFGPFFRTEQLIIQAPNSSVHIYEPYPSGADVPFGPPLNK-EILHQVLDLQIAIESITASYNNETVTLQDICVAPLSPYNKNCTIMSVLNYFQNSHAVLDNQVGDDFFVYADYHTHFLYCVRAPASLNDTSLLHGPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTEKLQRAWAWEKEFINFVKNYKNPNLTISFTAERSIEDELNRESNSDVFTVLISYAVMFLYISLALGHIQSWNRVLVDSKISLGIAGILIVLSSVTCSLGIFSYIGMPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFGALSSMPAVHTFSLFAGMAVLIDFLLQITCFVSFLGLDIKRQEKNRLDILCCVRGPDDGQESQASESYLFRFFKNAFAPFLLTDWLRPVVMAVFVGILSFSIAVVNKVEIGLDQSLSMPNDSYVIDYFKSLGQYLHSGPPVYFVLEEGYNYSSRRG-QNMVCGGMGCDNDSLVQQIFNAAELDTYTRVGFAPSSWIDDYFDWVSPQSSCCRLYNVTHQFCNAS 971 HSP 2 Score: 197.593 bits (501), Expect = 7.967e-50 Identity = 104/230 (45.22%), Postives = 153/230 (66.52%), Query Frame = 0
Query: 1031 SCIKC-PNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
+C++C P + + +RP K F +++ FL DNP +C K GHAAYS +V + ++++ + A+ FMT+HTILKT DY +AL+ AR ++S I ++ +D +VFPYS+FYVFYEQYLT+ D I +L VS SI +VT + G + +++I+ + IAMIL+N+ G+M+ W ISLNAVSLVNLVM GISVEFCSHI +AFT S + +++ RA+ +
Sbjct: 976 TCVRCRPLTPEG--KQRPQGKEFMKFLPMFLSDNPNPKCGKGGHAAYSSAVNIMG-----DDTY----IGATYFMTYHTILKTSADYIDALKKARLIASNITETMRSKGSD----YRVFPYSVFYVFYEQYLTIIDDAIFNLSVSLGSIFLVTLVALGCELWSAVIMCLTIAMILVNMFGVMWLWGISLNAVSLVNLVMTCGISVEFCSHITRAFTMSTKGSRVSRAEEA 1190
BLAST of EMLSAG00000001950 vs. GO
Match: - (symbol:Npc1 "Niemann-Pick disease, type C1" species:10116 "Rattus norvegicus" [GO:0005576 "extracellular region" evidence=IEA;ISO] [GO:0005635 "nuclear envelope" evidence=IEA;ISO] [GO:0005764 "lysosome" evidence=ISO] [GO:0005765 "lysosomal membrane" evidence=IEA;ISO] [GO:0005768 "endosome" evidence=IEA;ISO] [GO:0005783 "endoplasmic reticulum" evidence=IEA;ISO] [GO:0005794 "Golgi apparatus" evidence=IEA;ISO] [GO:0005886 "plasma membrane" evidence=ISO] [GO:0005887 "integral component of plasma membrane" evidence=IEA;ISO] [GO:0006486 "protein glycosylation" evidence=IEA;ISO] [GO:0006897 "endocytosis" evidence=IEA;ISO] [GO:0006914 "autophagy" evidence=IEA;ISO] [GO:0007628 "adult walking behavior" evidence=IEA;ISO] [GO:0008158 "hedgehog receptor activity" evidence=IEA] [GO:0015485 "cholesterol binding" evidence=IEA;ISO] [GO:0016020 "membrane" evidence=ISO] [GO:0016242 "negative regulation of macroautophagy" evidence=IEA;ISO] [GO:0030301 "cholesterol transport" evidence=ISO] [GO:0031982 "vesicle" evidence=IEA;ISO] [GO:0033344 "cholesterol efflux" evidence=IEA;ISO] [GO:0042493 "response to drug" evidence=IEA;ISO] [GO:0042632 "cholesterol homeostasis" evidence=ISO] [GO:0045121 "membrane raft" evidence=IEA;ISO] [GO:0046686 "response to cadmium ion" evidence=IDA] [GO:0048471 "perinuclear region of cytoplasm" evidence=IEA;ISO] [GO:0060548 "negative regulation of cell death" evidence=IMP] [GO:0070062 "extracellular vesicular exosome" evidence=ISO] [GO:0071383 "cellular response to steroid hormone stimulus" evidence=IEA;ISO] [GO:0071404 "cellular response to low-density lipoprotein particle stimulus" evidence=IEA;ISO] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 RGD:628693 GO:GO:0005783 GO:GO:0005794 GO:GO:0046686 GO:GO:0048471 GO:GO:0007165 GO:GO:0005576 GO:GO:0005887 GO:GO:0005635 GO:GO:0006914 GO:GO:0045121 GO:GO:0042493 GO:GO:0005768 GO:GO:0006486 GO:GO:0006897 GO:GO:0005764 GO:GO:0015485 GO:GO:0033344 GO:GO:0007628 GO:GO:0031982 GO:GO:0060548 GO:GO:0008158 GO:GO:0071404 GO:GO:0071383 GO:GO:0016242 GeneTree:ENSGT00680000099777 KO:K12385 OrthoDB:EOG7QRQT0 CTD:4864 TreeFam:TF300416 TIGRFAMs:TIGR00917 OMA:ITRAFTM EMBL:CH474073 EMBL:AABR06093698 EMBL:AABR06093699 EMBL:AABR06093700 RefSeq:NP_705888.2 UniGene:Rn.115253 Ensembl:ENSRNOT00000016167 GeneID:266732 KEGG:rno:266732 NextBio:624576 PRO:PR:G3V7K5 Uniprot:G3V7K5) HSP 1 Score: 579.326 bits (1492), Expect = 0.000e+0 Identity = 347/989 (35.09%), Postives = 522/989 (52.78%), Query Frame = 0
Query: 21 IWFENCSQSPYLENNADKWLNCAYDGEAKEAPLLK-----LERICPHLD-PSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHF--ETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGVNG-SEPCSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDF-LGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENG--ITLKDICHAPLEPISDGG--IPVQPYYMLGGFIPENE---PFPQNPSYHE--------------------------ASAVVISIMINNYDHNSPNP--------------EEIKKLEKALEWEKAYY----------MDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAW-TIDDSCCKYRAVDMSVCQSN 941
+W+ C + DK NC Y G K PL K ++ +CP L + +CC +QL ++ N + L RCP+C +N FC +TC P QS FL T ++F ET+E + + + YYV F +Y++C+ V PS + AL L+CG+ + C+ W Y+ + NG PF I VFS + G++ + C+ V+ + PCSC DC + C P + + G+D IM + ++ ++F ++A + + F + + TP+ N + S +S KG L G + L FT WG FC + P +I SL +G+ ++ VTT+P+ELW++P S++R+E+++FDK F PF+R Q+I++A N S Y+ + G FGP +K E L +L+LQ IE+I N +TL+DIC APL P + + V Y+ + +N+ F YH V +++ YD + N + +KL++A WEK + + I+FT+ERSIEDEL +E+ D+ T+ +SY +MF+YI+ +LG +W R +V+SKI+LG+ G++IVL SV S+GIF +I +P TLI+ E+IPFLVLAVG DNIFI+VQT QRD R ET + +GRI+GEVAP+M L+S +E++ FF GA+S MPAV F+L+AGMA+LIDFL+Q+TCF+S + LD+ RQ N DI+CCVRG E +++ FK+ +APF++ +W+R V+ +F G S+AV ++E+GLDQ LSMP+DS+V+ YF + +YL GPPVYFV++ S G QN CGG GC ++SL I ++ T + SWIDDY W + SCC+ V C ++
Sbjct: 27 VWYGECGVA-----FGDKRYNCEYSGPPK--PLPKDGYDLVQELCPGLFFGNVSLCCDVQQLQTLKSNLQLPLQFLSRCPSCFYNLMTLFCELTCSPHQSQFLN-VTATEDYFDPETRENKTNVKELEYYVGRSFANAMYNACRDVEAPSSNEKALGLLCGR-DARACNATNWIEYMFNKDNGQAPFTIIPVFSDLSVL-----GMEPMRNATKGCNESVDEVTGPCSCQDCSAVCGPKPQPPPPPVPWRILGLDAMYVIMWVAYMAFLVLFFGGLLA--VWCHRRRYF--------VSEYTPIDSNIAFSSNSSD------------KGEASCCDPL------GVAFDDCLRRMFTKWGAFCVRNPTCIIFFSLVFIAACSSGLVFVQVTTNPVELWSAPHSQARLEKEYFDKHFGPFFRTEQLIIQAPNSSVHIYEPYPSGADVPFGPPLNK-EILHQVLDLQIAIESITASYNNETVTLQDICVAPLSPYNKNCTIMSVLNYFQNSHAVLDNQVGDDFFVYADYHTHFLYCVRAPASLNDTSLLHGPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTEKLQRAWAWEKEFINFVKNYKNPNLTISFTAERSIEDELNRESNSDVFTVLISYAVMFLYISLALGHIQSWNRVLVDSKISLGIAGILIVLSSVTCSLGIFSYIGMPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFGALSSMPAVHTFSLFAGMAVLIDFLLQITCFVSFLGLDIKRQEKNRLDILCCVRGPDDGQESQASESYLFRFFKNAFAPFLLTDWLRPVVMAVFVGILSFSIAVVNKVEIGLDQSLSMPNDSYVIDYFKSLGQYLHSGPPVYFVLEEGYNYSSRRG-QNMVCGGMGCDNDSLVQQIFNAAELDTYTRVGFAPSSWIDDYFDWVSPQSSCCRLYNVTHQFCNAS 971 HSP 2 Score: 197.593 bits (501), Expect = 7.967e-50 Identity = 104/230 (45.22%), Postives = 153/230 (66.52%), Query Frame = 0
Query: 1031 SCIKC-PNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
+C++C P + + +RP K F +++ FL DNP +C K GHAAYS +V + ++++ + A+ FMT+HTILKT DY +AL+ AR ++S I ++ +D +VFPYS+FYVFYEQYLT+ D I +L VS SI +VT + G + +++I+ + IAMIL+N+ G+M+ W ISLNAVSLVNLVM GISVEFCSHI +AFT S + +++ RA+ +
Sbjct: 976 TCVRCRPLTPEG--KQRPQGKEFMKFLPMFLSDNPNPKCGKGGHAAYSSAVNIMG-----DDTY----IGATYFMTYHTILKTSADYIDALKKARLIASNITETMRSKGSD----YRVFPYSVFYVFYEQYLTIIDDAIFNLSVSLGSIFLVTLVALGCELWSAVIMCLTIAMILVNMFGVMWLWGISLNAVSLVNLVMTCGISVEFCSHITRAFTMSTKGSRVSRAEEA 1190
BLAST of EMLSAG00000001950 vs. GO
Match: - (symbol:NPC1 "Niemann-Pick type C1 disease protein" species:9986 "Oryctolagus cuniculus" [GO:0005635 "nuclear envelope" evidence=ISS] [GO:0005783 "endoplasmic reticulum" evidence=ISS] [GO:0005887 "integral component of plasma membrane" evidence=ISS] [GO:0007041 "lysosomal transport" evidence=ISS] [GO:0008206 "bile acid metabolic process" evidence=ISS] [GO:0042632 "cholesterol homeostasis" evidence=ISS] [GO:0048471 "perinuclear region of cytoplasm" evidence=ISS] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 GO:GO:0005783 GO:GO:0048471 GO:GO:0007165 GO:GO:0005887 GO:GO:0005635 GO:GO:0008206 GO:GO:0042632 GO:GO:0007041 GO:GO:0030301 GO:GO:0008158 eggNOG:NOG149152 CTD:4864 HOVERGEN:HBG003913 TIGRFAMs:TIGR00917 HOGENOM:HOG000036674 EMBL:AF202730 RefSeq:NP_001075540.1 UniGene:Ocu.2405 ProteinModelPortal:Q9TT75 STRING:9986.ENSOCUP00000008488 GeneID:100008746 Uniprot:Q9TT75) HSP 1 Score: 570.081 bits (1468), Expect = 2.857e-178 Identity = 344/990 (34.75%), Postives = 517/990 (52.22%), Query Frame = 0
Query: 21 IWFENCSQSPYLENNADKWLNCAYDGEAKEAPLLK-----LERICP-HLDPSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHF---ETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGVNG-SEPCSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDF-LGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENG--ITLKDICHAPLEPISDGG--IPVQPYYMLGGFIPENEP---FPQNPSYHE--------------------------ASAVVISIMINNYDHNSPNP--------------EEIKKLEKALEWEKAYY----------MDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTI-DDSCCKYRAVDMSVCQSN 941
+W+ C + + DK NC Y G K PL K ++ +CP + +CC +QL ++ N + L RCP+C +N FC +TC P+QS FL V + + T + + + + YY+ F +Y++C+ V PS + AL L+CGK + C+ W Y+ +NG PF I +FS P+ G++ N + C+ V+ + PCSC DC C P + + G+D IM I ++ +F A + + + + TP+ N + TS KG L GA E L FT WG+FC + P VI SL +G+ ++ VTT+PI+LW++PSS++R +++FFD F PF+R Q+I++A + + Y + G FGP K + L +L+LQ IE+I N +TL+DIC APL P + + V Y+ + ++E F YH V +++ YD + N + +KL++A WEK + + I+FT+ERSIEDEL +E+ D+ T+ +SY +MF+YI+ +LG + +RF+V+SK++LG+ G++IVL SVA S+GIF +I +P TLI+ E+IPFLVLAVG DNIFI+VQT QRD R ET + +GR++GEVAPS+ L+S E+ FFLG +S MPAV F+L+AGMA+ IDFL+Q+TCF+SL+ LD+ RQ N D++CC RG++ E +++ FK+ Y+P ++K+W+R V+ +F G S+AV ++E+GLDQ LSMPDDS+V+ YF + +YL GPPVYFV++ + SL G QN CGG GC ++SL I ++ T I SWIDDY W SCC+ V C ++
Sbjct: 35 VWYGECGIA-----SGDKRYNCQYSGPPK--PLPKDGYDLIQELCPGFFFDNVSLCCDVQQLQTLKDNLQLPLQFLSRCPSCFYNLMNLFCELTCSPRQSQFL--NVTATEAYVDPATNQTKTNVKELQYYIGQRFADAMYNACRDVEAPSSNDKALGLLCGKDANA-CNATNWIEYMFDKNNGQAPFTITPIFS----DLPV-RGMEPMNNATKGCNEAVDEVTGPCSCQDCSVVCGPKPQPPPPPIPWRIFGLDAMYVIMWITYMAFLFMFFGTFFAVWCYRKRY----------FVSEYTPIDSNIAFSVNTSD------------KGEASCCDLL------GAAFEGCLRRLFTRWGSFCVRNPGCVIFFSLGFIAACSSGLVYVRVTTNPIDLWSAPSSQARQDKEFFDAHFGPFFRTEQLIIRAPHTNKHTYQPYPSGADVPFGPPLDK-QILHQVLDLQTAIEDITASYNNETVTLQDICLAPLSPYNKNCTILSVLNYFQNSHSMLDHEQGDDFFVYADYHTHFLYCVRVPASLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVSNYYNDTEKLQRAKAWEKEFINFVKNYENPNLTISFTAERSIEDELDRESNSDVFTVVISYAVMFLYISLALGHIKSCRRFLVDSKVSLGIAGILIVLSSVACSLGIFSYIGIPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLQGETLDQQLGRVLGEVAPSIFLSSFAETVAFFLGGLSVMPAVHTFSLFAGMAVFIDFLLQITCFVSLLGLDIKRQEKNQLDVLCCFRGAEAGTSIQASESYLFRFFKNSYSPLLLKDWMRPIVIAVFVGVLSFSIAVLNKVEIGLDQSLSMPDDSYVVDYFKSLGQYLHAGPPVYFVLEEGHNYTSLQG-QNMVCGGLGCDNDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQSSCCRVSNVTEQFCNAS 979 HSP 2 Score: 174.481 bits (441), Expect = 1.366e-42 Identity = 101/274 (36.86%), Postives = 160/274 (58.39%), Query Frame = 0
Query: 987 NSSKNGVLPESMFSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKC-PNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
N ++ G P S Y + + ++V + + +C++C P + + +RP + F R++ FL DNP +C K GHAAY +V + + + V A+ FMT+HT+L+T D+ +A++ A+ I + + K +VFPYS+FYVFYEQYLT+ D + +L VS ++ +V +L G + +++I+ V I MIL+N+ G+M+ W ISLNAVSLVNLVM+ GISVEFCSHI +AFT S + +++ RA+ +
Sbjct: 940 NYTRIGFAPSSWIDDYFDWVKPQSSCCRVSNVTEQFCNASVVDPACVRCRPLTPEG--KQRPQGEDFMRFLPMFLSDNPNPKCGKGGHAAYGTAVNILGNGTE---------VGATYFMTYHTVLQTSADFIDAMKKAQL----IAGNATATMGLKGSRCRVFPYSVFYVFYEQYLTILDDAVFNLGVSLGAVFVVAVVLLGCELWSAVIMCVTITMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSGKGSRVARAEEA 1198
BLAST of EMLSAG00000001950 vs. GO
Match: - (symbol:NPC1L1 "Uncharacterized protein" species:9913 "Bos taurus" [GO:0006695 "cholesterol biosynthetic process" evidence=IEA] [GO:0008158 "hedgehog receptor activity" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0017137 "Rab GTPase binding" evidence=IEA] [GO:0030299 "intestinal cholesterol absorption" evidence=IEA] [GO:0031489 "myosin V binding" evidence=IEA] [GO:0042157 "lipoprotein metabolic process" evidence=IEA] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 GO:GO:0016021 GO:GO:0007165 GO:GO:0006695 GO:GO:0042157 GO:GO:0030299 GO:GO:0008158 GeneTree:ENSGT00680000099777 OrthoDB:EOG7QRQT0 TreeFam:TF300416 TIGRFAMs:TIGR00917 CTD:29881 KO:K14461 OMA:LQMTAFV EMBL:DAAA02011180 RefSeq:XP_002686936.1 RefSeq:XP_588051.4 Ensembl:ENSBTAT00000061036 GeneID:539550 KEGG:bta:539550 NextBio:20878066 Uniprot:E1BPS5) HSP 1 Score: 471.47 bits (1212), Expect = 1.893e-141 Identity = 320/1000 (32.00%), Postives = 504/1000 (50.40%), Query Frame = 0
Query: 18 GRXIWFENCSQSPYLENNADKWLN--CAYDGEAKEAP---LLKLERICPHL---DPSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQ-GQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEG--IQFYNTVVESCDVGV-NGSEPCSCADCESAC----EPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKE--EFLFPLLELQKNIENIKTKEN-GITLKDICHAPLEP----ISDGGIPVQPYYM--------------LGGFIPE-----------NEPFPQNPSYHEASAVVISIM---------------------------INNYDHNSPNPEEIKKLEKALEWEKAYY-------------MDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTIDDSCCK 929
G +++ C ++P L + N C + A+ L L+ ICP L + CCS KQL ++ + I+ ++L RCP C NF C TC P QS F+ +V+T ++Q +V++ +Y F ++ Y+SC V P+ + A+ MCG +G LC+ RW + G SNG P I + ++ EG IQ N V C+ +G+ CSC DC ++C +P + T + + ++G++ ++ II ++ A ++ S++ + G TP S+NL R L F WGT+ A +P+ ++ VS+ + + L G+ ++ +TTDP+ELW++P+S +R E+ F DK F PF+R +QV + A + S++YD L K+F I + + L E ++++ +E ++L+D C+APL P +SD + Y L G + N P +Y + +A+ +S M I + N+ P + KL +A WE A+ + F +ERS+EDE+ T D+ AVSY+++F+YI+ +LG ++W+R V+SK TLGLGGV +VL +V AS+G F ++ VP++L+I +++PFLVLAVG DNIFI V QR PR E H+GR +G VAPSMLL S++E+ CFFLGA++ MPAVR FAL +G A+L+DFL+Q++ F++L+SLD RQ + D ICC + ++K + EG++ + F+ FY PF++ R VV++F F SL I VGLDQ+L++P DS+++ YF F+ +Y VG PVYFV + + S N C AGC++ SL I + P+ +Y+A PA SW+DD++ W SCC+
Sbjct: 31 GYCAFYDECGKNPELSGSLASLSNVSCLDNSPARHITGDHLALLQSICPRLYTGASTTYACCSSKQLVALDMSLRITKALLTRCPACSDNFVSLHCHNTCSPNQSLFINVTRVVTQGDSQSQ---AVVAYEAFY-QRSFAEQTYNSCSRVRIPAAATLAVGSMCGVYGSALCNAQRWLNFQGDTSNGLAPLDITFHLWEPSQA----EGSTIQPLNDEVVPCNQSQGDGAAACSCQDCAASCPVIAQPRALDPT----FRLGRMEGSL-VLIIILCSLFVLLTAFLLRSRLAE--------------WCRGKRKTPKPKA--------------------------SINLAHRLSLSTHTLLSRCFQCWGTWVASWPLTILAVSVIVVVALAGGLAFIELTTDPVELWSAPNSLARREKAFHDKYFGPFFRTSQVFMTAPHRPSYRYDSLLLGPKNFSGILSSDLLLEVLELQERLRHLQVWSPEEQRNVSLRDTCYAPLNPHNASLSDCCVNSLLQYFQNNRTQLLLTANQTLSGQTAQVDWRDHFLYCANAPL----TYKDGTALALSCMADYGAPIFPFLAVGGYKGKDYSEAEALIMTFSLNNYPPGD-PKLAQAKLWEAAFLEEMRAFQRRTAGVFQVTFMAERSLEDEINSTTAEDLPVFAVSYLVIFLYISLALGSYSSWRRVPVDSKATLGLGGVAVVLGAVVASMGFFSYLGVPSSLVILQVVPFLVLAVGADNIFIFVLEYQRLPRRPGEEREAHIGRALGRVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGFAVLLDFLLQMSAFVALLSLDSRRQEASRMD-ICCCKTAQKLPPPSQDEGLLLRFFRKFYVPFLLHWLTRVVVVLLFLALFAASLYFMCYINVGLDQQLALPKDSYLIDYFLFMNRYFEVGAPVYFVT-TGGYNFSSEEGMNAICSSAGCNNFSLTQKIQYATDFPDMSYLAIPASSWVDDFIDWLTSSSCCR 970 HSP 2 Score: 147.517 bits (371), Expect = 2.857e-34 Identity = 86/212 (40.57%), Postives = 124/212 (58.49%), Query Frame = 0
Query: 1046 RPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAK 1257
RP + F +Y+ WFL D P +CPK G AAYS SV + + Q ++AS FM ++ LK +D+ EALR R L++ I + + +VFPYS+ VFYEQYLT+ + + L + + +V L G D + ++ + I MIL++ +G M W+IS NAVSL+NLV AVGISVEF SHI ++F S + T++ RAK
Sbjct: 1004 RPSVEQFHKYLPWFLSDEPNIKCPKGGLAAYSTSVNMSSDGQ----------ILASRFMAYNKPLKNSRDFTEALRATRALAANITADLR-KVPGTDPDFEVFPYSVTNVFYEQYLTIVPEGLFMLTICLVPTFVVCCFLLGMDVRSGLLNLFSIIMILVDTVGFMMLWDISYNAVSLINLVTAVGISVEFVSHITRSFAISTKPTRLERAK 1204
BLAST of EMLSAG00000001950 vs. GO
Match: - (symbol:NPC1 "Niemann-Pick C1 protein" species:9606 "Homo sapiens" [GO:0008158 "hedgehog receptor activity" evidence=IEA] [GO:0016021 "integral component of membrane" evidence=IEA] [GO:0030301 "cholesterol transport" evidence=IEA] InterPro:IPR000731 InterPro:IPR003392 InterPro:IPR004765 Pfam:PF02460 PROSITE:PS50156 GO:GO:0016021 GO:GO:0007165 GO:GO:0030301 GO:GO:0008158 UniGene:Hs.464779 UniGene:Hs.715623 HGNC:HGNC:7897 HOVERGEN:HBG003913 TIGRFAMs:TIGR00917 HOGENOM:HOG000036674 EMBL:AC026634 EMBL:AC010853 EMBL:AK293779 ProteinModelPortal:B4DET3 PRIDE:B4DET3 Ensembl:ENST00000412552 UCSC:uc010xaz.2 NextBio:35471309 ArrayExpress:B4DET3 Uniprot:B4DET3) HSP 1 Score: 459.144 bits (1180), Expect = 2.479e-140 Identity = 245/594 (41.25%), Postives = 362/594 (60.94%), Query Frame = 0
Query: 357 ADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDF-LGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENG--ITLKDICHAPLEPISDGG--IPVQPYYMLGGFIPENEP---FPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAYYMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTI-DDSCCKYRAVDMSVCQSN 941
A E L FT WG+FC + P VI SL +G+ ++ VTT+P++LW++PSS++R+E+++FD+ F PF+R Q+I++A Y + G FGP + L +L+LQ IENI + +TL+DIC APL P + + V Y+ + +++ F YH + + + N+ N NP + I+FT+ERSIEDEL +E+ D+ T+ +SY IMF+YI+ +LG + +R +V+SK++LG+ G++IVL SVA S+G+F +I +P TLI+ E+IPFLVLAVG DNIFI+VQ QRD R ET + +GR++GEVAPSM L+S +E+ FFLGA+S MPAV F+L+AG+A+ IDFL+Q+TCF+SL+ LD+ RQ N DI CCVRG++ E +++ FK+ Y+P ++K+W+R V+ IF G S+AV ++++GLDQ LSMPDDS+++ YF I +YL GPPVYFV++ + S G QN CGG GC+++SL I ++ T I SWIDDY W SCC+ + C ++
Sbjct: 79 AAFEGCLRRLFTRWGSFCVRNPGCVIFFSLVFITACSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIRAPLTDKHIYQPYPSGADVPFGPPLDIQ-ILHQVLDLQIAIENITASYDNETVTLQDICLAPLSPYNTNCTILSVLNYFQNSHSVLDHKKGDDFFVYADYH--THFLYCVRFINFVKNYKNPN----------------LTISFTAERSIEDELNRESDSDVFTVVISYAIMFLYISLALGHMKSCRRLLVDSKVSLGIAGILIVLSSVACSLGVFSYIGLPLTLIVIEVIPFLVLAVGVDNIFILVQAYQRDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLGALSVMPAVHTFSLFAGLAVFIDFLLQITCFVSLLGLDIKRQEKNRLDIFCCVRGAEDGTSVQASESCLFRFFKNSYSPLLLKDWMRPIVIAIFVGVLSFSIAVLNKVDIGLDQSLSMPDDSYMVDYFKSISQYLHAGPPVYFVLEEGHDYTSSKG-QNMVCGGMGCNNDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQSSCCRVDNITDQFCNAS 652 HSP 2 Score: 199.134 bits (505), Expect = 1.139e-50 Identity = 112/294 (38.10%), Postives = 170/294 (57.82%), Query Frame = 0
Query: 966 GGNSVNDFDDYDHEEEEKEESNSSKNGVLPESMFSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKC-PNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVR-LKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAK 1257
GG N+ + N ++ G P S Y + + +++ + + +C++C P + + +RP F R++ FL DNP +C K GHAAYS +V L H + V A+ FMT+HT+L+T D+ +AL+ AR ++S + ++ N +VFPYS+FYVFYEQYLT+ DTI +L VS +I +VT +L G + +++I+ IAM+L+N+ G+M+ W ISLNAVSLVNLVM+ GISVEFCSHI +AFT SM+ +++ RA+
Sbjct: 592 GGMGCNNDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQSSCCRVDNITDQFCNASVVDPACVRCRPLTPEG--KQRPQGGDFMRFLPMFLSDNPNPKCGKGGHAAYSSAVNILLGHGTR---------VGATYFMTYHTVLQTSADFIDALKKARLIASNVTETMGIN----GSAYRVFPYSVFYVFYEQYLTIIDDTIFNLGVSLGAIFLVTMVLLGCELWSAVIMCATIAMVLVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRVERAE 870
BLAST of EMLSAG00000001950 vs. C. finmarchicus
Match: gi|592809975|gb|GAXK01144593.1| (TSA: Calanus finmarchicus comp58031_c0_seq1 transcribed RNA sequence) HSP 1 Score: 1045.8 bits (2703), Expect = 0.000e+0 Identity = 635/1389 (45.72%), Postives = 846/1389 (60.91%), Query Frame = 0
Query: 18 GRXIWFENCSQSP-YLENNADKWLNCAYDGEAKEAPLLKLE---RICPHLDPSEG----VCCSEKQLDVMEKNFNISASILGR-CPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSN----HFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGVN-GSEPCSCADCESAC--EPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPXXXXXXXXXXXXX--------XXXXHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNL-----SSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENI--KTKENGIT-----LKDICHAPLEPI-----------------------------SDGGIPVQPYYMLGGFIPENEPF------------------PQNP------------------SYHEASAVVISIMINNYDHNSPNPXXXXXXXXXXXXXXXY--------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENT--TWKRFMVESKXXXXXXXXXXXXXXXAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSS--NVDLSLPGIQNKFC-GGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTIDD-----SCCKYRAVDMSVCQSNGESKAKAQSALSFIDKFFENDDFFGGNSVNDFDDYDHXXXXXXXXXXXXXGVLPESMFSKXXXXXXXXXXXXXXXSVQTKKGRSKRATDS-------------------------CIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINXXXXXXXXXXXXTFILTGFDFLTSXXXXXXXXXXXXNLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRA 1256
G+ +W++ C Q P Y ++ +L C YDG+AK A ++E +CPHL P +G +CCS QL+ M+KNF + ++G+ CPTC +NF+KNFC +TCHP+QS F++ + ++ QE+ ++ +VTY+V++EF R Y+SCK V P+ S T + L+CG +G K C+ RWF Y+GS+SNG++PFQI+Y + + ++N +C++ G C CADC AC P F + F IV GVDG +FIM I+FVVG IIF+AIV AS+ L T+SNL + DDS+Y P S + T ++ D M L+ + + GA +E + NFFT+WGT AKYP+PVII+S++ A+GL TG+ +L VTTDPIELWASP+SRSRVE+DFFD TFRPFYR QVI+ AK + + F + D L FGPIF+K F+ +L+LQ+ IE + K KE+ T LK +C+ PL P +DG +P Y+ N P P NP YH+A AVV+SI+++NYD S +P +I+ LE+A+EWEK + YM+IAF SERSIEDEL KETYGDI TIA+SYIIMF+YITFSLG+ + T FM+ESKITLGLGGV+IVL+SVAASIG FGF+ VPATLIIFEIIPFLVLAVG DNIFI+VQT QR+PR E+H EHVGR+VGEVAPSMLL+SV+ESTCFFLGA+SDMPAVRAFALYAG+AL +DFLMQ+TCF+SL+SLDM RQ N +DIICCVRGSKK+ Q+ EG++++LFKH Y PF+MK+WVRA+V++IFFGW C+S+AV P+IE+GLD ++SMPD+S+VLKYFTF+++YLSVGPPVYFVV+++ +DLS QNK C G GCS+ SL I W K PE TYIA WID Y+ W D CC++ C S+ ++ G+S+ D + D +K G L +SMF DE + +T K R KR DS C+ C + +RP + F ++WFL+ NPGE+CP AGHAAY SV+L + + +V +SN M FH+ILKT KDYY AL AR L+ + +N N TD V +FPYS+FYVFYEQYLTMW DT+ L +S +I +VTF+L GFD ++S I +++I +I++NL G+MY+W+I+LNAVSLVNLVMAVGISVEFCSH+ +AF+ ++ + + RA
Sbjct: 425 GQCVWYDKCGQDPDYPPSDTQHYLMCKYDGQAKSASHKQIEILQEVCPHLLPEDGSLPELCCSLNQLEDMKKNFELPKGLIGQTCPTCYYNFRKNFCDVTCHPRQSNFVRVDKVAKGPGDGDYKGQEK-EMVKSVTYFVSEEFNDRTYESCKNVQFPAQSDTVMGLLCGAYGSKKCTAKRWFDYMGSISNGYSPFQINYEYGSSQTSG---DNHTYHNPSATACNLPAQPGMSACGCADCPQACTVNIPQFADRDPNFQIVRGVDGLVFIMIIVFVVGSIIFVAIVCASETL-TKSNLEI--RDDDSLYGDIPTECQKDNGSRRNSVTTPLRELPSPSRISYINDPNEEKLTMDDLSFLDKLGASVENNMTNFFTWWGTLAAKYPLPVIILSIAFAVGLSTGVIYLEVTTDPIELWASPTSRSRVEKDFFDSTFRPFYRTAQVIIHAKEMPEHGVTRFNFTDHLRNQLDFGPIFNK-NFMKEVLKLQQKIEELEFKYKESDGTDQTYNLKKVCNKPLSPEINECNIQNVLAYWQDDEALLEKEKYDPEGNDGNVPRTWTYLDHFLACANNPTLTSQSDKLNIGCMSKWGGPVNPYYCLGGFIPKGSSFPENPEYHKADAVVMSIIVDNYDPKSKDPNDIRGLERAMEWEKVFIDFMHDWEENEKPEYMEIAFNSERSIEDELDKETYGDIVTIAISYIIMFVYITFSLGQTSKCTVSMFMIESKITLGLGGVMIVLISVAASIGTFGFVGVPATLIIFEIIPFLVLAVGVDNIFILVQTYQREPRKEYESHAEHVGRVVGEVAPSMLLSSVSESTCFFLGALSDMPAVRAFALYAGVALFVDFLMQITCFVSLLSLDMMRQESNRFDIICCVRGSKKDQEQS--EGMLFRLFKHLYGPFLMKKWVRASVIVIFFGWACSSIAVVPKIEIGLDAEISMPDNSYVLKYFTFLKEYLSVGPPVYFVVNNTRGQLDLSSEKDQNKLCLGLPGCSENSLAGQIFNWQKAPESTYIATAPMPWIDGYITWAKADVTEGVRCCRHYKDKAGFCPSHIVNQP--------------------GSSIEDDEGKD-------PGGDAKEGQLDDSMFEN-------YDEFYYDVTEKTNKSRHKRQADSAYFDYYGDYGDYGDTSAGNSYLTGTCVPCETT-HLDSQQRPSAEQFGETIEWFLKANPGEQCPSAGHAAYGASVKLANNGGSN-------SVRSSNMMAFHSILKTSKDYYMALARARELTDNVMEFVN-NGTDPEDHVNIFPYSVFYVFYEQYLTMWRDTLQQLSISLAAIFLVTFVLMGFDLVSSCINLLIIVLIVLNLGGLMYWWHITLNAVSLVNLVMAVGISVEFCSHMTRAFSVNIGKDRTERA 4432
BLAST of EMLSAG00000001950 vs. C. finmarchicus
Match: gi|592765110|gb|GAXK01189458.1| (TSA: Calanus finmarchicus comp620364_c3_seq2 transcribed RNA sequence) HSP 1 Score: 733.791 bits (1893), Expect = 0.000e+0 Identity = 441/953 (46.27%), Postives = 598/953 (62.75%), Query Frame = 0
Query: 13 LKVACGRXIWFENCSQSP-YLENNADKWLNCAYDGEAKEAP---LLKLERICPHLDPSEG----VCCSEKQLDVMEKNFNISASILGR-CPTCLHNFKKNFCAMTCHPQQSYFLQ--GQVMTSNHFE-TQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVF-SGETRHHPIPEGIQFYNTVVESCDVGVN-GSEPCSCADCESACE--PPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIV-IASKILKTQSNLFMLPDGDDSIYDGTPVTPXXXXXXXXXXXXXXXXXHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAK-----NLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIK---TKENGI----TLKDICHAPLEPI-----------------------------SDGGIPVQPYYMLGGFIPENEP------------------------------FPQNPSY------HEASAVVISIMINNYDHNSPNPXXXXXXXXXXXXXXXY--------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGE--NTTWKRFMVESKXXXXXXXXXXXXXXXAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLS 855
