Query:    8 SSVIVGGFERFFYWYGKLISRSPWLFLIGCLVGAGLCG--IGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQSWDDVCKRVPVIDLPGLGKQVQGPGNLRQSPCDDPSANDYDPSICLDS-------------------------------EIYCQVLDQSLSEACLETSILELFG----YEA--ETYDNLDEESILKKVNEDTPTSVVFKRPIDIGQLLSLTRDADGK-IIGARAASLSWLGQVDLEHISDGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYK-HKIEPAEKESEADYEYLS----QKVFR 523
            ++ IV G E +F W+G+ I + P +F+I CL  A L     G    R+E    KLW    +    N+E+L   FP D R+ NV++ A NVL PA +  MF++ + +S +    G +    C ++PV+  P     + G    R+   DD   +DY+ +   DS                               E YC ++D S+ E C E+S+LEL+G    YE+  +  ++L    IL  +N    + +   +      L  +TRD   K I+GA+A  + W  ++++       S   G GV VD  T+EFE ++ DI        +  G  I  ++++ + DIA  TI+GD  ++ +G++IVF YV++MLGKF+ V  R +L++ G+ S+   I+ + G+CSA G F+ PMH+++PFL+LGIGIDDMF+I+QC++ L P+E      ++  G TM+HAGVAITVTS+TD + F +G ++ LPALRSFC++  VGI A+Y+FQ TFFVA +  D +R++  RNG   C +  K++   +E   D E  S     K+FR
Sbjct:   49 TNCIVRGLESYFQWHGRFIGKHP-VFVI-CLCFAFLLASFAGFPYYRKEERRIKLWSSDKTPSRLNHEFLHEYFPSDFRFANVIVEADNVLDPAAIXAMFQMRKKISEIKTNYGDTLRTKCAKMPVVKTPNFLSFIFGKRRKRRV-ADDFFTSDYESNFFSDSFEHEMEEEEDNSGFDKDDISYPERLSVEAYPEPYCNIVD-SMEETCFESSVLELWGDNGEYESTEKRLESLSLIDILDTINNKNRSGIFLIKKNFTHMLGGITRDPITKEIVGAKATRMFWFLKMNIAEAR--KSPVEGQGVIVDKKTMEFEKEMLDIL--LNDTGLPEGLKISPHVSRSFFDIAGPTILGDVKILGIGYSIVFFYVLLMLGKFDWVGXRXYLAIAGIISVVFGIVFSIGICSAMGFFWSPMHSILPFLLLGIGIDDMFIIIQCWNTLNPYEKASSSVDKF-GYTMRHAGVAITVTSLTDIVAFGIGGTSXLPALRSFCIFSAVGIAAIYYFQVTFFVAWMVFDEKRISSGRNGCCPCIEVKKVKKNTEEIMEDMEVESLSIMSKIFR 600          

Query:   59 KLWVPSGSDFVANNEWLEANFPPDTRYN--NVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQSWDDVCKRVPVIDL-PGLGKQVQGPGNLRQSPCDD-------------PSANDYDPSI------------------CLDSEIYCQVLDQSLSEACLETSILELFGYEAETYDNLDEESILKKVNEDTPTSVV-FKRPIDIGQLLSLTRDADGKIIGARAASLSWLGQVDLEHISDGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPH-------EVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSST 450
            KLW+P  S+F++N +W+E NFP + R    ++L  + N+LTP  L  + +IH+ V  ++      W D+C +VPV ++     K +    N      DD              +  DYD +                    L  ++YC  + ++L++ C E S+LE++ ++      L ++ I++ +N    + V  +K   D   + S+ R+  G ++ A   +  W  QV+LE++S+       T   V+  +LE+E K  DIF +   A  EN +   I+ A+ ++DI  ++I  D   +  GF I+ +Y +IMLG+ NCVE R F ++ GL SI L ++V+ G+ SA GL Y P+  ++PFL LGIGIDDMF+I+QC+ N+          +   K  E M+  TMK AGV IT+TS+TD   F +G  T
Sbjct:   29 KLWIPQNSEFISNKKWIEENFPTNYRVQIISLLSLSGNILTPEALLLLLDIHEKVEQISAGHNTRWKDLCFKVPVANVFLERNKVLTNDKNTTFDRVDDLFISDDNVVPQNEKTEIDYDDAFLEYENESKNGSRYEKLLKILSPKVYCDFV-ETLNDRCFERSLLEIWKFDRRRIKRLTKDRIVQAINRIQNSPVYGYKTNYD-NYMGSIIRNETGHVVSASTLNSVWFTQVNLENVSEVI---GLTDEFVNKESLEWELKFVDIFLN---ASTENISAFGIS-ARSFNDITKKSIFFDGIRLTGGFFIMCIYTVIMLGRLNCVEVRFFATIAGLFSILLGMVVSLGIISAMGLKYSPVFAMLPFLYLGIGIDDMFIIVQCWYNILEQNKKECSTDQSIKTLEEMMAETMKDAGVTITITSLTDIFAFGIGGIT 453          

Query:   14 GFERFFYWYGKLISRSPWLFLIGCLVGAGLCG-IGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPD-----TRYNNVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQSWDDVC--KRVPVIDLPGLGKQVQGPGNLRQSPCDDPSANDYDPSICLDSEIYCQVLDQSLSEACLETSILELF-----GYEAETYDNLDEESILKKVNEDTPTSVVFKRPID--IGQLLSLTRDADGKIIGARAASLSWLGQVDLEHISDGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIG---DAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERM---IGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFC 498
            G    FY YG ++++  ++F IG  +G  +   +G ++   E++  K+W+P  S +V N + ++ +   D     T    ++ +  N+L    L  ++++H S+  +     +++ D+C  +RV V                   P   P            SEI C+ L  +    C   SI E++       EA     L +E IL  +++D   S +F+RP    IG   S   + +G + GA+A  LS+         S  ++S+   G+P+      +E  V +    F  +  +  +++ + +        AE   G   D  +   G+ IVFVY++  LG+ N +E + +L++VG+A +G+    + G+     ++  PM++++PF++LGIGIDDMFVI+Q   N++ ++ D +   +M   IG  MK AG AITVTS+TD L F +G  + LPALR+FCLY   GI  VYF+  TFF+    +D RR+  +R+  L C
Sbjct:   19 GINWIFYQYGMIVAKYSYVF-IGLSLGIFIASTLGFIDYVTESDPTKIWLPQDSYYVQNTKKIK-DLNSDAVNAATVIQVIVESEVNILRAKELNAVYKLHSSIINLKAPSNETFKDLCFKERVTV-------------------PISTPP-----------SEI-CRALANA-EWLCSAKSIFEIWTSDESSKEASIIAQLTDEDILDALSQDLAISKLFRRPFRPIIG---SKMFNDNGTLKGAKALLLSY---------SIKTNSSDKNGIPI------WEKSVKE--HVFNYSFGDESSNLSVTLFSS-SIFRAEFQNGMENDVQLFIFGYLIVFVYIIFNLGEMNTLEHKFYLAVVGIACVGMGYASSVGIFQLLSVYATPMNSILPFMLLGIGIDDMFVIVQASKNVKQND-DEEGENKMDSYIGNIMKSAGXAITVTSLTDILAFGIGGFSQLPALRNFCLYSSAGIFFVYFYIMTFFLGWFVIDARRVESHRDACLPC 468          

