RNAi

Search or browse a total of 353 RNA interference (RNAi) experiments available in LiceBase. RNA interference is a technique to "silence" a gene's expression by injection of double-stranded RNA (dsRNA) or short-interfering RNA (siRNA).
At SLRC, dsRNA has been widely used and can be applied at Nauplia and pre-adult and adult stages of the salmon louse. The animals are then compared to control animals for differences in phenotype. Most are only inspected visually, but some also histologically or measurements, e.g. of egg-string length. Note: "No visible phenotype" means that no difference could be observed under the outlined experimental conditions and using the observation methods applied.

Select one or many phenotypes
List of all RNAi experiments
Gallery Image Titlesort descending Primary target ID Developmental Stage CV Phenotype Number of Individuals (Start/End) Organism Efficacy of Knock Down Posted Publication
91 D F29 EMLSAG00000006214, EMLSAG00000006214-688980 (gene) Lepeophtheirus salmonis
g2282_trehalose
PreAdult2 a bit short eggstrings (?), other wise normal.
female reproduction
36/12 Lepeophtheirus salmonis F>59.00% 6 March, 2013 - 14:49
92 D F31 EMLSAT00000004214, EMLSAT00000004214-700061 (mRNA) Lepeophtheirus salmonis
TOR
PreAdult2 female reproduction, shorter eggstrings 40/14 Lepeophtheirus salmonis F>0.10% 4 February, 2015 - 13:36
Molecular characterization and functional analysis of...
93 D F32 EMLSAT00000003443, EMLSAT00000003443-699290 (mRNA) Lepeophtheirus salmonis
NLG3408_TSC1
PreAdult2 no visible phenotype 40/7 Lepeophtheirus salmonis F>33.00% 4 February, 2015 - 13:46
Molecular characterization and functional analysis of...
94 D F32/F33 EMLSAT00000002599, EMLSAT00000002599-698446 (mRNA) Lepeophtheirus salmonis, EMLSAT00000003443, EMLSAT00000003443-699290 (mRNA) Lepeophtheirus salmonis
g18363_TSC2, NLG3408_TSC1
PreAdult2 female reproduction, shorter eggstrings 40/14 Lepeophtheirus salmonis F>30.00% 5 February, 2015 - 08:46
Molecular characterization and functional analysis of...
95 D F33 EMLSAT00000002599, EMLSAT00000002599-698446 (mRNA) Lepeophtheirus salmonis
g18363_TSC2
PreAdult2 female reproduction, shorter eggstrings 40/11 Lepeophtheirus salmonis F>72.00% 4 February, 2015 - 13:53
Molecular characterization and functional analysis of...
96 D F39 EMLSAG00000005090, EMLSAG00000005090-687856 (gene) Lepeophtheirus salmonis
EcR
PreAdult2 No eggstring production
female reproduction, no eggstrings
39/16 Lepeophtheirus salmonis F>0.00% 12 December, 2014 - 10:54
Molecular characterisation of the salmon louse,...
97 disembodied EMLSAT00000005394, EMLSAT00000005394-701241 (mRNA) Lepeophtheirus salmonis
dib
Nauplius1 non Lepeophtheirus salmonis F>15.00% 17 November, 2015 - 13:10
98 E F34 EMLSAG00000003242, EMLSAG00000003242-686008 (gene) Lepeophtheirus salmonis
g7499_LsRaptor
PreAdult2, Adult female reproduction, egg string deformation, no eggstrings 39/24 Lepeophtheirus salmonis F>50.00% 12 March, 2013 - 09:05
Molecular characterization and functional analysis of...
99 E F35 EMLSAT00000011088, EMLSAT00000011088-706935 (mRNA) Lepeophtheirus salmonis
g18363_LsRictor
PreAdult2 no visible phenotype 40/23 Lepeophtheirus salmonis F>35.00% 4 February, 2015 - 14:37
Molecular characterization and functional analysis of...
100 E F42 EMLSAT00000005071, EMLSAT00000005071-700918 (mRNA) Lepeophtheirus salmonis
g13677_Rheb
PreAdult2, Adult Low reproduction and most are missing blood in the
feeding, reduced nutrient uptake, no blood uptake, female reproduction, no eggstrings
39/25 Lepeophtheirus salmonis F>60.00% 12 March, 2013 - 10:38
Molecular characterization and functional analysis of...

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