+ V G+ IW + C P Y +++ +L C YDG A++ L ++ ICPHL +G +CCS QL M+KNF + A ++ + CPTC +NF+KNFC +TCHP QS F++ G V E E +++ VTY+V++EF R Y+SCK V PS S T + L+CG G K C+ RWF Y+GS++NG++PFQI+Y + SG T P+ ++N V C + G C CADC AC+ P F V + I PGVDG F M IIF VG +IF+ I+ + + K + NL + P ++S+ + ++ + + Q +N SN EV + LN + R GA LE + FT+WGT A YPIPVII+S +AI L TGI +L VTT+PIELWASP+SRSRVE+DFFD FRPFYR +QVI+ AK N++ F + D L GPIF K FL +L+LQK IE+++ +E+ + LK +C+ PL P SDG +P Y+ N P P++ S+ H+A AVV++I++NNYD S E++K LE+A+ WEK + YMDIAF SERSIEDEL KETYGDI TI +SYIIMF+YITF+LG+ + ++ FM+ESK+TLGLGGV+IVLLSV ASIG+F F+ VPATLIIFEIIPFLVLA+G DNIFI+VQT QR+PR E+H EHVGRIVGEVAPSML++S++ESTCFFLGA+SDMPAV+AFALYAGMA+++DFLMQ+TCF+SL+SLD++R+ + +DI+CC++G K ++ G+G++Y FKH Y PF+MKEWVRA V+IIFFGW C+S+AV P+IEVGLD ++++PDDSF+ KYF+F+++YLS
Sbjct: 294 ISVPPGQCIWHDRCGPDPDYPPSDSQHYLMCQYDGPARQVTQEMALIVQDICPHLSNKDGSLPSLCCSLNQLQDMKKNFELPAGLIAQTCPTCYYNFRKNFCDLTCHPHQSEFVRVDGVVHGLGDGEYAGENKTMVKAVTYHVSEEFNTRTYESCKNVQFPSTSDTVMGLLCGPHGSKDCTAKRWFDYMGSITNGYSPFQINYDYGSGHT-----PDNYTYHNPPVTPCQMSPQPGVAACGCADCPQACKINIPQFITQDVNWQIFPGVDGLGFFMFIIFFVGTVIFITILCVVGRRNKFKINL-VHPVNEESVTKNVVQEISLNQRNGSYQSSNQPSNPEVKPPS----LDDLNFLDRLGAKLETKMTRLFTWWGTVAATYPIPVIIISTGMAIVLSTGILYLQVTTNPIELWASPTSRSRVEKDFFDSNFRPFYRTSQVIIHAKEMDEYNITRFNFTDHLRNNLEMGPIFQK-TFLKEVLKLQKKIESLEFVYKEEDDMDYKYNLKTVCNKPLSPEIEECNIQNVLAYWQDDEELLDAEKYDPVGSDGDLPRTWNYLDHFLACANNPTLTSESDKLNIRCMARWGGPVQPYYCLGGFIPKDTSFPENPDYHQADAVVMTIILNNYDSQSEEEEDVKGLERAMAWEKTFIEFMLEWEEKEKPIYMDIAFNSERSIEDELEKETYGDIMTIVLSYIIMFVYITFTLGQAGSCSFSTFMIESKVTLGLGGVLIVLLSVTASIGVFAFVGVPATLIIFEIIPFLVLAIGVDNIFILVQTYQREPRKDDESHAEHVGRIVGEVAPSMLVSSISESTCFFLGALSDMPAVQAFALYAGMAIMLDFLMQITCFVSLLSLDISREENRRFDILCCLKGDKN--EESSGDGMIYNFFKHLYGPFLMKEWVRALVIIIFFGWACSSVAVLPKIEVGLDPEITIPDDSFLRKYFSFLKEYLS 3113
BLAST of EMLSAG00000001950 vs. C. finmarchicus
Match: gi|592765111|gb|GAXK01189457.1| (TSA: Calanus finmarchicus comp620364_c3_seq1 transcribed RNA sequence) HSP 1 Score: 731.48 bits (1887), Expect = 0.000e+0 Identity = 440/951 (46.27%), Postives = 597/951 (62.78%), Query Frame = 0
Query: 15 VACGRXIWFENCSQSP-YLENNADKWLNCAYDGEAKEAP---LLKLERICPHLDPSEG----VCCSEKQLDVMEKNFNISASILGR-CPTCLHNFKKNFCAMTCHPQQSYFLQ--GQVMTSNHFE-TQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVF-SGETRHHPIPEGIQFYNTVVESCDVGVN-GSEPCSCADCESACE--PPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIV-IASKILKTQSNLFMLPDGDDSIYDGTPVTPXXXXXXXXXXXXXXXXXHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAK-----NLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIK---TKENGI----TLKDICHAPLEPI-----------------------------SDGGIPVQPYYMLGGFIPENEP------------------------------FPQNPSY------HEASAVVISIMINNYDHNSPNPXXXXXXXXXXXXXXXY--------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGE--NTTWKRFMVESKXXXXXXXXXXXXXXXAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLS 855
V G+ IW + C P Y +++ +L C YDG A++ L ++ ICPHL +G +CCS QL M+KNF + A ++ + CPTC +NF+KNFC +TCHP QS F++ G V E E +++ VTY+V++EF R Y+SCK V PS S T + L+CG G K C+ RWF Y+GS++NG++PFQI+Y + SG T P+ ++N V C + G C CADC AC+ P F V + I PGVDG F M IIF VG +IF+ I+ + + K + NL + P ++S+ + ++ + + Q +N SN EV + LN + R GA LE + FT+WGT A +PIPVII+S +AI L TGI +L VTT+PIELWASP+SRSRVE+DFFD FRPFYR +QVI+ AK N++ F + D L GPIF K FL +L+LQK IE+++ +E+ + LK +C+ PL P SDG +P Y+ N P P++ S+ H+A AVV++I++NNYD S E++K LE+A+ WEK + YMDIAF SERSIEDEL KETYGDI TI +SYIIMF+YITF+LG+ + ++ FM+ESK+TLGLGGV+IVLLSV ASIG+F F+ VPATLIIFEIIPFLVLA+G DNIFI+VQT QR+PR E+H EHVGRIVGEVAPSML++S++ESTCFFLGA+SDMPAV+AFALYAGMA+++DFLMQ+TCF+SL+SLD++R+ + +DI+CC++G K ++ G+G++Y FKH Y PF+MKEWVRA V+IIFFGW C+S+AV P+IEVGLD ++++PDDSF+ KYF+F+++YLS
Sbjct: 306 VPPGQCIWHDRCGPDPDYPPSDSQHYLMCQYDGPARQVTQEMALIVQDICPHLSNKDGSLPSLCCSLNQLQDMKKNFELPAGLIAQTCPTCYYNFRKNFCDLTCHPHQSEFVRVDGVVHGLGDGEYAGENKTMVKAVTYHVSEEFNTRTYESCKNVQFPSTSDTVMGLLCGPHGSKDCTAKRWFDYMGSITNGYSPFQINYDYGSGHT-----PDNYTYHNPPVTPCQMSPQPGVAACGCADCPQACKINIPQFITQDVNWQIFPGVDGLGFFMFIIFFVGTVIFITILCVVGRRNKFKINL-VHPVNEESVTKNVVQEISLNQRNGSYQSSNQPSNPEVKPPS----LDDLNFLDRLGAKLETKMTRLFTWWGTVAATHPIPVIIISTGMAIVLSTGILYLQVTTNPIELWASPTSRSRVEKDFFDSNFRPFYRTSQVIIHAKEMDEYNITRFNFTDHLRNNLEMGPIFQK-TFLKEVLKLQKKIESLEFVYKEEDDMDYKYNLKTVCNKPLSPEIEECNIQNVLAYWQDDEELLDAEKYDPVGSDGDLPRTWNYLDHFLACANNPTLTSESDKLNIRCMARWGGPVQPYYCLGGFIPKDTSFPENPDYHQADAVVMTIILNNYDSQSEEEEDVKGLERAMAWEKTFIEFMLEWEEKEKPIYMDIAFNSERSIEDELEKETYGDIMTIVLSYIIMFVYITFTLGQAGSCSFSTFMIESKVTLGLGGVLIVLLSVTASIGVFAFVGVPATLIIFEIIPFLVLAIGVDNIFILVQTYQREPRKDDESHAEHVGRIVGEVAPSMLVSSISESTCFFLGALSDMPAVQAFALYAGMAIMLDFLMQITCFVSLLSLDISREENRRFDILCCLKGDKN--EESSGDGMIYNFFKHLYGPFLMKEWVRALVIIIFFGWACSSVAVLPKIEVGLDPEITIPDDSFLRKYFSFLKEYLS 3119
BLAST of EMLSAG00000001950 vs. C. finmarchicus
Match: gi|592765108|gb|GAXK01189460.1| (TSA: Calanus finmarchicus comp620364_c3_seq4 transcribed RNA sequence) HSP 1 Score: 665.226 bits (1715), Expect = 0.000e+0 Identity = 410/905 (45.30%), Postives = 556/905 (61.44%), Query Frame = 0
Query: 13 LKVACGRXIWFENCSQSP-YLENNADKWLNCAYDGEAKEAP---LLKLERICPHLDPSEG----VCCSEKQLDVMEKNFNISASILGR-CPTCLHNFKKNFCAMTCHPQQSYFLQ--GQVMTSNHFE-TQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVF-SGETRHHPIPEGIQFYNTVVESCDVGVN-GSEPCSCADCESACE--PPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIV-IASKILKTQSNLFMLPDGDDSIYDGTPVTPXXXXXXXXXXXXXXXXXHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAK-----NLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIK---TKENGI----TLKDICHAPLEPI-----------------------------SDGGIPVQPYYMLGGFIPENEP------------------------------FPQNPSY------HEASAVVISIMINNYDHNSPNPXXXXXXXXXXXXXXXY--------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGE--NTTWKRFMVESKXXXXXXXXXXXXXXXAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRA 807
+ V G+ IW + C P Y +++ +L C YDG A++ L ++ ICPHL +G +CCS QL M+KNF + A ++ + CPTC +NF+KNFC +TCHP QS F++ G V E E +++ VTY+V++EF R Y+SCK V PS S T + L+CG G K C+ RWF Y+GS++NG++PFQI+Y + SG T P+ ++N V C + G C CADC AC+ P F V + I PGVDG F M IIF VG +IF+ I+ + + K + NL + P ++S+ + ++ + + Q +N SN EV + LN + R GA LE + FT+WGT A YPIPVII+S +AI L TGI +L VTT+PIELWASP+SRSRVE+DFFD FRPFYR +QVI+ AK N++ F + D L GPIF K FL +L+LQK IE+++ +E+ + LK +C+ PL P SDG +P Y+ N P P++ S+ H+A AVV++I++NNYD S E++K LE+A+ WEK + YMDIAF SERSIEDEL KETYGDI TI +SYIIMF+YITF+LG+ + ++ FM+ESK+TLGLGGV+IVLLSV ASIG+F F+ VPATLIIFEIIPFLVLA+G DNIFI+VQT QR+PR E+H EHVGRIVGEVAPSML++S++ESTCFFLGA+SDMPAV+AFALYAGMA+++DFLMQ+TCF+SL+SLD++R+ + +DI+CC++G K ++ G+G++Y FKH+Y PF+MK+WVRA
Sbjct: 294 ISVPPGQCIWHDRCGPDPDYPPSDSQHYLMCQYDGPARQVTQEMALIVQDICPHLSNKDGSLPSLCCSLNQLQDMKKNFELPAGLIAQTCPTCYYNFRKNFCDLTCHPHQSEFVRVDGVVHGLGDGEYAGENKTMVKAVTYHVSEEFNTRTYESCKNVQFPSTSDTVMGLLCGPHGSKDCTAKRWFDYMGSITNGYSPFQINYDYGSGHT-----PDNYTYHNPPVTPCQMSPQPGVAACGCADCPQACKINIPQFITQDVNWQIFPGVDGLGFFMFIIFFVGTVIFITILCVVGRRNKFKINL-VHPVNEESVTKNVVQEISLNQRNGSYQSSNQPSNPEVKPPS----LDDLNFLDRLGAKLETKMTRLFTWWGTVAATYPIPVIIISTGMAIVLSTGILYLQVTTNPIELWASPTSRSRVEKDFFDSNFRPFYRTSQVIIHAKEMDEYNITRFNFTDHLRNNLEMGPIFQK-TFLKEVLKLQKKIESLEFVYKEEDDMDYKYNLKTVCNKPLSPEIEECNIQNVLAYWQDDEELLDAEKYDPVGSDGDLPRTWNYLDHFLACANNPTLTSESDKLNIRCMARWGGPVQPYYCLGGFIPKDTSFPENPDYHQADAVVMTIILNNYDSQSEEEEDVKGLERAMAWEKTFIEFMLEWEEKEKPIYMDIAFNSERSIEDELEKETYGDIMTIVLSYIIMFVYITFTLGQAGSCSFSTFMIESKVTLGLGGVLIVLLSVTASIGVFAFVGVPATLIIFEIIPFLVLAIGVDNIFILVQTYQREPRKDDESHAEHVGRIVGEVAPSMLVSSISESTCFFLGALSDMPAVQAFALYAGMAIMLDFLMQITCFVSLLSLDISREENRRFDILCCLKGDKN--EESSGDGMIYNFFKHYYGPFLMKKWVRA 2969
BLAST of EMLSAG00000001950 vs. C. finmarchicus
Match: gi|592765109|gb|GAXK01189459.1| (TSA: Calanus finmarchicus comp620364_c3_seq3 transcribed RNA sequence) HSP 1 Score: 663.3 bits (1710), Expect = 0.000e+0 Identity = 409/903 (45.29%), Postives = 555/903 (61.46%), Query Frame = 0
Query: 15 VACGRXIWFENCSQSP-YLENNADKWLNCAYDGEAKEAP---LLKLERICPHLDPSEG----VCCSEKQLDVMEKNFNISASILGR-CPTCLHNFKKNFCAMTCHPQQSYFLQ--GQVMTSNHFE-TQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVF-SGETRHHPIPEGIQFYNTVVESCDVGVN-GSEPCSCADCESACE--PPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIV-IASKILKTQSNLFMLPDGDDSIYDGTPVTPXXXXXXXXXXXXXXXXXHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAK-----NLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIK---TKENGI----TLKDICHAPLEPI-----------------------------SDGGIPVQPYYMLGGFIPENEP------------------------------FPQNPSY------HEASAVVISIMINNYDHNSPNPXXXXXXXXXXXXXXXY--------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGE--NTTWKRFMVESKXXXXXXXXXXXXXXXAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRA 807
V G+ IW + C P Y +++ +L C YDG A++ L ++ ICPHL +G +CCS QL M+KNF + A ++ + CPTC +NF+KNFC +TCHP QS F++ G V E E +++ VTY+V++EF R Y+SCK V PS S T + L+CG G K C+ RWF Y+GS++NG++PFQI+Y + SG T P+ ++N V C + G C CADC AC+ P F V + I PGVDG F M IIF VG +IF+ I+ + + K + NL + P ++S+ + ++ + + Q +N SN EV + LN + R GA LE + FT+WGT A +PIPVII+S +AI L TGI +L VTT+PIELWASP+SRSRVE+DFFD FRPFYR +QVI+ AK N++ F + D L GPIF K FL +L+LQK IE+++ +E+ + LK +C+ PL P SDG +P Y+ N P P++ S+ H+A AVV++I++NNYD S E++K LE+A+ WEK + YMDIAF SERSIEDEL KETYGDI TI +SYIIMF+YITF+LG+ + ++ FM+ESK+TLGLGGV+IVLLSV ASIG+F F+ VPATLIIFEIIPFLVLA+G DNIFI+VQT QR+PR E+H EHVGRIVGEVAPSML++S++ESTCFFLGA+SDMPAV+AFALYAGMA+++DFLMQ+TCF+SL+SLD++R+ + +DI+CC++G K ++ G+G++Y FKH+Y PF+MK+WVRA
Sbjct: 306 VPPGQCIWHDRCGPDPDYPPSDSQHYLMCQYDGPARQVTQEMALIVQDICPHLSNKDGSLPSLCCSLNQLQDMKKNFELPAGLIAQTCPTCYYNFRKNFCDLTCHPHQSEFVRVDGVVHGLGDGEYAGENKTMVKAVTYHVSEEFNTRTYESCKNVQFPSTSDTVMGLLCGPHGSKDCTAKRWFDYMGSITNGYSPFQINYDYGSGHT-----PDNYTYHNPPVTPCQMSPQPGVAACGCADCPQACKINIPQFITQDVNWQIFPGVDGLGFFMFIIFFVGTVIFITILCVVGRRNKFKINL-VHPVNEESVTKNVVQEISLNQRNGSYQSSNQPSNPEVKPPS----LDDLNFLDRLGAKLETKMTRLFTWWGTVAATHPIPVIIISTGMAIVLSTGILYLQVTTNPIELWASPTSRSRVEKDFFDSNFRPFYRTSQVIIHAKEMDEYNITRFNFTDHLRNNLEMGPIFQK-TFLKEVLKLQKKIESLEFVYKEEDDMDYKYNLKTVCNKPLSPEIEECNIQNVLAYWQDDEELLDAEKYDPVGSDGDLPRTWNYLDHFLACANNPTLTSESDKLNIRCMARWGGPVQPYYCLGGFIPKDTSFPENPDYHQADAVVMTIILNNYDSQSEEEEDVKGLERAMAWEKTFIEFMLEWEEKEKPIYMDIAFNSERSIEDELEKETYGDIMTIVLSYIIMFVYITFTLGQAGSCSFSTFMIESKVTLGLGGVLIVLLSVTASIGVFAFVGVPATLIIFEIIPFLVLAIGVDNIFILVQTYQREPRKDDESHAEHVGRIVGEVAPSMLVSSISESTCFFLGALSDMPAVQAFALYAGMAIMLDFLMQITCFVSLLSLDISREENRRFDILCCLKGDKN--EESSGDGMIYNFFKHYYGPFLMKKWVRA 2975
BLAST of EMLSAG00000001950 vs. C. finmarchicus
Match: gi|592794335|gb|GAXK01160233.1| (TSA: Calanus finmarchicus comp142827_c0_seq2 transcribed RNA sequence) HSP 1 Score: 497.278 bits (1279), Expect = 1.570e-150 Identity = 282/518 (54.44%), Postives = 372/518 (71.81%), Query Frame = 0
Query: 441 KNLSSFKYDDFLGETKSFGP----IFHKEEFLFPLLELQKNIENIKTKENGITLKDICHAPLEPISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPXXXXXXXXXXXXXXXY--------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGE--NTTWKRFMVESKXXXXXXXXXXXXXXXAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSS--NVDLSLPGIQNKFC-GGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTIDDS-----CCKY 930
N ++ +DD K F P + +L L+ KN + ++ L D + + ++ G PV PYY+LGGFIPE FP++P Y ++ A+V+ I+INN+D +S E++K LE+A+ WE+ + Y+D+AFTSERS+EDEL +ETYGD++TIAVSYIIMFIYIT SLG+ + FM+ESKITLGL GV+IVLLSV ASIGIF VPATLIIFEIIPFLVLAVG DNIFI+VQT QRD + TET E VGR+VGEVAPSMLL+S+TESTCFFLGA+S MPAVRAFA+YAGMALLIDFLMQVT F++L+SLDMARQ +N +DI+CC+RGSKK+ EGV+Y++FKH YAP ++ +WVR A++I+FFG C+S+AV PRI +GLDQ+LSMP+DSFVLK+F ++++YLSVGPPVYFV++++ ++DL+ P +QN C G GC + SL +N W QP ++YIA +W+DDY+ W +S CC+Y
Sbjct: 1219 NNAWAYWHDDESLLDKEFKPSSDSVGRNLTYLDHFLDCVKNPSMVSQQDTHTDLGD-GNGGIGCLAKWGGPVNPYYVLGGFIPEGTTFPESPDYAKSQAIVMQIIINNFDPHSEKEEDVKGLERAMAWEEKFVEFMKDWVENEMPEYIDVAFTSERSVEDELDRETYGDVATIAVSYIIMFIYITLSLGQYGKFSLSGFMIESKITLGLFGVMIVLLSVFASIGIFAVAGVPATLIIFEIIPFLVLAVGVDNIFILVQTYQRDKKRPTETDEEQVGRVVGEVAPSMLLSSLTESTCFFLGALSGMPAVRAFAMYAGMALLIDFLMQVTSFVALMSLDMARQRNNKFDILCCIRGSKKDSEPV--EGVLYRVFKHLYAPALLSKWVRPAIMILFFGAACSSIAVVPRIGIGLDQELSMPEDSFVLKFFVYMKEYLSVGPPVYFVLNNTAGHLDLTDPSVQNLLCLGLGGCQENSLAGQVNSWRLQPNQSYIATAPMNWLDDYVTWVKTESDNNLQCCRY 2763 HSP 2 Score: 295.819 bits (756), Expect = 3.562e-81 Identity = 186/525 (35.43%), Postives = 275/525 (52.38%), Query Frame = 0
Query: 18 GRXIWFENCS-QSPYLENNADK--WLNCAYDGEAKEAPLLKLERI---CPHLDPSEG----VCCSEKQLDVMEKNFNISASILGR-CPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTS-----NHFE--TQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESC-DVGVNGSEPCSCADCESACE----PPHFEETQVGFY--IVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPXXXXXXXXXXXXXXXXXHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAK-----NLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENI----------KTKENGITLKDICHAPLEPIS 502
G+ IW++ C Y + ++ +LNC Y G AK A ++E I CPH+ +EG +CCS +QL ++ NF +++ CPTC +NF+KNFC MTC QQ+ F++ + N +E T + V ++ +VTY+V ++F ++DSCK V P+VS T + ++CG WG + C+P RWF +LGS+ NG+ PF I+Y F T ++++ V SC D S C CA+C +AC P E FY + G+DG IM ++F VG ++F+ I + PVT K + NL+ A + FFT+WG F A++P+ V+++SL+IA GLC G+ L +TTDPIELWASP+SRSRVE+DFFD FRPFYR + VI+KA + F + D G+ FG +F+K +FL L+LQ+ IENI +T E+ L IC++PL P++
Sbjct: 2779 GQCIWYDTCGWDQDYGPDGGNEVHFLNCHYTGPAKPASDEQVELIKELCPHM-YTEGEDLNLCCSIRQLKDLQLNFGTPKTLIEELCPTCWYNFRKNFCDMTCSDQQNKFVRTDHIVEGPGFDNGYENYTGQNVQMVKDVTYFVTEQFASDLFDSCKDVQFPAVSDTIMYMLCGSWGSEYCTPRRWFDFLGSVDNGYAPFTINYEFD--TDDDISITDFEYHSPEVISCQDTAPGYSTGCGCANCPAACSGSGVPEFNREDDKPFYDFKLGGLDGLSVIMGLVFSVGSVLFIGFSIV------------------CVPSVIPVT----------------------TKPKIGPKARTNLVNDA-------IEKFFTWWGKFAARHPVLVLVISLTIAFGLCCGVVKLKITTDPIELWASPTSRSRVEKDFFDTEFRPFYRTSLVIIKANENPSAGIEKFNFTDAYGKEYEFGAMFNK-KFLKEALKLQQKIENITFQYEETEGNETVEHTYDLTRICNSPLSPLN 4200 HSP 3 Score: 204.142 bits (518), Expect = 3.147e-52 Identity = 125/235 (53.19%), Postives = 162/235 (68.94%), Query Frame = 0
Query: 1030 DSCIKCPNSDDAIDLK--RPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRL---KAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINXXXXXXXXXXXXTFILTGFDFLTSXXXXXXXXXXXXNLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
D C+ C + D A D RP + F + FLE NPGE CPKAGH A++ +V+L ++ NES +YNV +SN M FHTIL+T +DYY AL+ AR L+ I IN N T++ + V VFPYSIFYVFYEQYLTMW DT+ S+ +S ++I +VTF+L GFD ++ II+ VI +ILINL +MY+WNI+LNAVSLVNLVMAVGISVEFCSHI + F + +I A+ S
Sbjct: 484 DGCVGCLD-DSAYDNHDFRPDSEEFSETISLFLEQNPGEFCPKAGHGAFADAVKLTQLESATANLNESL-KYNVASSNMMAFHTILRTSEDYYTALKRARELTDSITEMINANRTEEEK-VNVFPYSIFYVFYEQYLTMWKDTLISVGISLVTIFVVTFLLMGFDLRSATIILFVIILILINLGALMYWWNITLNAVSLVNLVMAVGISVEFCSHITRYFATHSHQDRIENARNS 1179
BLAST of EMLSAG00000001950 vs. C. finmarchicus
Match: gi|592794336|gb|GAXK01160232.1| (TSA: Calanus finmarchicus comp142827_c0_seq1 transcribed RNA sequence) HSP 1 Score: 497.278 bits (1279), Expect = 1.773e-150 Identity = 282/518 (54.44%), Postives = 372/518 (71.81%), Query Frame = 0
Query: 441 KNLSSFKYDDFLGETKSFGP----IFHKEEFLFPLLELQKNIENIKTKENGITLKDICHAPLEPISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPXXXXXXXXXXXXXXXY--------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGE--NTTWKRFMVESKXXXXXXXXXXXXXXXAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSS--NVDLSLPGIQNKFC-GGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTIDDS-----CCKY 930
N ++ +DD K F P + +L L+ KN + ++ L D + + ++ G PV PYY+LGGFIPE FP++P Y ++ A+V+ I+INN+D +S E++K LE+A+ WE+ + Y+D+AFTSERS+EDEL +ETYGD++TIAVSYIIMFIYIT SLG+ + FM+ESKITLGL GV+IVLLSV ASIGIF VPATLIIFEIIPFLVLAVG DNIFI+VQT QRD + TET E VGR+VGEVAPSMLL+S+TESTCFFLGA+S MPAVRAFA+YAGMALLIDFLMQVT F++L+SLDMARQ +N +DI+CC+RGSKK+ EGV+Y++FKH YAP ++ +WVR A++I+FFG C+S+AV PRI +GLDQ+LSMP+DSFVLK+F ++++YLSVGPPVYFV++++ ++DL+ P +QN C G GC + SL +N W QP ++YIA +W+DDY+ W +S CC+Y
Sbjct: 1239 NNAWAYWHDDESLLDKEFKPSSDSVGRNLTYLDHFLDCVKNPSMVSQQDTHTDLGD-GNGGIGCLAKWGGPVNPYYVLGGFIPEGTTFPESPDYAKSQAIVMQIIINNFDPHSEKEEDVKGLERAMAWEEKFVEFMKDWVENEMPEYIDVAFTSERSVEDELDRETYGDVATIAVSYIIMFIYITLSLGQYGKFSLSGFMIESKITLGLFGVMIVLLSVFASIGIFAVAGVPATLIIFEIIPFLVLAVGVDNIFILVQTYQRDKKRPTETDEEQVGRVVGEVAPSMLLSSLTESTCFFLGALSGMPAVRAFAMYAGMALLIDFLMQVTSFVALMSLDMARQRNNKFDILCCIRGSKKDSEPV--EGVLYRVFKHLYAPALLSKWVRPAIMILFFGAACSSIAVVPRIGIGLDQELSMPEDSFVLKFFVYMKEYLSVGPPVYFVLNNTAGHLDLTDPSVQNLLCLGLGGCQENSLAGQVNSWRLQPNQSYIATAPMNWLDDYVTWVKTESDNNLQCCRY 2783 HSP 2 Score: 295.819 bits (756), Expect = 3.701e-81 Identity = 186/525 (35.43%), Postives = 275/525 (52.38%), Query Frame = 0
Query: 18 GRXIWFENCS-QSPYLENNADK--WLNCAYDGEAKEAPLLKLERI---CPHLDPSEG----VCCSEKQLDVMEKNFNISASILGR-CPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTS-----NHFE--TQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESC-DVGVNGSEPCSCADCESACE----PPHFEETQVGFY--IVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPXXXXXXXXXXXXXXXXXHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAK-----NLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENI----------KTKENGITLKDICHAPLEPIS 502
G+ IW++ C Y + ++ +LNC Y G AK A ++E I CPH+ +EG +CCS +QL ++ NF +++ CPTC +NF+KNFC MTC QQ+ F++ + N +E T + V ++ +VTY+V ++F ++DSCK V P+VS T + ++CG WG + C+P RWF +LGS+ NG+ PF I+Y F T ++++ V SC D S C CA+C +AC P E FY + G+DG IM ++F VG ++F+ I + PVT K + NL+ A + FFT+WG F A++P+ V+++SL+IA GLC G+ L +TTDPIELWASP+SRSRVE+DFFD FRPFYR + VI+KA + F + D G+ FG +F+K +FL L+LQ+ IENI +T E+ L IC++PL P++
Sbjct: 2799 GQCIWYDTCGWDQDYGPDGGNEVHFLNCHYTGPAKPASDEQVELIKELCPHM-YTEGEDLNLCCSIRQLKDLQLNFGTPKTLIEELCPTCWYNFRKNFCDMTCSDQQNKFVRTDHIVEGPGFDNGYENYTGQNVQMVKDVTYFVTEQFASDLFDSCKDVQFPAVSDTIMYMLCGSWGSEYCTPRRWFDFLGSVDNGYAPFTINYEFD--TDDDISITDFEYHSPEVISCQDTAPGYSTGCGCANCPAACSGSGVPEFNREDDKPFYDFKLGGLDGLSVIMGLVFSVGSVLFIGFSIV------------------CVPSVIPVT----------------------TKPKIGPKARTNLVNDA-------IEKFFTWWGKFAARHPVLVLVISLTIAFGLCCGVVKLKITTDPIELWASPTSRSRVEKDFFDTEFRPFYRTSLVIIKANENPSAGIEKFNFTDAYGKEYEFGAMFNK-KFLKEALKLQQKIENITFQYEETEGNETVEHTYDLTRICNSPLSPLN 4220 HSP 3 Score: 204.142 bits (518), Expect = 3.172e-52 Identity = 125/235 (53.19%), Postives = 162/235 (68.94%), Query Frame = 0
Query: 1030 DSCIKCPNSDDAIDLK--RPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRL---KAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINXXXXXXXXXXXXTFILTGFDFLTSXXXXXXXXXXXXNLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
D C+ C + D A D RP + F + FLE NPGE CPKAGH A++ +V+L ++ NES +YNV +SN M FHTIL+T +DYY AL+ AR L+ I IN N T++ + V VFPYSIFYVFYEQYLTMW DT+ S+ +S ++I +VTF+L GFD ++ II+ VI +ILINL +MY+WNI+LNAVSLVNLVMAVGISVEFCSHI + F + +I A+ S
Sbjct: 504 DGCVGCLD-DSAYDNHDFRPDSEEFSETISLFLEQNPGEFCPKAGHGAFADAVKLTQLESATANLNESL-KYNVASSNMMAFHTILRTSEDYYTALKRARELTDSITEMINANRTEEEK-VNVFPYSIFYVFYEQYLTMWKDTLISVGISLVTIFVVTFLLMGFDLRSATIILFVIILILINLGALMYWWNITLNAVSLVNLVMAVGISVEFCSHITRYFATHSHQDRIENARNS 1199
BLAST of EMLSAG00000001950 vs. C. finmarchicus
Match: gi|592810949|gb|GAXK01143619.1| (TSA: Calanus finmarchicus comp525863_c1_seq1 transcribed RNA sequence) HSP 1 Score: 198.749 bits (504), Expect = 2.041e-51 Identity = 111/228 (48.68%), Postives = 157/228 (68.86%), Query Frame = 0
Query: 1029 TDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINXXXXXXXXXXXXTFILTGFDFLTSXXXXXXXXXXXXNLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRA 1256
T +C+ C N+ RPGP F + + WFL NP ++CP GHAAY +SVRL D+++ + V +SN M FHTILKT +D+Y AL AR L+ I ++N N T+ + V +FPYS+FYVFYEQYLTMW DT+ SL +S +I +VTF+ GFD ++S I +++I +I++N+ G+MY+WNI+LNA+SLVNLVM VGISVEFC H +AF+ ++ ++ RA
Sbjct: 1434 TGACLPC-NTTFLERGDRPGPDQFSQTIDWFLAANPSDKCPSGGHAAYGESVRL------DDDNGVRV-VTSSNMMAFHTILKTSEDFYMALSRARELADSIMQAVN-NGTEAEKQVNIFPYSVFYVFYEQYLTMWRDTLKSLAISITAIFLVTFVFMGFDIVSSFINLLIIILIVLNMGGLMYWWNITLNAISLVNLVMTVGISVEFCCHTTRAFSVNVGRDRVERA 2090 HSP 2 Score: 80.4925 bits (197), Expect = 2.444e-14 Identity = 42/93 (45.16%), Postives = 52/93 (55.91%), Query Frame = 0
Query: 857 GPPVYFVVDSSN--VDLSLPGIQNKFCGG-AGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTIDD-----SCCKYRAVDMSVCQSN 941
GPPVYFVV+++ +D SLP QNK C G GC ++SL I W K PEKTYIA WID Y+ W + CC++ D C SN
Sbjct: 2214 GPPVYFVVNNTQGQLDFSLPHDQNKLCLGLPGCQEDSLAGQIFNWQKVPEKTYIATAPMPWIDGYITWATAEVTEGVKCCRFYREDNQFCPSN 2492
BLAST of EMLSAG00000001950 vs. C. finmarchicus
Match: gi|592822728|gb|GAXK01131840.1| (TSA: Calanus finmarchicus comp1047552_c0_seq1 transcribed RNA sequence) HSP 1 Score: 114.775 bits (286), Expect = 1.808e-27 Identity = 59/156 (37.82%), Postives = 95/156 (60.90%), Query Frame = 0
Query: 102 KNFCAMTCHPQQSYFLQGQVMTSN-HFE------TQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESC-DVGVNGSEPCSCADCE-SACE 248
KNFC MTC QQ F++ + F+ T + V+++ +VTY+ +FV VY+SCK V P+VS T + ++CG+WG + C+P+RWF ++GS++NG+ PF+I+Y +S + + +G Q++N V C DV C C DC+ S+C+
Sbjct: 36 KNFCDMTCSNQQDQFIRADNLVEGPGFDNGYVNYTGQMVTMVKDVTYFAHTDFVTDVYESCKNVQFPAVSDTIMYMLCGEWGSEFCNPFRWFDFMGSVNNGYAPFKINYDYSNDLTSN---DGHQYHNPEVIPCNDVAPGYDRSCGCEDCQYSSCQ 494
BLAST of EMLSAG00000001950 vs. C. finmarchicus
Match: gi|592923571|gb|GAXK01034844.1| (TSA: Calanus finmarchicus comp110667_c1_seq5 transcribed RNA sequence) HSP 1 Score: 93.5893 bits (231), Expect = 2.483e-18 Identity = 83/293 (28.33%), Postives = 146/293 (49.83%), Query Frame = 0
Query: 576 SERSIEDEL-----AKETYGDISTIAV---------SYIIMFIYITFSLGENTTWKRFMVESKXXXXXXXXXXXXXXXAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQ---TCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCV--RGSKKNV--RQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYF 847
++ S DEL A ++GD+ST A+ YIIMFIY LG+ T +E ++ L + G+I V + + +IG+ + P T I I+PFL L +G D++F++VQ Q+DP A + + +G + S+ +TS+T+ F +GA++ MP + +F++ + L +L+QV+ F++ +SLD R ++ CV + K + +QN G+ VV K YA + + V++ G + + I D L +P DS++ ++
Sbjct: 1209 AQNSTRDELQVMVNAARSFGDVSTEAIFFDATLMAGGYIIMFIYTIVMLGKLNT-----LEVRLYLTISGIISVGMGLIIAIGLSSLLGYPYT-PIHAILPFLCLGIGIDDMFVIVQCWSNMQKDPLNAGLSLPDRMGIALKHAGVSVTVTSLTDVFAFGVGAVTQMPGLESFSVCTAIGLGSIYLLQVSWFVAWLSLDERRIATGRDGLLMCVVHKDYKPSTCCKQNLGDIVVKK-----YAKLLSSVIFKFLVIVFTLGMLGFGIWGSILIRQKFDPVLLLPSDSYLREWL 2054 HSP 2 Score: 45.8246 bits (107), Expect = 1.253e-3 Identity = 15/39 (38.46%), Postives = 31/39 (79.49%), Query Frame = 0
Query: 1206 NLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAF 1244
N++G ++FW+I+++ +S +N+V+A+G+ V++ HI AF
Sbjct: 471 NIIGFLHFWDITIDIISCINIVLAIGLCVDYSVHIGHAF 587
BLAST of EMLSAG00000001950 vs. L. salmonis peptides
Match: EMLSAP00000001950 (pep:novel supercontig:LSalAtl2s:LSalAtl2s1345:18618:29195:1 gene:EMLSAG00000001950 transcript:EMLSAT00000001950 description:"maker-LSalAtl2s1345-snap-gene-0.7") HSP 1 Score: 2701.01 bits (7000), Expect = 0.000e+0 Identity = 1303/1303 (100.00%), Postives = 1303/1303 (100.00%), Query Frame = 0
Query: 1 MYGFVLFIVGALLKVACGRXIWFENCSQSPYLENNADKWLNCAYDGEAKEAPLLKLERICPHLDPSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGVNGSEPCSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENGITLKDICHAPLEPISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAYYMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTIDDSCCKYRAVDMSVCQSNGESKAKAQSALSFIDKFFENDDFFGGNSVNDFDDYDHEEEEKEESNSSKNGVLPESMFSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTSHQSTQDGNDATKKTKNRIIAIKSGYFQMNSASTPYSFLVQPKTI 1303
MYGFVLFIVGALLKVACGRXIWFENCSQSPYLENNADKWLNCAYDGEAKEAPLLKLERICPHLDPSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGVNGSEPCSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENGITLKDICHAPLEPISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAYYMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTIDDSCCKYRAVDMSVCQSNGESKAKAQSALSFIDKFFENDDFFGGNSVNDFDDYDHEEEEKEESNSSKNGVLPESMFSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTSHQSTQDGNDATKKTKNRIIAIKSGYFQMNSASTPYSFLVQPKTI