Query:  293 RPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYK-HKIEPAEKESEADY--EYLSQKVFRIVGQII 529
            R  + E+    LIN    + D    +I G  ++  VGF ++ +Y +++   F+ V  R  L L+G   IG+ I  ++GL    G+ Y  +H +IPFL+LGIG+DD+F+I++  DNL   E +    ER I L ++H+GV+ITVTS+TD + F++ S+TS+P LR+FCL   +GI  +YFF  TFF+A   LD RR+ + +  + F  + H + P +     +   +Y  + +F I  Q+I
Sbjct:   15 RDWVAEDWEKNLIN----FQDEIVTSIDGGMYVFGVGFLLILIYSLLVTSDFHPVNQRVMLLLLGFMVIGMAIGSSFGLGFHIGIIYADLHPIIPFLLLGIGVDDLFIIIKSTDNLSQKEKELPLKER-IALVVQHSGVSITVTSLTDLVAFLISSTTSIPLLRAFCLSVALGISFLYFFVVTFFIAWYTLDERRIEEGKAFLWFTKRVHSVPPKKSTWTHNLYKKYYVEYLFAIPSQLI 249          

Query:  241 IIGARAASLSWLGQVDLEHISDGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPAL---MENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYK 500
            IIG +A +LS+   V  E                D L L +E K  D  +   P     +E G  + ++    ++  A++  +     + V   +VF  V  ++   +  +++  +   GL S  +  +  +G     G+ +  ++   PFL+LGIG+DD FVI+  +   R    +    ERM G     A V+ITVTS+TDF  FM G  T  P +R FCLY G+ +  +YF+  T F A LA+  R    N +G +FC K
Sbjct:  206 IIGVKAVALSYFLDVSEEW--------------RDNLGLRWEKKFLDALREIGPYFAPDLEIG--MFVSNTPAWEMEASKNSVTSTLCINVVIMVVFSLVSCLMS--DATKSKPLVGFAGLFSATIATIAGFGFACYVGVEFISLNFAAPFLLLGIGVDDTFVILSSW---RRSSSNLSIPERM-GRCYSEAAVSITVTSLTDFFSFMAGVVTPFPCVRIFCLYTGISVAFIYFWHLTLFGAILAVSGRAEKNNLHG-MFCIK 445          

Query:  302 DILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLG-----KFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGP----MHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYK 500
            DI     +  +D  A+   GD   + V + I+F+Y+   LG     K   VE++  L L G+  + L++  + G+   FG    P    +  +IPFL+L +G D++F+++Q     R      + H   +G  +     ++ +TS+T+   F +G+ + +PA+R+F LY G+ ++  +  Q T F++ ++LD+ R N N   I+ C +
Sbjct:  571 DIAFTSERSIEDELAKETYGDISTIAVSYIIMFIYITFSLGENTTWKRFMVESKITLGLGGVIIVLLSVAASIGI---FGFIDVPATLIIFEIIPFLVLAVGXDNIFIMVQTCQ--RDPRGATETHVEHVGRIVGEVAPSMLLTSVTESTCFFLGAISDMPAVRAFALYAGMALLIDFLMQVTCFISLISLDMARQNDNYYDIICCVR 773          

Query:  324 FMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGI 495
            F + +G  I F  +  M+   + V+++  L L G+ S  +  L ++G     G+ +  ++   PFLMLGIGIDD FV++  +     HE         +  T + A ++IT+TSITD L F +G  T  P++R FCLY G  +   Y +  TFF   +A+       NR+ +
Sbjct:  277 FALNIGIMIAFCIITCMMT--DWVKSKPLLGLFGVISAIMAXLFSFGFIIYCGVPFIGINLAAPFLMLGIGIDDTFVMLGSWRRTSVHETV----PARLAQTYRDAAISITITSITDMLSFWIGIITPFPSVRIFCLYTGACVAFTYLWHITFFGGCMAIAGYAEKSNRHSL 442          

Query:  312 DDIAAETIIGDAFMMPVGFTIVFVYVMIMLG-----KFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGP----MHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQN 491
            D+I+ ET  GD   + + + I+FVY+ + LG     K   +E++  L++ G+  + +++  + G+   FG    P    +  +IPFL+L  G D++F+++Q      P   +   H+  IG  +     ++ +TS T+   F +G+ + +PA+R+F LY G+ ++  +F Q T F++ +ALD+ R  +N
Sbjct:  433 DEISKETT-GDINTITISYLIMFVYITLSLGDNTSCKRFLIESKITLAIGGVLIVIISVGASVGI---FGFIDXPATLIIFEIIPFLVLAXGXDNIFMLVQRAQRYGPESTE--THQEYIGRIVGDVVPSMLLTSFTESTCFFLGAISGMPAVRAFALYAGMALLIDFFMQITCFISLMALDIARQREN 615          

Query:  321 GDAFMMPVGFTIVFVYVMIMLGKFNCVETRAF---LSLVGLASIGLTILVTYGLCSAFGLFYGPM-HNVIPFLMLGIGIDDMFV-IMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCY--KHKIEPAEKESEADYEYLSQKVF-RIVGQIITKPL 533
            GD  ++ + + ++FVYV   L  F     + F   L++ G+  +  +IL T GL    G+    +   ++PFL+L +GID++FV ++     L   E    + + +IG+T++    A+ ++++T    F +G+ + +PA+ +F LY G  ++  +  Q T F+A L+LDL+R+   +  +  C   K +I+    +S  +Y+      F + V  ++ K L
Sbjct:  403 GDVLVVIISYFLMFVYVSFALTDFR--NKKYFGITLAIAGIFMVLGSILSTTGLFGFIGVKATMIIFEIVPFLVLAVGIDNIFVLVLTARRKLLSLEGREMEVDSLIGITLEEIAPAMLISTLTQTCAFYLGTLSKMPAVVTFALYAGTSLLINFLAQITGFIAILSLDLKRIKSKKLDLFCCLSDKGEIDVDNPKSRFNYQKTISTFFEKYVSPVLMKKL 621          

Query:    1 MKFLDKVSSVIVGGFERFFYWYGKLISRSPWLFLIGCLVGAGLC---GIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPNVLT 97
            +KFLDK+S++     E  FY  G  ++  PW  +   LV + +C     GL+   + T+   LW P  ++ + N  W+E N+P D+R   ++L APNVLT
Sbjct:    2 VKFLDKLSTLFTRTLENIFYRLGFTVATYPWWTI---LVSSIICLSTMTGLIWFHQTTDYEVLWAPDNTNALQNKLWIEKNYPKDSRLEYIILEAPNVLT 98          

