RNAi

Search or browse a total of 415 RNA interference (RNAi) experiments available in LiceBase. RNA interference is a technique to "silence" a gene's expression by injection of double-stranded RNA (dsRNA) or short-interfering RNA (siRNA).
At SLRC, dsRNA has been widely used and can be applied at Nauplia and pre-adult and adult stages of the salmon louse. The animals are then compared to control animals for differences in phenotype. Most are only inspected visually, but some also histologically or measurements, e.g. of egg-string length. Note: "No visible phenotype" means that no difference could be observed under the outlined experimental conditions and using the observation methods applied.

Select one or many phenotypes
List of all RNAi experiments
Gallery Image Title Primary target ID Developmental Stage CV Phenotype Number of Individuals (Start/End) Organism Efficacy of Knock Down Postedsort ascending Publication
271 R F170 (DcytB) EMLSAG00000005522, EMLSAG00000005522-688288 (gene) Lepeophtheirus salmonis
DcytB
PreAdult2, Adult no visible phenotype 39/19 Lepeophtheirus salmonis 27 July, 2015 - 11:29
272 M F119 (DMT-1) EMLSAG00000004199, EMLSAG00000004199-686965 (gene) Lepeophtheirus salmonis
DMT-1
PreAdult2, Adult no visible phenotype 40/13 Lepeophtheirus salmonis F>45.00% 24 July, 2015 - 16:30
273 C F4 (CopB2) EMLSAT00000000903, EMLSAT00000000903-696750 (mRNA) Lepeophtheirus salmonis
LsCopB2
PreAdult2, Adult feeding, reduced nutrient uptake, no blood uptake, female reproduction, no eggstrings, survival, reduced 39 Lepeophtheirus salmonis F>82.00% 24 July, 2015 - 16:11
RNA interference mediated knockdown of the KDEL receptor and...
274 Y F203 EMLSAG00000000387, EMLSAG00000000387-683153 (gene) Lepeophtheirus salmonis
387
PreAdult2 7/3 Lepeophtheirus salmonis F>25.00% 10 June, 2015 - 12:36
275 Y F202 EMLSAG00000000496, EMLSAG00000000496-683262 (gene) Lepeophtheirus salmonis
496
PreAdult2, Adult no visible phenotype 30/11 Lepeophtheirus salmonis F>74.00% 10 June, 2015 - 12:32
276 Y F200 EMLSAG00000000562, EMLSAG00000000562-683328 (gene) Lepeophtheirus salmonis
562
PreAdult2, Adult no visible phenotype 30/15 Lepeophtheirus salmonis F>21.00% 10 June, 2015 - 12:29
277 RNAi_U 5667 EMLSAG00000005667, EMLSAG00000005667-688433 (gene) Lepeophtheirus salmonis PreAdult2 no eggstrings 120/28 Lepeophtheirus salmonis F>50.00% 10 June, 2015 - 10:15
278 B F2+F3 (IRP1+IRP2) EMLSAT00000007801, EMLSAT00000007801-703648 (mRNA) Lepeophtheirus salmonis, EMLSAT00000000118, EMLSAT00000000118-695965 (mRNA) Lepeophtheirus salmonis
LsIRP1B, LsIRP1A
PreAdult2, Adult female reproduction, shorter eggstrings 39/23 Lepeophtheirus salmonis F>44.00% 29 April, 2015 - 16:21
Characterisation of iron regulatory protein 1A and 1B in the...
279 A F4 (CopB2) EMLSAT00000000903, EMLSAT00000000903-696750 (mRNA) Lepeophtheirus salmonis
LsCopB2
PreAdult2, Adult feeding, reduced nutrient uptake, no blood uptake, female reproduction, no eggstrings, survival, reduced 39/5 Lepeophtheirus salmonis F>65.00% 29 April, 2015 - 15:44
RNA interference mediated knockdown of the KDEL receptor and...
280 A F3 (IRP2) EMLSAT00000007801, EMLSAT00000007801-703648 (mRNA) Lepeophtheirus salmonis
LsIRP1B
PreAdult2, Adult female reproduction, shorter eggstrings 39/23 Lepeophtheirus salmonis F>45.00% 29 April, 2015 - 15:16
Characterisation of iron regulatory protein 1A and 1B in the...

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