Sbjct: 1 MYGFVLFIVGALLKVACGRXIWFENCSQSPYLENNADKWLNCAYDGEAKEAPLLKLERICPHLDPSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGVNGSEPCSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENGITLKDICHAPLEPISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAYYMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTIDDSCCKYRAVDMSVCQSNGESKAKAQSALSFIDKFFENDDFFGGNSVNDFDDYDHEEEEKEESNSSKNGVLPESMFSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTSHQSTQDGNDATKKTKNRIIAIKSGYFQMNSASTPYSFLVQPKTI 1303
BLAST of EMLSAG00000001950 vs. L. salmonis peptides
Match: EMLSAP00000008403 (pep:novel supercontig:LSalAtl2s:LSalAtl2s513:547002:563743:1 gene:EMLSAG00000008403 transcript:EMLSAT00000008403 description:"maker-LSalAtl2s513-augustus-gene-5.4") HSP 1 Score: 639.032 bits (1647), Expect = 0.000e+0 Identity = 338/654 (51.68%), Postives = 426/654 (65.14%), Query Frame = 0
Query: 197 TPFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGVNGSEPCSCADCESACEPPHFEETQVGF-YIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIE-----------------------------------------------NIKTKENGITLKDICHAPLEPISD-------------GGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAY---------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRG 774
TPFQID+VFSG+ + IPE + +YNT +E C++ VNG PCSC DCES+C + Y ++ + F MAIIF++G +IF+ +VI S+ +K S D +D+ GS ++ S+ ++N I+ AG DL+ WL+ FFT WGTFCA YP+PVI +S+ +A+GLCTGIFWL VTTDPIELWASP SRSR E+DFFD+TF PFYRI QVI+KAKNLS+F+Y+D GETK FGPIFHK EFL PLL LQK IE N KT N L P+S GGIP++PY++LGGF+ N NP YH+A+AVVI+ +INNY+ S +P+E++KL A+EWEK + +MDIAFTSERSI DE++KET GDI+TI +SY+IMF+YIT SLG+NT+ KRF++ESKITL +GGV+IV++SV AS+GIFGFID PATLIIFEIIPFLVLA GXDNIF++VQ QR +TETH E++GRIVG+V PSMLLTS TESTCFFLGAIS MPAVRAFALYAGMALLIDF MQ+TCFISL++LD+ARQ +N++DI +RG
Sbjct: 3 TPFQIDFVFSGD-KXASIPEEMSYYNTEIEPCNIRVNGKSPCSCTDCESSCASQIINDKNHHLEYNNYRLNISSFSMAIIFLIGFLIFVGVVITSRFIKEFSIRADCTDMNDT----------GSSKTFFSR--------------------TINSIKNAGEDLDEWLIIFFTRWGTFCATYPVPVIFLSVLMALGLCTGIFWLRVTTDPIELWASPQSRSRQEKDFFDETFGPFYRIAQVIIKAKNLSTFQYEDLFGETKEFGPIFHKYEFLLPLLRLQKEIEKIETQDNKVLLKDICHTPLTPTSNACNIQNLWSYWQDDPKELDKTGYNDKTNHNDTYLDHFILCSRNPVSQAAETSMKQSCMSKGGIPIKPYFVLGGFLSGNASDFTNPKYHQANAVVITFLINNYNQYSRDPQEMRKLHLAMEWEKTFIEFIHKWIQNPENTKHMDIAFTSERSIGDEISKETTGDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGIFGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTETHQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQRENFWDIFYWIRG 625 HSP 2 Score: 333.569 bits (854), Expect = 1.890e-96 Identity = 164/286 (57.34%), Postives = 210/286 (73.43%), Query Frame = 0
Query: 977 DHEEEEKEESN--SSKNGVLPESMFSKYDQFY-YYEDEDDNQNSVQTKKGRSKRATDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
++EEE EE + L S K+D ++ + +SV++K ++KR + C KCPNSDDA D + GP AFRRY+ WFLEDNPG CPKAGHAAYS+S+ +K D + F +Y+VIASNFMTFHTILK+ KDYYEALR +R+L+SEIEN+IN N+T+++Q +VFPYSIFYVFYEQYLTMW DTI SL +SF+SI IVTFI TGF+ ++S+II+V I MI NLMGMMY WNISLNA+SLVNLVMA+GIS+EFCSH K F H ++ R++ +
Sbjct: 646 NNEEETDEEIRFLKKREKYLMYSGDRKFDLYHPWTTGLSSMDDSVKSKNLKAKRELNICQKCPNSDDATDENKLGPMAFRRYLSWFLEDNPGVNCPKAGHAAYSKSLYIKKRAYLDQDGFTEYDVIASNFMTFHTILKSSKDYYEALRMSRQLASEIENAINRNVTNENQKARVFPYSIFYVFYEQYLTMWGDTIKSLCISFISIFIVTFIFTGFELISSLIILVTIVMITANLMGMMYLWNISLNAISLVNLVMAIGISIEFCSHSVKYFLHKEGVNRVQRSEIT 931
BLAST of EMLSAG00000001950 vs. L. salmonis peptides
Match: EMLSAP00000004370 (pep:novel supercontig:LSalAtl2s:LSalAtl2s22:157610:161978:1 gene:EMLSAG00000004370 transcript:EMLSAT00000004370 description:"maker-LSalAtl2s22-snap-gene-1.32") HSP 1 Score: 400.593 bits (1028), Expect = 2.193e-120 Identity = 236/650 (36.31%), Postives = 364/650 (56.00%), Query Frame = 0
Query: 362 WLV--NFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKN---LSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENGITLKDICHAPLEP-------------------------ISDGG----------------IPVQPYYMLG------GFIPENEPF----------PQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAY------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVE---HVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYK-----LFKHFYAPFVMKEW-VRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTIDDSCC 928
WL+ FF G FC+KY + V+I + I I L +G+FWL VT++PIELW+S +SRSR E DFF++ F PF+R + +I+ N L FKY++ G+ +F IF +E F + +L+LQK IE I T E+ ITL+D+C+ PL P +D G ++ +G GF+P F P++ + A ++++ N + ++K A++WEK++ +DIAF +E SI+D + ++GD+ + +SY +MF+Y++F+L + K F ITL + G+ +VL S+ ++ G+FGFI V AT+IIFEI+PFLVLAVG DNIF++V T +R +E +G + E+AP+ML++++T++ F+LG +S MPAV FALYAG +LLI+FL Q+T FI+++SLD+ R D+ CC+ + N Y+ F+ + +P +MK+ V+ +V+++ +L T I VGLD + +MP S+V KYF +++ Y SVGPPVYFVV+S+N+DL+ QN+ CG AGC S + + LWS +P+ T +A QSWIDDY +W+ D CC
Sbjct: 106 WLLFQTFFRKLGYFCSKYAVYVLICNGIIFIVLSSGVFWLKVTSEPIELWSSTNSRSRKEMDFFNEHFEPFFRTSILIIXPSNESFLQKFKYNNLYGKEATFSXIFRQEMF-YQVLKLQKEIEKIIT-EDKITLQDVCYKPLAPEIPSCLLQSVWNYWQGSNSSFNLNITNDRGHQDTYLDHLTTCVENPFTIKSSTAMGQSCLSKGFVPLEAKFVMGGFKTDKSPESLDSEDILANTSALIMTFLLQNHIEKDRVEK---AIKWEKSFVKWIESNLENFPLLDIAFIAEMSIQDAIESNSHGDVLVVIISYFLMFVYVSFALTDFRNKKYF----GITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKLTVKFSVMVLIAITLSITLVFTLNIPVGLDPESTMPKGSYVKKYFEWLKLYYSVGPPVYFVVNSTNMDLATVKSQNRICGSAGCDPYSFQTAMKLWSTKPDLTTLATSGQSWIDDYFSWSND--CC 744 HSP 2 Score: 94.7449 bits (234), Expect = 8.475e-20 Identity = 52/140 (37.14%), Postives = 84/140 (60.00%), Query Frame = 0
Query: 1098 VIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFC 1237
++ SNFM FHT+L+T D+ +A+ R LS + + + FPYSIF+V+YEQYL+M +DT+ S+ L++ ++ + L+G + + V ++ ILI++ G + I LNA+ VNL++A GISVE C
Sbjct: 754 ILFSNFMAFHTVLRTSNDFVQAIESTRILSDKFA---------RENNITSFPYSIFHVYYEQYLSMKTDTLVSIAYVLLTMLLICWFLSG-KIVIGLYTVTFVSSILIHVTGFISMLGIQLNAILAVNLLVACGISVEIC 883
BLAST of EMLSAG00000001950 vs. L. salmonis peptides
Match: EMLSAP00000002936 (pep:novel supercontig:LSalAtl2s:LSalAtl2s168:234565:235661:-1 gene:EMLSAG00000002936 transcript:EMLSAT00000002936 description:"maker-LSalAtl2s168-augustus-gene-2.28") HSP 1 Score: 153.68 bits (387), Expect = 1.920e-40 Identity = 94/282 (33.33%), Postives = 145/282 (51.42%), Query Frame = 0
Query: 18 GRXIWFENCSQSPYLENNADKWLNCAYDGEAKE--APLLKL-ERICPHLDP--SEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGVNG-SEPCSCADCESACEPPHFEETQVGFYI--VPGVDGTIFIMAIIFVVGXIIFLAIVIASK 291
G + C + P + L C +G E A L KL ++ CPH + S +CC+++Q+ ++ F I CPTC +N KK FC TCHP+QS FL V + EEV + + YY +FV VY+ CK V+ PS S + + +CG LC+P + Y+G+ S+ +PF+ID+ +S + IP ++Y+ +CDV G S PCSC +CE +C F + Q +I + G+DG +M +IF V + FL +++ K
Sbjct: 22 GHCVLRGICGKDPTVTVGKIPKLLCVDEGPPTEMDASLKKLMKKACPHFESEISSNICCTKEQIRDLKSQFKSLDLIASHCPTCTYNMKKVFCDFTCHPEQSKFLNVSVKIWGPNDKGEEVEMAKVLQYYANIDFVNSVYNGCKDVLFPSQSISIMGFICGT-APTLCTPKKLLNYMGTPSSITSPFKIDFKYSDDPPE--IPHKFEYYSPNTLTCDVPPPGESVPCSCTNCELSCSQIDFGKYQTSSFIFYIGGIDGLSIVMGVIFSVFTVAFLFVLVQQK 300
BLAST of EMLSAG00000001950 vs. L. salmonis peptides
Match: EMLSAP00000008727 (pep:novel supercontig:LSalAtl2s:LSalAtl2s542:206164:232722:1 gene:EMLSAG00000008727 transcript:EMLSAT00000008727 description:"maker-LSalAtl2s542-augustus-gene-2.8") HSP 1 Score: 93.9745 bits (232), Expect = 1.425e-19 Identity = 130/586 (22.18%), Postives = 232/586 (39.59%), Query Frame = 0
Query: 371 GTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFY------------RITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPL------------------------------LELQKNIENIKTKENGITLKDICHAPL--EPISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAY----------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIM--FIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCV-----RGSKKNV-----------------RQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQN 878
G K+P +I+ L + TG L+ +DP L++ S ER + F Y R ++I+ +K+ S E +S + E +F L L+L K+I I++KE +T PL +P + G + GG I N+ + +AV + +N+ + K +E+ +WE + Y+ +A S ++E EL T I A++ IM F IT + T W V+SK LGL GVI +++ S G + VP I PFL+L +G D+ F+M+ + +R ET + + + A S+ +TS+T+ F++G I+ P+VR F LY G + +L +T F +++ + N + + C + KN +++ E + +F+ + A + + + V++ F + + I+ GL++K DS+ ++++ + Y P VV S + + S +QN
Sbjct: 21 GIIVGKHPGYFVIIPLLLTALAATGFQRLHFQSDPEYLFSPSDGESHYERKVLETYFNTNYSDFEPSRSSRVGRFGKLIISSKDNGSILRMKIWEEIESLNFLIENFE-VFSLKECDEVKSSMKLNFKDLCASHQGKCWRNKILDLGKHITEIESKEIKLTF------PLWFDPETFQGYTFN--FFFGGVILRNDS-----TIKSVTAVSLFYFLNS--------QTSKDIERGAKWEGMFLATVEAQSFSYIKVARFSSLTLEVELENNTNSVIPFFALNIGIMIAFCIITCMM---TDW----VKSKPLLGLFGVISAIMAXLFSFGFIIYCGVPFIGINLAA-PFLMLGIGIDDTFVMLGSWRRT--SVHETVPARLAQTYRDAAISITITSITDMLSFWIGIITPFPSVRIFCLYTGACVAFTYLWHITFFGGCMAIAGYAEKSNRHSLTCLTVIPKSKAESKNWLYRIFCSGGISPDDPFNKKDNAENAIMVIFRDYVARAINNGYFKIFVLVFFTFYLVIAGWGVSNIQEGLERKKLARYDSYSVEFYEMEDTYFREYPYRVNVVLSGHFNYSNLQVQN 574
BLAST of EMLSAG00000001950 vs. L. salmonis peptides
Match: EMLSAP00000007725 (pep:novel supercontig:LSalAtl2s:LSalAtl2s44:25674:28922:-1 gene:EMLSAG00000007725 transcript:EMLSAT00000007725 description:"maker-LSalAtl2s44-augustus-gene-0.13") HSP 1 Score: 93.9745 bits (232), Expect = 1.740e-19 Identity = 79/310 (25.48%), Postives = 142/310 (45.81%), Query Frame = 0
Query: 578 RSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGI---FGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQR-DPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGE----------GVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSL 873
RS D GD+ + + Y I+F Y+ LG+ W V + L + G+I V+ + SIGI GF P + I+PFL+L +G D++FI++Q +P + V+ G + ++ +TS+T+ F +G S +PA+R+F +++ + + + QVT F++ + D R + CC K V++N E ++ K+F+ FYA + + V+ +++I G+ IE D +P +++ +F K+ S + V VDLS+
Sbjct: 382 RSFFDIAGPTILGDVKILGIGYSIVFFYVLLMLGK-FDW----VGXRXYLAIAGIISVVFGIVFSIGICSAMGFFWSP----MHSILPFLLLGIGIDDMFIIIQCWNTLNPYEKASSSVDKFGYTMRHAGVAITVTSLTDIVAFGIGGTSXLPALRSFCIFSAVGIAAIYYFQVTFFVAWMVFDEKRISSGRNG--CCPCIEVKKVKKNTEEIMEDMEVESLSIMSKIFR-FYASHLKFKPVKFLIILITMGFTSLGAYGNYLIEQKFDPIWFIPPHTYLSDWFEANTKWFSDKGGFFVNVYVYEVDLSV 679 HSP 2 Score: 56.9954 bits (136), Expect = 3.419e-8 Identity = 30/128 (23.44%), Postives = 77/128 (60.16%), Query Frame = 0
Query: 1135 NGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSME---ETKILRAKTS 1259
+ NLT ++FP S Y +E + + +++ +F+++ I+T+I+ +F+ S +++ + + ++++ G+M+FW ++++ VS L++++G+ V++ +H+A F E + +I++A T+
Sbjct: 797 SANLTSSG---RIFPLSQGYSMWETDEIIGYELYKNIIFAFVAVFIMTWIVIS-NFVASFLVLFAVMLTVLDVSGIMHFWGLTIDTVSCNFLIISIGLCVDYSTHVAHRFLIEAEGSRDQRIVKALTN 920
BLAST of EMLSAG00000001950 vs. L. salmonis peptides
Match: EMLSAP00000003602 (pep:novel supercontig:LSalAtl2s:LSalAtl2s197:152115:159124:1 gene:EMLSAG00000003602 transcript:EMLSAT00000003602 description:"maker-LSalAtl2s197-snap-gene-1.29") HSP 1 Score: 93.5893 bits (231), Expect = 2.137e-19 Identity = 77/302 (25.50%), Postives = 143/302 (47.35%), Query Frame = 0
Query: 488 ITLKDICHAPLEPISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAYY--------MDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTC----QRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYD--IICCVRGS 775
+T +DI A + ++ + +P+ + G ++ F N + A A+++S I NS + I EK+++ Y + + S E D+ Y+I+F+YI F+LGE T +E K L + G+ V + A+S+GIF + V AT + I+PF++L +G D++F++VQ Q D ++G I+ ++ +TS+T+ F +G S +PA+R F LY+ + + +T F+ +D AR+ +++ D + C ++ S
Sbjct: 186 LTDEDILDALSQDLAISKLFRRPFRPIIG----SKMFNDNGTLKGAKALLLSYSIKT---NSSDKNGIPIWEKSVKEHVFNYSFGDESSNLSVTLFSSSIFRAEFQNGMENDVQLFIFGYLIVFVYIIFNLGEMNT-----LEHKFYLAVVGIACVGMGYASSVGIFQLLSVYATPM-NSILPFMLLGIGIDDMFVIVQASKNVKQNDDEEGENKMDSYIGNIMKSAGXAITVTSLTDILAFGIGGFSQLPALRNFCLYSSAGIFFVYFYIMTFFLGWFVID-ARRVESHRDACLPCIIKKS 473 HSP 2 Score: 56.225 bits (134), Expect = 4.929e-8 Identity = 40/157 (25.48%), Postives = 84/157 (53.50%), Query Frame = 0
Query: 1104 MTFHTILKTP-KDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
+ F I KT +D ++++ ++ +IE NG +FP++ Y + S+ ++L++ +++ I L LTSI +++ I + +I++ G MYFW +S++ S V L +++G++V++ +HIA + HS + ++ + K S
Sbjct: 651 LYFQHIKKTRVQDQIQSMKKIYQIGEKIEGERNG---------LIFPHATQYSNLITLDIILSELTRNILLALMTVFIAALFLLAXA-LTSIYVLLSILLSIIDVTGYMYFWGVSIDTASAVLLTVSLGLAVDYSAHIAHGYIHSSKSSRGEKVKDS 797
BLAST of EMLSAG00000001950 vs. L. salmonis peptides
Match: EMLSAP00000010537 (pep:novel supercontig:LSalAtl2s:LSalAtl2s6:1415448:1420769:-1 gene:EMLSAG00000010537 transcript:EMLSAT00000010537 description:"maker-LSalAtl2s6-augustus-gene-13.12") HSP 1 Score: 78.9518 bits (193), Expect = 6.094e-15 Identity = 64/288 (22.22%), Postives = 134/288 (46.53%), Query Frame = 0
Query: 593 STIAVSYIIMFIYITFS-LGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQN----------GG---------------EGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYL 854
ST+ ++ +IM ++ S L + T +SK +G G+ ++ A G ++ V + F PFL+L +G D+ F+++ + +R + + E +GR E A S+ +TS+T+ F G ++ P VR F LY G+++ + +T F +++++ + +N + + C ++ K++ N GG G+V+ F+ + + W ++ V+++F + + IE GL+++ DS+ +KY++ + Y
Sbjct: 274 STLCINVVIMVVFSLVSCLMSDAT------KSKPLVGFAGLFSATIATIAGFGFACYVGVEFISLNFAA-PFLLLGIGVDDTFVILSSWRRS--SSNLSIPERMGRCYSEAAVSITVTSLTDFFSFMAGVVTPFPCVRIFCLYTGISVAFIYFWHLTLFGAILAVSGRAEKNNLHGMFC-IKVIPKSLAVNKSWLTRTFMTGGTNPKDPHNPDDNKDHAGMVF--FRDNMGRLLSRTWFKSLVLLLFGAYIVVACWGVTNIEEGLEKQNMANYDSYSVKYYSMDDSYF 549 HSP 2 Score: 61.6178 bits (148), Expect = 1.274e-9 Identity = 35/131 (26.72%), Postives = 70/131 (53.44%), Query Frame = 0
Query: 1126 LSSEIENSINGNLTD-----KSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEET 1251
L+S +E S+ L D + + + + ++++ +QYL + T+ +LV+ L + I++F L + S + I I + ++G M +W + L+ V+L+NL+M +G SV+F +HI + E +
Sbjct: 670 LNSYMEQSMVAELRDICNQFSTPDISISVFHPYFIYIDQYLAIAPQTVQCILVTSLVMMIISFFLIP-SLVCSFWVAFSIISIELGVIGYMTWWGVRLDGVALINLIMCIGFSVDFSAHICYHYITDTESS 799
BLAST of EMLSAG00000001950 vs. L. salmonis peptides
Match: EMLSAP00000012098 (pep:novel supercontig:LSalAtl2s:LSalAtl2s867:155984:163315:1 gene:EMLSAG00000012098 transcript:EMLSAT00000012098 description:"maker-LSalAtl2s867-snap-gene-0.32") HSP 1 Score: 69.3218 bits (168), Expect = 5.891e-12 Identity = 110/542 (20.30%), Postives = 228/542 (42.07%), Query Frame = 0
Query: 371 GTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNI-ENIK-TKENGITLKDIC-HAPLEPISDGGIPVQPYY--MLGGFIPENEPFPQNPSYHEASAVVI---SIMINNYDHNSPNPEEIKKLEKALEWEKAYYMDIAFT-------------------SERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLG-AISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYA---PFVMKEWVRAAVVIIFFGWFCTS--LAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNK 879
G F K+P I V + + +G+ + +DP L+ SR+ +++ +K F Y ++ K LS+ +Y+ L G E+ + EL K I E ++ ++ +T KDIC + + + + ++ + + G + P Q+P+ +E + I I ++ + N + +L L+ ++ Y ++ + + +SIE E A I + +S ++ I++++ W ++ K + L G + +++++ A+ G +I V I + F++L VG D+I++++ + +R + E + E A S+ +TS+T F +G A P+V F LY+G+ + ++ +T F ++++ + R KK + + HFY P ++ + +VI + + TS L + + GLD+ DSF+ Y+ + Y P + VV + +D S ++ +
Sbjct: 23 GRFIGKHPSHFITVPFLLGLLFASGLQQIVYQSDPKYLFFPSYSRTINDKEIVEKLFPTNYSNYEI---GKELSN-EYEAHLIFVPKNGSSLLNIEYWKSIAELDKIIYEKLRIVQDKNVTFKDICVKFEGQCVRNTFLSLRRFMKEINSGLLELTYPMTQDPTTYEIYKLPIFAGGITVDENNTNIVRKIQALRLSYILDPSQSKYANLWLSALLEFLDNISTPHLNVYKMTTKSIEVEFASNVDSAIDFLPLSVALL---ISYNIWNALNWNNPIL-GKPYVSLVGSLNIVVAIGAAWGFLMYIGVEWISINLASV-FILLGVGLDDIYVILFSWRRTSELLSVP--ERLSLCYEEAAVSITITSLTNIVSFVMGSAFPVFPSVWIFCLYSGIGIFFIYIWTLTFFGGVLAISGYTEETE--------RLKKKQDIDIVDSEIGFDFLNHFYESTLPNILNKVYAKVIVIALYLTYLTSFILIILNNTKEGLDRSKLSRYDSFLSSYYKAEDNYFRQNPYRFQVVFTEALDYSNSSVRQQ 545
BLAST of EMLSAG00000001950 vs. L. salmonis peptides
Match: EMLSAP00000005221 (pep:novel supercontig:LSalAtl2s:LSalAtl2s276:209809:212602:-1 gene:EMLSAG00000005221 transcript:EMLSAT00000005221 description:"maker-LSalAtl2s276-augustus-gene-2.14") HSP 1 Score: 65.855 bits (159), Expect = 5.811e-11 Identity = 46/181 (25.41%), Postives = 92/181 (50.83%), Query Frame = 0
Query: 581 EDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHV-EHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMAR 760
+DE+ G + V ++++ IY SL + + V ++ L L G +++ +++ +S G+ GF + IIPFL+L +G D++FI++++ + E + E + +V S+ +TS+T+ F + + + +P +RAF L + + + VT FI+ +LD R
Sbjct: 30 QDEIVTSIDGGMYVFGVGFLLILIY---SLLVTSDFHP--VNQRVMLLLLGFMVIGMAIGSSFGL-GFHIGIIYADLHPIIPFLLLGIGVDDLFIIIKSTDNLSQKEKELPLKERIALVVQHSGVSITVTSLTDLVAFLISSTTSIPLLRAFCLSVALGISFLYFFVVTFFIAWYTLDERR 204
BLAST of EMLSAG00000001950 vs. SwissProt
Match: gi|1100165154|sp|Q9VRC9.2|NPC1B_DROME (RecName: Full=Niemann-Pick type protein homolog 1B; Flags: Precursor) HSP 1 Score: 440.269 bits (1131), Expect = 6.304e-132 Identity = 244/652 (37.42%), Postives = 372/652 (57.06%), Query Frame = 0
Query: 367 FTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNI-----------------------------------------------ENIKTKENGIT------LKDICHAPLEPISDG--GIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAYY----------MDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGV--------VYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTIDDSCCKYRAVDMSVCQSNGESK 945
F WGTFCAK+P+ V+ + GL GI ++ +TTDP+ELWA S++R+E+D+FD+ F PFYR Q+ VKA N + F ++ G +FGP F + FL + ELQ +I EN N T L+D P+ G G P++P +GG +P+ ++P Y A+ +V++ + NY+ S KLE ++WEK + +DIA+ +ERSI+D + + + G++ST+ +SY++MF+Y+ +LG + + F+ ES+I L +GG++IVL SV S+G +G++DV T++ E+IPFLVLAVG DNIFIMV T QR +T E +G +G+V PS+L T+ +E CF +G ISDMPAV+ FA+YA +A+L+DFL+Q+T F++L+++D R D D++CCV+ K + G+GV + LFK+FY+PF++ + V+ +V++IF C SL VTP IE GLDQ++SMP +S V+KYF ++ L++G PVY+V+ ++ S P QN CGG C++ SL+ + ++ PE T +A PA SW+DDY+ W CCKY C SN +S+
Sbjct: 314 FRIWGTFCAKHPVIVLALCSWAIAGLSFGIRYMTITTDPVELWAGEESQTRIEKDYFDQHFGPFYRTNQMFVKAVNQTYFTHETSNG-VLNFGPAF-EYNFLKEVFELQDSIMKLGMADNEGLDKICYAPVLMAGETPTVDRCAIQSVYGYFQHDMDRFENSYVDSNNYTINYLNQLEDCLRVPMMEDCFGTFGGPIEPGIAVGG-MPK-VAVGEDPDYMLATGLVLTFLGRNYNDES-------KLEPNMKWEKLFVDFLRDYKSDRLDIAYMAERSIQDAIVELSEGEVSTVVISYVVMFVYVAIALGHIRSCRGFLRESRIMLAIGGIVIVLASVVCSLGFWGYLDVTTTMLAIEVIPFLVLAVGVDNIFIMVHTYQRLDHSKFKTTHEAIGEAIGQVGPSILQTAGSEMACFAIGCISDMPAVKTFAMYAAIAILLDFLLQITAFVALMAIDEKRYLDGRLDMLCCVKSGGKKINDEDGDGVDRPKEVGLLETLFKNFYSPFLLSKPVKVSVLLIFTVITCLSLMVTPSIEKGLDQEMSMPKNSHVVKYFRYMVDLLAMGAPVYWVL-KPGLNYSEPLQQNLICGGVECNNNSLSVQLYTQAQYPEITSLARPASSWLDDYIDWLAISDCCKYNVTTGGFCSSNSKSE 953 HSP 2 Score: 162.155 bits (409), Expect = 5.622e-39 Identity = 90/239 (37.66%), Postives = 137/239 (57.32%), Query Frame = 0
Query: 1025 SKRATDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTSHQST 1263
S ++ C+ C L RP + F +Y+ +FL D P C KAG A+Y+ +V + V S FM + T T +++Y LR RR+S EI N D ++F Y +FY++YEQYLT+W D + SL +S ++I +VT ++TG D ++ I++ ++ ILIN++GMM+ W+I+LNA+SLVNLV+ VGI VEF +HI ++F + E T RA+ S T
Sbjct: 948 SNSKSEDCLPCERGFTENGL-RPDAETFNKYIPYFLFDLPDAECAKAGRASYADAVIYTI------DDVGMSTVQDSYFMQYSTTSTTSEEFYSQLREVRRISGEINAMFKENNVD----AEIFAYCVFYIYYEQYLTIWGDAMFSLGMSLVAIFLVTLLITGLDITSTFIVLFMVICILINMLGMMWAWSINLNAISLVNLVVCVGIGVEFVAHIVRSFKRA-EGTAQERARHSLNVT 1174 HSP 3 Score: 112.849 bits (281), Expect = 8.170e-24 Identity = 64/239 (26.78%), Postives = 104/239 (43.51%), Query Frame = 0
Query: 48 AKEAPLLKLERICPHLDPSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQ--FYNTVVESCDVGVNGSEPCSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFL 284
AK P+L E + +CC Q++ ME + + + RCPTC N CAMTC + FL T+ + V + + Y + D+ V ++Y+SC + A+ L CG + K C+ RW+ ++G +S + PFQI+Y +S + EG + + C S C+C DCE +C + + G+ G FI+A+I F+
Sbjct: 59 AKRCPMLYKEYKGESGEDELSLCCDAAQIETMESGLSQADGVFSRCPTCTRNMALTVCAMTCAKNHTLFL-----TAYNDTNDAGVDYVKYIDYRLTDDTVSKIYNSCIGIQHTQTGRPAMDLGCGSYNAKTCNYRRWYEFMGDVSGDYVPFQINYKWSEDAE-----EGSNEIYLDLSPLKCGESYEDSYACACIDCEESCPLTDAPTGPDELWKIAGLYGVTFILALIIACALSFFI 287
BLAST of EMLSAG00000001950 vs. SwissProt
Match: gi|8134591|sp|P56941.1|NPC1_PIG (RecName: Full=Niemann-Pick C1 protein; Flags: Precursor) HSP 1 Score: 404.06 bits (1037), Expect = 9.889e-119 Identity = 206/442 (46.61%), Postives = 293/442 (66.29%), Query Frame = 0
Query: 505 GIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAYY----------MDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTI-DDSCCK-YRAVD 934
G PV P+ +LGG+ +N Y+ A+A+VI+ +NNY +++ +KL++A WE + + I+F +ERSIEDEL +E+ D+ TI +SY IMF+YI+ +LG + R +V+SKI+LG+ G++IVL SVA S+GIF +I VP TLI+ E+IPFLVLAVG DNIFI+VQT QRD R ET + +GR++GEVAPSM L+S +E+ FFLG +S +PAV F+L+AGMA+LIDFL+Q+TCF+SL+ LD+ RQ N D++CCV+G++ E +++ FK+ YAP ++K+W+R V+ +F G S+AV ++E+GLDQ LSMPDDS+V+ YF + +YL GPPVYFVV+ + SL G QN CGG GC+++SL I ++ T I SWIDDY W SCC+ Y + D
Sbjct: 538 GGPVFPWLVLGGYDDQN--------YNNATALVITFPVNNYYNDT------EKLQRAQAWESEFINFVKNYKNPNLTISFMAERSIEDELNRESNSDLFTILISYAIMFLYISIALGHIKSCSRLLVDSKISLGIAGILIVLSSVACSLGIFSYIGVPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLGGLSVVPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNRLDVVCCVQGAEDGAGVQASESCLFRFFKNSYAPLLLKDWMRPIVIAVFVGVLSFSIAVLNKVEIGLDQSLSMPDDSYVMDYFQSLSRYLHAGPPVYFVVEEGHNYTSLKG-QNMVCGGLGCNNDSLVQQIFTAAQLDNYTRIGFAPSSWIDDYFDWIKPQSSCCRVYNSTD 964 HSP 2 Score: 224.172 bits (570), Expect = 3.179e-58 Identity = 145/490 (29.59%), Postives = 230/490 (46.94%), Query Frame = 0
Query: 21 IWFENCSQSPYLENNADKWLNCAYDGEAKEAP---LLKLERICP-HLDPSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFE--TQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGVNG-SEPCSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDF-LGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENG--ITLKDICHAPLEP 500
+W+ C + + DK NC Y G K P ++ +CP + +CC +QL ++ N + L RCP+C +N FC +TC P+QS FL T ++ + T + + + + YYV + F +Y++C+ V PS + AL L+CG+ + C+ W Y+ + NG PF I +FS H G++ N + CD V+ + PCSC DC C P + + G+D IM ++ I+F A + + + + TP+ N + +S KG L GA E L F WG FC ++P V+ SL+ + +G+ ++ VTTDP++LW++P S++R E+++FD F PF+R+ Q+I++A N S Y + G FGP + + L +L+LQ IENI N +TL+DIC APL P
Sbjct: 26 VWYGECGIA-----SGDKRYNCRYSGPPKPLPEDGYDLVQELCPGFFFGNVSLCCDVQQLRTLKDNLQLPLQFLSRCPSCFYNLMNLFCELTCSPRQSQFLN-VTATEDYVDPVTNQTKTNVKELEYYVGETFANAMYNACRDVEAPSSNEKALGLLCGREA-QACNATNWIEYMFNKDNGQAPFTITPIFSDLPTH-----GMEPMNNATKGCDESVDEVTGPCSCQDCSIVCGPKPQPPPPPVPWRILGLDAMYVIMWSSYMAFLIVFFGAFFAVWCYRKRY----------FVSEYTPIDGNIAFSVNSSD------------KGQAFCCDPL------GAAFERGLRRLFAQWGAFCVRHPGCVVFFSLAFIVACSSGLVFIRVTTDPVDLWSAPGSQARREKEYFDTHFGPFFRMEQLIIRATNNQSHIYHPYPAGADVPFGPPLSR-DILHQVLDLQTAIENITASYNNETVTLQDICLAPLSP 474 HSP 3 Score: 194.126 bits (492), Expect = 7.311e-49 Identity = 102/230 (44.35%), Postives = 151/230 (65.65%), Query Frame = 0
Query: 1031 SCIKC-PNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
+CI+C P + + +RP + F R++ FL DNP +C K GHAAYS +V + + V A+ FMT+HT+L+ D+ +A++ AR ++S I ++ ++ +VFPYS+FYVFYEQYLT+ DTI +L VS +I +VT +L G + ++I+ V IAMIL+N+ G+M+ W ISLNAVSLVNLVM+ GISVEFCSHI +AFT S + +++ RA+ +
Sbjct: 975 TCIRCRPLTSEG--KQRPQGEDFMRFLPMFLSDNPNPKCGKGGHAAYSSAVNILGNGS---------GVGATYFMTYHTVLQASADFIDAMQKARLIASNITRTMG----LEASSYRVFPYSVFYVFYEQYLTVIDDTIFNLGVSLGAIFLVTVVLMGCELWATVIMCVTIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTLSTKGSRVDRAEEA 1189
BLAST of EMLSAG00000001950 vs. SwissProt
Match: gi|449081276|sp|O35604.2|NPC1_MOUSE (RecName: Full=Niemann-Pick C1 protein; Flags: Precursor) HSP 1 Score: 403.675 bits (1036), Expect = 1.268e-118 Identity = 203/460 (44.13%), Postives = 302/460 (65.65%), Query Frame = 0
Query: 493 ICHAPLEPISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAYY----------MDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAW-TIDDSCCKYRAVDMSVCQSN 941