Query:   14 GFERFFYWYGKLISRSPWLFLIGCLVGAGLCGIGLMEL-REETNAFKLWVPSGSDFVANNEWLEANFP-------------PDTRYNNVLLT--APNVLTPAILKQMFEIHQSVSTVNLTDGQS----WDDVCKRVPVIDLPGLGKQVQGPGNLRQSPCDDPSANDYDPSICLDSEIYCQVLDQSLSEACLETSILELFGYEAETYDNLDEESILKKVNEDTPTSVVFKRPIDIGQLLSLTRDADGKIIGARAASLSWLGQVDLEHISDGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILI--NIAKGYD-DIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRR 487
            GF+RF    G  +  +PWLFL+G  +     G GL+ L +E+ N  + + P GS   A   +++ +F               +T + ++L+   A ++L P I K++ ++ Q+V  + +         + +VC +   + +P        P  L                                           LF ++  +  NL +   L     +TPT +++      G +L        +++ +RA  L  L  +  E   D   S A            +     D F   + +L     +++   ++++  + +  ++T+I    +  + + ++ ++ ++   + +C+  +  +++ G+ S+ ++++  +GL    G+ +  +    PFL+LG+G+DDMF+++  +      E      ER+   +     V+IT+T+IT+ L F  G ++S  +++ FC+Y G  ++  YF+  T F A +ALD +R
Sbjct:   83 GFQRF----GATVGANPWLFLLGPALLTASLGTGLIFLPKEKENLEEQYTPIGSPAKAERRFVQGHFSTNDTYRFSASRTSSETNFASILVVSLANSLLEPEIFKEVSKLDQAVQALKVVQENGTQILYQEVCAKYKTLCVP--------PNPL-------------------------------------------LFSWQHNSSLNLSD---LTFPIHNTPTQLIYLAGFFGGNVLGQMTGKSQRLVESRAMRL--LYYLKTEDPEDSERSQA------------WLTHFLDHFNDMKSSLTLEEIEVVYFSSLSRQLEFEATSKTVIP---LFHLAYILIILFAVVSCSRLDCIRNKMCVAVFGVFSVAMSVVSGFGLMLHLGVPFVIIVANSPFLILGVGVDDMFIMISAWQKTSLSE---SIRERLSN-SYSKVAVSITITTITNVLAFYTGITSSFRSVQYFCIYTGTTLLFCYFYSITCFGAVMALDGKR 500          

Query:   15 FERFFYWYGKLISRSPWLFLIGCLVGAGLCGIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLL------TAPNVLTPAILKQMFEIHQSVSTVNLT-DGQSWD--DVC------------------KRVPVIDLPGL-----GKQVQGPGNLRQSPCDDPSANDYDPSICLDS-------EIYCQVLDQS------LSEACLETSILELFGYEAETYDNLDEESILKKVNEDTPT-SVVFKRPIDIGQLLSLTRDADGKIIGARAASLSWL---GQVDLEHI-SDGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGAD--------ILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGL-FYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYK 500
            F+   +  G  I R     L   L+  G   +GL     ETN  +LWV  GS       + +     +  Y + +L         N+LTP  L    +   + S V ++  G+SWD   +C                  K  P + L  L     G ++QG G+       D    + DP   L+        E + ++LD++      +   CL    L      A  + +    ++  +++      S  F    +   L  + RD  G+++ A A   ++L    +   EH   D  + + G      +  L+   + F   Q  + AL EN +          L +I   + +++A  ++G       G+ ++  Y  + + +++C +++  + L G+  + L +    GLC+  G+ F      V+PFL LGIG+DD+F++   F    P        ERM G  ++  G ++ +TSI +   F++ +   +PALR+F L   + +   +      F A L+LDLRR +  R  +L C+ 
Sbjct:   40 FQGLLFSLGCGIQRHCGKVLFLGLLAFGALALGLRMAIIETNLEQLWVEVGSRVSQELHYTKEKLGEEAAYTSQMLIQTARQEGENILTPEALGLHLQAALTASKVQVSLYGKSWDLNKICYKSGVPLIENGMIERMIEKLFPCVILTPLDCFWEGAKLQG-GSAYLPGRPDIQWTNLDPEQLLEELGPFASLEGFRELLDKAQVGQAYVGRPCLHPDDLHC-PPSAPNHHSRQAPNVAHELSGGCHGFSHKFMHWQEELLLGGMARDPQGELLRAEALQSTFLLMSPRQLYEHFRGDYQTHDIGWSEEQASTVLQAWQRRF--VQLAQEALPENASQQIHAFSSTTLDDILHAFSEVSAARVVG-------GYLLMLAYACVTMLRWDCAQSQGSVGLAGVLLVALAVASGLGLCALLGITFNAATTQVLPFLALGIGVDDVFLLAHAFTEALP---GTPLQERM-GECLQRTGTSVVLTSINNMAAFLMAALVPIPALRAFSLQAAIVVGCTFVAVMLVFPAILSLDLRRRHCQRLDVLCCFS 569          

Query:  304 LINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGL-FYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYK 500
            L +I + + +++   ++G       G+ ++  Y  + + +++C +++  + L G+  + L +    GLC+  G+ F      V+PFL LGIG+DD+F++   F    P   D    ERM G  ++  G ++ +TS+ + + F + +   +PALR+F L   + +   +      F A L+LDLRR ++ R  +L C+ 
Sbjct:  383 LDDILRAFSEVSTTRVVG-------GYLLMLAYACVTMLRWDCAQSQGAVGLAGVLLVALAVASGLGLCALLGITFNAATTQVLPFLALGIGVDDIFLLAHAFTKAPP---DTPLPERM-GECLRSTGTSVALTSVNNMVAFFMAALVPIPALRAFSLQAAIVVGCNFAAVMLVFPAILSLDLRRRHRQRLDVLCCFS 569          

Query:  281 FEDKVFDIFQSFRPALMENGAD---ILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFN-----CVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYG-PMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYKHKIEPAEKESE 511
            +E+      +SF+     N +D   +  +  +  +D    T I D  +  V + IVF+Y+ + LG ++      VE++A L L G+  +   +L   G  S  G+     +  V+PFL+L +G D++F+ +  +  L    +  +  E  IG T+     ++ + S+++ + F +G+ T +PA+R+F L  G+ II  +  Q T FVA L+LD +R   +R  +L C+  +  P  KE E
Sbjct:  592 WEEAFLKEMESFQ----RNTSDKFQVAFSAERSLEDEINRTTIQDLPVFAVSYIIVFLYISLALGSYSRCSRVAVESKATLGLGGVIVVLGAVLAAMGFYSYLGVPSSLVIIQVVPFLVLAVGADNIFIFVLEYQRL--PRMPGEQREAHIGRTLGSVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAIILDFLLQMTAFVALLSLDSKRQEASRPDVLCCFSTRKLPPPKEKE 825          

