RNAi

Search or browse a total of 415 RNA interference (RNAi) experiments available in LiceBase. RNA interference is a technique to "silence" a gene's expression by injection of double-stranded RNA (dsRNA) or short-interfering RNA (siRNA).
At SLRC, dsRNA has been widely used and can be applied at Nauplia and pre-adult and adult stages of the salmon louse. The animals are then compared to control animals for differences in phenotype. Most are only inspected visually, but some also histologically or measurements, e.g. of egg-string length. Note: "No visible phenotype" means that no difference could be observed under the outlined experimental conditions and using the observation methods applied.

Select one or many phenotypes
List of all RNAi experiments
Gallery Image Titlesort descending Primary target ID Developmental Stage CV Phenotype Number of Individuals (Start/End) Organism Efficacy of Knock Down Posted Publication
201 L F95 EMLSAG00000005923, EMLSAG00000005923-688689 (gene) Lepeophtheirus salmonis
UN17_g1274
PreAdult, Adult no visible phenotype 29/18 Lepeophtheirus salmonis 7 May, 2013 - 10:38
202 L F97 EMLSAG00000002641, EMLSAG00000002641-685407 (gene) Lepeophtheirus salmonis PreAdult, Adult One animal for sectioning
female reproduction
29/7 Lepeophtheirus salmonis 7 May, 2013 - 10:13
203 L F98 placeholder for unknown sequence, geneofdeath (protein_coding_gene) Lepeophtheirus salmonis
Kiran
PreAdult, Adult One animal for sectioning
female reproduction
30 Lepeophtheirus salmonis 22 January, 2014 - 10:44
204 LsCHS1 EMLSAT00000002852, EMLSAT00000002852-698699 (mRNA) Lepeophtheirus salmonis PreAdultI males In preAdultII: Could not complete molting or had t
Molting, developmental defect
60 Lepeophtheirus salmonis F>80.00% 7 May, 2018 - 23:13
205 LsCHS1 EMLSAT00000002852, EMLSAT00000002852-698699 (mRNA) Lepeophtheirus salmonis
LsCHS1
PreAdult2 None 60/4 Lepeophtheirus salmonis 14 June, 2018 - 13:05
206 LsCHS1 EMLSAT00000002853, EMLSAT00000002853-698700 (mRNA) Lepeophtheirus salmonis
LsCHS1
PreAdult1, PreAdult2 Cuticle disorder 60/29 Lepeophtheirus salmonis 19 June, 2018 - 16:56
207 LsCHS2 EMLSAT00000007308, EMLSAT00000007308-703155 (mRNA) Lepeophtheirus salmonis
LsCHS2
PreAdult1 , Adult None 9 Lepeophtheirus salmonis F>60.00% 14 June, 2018 - 11:54
208 LsCHS2 EMLSAT00000007308, EMLSAT00000007308-703155 (mRNA) Lepeophtheirus salmonis
LsCHS2
PreAdult2, Adult None 60/12 Lepeophtheirus salmonis 14 June, 2018 - 13:35
209 LsHSCARB - a putative intestinal heme receptor EMLSAG00000005382, EMLSAG00000005382-688148 (gene) Lepeophtheirus salmonis PreAdult2 Shorter egg-strings, 60% less heme, lower hatching
feeding, reduced nutrient uptake
30/15 Lepeophtheirus salmonis F>95.00% 4 December, 2017 - 10:55
A scavenger receptor B (CD36)-like protein is a potential...
210 LsHSCARB on free living stages EMLSAT00000005382, EMLSAT00000005382-701229 (mRNA) Lepeophtheirus salmonis, EMLSAG00000005382, EMLSAG00000005382-688148 (gene) Lepeophtheirus salmonis Nauplius I, Copepodid none
no visible phenotype
300/250 Lepeophtheirus salmonis F>99.00% 23 April, 2018 - 10:06
A scavenger receptor B (CD36)-like protein is a potential...

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