+ H P + G PV P+ +LGG+ +N Y+ A+A+VI+ +NNY +++ ++L++A WEK + + I+FT+ERSIEDEL +E+ D+ T+ +SY++MF+YI+ +LG + R +V+SKI+LG+ G++IVL SVA S+GIF ++ +P TLI+ E+IPFLVLAVG DNIFI+VQT QRD R ET + +GRI+GEVAP+M L+S +E++ FF GA+S MPAV F+L+AGMA+LIDFL+Q+TCF+SL+ LD+ RQ N+ DI+CCVRG+ + E +++ FK+++AP ++K+W+R VV +F G S+AV ++++GLDQ LSMP+DS+V+ YF + +YL GPPVYFV++ S G QN CGG GC ++SL I ++ T + SWIDDY W + SCC+ V C ++
Sbjct: 528 LLHGPC--LGTFGGPVFPWLVLGGYDDQN--------YNNATALVITFPVNNYYNDT------ERLQRAWAWEKEFISFVKNYKNPNLTISFTAERSIEDELNRESNSDVFTVIISYVVMFLYISLALGHIQSCSRLLVDSKISLGIAGILIVLSSVACSLGIFSYMGMPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFGALSSMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNHLDILCCVRGADDGQGSHASESYLFRFFKNYFAPLLLKDWLRPIVVAVFVGVLSFSVAVVNKVDIGLDQSLSMPNDSYVIDYFKSLAQYLHSGPPVYFVLEEGYNYSSRKG-QNMVCGGMGCDNDSLVQQIFNAAELDTYTRVGFAPSSWIDDYFDWVSPQSSCCRLYNVTHQFCNAS 970 HSP 2 Score: 224.557 bits (571), Expect = 2.386e-58 Identity = 151/492 (30.69%), Postives = 236/492 (47.97%), Query Frame = 0
Query: 21 IWFENCSQSPYLENNADKWLNCAYDGEAKEAPLLK-----LERICPHLD-PSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFE--TQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGVNG-SEPCSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDF-LGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENG--ITLKDICHAPLEP 500
+W+ C + DK NC Y G K PL K ++ +CP L + +CC +QL ++ N + L RCP+C +N FC +TC P QS FL T ++F+ TQE + + + Y+V F +Y++C+ V PS + AL L+CG+ + C+ W Y+ + NG PF I VFS + G++ + C+ V+ + PCSC DC C P + + G+D IM + +V +F ++A + + F + + TP+ N + +S KG L GA + L FT WG FC + P +I SL+ +G+ ++ VTT+P+ELW++P S++R+E+++FDK F PF+R Q+I++A N S Y+ + G FGP +K E L +L+LQ IE+I N +TL+DIC APL P
Sbjct: 26 VWYGECGIA-----TGDKRYNCKYSGPPK--PLPKDGYDLVQELCPGLFFDNVSLCCDIQQLQTLKSNLQLPLQFLSRCPSCFYNLMTLFCELTCSPHQSQFLN-VTATEDYFDPKTQENKTNVKELEYFVGQSFANAMYNACRDVEAPSSNEKALGLLCGR-DARACNATNWIEYMFNKDNGQAPFTIIPVFSDLSI-----LGMEPMRNATKGCNESVDEVTGPCSCQDCSIVCGPKPQPPPPPMPWRIWGLDAMYVIMWVTYVAFLFVFFGALLA--VWCHRRRYF--------VSEYTPIDSNIAFSVNSSD------------KGEASCCDPL------GAAFDDCLRRMFTKWGAFCVRNPTCIIFFSLAFITVCSSGLVFVQVTTNPVELWSAPHSQARLEKEYFDKHFGPFFRTEQLIIQAPNTSVHIYEPYPAGADVPFGPPLNK-EILHQVLDLQIAIESITASYNNETVTLQDICVAPLSP 474 HSP 3 Score: 198.749 bits (504), Expect = 3.376e-50 Identity = 103/230 (44.78%), Postives = 154/230 (66.96%), Query Frame = 0
Query: 1031 SCIKC-PNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
+C++C P + + +RP K F +++ FL DNP +C K GHAAY +V + ++++ + A+ FMT+HTILKT DY +A++ AR ++S I ++ K +VFPYS+FYVFYEQYLT+ DTI +L VS SI +VT ++ G + +++I+ + IAMIL+N+ G+M+ W ISLNAVSLVNLVM+ GISVEFCSHI +AFT S + +++ RA+ +
Sbjct: 975 TCVRCRPLTPEG--KQRPQGKEFMKFLPMFLSDNPNPKCGKGGHAAYGSAVNIVG-----DDTY----IGATYFMTYHTILKTSADYTDAMKKARLIASNITETMR----SKGSDYRVFPYSVFYVFYEQYLTIIDDTIFNLSVSLGSIFLVTLVVLGCELWSAVIMCITIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTMSTKGSRVSRAEEA 1189
BLAST of EMLSAG00000001950 vs. SwissProt
Match: gi|83305902|sp|O15118.2|NPC1_HUMAN (RecName: Full=Niemann-Pick C1 protein; Flags: Precursor) HSP 1 Score: 400.593 bits (1028), Expect = 2.037e-117 Identity = 201/448 (44.87%), Postives = 294/448 (65.62%), Query Frame = 0
Query: 505 GIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAYY----------MDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTI-DDSCCKYRAVDMSVCQSN 941
G PV P+ +LGG+ +N Y+ A+A+VI+ +NNY +++ +KL++A WEK + + I+FT+ERSIEDEL +E+ D+ T+ +SY IMF+YI+ +LG + +R +V+SK++LG+ G++IVL SVA S+G+F +I +P TLI+ E+IPFLVLAVG DNIFI+VQ QRD R ET + +GR++GEVAPSM L+S +E+ FFLGA+S MPAV F+L+AG+A+ IDFL+Q+TCF+SL+ LD+ RQ N DI CCVRG++ E +++ FK+ Y+P ++K+W+R V+ IF G S+AV ++++GLDQ LSMPDDS+++ YF I +YL GPPVYFV++ + S G QN CGG GC+++SL I ++ T I SWIDDY W SCC+ + C ++
Sbjct: 538 GGPVFPWLVLGGYDDQN--------YNNATALVITFPVNNYYNDT------EKLQRAQAWEKEFINFVKNYKNPNLTISFTAERSIEDELNRESDSDVFTVVISYAIMFLYISLALGHMKSCRRLLVDSKVSLGIAGILIVLSSVACSLGVFSYIGLPLTLIVIEVIPFLVLAVGVDNIFILVQAYQRDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLGALSVMPAVHTFSLFAGLAVFIDFLLQITCFVSLLGLDIKRQEKNRLDIFCCVRGAEDGTSVQASESCLFRFFKNSYSPLLLKDWMRPIVIAIFVGVLSFSIAVLNKVDIGLDQSLSMPDDSYMVDYFKSISQYLHAGPPVYFVLEEGHDYTSSKG-QNMVCGGMGCNNDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQSSCCRVDNITDQFCNAS 970 HSP 2 Score: 219.164 bits (557), Expect = 1.279e-56 Identity = 147/492 (29.88%), Postives = 227/492 (46.14%), Query Frame = 0
Query: 21 IWFENCSQSPYLENNADKWLNCAYDGEAKEAPLLK-----LERICP-HLDPSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFE--TQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGVNG-SEPCSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDF-LGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENG--ITLKDICHAPLEP 500
+W+ C + DK NC Y G K PL K ++ +CP + +CC +QL ++ N + L RCP+C +N FC +TC P+QS FL T ++ + T + + + + YYV F +Y++C+ V PS + AL L+CGK D C+ W Y+ + NG PF I VFS H G++ N + CD V+ + PCSC DC C P + + G+D IM I ++ ++F A + + + + TP+ N + S + S V A E L FT WG+FC + P VI SL +G+ ++ VTT+P++LW++PSS++R+E+++FD+ F PF+R Q+I++A Y + G FGP + L +L+LQ IENI + +TL+DIC APL P
Sbjct: 26 VWYGECGIA-----YGDKRYNCEYSGPPK--PLPKDGYDLVQELCPGFFFGNVSLCCDVRQLQTLKDNLQLPLQFLSRCPSCFYNLLNLFCELTCSPRQSQFLN-VTATEDYVDPVTNQTKTNVKELQYYVGQSFANAMYNACRDVEAPSSNDKALGLLCGKDADA-CNATNWIEYMFNKDNGQAPFTITPVFSDFPVH-----GMEPMNNATKGCDESVDEVTAPCSCQDCSIVCGPKPQPPPPPAPWTILGLDAMYVIMWITYMAFLLVFFGAFFAVWCYRKRY----------FVSEYTPIDSNIAFSVNASDKGEASCCDPVSAA------------------FEGCLRRLFTRWGSFCVRNPGCVIFFSLVFITACSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIRAPLTDKHIYQPYPSGADVPFGPPLDI-QILHQVLDLQIAIENITASYDNETVTLQDICLAPLSP 474 HSP 3 Score: 199.134 bits (505), Expect = 2.437e-50 Identity = 112/296 (37.84%), Postives = 171/296 (57.77%), Query Frame = 0
Query: 966 GGNSVNDFDDYDHEEEEKEESNSSKNGVLPESMFSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKC-PNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVR-LKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
GG N+ + N ++ G P S Y + + +++ + + +C++C P + + +RP F R++ FL DNP +C K GHAAYS +V L H + V A+ FMT+HT+L+T D+ +AL+ AR ++S + ++ N +VFPYS+FYVFYEQYLT+ DTI +L VS +I +VT +L G + +++I+ IAM+L+N+ G+M+ W ISLNAVSLVNLVM+ GISVEFCSHI +AFT SM+ +++ RA+ +
Sbjct: 910 GGMGCNNDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQSSCCRVDNITDQFCNASVVDPACVRCRPLTPEG--KQRPQGGDFMRFLPMFLSDNPNPKCGKGGHAAYSSAVNILLGHGTR---------VGATYFMTYHTVLQTSADFIDALKKARLIASNVTETMGIN----GSAYRVFPYSVFYVFYEQYLTIIDDTIFNLGVSLGAIFLVTMVLLGCELWSAVIMCATIAMVLVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRVERAEEA 1190
BLAST of EMLSAG00000001950 vs. SwissProt
Match: gi|73921247|sp|Q6T3U3.1|NPCL1_RAT (RecName: Full=Niemann-Pick C1-like protein 1; Flags: Precursor) HSP 1 Score: 378.252 bits (970), Expect = 3.548e-109 Identity = 191/450 (42.44%), Postives = 284/450 (63.11%), Query Frame = 0
Query: 488 ITLKDICHAPLEPISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAYY-------MDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAW-TIDDSCCK 929
+T KD L ++D G PV P+ +GG+ Q Y EA A++I+ +NNY + P + K E+A E + +AF++ERS+EDE+ + T D+ AVSYII+F+YI+ +LG + R VESK TLGLGGVI+VL +V A++G + ++ VP++L+I +++PFLVLAVG DNIFI V QR PR E H+GR +G VAPSMLL S++E+ CFFLGA++ MPAVR FAL +G+A+++DFL+Q+T F++L+SLD RQ + D++CC ++K EG++ + F+ YAPF++ ++R V+++F F +L + I VGLDQ+L++P DS+++ YF F+ +YL VGPPVYFV +S + S N C AGC SL I S+ P+++Y+A A SW+DD++ W T SCC+
Sbjct: 530 LTFKDGTSLALSCMADYGAPVFPFLAVGGY--------QGTDYSEAEALIITFSLNNYPADDPRMAQAKLWEEAFLKEMESFQRNTSDKFQVAFSAERSLEDEINRTTIQDLPVFAVSYIIVFLYISLALGSYSRCSRVAVESKATLGLGGVIVVLGAVLAAMGFYSYLGVPSSLVIIQVVPFLVLAVGADNIFIFVLEYQRLPRMPGEQREAHIGRTLGSVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAIILDFLLQMTAFVALLSLDSKRQEASRPDVLCCF-STRKLPPPKEKEGLLLRFFRKIYAPFLLHRFIRPVVMLLFLTLFGANLYLMCNINVGLDQELALPKDSYLIDYFLFLNRYLEVGPPVYFVT-TSGFNFSSEAGMNATCSSAGCKSFSLTQKIQYASEFPDQSYVAIAASSWVDDFIDWLTPSSSCCR 969 HSP 2 Score: 213.772 bits (543), Expect = 7.845e-55 Identity = 152/500 (30.40%), Postives = 234/500 (46.80%), Query Frame = 0
Query: 18 GRXIWFENCSQSPYLENNADKWLN--CAYDGEAKEAP---LLKLERICPHL--DPSEG-VCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGV-NGSEPCSCADCESACE--PPHFEETQVGFYI--VPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKT----KENGITLKDICHAPLEP 500
G ++E C ++P L N C + A+ L L+RICP L P+ CCS KQL +E + +I+ ++L RCP C NF C TC P QS F+ V E +V++ +Y F ++ Y+SC V P+ + A+ MCG +G LC+ RW + G NG P +D F +P+GIQ N + C+ + S CSC DC ++C PP E + FY+ +PG I I +FV+ + + + + S K ++ G +E+ + S H + L FF WGT A +P+ V+ +S + I L G+ ++ +TTDP+ELW++P S++R E+ F D+ F PF+R Q+ V A+N SS+KYD L +K+F I + L LLELQ+ + +++ E I+L+DIC+APL P
Sbjct: 30 GVCTFYEECGKNPELSGGLTSLSNVSCLSNTPARHVTGEHLALLQRICPRLYNGPNTTFACCSTKQLLSLESSMSITKALLTRCPACSDNFVSLHCHNTCSPDQSLFIN--VTRVVERGAGEPPAVVAYEAFY-QRSFAEKAYESCSQVRIPAAASLAVGSMCGVYGSALCNAQRWLNFQGDTGNGLAP--LDITFHLLEPGQALPDGIQPLNGKIAPCNESQGDDSAVCSCQDCAASCPVIPPP-EALRPSFYMGRMPGWLALIIIFTAVFVLLSAVLVRLRVVSNRNKNKA--------------------EGPQEAPKLPHKHKLSPHTI-------------------------LGRFFQNWGTRVASWPLTVLALSFIVVIALAAGLTFIELTTDPVELWSAPKSQARKEKSFHDEHFGPFFRTNQIFVTARNRSSYKYDSLLLGSKNFSGILSLDFLLE-LLELQERLRHLQVWSPEAERNISLQDICYAPLNP 477 HSP 3 Score: 172.17 bits (435), Expect = 5.120e-42 Identity = 95/234 (40.60%), Postives = 138/234 (58.97%), Query Frame = 0
Query: 1035 CPNSDDAID-LK----------RPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAK 1257
CP++D + + LK RP + F +Y+ WFL D P RCPK G AAY SV L + Q VIAS FM +H L+ +D+ EALR +R L++ I + + +VFPY+I VFY+QYLT+ + I +L + F+ +V ++L G D + I+ ++ I MIL++ +G+M W IS NAVSL+NLV AVG+SVEF SHI ++F S + T++ RAK
Sbjct: 981 CPSTDTSFNCLKNCMNRTLGPVRPTAEQFHKYLPWFLNDPPNIRCPKGGLAAYRTSVNLSSDGQ----------VIASQFMAYHKPLRNSQDFTEALRASRLLAANITADLR-KVPGTDPNFEVFPYTISNVFYQQYLTVLPEGIFTLALCFVPTFVVCYLLLGLDMCSGILNLLSIIMILVDTIGLMAVWGISYNAVSLINLVTAVGMSVEFVSHITRSFAVSTKPTRLERAK 1203
BLAST of EMLSAG00000001950 vs. SwissProt
Match: gi|425906049|sp|Q9UHC9.2|NPCL1_HUMAN (RecName: Full=Niemann-Pick C1-like protein 1; Flags: Precursor) HSP 1 Score: 355.525 bits (911), Expect = 3.684e-101 Identity = 185/449 (41.20%), Postives = 280/449 (62.36%), Query Frame = 0
Query: 488 ITLKDICHAPLEPISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKA-LEWEKAYYMDIA------FTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTIDDSCCK 929
+T KD L ++D G PV P+ +GG+ + Y EA A++++ +NNY P + K E+A LE +A+ +A F +ERS+EDE+ + T D+ A SYI++F+YI+ +LG ++W R MV+SK TLGLGGV +VL +V A++G F ++ + ++L+I +++PFLVL+VG DNIFI V QR PR E H+GR +G VAPSMLL S++E+ CFFLGA++ MPAVR FAL +G+A+++DFL+Q++ F++L+SLD RQ + D+ CCV+ ++ GEG++ F+ YAPF++ R V+++F F SL I VGLDQ+L++P DS++L YF F+ +Y VG PVYFV + + S N C AGC++ S I ++ PE++Y+A PA SW+DD++ W SCC+
Sbjct: 530 LTFKDGTALALSCMADYGAPVFPFLAIGGY--------KGKDYSEAEALIMTFSLNNYPAGDPRLAQAKLWEEAFLEEMRAFQRRMAGMFQVTFMAERSLEDEINRTTAEDLPIFATSYIVIFLYISLALGSYSSWSRVMVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLVILQVVPFLVLSVGADNIFIFVLEYQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAVILDFLLQMSAFVALLSLDSKRQEASRLDVCCCVK-PQELPPPGQGEGLLLGFFQKAYAPFLLHWITRGVVLLLFLALFGVSLYSMCHISVGLDQELALPKDSYLLDYFLFLNRYFEVGAPVYFVT-TLGYNFSSEAGMNAICSSAGCNNFSFTQKIQYATEFPEQSYLAIPASSWVDDFIDWLTPSSCCR 968 HSP 2 Score: 210.305 bits (534), Expect = 9.218e-54 Identity = 148/501 (29.54%), Postives = 232/501 (46.31%), Query Frame = 0
Query: 18 GRXIWFENCSQSPYLENNADKWLN--CAYDGEAKEAP---LLKLERICPHL--DPSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGV-NGSEPCSCADCESAC----EPPHFEETQVGFYI--VPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKT----KENGITLKDICHAPLEP 500
G +++ C ++P L + N C + A++ L+ L++ICP L P+ CCS KQL +E + +I+ ++L RCP C NF C TC P QS F+ V + +V++ +Y F ++ YDSC V P+ + A+ MCG +G LC+ RW + G NG P +D F + GIQ N V C+ + CSC DC ++C P + T FY+ +PG I I+ +F V I+ + +A P D S VD K + L+ L FF WGT+ A +P+ ++++S+ + L G+ + +TTDP+ELW++P+S++R E+ F D+ F PF+R QVI+ A N SS++YD L K+F I + L LLELQ+ + +++ + I+L+DIC+APL P
Sbjct: 31 GYCAFYDECGKNPELSGSLMTLSNVSCLSNTPARKITGDHLILLQKICPRLYTGPNTQACCSAKQLVSLEASLSITKALLTRCPACSDNFVNLHCHNTCSPNQSLFI--NVTRVAQLGAGQLPAVVAYEAFY-QHSFAEQSYDSCSRVRVPAAATLAVGTMCGVYGSALCNAQRWLNFQGDTGNGLAP--LDITFHLLEPGQAVGSGIQPLNEGVARCNESQGDDVATCSCQDCAASCPAIARPQALDST---FYLGQMPGSLVLIIILCSVFAVVTILLVGFRVA-------------PARDKS--------------------------KMVDPKKGTSLSDKLSF------STHTLLGQFFQGWGTWVASWPLTILVLSVIPVVALAAGLVFTELTTDPVELWSAPNSQARSEKAFHDQHFGPFFRTNQVILTAPNRSSYRYDSLLLGPKNFSGILDLDLLLE-LLELQERLRHLQVWSPEAQRNISLQDICYAPLNP 477 HSP 3 Score: 137.502 bits (345), Expect = 2.738e-31 Identity = 89/229 (38.86%), Postives = 125/229 (54.59%), Query Frame = 0
Query: 1046 RPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQ-KDNESFFQYNV----------------IASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAK 1257
RP + F +Y+ WFL D P +CPK G AAYS SV L + Q D + + S FM +H LK +DY EALR AR L++ I + + +VFPY+I VFYEQYLT+ + + L + + V+ +L G D + ++ ++ I MIL++ +G M W IS NAVSL+NLV AVG+SVEF SHI ++F S + T + RAK
Sbjct: 1002 RPSVEQFHKYLPWFLNDRPNIKCPKGGLAAYSTSVNLTSDGQVLDTVAILSPRLEYSGTISAHCNLYLLDSTSRFMAYHKPLKNSQDYTEALRAARELAANITADLR-KVPGTDPAFEVFPYTITNVFYEQYLTILPEGLFMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWGISYNAVSLINLVSAVGMSVEFVSHITRSFAISTKPTWLERAK 1229
BLAST of EMLSAG00000001950 vs. SwissProt
Match: gi|73921246|sp|Q6T3U4.1|NPCL1_MOUSE (RecName: Full=Niemann-Pick C1-like protein 1; Flags: Precursor) HSP 1 Score: 335.495 bits (859), Expect = 2.184e-94 Identity = 189/450 (42.00%), Postives = 276/450 (61.33%), Query Frame = 0
Query: 488 ITLKDICHAPLEPISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAYY-------MDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAW-TIDDSCCK 929
+T KD L I+D G PV P+ +GG+ Q Y EA A++I+ INNY + P K E+A E + IAF++ERS+EDE+ + T D+ A+SY+I+F+YI+ +LG + W R V+SK TLGLGGV +VL +V A++G + ++ VP++L+I +++PFLVLAVG DNIFI V QR PR E H+GR +G VAPSMLL S++E+ CFFLGA++ MPAVR FAL +G+A++ DFL+Q+T F++L+SLD RQ + D++CC S+ EG++ F+ Y PF++ ++R V+++F F +L + I VGLDQ L++P DS+++ YF F+ +YL VGPPVYF +S + S N C AGC SL I S+ P ++Y+A A SW+DD++ W T SCC+
Sbjct: 530 LTYKDGTALALSCIADYGAPVFPFLAVGGY--------QGTDYSEAEALIITFSINNYPADDPRMAHAKLWEEAFLKEMQSFQRSTADKFQIAFSAERSLEDEINRTTIQDLPVFAISYLIVFLYISLALGSYSRWSRVAVDSKATLGLGGVAVVLGAVVAAMGFYSYLGVPSSLVIIQVVPFLVLAVGADNIFIFVLEYQRLPRMPGEQREAHIGRTLGSVAPSMLLCSLSEAICFFLGALTSMPAVRTFALTSGLAIIFDFLLQMTAFVALLSLDSKRQEASRPDVVCCF-SSRNLPPPKQKEGLLLCFFRKIYTPFLLHRFIRPVVLLLFLVLFGANLYLMCNISVGLDQDLALPKDSYLIDYFLFLNRYLEVGPPVYFDT-TSGYNFSTEAGMNAICSSAGCESFSLTQKIQYASEFPNQSYVAIAASSWVDDFIDWLTPSSSCCR 969 HSP 2 Score: 192.586 bits (488), Expect = 2.511e-48 Identity = 143/502 (28.49%), Postives = 229/502 (45.62%), Query Frame = 0
Query: 18 GRXIWFENCSQSPYLENNADKWLN--CAYDGEAKEAP---LLKLERICPHL--DPSEG-VCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGVN-GSEPCSCADCESAC----EPPHFEETQVGFYI--VPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPI----FHKEEFLFPLLELQKNIENIKTKENGITLKDICHAPLEP 500
G ++E C ++P L N C + A+ L L+R+CP L P++ CCS KQL ++ + +I+ ++L RCP C NF C TC P QS F+ V + + +V++ +Y F ++ Y+SC V P+ + A+ MCG +G LC+ RW + G NG P +D F + +G++ + + C+ S CSC DC ++C PP + FY+ +PG I I +FV+ ++ + + +AS K ++ GS+E+ + S H V L FF WGT A +P+ V+ +S + I L G+ ++ +TTDP+ELW++P S++R E+ F D+ F PF+R Q+ V AKN SS+KYD L K+F I +E + + + + N I+L+DIC+APL P
Sbjct: 30 GFCTFYEECGKNPELSGGLTSLSNISCLSNTPARHVTGDHLALLQRVCPRLYNGPNDTYACCSTKQLVSLDSSLSITKALLTRCPACSENFVSIHCHNTCSPDQSLFIN--VTRVVQRDPGQLPAVVAYEAFY-QRSFAEKAYESCSRVRIPAAASLAVGSMCGVYGSALCNAQRWLNFQGDTGNGLAP--LDITFHLLEPGQALADGMKPLDGKITPCNESQGEDSAACSCQDCAASCPVIPPPPALRPS---FYMGRMPGWLALIIIFTAVFVLLSVVLVYLRVASNRNKNKT--------------------AGSQEAPNLPRKRRFSPHTV-------------------------LGRFFESWGTRVASWPLTVLALSFIVVIALSVGLTFIELTTDPVELWSAPKSQARKEKAFHDEHFGPFFRTNQIFVTAKNRSSYKYDSLLLGPKNFSGILSLDLLQELLELQERLRHLQVWSHEAQRN-ISLQDICYAPLNP 477 HSP 3 Score: 171.4 bits (433), Expect = 9.578e-42 Identity = 94/234 (40.17%), Postives = 138/234 (58.97%), Query Frame = 0
Query: 1035 CPNSDDAID-LK----------RPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAK 1257
CP++D + + LK RP + F +Y+ WFL D P RCPK G AAY SV L + Q +IAS FM +H L+ +D+ EALR +R L++ I + + +VFPY+I VFY+QYLT+ + I +L + F+ +V ++L G D + I+ ++ I MIL++ +G+M W IS NAVSL+NLV AVG+SVEF SHI ++F S + T++ RAK
Sbjct: 981 CPSTDTSFNCLKNCMNRTLGPVRPTTEQFHKYLPWFLNDTPNIRCPKGGLAAYRTSVNLSSDGQ----------IIASQFMAYHKPLRNSQDFTEALRASRLLAANITAELR-KVPGTDPNFEVFPYTISNVFYQQYLTVLPEGIFTLALCFVPTFVVCYLLLGLDIRSGILNLLSIIMILVDTIGLMAVWGISYNAVSLINLVTAVGMSVEFVSHITRSFAVSTKPTRLERAK 1203
BLAST of EMLSAG00000001950 vs. SwissProt
Match: gi|74676548|sp|Q12200.1|NPC1_YEAST (RecName: Full=Niemann-Pick type C-related protein 1; Flags: Precursor) HSP 1 Score: 305.064 bits (780), Expect = 9.995e-85 Identity = 252/921 (27.36%), Postives = 424/921 (46.04%), Query Frame = 0
Query: 70 CCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSN--GFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGVNGSEPCSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAI-IFVVGXIIFLAIVIASKIL-----KTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDA-KGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIF-WLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTKE----NGITLKDICHAPLEPISDGGIPVQPY--YMLGGF---------IPENEPFPQN--PSYHE---------------ASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAYYMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEH-VGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWT--IDDSCCKYRAVDMSVCQSNGESK 945
CC++ Q+ + N + ++ CP CL NF FC TC Q F V + +++E+ +++ + ++ + YDSCK + + +G A+ L+ G G K S ++ ++LG G +PFQI+Y + E +N V +CD + C+C+DC+ +C PH + P DG + + F + +IF I + K + N M+ D D + P + S N+E + G L N FT G F + P ++I ++ IF + + TDPI LW S +S E+++FD F PFYR Q+ V + ET GP+ E L ++EN T+E I +D+C P E D ++ + Y G + E FP N P++ + A A V+++++ N+ S N E + E L+ + + I+F +E S+E EL DIST+A+SY++MF+Y T++L +R ++++ LG+ G++IVL S+ + G + +TLII E+IPFL+LA+G DNIF++ R+ E ++ + +G ++PS+L++ + ++ CF + A MPAV FA+Y+ ++++ + ++Q+T ++S++SL R NY I G E K FY + + + ++IIF WF TSL P I+ GLDQ L++P DS+++ YF + +L+VGPPVY VV N+DL+ Q K CG + +SL N+ ++ ++ I P +W+DDY + +D CC+ + VC + S+
Sbjct: 75 CCTKDQVVALRDNLQKAQPLISSCPACLKNFNNLFCHFTCAADQGRF----VNITKVEKSKEDKDIVAELDVFMNSSWASEFYDSCKNIKFSATNGYAMDLIGG--GAKNYS--QFLKFLGDAKPMLGGSPFQINYKYDLANEEKEWQE----FNDEVYACD---DAQYKCACSDCQESC--PHLK---------PLKDGVCKVGPLPCFSLSVLIFYTICALFAFMWYYLCKRKKNGAMIVDDD--------IVPESGSLDESETNVFESFNNETNFFNGK--------------------LANLFTKVGQFSVENPYKILITTVFSIFVFSFIIFQYATLETDPINLWVSKNSEKFKEKEYFDDNFGPFYRTEQIFV-------------VNET---GPVLSYET-----LHWWFDVENFITEELQSSENIGYQDLCFRPTE---DSTCVIESFTQYFQGALPNKDSWKRELQECGKFPVNCLPTFQQPLKTNLLFSDDDILNAHAFVVTLLLTNHTQ-SANRWEERLEEYLLDLKVPEGLRISFNTEISLEKELNNN--NDISTVAISYLMMFLYATWAL------RRKDGKTRLLLGISGLLIVLASIVCAAGFLTLFGLKSTLIIAEVIPFLILAIGIDNIFLITHEYDRNCEQKPEYSIDQKIISAIGRMSPSILMSLLCQTGCFLIAAFVTMPAVHNFAIYSTVSVIFNGVLQLTAYVSILSLYEKRS--NYKQI-------------TGNEETKESFLKTFYFKMLTQ---KRLIIIIFSAWFFTSLVFLPEIQFGLDQTLAVPQDSYLVDYFKDVYSFLNVGPPVYMVV--KNLDLTKRQNQQKICGKFTTCER--DSLANVLEQERHRSTITEPLANWLDDYFMFLNPQNDQCCRLKKGTDEVCPPSFPSR 886 HSP 2 Score: 98.2117 bits (243), Expect = 3.027e-19 Identity = 71/208 (34.13%), Postives = 112/208 (53.85%), Query Frame = 0
Query: 1047 PGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGF--DFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETK 1252
P K F Y+ ++ + P + CP G A YS ++ NE+ +V AS F T H L++ KD+ +A R+SS + +F YS FY+F+ QY T+ T+ L+ S +I ++ FI + F + +S ++ +V+ MI++++ +M ISLNAVSLVNL++ VG+ VEFC HI ++FT ETK
Sbjct: 905 PEGKDFMEYLSIWI-NAPSDPCPLGGRAPYSTALVY-------NET----SVSASVFRTAHHPLRSQKDFIQAYSDGVRISSSFPE------------LDMFAYSPFYIFFVQYQTLGPLTLK-LIGS--AIILIFFISSVFLQNIRSSFLLALVVTMIIVDIGALMALLGISLNAVSLVNLIICVGLGVEFCVHIVRSFTVVPSETK 1085
BLAST of EMLSAG00000001950 vs. SwissProt
Match: gi|37999494|sp|Q19127.2|NPC1_CAEEL (RecName: Full=Niemann-Pick C1 protein homolog 1; Flags: Precursor) HSP 1 Score: 275.789 bits (704), Expect = 1.783e-74 Identity = 251/991 (25.33%), Postives = 415/991 (41.88%), Query Frame = 0
Query: 55 KLERICPHLDPSEG-VCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMT----SNHF--ETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGT-ALKLMCGKWGDKLCSPYRWFRYLGSLSNGFT-PFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGVNGSEP-CSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTF-RP-----------------------------FYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEE-------FLFPLLELQKNIENIKTKEN------------------GITLKDICH------APLEPISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAYY------------MDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLG-----ENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRD----PRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDI-----ICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTIDDS-CCKYRAVD-MSVCQSNGESKA 946
K+ CPHL + +CC+ Q + + K + ILGRCP+C NF K +C TC P Q F+ M F E Q + ++ V Y ++ +F + ++ SCK V + G AL++MC C+ W ++G+ + P ++ + P + + N CD P CS ++C E + + G G + I + + LA + + +L +F D D Y T +G E N I+R GA + ++ N G + P + ++ I G+ + +T+ +++W+SP SR+R E F+ F RP F + ++ KN+S+ D G T + + ++ + P Q N E++ K N T + + H P+ + G+ Y GG N F +N + H+A+ SIM+ PE ++KA WEK + + +F +ERSI DE+ + +I T+ ++ + Y+TFSLG EN W +V S+I LG+ VII LLS S GIF + + F+V +G F++V+ + P + + E VG ++ P+M +S+ + FF+G +D+PA+R F LYAG+A+LID ++ T F++L D R+ + + I + G+ RQ + + + F APF+M R IIF F T++ ++ +I VG DQ ++ + S++ +F +++K+ VGPPV+F VD +D P +QNKFC GCSD S +++N E+TY++ +WID+YL W S CCK D + C +N A
Sbjct: 60 KMVEFCPHLLTGDNKLCCTPSQAEGLTKQIAQARHILGRCPSCFDNFAKLWCEFTCSPNQQDFVSISEMKPIEKKEGFTPEYQPAEAYVNTVEYRLSTDFAEGMFSSCKDV---TFGGQPALRVMCTS---TPCTLTNWLEFIGTQNLDLNIPIHTKFLLYDPIKTPP-SDRSTYMNVNFTGCDKSARVGWPACSTSECNKE-EYANLIDLDDG-----KTSGQTCNVHGIACLNIFVMLAFIGSLAVLLCVGFVFTSYDED---YTNLRQTQSGEESPKR------------------------NRIKRTGAWIHNFMENNARDIGMMAGRNPKSHFFIGCAVLIFCLPGMIYHKESTNVVDMWSSPRSRARQEEMVFNANFGRPQRYQQIMLLSHRDFQSSGKLYGPVFHKDIFEELFDILNAIKNISTQDSD---GRTITLDDVCYRPMGPGYDCLIMSPTNYFQGNKEHLDMKSNKEETVSEDDDAFDYFSSEATTDEWMNHMAACIDQPMSQKTKSGLSCMGTY--GGPSAPNMVFGKNSTNHQAAN---SIMMTILVTQRTEPE----IQKAELWEKEFLKFCKEYREKSPKVIFSFMAERSITDEIENDAKDEIVTVVIALAFLIGYVTFSLGRYFVCENQLWS-ILVHSRICLGMLSVIINLLSSFCSWGIFSMFGIHPVKNALVVQFFVVTLLGVCRTFMVVKYYAQQRVSMPYMSPDQCPEIVGMVMAGTMPAMFSSSLGCAFSFFIGGFTDLPAIRTFCLYAGLAVLIDVVLHCTIFLALFVWDTQRELNGKPEFFFPYQIKDLLGAYLIGRQRATDTFMTQFFHFQVAPFLMHRMTRIITGIIFIASFITTVILSSKISVGFDQSMAFTEKSYISTHFRYLDKFFDVGPPVFFTVD-GELDWHRPDVQNKFCTFPGCSDTSFGNIMNYAVGHTEQTYLSGEMYNWIDNYLEWISRKSPCCKVYVHDPNTFCSTNRNKSA 996 HSP 2 Score: 103.219 bits (256), Expect = 9.060e-21 Identity = 71/261 (27.20%), Postives = 117/261 (44.83%), Query Frame = 0
Query: 1013 DNQNSVQTKKGRSKRATDSCIKCPNSD--------DAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILK--TPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTSHQST 1263
D T + +S +C C + D +I RP + F R+++ FLED P C G A++ ++ + + + AS FMTFH L D+ +A+ AR +S +E SI+ VF YS + FYEQY T+ L ++ + + + + G D + V+ +++ MY +NI +NA+S NLVM+ GI +EF ++ K + S+ + RAK +ST
Sbjct: 983 DPNTFCSTNRNKSALDDKACRTCMDFDYVANSYPKSSIMYHRPSIEVFYRHLRHFLEDTPNSECVFGGRASFKDAISFTSRGR----------IQASQFMTFHKKLSISNSSDFIKAMDTARMVSRRLERSIDDT-------AHVFAYSKIFPFYEQYSTIMPILTTQLFITVVGVFGIICVTLGIDVKGAACAVICQVSNYFHIVAFMYIFNIPVNALSATNLVMSSGILIEFSVNVLKGYACSLRQ----RAKDRAEST 1222
BLAST of EMLSAG00000001950 vs. SwissProt