Query:   15 FERFFYW----YGKLISRSPWLFLIGCLVGAGLCGIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPN-----------VLT--PAI----LKQMFEIHQSVSTVNLTDGQSWDDVCKRVPVI---DLPGLGK-QVQGPGNLRQSPCDDPSANDYDPSICLDSEIYC-QVLDQSLSEACLETSILE-LFGYEAETYDNLDEESILKKVNEDTPTSVVFKRPID----IGQLLSLTRDADGKIIGARAASLSWLGQVDLEHISDGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFL--SLVGLASIGLTILVTYGLCSAFGLFYGPMH--------NVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYK 500
            F  FFY     +G   ++ P + L  C         G+  +   T+  +LW    S      ++ + +F P  R N + + A N           VL   PA     LK++FE+  S+  + + D +  D +C   PV+   + P + +  +Q      Q   D    N Y     +DS  Y    L+Q   E CL   ++E  FG                           F  PI+    +G +  +    D   + A    L++LG+    + +D S              LE   K   +F  F      +  DI     +   D   E   G+   + + + ++FVYV I LG       R FL  S + LA  G+ I++   +CS  G F+G +          VIPFL+L +G+D++F+++  +  L   +  FK     IG  +   G +I  T+ ++   F +G  + +PA+++F +Y  + I+  +  Q T FVA +A+D +R    R  +L C K
Sbjct:  306 FGEFFYHGFRIWGTFCAKHPVIVLALCSWAIAGLSFGIRYMTITTDPVELWAGEESQTRIEKDYFDQHFGPFYRTNQMFVKAVNQTYFTHETSNGVLNFGPAFEYNFLKEVFELQDSIMKLGMADNEGLDKIC-YAPVLMAGETPTVDRCAIQSVYGYFQHDMDR-FENSY-----VDSNNYTINYLNQL--EDCLRVPMMEDCFG--------------------------TFGGPIEPGIAVGGMPKVAVGEDPDYMLATGLVLTFLGR----NYNDESK-------------LEPNMKWEKLFVDFLRDYKSDRLDIAYMAERSIQDAIVELSEGEVSTVVISYVVMFVYVAIALGHIR--SCRGFLRESRIMLAIGGIVIVLASVVCS-LG-FWGYLDVTTTMLAIEVIPFLVLAVGVDNIFIMVHTYQRLDHSK--FKTTHEAIGEAIGQVGPSILQTAGSEMACFAIGCISDMPAVKTFAMYAAIAILLDFLLQITAFVALMAIDEKRYLDGRLDMLCCVK 774          

Query:    5 DKVSSVIVGGFERFFYWYGKLISRSPWLFLIGCLVGAGLCGIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQSWDDVCKRVPVIDLPGLGKQVQGPGNLRQSPCDDPSANDYDPSICLDSEIYCQVLDQSLSEACLETSILELFGYEAETYDNLDEESILKKVNEDTPTSVVFKRPIDIGQLLSLTRDADGKIIGARAASLSWLGQVDLEHISDGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDD------IAAETII---------GDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCS--AFGLFYGPMH----NVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYK 500
            D VS+   G   R F  +G    R+P   +   LV    C  GL+ +R  TN   LW    S      E+ + +F P  R   +++ A     P   K +++ + S + V               P +D+  L + +       Q   ++ +A+ YD       +I C       +  C   S+L  F       D+   +      +  T      + P  +    SL  D      G        LG  D     D + +NA   V    +T    +   D  +  R    E      IN  K Y +        AE  I          D F + + + I+F+Y+ + LG           S V L   G+ I+++   CS   F     P+      VIPFL+L +G+D++F+++Q +   R   +  +  ++ +G  +     ++ ++S ++ + F +G+ + +PA+ +F L+ G+ +   +  Q T FV+ L LD++R  +NR  I  C +
Sbjct:  325 DPVSAAFEGCLRRLFTRWGSFCVRNPGCVIFFSLVFITACSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIRA-----PLTDKHIYQPYPSGADVPFG------------PPLDIQILHQVLD-----LQIAIENITAS-YDNETVTLQDI-CLAPLSPYNTNCTILSVLNYFQNSHSVLDHKKGDDFFVYADYHTHFLYCVRAPASLNDT-SLLHDPCLGTFGGPVFPWLVLGGYD-----DQNYNNATALV----ITFPVNNYYNDTEKLQRAQAWEKE---FINFVKNYKNPNLTISFTAERSIEDELNRESDSDVFTVVISYAIMFLYISLALGHMKSCRRLLVDSKVSLGIAGILIVLSSVACSLGVFSYIGLPLTLIVIEVIPFLVLAVGVDNIFILVQAYQ--RDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLGALSVMPAVHTFSLFAGLAVFIDFLLQITCFVSLLGLDIKRQEKNRLDIFCCVR 802          

Query:  280 EFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFM---MPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYK----HKIEPAEKESEADYEYL-SQKVFRIVGQIITK 531
            E  ++  D+F S  P   E  + I  + +K    +A E       +   MP    ++ V+ M      N V+++ F+    + +  +  + +  L       + P+  ++PFL++ IG D+MF++++ +   R  +    + +R I   +  +  ++ +TS+TD L F +GS +   A+R FC YC + I+ ++ FQ TFF A ++L  RR    ++ +  CY+     + +  EK+S  D+  + ++ +F+I+  + ++
Sbjct:  222 ESTERWIDLFLSAIPRYKETNSTIFWSSSKS---LAKEMERNGELLIPWMPWTSLVLVVFCMFACSSLNIVKSQPFIGFFAMFNATMATIASTSLLLYLQYPFLPLVFIMPFLVVSIGTDNMFLMLKSW---RMTKKSSNEEQRYIH-ALTESAASLFLTSLTDGLSFAIGSISDFHAVRVFCTYCAMAILFMFLFQVTFFNAVMSLCCRREVSGKHPVFCCYEITPPEETQVLEKQSNFDFSSIVAKHLFKILNPLPSR 474          

Query:  304 LINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGL-FYGPMHNVIPFLMLGIGIDDMFVIMQCFDNL-RPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCY 499
            L +I K + D++   +         G+ ++  Y  + + +++C +++  + L G+  + L++    GLCS  G+ F      V+PFL LG+G+DD+F++   F    +   + F+D     G  +K  G ++ +TSI++   F + +   +PALR+F L   V ++  +      F A L++DL R    R  I  C+
Sbjct:  427 LDDILKSFSDVSVIRVAS-------GYLLMLAYACLTMLRWDCAKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDR---TGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCF 614          

Query:  304 LINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGL-FYGPMHNVIPFLMLGIGIDDMFVIMQCFDNL-RPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYKH-------KIEP-AEKESEADYEY 516
            L +I K + D++   +         G+ ++  Y  + + +++C +++  + L G+  + L++    GLCS  G+ F      V+PFL LG+G+DD+F++   F    +   + F+D     G  +K  G ++ +TSI++   F + +   +PALR+F L   V ++  +      F A L++DL R    R  I  C+         ++EP A  E  ++  Y
Sbjct:  413 LDDILKSFSDVSVIRVAS-------GYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDR---TGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTEPHSNTRY 625          

