Search or browse a total of 415 RNA interference (RNAi) experiments available in LiceBase. RNA interference is a technique to "silence" a gene's expression by injection of double-stranded RNA (dsRNA) or short-interfering RNA (siRNA).
At SLRC, dsRNA has been widely used and can be applied at Nauplia and pre-adult and adult stages of the salmon louse. The animals are then compared to control animals for differences in phenotype. Most are only inspected visually, but some also histologically or measurements, e.g. of egg-string length. Note: "No visible phenotype" means that no difference could be observed under the outlined experimental conditions and using the observation methods applied.

Select one or many phenotypes
List of all RNAi experiments
Gallery Image Title Primary target ID Developmental Stage CV Phenotype Number of Individuals (Start/End) Organism Efficacy of Knock Down Postedsort descending
371 EMLSAT00000005299 cop + infection EMLSAT00000005299, EMLSAT00000005299-701146 (mRNA) Lepeophtheirus salmonis
Nauplius1, chalimus and preadult no proper visible phenotype but maybe quicker deve
no visible phenotype
180/52 Lepeophtheirus salmonis 14 June, 2018 - 14:05
372 EMLSAT00000007048 cop + infection EMLSAT00000007048, EMLSAT00000007048-702895 (mRNA) Lepeophtheirus salmonis Nauplius1, Copepodid no visible phenotype
no visible phenotype
180/45 Lepeophtheirus salmonis 14 June, 2018 - 14:10
373 ExpD EMLSAT00000009293 EMLSAT00000009293, EMLSAT00000009293-705140 (mRNA) Lepeophtheirus salmonis
Adult, Adult no visible phenotype 50/50 Lepeophtheirus salmonis F>99.00% 14 June, 2018 - 14:17
374 LsCHS1 EMLSAT00000002853, EMLSAT00000002853-698700 (mRNA) Lepeophtheirus salmonis
PreAdult1, PreAdult2 Cuticle disorder 60/29 Lepeophtheirus salmonis 19 June, 2018 - 16:56
375 EMLSAT00000001458 cop + infection_b EMLSAT00000001458, EMLSAT00000001458-697305 (mRNA) Lepeophtheirus salmonis
Nauplius1, Copepodid no lice survived to the end of experiment, where c
survival, reduced
100 Lepeophtheirus salmonis 6 August, 2018 - 16:19
376 10397&5417 KD, first eggstring EMLSAT00000010397, EMLSAT00000010397-706244 (mRNA) Lepeophtheirus salmonis, EMLSAT00000005417, EMLSAT00000005417-701264 (mRNA) Lepeophtheirus salmonis
EMLSAT00000010397, EMLSAT00000005417
PreAdult2 10 Lepeophtheirus salmonis 16 August, 2018 - 13:17
377 AR F376 EMLSAT00000004347 EMLSAG00000004347, EMLSAG00000004347-687113 (gene) Lepeophtheirus salmonis
PreAdult2 shorter eggstring 30/10 Lepeophtheirus salmonis 21 September, 2018 - 19:44
378 AS F379 EMLSAT00000008518, EMLSAT00000008518-704365 (mRNA) Lepeophtheirus salmonis
PreAdult2 reproduction, female reproduction, abnormal egg strings 30/15 Lepeophtheirus salmonis F>90.00% 21 November, 2018 - 09:46
379 AR F244 EMLSAT00000010957 EMLSAT00000010957, EMLSAT00000010957-706804 (mRNA) Lepeophtheirus salmonis
PreAdult2 No visible phenotype
no visible phenotype
30/15 Lepeophtheirus salmonis 21 November, 2018 - 09:50
380 RNAi_AS 11366+12062 EMLSAG00000011366, EMLSAG00000011366-694132 (gene) Lepeophtheirus salmonis, EMLSAG00000012062, EMLSAG00000012062-694828 (gene) Lepeophtheirus salmonis
preadult II femal developmental defect, female reproduction Lepeophtheirus salmonis F>90.00% 21 November, 2018 - 09:58