Match: gi|37999933|sp|P34389.2|NPC2_CAEEL (RecName: Full=Niemann-Pick C1 protein homolog 2; Flags: Precursor) HSP 1 Score: 198.364 bits (503), Expect = 4.239e-50 Identity = 237/1010 (23.47%), Postives = 401/1010 (39.70%), Query Frame = 0
Query: 24 ENCSQSPYLENNADKWLNCAYDGEAKEAPLLKLERICPHLDPSEG---VCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFT-PFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGVNGSEP-CSCADCESACEP-------PHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRIT-----------------------QVIVKAKNL------SSFKYDDFLGETKSFGPIF--HKEEFLFPLLELQK---NIEN---------IKTKENGITLKDICHAPL--------EPISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAY----------YMDIAFTSERSIEDEL--AKETYGDISTIAVSYIIMFIYITFSLGE--NTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRD------PRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFL-GAI-----SDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQND------------NYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLIN--LWSKQPEKTYIAAPAQSWIDDYLAWTI-DDSCCK 929
E S P + N +L + + E+ C +L E VCC+E QL M + +A+ILG CP+C NF K +C TC P QS F++ VM ET +V+ + + V +FV+ +Y+SC+ T +G AL+LM G K+ S ++ ++G+ + + P ++ FS IP C P C DC + H T+V P + + I + + ++F ILK + P+G+D Y G N EV +G L R + K+P+ + + L +A C+G F + T ++ ++ +R F +F P +RI Q++ +NL SS K DD + PI H + P Q N EN I ++ LK PL + P+ P + GG NE Y+ A ++I+++I PE+ +A+ WE A+ + + F +E S+ +E+ A ET +S IA + +++++ + ++ +V K+ + + V+I ++SV SIG+F V AT ++ F++ +G + IF++++T Q + P + + ++ P +L S+ STC FL G + MPAV FA +AG+A+L+D + + L D R+ N I C+ N+R FK AP ++K+ R + FF + T +E G +Q ++ + S++ K+F + + L++GPP++FVV+ +V P +QNKFC AGC D S+ + I +++ + Y+ W+D YL + SCCK
Sbjct: 37 EEDSNHPPCKTNKSTYLPITVTRSLNPTYMARFEKYCSYLVQEEDKAQVCCTELQLKGMTDRISNAATILGSCPSCFDNFAKLWCQFTCSPDQSKFMK--VM-----ETTGPKNVVVKMEFKVNRDFVEGLYESCRH--TWFANGLALRLM--SLGGKV-SFENFYGFMGTKNLAQSIPINTEFQFSRMKNAMNIP---------TTPCHKSAGPKVPACGAIDCPTNAHQLVDISKVEHLG-TKVFHPHFPDFEWLLKICGCLALTVLLVF--------ILKYSCHRRSAPNGEDGCYVDL-----------------GKGNLEVQFEG---------LCAR---------------YANAVIKHPLIFVSLGLIVAAACCSGNFKFHSLTHSVDQVSAADGETRRNEKKFIHSFGPNHRIEQIFINLPPTTKSMFNMPLFEEMFQLVGNIQNLTACYGNSSVKLDDI-----CYKPIGKNHGCAIMSPTNYFQNKWTNFENAGPPTIDDEIFDDQHWEHLKYCIRNPLTVSTYSEMSCFGEFSGPIDPILVFGG---SNESIKGAEMYYTARTIMITVLIRG-------PED-----QAIAWETAFLNMMSRYEMKHANFTFMTETSVAEEIHTAVETDKIVSVIACAAVLIWVITMLGINHWPESSILSALVHHKLLISISAVMISVISVWCSIGMFSLFGVHATDNAIVVLFFVITCLGINRIFVIIRTFQANGHCYGLPNISYREMNHRISNVMRRSIPIVLTNSLICSTCLFLAGGVLPYVSVSMPAVEVFARHAGLAILMDTAFYLLVMLPLFQYDARREMSGKCEIWPWYELSNESKINLCMEAVDGNLRSP------VDWFKLAIAPLLLKKICRIWIATFFFVSLIIACYCTLCLEFGFNQVMAFSETSYLTKHFQNMNENLNIGPPLWFVVE-GDVKWHDPKMQNKFCTLAGCDDNSMGNKIRSLAYAENYKGNYLHGDVNIWLDSYLQFMHPRGSCCK 948 HSP 2 Score: 78.5666 bits (192), Expect = 2.485e-13 Identity = 56/207 (27.05%), Postives = 100/207 (48.31%), Query Frame = 0
Query: 1052 FRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPK--DYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRA 1256
F R + FLE P +C G A ++ L + + + ++ F TF L Y+A R+A+ L+ +IE + + GVKV+ YS F+ +YEQYLT+ + +++ + + + S++ V V+ ++LM MY I++N VS++N+ M++GI+VEF + F +S + + RA
Sbjct: 981 FYRNLHHFLETPPSIQCAHGGMALAKPAINLTRNGK----------IQSAYFSTFFKKLNLSDSIQLYDAWRFAKYLADDIEREL------EIPGVKVYVYSTFFPYYEQYLTLSTTVYTLVVLVLFVAFVTISLFLRVNLAGSLVTVFVLLSSYLHLMEWMYLLGITVNVVSVINMAMSLGIAVEFFGQMLHGFYNSKKPKREERA 1171
BLAST of EMLSAG00000001950 vs. Select Arthropod Genomes
Match: AHN54311.1 (Niemann-Pick type C-1a, isoform G [Drosophila melanogaster]) HSP 1 Score: 834.713 bits (2155), Expect = 0.000e+0 Identity = 502/1323 (37.94%), Postives = 711/1323 (53.74%), Query Frame = 0
Query: 21 IWFENCSQSPYLENNADKWLNCAYDGEAKEAP---LLKLERICPHL--DPSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQF--YNTVVESCDVGVNGSEP-CSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENGITLKDICHA-----------------------------------------------------PLEPISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAY--------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAW-TIDDSCCKYRAVDMSVCQSNGESKAKAQSALSFIDKFFENDDFFGGNSVNDFDDYDHEEEEKEESNSSKNGVL--PESMFSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNES--FFQYNVI----ASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
+W+ C+ + + + NC Y+G AKE L L++ C L + CC + Q++++ KN ++ +IL RCP+C+ N ++ C TC P+Q+ F+ V+ + + +E IS+V +++ E++ + Y SC V P A LMCG + C+P +WF ++G +N + PFQI Y+ +H P F N C+ V+ P CSC+DC+ +C E + + + G+D IMA +F+VG ++FL L TQ + F + DG+D + D P + N S ++ GA E +L FFT WGT+ A P +I S+ + L GI ++ +TTDP++LWASP+S+SR+ER+FFD F PFYR+ Q+I+KA NL ++ G +FGP+F +E FL +L+LQ+ I+ I NG LKDIC+A P ++ G PV P LGGF+P + + + A+A++++ ++ N+ HN + LE AL WEK + YMDIAFTSERSIEDEL +E+ D+ TI VSY+IMF+YI SLG +KR ++SKITLG+GGVIIVL SV +S+G+FG+I +PATLII E+IPFLVLAVG DNIFI+VQT QRD R ET + VGRI+G+V PSMLLTS++ES CFFLG +SDMPAVRAFALYAG+AL+IDFL+Q+TCF+SL +LD R+ +N DI C ++G K + EG++YK F Y PF+MK+ VRA+V++IFF W C S+A+ PRI++GLDQ+L+MP DSFVL YF + + L++GPPVYFV+ ++ + QN C G C+D+S+ + I L S+ +TYIA PA SWIDDY W SCCKYR C H++ N +KN +L E F KY F+ ++ D D+C K G A+ G YS S H + + E+ F Y+ I A F+ + K + + L+ R +S NG + V+VFPYS+FYVFYEQYLTMWSDT+ S+ +S LSI +VTF+L GFD +++++V+ I MI++NL G+MY+WNISLNAVSLVNLVMAVGISVEFCSH+ +F S ++I RA S
Sbjct: 34 VWYGVCNTNDFSHSQ-----NCPYNGTAKEMATDGLELLKKRCGFLLENSENKFCCDKNQVELLNKNVELAGNILDRCPSCMENLVRHICQFTCSPKQAEFMH--VVATQKNKKGDEY--ISSVDLHISTEYINKTYKSCSQVSVPQTGQLAFDLMCGAYSASRCNPTKWFNFMGDATNPYVPFQITYI-----QHEPKSNSNNFTPLNVTTVPCNQAVSSKLPACSCSDCDLSCPQGPPEPPRPEPFKIVGLDAYFVIMAAVFLVGVLVFLM----GSFLFTQDDNFQV-DGND-VSDEMPYSENDS------------------------------YFEKLGAHTETFLETFFTKWGTYFASNPGLTLIAGASLVVILGYGINFIEITTDPVKLWASPNSKSRLEREFFDTKFSPFYRLEQIIIKAVNLPQIVHNTSNGP-YTFGPVFDRE-FLTKVLDLQEGIKEINA--NGTQLKDICYAPLSDDGSEIDVSQCVVQSIWGYFGDDRERLDDHDEDNGFNVTYLDALYDCISNPYLCLAPYGGPVDPAIALGGFLPPGDQLTGSTKFELANAIILTFLVKNH-HNKTD------LENALTWEKKFVEFMTNYTKNNMSQYMDIAFTSERSIEDELNRESQSDVLTILVSYLIMFMYIAISLGHVKEFKRVFIDSKITLGIGGVIIVLASVVSSVGVFGYIGLPATLIIVEVIPFLVLAVGVDNIFILVQTHQRDQRKPNETLEQQVGRILGKVGPSMLLTSLSESFCFFLGGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRREENRMDICCFIKGKKPD-SITSNEGLLYKFFSSVYVPFLMKKIVRASVMVIFFAWLCFSIAIAPRIDIGLDQELAMPQDSFVLHYFQSLNENLNIGPPVYFVL-KGDLAYTNSSDQNLVCAGQYCNDDSVLTQIYLASRHSNQTYIARPASSWIDDYFDWAAAASSCCKYRKDSGDFCP--------------------------------------HQDTSCLRCNITKNSLLRPEEKEFVKYLPFFLKDNPD-----------------DTCAKA------------GHAAY------------------GGAVRYSNS-----HERLNIEASYFMAYHTILKSSADYFLALESARKISANITQMLQ-GRLMS-------NGVPMASALTVEVFPYSVFYVFYEQYLTMWSDTLQSMGISVLSIFVVTFVLMGFDVHSALVVVITITMIVVNLGGLMYYWNISLNAVSLVNLVMAVGISVEFCSHLVHSFATSKSVSQIDRAADS 1195
BLAST of EMLSAG00000001950 vs. Select Arthropod Genomes
Match: AHN54310.1 (Niemann-Pick type C-1a, isoform F [Drosophila melanogaster]) HSP 1 Score: 834.713 bits (2155), Expect = 0.000e+0 Identity = 502/1323 (37.94%), Postives = 711/1323 (53.74%), Query Frame = 0
Query: 21 IWFENCSQSPYLENNADKWLNCAYDGEAKEAP---LLKLERICPHL--DPSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQF--YNTVVESCDVGVNGSEP-CSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENGITLKDICHA-----------------------------------------------------PLEPISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAY--------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAW-TIDDSCCKYRAVDMSVCQSNGESKAKAQSALSFIDKFFENDDFFGGNSVNDFDDYDHEEEEKEESNSSKNGVL--PESMFSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNES--FFQYNVI----ASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
+W+ C+ + + + NC Y+G AKE L L++ C L + CC + Q++++ KN ++ +IL RCP+C+ N ++ C TC P+Q+ F+ V+ + + +E IS+V +++ E++ + Y SC V P A LMCG + C+P +WF ++G +N + PFQI Y+ +H P F N C+ V+ P CSC+DC+ +C E + + + G+D IMA +F+VG ++FL L TQ + F + DG+D + D P + N S ++ GA E +L FFT WGT+ A P +I S+ + L GI ++ +TTDP++LWASP+S+SR+ER+FFD F PFYR+ Q+I+KA NL ++ G +FGP+F +E FL +L+LQ+ I+ I NG LKDIC+A P ++ G PV P LGGF+P + + + A+A++++ ++ N+ HN + LE AL WEK + YMDIAFTSERSIEDEL +E+ D+ TI VSY+IMF+YI SLG +KR ++SKITLG+GGVIIVL SV +S+G+FG+I +PATLII E+IPFLVLAVG DNIFI+VQT QRD R ET + VGRI+G+V PSMLLTS++ES CFFLG +SDMPAVRAFALYAG+AL+IDFL+Q+TCF+SL +LD R+ +N DI C ++G K + EG++YK F Y PF+MK+ VRA+V++IFF W C S+A+ PRI++GLDQ+L+MP DSFVL YF + + L++GPPVYFV+ ++ + QN C G C+D+S+ + I L S+ +TYIA PA SWIDDY W SCCKYR C H++ N +KN +L E F KY F+ ++ D D+C K G A+ G YS S H + + E+ F Y+ I A F+ + K + + L+ R +S NG + V+VFPYS+FYVFYEQYLTMWSDT+ S+ +S LSI +VTF+L GFD +++++V+ I MI++NL G+MY+WNISLNAVSLVNLVMAVGISVEFCSH+ +F S ++I RA S
Sbjct: 34 VWYGVCNTNDFSHSQ-----NCPYNGTAKEMATDGLELLKKRCGFLLENSENKFCCDKNQVELLNKNVELAGNILDRCPSCMENLVRHICQFTCSPKQAEFMH--VVATQKNKKGDEY--ISSVDLHISTEYINKTYKSCSQVSVPQTGQLAFDLMCGAYSASRCNPTKWFNFMGDATNPYVPFQITYI-----QHEPKSNSNNFTPLNVTTVPCNQAVSSKLPACSCSDCDLSCPQGPPEPPRPEPFKIVGLDAYFVIMAAVFLVGVLVFLM----GSFLFTQDDNFQV-DGND-VSDEMPYSENDS------------------------------YFEKLGAHTETFLETFFTKWGTYFASNPGLTLIAGASLVVILGYGINFIEITTDPVKLWASPNSKSRLEREFFDTKFSPFYRLEQIIIKAVNLPQIVHNTSNGP-YTFGPVFDRE-FLTKVLDLQEGIKEINA--NGTQLKDICYAPLSDDGSEIDVSQCVVQSIWGYFGDDRERLDDHDEDNGFNVTYLDALYDCISNPYLCLAPYGGPVDPAIALGGFLPPGDQLTGSTKFELANAIILTFLVKNH-HNKTD------LENALTWEKKFVEFMTNYTKNNMSQYMDIAFTSERSIEDELNRESQSDVLTILVSYLIMFMYIAISLGHVKEFKRVFIDSKITLGIGGVIIVLASVVSSVGVFGYIGLPATLIIVEVIPFLVLAVGVDNIFILVQTHQRDQRKPNETLEQQVGRILGKVGPSMLLTSLSESFCFFLGGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRREENRMDICCFIKGKKPD-SITSNEGLLYKFFSSVYVPFLMKKIVRASVMVIFFAWLCFSIAIAPRIDIGLDQELAMPQDSFVLHYFQSLNENLNIGPPVYFVL-KGDLAYTNSSDQNLVCAGQYCNDDSVLTQIYLASRHSNQTYIARPASSWIDDYFDWAAAASSCCKYRKDSGDFCP--------------------------------------HQDTSCLRCNITKNSLLRPEEKEFVKYLPFFLKDNPD-----------------DTCAKA------------GHAAY------------------GGAVRYSNS-----HERLNIEASYFMAYHTILKSSADYFLALESARKISANITQMLQ-GRLMS-------NGVPMASALTVEVFPYSVFYVFYEQYLTMWSDTLQSMGISVLSIFVVTFVLMGFDVHSALVVVITITMIVVNLGGLMYYWNISLNAVSLVNLVMAVGISVEFCSHLVHSFATSKSVSQIDRAADS 1195
BLAST of EMLSAG00000001950 vs. Select Arthropod Genomes
Match: AHN54309.1 (Niemann-Pick type C-1a, isoform E [Drosophila melanogaster]) HSP 1 Score: 834.713 bits (2155), Expect = 0.000e+0 Identity = 502/1323 (37.94%), Postives = 711/1323 (53.74%), Query Frame = 0
Query: 21 IWFENCSQSPYLENNADKWLNCAYDGEAKEAP---LLKLERICPHL--DPSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQF--YNTVVESCDVGVNGSEP-CSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENGITLKDICHA-----------------------------------------------------PLEPISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAY--------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAW-TIDDSCCKYRAVDMSVCQSNGESKAKAQSALSFIDKFFENDDFFGGNSVNDFDDYDHEEEEKEESNSSKNGVL--PESMFSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNES--FFQYNVI----ASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
+W+ C+ + + + NC Y+G AKE L L++ C L + CC + Q++++ KN ++ +IL RCP+C+ N ++ C TC P+Q+ F+ V+ + + +E IS+V +++ E++ + Y SC V P A LMCG + C+P +WF ++G +N + PFQI Y+ +H P F N C+ V+ P CSC+DC+ +C E + + + G+D IMA +F+VG ++FL L TQ + F + DG+D + D P + N S ++ GA E +L FFT WGT+ A P +I S+ + L GI ++ +TTDP++LWASP+S+SR+ER+FFD F PFYR+ Q+I+KA NL ++ G +FGP+F +E FL +L+LQ+ I+ I NG LKDIC+A P ++ G PV P LGGF+P + + + A+A++++ ++ N+ HN + LE AL WEK + YMDIAFTSERSIEDEL +E+ D+ TI VSY+IMF+YI SLG +KR ++SKITLG+GGVIIVL SV +S+G+FG+I +PATLII E+IPFLVLAVG DNIFI+VQT QRD R ET + VGRI+G+V PSMLLTS++ES CFFLG +SDMPAVRAFALYAG+AL+IDFL+Q+TCF+SL +LD R+ +N DI C ++G K + EG++YK F Y PF+MK+ VRA+V++IFF W C S+A+ PRI++GLDQ+L+MP DSFVL YF + + L++GPPVYFV+ ++ + QN C G C+D+S+ + I L S+ +TYIA PA SWIDDY W SCCKYR C H++ N +KN +L E F KY F+ ++ D D+C K G A+ G YS S H + + E+ F Y+ I A F+ + K + + L+ R +S NG + V+VFPYS+FYVFYEQYLTMWSDT+ S+ +S LSI +VTF+L GFD +++++V+ I MI++NL G+MY+WNISLNAVSLVNLVMAVGISVEFCSH+ +F S ++I RA S
Sbjct: 34 VWYGVCNTNDFSHSQ-----NCPYNGTAKEMATDGLELLKKRCGFLLENSENKFCCDKNQVELLNKNVELAGNILDRCPSCMENLVRHICQFTCSPKQAEFMH--VVATQKNKKGDEY--ISSVDLHISTEYINKTYKSCSQVSVPQTGQLAFDLMCGAYSASRCNPTKWFNFMGDATNPYVPFQITYI-----QHEPKSNSNNFTPLNVTTVPCNQAVSSKLPACSCSDCDLSCPQGPPEPPRPEPFKIVGLDAYFVIMAAVFLVGVLVFLM----GSFLFTQDDNFQV-DGND-VSDEMPYSENDS------------------------------YFEKLGAHTETFLETFFTKWGTYFASNPGLTLIAGASLVVILGYGINFIEITTDPVKLWASPNSKSRLEREFFDTKFSPFYRLEQIIIKAVNLPQIVHNTSNGP-YTFGPVFDRE-FLTKVLDLQEGIKEINA--NGTQLKDICYAPLSDDGSEIDVSQCVVQSIWGYFGDDRERLDDHDEDNGFNVTYLDALYDCISNPYLCLAPYGGPVDPAIALGGFLPPGDQLTGSTKFELANAIILTFLVKNH-HNKTD------LENALTWEKKFVEFMTNYTKNNMSQYMDIAFTSERSIEDELNRESQSDVLTILVSYLIMFMYIAISLGHVKEFKRVFIDSKITLGIGGVIIVLASVVSSVGVFGYIGLPATLIIVEVIPFLVLAVGVDNIFILVQTHQRDQRKPNETLEQQVGRILGKVGPSMLLTSLSESFCFFLGGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRREENRMDICCFIKGKKPD-SITSNEGLLYKFFSSVYVPFLMKKIVRASVMVIFFAWLCFSIAIAPRIDIGLDQELAMPQDSFVLHYFQSLNENLNIGPPVYFVL-KGDLAYTNSSDQNLVCAGQYCNDDSVLTQIYLASRHSNQTYIARPASSWIDDYFDWAAAASSCCKYRKDSGDFCP--------------------------------------HQDTSCLRCNITKNSLLRPEEKEFVKYLPFFLKDNPD-----------------DTCAKA------------GHAAY------------------GGAVRYSNS-----HERLNIEASYFMAYHTILKSSADYFLALESARKISANITQMLQ-GRLMS-------NGVPMASALTVEVFPYSVFYVFYEQYLTMWSDTLQSMGISVLSIFVVTFVLMGFDVHSALVVVITITMIVVNLGGLMYYWNISLNAVSLVNLVMAVGISVEFCSHLVHSFATSKSVSQIDRAADS 1195
BLAST of EMLSAG00000001950 vs. Select Arthropod Genomes
Match: ADV37021.1 (Niemann-Pick type C-1a, isoform D [Drosophila melanogaster]) HSP 1 Score: 829.706 bits (2142), Expect = 0.000e+0 Identity = 501/1326 (37.78%), Postives = 713/1326 (53.77%), Query Frame = 0
Query: 21 IWFENCSQSPYLENNADKWLNCAYDGEAKEAP---LLKLERICPHL--DPSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQF--YNTVVESCDVGVNGSEP-CSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNL---FMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENGITLKDICHA-----------------------------------------------------PLEPISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAY--------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAW-TIDDSCCKYRAVDMSVCQSNGESKAKAQSALSFIDKFFENDDFFGGNSVNDFDDYDHEEEEKEESNSSKNGVL--PESMFSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNES--FFQYNVI----ASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
+W+ C+ + + + NC Y+G AKE L L++ C L + CC + Q++++ KN ++ +IL RCP+C+ N ++ C TC P+Q+ F+ V+ + + +E IS+V +++ E++ + Y SC V P A LMCG + C+P +WF ++G +N + PFQI Y+ +H P F N C+ V+ P CSC+DC+ +C E + + + G+D IMA +F+VG ++FL + S + S++ F + DG+D + D P + N S ++ GA E +L FFT WGT+ A P +I S+ + L GI ++ +TTDP++LWASP+S+SR+ER+FFD F PFYR+ Q+I+KA NL ++ G +FGP+F +E FL +L+LQ+ I+ I NG LKDIC+A P ++ G PV P LGGF+P + + + A+A++++ ++ N+ HN + LE AL WEK + YMDIAFTSERSIEDEL +E+ D+ TI VSY+IMF+YI SLG +KR ++SKITLG+GGVIIVL SV +S+G+FG+I +PATLII E+IPFLVLAVG DNIFI+VQT QRD R ET + VGRI+G+V PSMLLTS++ES CFFLG +SDMPAVRAFALYAG+AL+IDFL+Q+TCF+SL +LD R+ +N DI C ++G K + EG++YK F Y PF+MK+ VRA+V++IFF W C S+A+ PRI++GLDQ+L+MP DSFVL YF + + L++GPPVYFV+ ++ + QN C G C+D+S+ + I L S+ +TYIA PA SWIDDY W SCCKYR C H++ N +KN +L E F KY F+ ++ D D+C K G A+ G YS S H + + E+ F Y+ I A F+ + K + + L+ R +S NG + V+VFPYS+FYVFYEQYLTMWSDT+ S+ +S LSI +VTF+L GFD +++++V+ I MI++NL G+MY+WNISLNAVSLVNLVMAVGISVEFCSH+ +F S ++I RA S
Sbjct: 34 VWYGVCNTNDFSHSQ-----NCPYNGTAKEMATDGLELLKKRCGFLLENSENKFCCDKNQVELLNKNVELAGNILDRCPSCMENLVRHICQFTCSPKQAEFMH--VVATQKNKKGDEY--ISSVDLHISTEYINKTYKSCSQVSVPQTGQLAFDLMCGAYSASRCNPTKWFNFMGDATNPYVPFQITYI-----QHEPKSNSNNFTPLNVTTVPCNQAVSSKLPACSCSDCDLSCPQGPPEPPRPEPFKIVGLDAYFVIMAAVFLVGVLVFL---MGSFLFTQGSSMDDNFQV-DGND-VSDEMPYSENDS------------------------------YFEKLGAHTETFLETFFTKWGTYFASNPGLTLIAGASLVVILGYGINFIEITTDPVKLWASPNSKSRLEREFFDTKFSPFYRLEQIIIKAVNLPQIVHNTSNGP-YTFGPVFDRE-FLTKVLDLQEGIKEINA--NGTQLKDICYAPLSDDGSEIDVSQCVVQSIWGYFGDDRERLDDHDEDNGFNVTYLDALYDCISNPYLCLAPYGGPVDPAIALGGFLPPGDQLTGSTKFELANAIILTFLVKNH-HNKTD------LENALTWEKKFVEFMTNYTKNNMSQYMDIAFTSERSIEDELNRESQSDVLTILVSYLIMFMYIAISLGHVKEFKRVFIDSKITLGIGGVIIVLASVVSSVGVFGYIGLPATLIIVEVIPFLVLAVGVDNIFILVQTHQRDQRKPNETLEQQVGRILGKVGPSMLLTSLSESFCFFLGGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRREENRMDICCFIKGKKPD-SITSNEGLLYKFFSSVYVPFLMKKIVRASVMVIFFAWLCFSIAIAPRIDIGLDQELAMPQDSFVLHYFQSLNENLNIGPPVYFVL-KGDLAYTNSSDQNLVCAGQYCNDDSVLTQIYLASRHSNQTYIARPASSWIDDYFDWAAAASSCCKYRKDSGDFCP--------------------------------------HQDTSCLRCNITKNSLLRPEEKEFVKYLPFFLKDNPD-----------------DTCAKA------------GHAAY------------------GGAVRYSNS-----HERLNIEASYFMAYHTILKSSADYFLALESARKISANITQMLQ-GRLMS-------NGVPMASALTVEVFPYSVFYVFYEQYLTMWSDTLQSMGISVLSIFVVTFVLMGFDVHSALVVVITITMIVVNLGGLMYYWNISLNAVSLVNLVMAVGISVEFCSHLVHSFATSKSVSQIDRAADS 1199
BLAST of EMLSAG00000001950 vs. Select Arthropod Genomes
Match: ADV37020.1 (Niemann-Pick type C-1a, isoform C [Drosophila melanogaster]) HSP 1 Score: 829.706 bits (2142), Expect = 0.000e+0 Identity = 501/1326 (37.78%), Postives = 713/1326 (53.77%), Query Frame = 0
Query: 21 IWFENCSQSPYLENNADKWLNCAYDGEAKEAP---LLKLERICPHL--DPSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQF--YNTVVESCDVGVNGSEP-CSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNL---FMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENGITLKDICHA-----------------------------------------------------PLEPISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAY--------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAW-TIDDSCCKYRAVDMSVCQSNGESKAKAQSALSFIDKFFENDDFFGGNSVNDFDDYDHEEEEKEESNSSKNGVL--PESMFSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNES--FFQYNVI----ASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
+W+ C+ + + + NC Y+G AKE L L++ C L + CC + Q++++ KN ++ +IL RCP+C+ N ++ C TC P+Q+ F+ V+ + + +E IS+V +++ E++ + Y SC V P A LMCG + C+P +WF ++G +N + PFQI Y+ +H P F N C+ V+ P CSC+DC+ +C E + + + G+D IMA +F+VG ++FL + S + S++ F + DG+D + D P + N S ++ GA E +L FFT WGT+ A P +I S+ + L GI ++ +TTDP++LWASP+S+SR+ER+FFD F PFYR+ Q+I+KA NL ++ G +FGP+F +E FL +L+LQ+ I+ I NG LKDIC+A P ++ G PV P LGGF+P + + + A+A++++ ++ N+ HN + LE AL WEK + YMDIAFTSERSIEDEL +E+ D+ TI VSY+IMF+YI SLG +KR ++SKITLG+GGVIIVL SV +S+G+FG+I +PATLII E+IPFLVLAVG DNIFI+VQT QRD R ET + VGRI+G+V PSMLLTS++ES CFFLG +SDMPAVRAFALYAG+AL+IDFL+Q+TCF+SL +LD R+ +N DI C ++G K + EG++YK F Y PF+MK+ VRA+V++IFF W C S+A+ PRI++GLDQ+L+MP DSFVL YF + + L++GPPVYFV+ ++ + QN C G C+D+S+ + I L S+ +TYIA PA SWIDDY W SCCKYR C H++ N +KN +L E F KY F+ ++ D D+C K G A+ G YS S H + + E+ F Y+ I A F+ + K + + L+ R +S NG + V+VFPYS+FYVFYEQYLTMWSDT+ S+ +S LSI +VTF+L GFD +++++V+ I MI++NL G+MY+WNISLNAVSLVNLVMAVGISVEFCSH+ +F S ++I RA S
Sbjct: 34 VWYGVCNTNDFSHSQ-----NCPYNGTAKEMATDGLELLKKRCGFLLENSENKFCCDKNQVELLNKNVELAGNILDRCPSCMENLVRHICQFTCSPKQAEFMH--VVATQKNKKGDEY--ISSVDLHISTEYINKTYKSCSQVSVPQTGQLAFDLMCGAYSASRCNPTKWFNFMGDATNPYVPFQITYI-----QHEPKSNSNNFTPLNVTTVPCNQAVSSKLPACSCSDCDLSCPQGPPEPPRPEPFKIVGLDAYFVIMAAVFLVGVLVFL---MGSFLFTQGSSMDDNFQV-DGND-VSDEMPYSENDS------------------------------YFEKLGAHTETFLETFFTKWGTYFASNPGLTLIAGASLVVILGYGINFIEITTDPVKLWASPNSKSRLEREFFDTKFSPFYRLEQIIIKAVNLPQIVHNTSNGP-YTFGPVFDRE-FLTKVLDLQEGIKEINA--NGTQLKDICYAPLSDDGSEIDVSQCVVQSIWGYFGDDRERLDDHDEDNGFNVTYLDALYDCISNPYLCLAPYGGPVDPAIALGGFLPPGDQLTGSTKFELANAIILTFLVKNH-HNKTD------LENALTWEKKFVEFMTNYTKNNMSQYMDIAFTSERSIEDELNRESQSDVLTILVSYLIMFMYIAISLGHVKEFKRVFIDSKITLGIGGVIIVLASVVSSVGVFGYIGLPATLIIVEVIPFLVLAVGVDNIFILVQTHQRDQRKPNETLEQQVGRILGKVGPSMLLTSLSESFCFFLGGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRREENRMDICCFIKGKKPD-SITSNEGLLYKFFSSVYVPFLMKKIVRASVMVIFFAWLCFSIAIAPRIDIGLDQELAMPQDSFVLHYFQSLNENLNIGPPVYFVL-KGDLAYTNSSDQNLVCAGQYCNDDSVLTQIYLASRHSNQTYIARPASSWIDDYFDWAAAASSCCKYRKDSGDFCP--------------------------------------HQDTSCLRCNITKNSLLRPEEKEFVKYLPFFLKDNPD-----------------DTCAKA------------GHAAY------------------GGAVRYSNS-----HERLNIEASYFMAYHTILKSSADYFLALESARKISANITQMLQ-GRLMS-------NGVPMASALTVEVFPYSVFYVFYEQYLTMWSDTLQSMGISVLSIFVVTFVLMGFDVHSALVVVITITMIVVNLGGLMYYWNISLNAVSLVNLVMAVGISVEFCSHLVHSFATSKSVSQIDRAADS 1199
BLAST of EMLSAG00000001950 vs. Select Arthropod Genomes
Match: ADV37019.1 (Niemann-Pick type C-1a, isoform B [Drosophila melanogaster]) HSP 1 Score: 829.706 bits (2142), Expect = 0.000e+0 Identity = 501/1326 (37.78%), Postives = 713/1326 (53.77%), Query Frame = 0
Query: 21 IWFENCSQSPYLENNADKWLNCAYDGEAKEAP---LLKLERICPHL--DPSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQF--YNTVVESCDVGVNGSEP-CSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNL---FMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENGITLKDICHA-----------------------------------------------------PLEPISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAY--------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAW-TIDDSCCKYRAVDMSVCQSNGESKAKAQSALSFIDKFFENDDFFGGNSVNDFDDYDHEEEEKEESNSSKNGVL--PESMFSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNES--FFQYNVI----ASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
+W+ C+ + + + NC Y+G AKE L L++ C L + CC + Q++++ KN ++ +IL RCP+C+ N ++ C TC P+Q+ F+ V+ + + +E IS+V +++ E++ + Y SC V P A LMCG + C+P +WF ++G +N + PFQI Y+ +H P F N C+ V+ P CSC+DC+ +C E + + + G+D IMA +F+VG ++FL + S + S++ F + DG+D + D P + N S ++ GA E +L FFT WGT+ A P +I S+ + L GI ++ +TTDP++LWASP+S+SR+ER+FFD F PFYR+ Q+I+KA NL ++ G +FGP+F +E FL +L+LQ+ I+ I NG LKDIC+A P ++ G PV P LGGF+P + + + A+A++++ ++ N+ HN + LE AL WEK + YMDIAFTSERSIEDEL +E+ D+ TI VSY+IMF+YI SLG +KR ++SKITLG+GGVIIVL SV +S+G+FG+I +PATLII E+IPFLVLAVG DNIFI+VQT QRD R ET + VGRI+G+V PSMLLTS++ES CFFLG +SDMPAVRAFALYAG+AL+IDFL+Q+TCF+SL +LD R+ +N DI C ++G K + EG++YK F Y PF+MK+ VRA+V++IFF W C S+A+ PRI++GLDQ+L+MP DSFVL YF + + L++GPPVYFV+ ++ + QN C G C+D+S+ + I L S+ +TYIA PA SWIDDY W SCCKYR C H++ N +KN +L E F KY F+ ++ D D+C K G A+ G YS S H + + E+ F Y+ I A F+ + K + + L+ R +S NG + V+VFPYS+FYVFYEQYLTMWSDT+ S+ +S LSI +VTF+L GFD +++++V+ I MI++NL G+MY+WNISLNAVSLVNLVMAVGISVEFCSH+ +F S ++I RA S
Sbjct: 34 VWYGVCNTNDFSHSQ-----NCPYNGTAKEMATDGLELLKKRCGFLLENSENKFCCDKNQVELLNKNVELAGNILDRCPSCMENLVRHICQFTCSPKQAEFMH--VVATQKNKKGDEY--ISSVDLHISTEYINKTYKSCSQVSVPQTGQLAFDLMCGAYSASRCNPTKWFNFMGDATNPYVPFQITYI-----QHEPKSNSNNFTPLNVTTVPCNQAVSSKLPACSCSDCDLSCPQGPPEPPRPEPFKIVGLDAYFVIMAAVFLVGVLVFL---MGSFLFTQGSSMDDNFQV-DGND-VSDEMPYSENDS------------------------------YFEKLGAHTETFLETFFTKWGTYFASNPGLTLIAGASLVVILGYGINFIEITTDPVKLWASPNSKSRLEREFFDTKFSPFYRLEQIIIKAVNLPQIVHNTSNGP-YTFGPVFDRE-FLTKVLDLQEGIKEINA--NGTQLKDICYAPLSDDGSEIDVSQCVVQSIWGYFGDDRERLDDHDEDNGFNVTYLDALYDCISNPYLCLAPYGGPVDPAIALGGFLPPGDQLTGSTKFELANAIILTFLVKNH-HNKTD------LENALTWEKKFVEFMTNYTKNNMSQYMDIAFTSERSIEDELNRESQSDVLTILVSYLIMFMYIAISLGHVKEFKRVFIDSKITLGIGGVIIVLASVVSSVGVFGYIGLPATLIIVEVIPFLVLAVGVDNIFILVQTHQRDQRKPNETLEQQVGRILGKVGPSMLLTSLSESFCFFLGGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRREENRMDICCFIKGKKPD-SITSNEGLLYKFFSSVYVPFLMKKIVRASVMVIFFAWLCFSIAIAPRIDIGLDQELAMPQDSFVLHYFQSLNENLNIGPPVYFVL-KGDLAYTNSSDQNLVCAGQYCNDDSVLTQIYLASRHSNQTYIARPASSWIDDYFDWAAAASSCCKYRKDSGDFCP--------------------------------------HQDTSCLRCNITKNSLLRPEEKEFVKYLPFFLKDNPD-----------------DTCAKA------------GHAAY------------------GGAVRYSNS-----HERLNIEASYFMAYHTILKSSADYFLALESARKISANITQMLQ-GRLMS-------NGVPMASALTVEVFPYSVFYVFYEQYLTMWSDTLQSMGISVLSIFVVTFVLMGFDVHSALVVVITITMIVVNLGGLMYYWNISLNAVSLVNLVMAVGISVEFCSHLVHSFATSKSVSQIDRAADS 1199
BLAST of EMLSAG00000001950 vs. Select Arthropod Genomes
Match: AAF52874.2 (Niemann-Pick type C-1a, isoform A [Drosophila melanogaster]) HSP 1 Score: 829.706 bits (2142), Expect = 0.000e+0 Identity = 501/1326 (37.78%), Postives = 713/1326 (53.77%), Query Frame = 0