Query:  304 LINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGL-FYGPMHNVIPFLMLGIGIDDMFVIMQCFDNL-RPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCY 499
            L +I K + D++   +         G+ ++  Y  + + +++C +++  + L G+  + L++    GLCS  G+ F      V+PFL LG+G+DD+F++   F    +   + F+D     G  +K  G ++ +TSI++   F + +   +PALR+F L   V ++  +      F A L++DL R    R  I  C+
Sbjct:  427 LDDILKSFSDVSVIRVAS-------GYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDR---TGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCF 614          

Query:    1 MKFLDKVSSVIVGGFERFFYWYGKLISRSPWLFLIGCLVGAGLCGIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQSWDDVCKRVPVID-LPGLGKQVQGPGNLRQSPCDDP------------------------------SANDYDPSICLDSEIYCQVLDQSLSEACLETSILELFGYEAETYDNLDEESILKKVNEDTPTSVVFKRPIDIGQLL--SLTRDADGKIIGARAASLSWLGQVDLEHISDGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDH----ERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYKHKIEPAEKESEADYEYLSQKVFRIVGQIITKPLVK 535
            M  L K+S  I G  E+FFY +G  ++  P   +  CL+   +CG+G+     E    KLW+P  S+F  N EW+ A FP   R +  ++TA NVL P +++ +  IH+ V  + +T G++W+ +C ++P+   L    ++  G   L  +   +                               S + +     +  E YC ++++ L  AC E S  EL+ ++    DNL +E I++ VN +   S +F R ++       ++ R+  G++I A +  L W   ++   + +G      TG   D   LE+E K  D+ ++     M  G +     ++ + +I+  TI+ D   + +GF I+F YV IMLGKFN VE R  L++ GL+ +GL  +V+YGLCS   + YGP++ ++PFL+LGIGIDDMFVIMQC++NL    +  K      ERM G+ MKHAGV+ITVTS+TD   F VG+ST +P L+SFC+Y  VGIIAV+  QATFFVA  ALD +R+   RN      K+K +     S +   YL     RI+ + +  P  K
Sbjct:   33 MTSLQKISLAITGSMEKFFYRWGFFVATHPLKAISCCLLITSICGLGIFNFTMENRPDKLWIPRNSEFAQNTEWIRATFPSPIRTSFAIVTADNVLVPEVMRVILNIHERVKQIEVTGGKNWESLCYKLPITKFLSKRKRRSIGQAYLHSNSTTNSHTGLQILSNDFDDAFDDEFFSENSTLKPQTSESGFSQLFVVPDEFYCSIVNE-LDAACWEVSPAELWSFDKSLIDNLTQEEIIRVVNHEL-ISPIFGRSVNYTAEFGGNIVRNDLGEVISAGSVLLRWSIGINQTLLQEGRVVTDKTGEVADDDCLEWELKWIDLMKNISKD-MPPGINTYFVNSQSWMEISEATILDDGMQLAMGFIIMFFYVGIMLGKFNVVEQRPLLTIAGLSCVGLACVVSYGLCSLCFIVYGPVNKILPFLLLGIGIDDMFVIMQCWNNLFSSPLTNKSKLSIPERM-GMAMKHAGVSITVTSLTDVAAFGVGASTIMPGLQSFCIYAAVGIIAVFLLQATFFVACFALDQKRVEDRRNAFFLWIKYKEDEFIPNSWSQESYLQTLFNRILAKYLFTPWAK 600          

Query:    1 MKFLDKVSSVIVGGFERFFYWYGKLISRSPWLFLIGCLVGAGLCGIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQSWDDVCKRVPVID-LPGLGKQVQGPGNLRQSPCDDP------------------------------SANDYDPSICLDSEIYCQVLDQSLSEACLETSILELFGYEAETYDNLDEESILKKVNEDTPTSVVFKRPIDIGQLL--SLTRDADGKIIGARAASLSWLGQVDLEHISDGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDH----ERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYKHKIEPAEKESEADYEYLSQKVFRIVGQIITKPLVK 535
            M  L K+S  I G  E+FFY +G  ++  P   +  CL+   +CG+G+     E    KLW+P  S+F  N EW+ A FP   R +  ++TA NVL P +++ +  IH+ V  + +T G++W+ +C ++P+   L    ++  G   L  +   +                               S + +     +  E YC ++++ L  AC E S  EL+ ++    DNL +E I++ VN +   S +F R ++       ++ R+  G++I A +  L W   ++   + +G      TG   D   LE+E K  D+ ++     M  G +     ++ + +I+  TI+ D   + +GF I+F YV IMLGKFN VE R  L++ GL+ +GL  +V+YGLCS   + YGP++ ++PFL+LGIGIDDMFVIMQC++NL    +  K      ERM G+ MKHAGV+ITVTS+TD   F VG+ST +P L+SFC+Y  VGIIAV+  QATFFVA  ALD +R+   RN      K+K +     S +   YL     RI+ + +  P  K
Sbjct:   33 MTSLQKISLAITGSMEKFFYRWGFFVATHPLKAISCCLLITSICGLGIFNFTMENRPDKLWIPRNSEFAQNTEWIRATFPSPIRTSFAIVTADNVLVPEVMRVILNIHERVKQIEVTGGKNWESLCYKLPITKFLSKRKRRSIGQAYLHSNSTTNSHTGLQILSNDFDDAFDDEFFSENSTLKPQTSESGFSQLFVVPDEFYCSIVNE-LDAACWEVSPAELWSFDKSLIDNLTQEEIIRVVNHEL-ISPIFGRSVNYTAEFGGNIVRNDLGEVISAGSVLLRWSIGINQTLLQEGRVVTDKTGEVADDDCLEWELKWIDLMKNISKD-MPPGINTYFVNSQSWMEISEATILDDGMQLAMGFIIMFFYVGIMLGKFNVVEQRPLLTIAGLSCVGLACVVSYGLCSLCFIVYGPVNKILPFLLLGIGIDDMFVIMQCWNNLFSSPLTNKSKLSIPERM-GMAMKHAGVSITVTSLTDVAAFGVGASTIMPGLQSFCIYAAVGIIAVFLLQATFFVACFALDQKRVEDRRNAFFLWIKYKEDEFIPNSWSQESYLQTLFNRILAKYLFTPWAK 600          

