RNAi

Search or browse a total of 415 RNA interference (RNAi) experiments available in LiceBase. RNA interference is a technique to "silence" a gene's expression by injection of double-stranded RNA (dsRNA) or short-interfering RNA (siRNA).
At SLRC, dsRNA has been widely used and can be applied at Nauplia and pre-adult and adult stages of the salmon louse. The animals are then compared to control animals for differences in phenotype. Most are only inspected visually, but some also histologically or measurements, e.g. of egg-string length. Note: "No visible phenotype" means that no difference could be observed under the outlined experimental conditions and using the observation methods applied.

Select one or many phenotypes
List of all RNAi experiments
Gallery Image Title Primary target ID Developmental Stage CV Phenotype Number of Individuals (Start/End) Organism Efficacy of Knock Down Postedsort descending Publication
221 X F210 EMLSAT00000011448, EMLSAT00000011448-707295 (mRNA) Lepeophtheirus salmonis PreAdult2 Eggstrings curly and strange. 30/5 Lepeophtheirus salmonis 14 March, 2017 - 22:02
222 AG-F286 EMLSAT00000011173, EMLSAT00000011173-707020 (mRNA) Lepeophtheirus salmonis, EMLSAT00000011448, EMLSAT00000011448-707295 (mRNA) Lepeophtheirus salmonis PreAdult2 Slightly curly eggstrings. 29/19 Lepeophtheirus salmonis 16 March, 2017 - 11:15
223 AF F231 EMLSAT00000005273, EMLSAT00000005273-701120 (mRNA) Lepeophtheirus salmonis
EMLSAG00000005273
padII/ad, Adult 30/14 Lepeophtheirus salmonis F>99.40% 17 March, 2017 - 12:50
224 F231 Nauplia EMLSAT00000005273, EMLSAT00000005273-701120 (mRNA) Lepeophtheirus salmonis
EMLSAG00000005273
Nauplius I, chalamus II/padI 550/201 Lepeophtheirus salmonis F>96.50% 17 March, 2017 - 14:25
225 AI F316 EMLSAT00000006642, EMLSAT00000006642-702489 (mRNA) Lepeophtheirus salmonis
EMLSAT00000006642
PreAdult2, Adult 30/10 Lepeophtheirus salmonis F>97.00% 23 March, 2017 - 13:32
226 EMLSAT00000006642_copepodites EMLSAT00000006642, EMLSAT00000006642-702489 (mRNA) Lepeophtheirus salmonis Copepodid 420/66 Lepeophtheirus salmonis F>86.00% 4 December, 2017 - 10:28
227 ExpC EMLSAT00000009293 EMLSAT00000009293, EMLSAT00000009293-705140 (mRNA) Lepeophtheirus salmonis
Unknown
Copepodid, Copepodid host related phenotype, modulation of immune response 420/50 Lepeophtheirus salmonis F>99.00% 4 December, 2017 - 10:32
228 LsHSCARB - a putative intestinal heme receptor EMLSAG00000005382, EMLSAG00000005382-688148 (gene) Lepeophtheirus salmonis PreAdult2 Shorter egg-strings, 60% less heme, lower hatching
feeding, reduced nutrient uptake
30/15 Lepeophtheirus salmonis F>95.00% 4 December, 2017 - 10:55
A scavenger receptor B (CD36)-like protein is a potential...
229 AH F242 EMLSAG00000001206, EMLSAG00000001206-683972 (gene) Lepeophtheirus salmonis
T3_1206
PreAdult2, Adult no visible phenotype 30/19 Lepeophtheirus salmonis 22 March, 2018 - 14:27
230 AH F243 EMLSAG00000005306, EMLSAG00000005306-688072 (gene) Lepeophtheirus salmonis
T4_5306
PreAdult2, Adult No visible phenotype
no visible phenotype
30/17 Lepeophtheirus salmonis 22 March, 2018 - 14:30

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