Query: 21 IWFENCSQSPYLENNADKWLNCAYDGEAKEAP---LLKLERICPHL--DPSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQF--YNTVVESCDVGVNGSEP-CSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNL---FMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENGITLKDICHA-----------------------------------------------------PLEPISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAY--------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAW-TIDDSCCKYRAVDMSVCQSNGESKAKAQSALSFIDKFFENDDFFGGNSVNDFDDYDHEEEEKEESNSSKNGVL--PESMFSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNES--FFQYNVI----ASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
+W+ C+ + + + NC Y+G AKE L L++ C L + CC + Q++++ KN ++ +IL RCP+C+ N ++ C TC P+Q+ F+ V+ + + +E IS+V +++ E++ + Y SC V P A LMCG + C+P +WF ++G +N + PFQI Y+ +H P F N C+ V+ P CSC+DC+ +C E + + + G+D IMA +F+VG ++FL + S + S++ F + DG+D + D P + N S ++ GA E +L FFT WGT+ A P +I S+ + L GI ++ +TTDP++LWASP+S+SR+ER+FFD F PFYR+ Q+I+KA NL ++ G +FGP+F +E FL +L+LQ+ I+ I NG LKDIC+A P ++ G PV P LGGF+P + + + A+A++++ ++ N+ HN + LE AL WEK + YMDIAFTSERSIEDEL +E+ D+ TI VSY+IMF+YI SLG +KR ++SKITLG+GGVIIVL SV +S+G+FG+I +PATLII E+IPFLVLAVG DNIFI+VQT QRD R ET + VGRI+G+V PSMLLTS++ES CFFLG +SDMPAVRAFALYAG+AL+IDFL+Q+TCF+SL +LD R+ +N DI C ++G K + EG++YK F Y PF+MK+ VRA+V++IFF W C S+A+ PRI++GLDQ+L+MP DSFVL YF + + L++GPPVYFV+ ++ + QN C G C+D+S+ + I L S+ +TYIA PA SWIDDY W SCCKYR C H++ N +KN +L E F KY F+ ++ D D+C K G A+ G YS S H + + E+ F Y+ I A F+ + K + + L+ R +S NG + V+VFPYS+FYVFYEQYLTMWSDT+ S+ +S LSI +VTF+L GFD +++++V+ I MI++NL G+MY+WNISLNAVSLVNLVMAVGISVEFCSH+ +F S ++I RA S
Sbjct: 34 VWYGVCNTNDFSHSQ-----NCPYNGTAKEMATDGLELLKKRCGFLLENSENKFCCDKNQVELLNKNVELAGNILDRCPSCMENLVRHICQFTCSPKQAEFMH--VVATQKNKKGDEY--ISSVDLHISTEYINKTYKSCSQVSVPQTGQLAFDLMCGAYSASRCNPTKWFNFMGDATNPYVPFQITYI-----QHEPKSNSNNFTPLNVTTVPCNQAVSSKLPACSCSDCDLSCPQGPPEPPRPEPFKIVGLDAYFVIMAAVFLVGVLVFL---MGSFLFTQGSSMDDNFQV-DGND-VSDEMPYSENDS------------------------------YFEKLGAHTETFLETFFTKWGTYFASNPGLTLIAGASLVVILGYGINFIEITTDPVKLWASPNSKSRLEREFFDTKFSPFYRLEQIIIKAVNLPQIVHNTSNGP-YTFGPVFDRE-FLTKVLDLQEGIKEINA--NGTQLKDICYAPLSDDGSEIDVSQCVVQSIWGYFGDDRERLDDHDEDNGFNVTYLDALYDCISNPYLCLAPYGGPVDPAIALGGFLPPGDQLTGSTKFELANAIILTFLVKNH-HNKTD------LENALTWEKKFVEFMTNYTKNNMSQYMDIAFTSERSIEDELNRESQSDVLTILVSYLIMFMYIAISLGHVKEFKRVFIDSKITLGIGGVIIVLASVVSSVGVFGYIGLPATLIIVEVIPFLVLAVGVDNIFILVQTHQRDQRKPNETLEQQVGRILGKVGPSMLLTSLSESFCFFLGGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRREENRMDICCFIKGKKPD-SITSNEGLLYKFFSSVYVPFLMKKIVRASVMVIFFAWLCFSIAIAPRIDIGLDQELAMPQDSFVLHYFQSLNENLNIGPPVYFVL-KGDLAYTNSSDQNLVCAGQYCNDDSVLTQIYLASRHSNQTYIARPASSWIDDYFDWAAAASSCCKYRKDSGDFCP--------------------------------------HQDTSCLRCNITKNSLLRPEEKEFVKYLPFFLKDNPD-----------------DTCAKA------------GHAAY------------------GGAVRYSNS-----HERLNIEASYFMAYHTILKSSADYFLALESARKISANITQMLQ-GRLMS-------NGVPMASALTVEVFPYSVFYVFYEQYLTMWSDTLQSMGISVLSIFVVTFVLMGFDVHSALVVVITITMIVVNLGGLMYYWNISLNAVSLVNLVMAVGISVEFCSHLVHSFATSKSVSQIDRAADS 1199
BLAST of EMLSAG00000001950 vs. Select Arthropod Genomes
Match: EEB17553.1 (Niemann-Pick C1 protein precursor, putative [Pediculus humanus corporis]) HSP 1 Score: 806.594 bits (2082), Expect = 0.000e+0 Identity = 494/1307 (37.80%), Postives = 708/1307 (54.17%), Query Frame = 0
Query: 36 ADKWLNCAYDGEAK---EAPLLKLERICPHLDPSEG------VCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQG-QVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPI-PEGIQFYNTVVESC-DVGVNGSEPCSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENGITLKDICHAPL--------------------------------------------------EPISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEE--------IKKLEKALEWEKAYYMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTIDDSCCKYRAVDMSVCQSNGESKAKAQSALSFIDKFFENDDFFGGNSVNDFDDYDHEEEEKEESNSSKNGVLPESM-FSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKC--PNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDK--SQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTSHQSTQDGN 1267
A + L C+Y+G AK + + L++ CPH S CC E QL+ ++KN + ++ RCP+C +NF +++C TC P QS F++ +++ + ++ +S + Y+ + YDSCK V P + A+ L+C + CSP WF +LG S F+P+QI+Y+ S + + P I+ Y SC + + CSC DC +C P + V + V + G F+M ++F+ G +IFL+IV+ Q G+ E +++T V SL+ I++AGA +E +L FF G C P V++ L + I L GI ++ VTTDPIELWA+P SRSRVE++++D FRPFYR Q+I+ A L + ++ LG +FGP+F+ FL + +L+++I N+ +G+TLKDIC +PL E ++ G P+ P LGGF+ P Y ++ ++++ +++N+ HN E I+ L+ E EK YMD+A++SERSIEDEL + ++ D+ TI +SY+IMF YI SLG+ ++ R + +SK+TLGLGGV++VL+SVA S+GIFG+I VPATLII E+IPFLVLAVG DNIFI+VQT R PR E+ EH+GR +G V PSM LTS++ES CFFLG +S+MPAVRAFALYAGMALLIDF+ QVTCF+SL++LD RQ YD+ C ++ SKK+ G++YK FK+ Y P +M + VR VV++F+ W C S+AV PRI+VGLDQ+LSM DS+VLKYF ++ YLS+GPPVYFVV +N++ S P IQN FC G C +SL + + L SKQ +YIA PA SW+DDY W D CC F N+ F + YD E +E + G+ P S F +Y F+ +D D SC K P+ A++ + G ++ N ER + + Y+ I +++ L++ AR +++ I +SIN LT + V+VFPYS+FYVFYEQYLT+W D INS+L+SFL+I + +F+L G D + +IV+ IAMILINL G+MY+W+I LNAVSLVNLVMAVGI+VEFCSH+ +FT S E K+ RA SH T G+
Sbjct: 13 AAQLLPCSYNGTAKVLSDKGIKVLKKWCPHYFDSTSDSQLIYTCCDEAQLETLDKNIQQAMMLISRCPSCKYNFVRHYCDFTCRPDQSNFIEPLRIVNATLNKSAGYRPAVSEINLYINKSYTYGTYDSCKNVYLPLANQYAMDLLCNRPVVS-CSPELWFEFLGDAS-AFSPYQINYIMSSKAKEKNFTPLNIKTY-----SCNEAPLENESACSCVDCVESCPIPPPVPSPVAPFFVGALPGRDFVMLLVFIAGSLIFLSIVLFCNKRNRQ---------------------QGASEGNPNEKTE-----------FVGTKSSLSKIEKAGAAIEKFLERFFYKLGMLCVSRPWLVLLTGLLVFICLACGILFVKVTTDPIELWANPLSRSRVEKEYYDSNFRPFYRTEQIIIHAVGLPNITHNTSLGPV-TFGPVFNVS-FLKKIYDLEQSIRNLNA--DGVTLKDICFSPLSSDSGPEDVSQCSIMSIWGYYQDDLSNLDTEDDEYLNRFMSCVNNPYLPDECLAPWGGPILPDLALGGFLEAGLNEKGKPKYELSTTLILTYLVDNH-HNKTLREPALKWEARFIELLKNWTETEKPDYMDVAYSSERSIEDELERTSHSDVGTILISYLIMFAYIAISLGQIRSFSRLLTDSKMTLGLGGVLVVLISVACSVGIFGYIGVPATLIIIEVIPFLVLAVGVDNIFILVQTHNRLPREPNESLEEHIGRTLGVVGPSMTLTSLSESFCFFLGGLSNMPAVRAFALYAGMALLIDFIFQVTCFVSLLALDSRRQTAGRYDVCCFIKSSKKDSGSALPNGLLYKFFKNIYVPALMNKIVRPLVVVVFYAWLCLSIAVLPRIQVGLDQELSMSQDSYVLKYFKSLKSYLSIGPPVYFVVKDTNLNYSKPEIQNLFCTGPKCHLDSLTTQVYLASKQANSSYIATPASSWLDDYFDWLSYDKCC-----------------------------FVTNNKSFCPH----ISPYDCETCPRENA----TGIRPSSTDFERYLSFFLKDDPD-----------------ASCAKGGHPSYGPAVNYRNLG-----------VDKNGFER------------------SMASSNYYMAYHTILKTSEDYYSALRS----------ARDIAANITSSINDRLTKMGGNASVEVFPYSVFYVFYEQYLTVWEDGINSMLISFLAIFVTSFVLLGLDLCGAFVIVITIAMILINLGGLMYWWDIGLNAVSLVNLVMAVGIAVEFCSHLVHSFTSSTESNKLQRA--SHALTDMGS 1180
BLAST of EMLSAG00000001950 vs. Select Arthropod Genomes
Match: gb|KYB26045.1| (Niemann-Pick C1 protein-like Protein [Tribolium castaneum]) HSP 1 Score: 727.243 bits (1876), Expect = 0.000e+0 Identity = 409/1004 (40.74%), Postives = 574/1004 (57.17%), Query Frame = 0
Query: 21 IWFENCSQSPYLENNADKWLNCAYDGEAK----EAPLLKLERICPHL--DPSEGV--CCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSL--SNGFTPFQIDYVFSGETRHHPI-PEGIQF--YNTVVESCDVGVNG-SEPCSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENGITLKDICHAPLEPISDGGIPVQP---YYMLGGFIPENEPF------------------------PQNP------------------------------SYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAY--------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAW-TIDDSCCKYRAVDMSVC 938
+W+ C+ SP ++ C YDG K L L + CPHL D S+ + CC Q+ N ++A+ L RCP+C+ N ++ C TC Q+ +++ + +N + V I+ + ++ +++++ Y SCK V PS AL LMCG WG CS RWF ++G+ +N F PFQI+Y+ S P+ +G+++ N + C+ + S CSC DCE +C P + + + G DG F+M I+F VG ++FL +V V P+ +E TS+ + H ++ K + S + +++ GA+ + +L FF +WGT CA+ P V+ + + +GL GI +L VTTDP+ELWASP+SRSR+E+++FD F PFYR QVI+KA NL ++ GE FGP F FL +L+LQ+ I+ I + L IC APL + V+ + G + + E F P NP +Y A+AV+++ ++NNY HN KL A+EWEKA+ YM+IAFTSERSIEDEL +E+ D+ TI VSYIIMF YI SLG+ T R +++SKITLGLGGV+IVL SV +S+G+FGF+ +PATLII E+IPFLVLAVG DNIFI+VQT QR+ + TETH +H+GR +G+V PSMLLTSV+ES CFFLG++SDMPAV+AFALYAGMALL DFL+Q+TCF+SL+SLD RQ N +DI C ++GSKK + Q EG++Y FK Y P +M +VRA V+I+FFGW C+S+AV P IE+GLDQ+LSMP+DS+VLKYF F++ LS+GPP+YFVV ++ S P QN CGG C +SL + + SK PE+TYIA P+ SW+DDY+ W +CCKY + C
Sbjct: 44 VWYGECNTSP---TGLTQY--CPYDGPPKPLNDTTALETLSKWCPHLISDSSQTINACCDAAQVATFATNIQLAANFLKRCPSCMMNLARHLCDFTCGQDQTNYMKIVEVKNN----TKGVEYITAIDLFITNDYLEGTYKSCKQVSVPSSGQLALDLMCGSWGASKCSAMRWFNFMGTAGDTNPFVPFQINYLNST----GPVDKDGVKYQPLNPEITPCNKAFDSKSAACSCVDCEESCPVPPPQPPAPQPFTIAGFDGYFFLMIIVFCVGTLMFLLVVF--------------------------VCPSRAEIGVTSEMGHELDTHSIN-KMPGEYESSSSFLEKLGANTDTFLQRFFEWWGTICAERPWLVLFLGACVVVGLGHGIKYLKVTTDPVELWASPTSRSRIEKEYFDSHFEPFYRNEQVIIKAVNLPQIHHNTSNGEV-VFGPAF-DATFLKEVLKLQERIKAIGA-DTDYALGRICFAPLRSVGKVSTDVEECVVQSIWGYYQNDEETFDETDVDPDGFETNYLDYFISCAQNPYNPKCLAPYGGPVDPAIAMGGFLQPGENLSKQPNYQNATAVILTFLVNNY-HNK------TKLSPAMEWEKAFVAFMKNYTTSEKPSYMEIAFTSERSIEDELDRESQSDVVTILVSYIIMFAYIAVSLGQVNTCSRLLIDSKITLGLGGVLIVLASVVSSVGLFGFVGLPATLIIIEVIPFLVLAVGVDNIFILVQTHQREGKKPTETHAQHIGRTLGQVGPSMLLTSVSESCCFFLGSLSDMPAVKAFALYAGMALLFDFLLQITCFVSLLSLDTIRQASNRFDICCFIKGSKKEIVQTNQEGLLYSFFKSIYVPLLMNRFVRAFVMIVFFGWLCSSIAVVPHIEIGLDQELSMPEDSYVLKYFKFLKDDLSIGPPMYFVV-KDGLNYSDPKAQNVICGGQYCDLDSLITQVFEASKVPERTYIARPSSSWLDDYIDWAAAAKTCCKYNKTTGAFC 996 HSP 2 Score: 241.121 bits (614), Expect = 8.653e-64 Identity = 116/214 (54.21%), Postives = 156/214 (72.90%), Query Frame = 0
Query: 1046 RPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
RP P F Y+ +FL+DNP E C KAGHAAYSQ V N++ V AS FM +HTILKT KDYYE++R AR++S+ I N+IN + S ++VFPYS+FYVFYEQYLTMW DT+ S+ +S +I +VTF+L G DF +S ++V+ I MI++NL G+MY+W+I+LNAVSLVNLVMAVGI+VEFCSH+ +F+ S++ T++ RA S
Sbjct: 1016 RPTPNDFEHYVSFFLQDNPDETCAKAGHAAYSQGVNYAT-----NKTTHLSKVGASYFMAYHTILKTSKDYYESMRSARKVSANITNTINTKI--PSSQIEVFPYSVFYVFYEQYLTMWPDTLQSMAISLAAIFVVTFLLMGLDFFSSAVVVITITMIVVNLGGLMYWWHITLNAVSLVNLVMAVGIAVEFCSHLVHSFSVSLKTTRVERAADS 1222
BLAST of EMLSAG00000001950 vs. Select Arthropod Genomes
Match: gb|EFA11848.2| (Niemann-Pick C1 protein-like Protein [Tribolium castaneum]) HSP 1 Score: 726.087 bits (1873), Expect = 0.000e+0 Identity = 414/1026 (40.35%), Postives = 584/1026 (56.92%), Query Frame = 0
Query: 21 IWFENCSQSPYLENNADKWLNCAYDGEAK----EAPLLKLERICPHL--DPSEGV--CCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSL--SNGFTPFQIDYVFSGETRHHPI-PEGIQF--YNTVVESCDVGVNG-SEPCSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDS-------------IYDGTPVTPNGSEESTTSQQTNGSS-----NHEVDA----KGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENGITLKDICHAPLEPISDGGIPVQP---YYMLGGFIPENEPF------------------------PQNP------------------------------SYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAY--------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAW-TIDDSCCKYRAVDMSVC 938
+W+ C+ SP ++ C YDG K L L + CPHL D S+ + CC Q+ N ++A+ L RCP+C+ N ++ C TC Q+ +++ + +N + V I+ + ++ +++++ Y SCK V PS AL LMCG WG CS RWF ++G+ +N F PFQI+Y+ S P+ +G+++ N + C+ + S CSC DCE +C P + + + G DG F+M I+F VG ++FL +V + +++ + L G S + + + EE + Q + SS HE+D K + S + +++ GA+ + +L FF +WGT CA+ P V+ + + +GL GI +L VTTDP+ELWASP+SRSR+E+++FD F PFYR QVI+KA NL ++ GE FGP F FL +L+LQ+ I+ I + L IC APL + V+ + G + + E F P NP +Y A+AV+++ ++NNY HN KL A+EWEKA+ YM+IAFTSERSIEDEL +E+ D+ TI VSYIIMF YI SLG+ T R +++SKITLGLGGV+IVL SV +S+G+FGF+ +PATLII E+IPFLVLAVG DNIFI+VQT QR+ + TETH +H+GR +G+V PSMLLTSV+ES CFFLG++SDMPAV+AFALYAGMALL DFL+Q+TCF+SL+SLD RQ N +DI C ++GSKK + Q EG++Y FK Y P +M +VRA V+I+FFGW C+S+AV P IE+GLDQ+LSMP+DS+VLKYF F++ LS+GPP+YFVV ++ S P QN CGG C +SL + + SK PE+TYIA P+ SW+DDY+ W +CCKY + C
Sbjct: 44 VWYGECNTSP---TGLTQY--CPYDGPPKPLNDTTALETLSKWCPHLISDSSQTINACCDAAQVATFATNIQLAANFLKRCPSCMMNLARHLCDFTCGQDQTNYMKIVEVKNN----TKGVEYITAIDLFITNDYLEGTYKSCKQVSVPSSGQLALDLMCGSWGASKCSAMRWFNFMGTAGDTNPFVPFQINYLNST----GPVDKDGVKYQPLNPEITPCNKAFDSKSAACSCVDCEESCPVPPPQPPAPQPFTIAGFDGYFFLMIIVFCVGTLMFLLVVF---VCPSRAEIVGLVTGHGSEEMRAAVGRRLAGVDRQSRLVLGSDEEDSPLQDSKRSSVTSEMGHELDTHSINKMPGEYESSSSFLEKLGANTDTFLQRFFEWWGTICAERPWLVLFLGACVVVGLGHGIKYLKVTTDPVELWASPTSRSRIEKEYFDSHFEPFYRNEQVIIKAVNLPQIHHNTSNGEV-VFGPAF-DATFLKEVLKLQERIKAIGA-DTDYALGRICFAPLRSVGKVSTDVEECVVQSIWGYYQNDEETFDETDVDPDGFETNYLDYFISCAQNPYNPKCLAPYGGPVDPAIAMGGFLQPGENLSKQPNYQNATAVILTFLVNNY-HNK------TKLSPAMEWEKAFVAFMKNYTTSEKPSYMEIAFTSERSIEDELDRESQSDVVTILVSYIIMFAYIAVSLGQVNTCSRLLIDSKITLGLGGVLIVLASVVSSVGLFGFVGLPATLIIIEVIPFLVLAVGVDNIFILVQTHQREGKKPTETHAQHIGRTLGQVGPSMLLTSVSESCCFFLGSLSDMPAVKAFALYAGMALLFDFLLQITCFVSLLSLDTIRQASNRFDICCFIKGSKKEIVQTNQEGLLYSFFKSIYVPLLMNRFVRAFVMIVFFGWLCSSIAVVPHIEIGLDQELSMPEDSYVLKYFKFLKDDLSIGPPMYFVV-KDGLNYSDPKAQNVICGGQYCDLDSLITQVFEASKVPERTYIARPSSSWLDDYIDWAAAAKTCCKYNKTTGAFC 1042 HSP 2 Score: 241.121 bits (614), Expect = 8.541e-64 Identity = 116/214 (54.21%), Postives = 156/214 (72.90%), Query Frame = 0
Query: 1046 RPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
RP P F Y+ +FL+DNP E C KAGHAAYSQ V N++ V AS FM +HTILKT KDYYE++R AR++S+ I N+IN + S ++VFPYS+FYVFYEQYLTMW DT+ S+ +S +I +VTF+L G DF +S ++V+ I MI++NL G+MY+W+I+LNAVSLVNLVMAVGI+VEFCSH+ +F+ S++ T++ RA S
Sbjct: 1062 RPTPNDFEHYVSFFLQDNPDETCAKAGHAAYSQGVNYAT-----NKTTHLSKVGASYFMAYHTILKTSKDYYESMRSARKVSANITNTINTKI--PSSQIEVFPYSVFYVFYEQYLTMWPDTLQSMAISLAAIFVVTFLLMGLDFFSSAVVVITITMIVVNLGGLMYWWHITLNAVSLVNLVMAVGIAVEFCSHLVHSFSVSLKTTRVERAADS 1268
BLAST of EMLSAG00000001950 vs. nr
Match: gi|1036925418|ref|XP_017095810.1| (PREDICTED: Niemann-Pick C1 protein isoform X1 [Drosophila bipectinata] >gi|1036925435|ref|XP_017095811.1| PREDICTED: Niemann-Pick C1 protein isoform X1 [Drosophila bipectinata] >gi|1036925467|ref|XP_017095813.1| PREDICTED: Niemann-Pick C1 protein isoform X1 [Drosophila bipectinata]) HSP 1 Score: 880.552 bits (2274), Expect = 0.000e+0 Identity = 528/1343 (39.31%), Postives = 732/1343 (54.50%), Query Frame = 0
Query: 1 MYGFVLFIVGALLKVACGRXIWFENCSQSPYLENNADKWLNCAYDGEAKEAP-----LLKLERICPHLDPSEG-VCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQF--YNTVVESCDVGVNGSEP-CSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENGITLKDICHAPL-----------------------------EPISDGGI------------------------PVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAY--------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTIDDSCCKYRAVDMSVCQSNGESKAKAQSALSFIDKFFENDDFFGGNSVNDFDDYDHEEEEKEESNSSKNGVL--PESMFSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLT------DKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
++ VL + L K C +W+ C+ + Y + NC Y+G A E P LLK ER L +E CC +Q+ ++ KN ++A+ L RCP+C+ N ++ C TC P+QS F+ N + IS V +V+ E++ + Y SC V P A LMCG + C+P +WF ++G S+ + PFQI Y+ +H P + +F + C+ VN P CSC+DC+ +C E + + G+D + IMA +F+VG ++FL + S + S+L D + I DG VT + + S ++ GA E +L +FFT WGTF A P ++ + L G+ +N+TTDP++LWASP S+SR+ER+FFD F PFYR+ Q+I+KA +L ++ G +FGP+F +E FL +L LQ++I+ K NG TLKDIC APL + DGG PV P LGGF+ + N Y A+A++++ ++ N+ HN + L KAL+WEK + +MDIAFTSERSIEDEL +E+ D+ TI VSY+IMF+YI SLG +KR ++SKITLG+GGVIIVL SV +S+G+FG++ VPATLII E+IPFLVLAVG DNIFI+VQT QRD R ET + VGRI+G V PSMLLTS++ES CFFLG +SDMPAVRAFALYAG+AL+IDFL+Q+TCF+SL +LD R+ +N DI C V+G K + N EG++YK FK Y PF+MK+ VR AV++IFF W C S+A+ P+I++GLDQ+L+MP+DSFVL YF + + L++GPPVYFV+ ++ + +QN C G C+D+S+ + I L S+ +TYIA PA SW+DDY W+ SCCKY + S C H++ N SKN + E F KY F+ ++ D DSC K AGHAAY +VR A+ +K NV AS FM +HTILKT DY+ AL AR++S+ I + G L + + V+VFPYS+FYVFYEQYLTMWSDT+ S+ +S LSI +VTF+L GFD +++++V+ I MI++NL G+MY+WNISLNAVSLVNLVMAVGISVEFCSH+ +F+ S ++I RA S
Sbjct: 17 LFSVVLLTLIQLSKQDC---VWYGVCNTNVYGHSQ-----NCPYNGSAIEMPQAGLDLLK-ERCGFLLQNNENKYCCDTEQVQILNKNVKLAANFLDRCPSCMENLVRHICEFTCSPKQSEFIHVAATEKNGSTGRP---YISAVDLHVSTEYINKTYKSCSQVSVPQTGQLAFDLMCGSYPASRCNPTKWFNFMGDASSPYVPFQITYI-----QHEPKSKSNEFKPLSPPTIPCNQSVNSKLPACSCSDCDMSCPQGPPEPPPPEPFKIFGLDAYLVIMAAVFLVGVLVFL---MGSFLFTQGSSL----DENFQI-DGNDVTDDMAYREDDS------------------------YFEKLGARTETFLEHFFTKWGTFFASNPWMTLVAGACLVCVLGYGVSHINITTDPVKLWASPKSKSRLEREFFDTKFEPFYRLEQIIIKAVDLPQIVHNTSNGPI-TFGPVFDRE-FLTNVLHLQESIK--KLNANGTTLKDICFAPLSEDGNALEDSNCVVQSIWGYFQDDIERLDDNDEDGGFNVTYLDELYQCTSNPYLCLAPYGGPVDPAIALGGFLRAGDQLTGNTKYELANALILTFLVKNH-HNKTD------LRKALQWEKMFVEFMTNYTSHNKSKHMDIAFTSERSIEDELNRESQSDVLTILVSYLIMFMYIAISLGHVKEFKRVFIDSKITLGIGGVIIVLASVVSSVGLFGYVGVPATLIIVEVIPFLVLAVGVDNIFILVQTHQRDQRKPNETLEQQVGRILGRVGPSMLLTSLSESFCFFLGGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRKEENRMDICCFVKGKKSDSIDN-SEGLLYKFFKSVYVPFLMKKIVRVAVMVIFFAWLCFSIAIAPKIDIGLDQELAMPEDSFVLHYFQSLNENLNIGPPVYFVL-KGDLSYTNSSVQNLVCAGRYCNDDSVLTQIYLASRHSNQTYIARPASSWLDDYFDWSSTQSCCKYNPSNGSFCP--------------------------------------HQDTSCSNCNISKNSLQRPDEKSFEKYLPFFLKDNPD-----------------DSCAK------------------------------------AGHAAYGSAVRY-ANGKKG------LNVEASYFMGYHTILKTSADYFLALESARKISANITQMLQGRLMSNGVPIESALTVEVFPYSVFYVFYEQYLTMWSDTLQSMGISVLSIFVVTFVLMGFDVHSALVVVITITMIVVNLGGLMYYWNISLNAVSLVNLVMAVGISVEFCSHLVHSFSISKSVSQIDRAADS 1199
BLAST of EMLSAG00000001950 vs. nr
Match: gi|964109256|ref|XP_014761453.1| (uncharacterized protein Dana_GF14130, isoform B [Drosophila ananassae] >gi|939216167|gb|KPU73871.1| uncharacterized protein Dana_GF14130, isoform B [Drosophila ananassae]) HSP 1 Score: 877.47 bits (2266), Expect = 0.000e+0 Identity = 522/1343 (38.87%), Postives = 725/1343 (53.98%), Query Frame = 0
Query: 1 MYGFVLFIVGALLKVACGRXIWFENCSQSPYLENNADKWLNCAYDGEAKEAP-----LLKLERICPHLDPSEG-VCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQF--YNTVVESCDVGVNGSEP-CSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENGITLKDICHAPL-----------------------------EPISDGGI------------------------PVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAY--------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTIDDSCCKYRAVDMSVCQSNGESKAKAQSALSFIDKFFENDDFFGGNSVNDFDDYDHEEEEKEESNSSKNGVL--PESMFSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLT------DKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
++ VLF + L K C +W+ C+ + + + NC Y+G A E P LLK ER L +E CC +Q+ ++ KN ++ + L RCP+C+ N ++ C TC P+QS F+ N + S IS V +V+ +++ + Y SC V P A LMCG + C+P +WF ++G ++ + PFQI Y+ +H P +F C+ V+ P CSC+DCE +C E + + G+D + IMA +F VG ++FL L TQ F + DG VT + + + ++ GA E +L FFT WGTF A P ++ + + L G+ +N+TTDP++LWASP+S+SR+ER+FFD F PFYR+ Q+I+KA +L ++ G +FGP+F +E FL +L LQ+ I+ K NG TLKDIC APL + DGG PV P LGGF+ + N Y A+A++++ ++ N+ HN + L +ALEWEK + +MDIAFTSERSIEDEL +E+ D+ TI VSY+IMF+YI SLG +KR ++SKITLG+GGVIIVL SV +S+G+FG+I VPATLII E+IPFLVLAVG DNIFI+VQT QRD R ET + +GRI+G V PSMLLTS++ES CFFLG +SDMPAVRAFALYAG+AL+IDFL+Q+TCF+SL +LD R+ +N DI C V+G K + N EG++YK FK Y PF+MK+ VR V++IFF W C S+A+ P+I++GLDQ+L+MP+DSFVL YF + + L++GPPVYFV+ ++ + +QN C G C+D+S+ + I L S+ +TYIA PA SW+DDY W+ SCCK+ + S C H++ N SKN + E F KY F+ ++ D DSC K AGHAAY +VR A+ +K NV AS FM +HTILKT DY+ AL AR++S+ I + G L + + V+VFPYS+FYVFYEQYLTMWSDT+ S+ +S LSI +VTF+L GFD +++++V+ I MI++NL G+MY+WNISLNAVSLVNLVMAVGISVEFCSH+ +F+ S ++I RA S
Sbjct: 17 LFSAVLFTLIQLSKQDC---VWYGVCNTNAFQHSQ-----NCPYNGTAIEMPQAGLDLLK-ERCGFLLQNNENKYCCDTEQVKILNKNVKLAGNFLDRCPSCMENLVRHICEFTCSPKQSEFMHVAATEKN----KTGGSYISAVDLHVSTDYINKTYKSCSQVSVPQTGQLAFDLMCGSYPASRCNPTKWFNFMGDATSPYVPFQITYI-----QHEPKSNSKEFKPLGPPTIPCNQAVSSELPACSCSDCEKSCPQGPPEPPPPEPFKIFGLDAYLVIMAAVFFVGVLVFLM----GSFLFTQDENFQI--------DGNDVTDDMAYRDDS-------------------------YFEKLGARTETFLEQFFTKWGTFFASNPWMTLVAGACLVVVLGYGVSHINITTDPVKLWASPNSKSRLEREFFDTKFEPFYRLEQIIIKAVDLPQIVHNTSNGPI-TFGPVFDRE-FLTNVLYLQEGIK--KLNANGTTLKDICFAPLSEDGNALEDSNCVVQSIWGYFQDDIERLDDEEEDGGFNVTYLDALFQCTSNPYLCLAPYGGPVDPAIALGGFLRAGDQLTGNTKYELANALILTFLVKNH-HNRTD------LHRALEWEKMFVEFMTNYTSHNKSKHMDIAFTSERSIEDELNRESQSDVLTILVSYLIMFMYIAISLGHVKEFKRVFIDSKITLGIGGVIIVLASVVSSVGLFGYIGVPATLIIVEVIPFLVLAVGVDNIFILVQTHQRDQRKPNETLEQQIGRILGRVGPSMLLTSLSESFCFFLGGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRKEENRMDICCFVKGKKSDSIAN-SEGLLYKFFKSVYVPFLMKKIVRVGVMVIFFAWLCFSIAIAPKIDIGLDQELAMPEDSFVLHYFQSLNENLNIGPPVYFVL-KGDLSYTNSSVQNLVCAGRYCNDDSVLTQIYLASRHSNQTYIARPASSWLDDYFDWSSTQSCCKFNPSNGSFCP--------------------------------------HQDTSCTNCNISKNSIQRPDEKSFDKYLPFFLKDNPD-----------------DSCAK------------------------------------AGHAAYGSAVRY-ANGKKG------LNVEASYFMGYHTILKTSADYFLALESARKISANITQMLQGRLMSNGVPIESALTVEVFPYSVFYVFYEQYLTMWSDTLQSMGISVLSIFVVTFVLMGFDVHSALVVVITITMIVVNLGGLMYYWNISLNAVSLVNLVMAVGISVEFCSHLVHSFSTSKSVSQIDRAADS 1193
BLAST of EMLSAG00000001950 vs. nr
Match: gi|194761678|ref|XP_001963055.1| (uncharacterized protein Dana_GF14130, isoform A [Drosophila ananassae] >gi|964109261|ref|XP_014761454.1| uncharacterized protein Dana_GF14130, isoform C [Drosophila ananassae] >gi|964109267|ref|XP_014761455.1| uncharacterized protein Dana_GF14130, isoform D [Drosophila ananassae] >gi|964109274|ref|XP_014761456.1| uncharacterized protein Dana_GF14130, isoform E [Drosophila ananassae] >gi|964109279|ref|XP_014761457.1| uncharacterized protein Dana_GF14130, isoform F [Drosophila ananassae] >gi|190616752|gb|EDV32276.1| uncharacterized protein Dana_GF14130, isoform A [Drosophila ananassae] >gi|939216168|gb|KPU73872.1| uncharacterized protein Dana_GF14130, isoform C [Drosophila ananassae] >gi|939216169|gb|KPU73873.1| uncharacterized protein Dana_GF14130, isoform D [Drosophila ananassae] >gi|939216170|gb|KPU73874.1| uncharacterized protein Dana_GF14130, isoform E [Drosophila ananassae] >gi|939216171|gb|KPU73875.1| uncharacterized protein Dana_GF14130, isoform F [Drosophila ananassae]) HSP 1 Score: 876.315 bits (2263), Expect = 0.000e+0 Identity = 523/1343 (38.94%), Postives = 729/1343 (54.28%), Query Frame = 0
Query: 1 MYGFVLFIVGALLKVACGRXIWFENCSQSPYLENNADKWLNCAYDGEAKEAP-----LLKLERICPHLDPSEG-VCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQF--YNTVVESCDVGVNGSEP-CSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENGITLKDICHAPL-----------------------------EPISDGGI------------------------PVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAY--------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTIDDSCCKYRAVDMSVCQSNGESKAKAQSALSFIDKFFENDDFFGGNSVNDFDDYDHEEEEKEESNSSKNGVL--PESMFSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLT------DKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
++ VLF + L K C +W+ C+ + + + NC Y+G A E P LLK ER L +E CC +Q+ ++ KN ++ + L RCP+C+ N ++ C TC P+QS F+ N + S IS V +V+ +++ + Y SC V P A LMCG + C+P +WF ++G ++ + PFQI Y+ +H P +F C+ V+ P CSC+DCE +C E + + G+D + IMA +F VG ++FL + S + S+L D + I DG VT + + + ++ GA E +L FFT WGTF A P ++ + + L G+ +N+TTDP++LWASP+S+SR+ER+FFD F PFYR+ Q+I+KA +L ++ G +FGP+F +E FL +L LQ+ I+ K NG TLKDIC APL + DGG PV P LGGF+ + N Y A+A++++ ++ N+ HN + L +ALEWEK + +MDIAFTSERSIEDEL +E+ D+ TI VSY+IMF+YI SLG +KR ++SKITLG+GGVIIVL SV +S+G+FG+I VPATLII E+IPFLVLAVG DNIFI+VQT QRD R ET + +GRI+G V PSMLLTS++ES CFFLG +SDMPAVRAFALYAG+AL+IDFL+Q+TCF+SL +LD R+ +N DI C V+G K + N EG++YK FK Y PF+MK+ VR V++IFF W C S+A+ P+I++GLDQ+L+MP+DSFVL YF + + L++GPPVYFV+ ++ + +QN C G C+D+S+ + I L S+ +TYIA PA SW+DDY W+ SCCK+ + S C H++ N SKN + E F KY F+ ++ D DSC K AGHAAY +VR A+ +K NV AS FM +HTILKT DY+ AL AR++S+ I + G L + + V+VFPYS+FYVFYEQYLTMWSDT+ S+ +S LSI +VTF+L GFD +++++V+ I MI++NL G+MY+WNISLNAVSLVNLVMAVGISVEFCSH+ +F+ S ++I RA S