Query:    4 LDKVSSVIVGGFERFFYWYGKLISRSPWLFLIGCLVGAGLCGIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQSWDDVCKRVPVIDLPGLGKQVQGPGNL--RQSPCDDPSANDYDPSICLDSEIYCQVLDQSLSEACLETSILELFGYEAETYDNLDEESILKKVNEDTPTSVVFKRPIDIGQLLS-LTRDADGKIIGARAASLSWLGQVDLEHIS-DGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYKHKIEPAEKESEADYEYLSQKVFRIVGQII-TKP 532
            L K+SS ++G  E FFY +G  I   PW  ++GCL    L  +G++   +E +  KLW+P  SDF+ +  WL   F    R  ++L+TAPNVL P +L+++ +I Q +  +N  DG +W+DVC R+PV+D     ++     NL   +   D    + +D    L  ++YC+++++ L  AC+E S+LEL+ +  +   NL EE I+K +N  T  S V+    D  QLL  + R+  G I+GA A    ++  VD   ++ D + + AGT        L++E K  D+ ++      E   ++     + + DI+A  +  D   + +G  ++F+Y+ +++ KFN VE R  +  +GL  I +  +V  G CS  G+ YGP+H  +PFL+LGIG+DDMFVI+ C+ NL          E+ IG T++HAG +ITVT++TD   F+VGS T LP+L+SFCLY   G++  Y FQATFFVA   LD RR+ +N N  L CYKH        SE   EY  Q ++ +  +++ TKP
Sbjct:   11 LRKLSSAVIGRLESFFYRFGFAIGCHPWRTILGCLSLVALSSLGILRFHQEKDPMKLWIPRNSDFIHDTNWLVNQFREGQRVQSILITAPNVLEPQVLRKLEDIQQKLENLN-ADGITWEDVCFRIPVVDFIFKRRKRDERENLILDKDHVDYEKDSVFDLGSLLGDDMYCRIINK-LDTACMEHSVLELWKFSQQKIHNLTEEKIIKALNR-TTVSPVYGHSTDYVQLLGGIRRNGTGHIVGASALLSLYMVHVDFLSVNFDENGNEAGTADWATTPILKWEQKFMDMMENVTRHAQE--IEVFYEAGRSFADISAAAMFQDIDKLIIGIVMMFIYIQLIVSKFNLVECRLLVGSIGLLCILMAFIVACGFCSLLGISYGPVHTALPFLLLGIGVDDMFVIVTCWKNLNLGNNQASLPEK-IGRTLQHAGTSITVTTVTDITAFLVGSLTILPSLQSFCLYAAAGLLMTYIFQATFFVACFVLDERRIEKNHNCALICYKHTNYKPNPCSEV--EYSKQFLYIVYSKVVFTKP 536          

Query:    4 LDKVSSVIVGGFERFFYWYGKLISRSPWLFLIGCLVGAGLCGIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQSWDDVCKRVPVIDLPGLGKQVQGPGNLRQSPCDDPSANDYDPSICLDSEIYCQVLDQSLSEACLETSILELFGYEAETYDNLDEESILKKVNEDTPTSVVFKRPIDIGQLLS-LTRDADGKIIGARAASLSWLGQVDLEHISDGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYKHKIEPAEKE-------SEADYEYLSQKVFRIVGQII 529
            L+KVS+ I G  E+ FY  G+ +  SPW+ ++  L+  G C  GL+   +E    KLW P  S    +  W++ NFP + R + VLL A +VLTPA+LK+   IH  V  V      SW+  C RV             GP                                      CL   +LEL+ ++    ++L +E IL+K+N+ T  S V K+   + Q L  + +++ G II A A S+S+  +   E        N  +G   D  T E+E+K  ++ +   P+     A++     + Y   + ++I GD  ++ VG+ ++ +YV +MLG+F  +  +A+L+L+G+  IGL I V++GL SAFG+FYGP+H+ +PFL+LGIG+DDMFVI+Q ++NL P     ++    +GL +KHAG +IT+TS+TDFL FM+G++T LPALRSFC++ G+GI+A +  QAT F A LALD +R  +NR+G   C K + +  E +        E   +Y+++ +  + G+II
Sbjct:   19 LNKVSNFITGSMEKGFYRLGRAVGGSPWITILISLIVCGACAAGLINFTQEARGDKLWTPEDSTTQKHKLWVDDNFPLELRVSTVLLVAGDVLTPAVLKEALTIHNKVKKVGNGTDISWEKFCFRV-------------GP-------------------------------------VCLNNGLLELWSFDEARINSLTKEDILRKINQPTIISPVTKKRFVLSQYLGGIEKNSSGSIIKAEATSMSYGVKYTPEL-------NENSGALEDKKTFEWEEKFGELMEGLEPS----SAELFYYTRRRYTTDSGDSIQGDVQLLSVGYILIIIYVAVMLGRFTRLNIKAWLALLGVVCIGLAIGVSFGLASAFGVFYGPVHSTLPFLLLGIGVDDMFVIVQAWNNLSPDTHKNQEVAERVGLALKHAGCSITITSLTDFLAFMIGATTILPALRSFCIFAGIGILADFALQATLFTAFLALDAKRQTKNRDGCCCCIKLREDYTESDRGKRDLLQEFMDKYVARAILSLPGKII 491          

Query:   12 VGGFERFFYWYGKLISRSPWLFLIGCLVGAGLCGIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQSWDDVCKRVPVIDLPGLGKQVQGPGNLRQS-----------PCDDPSAND-----------YDPSICLDSEIYCQVLDQSLSEACLETSILELFGYEAETYDNLDEESILKKVNEDTPTSVVFKRPIDIGQLL--SLTRDADGKIIGARAASLSWLGQVDLEHISDGSS-SNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHE---RMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYKHKIEPAEKESEADY 514
             G  E FFY +G  ++  P+  L  CL+   +C +GLM    E    KL +   S    + +WL  NFP   R++ V+  A NVLTP +  ++ ++ + +  + +  G+ W+++C ++PV    G+    +   NL  S             DD S N+           YD  + +D +IYC+ + +SL  AC + S LEL+ +     DNL ++ I++K+N +   S +F RP++    L   +T++  G++IGA +  + W   V+   +  G +  + GTG   D ++L +E +     + +   + ++         + + D+  +T+  D  ++ +G+ ++FVYV +MLG+FN +E R +LSL G++   L  LVT G+CS FGL +G ++ V+PFL+LG+G+DDMFVIMQC+ NL P+ +  K  E   + IG++++ AG +ITVTS+TD   F VG++T LP L+SFC+Y  VGIIAV+FFQ TFF+A LA+D +RL   RN  +F  ++        +EADY
Sbjct:   53 TGSVENFFYRWGYGVASHPYQTLTACLLFTLICSMGLMNFTYEDRPDKLLISQTSQLAYHTDWLRNNFPSPVRFSVVIFGADNVLTPQVFSKIMDVQERIENITV-KGRKWNEICFKLPVTK--GITVNSRKRRNLESSFEDDFFNSDINSNDDESINNTRNDAKQNDPYYDSMLSIDDDIYCEFV-ESLDSACWQISPLELWEFNRTIIDNLTQDEIIRKINHE-KISPIFGRPVNFTTELGGKITKNDKGEVIGATSIMVLWSISVNKTALKTGQAVRDDGTGELADEISLAWEKEWLAAMEQYDATINKSALSFNYVSGRSFGDVYKQTMYNDMKIVILGYAVMFVYVGLMLGRFNMIEQRPYLSLAGISCAALAGLVTCGICSTFGLAFGNVNKVLPFLLLGVGVDDMFVIMQCWKNLYPNVLAKKYKESIPQRIGISLRTAGASITVTSLTDMAAFAVGATTVLPGLKSFCIYSAVGIIAVFFFQVTFFIACLAIDQKRLENRRNAFIFWKQY--------TEADY 570          