Sbjct: 17 LFSAVLFTLIQLSKQDC---VWYGVCNTNAFQHSQ-----NCPYNGTAIEMPQAGLDLLK-ERCGFLLQNNENKYCCDTEQVKILNKNVKLAGNFLDRCPSCMENLVRHICEFTCSPKQSEFMHVAATEKN----KTGGSYISAVDLHVSTDYINKTYKSCSQVSVPQTGQLAFDLMCGSYPASRCNPTKWFNFMGDATSPYVPFQITYI-----QHEPKSNSKEFKPLGPPTIPCNQAVSSELPACSCSDCEKSCPQGPPEPPPPEPFKIFGLDAYLVIMAAVFFVGVLVFL---MGSFLFTQGSSL----DENFQI-DGNDVTDDMAYRDDS-------------------------YFEKLGARTETFLEQFFTKWGTFFASNPWMTLVAGACLVVVLGYGVSHINITTDPVKLWASPNSKSRLEREFFDTKFEPFYRLEQIIIKAVDLPQIVHNTSNGPI-TFGPVFDRE-FLTNVLYLQEGIK--KLNANGTTLKDICFAPLSEDGNALEDSNCVVQSIWGYFQDDIERLDDEEEDGGFNVTYLDALFQCTSNPYLCLAPYGGPVDPAIALGGFLRAGDQLTGNTKYELANALILTFLVKNH-HNRTD------LHRALEWEKMFVEFMTNYTSHNKSKHMDIAFTSERSIEDELNRESQSDVLTILVSYLIMFMYIAISLGHVKEFKRVFIDSKITLGIGGVIIVLASVVSSVGLFGYIGVPATLIIVEVIPFLVLAVGVDNIFILVQTHQRDQRKPNETLEQQIGRILGRVGPSMLLTSLSESFCFFLGGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRKEENRMDICCFVKGKKSDSIAN-SEGLLYKFFKSVYVPFLMKKIVRVGVMVIFFAWLCFSIAIAPKIDIGLDQELAMPEDSFVLHYFQSLNENLNIGPPVYFVL-KGDLSYTNSSVQNLVCAGRYCNDDSVLTQIYLASRHSNQTYIARPASSWLDDYFDWSSTQSCCKFNPSNGSFCP--------------------------------------HQDTSCTNCNISKNSIQRPDEKSFDKYLPFFLKDNPD-----------------DSCAK------------------------------------AGHAAYGSAVRY-ANGKKG------LNVEASYFMGYHTILKTSADYFLALESARKISANITQMLQGRLMSNGVPIESALTVEVFPYSVFYVFYEQYLTMWSDTLQSMGISVLSIFVVTFVLMGFDVHSALVVVITITMIVVNLGGLMYYWNISLNAVSLVNLVMAVGISVEFCSHLVHSFSTSKSVSQIDRAADS 1197
BLAST of EMLSAG00000001950 vs. nr
Match: gi|1131312771|gb|JAV06745.1| (putative membrane protein patched/ptch, partial [Nyssomyia neivai]) HSP 1 Score: 874.389 bits (2258), Expect = 0.000e+0 Identity = 516/1334 (38.68%), Postives = 730/1334 (54.72%), Query Frame = 0
Query: 18 GRXIWFENCSQSPYLENNADKWLNCAYDGEAKEAPLL---KLERICPHLDPSEGV--CCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLG-SLSNGFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGVNGSEP-CSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVI------ASKILKTQSNLFMLPDGDDSI-------YDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLN-----LIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTK-----------------------------------------------ENGITLKDICHA------PLEP--ISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAYY-------------MDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTIDDSCCKYRAVDMSVCQSNGESKAKAQSALSFIDKFFENDDFFGGNSVNDFDDYDHEEEEKEESNSSKNGVLPESMFSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKS--QGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRA 1256
G+ IW+ C+ P ++ C Y+G K+ L + C HL EG CC + +D + KN ++A+ L RCP+C+ N K+ C TC QS F+ V+++ E ++ I+ V ++ ++++ Y SC V PS AL LMCG++G CS +WF Y+G N + PFQI+Y+ G+ +H + +G + V C+ G+N P CSC DCE +C P + V G+D +M I+FV+G +FL V +L+ + + D SI + + + + S++++G+ +++ + + H + + ++ GA E +L FFT WG FCA YP ++ + + + GI L +TTDP+ELWASP+SRSRVER+++DK F PFYRI QVI+ A NL ++ G + FGP F+K+ FL + E+Q++I+ I +NG + + H P P ++ G PV P LGGF+ E E P Y A+ ++++ ++NNY + S +L ALEWE++Y M+IAFTSERSI+DEL +E+ D+STI VSYIIMF YI SLG + R +++SKITLGLGGV+IVL SV +S+G+FGFI VPATLII E+IPFLVLAVG DNIFIMVQT QR+P+ TETH EH+GRI+G+V PS+LLTSV+ES CFFLG +SDMPAVRAFALYAGMALLIDFL+QVTCF+SL+SLD RQ +N +DI C RG K + N EGV+YK FK Y PF+M+ VR V+IIFFGW C S++V P I+VGLDQ+LSMP+DSFVL YF F+ +Y+S+G PVYFV+ S ++ S QN CGG C+ +S+++ I + SK PE +YIA PA SWIDDY W+ SCCK+ + S C + +G +S D D NG + FSKY F+ ++ DD V K G + A + AY++ R Q + Y+ I ++ ++ + + + ++S I + D++ + ++VFPYS+FYVFYEQYLTMW DT+ S+ +S L+I IVTF+L GFD +S+I+V+ I MI+INL G+MY WNISLNAVSLVNLVMAVGI+VEFCSH+ F+ SMEE+++ R+
Sbjct: 67 GQCIWYGVCNVDPLTQHKK----YCKYNGPPKKLDTKGQEALAKWCGHLFQDEGTSTCCDVEMIDTLNKNVELAANFLKRCPSCMTNLVKHMCDFTCSRTQSAFMN--VIST---EKGDKGEYITEVDLHITEQYMNGTYSSCSQVSVPSTGQLALDLMCGEYGASRCSAKKWFHYMGDEAGNAYVPFQINYIAQGD--NHTV-DGFTPLDPHVVPCNRGINAKTPACSCVDCEESCPKPPPVPPKPEPLNVLGLDAYALVMLIVFVLGTGLFLIGVCLFPSRPEGVVLRGEGST---SDLRSSIGRRLAGGHSSGELATDREDSPLQSKRSSGTWDNDQELRVHPATVTTFGDEDSGYFEKLGAKTENFLEMFFTKWGHFCASYPWLILFLGFCFVVAMGHGIKMLIITTDPVELWASPTSRSRVEREYYDKEFEPFYRIEQVIINAANLPKITHNTSNGPIE-FGPAFNKQ-FLLDVFEMQESIKQIGKDTGVTLEKICFAPLSSEFRGPVVTSDCVVQSLWGYFQDDMDTFESTDDDNGFEINYLDHLAKCFGNPYNPECLAPYGGPVDPAVALGGFLKEGEVLSGQPHYERANTIILTFLVNNYHNKS-------RLAPALEWEESYVAFMQDWLKGNKTNMNIAFTSERSIQDELKRESQSDVSTILVSYIIMFAYIAISLGHVEEFSRILIDSKITLGLGGVVIVLASVVSSVGLFGFIGVPATLIIVEVIPFLVLAVGVDNIFIMVQTHQREPKKPTETHAEHIGRILGKVGPSILLTSVSESCCFFLGGLSDMPAVRAFALYAGMALLIDFLLQVTCFVSLLSLDAVRQAENRFDIFCFARGKKTDAPAN-VEGVLYKFFKVLYVPFIMQRKVRIGVMIIFFGWLCASISVAPHIDVGLDQELSMPEDSFVLNYFRFLREYISIGAPVYFVL-KSGLNFSSTAHQNLICGGQYCNIDSMSTQIYIASKTPETSYIARPASSWIDDYFDWSASPSCCKFYPNNGSFCPHSS----------------------YGCDSCKIVLDPD-------------NGRPNATGFSKYLPFFLQDNPDD----VCAKAGHAAYG-----------------------------------------HAVNYAYNRRYR---QTQVGSTYLMGYHTILKTSSDYYEAMRAAR------KISHNITSTIHAKLRLQGKDEAFIEQLEVFPYSVFYVFYEQYLTMWPDTLKSMGISVLAIFIVTFLLMGFDIHSSLIVVITITMIVINLGGLMYMWNISLNAVSLVNLVMAVGIAVEFCSHLVHCFSVSMEESRVRRS 1285
BLAST of EMLSAG00000001950 vs. nr
Match: gi|1131312789|gb|JAV06754.1| (putative membrane protein patched/ptch [Nyssomyia neivai]) HSP 1 Score: 874.389 bits (2258), Expect = 0.000e+0 Identity = 516/1334 (38.68%), Postives = 730/1334 (54.72%), Query Frame = 0
Query: 18 GRXIWFENCSQSPYLENNADKWLNCAYDGEAKEAPLL---KLERICPHLDPSEGV--CCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLG-SLSNGFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGVNGSEP-CSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVI------ASKILKTQSNLFMLPDGDDSI-------YDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLN-----LIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTK-----------------------------------------------ENGITLKDICHA------PLEP--ISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAYY-------------MDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTIDDSCCKYRAVDMSVCQSNGESKAKAQSALSFIDKFFENDDFFGGNSVNDFDDYDHEEEEKEESNSSKNGVLPESMFSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKS--QGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRA 1256
G+ IW+ C+ P ++ C Y+G K+ L + C HL EG CC + +D + KN ++A+ L RCP+C+ N K+ C TC QS F+ V+++ E ++ I+ V ++ ++++ Y SC V PS AL LMCG++G CS +WF Y+G N + PFQI+Y+ G+ +H + +G + V C+ G+N P CSC DCE +C P + V G+D +M I+FV+G +FL V +L+ + + D SI + + + + S++++G+ +++ + + H + + ++ GA E +L FFT WG FCA YP ++ + + + GI L +TTDP+ELWASP+SRSRVER+++DK F PFYRI QVI+ A NL ++ G + FGP F+K+ FL + E+Q++I+ I +NG + + H P P ++ G PV P LGGF+ E E P Y A+ ++++ ++NNY + S +L ALEWE++Y M+IAFTSERSI+DEL +E+ D+STI VSYIIMF YI SLG + R +++SKITLGLGGV+IVL SV +S+G+FGFI VPATLII E+IPFLVLAVG DNIFIMVQT QR+P+ TETH EH+GRI+G+V PS+LLTSV+ES CFFLG +SDMPAVRAFALYAGMALLIDFL+QVTCF+SL+SLD RQ +N +DI C RG K + N EGV+YK FK Y PF+M+ VR V+IIFFGW C S++V P I+VGLDQ+LSMP+DSFVL YF F+ +Y+S+G PVYFV+ S ++ S QN CGG C+ +S+++ I + SK PE +YIA PA SWIDDY W+ SCCK+ + S C + +G +S D D NG + FSKY F+ ++ DD V K G + A + AY++ R Q + Y+ I ++ ++ + + + ++S I + D++ + ++VFPYS+FYVFYEQYLTMW DT+ S+ +S L+I IVTF+L GFD +S+I+V+ I MI+INL G+MY WNISLNAVSLVNLVMAVGI+VEFCSH+ F+ SMEE+++ R+
Sbjct: 36 GQCIWYGVCNVDPLTQHKK----YCKYNGPPKKLDTKGQEALAKWCGHLFQDEGTSTCCDVEMIDTLNKNVELAANFLKRCPSCMTNLVKHMCDFTCSRTQSAFMN--VIST---EKGDKGEYITEVDLHITEQYMNGTYSSCSQVSVPSTGQLALDLMCGEYGASRCSAKKWFHYMGDEAGNAYVPFQINYIAQGD--NHTV-DGFTPLDPHVVPCNRGINAKTPACSCVDCEESCPKPPPVPPKPEPLNVLGLDAYALVMLIVFVLGTGLFLIGVCLFPSRPEGVVLRGEGST---SDLRSSIGRRLAGGHSSGELATDREDSPLQSKRSSGTWDNDQELRVHPATVTTFGDEDSGYFEKLGAKTENFLEMFFTKWGHFCASYPWLILFLGFCFVVAMGHGIKMLIITTDPVELWASPTSRSRVEREYYDKEFEPFYRIEQVIINAANLPKITHNTSNGPIE-FGPAFNKQ-FLLDVFEMQESIKQIGKDTGVTLEKICFAPLSSEFRGPVVTSDCVVQSLWGYFQDDMDTFESTDDDNGFEINYLDHLAKCFGNPYNPECLAPYGGPVDPAVALGGFLKEGEVLSGQPHYERANTIILTFLVNNYHNKS-------RLAPALEWEESYVAFMQDWLKGNKTNMNIAFTSERSIQDELKRESQSDVSTILVSYIIMFAYIAISLGHVEEFSRILIDSKITLGLGGVVIVLASVVSSVGLFGFIGVPATLIIVEVIPFLVLAVGVDNIFIMVQTHQREPKKPTETHAEHIGRILGKVGPSILLTSVSESCCFFLGGLSDMPAVRAFALYAGMALLIDFLLQVTCFVSLLSLDAVRQAENRFDIFCFARGKKTDAPAN-VEGVLYKFFKVLYVPFIMQRKVRIGVMIIFFGWLCASISVAPHIDVGLDQELSMPEDSFVLNYFRFLREYISIGAPVYFVL-KSGLNFSSTAHQNLICGGQYCNIDSMSTQIYIASKTPETSYIARPASSWIDDYFDWSASPSCCKFYPNNGSFCPHSS----------------------YGCDSCKIVLDPD-------------NGRPNATGFSKYLPFFLQDNPDD----VCAKAGHAAYG-----------------------------------------HAVNYAYNRRYR---QTQVGSTYLMGYHTILKTSSDYYEAMRAAR------KISHNITSTIHAKLRLQGKDEAFIEQLEVFPYSVFYVFYEQYLTMWPDTLKSMGISVLAIFIVTFLLMGFDIHSSLIVVITITMIVINLGGLMYMWNISLNAVSLVNLVMAVGIAVEFCSHLVHCFSVSMEESRVRRS 1254
BLAST of EMLSAG00000001950 vs. nr
Match: gi|1131312787|gb|JAV06753.1| (putative membrane protein patched/ptch, partial [Nyssomyia neivai]) HSP 1 Score: 873.618 bits (2256), Expect = 0.000e+0 Identity = 516/1334 (38.68%), Postives = 730/1334 (54.72%), Query Frame = 0
Query: 18 GRXIWFENCSQSPYLENNADKWLNCAYDGEAKEAPLL---KLERICPHLDPSEGV--CCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLG-SLSNGFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGVNGSEP-CSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVI------ASKILKTQSNLFMLPDGDDSI-------YDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLN-----LIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTK-----------------------------------------------ENGITLKDICHA------PLEP--ISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAYY-------------MDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTIDDSCCKYRAVDMSVCQSNGESKAKAQSALSFIDKFFENDDFFGGNSVNDFDDYDHEEEEKEESNSSKNGVLPESMFSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKS--QGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRA 1256
G+ IW+ C+ P ++ C Y+G K+ L + C HL EG CC + +D + KN ++A+ L RCP+C+ N K+ C TC QS F+ V+++ E ++ I+ V ++ ++++ Y SC V PS AL LMCG++G CS +WF Y+G N + PFQI+Y+ G+ +H + +G + V C+ G+N P CSC DCE +C P + V G+D +M I+FV+G +FL V +L+ + + D SI + + + + S++++G+ +++ + + H + + ++ GA E +L FFT WG FCA YP ++ + + + GI L +TTDP+ELWASP+SRSRVER+++DK F PFYRI QVI+ A NL ++ G + FGP F+K+ FL + E+Q++I+ I +NG + + H P P ++ G PV P LGGF+ E E P Y A+ ++++ ++NNY + S +L ALEWE++Y M+IAFTSERSI+DEL +E+ D+STI VSYIIMF YI SLG + R +++SKITLGLGGV+IVL SV +S+G+FGFI VPATLII E+IPFLVLAVG DNIFIMVQT QR+P+ TETH EH+GRI+G+V PS+LLTSV+ES CFFLG +SDMPAVRAFALYAGMALLIDFL+QVTCF+SL+SLD RQ +N +DI C RG K + N EGV+YK FK Y PF+M+ VR V+IIFFGW C S++V P I+VGLDQ+LSMP+DSFVL YF F+ +Y+S+G PVYFV+ S ++ S QN CGG C+ +S+++ I + SK PE +YIA PA SWIDDY W+ SCCK+ + S C + +G +S D D NG + FSKY F+ ++ DD V K G + A + AY++ R Q + Y+ I ++ ++ + + + ++S I + D++ + ++VFPYS+FYVFYEQYLTMW DT+ S+ +S L+I IVTF+L GFD +S+I+V+ I MI+INL G+MY WNISLNAVSLVNLVMAVGI+VEFCSH+ F+ SMEE+++ R+
Sbjct: 67 GQCIWYGVCNVDPLTQHKK----YCKYNGPPKKLDTKGQEALAKWCGHLFQDEGTSTCCDVEMIDTLNKNVELAANFLKRCPSCMTNLVKHMCDFTCSRTQSAFMN--VIST---EKGDKGEYITEVDLHITEQYMNGTYSSCSQVSVPSTGQLALDLMCGEYGASRCSAKKWFHYMGDEAGNAYVPFQINYIAQGD--NHTV-DGFTPLDPHVVPCNRGINAKTPACSCVDCEESCPKPPPVPPKPEPLNVLGLDAYALVMLIVFVLGTGLFLIGVCLFPSRPEGVVLRGEGST---SDLRSSIGRRLAGGHSSGELATDREDSPLQSKRSSGTWDNDQELRVHPATVTTFGDEDSGYFEKLGAKTENFLEMFFTKWGHFCASYPWLILFLGFCFVVAMGHGIKMLIITTDPVELWASPTSRSRVEREYYDKEFEPFYRIEQVIINAANLPKITHNTSNGPIE-FGPAFNKQ-FLLDVFEMQESIKQIGKDTGVTLEKICFAPLSSEFRGPVVTSDCVVQSLWGYFQDDMDTFESTDDDNGFEINYLDHLAKCFGNPYNPECLAPYGGPVDPAVALGGFLKEGEVLSGQPHYERANTIILTFLVNNYHNKS-------RLAPALEWEESYVAFMQDWLKGNKTNMNIAFTSERSIQDELKRESQSDVSTILVSYIIMFAYIAISLGHVEEFSRILIDSKITLGLGGVVIVLASVVSSVGLFGFIGVPATLIIVEVIPFLVLAVGVDNIFIMVQTHQREPKKPTETHAEHIGRILGKVGPSILLTSVSESCCFFLGGLSDMPAVRAFALYAGMALLIDFLLQVTCFVSLLSLDAVRQAENRFDIFCFARGKKTDAPAN-VEGVLYKFFKVLYVPFIMQRKVRIGVMIIFFGWLCASISVAPHIDVGLDQELSMPEDSFVLNYFRFLREYISIGAPVYFVL-KSGLNFSSTAHQNLICGGQYCNIDSMSTQIYIASKTPETSYIARPASSWIDDYFDWSASPSCCKFYPNNGSFCPHSS----------------------YGCDSCKIVLDPD-------------NGRPNATGFSKYLPFFLQDNPDD----VCAKAGHAAYG-----------------------------------------HAVNYAYNRRYR---QTQVGSTYLMGYHTILKTSSDYYEAMRAAR------KISHNITSTIHAKLRLQGKDEAFIEQLEVFPYSVFYVFYEQYLTMWPDTLKSMGISVLAIFIVTFLLMGFDIHSSLIVVITITMIVINLGGLMYMWNISLNAVSLVNLVMAVGIAVEFCSHLVHCFSVSMEESRVRRS 1285
BLAST of EMLSAG00000001950 vs. nr
Match: gi|1036676511|ref|XP_016964591.1| (PREDICTED: Niemann-Pick C1 protein isoform X2 [Drosophila biarmipes]) HSP 1 Score: 870.152 bits (2247), Expect = 0.000e+0 Identity = 517/1343 (38.50%), Postives = 729/1343 (54.28%), Query Frame = 0
Query: 1 MYGFVLFIVGALLKVACGRXIWFENCSQSPYLENNADKWLNCAYDGEAKEAP---LLKLERICPHL--DPSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQF--YNTVVESCDVGVNGSEP-CSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENGITLKDICHA-----------------------------------------------------PLEPISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAY--------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWT-IDDSCCKYRAVDMSVCQSNGESKAKAQSALSFIDKFFENDDFFGGNSVNDFDDYDHEEEEKEESNSSKNGVL-PESM-FSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNL------TDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
++ VLF + K C +W+ C+ + + + NC Y+G A E P L L C +L + + CC + Q++++ KN ++ IL RCP+C+ N ++ C TC P+QS F+ N + V +S+V +++ E++ + Y SC V P A LMCG + C+P +WF ++G ++ + PFQI YV +H P + F N C+ VN P CSC+DCE +C E T + + G+D + IMA +F+VG I+FL L TQ + F + DG+D + D N S ++ GA E +L FT WGTF A P ++I ++ L GI ++ +TTDP++LWASP+S+SR+ER++FD F PFYR+ Q+I+KA NL ++ G +FGP+F K+ FL +L+LQ++I+ I NG LKDIC A P ++ G PV P GGF+P + Y A+A++++ ++ N+ HN + LE AL+WEK + +MDIAFTSERSIEDEL +E+ D+ TI VSY+IMF+YI SLG +KR ++SKITLG+GGVIIVL SV +S+GIFG+I +PATLII E+IPFLVLAVG DNIFI+VQT QRD R E+ + +GRI+G V PSMLLTS++ES CFFLG +SDMPAVRAFALYAG+AL+IDF++Q+TCF+SL +LD R+ +N DI C ++G K + N EG++YK F Y PF+MK+ VRA+V++IFF W C S+A+ P+I++GLDQ+L+MP DSFVL YF + + L++GPPVYFV+ ++ + QN C G C+D+S+ + I L S+ +TYIA PA SWIDDY WT +SCCK++ N D HE+ + N +KN +L P++ F KY F+ ++ D DSC K AGHAAY +VR ++ N+ +S FM +HTILK+ DY+ AL AR++SS I + G L + + V+VFPYS+FYVFYEQYLTMWSDT+ S+ +S LSI +VTFIL GFD +++++V+ I MI++NL G+MY+WNISLNAVSLVNLVMAVGISVEFCSH+ +F S ++I RA S
Sbjct: 19 LFAAVLFTLIQSSKQDC---VWYGVCNTNTFGHSQ-----NCPYNGSAIEMPEEGLDLLRARCGYLLDNNEKQFCCDKNQVEILNKNVQLAGHILDRCPSCMENLVRHICQFTCSPKQSDFMHVVATEKN----KAGVEYVSSVDLHISTEYINKTYKSCSQVSVPQTGQLAFDLMCGAYPASRCNPTKWFNFMGDPTSPYVPFQITYV-----QHEPKSKSDLFVPLNVTTVPCNQAVNSKVPACSCSDCELSCPQGPPEPTPPEPFKIFGLDAYLVIMAAVFIVGVIVFLM----GSFLFTQDDNFQI-DGND-VSDELAYRENDS------------------------------YFEKLGAHTETFLETIFTKWGTFFASNPGTILIAGATLVAVLGYGISYIEITTDPVKLWASPNSKSRIEREYFDTKFSPFYRLEQIIIKAVNLPQIVHNTSNGPI-TFGPVFEKD-FLSQILDLQESIKAIDA--NGTQLKDICFAPLSDDGSEIDVSRCVVQSVWGYFSDDREKLDENDDDNGFNVTYLDSLYACISNPYLCLAPYGGPVDPAIAFGGFLPPGAQLTGSTEYQMANALILTFLVRNH-HNKTD------LEPALKWEKKFIEFMTNYTNYNKSEHMDIAFTSERSIEDELNRESQSDVLTILVSYLIMFLYIAISLGHVKEFKRVFIDSKITLGIGGVIIVLASVVSSVGIFGYIGLPATLIIVEVIPFLVLAVGVDNIFILVQTHQRDQRKPNESLEQQIGRILGRVGPSMLLTSLSESFCFFLGGLSDMPAVRAFALYAGVALIIDFILQITCFVSLFTLDTKRKEENRMDICCFIKGKKPDSIVN-NEGLLYKFFSSVYVPFLMKKVVRASVMVIFFAWLCFSIAIAPKIDIGLDQELAMPQDSFVLHYFQSLNENLNIGPPVYFVL-KGDLAYTNSSDQNLICAGQYCNDDSVLTQIYLASRHSNQTYIARPASSWIDDYFGWTAAAESCCKHKK--------------------------------------NSSDFCPHEDTSCVKCNITKNSLLRPDAADFEKYFSFFLKDNPD-----------------DSCAK------------------------------------AGHAAYGGAVRYSYSHER-------LNIESSYFMAYHTILKSSADYFLALESARKISSNITQMLQGRLMSNGVPMESALTVEVFPYSVFYVFYEQYLTMWSDTLQSMGISVLSIFVVTFILMGFDVHSALVVVITITMIVVNLGGLMYYWNISLNAVSLVNLVMAVGISVEFCSHLVHSFATSKSVSQIDRAADS 1197
BLAST of EMLSAG00000001950 vs. nr
Match: gi|1036952576|ref|XP_017005703.1| (PREDICTED: Niemann-Pick C1 protein isoform X1 [Drosophila takahashii]) HSP 1 Score: 868.226 bits (2242), Expect = 0.000e+0 Identity = 511/1341 (38.11%), Postives = 722/1341 (53.84%), Query Frame = 0
Query: 1 MYGFVLFIVGALLKVACGRXIWFENCSQSPYLENNADKWLNCAYDGEAKEAP---LLKLERICPHL--DPSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQF--YNTVVESCDVGVNGSEP-CSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTK---------------------------------------------ENGIT------LKDICHAPLEPISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAY--------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWT-IDDSCCKYRAVDMSVCQSNGESKAKAQSALSFIDKFFENDDFFGGNSVNDFDDYDHEEEEKEESNSSKNGVL--PESMFSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNL------TDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
++ VLF + K C +W+ C+ N NC Y+G AKE P L L++ C L + CC +KQ++++ N ++ + L RCP+C+ N ++ C TC P+QS F+ N + QE + +++V +++ E++ + Y SC V P A LMCG + C+P +WF ++G +N + PFQI Y+ +H P +F N C+ VN P C+C+DC+ +C E + + + G+D + IMA +F VG I+FL L TQ + F + DG+D + D N S ++ GA E +L FFT WGTF A P +I S+ + L GI ++ +TTDP++LWASP+S+SR+ER++FD F PFYR+ Q+I+KA NL + G K+FGP+F ++ FL +L+LQ++I+NI +NG L D P ++ G PV P GGF+P + Y A+A++++ ++ N+ HN + +LE AL+WEK + +MDIAFTSERSIEDEL +E+ D+ TI VSY+IMF+YI SLG +KR ++SKITLG+GGVIIVL SV +S+GIFG+ VPATLII E+IPFLVLAVG DNIFI+VQT QRD R E+ + +GRI+G V PSMLLTS++ES CFFLG +SDMPAVRAFALYAG+AL+IDFL+Q+TCF+SL +LD R+ +N DI C ++G K + + EG++YK F Y PF+MK+ VRA+V++IFF W C S+A+ P+I++GLDQ+L+MP DSFVL YF + + L++GPPVYFV+ ++ + QN C G C+D+S+ + I L S+ +TYIA PA SWIDDY WT SCCKY+ C H++ + N +KN +L E F KY F+ ++ D D+C K AGHAAY VR ++ N+ S FM +HTILK+ DY+ AL AR++S+ I + G L + + V+VFPYS+FYVFYEQYLTMWSDT+ S+ +S LSI +VTFIL GFD +++++V+ I MI++NL G+MY+WNISLNAVSLVNLVMAVGISVEFCSH+ +F S ++I RA S
Sbjct: 17 LFAAVLFTLIQSSKQDC---VWYGVCNT-----NTIGHSQNCPYNGTAKEMPEDGLELLKQRCGFLLENNENKFCCDKKQVELLNTNVKLAGNFLDRCPSCMENLVRHICQFTCSPKQSEFMH----VVNTKKNQENIDYVNSVDLHISTEYINKTYKSCSQVSVPQTGQLAFDLMCGAYSASRCNPTKWFNFMGDATNPYVPFQITYI-----QHEPKSNSNEFTPLNVTTVPCNQAVNSKVPACACSDCDLSCPQGPTEPSPPEPFKIGGLDAYLVIMAAVFFVGVIVFLM----GSFLFTQDDNFQI-DGND-VSDELAYRENDS------------------------------YFEKLGAQTETFLETFFTKWGTFFASNPGMTLIAGASLVVVLGYGISFMEITTDPVKLWASPNSKSRLEREYFDTKFSPFYRLEQIIIKAVNLPQIVHPTSNGP-KTFGPVFDRD-FLTKILDLQESIKNIDANGTQLKDICFAPLSDDGSQIDVSSCVVQSIWGYFADDPERLDDHDDDNGFNVTYLDGLYDCISNPYLCLAPYGGPVDPAIAFGGFLPPGAQLTGSTEYQLANALILTFLVKNH-HN------VTELEPALKWEKKFVEFMTNYTRDNKSEHMDIAFTSERSIEDELNRESQSDVLTILVSYLIMFLYIAISLGHVKEFKRVFIDSKITLGIGGVIIVLASVVSSVGIFGYFGVPATLIIVEVIPFLVLAVGVDNIFILVQTHQRDQRKPNESLEQQIGRILGRVGPSMLLTSLSESFCFFLGGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRKEENRMDICCFIKGKKPDSIVS-NEGLLYKFFSSVYVPFLMKKIVRASVMVIFFAWLCFSIAIAPKIDIGLDQELAMPQDSFVLHYFQSLNENLNIGPPVYFVL-KGDLAYTNSSDQNLICAGQYCNDDSVLTQIYLASRHSNQTYIARPASSWIDDYFGWTAAAGSCCKYKKDTGDFCP--------------------------------------HQDTSCLKCNITKNSLLRPDEKAFEKYLPFFLKDNPD-----------------DTCAK------------------------------------AGHAAYGGGVRYSYRHER-------LNIETSYFMAYHTILKSSADYFLALESARKISANITQMLQGRLMSNGVPMETALTVEVFPYSVFYVFYEQYLTMWSDTLQSMGISVLSIFVVTFILMGFDVHSALVVVITITMIVVNLGGLMYYWNISLNAVSLVNLVMAVGISVEFCSHLVHSFATSKSVSQIERAADS 1195
BLAST of EMLSAG00000001950 vs. nr
Match: gi|1036952594|ref|XP_017005704.1| (PREDICTED: Niemann-Pick C1 protein isoform X2 [Drosophila takahashii] >gi|1036952610|ref|XP_017005705.1| PREDICTED: Niemann-Pick C1 protein isoform X2 [Drosophila takahashii] >gi|1036952622|ref|XP_017005706.1| PREDICTED: Niemann-Pick C1 protein isoform X2 [Drosophila takahashii]) HSP 1 Score: 867.455 bits (2240), Expect = 0.000e+0 Identity = 508/1341 (37.88%), Postives = 726/1341 (54.14%), Query Frame = 0
Query: 1 MYGFVLFIVGALLKVACGRXIWFENCSQSPYLENNADKWLNCAYDGEAKEAP---LLKLERICPHL--DPSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQF--YNTVVESCDVGVNGSEP-CSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTK---------------------------------------------ENGIT------LKDICHAPLEPISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAY--------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWT-IDDSCCKYRAVDMSVCQSNGESKAKAQSALSFIDKFFENDDFFGGNSVNDFDDYDHEEEEKEESNSSKNGVL--PESMFSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNL------TDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
++ VLF + K C +W+ C+ N NC Y+G AKE P L L++ C L + CC +KQ++++ N ++ + L RCP+C+ N ++ C TC P+QS F+ N + QE + +++V +++ E++ + Y SC V P A LMCG + C+P +WF ++G +N + PFQI Y+ +H P +F N C+ VN P C+C+DC+ +C E + + + G+D + IMA +F VG I+FL + S + S++ DD+ Q +G+ D + ++ + ++ GA E +L FFT WGTF A P +I S+ + L GI ++ +TTDP++LWASP+S+SR+ER++FD F PFYR+ Q+I+KA NL + G K+FGP+F ++ FL +L+LQ++I+NI +NG L D P ++ G PV P GGF+P + Y A+A++++ ++ N+ HN + +LE AL+WEK + +MDIAFTSERSIEDEL +E+ D+ TI VSY+IMF+YI SLG +KR ++SKITLG+GGVIIVL SV +S+GIFG+ VPATLII E+IPFLVLAVG DNIFI+VQT QRD R E+ + +GRI+G V PSMLLTS++ES CFFLG +SDMPAVRAFALYAG+AL+IDFL+Q+TCF+SL +LD R+ +N DI C ++G K + + EG++YK F Y PF+MK+ VRA+V++IFF W C S+A+ P+I++GLDQ+L+MP DSFVL YF + + L++GPPVYFV+ ++ + QN C G C+D+S+ + I L S+ +TYIA PA SWIDDY WT SCCKY+ C H++ + N +KN +L E F KY F+ ++ D D+C K AGHAAY VR ++ N+ S FM +HTILK+ DY+ AL AR++S+ I + G L + + V+VFPYS+FYVFYEQYLTMWSDT+ S+ +S LSI +VTFIL GFD +++++V+ I MI++NL G+MY+WNISLNAVSLVNLVMAVGISVEFCSH+ +F S ++I RA S
Sbjct: 17 LFAAVLFTLIQSSKQDC---VWYGVCNT-----NTIGHSQNCPYNGTAKEMPEDGLELLKQRCGFLLENNENKFCCDKKQVELLNTNVKLAGNFLDRCPSCMENLVRHICQFTCSPKQSEFMH----VVNTKKNQENIDYVNSVDLHISTEYINKTYKSCSQVSVPQTGQLAFDLMCGAYSASRCNPTKWFNFMGDATNPYVPFQITYI-----QHEPKSNSNEFTPLNVTTVPCNQAVNSKVPACACSDCDLSCPQGPTEPSPPEPFKIGGLDAYLVIMAAVFFVGVIVFL---MGSFLFTQGSSM------DDNF------------------QIDGN-----DVSDELAYRENDSYFEKLGAQTETFLETFFTKWGTFFASNPGMTLIAGASLVVVLGYGISFMEITTDPVKLWASPNSKSRLEREYFDTKFSPFYRLEQIIIKAVNLPQIVHPTSNGP-KTFGPVFDRD-FLTKILDLQESIKNIDANGTQLKDICFAPLSDDGSQIDVSSCVVQSIWGYFADDPERLDDHDDDNGFNVTYLDGLYDCISNPYLCLAPYGGPVDPAIAFGGFLPPGAQLTGSTEYQLANALILTFLVKNH-HN------VTELEPALKWEKKFVEFMTNYTRDNKSEHMDIAFTSERSIEDELNRESQSDVLTILVSYLIMFLYIAISLGHVKEFKRVFIDSKITLGIGGVIIVLASVVSSVGIFGYFGVPATLIIVEVIPFLVLAVGVDNIFILVQTHQRDQRKPNESLEQQIGRILGRVGPSMLLTSLSESFCFFLGGLSDMPAVRAFALYAGVALIIDFLLQITCFVSLFTLDTKRKEENRMDICCFIKGKKPDSIVS-NEGLLYKFFSSVYVPFLMKKIVRASVMVIFFAWLCFSIAIAPKIDIGLDQELAMPQDSFVLHYFQSLNENLNIGPPVYFVL-KGDLAYTNSSDQNLICAGQYCNDDSVLTQIYLASRHSNQTYIARPASSWIDDYFGWTAAAGSCCKYKKDTGDFCP--------------------------------------HQDTSCLKCNITKNSLLRPDEKAFEKYLPFFLKDNPD-----------------DTCAK------------------------------------AGHAAYGGGVRYSYRHER-------LNIETSYFMAYHTILKSSADYFLALESARKISANITQMLQGRLMSNGVPMETALTVEVFPYSVFYVFYEQYLTMWSDTLQSMGISVLSIFVVTFILMGFDVHSALVVVITITMIVVNLGGLMYYWNISLNAVSLVNLVMAVGISVEFCSHLVHSFATSKSVSQIERAADS 1199
BLAST of EMLSAG00000001950 vs. nr
Match: gi|1000717574|ref|XP_015594568.1| (PREDICTED: Niemann-Pick C1 protein isoform X1 [Cephus cinctus]) HSP 1 Score: 867.07 bits (2239), Expect = 0.000e+0 Identity = 527/1350 (39.04%), Postives = 739/1350 (54.74%), Query Frame = 0
Query: 4 FVLFIVGALLKVAC----GRXIWFENCSQSPYLENNADKWLNCAYDGEAK----EAPLLKLERICPHL--DPSEGV--CCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNG-FTPFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGVNGSEP-CSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFL-AIVIASK---------ILKTQSNLFMLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKE---------------------------------EFLFPLLELQKNIENI--------------KTKENGITLKDICH---------APLEPISDGGIPVQPYYMLGGFIPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAY--------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTIDDSCCKYRAVDMSVCQSNGESKAKAQSALSFIDKFFENDDFFGGNSVNDFDDYDHEEEEKEESNSSK-NGVLPESMFSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNL--TDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRA 1256
F L + A +K G IW+ C P L++ NC Y+G AK E +L L ++CPHL D +GV CC +QL ++ N ++++ L RCP+CL+N +K+FC TC QS F+ +TS E + + + Y+ ++++ Y SC V PS AL LMCG+WG CS ++WFRY+G +N + PFQI+Y+ ET P+ G + + C +N P CSC DCE++C P + + G DG +M IIFV G I+FL AIV SK ++ Q L G DG + +E + Q+ SS VD V N I+R GA +++ L F +WGT CA P ++ + LS + L GI +L+VTTDP+ELWASP SRSRVERD+FD F PFYR Q+I+ A L + ++ G +FGP+F+ F P Q I++I + ENG + + H P GG P+ P +GGF+ + + +P Y EA+A++++ ++NNY HN KL+ A+EWEK + YM++AF SERSIEDEL +E+ DI TI VSYIIMF YI SLG+ T R +++SKITLGLGGV+IVL SV S+G FGF+ +PATLII E+IPFLVLAVG DN+FI+VQT QR+ R E+ EH+GR +G+V PSMLLTS +ES CFFLG +SDMPAV+AFALYAG+ALL+DF++Q+TCF+SL++LD RQ +N D+ C + GSKK+ + +G++YK+FK Y P +M++WVR V++IFFGW CTS+AV P IEVGLDQ+LSMP+DSFVLKYF F+ YLSVGPP+YFVV ++ S QN CGG C+ +S+ I SKQ +TYIA PA SW+DDY+ W++ CCKY F GN N F + +K ++K N +PE F +Y F+ ++ DD KC + G ++ + ++ +NP + G A+Y F Y+ I + ++ ++ + R+S+ I +N NL K+ V+VFPYS+FYVFYEQYLTMW DT+ S+ +S L+I +VTF+L G + +SI++++ I MI+IN+ G+MY+W+I+LNAVSLVNLVMAVGISVEFCSH+ AF+ S++ T++ RA