Query:   21 WYGKLISRSPWLFLIGCLVGAGLCGIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQSWDDVCKRVPVIDLPGLGKQVQGPGNL--RQSPCDDPSANDYDPSICLDSEIYCQVLDQSLSEACLETSILELFGYEAETYDNLDEESILKKVNEDTPTSVVFKRPIDIGQLLS-LTRDADGKIIGARAASLSWLGQVDLEHIS-DGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYKHKIEPAEKESEADYEYLSQKVFRIVGQII-TKP 532
            W+G  I   PW  ++GCL    L  +G++   +E +  KLW+P  SDF+ +  WL   F    R  ++L+TAPNVL P +L+++ +I Q +  +N  DG +W+DVC R+PV+D     ++     NL   +   D    + +D    L  ++YC+++++ L  AC+E S+LEL+ +  +   NL EE I+K +N  T  S V+    D  QLL  + R+  G I+GA A    ++  VD   ++ D + + AGT        L++E K  D+ ++      E   ++     + + DI+A  +  D   + +G  ++F+Y+ +++ KFN VE R  +  +GL  I +  +V  G CS  G+ YGP+H  +PFL+LGIG+DDMFVI+ C+ NL          E+ IG T++HAG +ITVT++TD   F+VGS T LP+L+SFCLY   G++  Y FQATFFVA   LD RR+ +N N  L CYKH        SE   EY  Q ++ +  +++ TKP
Sbjct:    2 WFGFAIGCHPWRTILGCLSLVALSSLGILRFHQEKDPMKLWIPRNSDFIHDTNWLVNQFREGQRVQSILITAPNVLEPQVLRKLEDIQQKLENLN-ADGITWEDVCFRIPVVDFIFKRRKRDERENLILDKDHVDYEKDSVFDLGSLLGDDMYCRIINK-LDTACMEHSVLELWKFSQQKIHNLTEEKIIKALNR-TTVSPVYGHSTDYVQLLGGIRRNGTGHIVGASALLSLYMVHVDFLSVNFDENGNEAGTADWATTPILKWEQKFMDMMENVTRHAQE--IEVFYEAGRSFADISAAAMFQDIDKLIIGIVMMFIYIQLIVSKFNLVECRLLVGSIGLLCILMAFIVACGFCSLLGISYGPVHTALPFLLLGIGVDDMFVIVTCWKNLNLGNNQASLPEK-IGRTLQHAGTSITVTTVTDITAFLVGSLTILPSLQSFCLYAAAGLLMTYIFQATFFVACFVLDERRIEKNHNCALICYKHTNYKPNPCSEV--EYSKQFLYIVYSKVVFTKP 510          

Query:    2 KFLDKVSSVIVGGFERFFYWYGKLISRSPWLFLIGCLVGAGLCGIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQS---WDDVCKRVPVID--LPGLGKQVQGPGNLRQSPCDDPSANDYDPSICLDSEIYCQVLDQSLSEACLETSILELFGYEAETYDNLDEESILKKVN--EDTPTSVVFKRPIDIGQLLSLT-RDADGKIIGARAASLSWLGQVDLEHISDGSSSN-AGTGVPVDALTLEFEDKVFDIFQSFRPALMENGA------DILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVD-FKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYKHK------IEPAEKESEADYEYLSQK-VFRIVGQI 528
            + L ++   I    E FFY  G  I+R P ++++GC +   LC  GL   R+E N  KLWVP  SDFV + EWL   F    R   V++TA +VL P +L +M EI + + ++  TD Q    W DVC ++P+I        + ++      + P       ++DPS+   +++YC +L+ +L   CL  SIL+L+ Y ++   N  +  I+ K+N  E +PT      P++  +LL  T  D  GKI+ A+A    W+  VD + I+   + N  GT        L +E    +        L +N        +I     + + DI+A T+  D   + +G  ++ +YV I+L +FN +E R  L+  GL  +G   +V  GLCS FG+ YGP+H+ +PF+++G+G+DD+FV+M  ++ +  HE +  K  E  IG+ + HAG AI++TS+TD + F++G+ST LP+L SFC+Y  VG++  +  Q TFFVA   LD+RR+   RNG++ C  HK      ++P++  S   + +L  K V  + G+I
Sbjct:   16 RLLKRIPQNIATTVEHFFYSLGIQIARHPLIWILGCSIVVLLCLGGLYRFRQEKNPLKLWVPPDSDFVKDTEWLMERFDEGQRVETVIMTADDVLQPHVLFEMNEIIKRIMSME-TDSQPKLYWTDVCFKIPIISGYTNREKRDIEDDDFFEEEPAARSDKINFDPSVHAPTKVYCDILN-NLPTGCLILSILDLWEYNSDLIVNQTKADIINKINSAEMSPT---LGHPMNFTELLGGTVTDDTGKIVSAKALKTHWMLHVDFKKINMNDAGNDVGTSDWATLDVLNWESAFLNQLHLSSEYLKKNNLITNQSLEIWYEAGRSFGDISASTMFQDIKKVIIGIVLMTLYVQIILSRFNWLEWRFCLTSAGLLCVGGAFVVAVGLCSLFGVPYGPVHSSLPFMLMGLGVDDIFVMMASWEEVLSHESNRVKSVEERIGIMLSHAGAAISITSLTDVVAFIIGASTILPSLESFCIYAAVGVLVTFLLQVTFFVAVFTLDVRRIESKRNGVIPCIVHKNNQTSQVDPSKTLSWRIFNWLYSKIVLTLSGKI 560          

Query:    4 LDKVSSVIVGGFERFFYWYGKLISRSPWLFLIGCLVGAGLCGIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQSWDDVCKRVPV--IDL--PGLGKQVQGPGNLRQSPC--DDPSANDYDPSI----------------------CLDSEIYCQVLDQSLSEACLETSILELFGYEAETYDNLDEESILKKVNEDTPTSVVFKRPIDIGQLL--SLTRDADGKIIGARAASLSWLGQVDL--EHISDGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDH-----ERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYKHKIEPAEKESEADYE 515
            L+K+S       E FFY +G  ++  P  F+  C++   L G G++ ++EE+   KL +P+ +++  N EW+ +      R N   + A NVLTP ++K + ++H+ V  V+  DG++W DVC RVPV  IDL    L ++ +   N   S       S ND+D +                        +   +YC ++D +L EACLE++ +EL+ Y+ +   NL +E I++  N +   S VF R       L   + ++  G+II A +  ++W  +VD+  E I+D        G+  DA  LE+E +     + F    M +G  +    A  + DI  ET+I +  ++  GF I+F+YV +MLGK N +E R FL+L GL SI  ++++  G C+     +  ++ V+PFL+LGIGIDDMFVIMQCF+NL  H+   K       ER I LT+K+AGV+IT+TS+TD   F VG  +++P+LRSFCLY  VGI  ++ FQ T FVA LA+D +RL + RN  LFC +++ +   + S  +Y+
Sbjct:    9 LEKLSVRSKTSLENFFYRWGFTVATHPGKFVSICVLATVLFGSGIILIKEESRPDKLILPATAEYAVNTEWIRSKVAIPLRENYAGIVADNVLTPEVMKVLIDLHEKVKAVSTRDGKTWSDVCFRVPVTKIDLGEESLRRKRREANNSDASATISSSGSHNDWDSAFDDDFFKESTEEDVKPKQWTVYHSIPESLYCSIID-TLEEACLESNPVELWSYDKDVIYNLTQEEIIRVFNHEI-ISPVFGRKTKYKMELGGKIEKNEKGEIIKAESLLMTWDVKVDITQEMITDTQ------GLVGDAAGLEWEKEWIKSMKKFAKE-MPSGIKLHFLNAACWGDILDETLIQEGIVLVCGFGIMFLYVAMMLGKPNMIEQRPFLTLAGLGSIAFSLIIGCGFCAFLSFPFMTLNRVMPFLILGIGIDDMFVIMQCFNNLDQHDSLKKTKMGTIPER-IALTLKNAGVSITLTSLTDIAAFGVGCLSTIPSLRSFCLYAVVGISVLFIFQCTLFVACLAIDQKRLEERRNAFLFCIQYEEDKIPRSSTKNYD 547          