Sbjct: 20 FALLAILAFMKATSAANDGHCIWYGQCYVDPVLQHKK----NCVYNGTAKVLDTEGQIL-LHKLCPHLLTDSGDGVRTCCDVEQLKTLDANIKLASNFLKRCPSCLNNLQKHFCEFTCSQSQSAFIN---ITS--IEEDANTTYVDGIDVYITKKYLEGTYKSCSQVSVPSTGELALDLMCGEWGASRCSAFKWFRYMGDAANNIYVPFQINYI---ET-DAPL-NGFTPMDPTITPCSKPLNAMSPACSCLDCEASCPIPPPAPPIPKPFTIAGYDGYAVVMLIIFVCGTILFLMAIVCFSKRKQIVARGEVVGRQVGR-RLAAGLHHPGDGARIALAADQEDS-PLQSKRSSVVSVDDLPADLVDGQPNCIERLGAKMDV-LHTVFCWWGTVCATRPWLILFLGLSFVMILGHGIKYLHVTTDPVELWASPHSRSRVERDYFDSHFEPFYRTEQIIISAVGLPNIVHNTSNGPI-TFGPVFNNSFLLTVLELQESIKQLITPGSYALKDICYAPMSGPFYGPRAVSQCVIQSIWGYWQDSVDTFNETEVDENGFEVNYLDHFMECTGNAYGPRCRAQYGG-PILPDVAVGGFLTPGQTY-NHPPYEEATAIILTFLVNNY-HNK------TKLQPAMEWEKTFVEFMKNWTATKKPAYMEVAFNSERSIEDELNRESQSDILTILVSYIIMFAYIAISLGQIRTCSRLLIDSKITLGLGGVLIVLASVICSVGFFGFVGLPATLIIIEVIPFLVLAVGVDNVFILVQTHQREGRRPNESIPEHIGRTLGQVGPSMLLTSFSESCCFFLGGLSDMPAVKAFALYAGLALLVDFILQITCFVSLLALDTIRQANNRLDVCCFIHGSKKDNDEEVVDGILYKIFKVAYVPLLMQKWVRTGVMVIFFGWLCTSIAVVPHIEVGLDQELSMPEDSFVLKYFKFLNNYLSVGPPMYFVV-KDGLNYSDTETQNLICGGQYCNSDSITGQIFAASKQSNRTYIAKPAASWLDDYIDWSMSPDCCKY----------------------------------FPGN--NSFCPHTDRSCKKCNITANKYNRPIPED-FGRYVSFFLEDNPDD--------------------KC---------AKGGHASYSSGVNYW--ENPKTHVSRVG-ASY----------------FMAYHTILKSSADYYEAMRAAR----------RVSANITEMLNKNLKAAGKTGEVEVFPYSVFYVFYEQYLTMWPDTLQSIGISLLAIFVVTFLLMGLNICSSIVVLITITMIVINIGGLMYWWHITLNAVSLVNLVMAVGISVEFCSHLVHAFSVSIQPTRVERA 1245
BLAST of EMLSAG00000001950 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold609_size125094-snap-gene-0.22 (protein:Tk01016 transcript:maker-scaffold609_size125094-snap-gene-0.22-mRNA-1 annotation:"niemann-pick c1 isoform x7") HSP 1 Score: 1072.38 bits (2772), Expect = 0.000e+0 Identity = 576/1328 (43.37%), Postives = 798/1328 (60.09%), Query Frame = 0
Query: 23 FENCSQS----PYLENNADKWLNCAYDGEAKEAPLLKLERICPH----LDPSEG---VCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESCDVGVNGSEPCSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLAIVIASKILKTQSNLFMLPDGDDSIYDGTPV--TPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKEEFLFPLLELQK----------------------------NIENI-----KTKEN----------GITLKDICH-----------------APLEPISDGGIPVQPYYMLGGFIPEN-EPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAY---------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNV--DLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTIDDSCCKYRAVDMSVCQSNGESKAKAQSALSFIDKFFENDDFFGGNSVNDFDDYDHEEEEKEESNSSKNGVLPESMFSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSMEETKILRAKTS 1259
FEN S + PY ++N + + GE L KL+ CPH L P E VCC+ Q++ + NF + S+L RCP+CL NF+KNFC +TC P QS FL + + T EV ++ +TYY++ E+ ++ YDSCK V+ P+ SG A+ L+CG WG + CSP RWF Y+GS SNG++PF I +V S E +G + +N V C+ G CSC DC C P FEE + V +DG FIM +IF++G ++FLA+V +K+++T DD+ D P+ TP+G + LN+I R G L L + F WGTFCA YP+PVI+ + A+ LC+G+ WL +TTDP+ELWA+P SRSR E+++FD TFRPFYR QVI AKNL F+Y D G ++FGP+FH +EFL PLL LQ+ NI+N+ ++EN G L + H PL +S GGIPVQP+++LGGFIPE PQN +Y + AVV+SI+++N+D S + E +L KA EWEKA+ YMD+AF SERSIEDELA++T GD+ TI +SY IMF+YIT +LG+ T+++ MVESKITLG+ GV++VLLSV ASIGIFGF ++ +TLIIFEIIPFLVLAVG DNIFI+VQT QR R ET EHVGR+VGEV PSMLL+S++E+TCFFLGA++DMPAV +FAL AGMA+LIDF MQ+TCF+SL +LDM RQ + YDI+CC + SKK + +GV+Y+LF+ FYAPF++ +W+R VV++F W C+SLAV P +EVGLDQ++SMPDDSFVLKYF +++ YLSVGPP Y +D+ ++ + S P +QN+ G G +SLN+ + WS + + TY+A+ AQSW+DDY +W + +CC Y + + VCQSN + D+E ES + G+ PE C+ C +D RP P F ++++WFL+D+PG+ CP AG AAY VRL A D E F Y+V A+NFM FHTIL+T D+ EALRW+R+L+ I+ ++N +L ++ + + +F YS+FYV+YEQYLTMW D++ +L S L++ VT +L G D +++I+++VI MILIN++G+MY+WNI LN V+LVNLV+ +GISVEFC+H+ ++F+ + E I R+K +
Sbjct: 628 FENPSFAGRYLPYHDSNPARHME---PGET----LNKLQLACPHFSEDLGPPENGWDVCCAPDQIEDLVTNFVLPESVLDRCPSCLDNFRKNFCDLTCRPDQSSFLNVSGIITQTNATGTEVELVVELTYYISKEYNEKTYDSCKDVINPATSGPAMSLLCGPWGAEKCSPQRWFDYMGSTSNGYSPFDILFVISDEETL----DGFEMHNPTVVPCNESSMGKPQCSCTDCLDTCTPVVFEEP-TELFKVGKLDGVAFIMILIFILGTVLFLALVFTNKLVQTTD--------DDTSLDEEPISQTPHGPPK--------------------------LNVIDRMGVKLILTMERLFARWGTFCAYYPVPVIVFGVVAALILCSGVQWLKITTDPVELWAAPGSRSRSEKEYFDSTFRPFYRTAQVIAAAKNLPDFEYTDADGIEQTFGPVFHADEFLKPLLRLQEAIQNITTASGLKLQDVCNAPLSPQDNVCNIQNVWAYWQDSEENFDLIRFDANTGNNLTYLDHFLTCARNPALPTDGNQVNPLGCMSKGGIPVQPFFVLGGFIPEGVSGLPQNANYQGSKAVVMSIIVDNFDMYSTDHESQLRLTKAKEWEKAFIEFMKEWEKNPDNTQYMDVAFNSERSIEDELARQTQGDVKTIVISYAIMFVYITIALGQFTSFRTIMVESKITLGISGVLLVLLSVGASIGIFGFANIESTLIIFEIIPFLVLAVGVDNIFILVQTYQRSERKPYETLPEHVGRVVGEVGPSMLLSSLSEATCFFLGALTDMPAVYSFALNAGMAILIDFFMQITCFVSLTALDMYRQESHRYDIVCCAKASKKTKKAG--KGVLYRLFEQFYAPFILSKWLRPTVVVVFLAWLCSSLAVAPHLEVGLDQEISMPDDSFVLKYFEYMKDYLSVGPPFYITLDNKDLKFNFSDPAMQNRLSGSFGSLPDSLNAQVKQWSIRSDITYVASTAQSWLDDYFSWLRNSACCSYNQITLDVCQSNYQG--------------------------------DNELPWHPESRTGPGGIGPEK---------------------------------DCVDC-EPMAGVD-NRPTPFQFEKHLQWFLQDSPGDVCPPAGKAAYRDGVRL-AELGADQEGFPHYDVSANNFMVFHTILRTSTDFSEALRWSRKLTDAIDETVNKDLGEEER-LNIFAYSVFYVYYEQYLTMWEDSLETLGYSLLAVFCVTLVLLGLDIASALIVILVILMILINMIGLMYWWNIQLNGVTLVNLVVTIGISVEFCAHMVRSFSVTNESDMIKRSKAT 1838
BLAST of EMLSAG00000001950 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold22_size673200-snap-gene-4.23 (protein:Tk12689 transcript:maker-scaffold22_size673200-snap-gene-4.23-mRNA-1 annotation:"niemann-pick c1 protein isoform x3") HSP 1 Score: 733.791 bits (1893), Expect = 0.000e+0 Identity = 468/1344 (34.82%), Postives = 697/1344 (51.86%), Query Frame = 0
Query: 5 VLFIVGALLKVACG-RXIWFENCSQSPYLENNADKWLNCAYDGEAKEAPL---LKLERICPHLDPSEGVCCSEKQLDVMEKNFNISASILGRCPTCLHNFKKNFCAMTCHPQQSYFLQGQVMTSNHFETQEEVSVISNVTYYVADEFVQRVYDSCKXVVTPSVSGTALKLMCGKWGDKLCSPYRWFRYLGSLSNGFTPFQIDYVFSGETRHHPIPEGIQFYNTVVESCD-VGVNGSEPCSCADCESACEPPHFEETQVGFYIVPGVDGTIFIMAIIFVVGXIIFLA--IVIASKILKTQSNLF-MLPDGDDSIYDGTPVTPNGSEESTTSQQTNGSSNHEVDAKGHVQVMQSLNLIQRAGADLELWLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSFKYDDFLGETKSFGPIFHKE---EFLFPLLELQK------------------------NIENI---------KTKENGI---------------------TLK-DICHAPLEPISDGGIPVQPYYMLGGF-IPENEPFPQNPSYHEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAY-------------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRD-PRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGG---EGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVD----SSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDYLAWTIDDSCCKYRAVDMSVCQSNGESKAKAQSALSFIDKFFENDDFFGGNSVNDFDDYDHEEEEKEESNSSKNGVLPESMFSKYDQFYYYEDEDDNQNSVQTKKGRSKRATDSCIKCPNSDDAIDLKRPGPKAFRRYMKWFLEDNPGERCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAF-THSMEETKILRAKTS 1259
+ +++ L VA G + +W++ C P N LNC YDG K P + L+ CP+ + +E CCS Q+ M F + AS+LGRCP+CLHNFKK FC M+C P QS F++ E +S++ V +++ EF +VYDSCK VV PS SG+ L+LMCG WG LC+ R+F YLG+ +N TP +I++ E H EG + YN CD NG CSC DCE AC+ P F + +++ F + ++ I FL+ + I ++ ++ ++ M+ GD + T + + G+ Q+LN ++ + F WG CA++ ++ + ++ + GIF++ V TDP+ LW++P+SRSRVE+DFF+ F PF+R+ Q+I+K K F Y + + G +F E E L L E+Q NI++I K E+GI TL+ D +S GG+PVQP ++LGGF + ++ + + +A++++I++NN+ PN + A++WEK + M+I F SERSI+DEL + + GDI+ + +SY M +YI SLG+ + F V+ KITL L G + VLL++A++IG G++ +P TLIIF+I+PFL+LAVG DNIFI+V T Q +T+ E + V +V PS+L+++V + T F LG ISDMPAVR+F++YA MAL +F++Q+T FI + D+ RQ DI CC++ S + +G +L+ Y PF+ + VR VV++F W C S+ + P I VGL+Q+++MPDDS VL+YF ++ LSVGPPVYFVV+ S D SL Q+K CGG GC+ + L + I LWSK+P T IA PAQSWIDD+ +W KY CQ +G + QS ++ + ++ +Y EE EES C C D RP P F + FL NP E CPKAG AAY ++ L + ES V AS+F FH++L+ D+ EALRW+RRL+ + + +N Q V+VFPYSIFYVFYEQYLTMWSDT+ SL V+ +++ +V TG D +++ I+V I + L+N+ G+M I LNA+SLVNLVM VG+ VEF SH+ +AF +++ E + ++R++ +
Sbjct: 7 LFYVLARALPVALGGQCLWYDECGIDPGTGKN----LNCQYDGLPKPLPADIRVVLDEHCPYYENTELFCCSPTQVQNMVNGFGVIASLLGRCPSCLHNFKKAFCDMSCSPDQSDFMKVTKTVEVRGYDNESISLVHEVDFHLDKEFGIQVYDSCKDVVNPSTSGSVLELMCGSWG-SLCTAQRFFTYLGNPANQNTPIRINFYLESEPHH----EGGKLYNRSTIHCDEAPPNGDGACSCTDCERACQSPDFGQV---YHLSDEDSENYFDLWLLLGCLGIFFLSMGVFIGCLWMRHRTKIYPMMASGD---------------KKTKAAASCGT--------------QTLNK----------FMFDQFYRWGLMCARHAAKIMALGFALVLVASGGIFFIEVETDPVRLWSAPTSRSRVEKDFFETAFEPFFRVEQIILKPKKNDPFMYRNLFEDDIQMGAVFRPEFMLETLRLLKEVQALTTSSGVSLSDICHKPLAPDQQECNIQSIWAYWQDDPDKFLESGINPTTGHNDTYIDHFLMCSNNPTLQQDQTFMKQGCMSKGGVPVQPVFVLGGFDLSKSNASQGSQQFSNPTALIVTILVNNH----PNDTHL-----AMDWEKTFVEFMNAQLEEGSDLMEITFNSERSIQDELERSSLGDIAVVLISYSTMLVYIMVSLGKIYSKSTFFVDIKITLSLIGTLGVLLAIASAIGTLGYLGLPTTLIIFQILPFLILAVGVDNIFILVNTVQSILEEDSTKDVKEIIALAVAKVGPSILMSTVAQVTAFLLGGISDMPAVRSFSIYAAMALAWNFVLQMTIFIGALYWDLYRQCALRADIFCCLQRSPREEPLDGDFRPGSWFQRLWTELYVPFLFNQVVRKMVVVVFAAWTCASIWLIPHIRVGLEQEVAMPDDSQVLRYFNALKSDLSVGPPVYFVVNRTRPDSPFDFSLEASQDKICGGRGCNSDGLQAQIKLWSKEPRITRIATPAQSWIDDFFSWA------KY------CCQHDGLGQPCEQSDSAY-------------SQYGEYSEYGTYGEEAEESA-------------------------------------------PCTPCITKGD-----RPEPSLFGTLVPRFLAQNPDESCPKAGKAAYRHALHLSP---GEGESV---QVEASSFFAFHSVLRDSNDFTEALRWSRRLADNLTSMLNSG----DQHVRVFPYSIFYVFYEQYLTMWSDTLISLAVAVVAVFLVVLAFTGLDVFSAVAIMVTILVTLVNMGGVMVILGIDLNAISLVNLVMTVGVGVEFSSHLVQAFRSYTDEPSGLVRSRKA 1207
BLAST of EMLSAG00000001950 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold28_size608977-snap-gene-1.19 (protein:Tk05739 transcript:maker-scaffold28_size608977-snap-gene-1.19-mRNA-1 annotation:"AGAP010394-PA") HSP 1 Score: 100.523 bits (249), Expect = 1.824e-21 Identity = 126/625 (20.16%), Postives = 252/625 (40.32%), Query Frame = 0
Query: 362 WLVNFFTFWGTFCAKYPIPVIIVSLSIAIGLCTGIFWLNVTTDPIELWASPSSRSRVERDFFDKTFRPFYRITQVIVKAKNLSSF-KYDDFLGETKSFGPIFHKEEFLFPLLELQKNIENIKTKENG--ITLKDICHAPLEPISDGGIPVQPYYMLGGFIPENEPFPQNPSY------HEASAVVISIMINNYDHNSPNPEEIKKLEKALEWEKAYYMDIAFTSERSIEDELAKETYGDISTIAVSY------------------------------IIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQN----------GG---------------EGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYI-AAPAQSWIDDYLAW 921
+L F G F ++P II+ + + +G ++++ DP L++ +++ER+ + F Y K+ +S K+ + K G I + ++ L + + N+ G +D+C D I L IP+ E N +Y ++ V ++ + +H + I K KA+ AY++D++ ++ D+ ++ D+S ++ +Y I + I FS G V SK +G G++ ++ A+ G FI V + + PFL+L +G D+ F+M+ + +R T E +GR + A S+ +TS+T+ F GA++ P+VR F L+ G+++ ++ T F ++++L + N + I CC++ + + N GG G+V+ F+ + F+ K WV++ V+ +F + + ++ GL+++ + DS+ + Y+ + +YF + + L G F + + N+ + YI + QSW+ D+L +
Sbjct: 9 FLKRMFYKLGHFIGEHPGYFIIIPILLTKLCASGFYFMDYQYDPEYLFSPTHGAAKLEREVLEAHFPTNYSQ----FKSSRISRVGKFARLVIAPKDGGSIL-RSSLWNQMIYLDQIVYNVTVSFEGQNYQYQDVCARWAGYCYDNEI-----LRLADLIPQVEQGQINLTYPLYFNPYDFETVTMAAFLGGVEHGE---DHIIKDAKAMSL--AYFLDVSEDWMVTVGDDWERQLLEDVSNLSATYAPDLEIGRFVSNTPAWEMEKSRLSVTNILIINVIAMIIFSFGAALMSDN--VRSKPVIGFSGLLSAGMATIAAFGFACFIGV-EFISLNMAAPFLLLGIGIDDTFVMLSSWRRSSGHLTVP--ERMGRCYSDAAVSITVTSLTDFLSFMAGAVTPFPSVRIFCLFTGISVAFIYIWHCTFFGAILALSGYGEKKNLHSICCCIKATPSSQALNRNFLFRWFMTGGINPDDPHNPRDNRDHAGMVF--FRDVFGKFLTKTWVKSLVLCLFGVYIVIACWGVTNLKEGLEKRNTANYDSYSVSYYDMED--------LYFKKYAFTISLMFTGPNINF-----ADVRTQQKIENITRMFEDSVYIDGSVTQSWLRDFLDY 598 HSP 2 Score: 60.077 bits (144), Expect = 4.703e-9 Identity = 36/117 (30.77%), Postives = 70/117 (59.83%), Query Frame = 0
Query: 1124 RRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHI 1240
+++ E+ + N TD+ Q + VF F+++ +QYL + TI ++ + + + IV+ +L ++S+ I I I + ++G M +W +SL+ V+L+NL+M +G SV+F +HI
Sbjct: 666 QQMVMELRDICNRFSTDEMQ-IAVF--QPFFIYIDQYLDIKPQTIQCVVATAIIMIIVSLLLIP-SVVSSLWISFSIISIEVGVVGFMTWWGVSLDGVALINLIMCIGFSVDFSAHI 778
BLAST of EMLSAG00000001950 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold34_size539781-snap-gene-1.9 (protein:Tk05354 transcript:maker-scaffold34_size539781-snap-gene-1.9-mRNA-1 annotation:"hypothetical protein DAPPUDRAFT_306990") HSP 1 Score: 99.3673 bits (246), Expect = 3.783e-21 Identity = 76/295 (25.76%), Postives = 141/295 (47.80%), Query Frame = 0
Query: 558 LEKALEWEKAYYMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTC-QRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIE 851
L+ + E E+ + I RS D ++ + D +A Y +MF Y LG K +VE + + GG+I V + + + G+ + +P T I I+PFL L +G D++F++VQ P T E +G + ++ +TS+T+ F +GA++ +P ++AF + +A+ +++Q + F++L+SLD R D+ C+R + + + K+F +A + K + + V+ I G F T + T I D L +P S++ ++ E
Sbjct: 409 LDGSKESEERSGVKIYANVARSFNDITSEAIFFDAVKMAAGYFLMFFYTMLFLG-----KLNLVEHRTWIAAGGIISVGMGLGIAFGVTSALGMPYT-PIHGILPFLALGIGIDDMFVIVQCWYNLSPEEQQRTLPEKIGLTMKHAGVAITVTSLTDVFAFGVGAVTILPGLQAFCVTCAIAIAAIYILQASWFVALLSLDQRRIRDHRDGFAPCIR-YRNWIPSAWTQKEYGKMFMAGFAKILKKGFTKIVVLGITLGVFGTGIYGTYLIRQEFDPVLLLPAQSYLRQWLAVQE 696 HSP 2 Score: 61.6178 bits (148), Expect = 1.343e-9 Identity = 33/122 (27.05%), Postives = 70/122 (57.38%), Query Frame = 0
Query: 1123 ARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAF 1244
RRL +EN I G K K F +S Y +E + + +L ++ + + I+T +L + ++++ I + L++++G ++FW ++++ +S +N+V+A+G+ V++ +HIA AF
Sbjct: 828 GRRL---VENLIQG----KKFSSKAFSFSKVYAAWETDEVISFELWRNLALAMVCVFIITLVLLA-NVKICLMVLSCICLTLVDMVGFLHFWGLTIDTISCINIVLAIGLCVDYSAHIAHAF 941
BLAST of EMLSAG00000001950 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold104_size368486-snap-gene-1.6 (protein:Tk07540 transcript:maker-scaffold104_size368486-snap-gene-1.6-mRNA-1 annotation:"hypothetical protein DAPPUDRAFT_306990") HSP 1 Score: 98.5969 bits (244), Expect = 8.856e-21 Identity = 65/281 (23.13%), Postives = 139/281 (49.47%), Query Frame = 0
Query: 578 RSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATE-THVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKN----VRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKY 853
RS D + + D++ + + I+FIY+ LG+ V++++ + L G++ V +++ AS GI G + P + + IPFL++ +G D++F+++Q + + T VE G + ++ +TS+T+ F +GA + +PA+++F L+ G+ +LI F +Q T F++ +SLD R + + + S ++ + ++ + F + V+ ++ + + S+ T ++ D +P DS++ ++F KY
Sbjct: 703 RSFSDIASGNIFTDVNMVVFGFAIVFIYVLLMLGQFHC-----VKNRVFVSLAGLVSVFMALVASYGICGTLGFPFS-PLHNFIPFLIMGLGIDDMFVIMQAWTKFAEHRKDLTKVEKFGETMKRAGVAITVTSITDFIAFGIGASTLLPALKSFCLFCGVGILITFFLQATWFVAWMSLDQDRIDSGRTLLFTAQKPSSEDEVSHCLSKVDKNLLQRAFDAYGQSLSQTHTVKIVILSLTTVFLAFSIWNTTQLRQEFDPVWFLPKDSYLFQWFQLKCKY 977
BLAST of EMLSAG00000001950 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold627_size122700-snap-gene-0.37 (protein:Tk10659 transcript:maker-scaffold627_size122700-snap-gene-0.37-mRNA-1 annotation:"hypothetical protein AaeL_AAEL001299") HSP 1 Score: 95.9005 bits (237), Expect = 3.495e-20 Identity = 87/395 (22.03%), Postives = 170/395 (43.04%), Query Frame = 0
Query: 558 LEKALEWEKAY----------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIIC-------------------CVRGSKKNVRQNGGEGVVYKLFKHFYAP---FVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAP--AQSWIDDY 918
+E+ WEK + ++ +A S ++E EL + T I +V+ IM ++ + + W V SK LGL G++ +L + G+ VP I PFL+L +G D+ F+ + + +R E + +G+ + A S+ +TS+T+ FF+G I+ P+V+ F LY G+A+ ++ + F + ++L + N + + C C G +N N + + + + F P F++ ++ RA +++++ + S+ ++ GL++K DS+ L+++T + Y P + F G S+E I ++ E T P ++SW+ D+
Sbjct: 220 MERGKIWEKTFLDTIETLEFEHIKVARFSSLTLEIELEENTNSVIPFFSVNIAIMVVFCVITC-LMSDW----VRSKPYLGLLGLVSAILGSITAFGVVMLCGVPFIGINLAA-PFLMLGIGIDDTFVFLSSWRRS--NPMEPIPKRLGQCYEDSAVSITITSLTDMLSFFVGIITPFPSVKIFCLYTGVAVAFTYMYHIFFFGACLALAGIAEEQNRHALTCFKVLPKSQSLEKSKMYRLFCSGGINRNDPGNQDDMPTFDMMEFFRGPFSRFLLNQYARAMIIVVYLCYLGVSIWGVSNVKEGLERKNLARFDSYSLEFYTLEDTYFRDYP---------------YRVSVTFTGALNYSNELTRFDIEDIMQRLENTTFIDPTYSESWLRDF 591
BLAST of EMLSAG00000001950 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold171_size289870-snap-gene-1.39 (protein:Tk00433 transcript:maker-scaffold171_size289870-snap-gene-1.39-mRNA-1 annotation:"hypothetical protein DAPPUDRAFT_306990") HSP 1 Score: 91.2781 bits (225), Expect = 4.996e-19 Identity = 57/208 (27.40%), Postives = 107/208 (51.44%), Query Frame = 0
Query: 571 DIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGI---FGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQ--RDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVR 773
DI + +D A+ GD + V + I+F+Y+ LG K VE++ L L G+ + L++ + G+ FG P + +IPFL+L +G D++F+++Q R + H +G + ++ +TS+T+ F +G+ + +PA+R+F LY G+ ++ + Q T F++ ++LD+ R N N I+ C +
Sbjct: 302 DILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLG-----KFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGP----MHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYK 500
BLAST of EMLSAG00000001950 vs. Tigriopus kingsejongenis genes
Match: snap_masked-scaffold472_size162276-processed-gene-0.4 (protein:Tk12251 transcript:snap_masked-scaffold472_size162276-processed-gene-0.4-mRNA-1 annotation:"hypothetical protein DAPPUDRAFT_306990") HSP 1 Score: 92.4337 bits (228), Expect = 5.759e-19 Identity = 80/319 (25.08%), Postives = 150/319 (47.02%), Query Frame = 0
Query: 557 KLEKALEWEKAY-------YMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGI---FGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRG--------SKKNVRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLS----MPDDSFVLKYFTFIEKY 853
+L KAL K + Y+++A RS D K D+ V + I+FIY+ SLG K +VE + L G+ + L+V S G+ GF+ P + IIPFL+L +G D++F++ Q+ P + T V + ++ +TS+T+ F +GA + +PA+R+F ++ + +L+ +++Q T F++ ++ D R + + C + S+KN+ Q Y L + PFV + +++++ G + L L Q+ + +P +S++ ++F EK+
Sbjct: 339 ELLKALRAPKVHADPNIVVYLNVA----RSFNDLSEKVINTDVLLFGVGFGIVFIYVQLSLG-----KLNLVEQRPFLSAVGIGCIALTVFTSYGLCSLMGFVFSP----MHNIIPFLLLGIGIDDMFVICQSLDNLPPDPSLTVETRVALAMKHAGVAITVTSITDVAVFAIGASTVLPALRSFCVFCAVGILVVYILQATIFVAALAKDSQRIASHRNGFLICYQHKNWTPQAWSQKNLLQTA----FYHLGRCLVKPFVKVAVIVCSLLLLAGGSYGLYL---------LRQEFNPIWFIPPESYLSQWFAANEKF 631 HSP 2 Score: 71.2478 bits (173), Expect = 1.634e-12 Identity = 41/148 (27.70%), Postives = 80/148 (54.05%), Query Frame = 0
Query: 1097 NVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAF 1244
+V+ S H + + P ++ A+ N I G + + + F + Y +E + +T+ +LL+S + + + T +L G +F ++++ + M L+N+ G M+FW ++++ VS VNLV+AVG+ V++ +HIA AF
Sbjct: 737 SVMLSTIQFTHHLFEGPSEHIPAM-----------NKIKGIVKSMNFSSRAFAVANEYASWETDEIIAQETVRNLLISVVCVFVTTIVLIG-NFKACALVLLSVLMTLVNVGGFMHFWGLTIDVVSCVNLVIAVGLCVDYSAHIAHAF 872
BLAST of EMLSAG00000001950 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold67_size430214-snap-gene-3.36 (protein:Tk00792 transcript:maker-scaffold67_size430214-snap-gene-3.36-mRNA-1 annotation:"patched 1 ") HSP 1 Score: 88.1965 bits (217), Expect = 1.268e-17 Identity = 66/235 (28.09%), Postives = 121/235 (51.49%), Query Frame = 0
Query: 553 EEIKKLEKALEWEKAYYMDIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQRDPRGATETHVEHVGR--IVGEV----APSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVRGSKKNVRQ 781
+E+ +L + K Y ++ S+ ++ + K + + +A+ +M +Y T ++ W V S+ +GL GV++ LSVAA +G+ G +D+ +I+PFL L +G D +F++ T G T ++ H+ R I+G+V S+LL S+ F A+ +PA+RAF+L A + + + + + F +++SLD+ R + DI+CC G K R+
Sbjct: 328 QEVARLTQEKHLNKKYAINAYSNSQ--LDHIMEKYSEFSVVNLAIGLGLMALYSTVTM---VRWSD-EVFSQSGIGLCGVLLTALSVAAGLGLCGILDIAFNATTSQIVPFLALGLGVDAMFLLSHT-----YGETVSNRRHLQRENIIGDVLRKAGISVLLMSLCNIAAFLAAALIPIPALRAFSLQAAILVGFNSVAMMILFPAVLSLDLRRIFADKVDILCCYSGRKLRERR 551 HSP 2 Score: 57.3806 bits (137), Expect = 3.298e-8 Identity = 53/198 (26.77%), Postives = 91/198 (45.96%), Query Frame = 0
Query: 1067 RCPKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYL--TMWSDTINSLLVSFLSISIVTFILTGFDFLTSI----IIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAFTHSM--EETKILRA 1256
+ PK+ AY+Q FF YNV + M E +R R + + E S G+ FP + + F+EQYL +W+ +V+ +I V F+++ F FL ++ IIV V+A+++ L+G M I L+A+ V L+++ G+ ++F HI F ++ + +IL A
Sbjct: 820 KIPKSQAIAYAQI------------PFFLYNVGETEVMV------------ETIRQVREVCQKFE----------SLGLPNFPRGLPFTFWEQYLHLRLWT------MVALGAILGVIFLVSAF-FLMNMWLGAIIVTVVALMIAQLLGFMGIIGIKLSAIPAVILIVSAGMGLQFTIHICIGFITAIGNKNRRILMA 976
BLAST of EMLSAG00000001950 vs. Tigriopus kingsejongenis genes
Match: maker-scaffold193_size270907-snap-gene-0.15 (protein:Tk01088 transcript:maker-scaffold193_size270907-snap-gene-0.15-mRNA-1 annotation:"hypothetical protein DAPPUDRAFT_306990") HSP 1 Score: 84.3445 bits (207), Expect = 1.853e-16 Identity = 77/355 (21.69%), Postives = 153/355 (43.10%), Query Frame = 0
Query: 576 SERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGE-NTTWKRFMVESKITLGLGGVIIVLLSVAASIGIFGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQ---TCQRDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMAR---QNDNYYDIICCVRGSKKN-----VRQNGGEGVVYKLFKHFYAPFVMKEWVRAAVVIIFFGWFCTSLAVTPRIEVGLDQKLSMPDDSFVLKYFTFIEKYLSVGPPVYFVVDSSNVDLSLPGIQNKFCGGAGCSDESLNSLINLWSKQPEKTYIAAPAQSWIDDY 918
+ RS D GD+ + + Y I+F ++ LG N +R + +G+G II V +++G+F + I+PFL+L +G D++F++VQ T + + + ++ G + ++ +TS+T+ F +G + +PA+++F LYA + ++ + Q T F++ +++D R + D CC + N + Q G V+ H + K ++ V+I+ ++ +E D +P D+++ K+F ++Y G ++ NVD S+ NL + ++T I +SW D +
Sbjct: 407 ARRSFGDVAGSTILGDVGKLGIGYTIVFFFVMIMLGRFNCVEQRAFLSFAGIMGVGMGIITAYGVCSALGLF-------FGPMHGILPFLLLGIGIDDMFVIVQCFNTLTEEEK--SLPLIDKFGATMQHAGVAITITSITDVIAFGIGGSTVIPALKSFCLYASVGIIATYFYQCTFFVAWMAIDQRRIEAKRDG-----CCPCWTHSNWTPNALSQKDYLGSVFTAIGH----GLTKGPIKILVIILTLAITGVAIWGNVLLEQEFDITWFLPPDTYIAKWFVKNKEYFPFGGD-RVIIYCHNVDYI----------------HDYESIANLVDQIKQQTDIVDDVESWTDPF 726 HSP 2 Score: 68.5514 bits (166), Expect = 1.086e-11 Identity = 44/176 (25.00%), Postives = 87/176 (49.43%), Query Frame = 0
Query: 1069 PKAGHAAYSQSVRLKAHPQKDNESFFQYNVIASNFMTFHTILKTPKDYYEALRWARRLSSEIENSINGNLTDKSQGVKVFPYSIFYVFYEQYLTMWSDTINSLLVSFLSISIVTFILTGFDFLTSIIIVVVIAMILINLMGMMYFWNISLNAVSLVNLVMAVGISVEFCSHIAKAF 1244
P+ G Y + K Q E+ ++ S H + PK++ A+ + L +++ S ++FP S Y +E + + +L ++ L + I T L + +TS +++V + + LI++ G M+FWN++++ VS NL++A+G+ V++ +HIA F
Sbjct: 759 PRGGK--YREQFEFKKPLQCGQEA---SQLMLSKINFVHKVFSGPKEHIPAMNRIKELIAQVNAS-----------GRIFPMSQGYTLWETDEIISEELYRNLGLAVLCVFITTLFLIS-NVITSFLVLVCVILSLIDVGGFMHFWNLTIDTVSANNLIIAIGLCVDYSAHIAHRF 917 The following BLAST results are available for this feature:
BLAST of EMLSAG00000001950 vs. GO
Analysis Date: 2014-04-02 (Blast vs. GO) Total hits: 25
Pagesback to top
BLAST of EMLSAG00000001950 vs. C. finmarchicus
Analysis Date: 2014-05-09 (TblastN vs C. finmarchicus TSA) Total hits: 25
Pagesback to top
BLAST of EMLSAG00000001950 vs. L. salmonis peptides
Analysis Date: 2014-05-10 (Blastp vs. self) Total hits: 12
Pagesback to top
BLAST of EMLSAG00000001950 vs. SwissProt
Analysis Date: 2017-02-10 (Blastp vs. SwissProt) Total hits: 25
Pagesback to top
BLAST of EMLSAG00000001950 vs. Select Arthropod Genomes
Analysis Date: 2017-02-20 (Blastp vs. Selected Arthropods) Total hits: 25
Pagesback to top
BLAST of EMLSAG00000001950 vs. nr
Analysis Date: 2017-02-20 (Blastp vs. NR (2/2017)) Total hits: 25
Pagesback to top
BLAST of EMLSAG00000001950 vs. Tigriopus kingsejongenis genes
Analysis Date: 2018-04-18 (Blastp vs. Tigriopus kingsejongensis proteins) Total hits: 13
Pagesback to topAlignments
The following features are aligned
Analyses
This gene is derived from or has results from the following analyses
Properties
Cross References
External references for this gene
Relationships
The following mRNA feature(s) are a part of this gene:
Sequences
The following sequences are available for this feature:
gene from alignment at LSalAtl2s1345:18618..29195+ Legend: mRNA Hold the cursor over a type above to highlight its positions in the sequence below.>EMLSAG00000001950-684716 ID=EMLSAG00000001950-684716|Name=EMLSAG00000001950|organism=Lepeophtheirus salmonis|type=gene|length=10578bp|location=Sequence derived from alignment at LSalAtl2s1345:18618..29195+ (Lepeophtheirus salmonis)back to top Add to Basket
|