Query:    1 MKFLDKVSSVIVGGFERFFYWYGKLISRSPWLFLIGCLVGAGLCGIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQS----WDDVCKRVPVIDLPGLGKQVQGPGNLRQSPCDDPSAND--YDPSICLDSEIYCQVLDQSLSEACLETSILELFGYEAETYDNLDEESILKKVNEDTPTSVVFKRPIDIGQLLS-LTRDADGKIIGARAASLSWLGQVDLEHI-SDGSSSNAGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGIL 496
            + +L ++S  +     +FFY  G+ I+ +PW  +I C +    C +G +   +E +  KLWVP  S F+ +  W+  NF    R   V+LTAP+VLTP +L+++ EI + + ++ + +       W++VC +VP+I      ++ +   +   +    P      ++PS+ L S +YC ++++ L   CLE SILEL+ ++ E   NL +E I+ K+N  T  S V    ID  +LL  + RD  G+I+ A A   +W+  V+   + SD S + AGT   V    + +E K  +          ++   +     + Y DI+A+++  D   +  G  ++F+Y+ ++L KF+  E R  L  VGL S+G+  +   G+ S  G+ YGP+H  +PFL++G+G+DDMFV+M C+  +     +    ERM GL +KHAG +ITVTS+TD + F VGS T LP+L+SFC+Y   G++ ++FF  TF+VA   LD RR+   RN  +
Sbjct:   65 LSWLGRLSYHVSITIGQFFYRLGRFIANNPWRTIIACWLIVAFCSLGFLRFHQEKSPMKLWVPQNSKFLHDTNWVIDNFKEGNRIETVMLTAPDVLTPEVLQKLAEITEEIVSLTVINSHGKMVDWNEVCFKVPLIAEYTANERTKREDSQSLATTKRPKKQKPFFNPSVDLPSFMYCPLINR-LPVGCLERSILELWKFDREAISNLTKEQIVDKLN-STKISPVTGHTIDFSELLGGVQRDWTGRIVSATALYSNWMIHVNYSEVDSDVSGNAAGTEDWVTEEAMLWEGKFLEKLGEMGENYTDDETKMFYAAGRSYGDISADSMFKDIDKLVFGGVVMFIYMQLVLSKFSWTEFRIILGSVGLLSVGMGFIAGSGIVSILGVSYGPVHTCLPFLLMGLGVDDMFVMMACYRKIHETHANLPLPERM-GLMLKHAGASITVTSLTDIVAFAVGSITVLPSLQSFCIYAAFGVLMMFFFVITFYVAIFTLDERRIAARRNSFV 565          

Query:    3 FLDKVSSVIVGGFERFFYWYGKLISRSPWLFLIGCLVGAGLCGIGLMELREETNAFKLWVPSGSDFVANNEWLEANFPPDTRYNNVLLTAPNVLTPAILKQMFEIHQSVSTVNLTDGQSWDDVCKRVPVIDLPGLGKQVQGPGNLRQSPCDDPSANDYDPSICLDSEIYCQVLDQSLSEACLETSILELFGYEAETYDNLDEESILKKVNEDTPTSVVFKRPIDIGQLLS-LTRDADGKIIGARAASLSWLGQVDLEHISDGSSSN-AGTGVPVDALTLEFEDKVFDIFQSFRPALMENGADILINIAKGYDDIAAETIIGDAFMMPVGFTIVFVYVMIMLGKFNCVETRAFLSLVGLASIGLTILVTYGLCSAFGLFYGPMHNVIPFLMLGIGIDDMFVIMQCFDNLRPHEVDFKDHERMIGLTMKHAGVAITVTSITDFLVFMVGSSTSLPALRSFCLYCGVGIIAVYFFQATFFVAALALDLRRLNQNRNGILFCYKHKIEPAEKESEADYEYLSQKVFRIVGQ--IITKP 532
            F  K +  +V   E FFY  G  + + P+  +  C     L  +G +  ++E N  +LWVP  + FV ++EWL        +   V++T  +VLTPA++ Q+ +I + V TV  +   +  DVC R+P +D   L K + G            +    D S  +D  ++C  ++   SE C   SILEL+G++A+   N+ ++ IL  +N     S+ + R  D   LL  + R+  G II A+A    W   V+   I   +S N AGT +  +   L++E+    +  +    + +N   I  +  + + DI+ +++  D +++ +G +++ VYV +++ KFN +E R  L  +GL +IG++ +V  GLCS  G+FYGP+H  +PFL++G+G+DDMFVI+ C++ L+  +     HER +GL +KH GV+IT+TS TD + F++GSST LP L SFC+Y    ++  + F  TFFVA   LD RR+   RNG++   KHK   +   +E      +  +F+++    I+T P
Sbjct:   16 FSQKFTYSVVTYTELFFYKLGVCVGKHPFRTIGLCWALVLLSALGFLRFKQERNPLRLWVPPYTTFVRDSEWLIKTLDRAYQEEVVMITGDDVLTPAVIHQLLDIDKRVRTVRSSGNLTLQDVCFRIPKVD-KALLKMIDG------------NETGKDQSTTMDPALFCSFVEAMKSE-CYTRSILELWGFKAKKIANITKDDILWAINTFDRNSL-YGRLKDYNDLLGGVVRNESGHIISAKAIQNIWYLNVNFSSIDMTTSGNDAGTALWANDEGLDWENAFLKLMNN----ITKNFNHIYYSAGRSFGDISNDSMFSDMYLLVIGVSVMIVYVQLVISKFNWLEARIVLGFIGLLTIGMSFVVGAGLCSLIGIFYGPVHTSLPFLLMGLGVDDMFVILACWEELKEEDRKLPIHER-VGLMLKHGGVSITITSFTDIIAFLIGSSTILPCLESFCIYAAACVLMTFIFAITFFVACFVLDQRRVENKRNGVVPWIKHK--DSYIPNECSQRKYTNSIFKMIYSKVILTTP 527